Turner Syndrome is a common genetic disorder. Seventy percent of adults with Turner Syndrome have abnormalities in glucose metabolism which can lead to diabetes. The current screening guidelines for diabetes in Turner Syndrome are not specific and involve a fasting blood sugar once a year. The objective of this study is to determine if there are abnormalities in glucose metabolism and pancreatic function in young girls with Turner Syndrome. The study hypothesis is that pancreatic dysfunction (specifically of the beta cells that make insulin) is more prevalent in girls with Turner Syndrome compared to healthy controls ...
... is a chromosomal disorder that usually affects development in females. Symptoms differ among individuals, but may include shortened stature, infertility, extra skin on the neck (webbed neck), puffiness or swelling (lymphedema) of the hands and feet, skeletal abnormalities, heart defects, and kidney problems. Females without Turner syndrome have 2 full X chromosomes in each of their cells. An individual with Turner syndrome is missing all or part of one X chromosome. Although it is genetic, it is typically not inherited. Treatment may include growth hormone therapy for short stature and estrogen therapy to help stimulate sexual development. Assisted reproduction techniques can help some women with Turner syndrome become pregnant ...
Childrens Mercys Turner Syndrome Clinic, Great HeighTS Clinic, is one of the largest Turner Syndrome programs in the country, providing comprehensive care for more than 70 children in the region. One-day clinics are held every four months giving Turner Syndrome patients and families an opportunity to meet with multiple pediatric specialists in one convenient location. Each childs visit includes complete lab and X-ray procedures. During the one-day clinic, families and patients are invited to take part in a social activity at the hospital in order to increase communication and education regarding the rare disease ...
Turner syndrome is the only sex chromosome disorder in which complete absence of an X chromosome is compatible with life. The loss of one of the sex chromosomes in Turner syndrome probably occurs after the zygote has formed or just after the fusion of the gametes. It has been determined that approximately 50% of cases have a 45,X karyotype with the remainder having mosaic karyotypes. In addition, it has been found that in 70 to 80 % of the cases, the retained X is maternal in origin. Researchers have begun to speculate as to the possibility that genes are present on the X chromosome which are expressed differently depending on the parental origin of the X chromosome. The effects of genomic imprinting can be analyzed from the standpoint of physical and physiologic parameters in females with Turner syndrome.. ...
Growth hormone therapy has been shown in several studies to increase final height in girls with Turner syndrome by up to 3-4 inches. Turner syndrome is one of the three FDA approved indications for growth hormone treatment in children.. At this time, growth hormone therapy should be considered as soon as a Turner girl has dropped below the fifth percentile of the normal female growth curve.. Growth hormone is safe and has only a few rare adverse side effects. A pediatric endocrinologist monitors girls on growth hormone therapy every 3-4 months for response and possible side effects. Currently, patients receive growth hormone as a daily subcutaneous injection (just under the skin).. In girls who have ovarian failure, estrogen is started sometime between ages 12 and 14 years to allow for pubertal development. Progesterone (another important hormone that the ovary makes) is typically added 1 to 2 years after estrogen is started. Both of these hormones can be taken orally as tablets; estrogen is ...
Growth hormone therapy has been shown in several studies to increase final height in girls with Turner syndrome by up to 3-4 inches. Turner syndrome is one of the three FDA approved indications for growth hormone treatment in children.. At this time, growth hormone therapy should be considered as soon as a Turner girl has dropped below the fifth percentile of the normal female growth curve.. Growth hormone is safe and has only a few rare adverse side effects. A pediatric endocrinologist monitors girls on growth hormone therapy every 3-4 months for response and possible side effects. Currently, patients receive growth hormone as a daily subcutaneous injection (just under the skin).. In girls who have ovarian failure, estrogen is started sometime between ages 12 and 14 years to allow for pubertal development. Progesterone (another important hormone that the ovary makes) is typically added 1 to 2 years after estrogen is started. Both of these hormones can be taken orally as tablets; estrogen is ...
Growth hormone therapy has been shown in several studies to increase final height in girls with Turner syndrome by up to 3-4 inches. Turner syndrome is one of the three FDA approved indications for growth hormone treatment in children.. At this time, growth hormone therapy should be considered as soon as a Turner girl has dropped below the fifth percentile of the normal female growth curve.. Growth hormone is safe and has only a few rare adverse side effects. A pediatric endocrinologist monitors girls on growth hormone therapy every 3-4 months for response and possible side effects. Currently, patients receive growth hormone as a daily subcutaneous injection (just under the skin).. In girls who have ovarian failure, estrogen is started sometime between ages 12 and 14 years to allow for pubertal development. Progesterone (another important hormone that the ovary makes) is typically added 1 to 2 years after estrogen is started. Both of these hormones can be taken orally as tablets; estrogen is ...
Growth hormone therapy has been shown in several studies to increase final height in girls with Turner syndrome by up to 3-4 inches. Turner syndrome is one of the three FDA approved indications for growth hormone treatment in children.. At this time, growth hormone therapy should be considered as soon as a Turner girl has dropped below the fifth percentile of the normal female growth curve.. Growth hormone is safe and has only a few rare adverse side effects. A pediatric endocrinologist monitors girls on growth hormone therapy every 3-4 months for response and possible side effects. Currently, patients receive growth hormone as a daily subcutaneous injection (just under the skin).. In girls who have ovarian failure, estrogen is started sometime between ages 12 and 14 years to allow for pubertal development. Progesterone (another important hormone that the ovary makes) is typically added 1 to 2 years after estrogen is started. Both of these hormones can be taken orally as tablets; estrogen is ...
I am a 38 year old female with Turner Syndrome, diagnosed at age 17. Each doctor I have gone to keep on estrogen therapy never seemed concerned with my heart, kidneys or any other possible hidden problems I might have. When I want to discuss tests to ensure my health, they change the subject. My karyotype is 45XO, which indicates pure Turners, but even my present doctor, who is a specialist, doesnt seem concerned with any other health problems besides hormone therapy. Am I just being overconcerned? From the research Ive done it is not uncommon for Turner girls and women to have underlying health problems. Turner Syndrome is caused by the complete or partial absence of one of the two X chromosomes usually found in women. It effects approximately one in every 3000 women and is either diagnosed at the time of birth, or at the time of adolescence when menstruation fails to begin. It is indicated by minimal sexual development, including the failure of menstruation to begin, and the lack of breast ...
Babies with Turner syndrome may grow at a normal rate until three years of age. After this age, their growth slows down.. At puberty (usually at age 8 to 14), a girl with Turner syndrome will not have the normal growth spurt, even with female oestrogen hormone replacement (HRT). Girls with Turner syndrome are typically short in relation to the height of their parents. On average, adult women with untreated Turner syndrome are 20cm (8 inches) shorter than adult women without the syndrome. Treatment with additional high-dose growth hormone reduces this difference by about 5cm (about 2 inches) on average.. Read more about growth hormone treatment in Turner syndrome.. ...
In 1938, Henry Turner first described Turner syndrome, which is one of the most common chromosomal abnormalities. More than 95% of adult women with Turner syndrome exhibit short stature and infertility.
In 1938, Henry Turner first described Turner syndrome, which is one of the most common chromosomal abnormalities. More than 95% of adult women with Turner syndrome exhibit short stature and infertility.
Most people with Turner syndrome benefit from growth hormone treatment during childhood and early teens. This will help them achieve as much height as possible. Growth hormone treatment involves regular injections of somatropin. In some cases, the doctor may also recommend an androgen known as oxandrolone in conjunction with the growth hormone. Most patients with the condition require life-long hormone therapy. Estrogen hormone therapy typically begins at the normal age of puberty and continues to the normal age of menopause. The hormones aid in growth and sexual development. Other treatments depend on the exact nature of the patients symptoms and complications. For example, surgery may be necessary to correct specific heart abnormalities. It is possible for some women with Turner syndrome to become pregnant with the help of a specially tailored hormone therapy and donor embryos. These pregnancies are considered high-risk and should be monitored carefully by an OB/GYN familiar with the ...
Turner syndrome can be defined as loss or abnormality of the second X chromosome in at least one cell line in a phenotypic female. In the majority of affected...
TY - JOUR. T1 - Age-related anti-thyroid antibodies and thyroid abnormalities in turner syndrome. AU - Germain, E. L.. AU - Plotnick, L. P.. PY - 1986/1/1. Y1 - 1986/1/1. N2 - One hundred pediatric patients with Turner syndrome were studied to determine the correlation between the presence of anti-thyroid antibodies with age and karyotype, and the value of anti-thyroid antibody titers as predictors of subsequent thyroid abnormalities. (54 patients = 45,X; 46 = other karyotypes). The frequency of positive titers of anti-thyroid antibodies increased linearly with cumulative age. Anti-parietal cell and anti-adrenocortical cell antibodies were not increased in these patients (1.3 and 2.6% respectively). The ability to use positive anti-thyroid antibody titers to predict the development of thyroid abnormalities increased from age 10 years and became statistically significant at ages 13-17 years for the whole group as well as 45,X patients. None of the patients had clinical symptoms of thyroid ...
How to Diagnose Turner Syndrome. Turner Syndrome (TS) is a relatively rare condition that affects only females and is caused by a sex chromosome abnormality. It can cause a wide range of physical and developmental challenges, but early...
In women with Turner syndrome, the risk of death from aortic dissection or rupture during pregnancy may be 2%, and this risk persists during the postpartum period owing to pregnancy-related aortic changes. Turner syndrome is a relative contraindication for pregnancy; however, it is an absolute contraindication for pregnancy in a patient with a documented cardiac anomaly. This document replaces the 2008 document of the same name.. ...
A recent study accepted for publication in The Endocrine Societys Journal of Clinical Endocrinology & Metabolism (JCEM) has demonstrated a novel and accurate test for early diagnosis of Turner syndrome. Turner syndrome affects ...
Welcome to the Turner Syndrome (TS) Clinic at MassGeneral Hospital for Children. Our clinic provides a medical home for people of all ages with Turner syndrome.
Fertility of women with Turner Syndrome is now being more interested due to the new improvements in assisted reproductive techniques. Turner Syndrome is characterized by the premature atresia of ovarian follicules. Atresia starts at intrauterine period and continues till all ovarian follicules go to atresia.
Even though there is no cure, the prognosis for Turner syndrome is generally good. As this eMedTV page explains, a womans Turner syndrome prognosis is affected by the cause and symptoms of her condition, as well as any other illnesses she may have.
The Turner Syndrome Support Society is a national charity caring for the needs of those with Turner Syndrome throughout the United Kingdom.
Looking for male Turner's syndrome? Find out information about male Turner's syndrome. Ullrich-Turner syndrome Explanation of male Turner's syndrome
Henry Turner discovered Turner syndrome by observing patients with endocrine disorders, according to Healio.com. His work as a consulting endocrinologist paved the way to his discovery of the...
Correct answer: C. Turner Syndrome is specific to females. Cardiovascular and kidney problems are common, with an increased risk for developing hypertension in adulthood. Persons with Turner Syndrome are at a significantly increased risk of developing Type II diabetes. The lack of ovarian development is also characteristic of the syndrome, typically resulting in infertility/sterility. The Turner Syndrome Society notes that "Fertility without assisted reproduction therapy is rare - (less than 1%)." (See references below). A - At least daily monitoring of blood pressure is indicated. The woman verbalized an understanding of the need to monitor her blood pressure. This does not demonstrate a need for further health education.. B - Persons with Turner Syndrome have twice the risk of the general population of developing diabetes (nih). Polyphagia and polyuria are both signs of diabetes. The womans statement indicates that she understands that she must still monitor for signs of diabetes. This does ...
Turner syndrome (TS), which results from the complete or partial absence of an X chromosome in phenotypic females, occurs in ∼1 in 2000 live births (Lippe, 1991). The TS phenotype is characterized by short stature, gonadal dysgenesis, and a cognitive profile of relative strengths in verbal skills (Ross et al., 2000) with impairments in visuospatial and arithmetic processing (Waber, 1979; Pennington et al., 1985; Bender et al., 1993; Murphy et al., 1994; Rovet and Ireland, 1994), motor function (Ross et al., 1996), executive function (McCauley et al., 1987), and social cognition (Ross et al., 2000). Individual variation in the physical and cognitive characteristics in TS are believed to be attributable to a number of factors, including mosaic karyotypes consisting of partial X or Y chromosome fragments and possibly X-linked imprinting (Skuse et al., 1997; Kesler et al., 2003). These factors (Murphy et al., 1993) may result in altered neurodevelopment and impaired cognitive ability.. Functional ...
TY - JOUR. T1 - Update on growth hormone therapy for Turners syndrome. AU - Rosenfeld, R. G.. PY - 1989/1/1. Y1 - 1989/1/1. UR - http://www.scopus.com/inward/record.url?scp=0024426424&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0024426424&partnerID=8YFLogxK. M3 - Article. C2 - 2683569. AN - SCOPUS:0024426424. VL - 78. SP - 103. EP - 108. JO - Acta Paediatrica Scandinavica, Supplement. JF - Acta Paediatrica Scandinavica, Supplement. SN - 0300-8843. IS - 356. ER - ...
... (TS) was first described in 1938 by Dr. Henry Turner, an endocrinologist, who noted a set of common physical features in some of his female patients. It is the result of a chromosomal abnormality in which a female infant is born with only one X chromosome (instead of two) or is missing part of one X chromosome.. In most cases, untreated females with this disorder are short in stature (average final adult height is 4 feet 7 inches) and may have a variety of related physical features and medical problems.. Because females with TS dont have proper ovarian development, they usually dont develop all of the secondary sexual characteristics (the physical changes or features that usually develop at puberty) during adolescence and are infertile (the inability to become pregnant) as adults. However, advances in medical technology, including hormonal therapy and in vitro fertilization, can help women with this condition.. Other health problems that may happen with TS include kidney and ...
CRESTVIEW - Turner Syndrome Family Fun Day is 11 a.m. to 3 p.m. Oct. 7 at the Fort Walton Beach Fairgrounds, 1958 Lewis Turner Blvd.Multiple bouncy houses for different age groups, laser tag, rock painting, vendor booths and fire truck tours are some of the days activities.Admission is free for children ages 2 and under, and $5 each for older children. Barbecue lunch plates will be served for $5 each as well. Other foods for sale include Boston butts, snow cones, cotton candy and
We compared arterial stiffness using CAVI between TS patients and healthy controls. When we included only TS patients without aortic disease, diabetes or HTN, and compared them to age- and BMI-matched healthy controls, TS patients showed significantly higher CAVI than healthy control subjects. After adjusting for age, TS was an independent risk factor for increased arterial stiffness.. In the present study, arterial stiffness measured by CAVI was increased in TS patients compared to control subjects matched for age and BMI. The stiffness of the arterial wall is highly relevant to cardiovascular disease. Arterial wall stiffness directly impacts the ability of the arteries to accommodate the blood ejected by the ventricles during each ejection and promotes increased target organ damage through excessive penetration of pulsatility into peripheral target organs [7]. Since TS patients in adulthood are at high risk for cardiovascular disease, a major cause of morbidity and mortality in TS [1], many ...
Pharmacotherapy of Turner syndrome (TS) is a hormonal therapy, which is used as an adjuvant treatment of Turner syndrome. At various ages, different medical problems are the focus of treatment. Short stature is diagnosed in the majority of TS patients. Without medical intervention, the final height is 20 cm below normal range. The growth-promoting therapy is based on the usage of growth hormone (GH) therapy. In some older patients (9 years) with very poor prognosis of final height, the addition of a low dose of oxandrolone (anabolic steroid) should be considered. The addition of oxandrolone to GH treatment may increase adult height by even more than 4 cm.. Another typical feature of TS patiens is gonadal dysgenesis (congenital developmental disorder of the reproductive system characterized by a progressive loss of germ cells on the developing gonads of an embryo) is diagnosed in most TS patients; however, more than 30 % of girls with TS present some symptoms of puberty, especially patients with ...
I dont see how a person with Turner Syndrome (45X)s sex is mixed, exactly. In my experiences with these girls, the second X seems kind of redundant, actually. lol They have all the female internal and external genitalia. Typically, they are often shorter than average and are often infertile due to premature ovarian failure. I was under the impression that you need to have a functioning Y chromosome to develop male anatomy. I guess I always sort of thought that TS girls are female sort of by default since they dont have an active Y chromosome. Having said that, I can see how having a mosaic karyotype of 45X, 46XY could have intersex anatomy, but I wouldnt consider any of the girls I have met with TS intersex at all. I personally feel that not all disorders of sexual development are intersex. Other than the missing X chromosome, what exactly is "intersex" about them? There are some girls with TS who have two X chromosomes with one of the chromosomes messed up somehow. If this is the case, how ...
I dont see how a person with Turner Syndrome (45X)s sex is mixed, exactly. In my experiences with these girls, the second X seems kind of redundant, actually. lol They have all the female internal and external genitalia. Typically, they are often shorter than average and are often infertile due to premature ovarian failure. I was under the impression that you need to have a functioning Y chromosome to develop male anatomy. I guess I always sort of thought that TS girls are female sort of by default since they dont have an active Y chromosome. Having said that, I can see how having a mosaic karyotype of 45X, 46XY could have intersex anatomy, but I wouldnt consider any of the girls I have met with TS intersex at all. I personally feel that not all disorders of sexual development are intersex. Other than the missing X chromosome, what exactly is "intersex" about them? There are some girls with TS who have two X chromosomes with one of the chromosomes messed up somehow. If this is the case, how ...
The SHOX gene is defined by The Free Dictionary as the following: Short stature homeobox gene or SHOX is a gene on the X chromosome and Y chromosome which is associated with short stature in humans if mutated or present in only one copy (haploinsufficiency). The gene was first found during a search for the cause of short stature in women with Turner syndrome, in which there is loss of genetic material from the X chromosome, sometimes by loss of one entire X chromosome. The SHOX gene is contained on the distal ends of the short arms of the X and Y chromosomes (pseudoautosomal part of the gene). The SHOX gene encodes a protein, which is a transcription factor. A transcription factor is a type of protein that enhances the expression of other genes involved in various developmental processes. This transcription factor contains a homeo domain, a special protein sequence that is able to bind to DNA and is involved in the regulation of multiple genes. Two active copies of the SHOX gene are needed for ...
Vicy married James B JB Turner, son of Jesse Turner and Gemima Mima Herald, about 29 Jun 1892. James was born on 25 Dec 1871 in Breathitt Co, KY, died on 18 Sep 1939 in Bach Memorial Hospital, Jackson, Breathitt Co, KY at age 67, and was buried on 20 Sep 1939 in J B Turner Cemetery, Buzzard Fork (Canoe) Breathitt Co, KY. Noted events in his life were: Cause of Death (Facts Pg): Labor pneumonia and chronic valular heart. Medical Information (Fact: Undertaker: Jesse E Turner of Canoe, Breathitt Co, KY; Informant: J B Turner, Jr of Canoe, Breathitt Co, KY; Doctor: G V Turner, MD of Jackson, KY. Occupation: Farmer. (Duplicate Line. See Person 169) 209. Sarah Arrowood was born on 24 Jun 1874 in Canoe, Breathitt Co, KY, died on 13 Aug 1932 in Hazel Green, Wolfe Co, KY at age 58, and was buried on 14 Aug 1932 in Arrowood Cemetery On Canoe Rd, Canoe, Breathitt County, KY ...
Turner recorded his fifth studio album in Burbank, California, in October 2012. The reason for recording abroad the first time in California was that producer Rich Costey wouldnt come to England with all his equipment so he convinced Turner to record it in Burbank.[9] Turner announced via Twitter on 28 October 2012 that recording was completed, and mixing and mastering would be done in time for a March 2013 release date. During the November and December UK tour a free CD titled Good Hangs from Xtra Mile Recordings was distributed for free at Turner shows, this included a yet-to-be-released Turner song titled "Tattoos" plus the Möngöl Hörde song "Casual Threats From Weekend Hardmen". On Christmas Day 2012, the song "Four Simple Words" was released on Xtra Mile Recordings website as a free download along with the b-side "Cowboy Chords". On 4 January 2013, a video was shot for what would be the first single. On the same day Turner announced on Twitter that the single was the song "Recovery". ...
Turner syndrome is a congenital complete or partial lack one of the female sex chromosomes affecting 1 of 2000 live born girls. The syndrome is characterized by an increased prevalence of ischemic heart disease, aortic dilation and dissection, congenital heart defects, hypertension, stroke, ovarian failure, infertility, decreased final height and autoimmune diseases in general. Our study aim is:. ...
1) Short stature. 2) Web neck ( Extra folds of skin on the neck). 3) Low hairline at the back of the neck. 4) Low-set ears. 5) Infections of the middle ear (otitis media) usually in infants. There is a documented relationship between Turner syndrome and sensorineural hearing loss in adults.. 6) Puffiness or swelling (lymphedema) of the neck, hands and feet.. 7) Broad shield shaped thorax and widely spaced nipples.. 8) Poor breast development. 9) Skeletal abnormalities including cubitus valgus (elbow deformity), scoliosis, short 4th metacarpal. 10) Narrow fingernails and toenails that are turned upward.. 11) Primary amenorrhea.. 12) Infantile external genitalia. 13) Ovaries severely atrophied and fibrous (streak ovaries). 14) Congenital heart disease, particularly aortic coarctation (narrowing of the large artery). 15) The incidence of aortic dissection is extremely common and occurs early in life and in pregnancy. 16) Skin changes, including an increased number of melanocytic nevi, hypertrophic ...
Learn about Turner syndrome, an abnormality in the X chromosome of females that leaves them infertile. Symptoms also include a webbed neck, puffiness of the hands and feet, heart defects, and kidney problems. Facts about causes, diagnosis and treatments
Turner syndrome is a genetic disorder that affects about 1 in every 2,500 girls. Learn more about the condition and how doctors treat it.
Turner syndrome is a genetic disorder that affects about 1 in every 2,500 girls. Learn more about the condition and how doctors treat it.
Free Online Library: Q&A : ADVICE FROM EXPERTS HORMONES OFFER HOPE TO THOSE WITH TURNERS SYNDROME.(L.A. LIFE) by Daily News (Los Angeles, CA); News, opinion and commentary General interest
Chronic endocrine conditions like Turner Syndrome can be complex and challenging for patients to successfully manage - and especially when transitioning to a new health care team. Recognizing the need to improve this transition process and to enhance care coordination between practices, the Endocrine Society spearheaded an initiative to develop pediatric-to-adult transitions of care tools for a variety of endocrine conditions. Partnering with a broad coalition of stakeholder organizations, condition-specific working groups were established with experts in the field to evaluate gaps in care coordination and to begin addressing needs in these areas. The resulting toolkits provide a comprehensive approach to successfully managing transitions for patients with various endocrine conditions.. ...
Ear and hearing problems are frequent in women with Turner syndrome and have a negative effect on well-being and quality of life. Throughout life different periods of ear and hearing problems can be...
This case shows a septated cystic hygroma (arrowed on the images), usually associated with Turners syndrome (45 X0), later proven by amniocentesis. In this particular case, the fetus had subcutaneous edema. Fetal echo (not included here) was al...
Cassidy is a woman who has Turner Syndrome and autism, and she hopes to spread a message of positivity, despite challenges faced in her journey.
Learn more about Turner Syndrome at Doctors Hospital of Augusta DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Tavis: Back now with part two of our conversation with Kathleen Turner. Before we get back into her life and career, lets take a quick look now at some of the memorable roles and films from her outstanding career, beginning with that breakout role in the Hollywood classic, "Body Heat.". [Montage of clips from Kathleen Turners films]. Tavis: We spent a lot of time last night talking about "Body Heat." Still looks just as good, doesnt it?. Kathleen Turner: Well, I think it stands up, yeah.. Tavis: Yeah, I think it does too. So I promised last night that we were going to start with "Romancing the Stone.". Turner: Oh, yeah, I have to make a confession.. Tavis: Go ahead, make a confession, go.. Turner: Well, sometimes, actually, when Im kind of blue or something, I might slip that film in and watch a few minutes of it because it cheers me up.. Tavis: You know what? See, you took the words out of my mouth. I love that movie because it makes me smile. Theres some things that I pop in on any given ...
Turners syndrome, one of the most common sex chromosome abnormalities in females, is caused by loss of part or all of an X chromosome. We report a case of mosaic Turners syndrome, posted for elective cesarean delivery under low-dose sequential combined spinal epidural anesthesia. The unique features of this case were the combination of an anticipated difficult airway and both short stature and scoliosis in the lumbar region. A titrated combined spinal-epidural technique was performed in order to avoid hemodynamic instability, which could have been exacerbated in the presence of cardiovascular deformities that accompany this syndrome in many cases ...
Turners syndrome, one of the most common sex chromosome abnormalities in females, is caused by loss of part or all of an X chromosome. We report a case of mosaic Turners syndrome, posted for elective cesarean delivery under low-dose sequential combined spinal epidural anesthesia. The unique features of this case were the combination of an anticipated difficult airway and both short stature and scoliosis in the lumbar region. A titrated combined spinal-epidural technique was performed in order to avoid hemodynamic instability, which could have been exacerbated in the presence of cardiovascular deformities that accompany this syndrome in many cases ...