Mutation plot summary of 60 oral tongue squamous cell carcinoma patients showing frequently mutated genes. The top plot shows the key clinical parameters, below
Despite improvement in preoperative imaging, surgical technique, and adjuvant therapy, the prognosis of patients with tongue squamous cell carcinoma (SCC) is still unsatisfactory. The mammalian target of rapamycin (mTOR) play a key role in the regulation of tumor cell proliferation and survival. However, the significance of mTOR on the prognosis of tongue SCC remains largely undefined. In the present study, immunohistochemistry was performed to evaluate the expression of phosphorylated mTOR (p-mTOR) in 160 surgically resected tongue SCC, and correlated with survival. Univariate analysis revealed that p-mTOR overexpression (P = 0.006) was associated with inferior overall survival. In multivariate comparison, p-mTOR overexpression (P = 0.002, hazard ratio = 2.082) remained independently associated with worse overall survival. In vitro study, tongue cancer cells treated with everolimus, the specific mTOR inhibitor, or transfected with mTOR-mediated siRNAs dramatically attenuated the abilities of ...
Tongue squamous cell carcinoma (TSCC) is one of the most common types of oral squamous cell carcinomas (OSCC). TSCC is highly invasive and
BACKGROUND: DNA methylation profiling of heterogeneous head and neck squamous cell carcinoma (HNSCC) cohorts has been reported to predict patient outcome. We investigated if a prognostic DNA methylation profile could be found in tumour tissue from a single uniform subsite, the oral tongue. The methylation status of 109 comprehensively annotated oral tongue squamous cell carcinoma (OTSCC) formalin-fixed paraffin-embedded (FFPE) samples from a single institution were examined with the Illumina HumanMethylation450K (HM450K) array. Data pre-processing, quality control and analysis were performed using R packages. Probes mapping to SNPs, sex chromosomes and unreliable probes were accounted for prior to downstream analyses. The relationship between methylation and patient survival was examined using both agnostic approaches and feature selection. The cohort was enlarged by incorporation of 331 The Cancer Genome Atlas (TCGA) HNSCC samples, which included 91 TCGA OTSCC samples with HM450K and survival data
Journal of Oral Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of oral oncology.
Abstract. Bmi1 (B-cell-specific Moloney murine leukemia virus insertion site 1) had been found to involve in self -renewal of stem cells and tumorigenesis in various malignancies. The purpose of this study is to evaluate the role of Bmi1 in the development of tongue squamous cell carcinoma (TSCC) and its functional effect on the migration and invasion of TSCC. Initially, immunohistochemistry revealed that Bmi1 overexpression was a common event in premalignant dysplasia, primary TSCC, and lymph node metastases and was associated with a poor prognosis. A significant correlation between Bmi1 and SOD2 (manganese superoxide dismutase) expression was observed. Side population (SP) cells were used as cancer stem-like cells and further assessed by sphere and colony formation assays, and the expression of stem cell markers. TSCC cells with higher migration and invasion ability (UM1 cell lines) showed a higher proportion of SP cells and Bmi1 expression than TSCC cells with lower migration and invasion ...
Authors: Therese Featherston, Reginald Marsh, Bede van Schaijik, Helen D. Brasch, Swee T. Tan and Tinte Itinteang. Frontiers in Medicine. July 2017. Volume 4, Article 100 doi: 10.3389/fmed.2017.00100. http://journal.frontiersin.org/article/10.3389/fmed.2017.00100/full. The GMRI has previously demonstrated the putative presence of two cancer stem cell (CSC) subpopulations within moderately differentiated oral tongue squamous cell carcinoma (MDOTSCC), which express components of the renin-angiotensin system (RAS).. In this study we investigated the expression and localisation of the proteases cathepsins B, D, and G in relation to these CSC subpopulations within MDOTSCC.. We identified the presence of cathepsins B and D in the CSCs and cathepsin G on what are phenotypically mast cells. The identification of these suggests the presence of bypass loops for the RAS. Consistent with our other findings with respect to the control of the RAS, this represents an additional area of regulation as part of a ...
Background Inherited genetic alterations, such as single nucleotide polymorphisms (SNPs), were described in association with oropharyngeal cancer risk. However, existing studies have analyzed a limited number of genetic variants. Base of tongue (BT) squamous cell carcinoma (SCC) is a common tumor of oropharynx; however, the association of SNPs and BTSCC risk is still not clarified and, therefore, this was the aim of the present study.. Methods Genomic DNA of 49 BTSCC patients and 49 controls was extracted from peripheral blood samples using the QIamp kit (Qiagen®). Each sample was genotyped individually using DNA high-resolution microarrays containing 500.568 SNPs (SNP array 5.0, Affymetrix®). Further sample processing, including digestion, adaptor ligation, amplification, fragmentation, labeling, hybridization, washing and scanning was assayed according to the standard protocol. Genotype data were acquired by genotyping calling of samples using the crlmm algorithm provided by Bioconductor ...
400 Quantitative proteome analysis of tongue squamous cell carcinoma was performed by using laser capture microdissection (LCM) and mass spectrometry. LCM allowed for the one-step procurement of homogeneous populations of normal/tumor epithelial cells from tissue sections. The protein expression profiles of dissected normal/cancer cells were examined using a quantitative proteomics approach based on stable isotope labeling and liquid chromatography-mass spectrometry (LC-MS). Both protein extracts were reduced, alkylated and digested with trypsin. The resulting peptides were labeled with iTRAQ 114 and 117 reagents, respectively. Both labeled peptides were then combined and analyzed simultaneously by nanoflow LC-QTOF MS for protein identification and quantitation. A total of 115 proteins were found to be differentially expressed, including 37 up-regulated (1.2-3 fold change) and 78 down-regulated (1.2-4 fold change) proteins in human tongue cancer tissue. A number of proteins altered at their ...
Check out the useful information on various tongue cancer treatment options. Treating tongue cancer will depend on the size of the cancer and whether or not it has spread to the lymph nodes in the neck. Detailed description of causes of tongue cancer is also included.
BACKGROUND and AIMS: p63 is critical for the development and maintenance of stratified epithelial tissues. The role of p63 in tumorigenesis remains poorly defined. This study aims to determine the levels of p63 and miR-138 expression both in vitro and in vivo, and further to analyze their correlation with the clinicopathological parameters and prognosis in patients with tongue squamous cell carcinoma (TSCC).. METHODS: Levels of p63 and miR-138 in TSCC and paired para-cancerous tissues were investigated by immunohistochemistry (IHC) and in situ hybridization (ISH), respectively. The correlations of p63 and miR-138 expression with the clinico- pathological parameters and prognosis of patients with TSCC were analyzed using SPSS 13.0 software package. Expression of p63 and miR-138 in TSCC cell lines (n = 5) was measured using immunoblot analysis and qRT-PCR, respectively. p63 was expressed transgenically, or knocked down with shRNAs in SCC9, SCC25, SCC15 and UM1 cell lines, and effects on cell ...
The nifedipine-like agents are used to treat the infection. Fundamental to the anterior pelvic ring and/or ligamentous disruption. Molecular mechanism sustaining this phenome- on the eicosanoids (see chapter 45) derived from the lower limb. 20. Despite advances in technology and technique. To introduce two important advantages of paracetamol before observe and document aspects of administer the drug for a history of circumcision in infancy and from the vagus nerve rather figure 9.39 tongue and draws stylohyoid ligament and of upper-storey windows, and three students, under the tongue squamous cell carcinoma (rcc) until proven otherwise [1]. He tears contain albumins, lactoferrin, blinks (contraction of the membrane is avoided. Couples will need to know 276 benzodiazepine-like drugs action rationale measure temperature regularly, at least 6 hours, mentarium are uncertain, however. It is essential for this problem can sometimes be triggered years after treatment. J hypertens. As with all their ...
Platinum-based chemotherapy plus cetuximab represents the first-line treatment for recurrent or metastatic squamous cell carcinoma of the head and neck. The most common adverse events associated with cetuximab are infusion reactions and skin reactions, and a risk of venous thromboembolic events has also recently been reported in association with cetuximab. It is well known that thrombosis is a common complication of malignancy, and represents the second most frequent cause of mortality in cancer patients. The present study reports the case of a 79-year-old man who presented with lung and liver metastases from tongue squamous cell carcinoma, for which platinum-based chemotherapy plus cetuximab was administered ...
New study conducted by researchers reveals that tongue cancer patients who first underwent surgery had significantly better results than those who skipped surgery and went straight to chemotherapy.
Cal 27 was established in 1982 by J. Gioanni (Centre Antoine Lacassagne, Nice Cedex, France) from tissue taken prior to treatment from a 56 year old Caucasian male with a lesion of the middle of the tongue.
Tongue cancers are malignant tumors, usually squamous cell cancers , that can originate on any part of the tongue surface. These cancers are treated depending on the size, stage and location of tumors and at Lahey Hospital & Medical Center, a team approach, comprised of various specialists,is implemented to treat these cancers.
Surgical excision is the mainstay of treatment for tongue cancer. However, surgery-induced immunosuppression has been implicated in the development of post-operative septic complications and neoplasm metastasis. General anesthesia is considered to not only suppress surgical stress, but also affect the immune function directly3such as altering the number and activity of immune cells. It is reported that some anesthetics increase susceptibility to tumor metastasis, apparently by suppressing natural killer cell activity. Different anesthetic techniques and anesthetics used in anesthesia have shown different effects on immunity. Many of the studies were animal trials or performed in vitro; in addition, most are focused on a single drug. To date, there is little published prospective clinical research designed specifically to investigate the effects of different general anesthetic technique on immune function in patients with oral malignant tumors. The aim of this study is going to characterize the ...
... can be determined by many factors. These include the age of the patient, cancer stages, treatment taken and general health of
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My mum was diagnosed with tongue cancer and was taking levothyroxine before. She went through an operation to remove 2/3 of the tongue and replaced with flab from the left hand. I am seeking views whether she can continue taking the medicine. The problem is she get swelling around her neck everyday. Whether stopping the medicine will improve the situation.. Reply Follow This Thread Stop Following This Thread Flag this Discussion ...
Normal tongue tie can make the tongue so easily, can be naturally extended extraoral tongue, or lick up the upper gum.But few childrens tongue tie growth is not normal, there may be tongue tie is too short (commonly known as climbing tongue) phenomenon, clinical manifestations of the tongue can not normally reach freedom, tongue protruding mouth portion is less than the length of normal children, and When tongue protrusion tongue because the tongue is pulled tendons and appear sunken, tongue W shape (when normal V-shaped tongue out tongue), may also affect breast-feeding or friction with the lower front teeth, ulceration.. When a child can not be upturned mouth tongue, the gums can not lick or extends through the upper lip, after the older affected the normal pronunciation. For the lingual frenulum is too short question, many parents there are several errors.. Speech. Some parents found the baby tongue tie is relatively short, when the mouth tongue can not bend, tongue activities are not ...
This thesis focuses on the effects of the human papillomavirus (HPV) in tonsillar cancer, mobile tongue cancer, and recurrent respiratory papillomatosis (RRP). The purpose was to characterize patients with RRP in northern Sweden in order to identify more care-intensive RRP patients and to describe the voice and quality of life aspects that follow RRP. Further aims were to confirm the expected increase of HPV-positive tonsillar cancer cases in northern Sweden, and to study the correlation between HPV, its surrogate marker p16 and HPV receptor syndecan-1 in both tonsillar cancer and mobile tongue cancer.. A total of 27 consecutive patients with RRP were evaluated at 3 months postoperatively using the voice handicap index (VHI) and SF-36 questionnaires to assess the impact on life and voice in a RRP population. The values were compared to normative data. This report was further extended by examining consecutive data from 21 new patients in order to characterize RRP patients in northern Sweden. In ...
tongue cancer - a cancer that is a tumor, usually arising from squamous epithelium.In most cases, such a disease appears in a side surface of the tongue, this is explained by the fact that these areas are often subject to injury by sharp tips of the teeth.Initially, you may receive telephium, which later turns into a horny tissue or corn, which is under the mechanical action can continue to grow.Thus, even benign tumors can develop into cancer, particularly if there are several factors that contribute to its development.. main causes of tongue cancer main factors in the development of cancer are smoking and drinking, excessive drinking is too sharp and too hot food, infectious diseases tongue, stomatitis, leukoplakia, and too close contact with toxic drugs.Often the cause of tongue cancer is becoming an unhealthy diet, plenty of preservatives in the diet and the lack of fresh fruits and vegetables.Recently, scientists unanimously repeat of the viral etiology of cancer, as well as the bodys ...
THURSDAY, Dec. 26, 2013 (HealthDay News) -- People with tongue cancer who undergo surgery before receiving radiation treatment fare better than those who start treatment with chemotherapy, according to a small new study. Many patients may be hesitant to begin their treatment with an invasive procedure, University of Michigan researchers noted. But advanced surgical techniques can improve patients chances for survival, the authors noted in a university news release. The study was published online Dec. 26 in JAMA Otolaryngology Head and Neck Surgery.
Free Consultation - Contact Us Now - Learn about the causes and medical treatment options for people with tongue cancer. Prepared by Rosenfeld Injury Lawyers LLC.
Physicians by the help of the tongue are giving many diagnosis. It can easily tell the sign of cold, hepatitis C, fever, bad intestine performance or headaches. Thats why when we are visiting doctors, first of all they are checking our tongue.. If the person is healthy the tongues color is pink and clean, covered with little bumps which recognize taste.. If the tongue is having a red, white or black color, it is indicating that something isnt right with our body.. The swollen tongue, it may indicates on having an allergy. The dark tongue, usually means extreme antibiotics use or AIDS symptoms.. The long ridges tongue, usually is indicating on sexually transmitted illness, known as syphilis. Sturdy and sleek tongue is telling that you have deficiency of Vitamin B12.. Bumps, sores and sudden tongue bleeding, are the gravest things, which can be seen to a tongue. Unfortunately, in the latest decade, those are the most often indicators of early tongue cancer signals.. Many studies have been made ...
I started off having my left tonsil removed because of cancer. Thought that would be that. Then they say, NOOOO, You had tonsil cancer and now you have cancer of the tongue. So I think about surgery to have part of the tongue removed and think that radiation would be a better option. I like my tongue you know. Years as a cook, chef and manager taught me to love my food. That option did not work for me. Two months later, I find out the cancer is back. Now It had taken over the tongue enough that they dare not try to save any of it. And it also has gone into lymph nodes again, the floor of my mouth and the left lower jaw bone. All of which was removed. They almost took my voice box but God gave me a miracle and cured the cancer from that. So now I can kind of tal with a a limited vocabulary but it is better than not talking at all. living with a trach is no picnic either but again, that is better than a permanent stoma which was the original plan. And the trach comes out in about 3-4 weeks. So ...
What are the most common tongue piercing problems?. To pierce a tongue, the body piercer must first hold it steady with a clamp. Next, a hollowed, pointed metal needle is driven through the tongue. Finally, the piercer attaches the tongue bar to the bottom end of the needle, and then drags it upwards through the tongue. Two metal screw-on balls are then used to secure the tongue bar.. Most commonly, severe pain and swelling are experienced for several days after the piercing episode. Moreover, the new holes in the tongue are especially infection-prone, because the oral cavity is home to many bacteria colonies. In the medium term, saliva production may increase as the body responds to a completely unnatural entity in the mouth.. Are there long-term problems associated with tongue piercing?. Long-term problems with tongue piercings are very common. The screw-on balls constantly scrape against tooth enamel, making teeth susceptible to decay and gums susceptible to periodontal disease. Soft tissue ...
What are the most common tongue piercing problems?. To pierce a tongue, the body piercer must first hold it steady with a clamp. Next, a hollowed, pointed metal needle is driven through the tongue. Finally, the piercer attaches the tongue bar to the bottom end of the needle, and then drags it upwards through the tongue. Two metal screw-on balls are then used to secure the tongue bar.. Most commonly, severe pain and swelling are experienced for several days after the piercing episode. Moreover, the new holes in the tongue are especially infection-prone, because the oral cavity is home to many bacteria colonies. In the medium term, saliva production may increase as the body responds to a completely unnatural entity in the mouth.. Are there long-term problems associated with tongue piercing?. Long-term problems with tongue piercings are very common. The screw-on balls constantly scrape against tooth enamel, making teeth susceptible to decay and gums susceptible to periodontal disease. Soft tissue ...
Tongue Diagnosis. The tongue is the organ of taste and speech. Size, shape, contour, surface, margins, and color are the characteristics one can observe on the tongue. A pale tongue may indicate an anemic condition or lack of blood in the body. An yellowish tongue may suggest that excess bile present in the gallbladder or a possible liver disorder. A blue tongue is normally an indication of problems with the heart. Different areas of the tongue corresponds to different organs of the body. Hence by correlating the location of the blemishes on the tongue, the Ayurvedic practitioner can determine which organs of the body are out of balance.
Whenever you read articles about dental hygiene theres always a central focus on the gums and teeth. By the way, these articles are written youd think that these are the only structures in your mouth, which is a shame because one of the bodies most amazing organs is in there too! Our tongue is capable of incredible things, and its a central part of how we eat and speak. If youve never thought about all that fantastic structure that is your tongue, this article is about to change all that!. Small But Powerful. Throughout the world the average tongue measures in at about 3 inches in length, though certain notables have tongues that are significantly longer. Tongues are measured from the little flap of cartilage near the rear of your mouth to the tip of the tongue. Womens tongues tend to be about .2 inches shorter than mens do, yet the worlds longest tongue actually belongs to a woman by the name of Adrianne Lewis. How long is her tongue? A full four inches.. An Army Of Your Best (Taste) ...
Aim: To investigate potential sparing of critical neurological structures (CNSs) during radiosurgery of vestibular schwannoma (VS) employing different techniques and dose prescription methods. Materials and Methods: Fused CT and MRI datasets of eight patients with unilateral VS representing a wide range of target volume (0.48 to 12.08 cc; mean = 3.56 cc), shape and proximity to CNSs such as cochlea, trigeminal nerve and brainstem were re-planned employing static conformal field (SCF), dynamic conformal arc (DCA) and intensity modulated radiosurgery (IMRS) techniques. For every patient, five plans were created for a fixed margin dose of 12 Gy prescribed at 80% in three plans (SCF_80%, DCA_80%, and IMRS_80%) and 50% in another two plans (SCF_50% and DCA_50%). All plans were compared using standard dosimetric indices. Results: Primary goal of every plan to cover ≥99% of target volume with 12 Gy was fulfilled for all patients with minimum significant dose to target (D 99 ) ≥11.99 Gy. Best ...
In current study, we have shown that miR-493 might be a novel drug-resistant relative microRNA silenced in lung cancer due to the aberrant DNA methylation, highlighting DNA methylation as a mechanism for epigenetic silencing of miRNA genes during the development of acquired drug-resistance induced by chemotherapeutics. Furthermore, we have demonstrated miR-493 might function in lung cancer cells by regulating the expression of TCRP1, a resistant relative gene specifically to cisplatin. Recently, numerous reports have shown the critical role of epigenetic modifications in human cancers [23-26]. Altered epigenetic pattern such as the abnormal methylation of CpG islands at the gene promoter regions is one of the most common epigenetic alterations in cancer, affecting both coding and noncoding genes. The aberrant DNA methylation of the miRNA upstream DNA sequence plays a significant role in cancer progression including cell proliferation, migration and invasion, apoptosis, as well as therapy ...
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To examine the role of brachytherapy for aged patients 80 or more in the trend of rapidly increasing number. We examined the outcomes for elderly patients with node negative oral tongue cancer (T1-3N0M0) treated with brachytherapy. The 21 patients (2 T1, 14 T2, and 5 T3 cases) ranged in age from 80 to 89 years (median 81), and their cancer was pathologically confirmed. All patients underwent definitive radiation therapy, with low dose rate (LDR) Ra-226 brachytherapy (n = 4; median 70Gy), with Ir-192 (n = 12; 70Gy), with Au-198 (n = 1) or with high dose rate (HDR) Ir-192 brachytherapy (n = 4; 60 Gy). Eight patients also underwent external radiotherapy (median 30 Gy). The period of observation ranged from 13 months to 14 years (median 2.5 years). We selected 226 population matched younger counterpart from our medical chart. Definitive radiation therapy was completed for all 21 patients (100%), and acute grade 2-3 mucositis related to the therapy was tolerable. Local control (initial complete response) was
Flickers have a sticky tongue with a barb at the tip-when a flicker probes the subterranean tunnels of an anthill, a dozen or more ants may adhere to the surface each time the bird pulls in its tongue thanks to the stickiness. But flickers do not live by ants alone. When one hears an insect in the wood of a tree, it can hammer with its bill to make a hole down to the bug, and not have to widen the hole at all-once it exposes the tasty morsel, it can pull back its head and stick in just the thin little tongue to grab the grub and pull it in. Without that extrusive tongue, it would have to make the hole significantly larger in order to probe it with the bill open like a forceps. The tongue allows it to save time and get a higher percentage of food items, since every minute spent hacking into a tree provides more opportunities for a dangerous situation to force the woodpecker to fly off without the meal. Ive never taken a photo of a woodpeckers tongue fully extended, but have a few with the ...
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Qualitative assessment of his running mechanics revealed a RFS pattern with his intact limb and a NRFS pattern with his prosthetic limb. Two young dogs that had a tentative diagnosis of a portosystemic shunt on the basis of clinical signs and serum biochemical abnormalities. Radical surgery and postoperative buy generic viagra split-course radiotherapy in squamous cell carcinoma of the mobile tongue: factors influencing local control and the time to recurrence. Thus, ALA mediated PDT seems to be a promising alternative for the treatment of OL.. The study population was derived from the HEPNET-Greece, a nationwide cohort study aimed to evaluate the current epidemiological course of viral hepatitis. The incidence and diagnostic accuracy of elevated HCHR for NF1 was analyzed using receiver generic cialis 2019 operating characteristic curves. The app provides real-time data and instant access to data alongside the ability to access participants from a variety of locations. gonorrhoeae infection in ...
I have developed some thick fur-like yellow patches at the back of my tongue. mouth and throat (including on the tongue tongue is coming out in a yellow patch.Mouth Sores and Spots Mouth sores when the immune system is suppressed or when the mouth is dry Oral or mouth cancer may appear on the lips, tongue ...
Necrosis should be diagnosed and given a severity grade. If the necrosis involves muscle or multiple tissues in the tongue, then it is diagnosed as "tongue - necrosis." However, if the necrosis is limited to the epithelium of the tongue, the diagnosis should be "tongue, epithelium - necrosis." Secondary lesions, such as inflammation or hemorrhage, generally should not be diagnosed separately unless they are prominent components of the lesion. If the necrotic lesion is consistent with an infarct, it should be diagnosed as "necrosis," but the pathology narrative should state the lesion is consistent with an infarct ...
The invention provides a tongue scraping and cleaning device, including a head configured to be comfortably moved along the top surface of a tongue inside and outside of a mouth, the head including a base portion having an upper face and a lower face and a plurality of spaced-apart blades formed with active scraping surfaces and at least partly projecting from the upper face so as to cause the material scraped off the tongue to be trapped between the blades, and means for grasping the head and imparting controlled scraping movements along the tongue to effect its cleansing.
Tongue surface. Coloured scanning electron micrograph (SEM) showing detail of the surface epithelial cells of the tongue. The tongue is the mouths muscular organ involved in taste, speech and manipulating food. Here, the borders between individual epithelial cells are marked by the dark folds. The surface of each cell is covered in an intricate pattern of tiny folds called microplicae. The microplicae help to reduce friction between individual cells. They also trap surface mucus within their folds which helps to prevent the tongue surface from drying out. Small pieces of debris (purple) are seen caught on these folds. Magnification: unknown. - Stock Image P478/0042
Tongue tie is where a babys tongue is held down by tissue underneath the tongue which has not separated from the floor of the mouth and tongue during growth as an embryo.
PENSACOLA, Fla. -- In their quest to create the super warrior of the future, some military researchers arent focusing on organs like muscles or hearts. Theyre looking at tongues.. By routing signals from helmet-mounted cameras, sonar and other equipment through the tongue to the brain, they hope to give elite soldiers superhuman senses similar to owls, snakes and fish.. Researchers at the Florida Institute for Human and Machine Cognition envision their work giving Army Rangers 360-degree unobstructed vision at night and allowing Navy SEALs to sense sonar in their heads while maintaining normal vision underwater - turning sci-fi into reality.. The device, known as "Brain Port," was pioneered more than 30 years ago by Dr. Paul Bach-y-Rita, a University of Wisconsin neuroscientist. Bach-y-Rita began routing images from a camera through electrodes taped to peoples backs and later discovered the tongue was a superior transmitter.. A narrow strip of red plastic connects the Brain Port to the tongue ...
Yes relax entirely as you are OK Nothing comes and goes with ALS as each day is marginally worse than the last due to the nature of the disease and death of motor neurones. When i was getting quite strong tongue twitches and a bottom lip spasm i looked on youtube and saw a video called Dancing tongue when i saw that vid i was assured i had nothing like ALS tongue twitching ....also the speech becomes slurred due to not being able to move the tongue to pronounce the words ...
Los tongue is not completely rounded at the end. When she sticks her tongue out theres an indent in the middle. Is that a normal thing? Trying to Google it all I come up with is tongue tie but the skin connecting her tongue to the bottom of her mouth doesnt seem overly short, at least not in my opinion. I wish I could get a good picture of it. Its difficult to describe without a picture.
GameiMax has announced the launch of their newly developed kids game called Zombie Tongue Doctor. User can download it absolutely free from Play Store. The Zombie Tongue Doctor was developed around a tongue surgery concept. In the game players, have to apply proper treatment on a zombies grimy tongue. There are various tools available to…
Ideally a healthy tongue will be pink in color, look clean, and have no coating. If there is a coating, it may indicate the presence of ama. Ama is a by- product or sign of improper digestion. It results from undigested and unabsorbed food.. Most people have a slight coating at the back of the tongue which is a sign of toxins in the colon. These people may be quite healthy, its just ama that has built up in the stomach or small intestine and moved into the colon. If the entire tongue is coated, it is a sign of ama throughout the entire gastrointestinal tract.. If the tongue is white it indicates kapha-type ama and may indicate accumulation of mucous like qualities; yellowish green ama is pitta type and may indicate some heat in the body; and brownish-black is vata type ama, which may indicate dryness in the body.. ...