In this paper, we present a graph-based multi-resolution approach for mitosis extraction in breast cancer histological whole slide images. The proposed segmentation uses a multiresolution approach which reproduces the slide examination done by a pathologist. Each resolution level is analyzed with a focus of attention resulting from a coarser resolution level analysis. At each resolution level, a spatial refinement by semi-supervised clustering is performed to obtain more accurate segmentation around edges. The proposed segmentation is fully unsupervised by using domain specific knowledge.
It is estimated that more than 19,000 pathologists would be needed to serve the US healthcare needs. However, the actual number is expected to be approximately 40% lesser. Similar trends are foreseen globally driven by aging population and widening application in areas such as cancer diagnostics, drug development, clinical trials, biomarker discovery, and companion diagnostics. Digital pathology can improve efficiency of pathologists by 10-15%, thereby helping the healthcare providers in filling such gaps. This factor is a key driver for the rapid growth in adoption of digital pathology solutions globally. In April 2017, FDA approved the IntelliSite Pathology Solution from Royal Philips. This was the first digital pathology product for which any US manufacturer received approval for primary diagnostics purpose. An expected increase in regulatory approval for digital pathology systems for primary diagnostics will support the growth in demand for these systems. To cater to the growing demand for digital
AccelPath, Inc. a provider of digital telepathology services, has announced that it has acquired privately held DigiPath Solutions, LLC a leading provider of digital telepathology and laboratory development and management services in Texas.
The digital pathology market is likely to experience an exponential growth by the end of the decade, especially in the regions, such as North America and Europe, where pathologists and medical laboratories are increasingly inclining towards the adoption of these systems. Cloud or Storage as a Service (SaaS) technology-enabled digital pathology is accompanied by key benefits, such as improved connectivity and efficiency, increased productivity, and cost reduction. Incorporation of digital pathology solutions enables accurate, high through put analysis and interpretation of histological images through the use of computer-assisted image analytics, which negate observer variability.. In addition, these technological solutions provide virtual, secure storage options with multi-tenant access to the digital slides. Cloud technology is further facilitating distance consultations between pathologists and physicians globally through the seamless integration of tools, which allow effective information ...
Journal publishes broadly about pathology informatics and aims to reach out to pathologists, informaticians, academics, researchers, health IT specialists, information officers and authors with an interest in informatics
Journal of Pathology Informatics, Journal of Pathology Informatics is official publications of The Association for Pathology Informatics
The 2012 conference presentations and PDFs are now available on-line. Click on the presentation titles in the 2012 schedule or View PDF links on the Scientific Session pages ...
The U.S. Food and Drug Administration (FDA) has permitted marketing of the Philips IntelliSite Pathology Solution (PIPS, Philips Medical Systems Nederland B.V.), as an aid to pathologists to review and interpret digital images of surgical pathology slides prepared from formalin-fixed paraffin embedded tissue.. PIPS is an automated digital slide creation, viewing, and management system that will allow pathologists to review and interpret digital images of surgical pathology slides prepared from formalin-fixed paraffin embedded tissue, rather than having to look directly under a conventional light microscope at a tissue sample mounted on a glass slide. This is the first FDA-authorized digital pathology whole-slide imaging system available for these purposes.. The FDA reviewed the data for the PIPS through the de novo premarket review pathway to provide a reasonable assurance of safety and effectiveness of the device. During this process, the FDA evaluated data from a multisite, multireader, ...
The rise of digital pathology and with it the challenges of histopathology analysis have been the focus of a worldwide effort in the overall fight against cancer. In parallel, the recent success of automated decision-making, machine learning, and specifically deep learning, have revolutionised the basis of research as we know today. In this thesis, we tackle the prediction of treatment response in triple-negative breast cancer patients with two different approaches that reach similar outcomes. The first line of approach, based on the recent success of computer vision, extracts learned features from the data in order to perform classification. The second line of approach forces the information flow to pass through nuclei segmentation. In particular, it allows the incorporation of high-resolution information on to a lower resolution overview. Yet while this approach is more appealing as it is based on the analysis and quantification of a precise biological element, nuclei segmentation is troublesome.
... TUCSON Ariz. June 3 2013 /- ...(Photo: h... This agreement represents a fusion of digital pathology visualizat...A turnkey digital pathology imaging solution ...,Ventana,and,Barco,revolutionize,digital,pathology,viewing,experience,medicine,advanced medical technology,medical laboratory technology,medical device technology,latest medical technology,Health
Digital Pathology Market Fortune Business Insights presents an in-depth analysis of the Digital Pathology Market size, growth, share, and technologies
While brightfield images (e.g. stained in H&E) are the primary choice for observing the morphology of the tissue, fluorescence images are better for the visualization of the cellular characteristics. Digital multiplexing of brightfield and fluorescence images can combine the benefits of both worlds while maintaining the individual characteristics of each of the modalities. Many digital pathology scanners available today are equipped to scan images in both brightfield and fluorescence mode. When using both modes for a tissue sample, adjoined sections are typically prepared and scanned separately and the resulting whole slide images (WSIs) need to be reviewed or analyzed individually. Aligning images from multiple modalities can help aggregating information from consecutive sections stained in histochemical and fluorescent dyes, e.g. protein expression and gene amplification by aligning immunohistochemical (IHC) markers with fluorescence in-situ hybridization (FISH). The aligned images can then be ...
Note: This is a Medical Student Elective Rotation in Pathology - available starting July 2010. Pathology Informatics uses data management, imaging and information theory to facilitate the diagnostic, research, and patient care missions of Pathology. This course will introduce students to the challenges and accomplishments in Pathology Informatics, while simultaneously providing integrated exposure to several subspecialty areas within the pathology department (i.e. surgical pathology, molecular pathology, cytopathology, laboratory medicine, etc.). Didactic sessions and hands-on laboratory experience form the core of the rotation. The student will also have the opportunity to work closely with faculty, fellows, and residents on a project of mutual interest. At the end of the clerkship, the student will present to the department on a topic of his or her choice.. While the course is primarily organized to provide preparation for a potential career in Pathology, students interested in other areas of ...
Note: This is a Medical Student Elective Rotation in Pathology - available starting July 2010. Pathology Informatics uses data management, imaging and information theory to facilitate the diagnostic, research, and patient care missions of Pathology. This course will introduce students to the challenges and accomplishments in Pathology Informatics, while simultaneously providing integrated exposure to several subspecialty areas within the pathology department (i.e. surgical pathology, molecular pathology, cytopathology, laboratory medicine, etc.). Didactic sessions and hands-on laboratory experience form the core of the rotation. The student will also have the opportunity to work closely with faculty, fellows, and residents on a project of mutual interest. At the end of the clerkship, the student will present to the department on a topic of his or her choice.. While the course is primarily organized to provide preparation for a potential career in Pathology, students interested in other areas of ...
Telepathology:. Evans AJ, Chetty R, Clarke BA, Croul S, Ghazarian DM, Kiehl TR, Perez-Ordonez, Ilaalagan S, Asa SL. Primary frozen section diagnosis by robotic microscopy and virtual slide telepathology: The University Health Network Experience. Hum Pathol, 40 (8):1070-1081, August 2009 (Special section on telepathology- Dr. R. Weinstein ed).. Evans AJ, Kiehl TR, Croul S. Frequently asked questions concerning the use of whole-slide imaging telepathology for neuropathology frozen sections. Sem Diag Pathol, 27(3):160-166, 2010.. Translational Research in Kidney and Prostate Cancer:. Evans AJ, Russell RC, Roche O, Burry TN, Fish JE, Chow VWK, Kim WY, Saravanan A, Maynard MA, Gervais ML, Sufan RI, Roberts AM, Wilson LA, Betten M, Vandewalle C, Berx G, Marsden P, Irwin MS, Teh BT, Jewett MAS, Ohh M. VHL promotes E2 Box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and Snail. Mol Cell Biol, 27 (1):157-169, 2007. Youssef Y, White NMA, Grigull J, Krizova A, Samy C, Meja-Guerrera, ...
Whole slide imaging in pathology: advantages, limitations, and emerging perspectives Navid Farahani,1 Anil V Parwani,2 Liron Pantanowitz2 1Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 2Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Abstract: Significant technologic gains have led to the adoption of innovative digital imaging solutions in pathology. Whole slide imaging (WSI), which refers to scanning of conventional glass slides in order to produce digital slides, is the most recent imaging modality being employed by pathology departments worldwide. WSI continues to gain traction among pathologists for diagnostic, educational, and research purposes. This article provides a technologic review of WSI platforms and covers clinical and nonclinical pathology applications of these imaging systems. Barriers to adoption of WSI include limiting technology, image quality, problems with scanning all materials (eg,
Results Digitally, 93/96 cases could be assessed (96.8%). Microscopic and digital evaluation of HER2 amplification status were concordant in 68/93 cases ((73.1%, 95% CI: 0.639 −0.823), κ 0.588). CISH underscoring was most noticeable in the amplified and equivocal categories while the highest level concordance was seen in cases with a normal copy number. Additionally there was a noticeable tendency to underestimate the average HER2 scores on WSI: lower in 59 and higher in 11 cases. There was no major difference in time spent for microscopic scoring (86.9 s) and digital scoring (81.7 s). ...
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This report includes forecasted trends and sales in the digital pathology and telepathology markets through 2020. Key market participants, extensive product segments, supporting technologies, trends and market dynamics, competitive intelligence and regional trends are discussed. There is a detailed discussion on market dynamics and the level of impact, key geographies and respective trends and competitive scenarios that will form the base data for qualitative analysis and market estimates. The digital pathology and telepathology market has been analyzed for the four main geographic regions: North America, Europe, Asia and the rest of the world (ROW). The report will provide details with respect to the conventional process of pathology laboratories, but it will specifically exclude the scope of market analysis for conventional path-lab devices (e.g., conventional microscopes, slides). The connectivity and network issues discussed in the report will be specific to data and information generated ...
University Hospital Network is the leader in providing remote coverage of frozen section procedures via telepathology and WSI technology. This allowed ability of right subspecialist pathologist to provide pathology interpretation on procedures regardless of its location. For the last two years, UHN is one of the first hospitals in the world that applied digital pathology to enable primary diagnosis for cases from Oshawa, 60km from Toronto General without the need of pathologists to travel to the site. About 15% of all cases from this site are scanned and transformed digitally to pathologists located at TGH, rest of the cases are still assembled with glass slides, packed and transferred via currier. UHN has demonstrated how the digital pathology technology can be utilized for patient care, and is poised to scale up the use of digital pathology for primary diagnosis. The current experience lead to identification of a number of areas that need to be addressed in order for UHN to fully benefit from ...
Image Analysis can be a powerful tool for researchers using digital pathology. We offer some top tips to consider when choosing your solution.
Digital pathology incorporates the acquisition, management, sharing and interpretation of pathology information - including slides and patient data - in a digital environment. Digital slides are created when glass slides are captured with a scanning device, to provide a high-resolution digital image that can be viewed on a computer screen or mobile device.
Timothy Baradet, PhD, HTL/QIHC (ASCP), Senior Research Investigator, Bristol-Myers Squibb. Tim received his Doctorate in Molecular Pathobiology from Drexel University College of Medicine, where he investigated mechanisms of amyloid deposition in Cerebrovascular Amyloid Angiopathy. He subsequently worked at the University of Pennsylvania where he managed combined histology and imaging core laboratories in the departments of Ophthalmology, Orthopedic Surgery, Gene Therapy, and Pathology as well as the first Digital Pathology Lab, utilizing whole-slide scans, highly multiplexed IHC and multi-spectral image analysis in support of the Pathology Test Development Center & Tumor Biospecimen Bank. Tim subsequently joined PathXL (now part of Philips Digital Pathology) as an Application Scientist, supporting image analysis & Digital Pathology workflow applications. He is currently a Senior Research Investigator at Bristol-Myers Squibb in the Translational Bioinformatics Group, providing Digital Pathology ...
At this years 29th Congress of the International Academy of Pathology (IAP 2012), Ventana Medical Systems, Inc. (Ventana), a member of the Roche Group, will unveil the latest versions of its Virtuoso digital pathology image and workflow management software and VANTAGE workflow solution for histology lab specimen tracking.
The author defines Digital pathology (which can also be referred to as virtual microscopy) as capturing, managing, analyzing and interpreting of digital information from a glass slide.
Eindhoven, the Netherland and Glostrup, Denmark - Royal Philips Electronics (NYSE: PHG, AEX: PHI) and Dako, yesterday announced that they have signed an agreement to integrate a selection of Dakos image analysis applications into Philips future digital pathology solutions. Anatomic pathology is an essential element
New agreement with Pathology-DNA, a collaboration between hospitals in Den Bosch, Nieuwegein and Arnhem in the Netherlands, underlines Philips leadership in digital pathology to support pathology departments enhance patient care and optimize efficiency.
Udine, 9 novembre 2018, Auditorium "A. Comelli" Regione Autonoma Friuli Venezia Giulia Via Sabbadini, 31 - Udine. Liniziativa si inserisce nel percorso di promozione dellutilizzo dellinnovazione tecnologica nel sistema socio-sanitario, come enunciato nella "Carta di S. Vito al Tagliamento sulla promozione della Robotica e Domotica nel nuovo paradigma di integrazione tra Ospedale e Territorio" (17 novembre 2017). Il focus sarà rivolto ad esplorare le opportunità delle recenti acquisizioni della domotica e delle tecnologie dentro e fuori le strutture sanitarie, le abitazioni, gli ambienti di lavoro ed i mezzi di trasporto urbano ed extra-urbano.. Info e programma: … Continue Reading. ...
BEST, The Netherlands-Royal Philips (NYSE: PHG, AEX: PHIA) today announced that it has acquired the CE mark for diagnostic use of its Philips Digital Pathology Solution. European pathologists will now be able to use the full digital solution as an aid in diagnosis for routine pathology, such as primary diagnosis of oncology.
Digital pathology could have immediate implications for patient care as well: the digital workflow could eliminate issues with handling materials and could detect abnormalities as they occur. Digitization also means pathologists no longer have to worry about the risk of losing or damaging specimens.
Sectra (STO: SECT B) announces a new distribution agreement with Opta-Tech. Under the agreement, Opta-Tech will provide Sectras digital pathology solution to the Polish market.
Linköping, Sweden - International medical imaging IT company Sectra (Link) (STO: SECT B) has announced that its digital pathology solution now has an interface with Finalist LIMS (Laboratory Information Management System). The interface facilitates a more
WEST COAST DIGITAL PATHOLOGY SEMINARS May 13 & 15, 2009CONTACT INFORMATIONAperio [email protected] Aperio Aperio is the market leader in
Digital slide sets for BDS !! BDS !! Oral Pathology !! Digital slide sets for BDS contain all the subjects which are taught to the students during,
FISH digital microscopy. Technician studying FISH (Fluorescence In Situ Hybridization) images obtained using an Ikoniscope, a fully automated digital microscopy machine. FISH is a cytogenetic technique used to detect and localize the presence or absence of specific DNA (deoxyribonucleic acid) sequences on chromosomes. Here it is being used as part of a breast cancer screening process to determine the presence of HER-2 (Human Epidermal growth factor Receptor 2), a protein giving higher aggressiveness in breast cancers. - Stock Image C003/0175
Background: Accurate diagnosis of melanocytic lesions is challenging, even for expert pathologists. Nowadays, whole-slide imaging (WSI) is used for routine clinical pathology diagnosis in several laboratories. One of the limitations of WSI, as it is most often used, is the lack of a multiplanar focusing option. In this study, we aim to establish the diagnostic accuracy of WSI for melanocytic lesions and investigate the potential accuracy increase of z-stack scanning. Z-stack enables pathologists to use a software focus adjustment, comparable to the fine-focus knob of a conventional light microscope. Materials and Methods: Melanocytic lesions (n = 102) were selected from our pathology archives: 35 nevi, 5 spitzoid tumors of unknown malignant potential, and 62 malignant melanomas, including 10 nevoid melanomas. All slides were scanned at a magnification comparable to use of a x40 objective, in z-stack mode. A ground truth diagnosis was established on the glass slides by four academic ...
Comprehensive spatial assessment of hormone receptor immunohistochemistry staining in digital whole slide images of breast cancer requires accurate detection of positive nuclei within biologically relevant regions of interest. Herein, we propose a combination of automated region labeling at low resolution and subsequent detailed tissue evaluation of subcellular structures in lobular structures adjacent to breast cancer, as a proof of concept for the approach to analyze estrogen and progesterone receptor expression in the spatial context of surrounding tissue. Routinely processed paraffin sections of hormone receptor-negative ductal invasive breast cancer were stained for estrogen and progesterone receptor by immunohistochemistry. Digital whole slides were analyzed using commercially available image analysis software for advanced object-based analysis, applying textural, relational, and geometrical features. Mammary gland lobules were targeted as regions of interest for analysis at subcellular level in
Jules Berman received two baccalaureate degrees from MIT; in Mathematics, and in Earth and Planetary Sciences. He received the Ph.D. from Temple University, and the M.D. from the U. of Miami. He received post-doctoral training at NIH and residency training at Geo. Washington U Med Ctr. He is board certified in anatomic pathology and in cytopathology. He served as Chief of Anatomic Pathology, Surgical Pathology and Cytopathology at the Veterans Administration Medical Center in Baltimore, Maryland, where he held joint appointments at the University of Maryland Medical Center and the Johns Hopkins Medical Institutions. In 1998, he became a Medical Officer at the U.S. National Cancer Institute and served as the Program Director for Pathology Informatics in the Institutes Cancer Diagnosis Program. In 2006, Jules Berman was President of the Association for Pathology Informatics. In 2011 he received the Lifetime Achievement Award from the Association for Pathology Informatics. Today, Jules Berman is a ...
Jules Berman received two baccalaureate degrees from MIT; in Mathematics, and in Earth and Planetary Sciences. He received the Ph.D. from Temple University, and the M.D. from the U. of Miami. He received post-doctoral training at NIH and residency training at Geo. Washington U Med Ctr. He is board certified in anatomic pathology and in cytopathology. He served as Chief of Anatomic Pathology, Surgical Pathology and Cytopathology at the Veterans Administration Medical Center in Baltimore, Maryland, where he held joint appointments at the University of Maryland Medical Center and the Johns Hopkins Medical Institutions. In 1998, he became a Medical Officer at the U.S. National Cancer Institute and served as the Program Director for Pathology Informatics in the Institutes Cancer Diagnosis Program. In 2006, Jules Berman was President of the Association for Pathology Informatics. In 2011 he received the Lifetime Achievement Award from the Association for Pathology Informatics. Today, Jules Berman is a ...
The major impetus for adopting Trestles Internet microscopy technology, according to Dynacare Kaspers president, Thomas Higa, MD, was to enable its clients in non-urban, less-populated regions to link to Dynacares eighteen pathologists in real-time consultation.. "When the Province of Alberta restructured the health care system", stated Dr. Higa, "it created a series of Regional Health Authorities, some of which were responsible for providing care to large geographic areas but often with only a couple of pathologists, and sometimes with none. Using Trestles solution, we can use real-time teleconsulting to share the expertise of our medical staff with doctors at any of our clients facilities.". The recent deployment of a Trestle MedMicro system at a Regional Health Authority site in the city of Fort McMurray demonstrated the value Trestles solution can provide for Dynacare Kasper. The city is experiencing rapid population growth due to its thriving oil business, but is geographically ...
Visual estimation of tumor and stroma proportions in microscopy images yields a strong, Tumor-(lymph)Node- Metastasis (TNM) classification-independent predictor for patient survival in colorectal cancer. Therefore, it is also a potent (contra)indicator for adjuvant chemotherapy. However, quantification of tumor and stroma through visual estimation is highly subject to intra- and inter-observer variability. The aim of this study is to develop and clinically validate a method for objective quantification of tumor and stroma in standard hematoxylin and eosin (H and E) stained microscopy slides of rectal carcinomas. A tissue segmentation algorithm, based on supervised machine learning and pixel classification, was developed, trained and validated using histological slides that were prepared from surgically excised rectal carcinomas in patients who had not received neoadjuvant chemotherapy and/or radiotherapy. Whole-slide scanning was performed at 20× magnification. A total of 40 images (4 million ...
Visual estimation of tumor and stroma proportions in microscopy images yields a strong, Tumor-(lymph)Node- Metastasis (TNM) classification-independent predictor for patient survival in colorectal cancer. Therefore, it is also a potent (contra)indicator for adjuvant chemotherapy. However, quantification of tumor and stroma through visual estimation is highly subject to intra- and inter-observer variability. The aim of this study is to develop and clinically validate a method for objective quantification of tumor and stroma in standard hematoxylin and eosin (H and E) stained microscopy slides of rectal carcinomas. A tissue segmentation algorithm, based on supervised machine learning and pixel classification, was developed, trained and validated using histological slides that were prepared from surgically excised rectal carcinomas in patients who had not received neoadjuvant chemotherapy and/or radiotherapy. Whole-slide scanning was performed at 20× magnification. A total of 40 images (4 million ...
Rizzardi AE, Johnson AT, Vogel RI, Pambuccian SE, Henriksen J, Skubitz AP, Metzger GJ, Schmechel SC.. Abstract: Immunohistochemical (IHC) assays performed on formalin-fixed paraffin-embedded (FFPE) tissue sections traditionally have been semi-quantified by pathologist visual scoring of staining. IHC is useful for validating biomarkers discovered through genomics methods as large clinical repositories of FFPE specimens support the construction of tissue microarrays (TMAs) for high throughput studies. Due to the ubiquitous availability of IHC techniques in clinical laboratories, validated IHC biomarkers may be translated readily into clinical use. However, the method of pathologist semi-quantification is costly, inherently subjective, and produces ordinal rather than continuous variable data. Computer-aided analysis of digitized whole slide images may overcome these limitations. Using TMAs representing 215 ovarian serous carcinoma specimens stained for S100A1, we assessed the degree to which data ...
Teleophthalmology is a branch of telemedicine that delivers eye care through digital medical equipment and telecommunications technology. Today, applications of teleophthalmology encompass access to eye specialists for patients in remote areas, ophthalmic disease screening, diagnosis and monitoring; as well as distant learning. Teleophthalmology enables health professionals to take ocular images and attend to patients who have limited access to ocular health care. These images allow the ophthalmologist or optometrist, health care professionals and researchers to carry out the aforementioned applications. The required equipment includes a camera that can take ocular images and a computer terminal with network capabilities, which can transfer the images. There has been a significant increase in teleophthalmology research over the past decade. However, differences in health information exchange standards, data security, liability issues, and cost of equipment are other major challenges in ...
The superficial dermis in each of the skin sections on this slide is expanded by similar, unencapsulated, well-demarcated, collagenous masses that elevate the epidermis and widely separate hair follicles and adnexal glands. A small number of small arthropods are attached to the surface of the haired skin adjacent to the masses, and the superficial dermis is infiltrated by moderate numbers of inflammatory cells. The fibrous connective tissue of both masses consists of a regular arrangement of interlacing bundles that separate a moderate number of uniformly dispersed fibrocytes or small fibroblasts. The deep margin of one masses is infiltrated by a band of lymphocytes with a few plasma cells and macrophages. The lymphocytes are scattered within the deep portions of the mass, but they do aggregate more densely around a few veins and small arteries. Inflammatory ifiltrates in the other mass are loosely aggregated in the deep portions of the nodule, but also infiltrate the superficial portions of the ...
Tsukuba Pathology Slide Seminar No.104 July 28, 1995 13:00-14:30 (AFIP WSC=14:30-17:00) Conference Room in NIAH main building , 2nd floor. 3-1-1, Kannondai, Tsukuba 305 Japan Following cases including clinical, epidemiological, gross and histopathological findings will be presented in the seminar. Cases: No.113: Rabbit viral hemorrhagic disease. (Dr. Itoh of Shizuoka prefecture) No.114: Interstitial pneumonia with fibrinous purulent pleuritis in pig. (Dr. Ono, JA Zen-noh Lab.) No.115: Chronic gastric ulcer and atrophic gastritis in man (Dr. Obana, Teijin) If you are ineresting in Pathology, Please join us! --------------------------------------------------- Name: Eiichi Momotani.DVM. PhD. Phone:0298-38-7781 Lab. of Immunopathology, NIAH,3-1-1 Kannondai,Tsukuba 305 Japan E-mail: momotani at niah.affrc.go.jp (for business!) NBA02413 at niftyserve.or.jp (for private or week end!) My WWW home page: http://ss.niah.affrc.go.jp/~momotani/ 07/10/95 21:53:39 --- PC9801Ap/MS-WINDOWS/Chameleon/X ...
Explore the basics of automated digital microscopy systems, including: a brief history of the microscope, the current state of the automated digital microscope, microscope objective types and automated XY stage motion and fluorescence imaging with Dover Motion.
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Congrats to Dr. Andrew Janowczyk, whose paper Deep learning for digital pathology image analysis: A comprehensive tutorial with selected use cases has been accepted for publication in the Journal of Pathology Informatics.. ...
Manual screening by light microscopy is the most widely used method for tubercle bacilli detection in the developing country. However, it is a time consuming and labour-intensive process. In this paper, a method using image processing technique and neural network classification has been proposed for automated tubercle bacilli detection in sputum slide images. The method mainly consists of three main stages: image segmentation, feature extraction and identification. Hybrid multilayered perceptron (HMLP) network using modified recursive prediction error training algorithm have been used to perform TB identification. Experimental results demonstrated that the HMLP network achieved the classification accuracy with percentage of 73.9 ...