Hybridization is a major driver of evolution in plants. In a number of plant species, the process of hybridization has been revealed to be accompanied by wide-ranging genetic and epigenetic alterations, some of which have consequences on gene transcripts. The Asteraceae family includes a number of polyploid species, and wide crossing is seen as a viable means of genetically improving ornamental species such as Chrysanthemum spp. However, the consequences of hybridization in this taxon have yet to be characterized. Amplified fragment length polymorphism (AFLP), methylation sensitive amplification polymorphism (MSAP) and cDNA-AFLP profiling of the two intergeneric hybrids C. nankingense × Tanacetum vulgare and C. crassum × Crossostephium chinense were employed to characterize, respectively, the genomic, epigenomic and transcriptomic changes induced by the hybridization event. The hybrids AFLP profiles included both the loss of specific parental fragments and the gain of fragments not present in either

Floral volatiles and reward traits are major drivers for the behavior of mutualistic as well as antagonistic flower visitors, i.e., pollinators and florivores. These floral traits differ tremendously between species, but intraspecific differences and their consequences on organism interactions remain largely unknown. Floral volatile compounds, such as terpenoids, function as cues to advertise rewards to pollinators, but should at the same time also repel florivores. The reward composition, e.g., protein and lipid contents in pollen, differs between individuals of distinct plant families. Whether the nutritional value of rewards within the same plant species is linked to their chemotypes, which differ in their pattern of specialized metabolites, has yet not been investigated. In the present study, we compared Tanacetum vulgare plants of five terpenoid chemotypes with regard to flower production, floral headspace volatiles, pollen macronutrient and terpenoid content, and floral attractiveness to

In vitro cytotoxicity of Tanacetum vulgare mediated silver nanoparticles against breast cancer (MCF-7) cell lines, Qipeng Liu, Hua Jiang

The aerial parts of Tanacetum argyrophyllum (C. Koch) Tvzel. var. argyrophyllum and T. parthenium (L.) Schultz Bip. were hydro-distilled to produce the oils in the yields of 0.78% (v/w) and 0.43% (v/w), respectively. The oils were analysed by GC and GC/MS. Twenty-two and twenty-three components were identified representing 94.2% and 90.1% of the oils, respectively. The main compounds of T. argyrophyllum were cis-thujone (69.9%), transthujone (5.6%) and 1,8-cineole (3.2%), whereas camphor (56.9%), camphene (12.7%) and p-cymene (5.2%) were the major constituents of T. parthenium. (c) 2005 Published by Elsevier Ltd. ...

1. Alaska Plant Management Team. 2005. Asteraceae species of greatest concern: Common tansy, [Online]. In: Invasive species in Alaska--species information. Anchorage, AK: U.S. Department of the Interior, National Park Service, Alaska Region (Producer). Available: http://www.nps.gov/akso/NatRes/EPMT/Species_bios/Tanacetum%20vulgare.pdf [2009, June 22]. [75612]. 2. Anderson, J. P. 1959. Flora of Alaska and adjacent parts of Canada. Ames, IA: Iowa State University Press. 543 p. [9928]. 3. Anzinger, Dawn; Radosevich, Steven R. 2008. Chapter 10: Fire and nonnative invasive plants in the Northwest Coastal bioregion. In: Zouhar, Kristin; Smith, Jane Kapler; Sutherland, Steve; Brooks, Matthew L., eds. Wildland fire in ecosystems: fire and nonnative invasive plants. Gen. Tech. Rep. RMRS-GTR-42-vol. 6. Ogden, UT: U.S. Department of Agriculture, Forest Service, Rocky Mountain Research Station: 197-224. [70906]. 4. Asher, Jerry; Dewey, Steven; Olivarez, Jim; Johnson, Curt. 1998. Minimizing weed spread ...

Dr. Jennifer Williamson, ND. Tansy (Tanacetum vulgare) is in the same Genus as some other medicinal plants, but each one of them has different uses. Blue Tansy is Tanacetum annuum and is used as an essential oil for its anti-inflammatory, anti-allergenic, calming and relaxing properties. Feverfew is Tanacetum parthenium and is most well known for preventing and treating migraines, but is otherwise just a great anti-inflammatory.. This one is just called Tansy and it is both edible and medicinal. Eating too much is not advised, but it can be dried and used as a spice. One source said that the young leaflets could be eaten raw or cooked, in small quantities. I no longer have young plants around, but I just chewed a leaf and flower from my backyard and I dont think it would be enjoyable raw. However, I imagine it would be enjoyable as a spice and I plan to go out later to harvest some for drying. It tastes somewhat earthy like sage, and pungent like clove.. Medicinally, Tansy kills ticks and ...

Tansy will produce a beautiful display of fine green leaves, and clusters of bright yellow button-like flowers. Available in 1 litre pots, buy online now.

This mixture of large, vibrant daisies will range from white, to pink, to red. The stunning blooms are perfect for cutting and will provide a cheery show in late spring to summer. (Pyrethrum or Tanacetum)

From the aerial parts of Tanacetum balsamita L. (Compositae) a flavonol aglycon was iso-lated using chromatographic techniques. The structure of this compound was determined using spectroscopic methods (UV, H-NMR and MS) as 3,4,5,7-Tetrahydroxy flavonol (Quercetin).

Tanacetum polycephalum (L.) Schultz-Bip (Mokhaleseh) has been traditionally used in the treatment of headaches, migraines, hyperlipidemia and diabetes. The present study aimed to evaluate its anticancer properties and possible mechanism of action using MCF7 as an in vitro model. T. polycephalum leaves were extracted using hexane, chloroform and methanol solvents and the cytotoxicity was evaluated using the MTT assay. Detection of the early apoptotic cells was investigated using acridine orange/propidium iodide staining. An Annexin-V-FITC assay was carried out to observe the phosphatidylserine externalization as a marker for apoptotic cells. High content screening was applied to analyze the cell membrane permeability, nuclear condensation, mitochondrial membrane potential (MMP) and cytochrome c release. Apoptosis was confirmed by using caspase-8, caspase-9 and DNA laddering assays. In addition, Bax/Bcl-2 expressions and cell cycle arrest also have been investigated. MTT assay revealed significant

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Tansy (Tanacetum vulgare) is a perennial, herbaceous flowering plant of the aster family, native to temperate Europe and Asia. It has been introduced to other parts of the world including North America, and in some areas has become invasive. It is also known as common tansy, bitter buttons, cow bitter, or golden buttons. Tansy is a flowering herbaceous plant with finely divided compound leaves and yellow, button-like flowers. It has a stout, somewhat reddish, erect stem, usually smooth, 50-150 cm (20-59 in) tall, and branching near the top. The leaves are alternate, 10-15 cm (3.9-5.9 in) long and are pinnately lobed, divided almost to the center into about seven pairs of segments, or lobes, which are again divided into smaller lobes having saw-toothed edges, giving the leaf a somewhat fernlike appearance. The roundish, flat-topped, button-like, yellow flower heads are produced in terminal clusters from mid-to-late summer. The scent is similar to that of camphor with hints of rosemary. The leaves ...

The European grapevine moth (EGVM), Lobesia botrana, is a major pest of grapes in Europe. Females are attracted to a nonhost plant: tansy (Tanacetum vulgare L.), which is a common weed in Slovakian vineyards. A steam distillate extract of tansy flowers was analyzed by means of a GC-EAG technique to screen constituents detected by the olfactory receptors of EGVM females. From more than 200 GC peaks, nine peaks corresponding to monoterpenoids released an EAG response in more than 70% of the females (N=15):p-cymene,d-limonene,α-thujene,α-thujone,β-thujone, thujyl alcohol, terpinene-4-ol, (Z)-verbenol, and piperitone. The steam distillate of tansy as well as a synthetic blend of identified compounds released consistent attraction in a field cage. The use of ...

TY - JOUR. T1 - Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes. AU - Goldenberg, Regina Coeli dos Santos. AU - Iacobas, Dumitru A.. AU - Iacobas, Sanda. AU - Rocha, Leonardo Lima. AU - da Silva de Azevedo Fortes, Fabio. AU - Vairo, Leandro. AU - Nagajyothi, Fnu. AU - Campos de Carvalho, Antonio Carlos. AU - Tanowitz, Herbert B.. AU - Spray, David C.. PY - 2009/12. Y1 - 2009/12. N2 - Trypanosoma cruzi infection is a major cause of cardiomyopathy. Previous gene profiling studies of infected mouse hearts have revealed prominent changes in gene expression within many functional pathways. This variety of transcriptomic changes in infected mice raises the question of whether gene expression alterations in whole hearts are due to changes in infected cardiac myocytes or other cells or even to systemic effects of the infection on the heart. We employed microarrays to examine infected cardiac myocyte cultures 48 h post-infection. Statistical comparison of gene expression levels ...

The old German name reynfan used by Hildegard refers to the effect of tansy (Tanacetum vulgare) on the reins, or kidneys. The fifteenth-century herbal??Der Gart der Gesundheit differs from Hildegard in classifying tansy as hot and dry in the first degree, rather than moist; it recommends tansy as a diuretic and vermifuge, as well as a treatment for gout and fever. (For more on Hildegard of Bingen, see Mutter Natur, October 15, 2010. For more on the humoral theory on which her prescription is based, see Cool, Cooler, Coolest, July 27, 2012.) Read more ». ...

Candida Formula #2™ (formerly Foon Goos #2®) Directions: Two capsules 3 times daily before meals. Ingredients: Tansy -------------------------------------------------------------------------------- Family: Compositae Latin Name: Tanacetum vulgare -------------------------------------------------------------------------------- Description Tall spreading stems with a height of 4 feet and a width of 2-3 feet. It has bright yellow, button-like flowers and feather, fern-like, multi-divided leaves. It is very pungent and blooms July to September. -------------------------------------------------------------------------------- Common Uses The constituent thujone kills intestinal roundworms and threadworms, scabies, and heals other infected skin conditions. Very small doses have been used to treat epilepsy and to encourage menstruation. Tansy has been used externally with benefit for some eruptive diseases of the skin, and the green leaves, when pounded and applied to skin,

Essential Oil of Tansy (Blue) (Tanacetum annuum). Family: Asteraceae. Origin: Morocco. Plant description: A flowering herbaceous plant with finely divided compound leaves and yellow, button-like flowers. Part of plant used for essential oil: Flowers. Extraction method: Steam distillation. Main Chemical Constituents: Thujone, isopinocamphone, camphor, borneol, camphone, artmisone, chamzaulene, limonene, and piperitone. PRECAUTIONS: Not to be confused with Tansy oil which is a potent poison due to high concentration of thujone. Blue Tansy has the potential to interact with certain OTC and prescription drugs. Avoid use with small children, elders, epileptics, pregnant and/or nursing women. Do not use higher than 5% in a dilution.. PROPERTIES: Anti-bacterial, anti-fungal, anti-inflammatory, anti-histaminic, antiviral, febrifuge, insecticide, hormone stimulant, sedative, and vermifuge substance.. USES:. Circulation/Muscles/Joints: Soothes inflammation and reduces pain. Immune System: Counteracts ...

Poustchi, F. and Amani, H. and Ahmadian, Z. and Niknezhad, S.V. and Mehrabi, S. and Santos, H.A. and Shahbazi, M.-A. (2021) Combination Therapy of Killing Diseases by Injectable Hydrogels: From Concept to Medical Applications. Advanced Healthcare Materials, 10 (3). Amani, H. and Shahbazi, M.-A. and DAmico, C. and Fontana, F. and Abbaszadeh, S. and Santos, H.A. (2021) Microneedles for painless transdermal immunotherapeutic applications. Journal of Controlled Release, 330. pp. 185-217. Amani, H. and Arzaghi, H. and Bayandori, M. and Dezfuli, A.S. and Pazoki-Toroudi, H. and Shafiee, A. and Moradi, L. (2019) Controlling Cell Behavior through the Design of Biomaterial Surfaces: A Focus on Surface Modification Techniques. Advanced Materials Interfaces. Amani, H. and Habibey, R. and Shokri, F. and Hajmiresmail, S.J. and Akhavan, O. and Mashaghi, A. and Pazoki-Toroudi, H. (2019) Selenium nanoparticles for targeted stroke therapy through modulation of inflammatory and metabolic signaling. Scientific ...

Genera In Family: +- 1500 genera, 23000 species: worldwide, many habitats. Note: Flower and head types differ in form and sexual condition. A disk flower has a generally radial corolla, with a cylindric tube, expanded throat, and generally 5 lobes. Disk flowers are generally bisexual and fertile but occasionally staminate with reduced ovaries. Discoid heads comprise only disk flowers. A radiant head is a variant of a discoid head, with peripheral disk flower corollas expanded, often bilateral. A ray flower corolla is bilateral, generally with a slender tube and flattened petal-like ray (single lip composed of generally 3 lobes). Ray flowers are generally pistillate or sterile (occasionally lacking styles). Radiate heads have peripheral ray flowers and central disk flowers. Disciform heads superficially resemble discoid heads, with pistillate or sterile flowers that lack rays, together with or separate from disk flowers. A ligulate flower is bisexual, with a bilateral, generally ephemeral corolla ...

Amani Research Centre is located at Ubwari in Muheza, north-eastern Tanzania at about 40 km west of Tanga City. Amani Medical Research centre was initially established at Ubwari, Muheza by Capt. Dr. Bagster Wilson in 1949 as the East African Malaria Unit (EAMU) under the British Colonial and Welfare Scheme. At that time, the unit served British Somaliland, Kenya, Uganda, Tanganyika, and Zanzibar in the control of malaria and other vector-borne diseases. In 1951, the Unit was moved to Amani and was renamed East African Malaria Institute and became operational under the East African High Commission in 1951. During this period research covered malaria, schistosomiasis and onchocerciasis. In addition the Institute had a strong training component targeting malaria field workers covering basic malariology and control of malaria vectors.. In 1954, the EAMI was renamed the East African Institute of Malaria and Vector Borne Diseases (EAIMVBD). While research on schistosomiasis was phased out in 1960, ...

Tansy was formerly used as a flavouring for puddings and omelettes, but this culinary use is now almost unknown. The herbalist John Gerard (c. 1545-1612) noted that tansy was well known as pleasant in taste, and he recommends tansy sweetmeats as an especial thing against the gout, if every day for a certain space a reasonable quantitie thereof be eaten fasting. In Yorkshire, tansy and caraway seeds were traditionally used in biscuits served at funerals. During the Restoration, a tansy was a sweet omelette flavoured with tansy juice. In the BBC documentary The Supersizers go ...Restoration, Allegra McEvedy described the flavour as fruity, with a sharpness to it and then theres a sort of explosion of cool heat a bit like peppermint. However, the programmes presenter Sue Perkins experienced tansy toxicity. According to liquor historian A. J. Baime, in the 19th century Tennessee whiskey magnate Jack Daniel enjoyed drinking his own whiskey with sugar and crushed tansy leaf. ...

Boasting a mixture of potent maritime ingredients, our Brightening Serum works wonders to even and brighten skin-tone as the lack of sunlight dulls our complexions. Starring: Blue Tansy (Tanacetum annuum) Also known as Moroccan chamomile, this blue-hued oil is an anti-inflammatory, soothing, and calming essential oil.

SHOCKING Review: Does Blue Tansy Essential Oil Work Or Scam? Is It Safe To Use? Read All About Blue Tansy Essential Oil Ingredients, Side Effects And More.

Tansy is a widely grown herb with a number of traditional medicinal uses, but needs to be used with an abundance of caution. Tansy was a popular strewing herb in times past because its clean, camphorous scent repelled flies and other pests. It is still

Hudson Mohawk Magazine 11-13-17 on WOOC 105.3 FM with Ellie Irons, Amani Oglubala, Iyad Burnat, Greg Francese and Jen Ceponis live from The Sanctuary for Independent Media in Troy NY.. 00:00 Ellie Irons; ...

PCRBIO Rapid Extract been developed fast efficient amplification from variety tissues particularly suited solid tissue such mouse tail mouse Sample processing simplified contamination risks minimised extraction performed single tube removing need multiple washing steps Extracted amplified proprietary buffer system using PCRBIO antibody-mediated start polymerase uses latest developments polymerase technology buffer chemistry enhance speed yield sensitivity Primer dimer formation non-specific amplification

Global transcriptomic alterations of both coding and non-coding RNA species are a ubiquitous feature associated with human cancers including hepatocellular carcinoma (HCC). Dysregulation of RNA-binding proteins (RBPs), the key regulators of RNA processing, is one mechanism in which cancer cells select to promote tumorigenesis. We analyzed genomic alterations amongst a family of more than 800 mRNA RBPs (mRBPs) in 1,225 clinical specimens from HCC patients and found that RBPs are significantly activated through gene amplification in a subset of tumors with poor prognosis, suggesting their potential oncogenic roles in HCC progression. Amongst the top candidates, RD binding protein (RDBP) was further characterized for its oncogenic role and effects on the HCC transcriptome. While the activation of RDBP induced an oncogenic phenotype, the abrogation of RDBP in HCC cells significantly decreased cancer associated phenotypes such as cell proliferation, migration/invasion and tumorigenicity in vivo. ...

Sárközy, Márta and Szűcs, Gergő and Fekete, Veronika and Pipicz, Márton and Éder, Katalin and Gáspár, Renáta and Sója, Andrea and Pipis, Judit and Ferdinandy, Péter and Csonka, Csaba and Csont, Tamás Bálint and Zvara, Ágnes and Szűcs, Csilla (2016) Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats. CARDIOVASCULAR DIABETOLOGY, 15 (1). p. 110. ISSN 1475-2840 Csont, Tamás and Murlasits, Zsolt and Ménesi, Dalma and Kelemen, János Z and Bencsik, Péter and Pipicz, Márton and Fekete, Veronika and Zvara, Ágnes and Puskás, László G and Ferdinandy, Péter (2015) Tissue-specific Gene Expression in Rat Hearts and Aortas in a Model of Vascular Nitrate Tolerance. Journal of cardiovascular pharmacology, 65 (5). pp. 485-93. ISSN 1533-4023 Buzás, Krisztina and Marton, Annamária and Vizler, Csaba and Sebestyén, Edina and Harmati, Mária and Nagy, Katalin and Zvara, Ágnes and Katona, Róbert László and Tubák, Vilmos and Endrész, Valéria and ...

Jukwaa la Wanawake na wanasiasa nchini (TWCP/ULINGO) wamelaani tabia za baadhi ya wanasiasa kutumia lugha za vitisho, uvunjifu wa amani na utulivu, katika kipindi cha nngwe ya mwisho ya kampeni za kuelekea uchaguzi Mkuu wa mwaka huu.. Aidha wameshauri kuchukuliwa hatua kwa baadhi ya vyama vya siasa vinavyofanya siasa za udini kwa kuhusisha viongozi wa dini katika kampeni zao, huku vikitambua kuwa ni kinyume cha Katiba ya nchi na Sheria ya Vyama vya siasa.. Akizungumza kwa njia ya simu wakati wa Mkutano wa Jukwaa la Wanawake viongozi kutoka vyama mbalimbali vya siasa, Taasisi za kijamii na makundi ya wenye Ulemavu kwa kushirikiana na Jukwaa la Wanawake Wanasiasa (TWCP/ULINGO) Waziri wa Nchi, Ofisi ya Waziri Mkuu, Sera, Bunge, Ajira na Wenye Ulemavu, Jenista Muhagama, alisema jukumu lililopo kwa wanawake wakati huu ni kuhakikisha amani inadumishwa katika uchaguzi.. Alisema wanawake wanapaswa kuwa mawakala wa amani ili kusaidia Watanzania kuwa na umoja wa kitaifa na kuondokana na mihemko yenye ...

​Garden Essence Oils Blue Tansy is best known for its skin care properties and as an anti-inflammatory. It has also been credited by aromatherapists as having antihistamine and antispasmodic qualities. It is believed to induce relaxation, reduce nervous tension and stress, and be beneficial for allergies.

Restore skins natural balance and purify pores with this spray-all-over hydrosol. Beaming with the soothing properties of wild picked tansy, this creation helps to calm blemishes, tone skin and lock in moisture. Blissful tip: store your mist in the refrigerator and spritz all over to revitalize on a blazing hot day. S

Bengtsson (2008a), Gustafsson (1985a), Gustafsson & van Nieukerken (1990a), Johansson, Nielsen, van Nieukerken & Gustafsson (1990a), Kasy (1983a), Laštůvka & Laštůvka (1998a, 2005a), Laštůvka, Laštůvka, Liška ao (1992a), Navickaitė, Diškus & Stonis (2014), van Nieukerken (1985a, 1986a), van Nieukerken, Laštůvka & Laštůvka (2006a, 2010a), Pröse (2006a), Segerer, Haslberger, Grünewald ao (2013a), Svensson (1966a). ...

Duru ya pili ya mazungumzo hayo ambayo yanasimamiwa na Marekani, jana yalifanyika Sharm el-Sheikh, Misri na leo yanaendelea mjini Jerusalem, Israel.

Living Poisons and stay away from Frozen Orbs.. Zandalari Dinomancers are the highest kill priority add on every door when they appear because at 50%, they drop an Orb of Control object that a player can click to force Horridon to stop more trolls from spawning from that Tribal Door.. Door 1 (Farraki Tribal Door): Farraki Wastewalkers, Farraki Skirmishers, Sullithuz Stonegazers, and a Zandalari Dinomancer. Door 2 (Gurubashi Tribal Door): Gurubashi Bloodlords, Gurubashi Venom Priests who can summon Venomous Effusions, and a Zandalari Dinomancer. Door 3 (Drakkari Tribal Door): Drakkari Frozen Warlords, Risen Drakkari Champions, Risen Drakkari Warriors, and a Zandalari Dinomancer. Door 4 (Amani Tribal Door): Amanishi Beast Shaman riding Amani Warbears, Amanishi Flame Casters, Amanishi Protectors, and a Zandalari Dinomancer. Phase 5: War-God Jalak. ...

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Living Poisons and stay away from Frozen Orbs.. Zandalari Dinomancers are the highest kill priority add on every door when they appear because at 50%, they drop an Orb of Control object that a player can click to force Horridon to stop more trolls from spawning from that Tribal Door.. Door 1 (Farraki Tribal Door): Farraki Wastewalkers, Farraki Skirmishers, Sullithuz Stonegazers, and a Zandalari Dinomancer. Door 2 (Gurubashi Tribal Door): Gurubashi Bloodlords, Gurubashi Venom Priests who can summon Venomous Effusions, and a Zandalari Dinomancer. Door 3 (Drakkari Tribal Door): Drakkari Frozen Warlords, Risen Drakkari Champions, Risen Drakkari Warriors, and a Zandalari Dinomancer. Door 4 (Amani Tribal Door): Amanishi Beast Shaman riding Amani Warbears, Amanishi Flame Casters, Amanishi Protectors, and a Zandalari Dinomancer. Phase 5: War-God Jalak. ...

Hepatitis C (HCV), hepatitis B (HBV), the human immunodeficiency viruses (HIV), and other viruses that replicate via RNA intermediaries, cause an enormous burden of disease and premature death worldwide. These viruses circulate within infected hosts as vast populations of closely related, but genetically diverse, molecules known as quasispecies. The mechanism(s) by which this extreme genetic and antigenic diversity is stably maintained are unclear, but are fundamental to understanding viral persistence and pathobiology. The persistence of HCV, an RNA virus, is especially problematic and HCV stability, maintained despite rapid genomic mutation, is highly paradoxical. This paper presents the hypothesis, and evidence, that viruses capable of persistent infection autoregulate replication and the likely mechanism mediating autoregulation--Replicative Homeostasis--is described. Replicative homeostasis causes formation of stable, but highly reactive, equilibria that drive quasispecies expansion and ...

Biomarkers lie at the heart of precision medicine. Surprisingly, while rapid genomic profiling is becoming ubiquitous, the development of biomarkers usually involves the application of bespoke techniques that cannot be directly applied to other datasets. There is an urgent need for a systematic methodology to create biologically-interpretable molecular models that robustly predict key phenotypes. Here we present SIMMS (Subnetwork Integration for Multi-Modal Signatures): an algorithm that fragments pathways into functional modules and uses these to predict phenotypes. We apply SIMMS to multiple data types across five diseases, and in each it reproducibly identifies known and novel subtypes, and makes superior predictions to the best bespoke approaches. To demonstrate its ability on a new dataset, we profile 33 genes/nodes of the PI3K pathway in 1734 FFPE breast tumors and create a four-subnetwork prediction model. This model out-performs a clinically-validated molecular test in an independent cohort of

Background aims. Cord blood is considered to be a superior source of hematopoietic stem and progenitor cells for transplantation, but clinical use is limited primarily because of the low numbers of cells harvested. Ex vivo expansion has the potential to provide a safe, effective means of increasing cell numbers. However, an absence of consensus regarding optimum expansion conditions prevents standard implementation. Many studies lack clinical applicability, or have failed to investigate the combinational effects of different parameters ...

Idhaa ya Kiswahili ya Umoja wa Mataifa inaripoti shughuli za UM kutoka makao yake makuu mjini New York na kote duniani. Masuala ya amani na usalama, maendeleo na haki za binadamu ni masuala yanayotuhusu , hivyo habari za utatuzi wa migogoro, uchaguzi, afya, umasikini, elimu na mabadiliko ya hali ya hewa yanachukua nafasi kubwa katika orodha ya mada tunazoripoti.

Idhaa ya Kiswahili ya Umoja wa Mataifa inaripoti shughuli za UM kutoka makao yake makuu mjini New York na kote duniani. Masuala ya amani na usalama, maendeleo na haki za binadamu ni masuala yanayotuhusu , hivyo habari za utatuzi wa migogoro, uchaguzi, afya, umasikini, elimu na mabadiliko ya hali ya hewa yanachukua nafasi kubwa katika orodha ya mada tunazoripoti.

Your sport for a daily rundown of everything you need to know about the NFL wont disappoint on Thursday.. Erik Kuselias and Mike Florio will speak with Bob Glauber of Newsday, who is in Charlotte for Thursday nights matchup between the Panthers and Giants. Well preview the game, discuss the impact of injuries on both sides and generally set the stage for the start of Week Three.. Well also be joined by the man averaging more than 10 yards per carry through the first two weeks of the season. Bills running back C.J. Spiller has hit the league like a rocket since Fred Jacksons injury and well find out how he plans to keep things moving now that teams are aware of his ability to make them pay.. Amani Toomer and Pete Najarian will also be on hand to give us the former players viewpoint on whether or not Jackson should lose his job because of an injury. And, as always, well be taking your Twitter questions.. It all gets going at 5 p.m. ET on NBC Sports Network.. ...

FEVERFEW: (Tanacetum parthenium or Pyrethrum parthenium or Chrysanthemum parthenium). Photographed in a wildflower garden in Beaver, PA, July 29, 2013.

J.S. Peterson. USDA NRCS National Plant Data Center (NPDC). United States, DC, Washington, USDA ARS National Arboretum. June 27, 2003. Usage Requirements.. ...

Domestic Blue Tansy essential oil, tanacetum annuum, has a high content of chamazulene, which gives Tansy oil its characteristic blue color. The oil induces relaxation and can be used to ease nervous tension and stress. Blue Tansy essential oil is also used as an anti-inflammatory and is a must in blends for burns, sunburns and bruises. It is said to be beneficial for allergies and is most effectively used as an inhalant in a diffuser or you can also put a couple of drops on a handkerchief and inhale. As an anti-inflammatory, it is also quite useful for asthma, blend it with some Ravensara for best results. Blue tansy, like the other blue oils, is used for sore muscles, sprains and strains, arthritis, rheumatism, and sciatica. Also known as Moroccan chamomile this Chamomile, which is classified botanically as a member of the Tansy family, has the most chamazulene of all the blue oils, and is characterized by an intensely sweet herbal scent and deep blue color. The anti-inflammatory effect is ...

Mohd Kamil, Nor Amani Filzah and Hamzah, Nurhidayah and Abdul Talib, Suhaimi and Hussain, NoorHana (2016) Improving mathematical model in biodegradation of PAHs contaminated soil using gram-positive bacteria. Soil And Sediment Contamination, 25 (4). pp. 443-458.. Mohd Kamil, Nor Amani Filzah and Hussain, Noor Hana and Mizad, Meizareena and Abdul-Talib, Suhaimi (2014) Enhancing performance of sphingobacterium spiritivorum in bioremediation phenanthrene contaminated sand. Remediation. The Journal of Environmental Cleanup Costs, Technologies & Techniques, 24 (3). pp. 119-128. ISSN 1520-6831. Mohd Kamil, Nor Amani Filzah and Alias, Salina and Othman, Norzila and Abdul-Talib, Suhaimi (2013) Degradation of phenanthrene by corynebacterium urealyticum in liquid culture and sand slurry. Malaysian Journal of Soil Science, 17 (1). pp. 111-126. ISSN 1394-7990. ...

Once established Feverfew (Tanacetum parthenium or Chrysanthemum parthenium (L.) Bernh. and Pyrethrum parthenium (L.) is somewhat invasive so you need to keep an eye on it, but I like those types of herbs that dont need to be babied. The flowers are delicate, producing alot of pollen. This herb is most well known as a relief for migraine headaches but can also be used to decrease blood clotting and help with arthritis. It is also very useful as a skin care herb both because it is an an antiinflammatory agent and has been shown to decrease the risk of skin cancer following UV exposure. It is used to calm red and irritated skin. The active ingredient of feverfew is parthenolide, a sesquiterpene lactone derived from its leaves and flowers. Unfortunately, some people do show skin sensitivity to feverfew ...

Dr Amani Harris specialises in Obstetrics and Gynaecology at Kareena Private Hospital in Caringbah, NSW. View bio, qualifications, contact details and how to book an appointment with Dr Amani Harris online today.

Botanical Name: tanacetum annuumAvailable Sizes: 3 mlOrigin: MoroccoCultivation: wild certified organicPart of Plant: blossomsExtraction: steamMajor Bio...

TY - JOUR. T1 - Repressed Ca2+ clearance in parthenolide-treated murine brain bEND.3 endothelial cells. AU - Tsai, Tien Yao. AU - Lou, Shyh Liang. AU - Cheng, Ka Shun. AU - Wong, Kar Lok. AU - Wang, Mei Ling. AU - Su, Tzu Hui. AU - Chan, Paul. AU - Leung, Yuk Man. PY - 2015/12/15. Y1 - 2015/12/15. N2 - Parthenolide is a sesquiterpene lactone compound isolated from the leaves and flowerheads of the plant feverfew (Tanacetum parthenium). The anticancer effects of parthenolide have been well studied and this lactone compound is currently under clinical trials. Parthenolide is also a protective agent in cardiac reperfusion injury via its inhibition of nuclear factor-κB (NF-κB). Not much is known if this compound affects signal transduction in non-tumor cells. We investigated whether parthenolide affected Ca2+ signaling in endothelial cells, key components in regulating the vascular tone. In this work using mouse cortical microvascular bEND.3 endothelial cells, we found that a 15-h treatment with ...

Feverfew (Tanacetum parthenium) - is a plant related to sunflowers and chrysanthemums. Feverfew leaves are irritating but once theyre purified, this plant has both soothing and anti-aging qualities:

A few herbs have been shown to benefit migraine sufferers. * Feverfew. This herb (Tanacetum parthenium) is probably the most effective plant for preventing migraine.

Get information, facts, and pictures about tansy at Encyclopedia.com. Make research projects and school reports about tansy easy with credible articles from our FREE, online encyclopedia and dictionary.

Chicory, Cichorium Intybus, L. also known as wild succory, blue sailors, and coffeeweed. Chicory is a bushy perennial herb with blue, lavender, or occasionally white flowers. It grows as a wild plant on roadsides. The chicory plant is one of the earliest cited in recorded literature. Horace mentions it in reference to his own diet, which he describes: Me pascunt olivae, me cichorea, me malvae (As for me, olives, endives, and mallows provide sustenance). Root chicory has been in cultivation in Europe as a coffee substitute. Chicory is well known for its toxicity to internal parasites. Root chicory contains volatile oils similar to those found in plants in the related genus Tanacetum which includes Tansy, and is similarly effective at eliminating intestinal worms. Chicory (especially the flower) was used as a treatment in Germany, and is recorded in many books as an ancient German treatment for everyday ailments. Inulin, the dietary fiber found in Chicory finds application in diabetes and ...

Sanamyan, K.; Monniot, C. (2007). Aplidium densum (Giard, 1872). In: Shenkar, N.; Gittenberger, A.; Lambert, G.; Rius, M.; Moreira Da Rocha, R.; Swalla, B.J.; Turon, X. (2017). Ascidiacea World Database. Accessed through: World Register of Marine Species at http://www.marinespecies.org/aphia.php?p=taxdetails&id=103642 on 2017-12- ...

Feverfew is a small bush with scene leaves, genus Tanacetum, belonging to family Asteraceae and native to Euro-Asia. The heral plant has been used in traditional and herbal medicine to treat fever, headaches, migraine headaches, arthritis, stomach aches, toothaches, insect bites, infertility, problems with menstruation and labor during childbirth etc. Health benefits 1. Migraine headaches …. ...

This is the Full Ingredient List for Dermalogica Retinol Clearing Oil. . Coconut Alkanes, PPG-15 Stearyl Ether, Rosa Canina Fruit Oil, Simmondsia Chinensis (Jojoba) Seed Oil, C13-15 Alkane, Coco-Caprylate/Caprate, Argania Spinosa Kernel Oil, Salicylic Acid, Caprylic/Capric Triglyceride, Isopropyl Lauroyl Sarcosinate, Retinyl Propionate, Butyl Avocadate, Phenylethyl Resorcinol, Tanacetum Annuum Flower Oil, …. ...

1b. Sphaeromeria potentilloides (A. Gray) A. Heller var. nitrophila (Cronquist) A. H. Holmgren, L. M. Shultz & Lowrey, Brittonia. 28: 261. 1976. Tanacetum potentilloides (A. Gray) A. Gray var. nitrophilum Cronquist, Leafl. W. Bot. 6: 49. 1950; Vesicarpa potentilloides (A. Gray) Rydberg var. nitrophilum (Cronquist) Kartesz. Plants 3-15 cm. Leaves mostly basal; basal mostly 1-pinnately lobed; cauline (2-)3-fid or entire. Heads 1-3(-4). Involucres 4-5.1 mm. 2n = 18.. Flowering May-Jul. Highly alkaline sites; 1600-2200 m; Calif., Idaho, Nev.. Variety nitrophila grows in northern and central Nevada and in the hills north of Snake River Plains in Idaho.. ...

The Tansy beetle is a stunning iridescent green beetle that only lives along a stretch of the River Ouse near York. The beetle gets its name from feeding on the tansy plant, and is a magnificent creature. Its quite large, about the size of a small fingernail, and when you get lots of them all on one plant it looks like a Christmas tree, its really fantastic, said Geoff Oxford at York University.. The beetle used to be more widespread, especially in the fens of East Anglia, but now they are limited to the banks of the Ouse. And although they thrive along the Ouse, they were badly hit by the floods of last year, losing about half their population. Recent research by Dr Oxford…. ...

Dr Amani Hassan is a consultant Child and Adolescent Psychiatrist, currently works as the head of Department of Child Psychiatry at Sheikh Khalifa Medical

Amani, K., Konate, I., NGbesso, M.F.D.P., Attien, Y.P., Fondio, L., Filali-Maltouf, A. and Tidou, A.S. (2019) Phenotypic and Symbiotic Diversity of Rhizobia Isolated from Root Nodules of Soybean [Glycine max (L.) Merrill] in Côte dIvoire. International Journal of Current Microbiology and Applied Science, 8, 766-774.

Mechanisms that affect respiratory virus-cell interplay in the context of humans are finely tuned to the environment of the host (4, 5). To understand natural viral infection and the features that govern infectivity and transmissibility in humans, we have endeavored to analyze field strains in airway tissues. We have shown for human parainfluenza virus type 3 that conclusions drawn from laboratory strains can be misleading with regard to the receptor interaction and viral fusion properties that govern entry and fitness in vivo (4, 5). Analysis of clinical strains suggests that the HN-F fusion pairs of circulating HPIV-3 viruses maintain a balance of properties that result in an inverse correlation between fusion in cultured cells and growth in vivo; the fusion complex operates under specific constraints that govern viability in the different environments of cell cultures and human beings.. We have previously used whole-genome sequencing of field strains of HPIV-3 isolated from humans and grown ...

Using hybridizing Magnetic Relaxation Nanosensors (hMRS). Microoganims associated with disease or contamination of the environment present serious challenges that threaten public health. For example: pathogenesis relies on the survival of microorganisms within host cells, such as macrophages and dendritic cells, or tissue. This mode of infection, with or without clinical symptomology, hampers bacterial detection, preventing correct diagnosis. Consequently, the physician cannot proceed to assigning an appropriate treatment course, delaying the clearance of the pathogen from the body. Traditional methods such as culture or ELISA cannot effectively detect intracellular pathogens in biological specimens as the microorganism is hidden away within immune cells; and Polymerase Chain Reaction (PCR), while highly specific and sensitive, is laborious, time-consuming and typically requires homogeneous and pure DNA samples. Because of this, there exists a need for robust, accurate and timely identification ...

Sleep/wake and affective behaviors are interactive and complex. Transcriptomic alterations that are associated with changes in sleep/wake and affective states have provided important clues to the mechanisms underlying sleep, affective functions, and neuropsychiatric disorders. Here, we performed transcriptional profiling across four brain regions in a (B6 × 129) F2 mouse population that was extensively phenotyped for sleep and affective behaviors, elucidating how interactions between sleep and affective functions emerged from multilevel transcriptomic organizations across brain regions. At the single-gene level, we showed that genetically regulated genes were associated with sleep and behavioral phenotypes across brain regions and that the number of eQTL genes associated with both sleep and affective behaviors was higher than expected by random chance, indicating a convergence of genes that are relevant to different domains of neurobehavioral functions. In particular, we highlighted a number of ...

Dr. Aleem joined the Institute of Molecular Medicine (IMM) at Phoenix Childrens hospital in early 2013. As part of a precision medicine approach to identify novel therapeutic targets and improve treatment options for pediatric cancers, Dr. Aleems translational research focuses on (1) understanding the association between cancer genotype and phenotype, i.e. how the genomic/transcriptomic alterations in cancer cells lead to cancer-specific biological effects, such as uncontrolled cell proliferation, drug resistance and escape from apoptosis, (2) Identification of drugs targeting cancer stem cells and studying the mechanisms of action of drugs currently in clinical trials, as well as (3) studying the effect of the tumor microenvironment on the response of cancer cells to therapy. Dr. Aleem applies a variety of innovative technologies in her research including next-generation sequencing, functional proteomics, kinome profiling, in vitro 3D cell culture models and in vivo mice models. Current ...

Blue tansy essential oil is has a sweet, pleasant aroma, any use becomes uplifting whether its an addition to your nighttime routine or diffused throughout your home.

The plume moth below was swept from a large area of tansy and it may be the tansy plume Gillmeria ochrodactyla. Checking the labial palps with a hand lens from the side and above, they certainly do not protrude beyond the facial tuft, which is a feature of the tansy plume. However, the tansy plume is supposed to have the hind legs `slightly banded` a feature that is not visible in the view from above, though from below, there is some evidence of that. Another possibility, of course, is the yarrow plume (yarrow also grows nearby). Which one is it, please ...

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The invention discloses a kind of glory-hole side slopes to cover green new method, using following technique, step：Rockbolt installation hole (8) are bored by 35~50cm distances in open-pit slope face, support Short bolt (1) is rammed into rockbolt installation hole (8)；Wire netting (5) is covered on open-pit slope face；Plank (4) is fixed on steel wire lashing on the two neighboring support Short bolt supporting section (3) of same level；It will be in earthing (6) injection to the open-pit slope face in wire netting (5)；It is laid with fixed geotextiles (7) on the outer surface of wire netting (5), support Short bolt (1), plank (4), wire netting (5), earthing (6), geotextiles (7) and open-pit slope face is made to form a firm overall structure；6) the careless or/and other plant grown is conserved.The present invention solve the problems, such as large surface mine abrupt slope cover it is green it is difficult, of high cost, effect is poor, environmental benefit, safety benefit, visual

I dont think that the chemo makes sense if the vet hasnt identified a tumour and of course, the side effects are likely to worsen your cats condition. The good thing about what I am suggesting is that it may or may not work, but it is unlikely to leave him in a worse state, which cannot be said for the chemo. I would therefore try the prednisolone and Winstrol before I agreed to more chemo if it were my cat. Amani From: Felvtalk ,[email protected], On Behalf Of Katy Brown Sent: October 18, 2018 3:28 PM To: [email protected] Subject: Re: [Felvtalk] Batman Felv Positive Having Neurological issues. Amani, That is very insightful. Im not convinced he has lymphoma because his decline was so rapid. Within hours he went from walking to having completely rigid legs. And today he is starting to decline. Im wondering if there is something else I can give him besides the 5 mg of Prednisolone and the Clindamycin. The vet said he he keeps declining we could do another form of ...

1. Takes note of the report of the Chairperson of the Commission on the situation in the Sahel region, in particular the paragraphs on the situation in the northern part of Mali [PSC/MIN/3.(CCCXIV)];. 2. Expresses its deep concern about the situation created by the attacks that the rebel elements of the Mouvement national pour la Libération de lAzawad - MNLA (National Movement for the Liberation of Azawad) and other rebel groups, including major displacement of people within Mali and towards the neighboring countries. Council stresses the seriousness of the threats that this new crisis poses for peace, security and stability in Mali and in the region as a whole, particularly in view of the overall fragility of the situation, which is marked by the proliferation of all types of arms, terrorism and transnational organized crime;. 3. Reaffirms the relevant provisions of decision Assembly/AU/Dec.408 (XVIII), adopted by the 18th Ordinary Session of the Assembly of the Union, held in Addis Ababa, on ...

This is a long shot but fingers crossed someone will be able to help. I am trying to trace an old horse just to find out hows she doing and what she is up to. shes a mare and is called Tolcarne Tansy but we called her Tansy for short. She is liver chestnut with no socks and no marks on her face, just full over liver chestnut. She was born on 24th July 1998, making her about 19yrs now, and is 16hh. We sold her to a riding stables called Finlake (Chudleigh, Newton Abbot) and they sold her onto a

Herbal vinegars can be used for salad dressings, a tablespoon at a time for combating digestive ailments (1 tablespoon 20 minutes before a meal can help you avoid indigestion and heart burn), a hair rinse (great for relieving dandruff, removing the last of the shampoo in the hair and making the hair shiny) and more. They are an excellent tonic for the entire digestive tract and can assist your body to regulate its acid/alkaline balance. Externally, they can be applied to the skin as a fomentation to soothe irritated, burned, itching or feverish skin. They are typically added 1:3 with water (1 part vinegar to 3 parts water). ...

Hotuba ya Rais Bashar Al Assad akitoa wito wa kuwepo kwa amani nchini humo imekumbana na ukosoaji mkubwa na upande wa upinzani na kimataifa, huku Iran pekee ikiunga mkono msimamo wake.

by Fullman, Nancy and Barber, Ryan M and Abajobir, Amanuel Alemu and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulkader, Rizwan Suliankatchi and Abdulle, Abdishakur M and Abera, Semaw Ferede and Aboyans, Victor and Abu-Raddad, Laith J and Abu-Rmeileh, Niveen M E and Adedeji, Isaac Akinkunmi and Adetokunboh, Olatunji and Afshin, Ashkan and Agrawal, Anurag and Agrawal, Sutapa and Ahmad Kiadaliri, Aliasghar and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Miloud Taki Eddine and Aichour, Amani Nidhal and Aichour, Ibtihel and Aiyar, Sneha and Akinyemi, Rufus Olusola and Akseer, Nadia and Al-Aly, Ziyad and Alam, Khurshid and Alam, Noore and Alasfoor, Deena and Alene, Kefyalew Addis and Alizadeh-Navaei, Reza and Alkerwi, Alaa and Alla, François and Allebeck, Peter and Allen, Christine and Al-Raddadi, Rajaa and Alsharif, Ubai and Altirkawi, Khalid A and Alvis-Guzman, Nelson and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Ansari, ...

Mheshimiwa Naibu Spika, kama inavyofahamika nchi yetu, hususan maeneo ya mipakani, imekuwa na tatizo la wahamiaji ambao hufahamika kama walowezi walioingia na kuishi nchini kwa miaka mingi. Wahamiaj hawa waliingia nchini kwa sababu mbalimbali tangu wakati wa ukoloni, ikiwemo kufanya kazi katika mashamba na migodi ya wakoloni, vita vya kikabila na uhaba wa ardhi katika nchi zao na pia kuvutiwa na hali ya amani iliyopo katika nchi yetu. Kwa mujibu wa Sheria ya Uraia, Sura Namba 357, kama ilivyorejewa mwaka 2002 walowezi hawa hawatambuliwi kama raia wa Tanzania ...

Mheshimiwa Mwenyekiti, suala la demokrasia na utawala bora na haki za binadamu nchini mwetu linapotea kila siku. Leo Tanzania, wananchi wanatekwa na kuuawa, wanasiasa na wanaharakati pia wanahujumiwa na Tanzania hata waandishi wa habari na vyombo vya habari hawako salama. Hali hii haileti afya kwa Taifa. Tunaiomba sana Serikali na Wizara ya Mambo ya Ndani, usalama kwa wananchi ni jambo muhimu kwa mustakabali wa amani ya Taifa letu ...

A young mother and her young son killed in a shooting in Boston are being laid to rest. The funeral for 21-year-old Eyanna Flonory and 2-year-old Amani Smith is scheduled to take place at Morning Star Baptist Church on Wednesday morning.

NAIROBI, Kenya, Mar 18 - Amani Coalition leader Musalia Mudavadi has explained that he has not signed any deal yet with President-elect Uhuru Kenyattas Ju - Kenya breaking news | Kenya news today | Capitalfm.co.ke

Pensjonat Miramont Retreat Zanzibar położony jest w miejscowości Kilima Juu Pwani na Zanzibarze, 34 km od miasta Zanzibar. Oferuje on 2 odkryte baseny, w tym jeden całoroczny. Do dyspozycji Gości jest tu także taras słoneczny z widokiem na morze oraz bar. Na miejscu dostępny jest ponadto bezpłatny prywatny parking. Obiekt zapewnia usługi pralni chemicznej. W okolicy panują doskonałe warunki do uprawiania rozmaitych form aktywnego wypoczynku, w tym nurkowania z rurką i akwalungiem. Na miejscu można wypożyczyć samochód i rower. Pensjonat Miramont Retreat Zanzibar położony jest 21 km od miejscowości Nungwi i 19 km od wioski Kendwa. Odległość od międzynarodowego lotniska im. Abeid Amani Karume na Zanzibarze wynosi 38 km. Więcej ...

Mariam E. A. Al Hajeri, Mona Saleh Al Ansarri, Amani Ali Al Hajeri, Samia Hssan Al Qattan, Maryam Adam Ali, Lana Saleh, Shaikha AlKowari, Noora Adam Ali ...

by Gakidou, Emmanuela and Afshin, Ashkan and Abajobir, Amanuel Alemu and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulle, Abdishakur M and Abera, Semaw Ferede and Aboyans, Victor and Abu-Raddad, Laith J and Abu-Rmeileh, Niveen M E and Abyu, Gebre Yitayih and Adedeji, Isaac Akinkunmi and Adetokunboh, Olatunji and Afarideh, Mohsen and Agrawal, Sutapa and Agrawal, Anurag and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Amani Nidhal and Aichour, Miloud Taki Eddine and Aichour, Ibtihel and Akinyemi, Rufus Olusola and Akseer, Nadia and Alahdab, Fares and Al-Aly, Ziyad and Alam, Tahiya and Alam, Noore and Alam, Khurshid and Alasfoor, Deena and Alene, Kefyalew Addis and Ali, Komal and Alizadeh-Navaei, Reza and Alkerwi, Alaa and Alla, François and Allebeck, Peter and Al-Raddadi, Rajaa and Alsharif, Ubai and Altirkawi, Khalid A and Alvis-Guzman, Nelson and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Amoako, Yaw Ampem and Ansari, ...

Arlette Kpebe, Martino Benvenuti, Chloé Guendon, Amani Rebai, Victoria Fernandez, Sébastien Le Laz, Emilien Etienne, Bruno Guigliarelli, Gabriel García-Molina, Antonio L. de Lacey, Carole Baffert, Myriam Brugna. ...

The ranger knew this wouldnt be as easy as it looked. Hiro knew what he was doing and his pokemon were obviously well trained. Elizabeth just had to keep from getting too cocky. She watched the lapras warily as Ayla stretched out her wings. The match ups so far hadnt really been what the ranger had initially envisioned. The plan had been if ludicolo had shown then Ayla or Tansy were to be the counter, their flying and poison type moves being perfect against the part grass type. But Cecylia had held her own with Signal Beam which still did a nice number on the dual type. And it was Cecylia who shouldve faced off with Lapras as any ice type moves wouldnt have been quite as troublesome to the electric type ...