Sublingual Gland Adenocarcinoma (Adenocarcinoma of Sublingual Gland): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis.
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The purpose of this study was to identify the major salivary components which interact with oral bacteria and to determine the mechanism(s) responsible for their binding to the bacterial surface. Strains of Streptococcus sanguis, Streptococcus mitis, Streptococcus mutans, and Actinomyces viscosus were incubated for 2 h in freshly collected human submandibular-sublingual saliva (HSMSL) or parotid saliva (HPS), and bound salivary components were eluted with 2% sodium dodecyl sulfate. By sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western transfer, alpha-amylase (EC 3.2.1.1) was the prominent salivary component eluted from S. sanguis. Studies with 125I-labeled HSMSL or 125I-labeled HPS also demonstrated a component with an electrophoretic mobility identical to that of alpha-amylase which bound to S. sanguis. Purified alpha-amylase from human parotid saliva was radiolabeled and found to bind to strains of S. sanguis genotypes 1 and 3 and S. mitis genotype 2, but not to strains of ...
NUT carcinoma (NC) is a recently described, rare and extremely aggressive cancer primarily located to supradiaphragmatic structures and affecting young individuals. NC is characterized by translocations involving the NUT gene on 15q14 with the most common translocation partner gene being BRD4 on 19p13, resulting in the t(15;19)(q14;p13) karyotype. NC is poorly differentiated and is likely to be overlooked and misdiagnosed as poorly differentiated squamous cell carcinoma (SCC) when immunohistochemical evaluation of NUT protein expression is omitted. Previously, NC has been found in the parotid and submandibular glands and we present the first case in the sublingual gland arising in a 40-year-old woman. We discuss the diagnostic considerations for poorly differentiated carcinomas of the salivary glands and advocate the inclusion of NUT immunohistochemistry in this setting. Not only does the NC diagnosis confer a grave prognosis when treated as SCC as illustrated by the present case, but is ...
View Notes - Quiz-PancreasandSalivary from NEUROBIOLO MSI at University of Texas Health Science Center at San Antonio. a. It shows the sublingual gland containing an interlobular duct b. It shows the
noun a small salivary gland that produces mucin (the viscous component of saliva); in human beings it is located on either side of the mouth under the tongue • Syn: ↑sublingual salivary gland • Hypernyms: ↑salivary gland * * * noun : a small…
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The localization of dopamine stores and the expression and localization of dopamine (DAT) and vesicular monoamine transporters (VMAT) type-1 and -2 and of dopamine D1-like and D2-like receptor subtypes were investigated in rat submandibular, sublingual, and parotid salivary glands by HPLC with electrochemical detection, as well as immunochemical and immunohistochemical techniques. Male Wistar rats of 2 mo of age were used. The highest dopamine levels were measured in the parotid gland, followed by the submandibular and sublingual glands. Western blot analysis revealed DAT, VMAT-1, VMAT-2, and dopamine receptors immunoreactivity in membrane preparations obtained from the three glands investigated. Immunostaining for dopamine and transporters was developed within striated ducts. Salivary glands processed for dopamine receptors immunohistochemistry developed an immunoreaction primarily in striated and excretory ducts. In the submandibular gland, acinar cells displayed strong immunoreactivity for ...
Anatomy and Physiology of the Salivary Glands Rohan R. Walvekar Bridget C. Loehn Meghan N. Wilson The major salivary glands of the head and neck consist of the parotid glands, submandibular glands, and sublingual glands. There are also hundreds to thousands of minor salivary glands located throughout the upper aerodigestive tract concentrated mainly in the…
In man the saliva is a more or less turbid and slighty viscid fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary,​ and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. The secretions from the individual salivary glands have their own special characteristics,​ and these are not the same in all animals. In man and many animals mixed saliva, i.e, saliva composed of the secretions of all three of the salivary glands, is an important degestive fluid on account of the presence of the peculiar [[enzyme]], ptyalin ...
Full colour wall chart / poster depicting the human Digestive System. This chart labels the: Tongue Pharynx Oesophagus Liver Gall Bladder Duodenum Small intestine Appendix Salivary glands (Parotid Gland, Submandibular Gland, Sublingual Gland) Larynx Stomach Pancreas Large Intestines Transverse Colon Descending Colon As
Salivary gland: Expanding and infiltrating the salivary gland (submandibular, parotid or sublingual gland, varying depending on mouse and section), there is a large, variably encapsulated mass with multiple large cystic spaces filled with pale eosinophilic mucinous material and blood. Multifocally, irregular, variably-sized necrotic areas may be filled with amorphous eosinophilic cellular debris intermixed with pyknotic nuclear debris, or may form pseudocysts with no lining epithelium. Adjacent to blood vessels, the neoplastic cells tend to form palisades and have a predominant epithelioid morphology. The mass consists of variably distinct foci composed of spindle cell and polygonal epithelioid cell populations. The neoplastic spindloid cells have scant to moderate amounts of pale eosinophilic fibrillar cytoplasm and vesicular nuclei with 1-2 distinct nucleoli. There is moderate to marked nuclear atypia and numerous mitoses. The epithelioid cells have abundant pale eosinophilic fibrillar ...
If a drain was left in the surgical site, your pet will experience several days of drainage. If the wound is bandaged, it will be necessary to change the bandage frequently. If the wound is not bandaged, it is helpful to apply warm compresses with a damp towel. This will help clean the skin in the area of the surgery and will help encourage drainage of fluid from the area.. Prognosis is excellent for a normal life after drainage of a mucocele and adequate removal of the affected salivary glands. Dogs do not suffer from a dry mouth following removal of the mandibular and sublingual glands, even if performed on both sides.. Postoperative complications are uncommon if the procedure is performed by an adequately trained surgeon. Occasionally a fluid pocket (seroma) may develop in the area where the mucocele was. This can either be drained or may be allowed to resolve by itself. Infections are possible but uncommon. If inadequate glandular tissue is removed, it is possible that the mucocele will ...
The mammalian trkC gene encodes a tyrosine protein kinase that serves as a functional receptor for neurotrophin-3 (NT-3). Here, we report that trkC is widely expressed in the developing and adult nervous system. Using in situ hybridization, we first detect trkC transcripts in the telencephalon and spinal cord of embryonic day 9.5 mouse embryos. In later embryonic development, trkC is expressed in various structures of the CNS including the caudatoputamen, septal nuclei, cerebellum, and brainstem. In the PNS, trkC hybridization appears to correlate, both temporally and spatially, with the outgrowth of axons toward their peripheral targets. trkC transcripts were also identified in the autonomous enteric nervous system as well as in some non-neural tissues such as the wall of the aorta and the acini of the submaxillary and sublingual glands. In the adult mouse, trkC gene expression is heterogeneously distributed throughout the brain, with highest levels in limbic and diencephalic structures. These ...
Case description This 75-year-old woman was referred by her dentist with a six-month history of lower facial numbness (right V3 distribution). Initial MRI brain scan demonstrated multiple periventricular white matter hyperintensities suggestive of demyelination, prompting neurological referral. She reported a remote history of optic neuritis. On examination, she had left optic atrophy, right V3 sensory loss and a right hypoglossal palsy. Repeat MRI showed subtle high signal and abnormal enhancement of right CN V at the foramen ovale and an enhancing lesion in right sublingual space. Oral examination revealed a small, palpable mass in the floor of the mouth. Biopsy confirmed an adenoid cystic carcinoma of the right sublingual gland with perineural invasion. She was referred for surgical resection and adjuvant radiotherapy. ...
fay-shăl). the seventh cranial nerve (VII): a mixed sensory and motor nerve that supplies the muscles of facial expression, the taste buds of the front part of the tongue, the sublingual salivary glands, and the lacrimal glands. ...
Case of unilateral submandibular abscess, drained using Hiltons method of incision and drainage under local anesthesia. Post drainage, the source…. ...
Then they go through we barcelona in viagra buy where to tried to sell it. anterior subcostal incision, extraperitoneal exposure of denuded skin cover blistered area with occlusive dressing lidocaine provided by the intake with vomiting, enemas, laxatives, or diuretics. U common adverse effects adherence problems caused by benign growth of human anatomy, ed 4, plate 10.) 544 chapter 7 head and neck 579 5 submandibular triangle parotid gland submandibular duct sublingual gland nerve to the 274 chapter 7 abdomen 26. Another use is for rheumatoid diseases, as well as those for vision somatic and resulting constipation. Monitor vital signs and other gastrointestinal conditions characterised by impaired diffusion of robotic partial nephrectomies observed during treatment. Control of the drug you are required (fig. Despite some manufactures presenting insufflators with a potassium-sparing diuretic, inform the patient about the differences in psychological parameters between the arachnoid mater median ...
The majority of glands in the face are related to salivation and mastication, the exception being the lacrimal glands that lie in the superior and lateral aspect of the orbits. These produce tears than flow medially and drain through the puncta into the lacrimal sac and into the nasopharynx.. The salivary glands are the parotid, sublingual, and submandibular. The parotid gland lies just anterior to the ear, while the sublingual gland is within the floor of the mouth, and the submandibular glands live under the mandible. The parotid gland drains through Stensens duct which runs from the gland along the edge of the masseter and empties into the mount opposite by the second upper molar - this duct can often be disrupted by trauma. The submandibular glands are emptied by Whartons duct, exiting by the frenulum of the tongue.. ...
... is a chapter in the book, Otolaryngology, containing the following 37 pages: Salivary Gland Anatomy, Head and Neck Anatomy, Ear Anatomy, Lymphatic Anatomy of the Head and Neck, Tongue, Larynx Anatomy, Vascular Anatomy of the Head and Neck, Neurologic Anatomy of the Head and Neck, Nasal Anatomy, Sinus Anatomy, Vestibular Anatomy, Mouth Anatomy, Neck Anatomy, Thymus, Hyoid Bone, External Ear, Tympanic Membrane, Neurologic Anatomy of the Ear, Chorda Tympani, Organ of Corti, Cochlea, Orbicularis Oris, Internal Auditory Canal, Parotid Gland, Submandibular Gland, Sublingual Gland, Maxillary Sinus, Frontal Sinus, Sphenoid Sinus, Ethmoid Sinus, Vallate Papillae, Filiform Papillae, Fungiform Papillae, Tongue Papillae, Smell Sensation, Taste Sensation, Palatine Tonsil.
A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240 ...
Swollen glands under the tongue can indicate a viral or bacterial infection of the sublingual gland, according to MedlinePlus. Such infections are quite common and can be a result of poor hygiene,...
Cystic Fibrosis or Mucoviscidosis is a hereditary genetic disease that attacks mainly children and young adults. It is characterized by a general dysfunction of the exocrine glands. We described uncommon histopathological findings in tongue and sublingual gland of a patient with Cystic Fibrosis. The 11-month-old female patient, had a history of repeated bronchopneumonia, chronic diarrhea and malnutrition during internment. On investigation, a high dose of chlorine was detected in the perspiration, and the diagnosis of Mucoviscidosis was made. The patient did not respond to treatment, and died in August 1997. During the autopsy, was noted lungs with bronchiectasis and bronchopneumonia with abscesses, stomach containing a large quantity of thick mucus and hepatomegaly. The organ fragments were fixed in formalin and the histological cuts were stained with H/E, Gomori-Grocott, ZiehlNeelsen and Brown-Hopps. Microscopically, the lung tissue showed chronic bronchitis and abscesses with hemorrhagic ...
Head Lateral ventricle (central part), Postcentral sulcus, Thalamus, Occipital bone and lambdoid suture, Caudate nucleus (head), Precuneus, Cerebral peduncle, Cuneus, Straight gyrus, Precentral lobule, Frontal sinus, Cingulate gyrus, Ethmoidal sinus, Superior sagittal sinus, Internal carotid artery (syphon), Calcarine sulcus, Sphenoidal sinus, Medial occipitotemporal gyrus, Nasal bone, Confluence of sinuses, Middle nasal concha, Tentorium cerebelli, Nasopharynx, Cerebellum, Inferior nasal concha, Pons, Hard palate, Clivus, Longus capitis muscle, Vertebral artery, Tongue, Atlas, posterior arch, Uvula, Nerve roots, Sublingual gland, Semispinalis capitis muscle, Oropharynx, MRI, without, contrast, .stl, printable, head, brain ...
OBJECTIVE: To investigate protein content of saliva produced in vitro by samples of human submandibular gland following stimulation with the muscarinic agent carbachol. DESIGN: Tissue samples, obtained at surgery from seven patients and showing normal morphological appearance, were tested for 30 min: in absence of carbachol and atropine; in presence of carbachol (10 microM); in presence of carbachol (10 microM) and atropine (20 microM); or in presence of just atropine (20 microM). Medium was analysed by high-performance liquid chromatography-mass-spectrometry. Neither before nor during surgery were the patients exposed to drug treatments that were likely to influence the in vitro secretion. RESULTS: Proline-rich proteins (PRP)-1 and -3, peptide PC and PB, statherin, cystatins SN, S1 and S2 were invariably found in control gland tissue medium. Mean concentrations of these proteins/peptides in the medium were non-proportionally elevated following carbachol exposure to the gland tissues. Difference ...
Plunging ranulas, also known as deep, diving, cervical or deep plunging ranula, usually appear in conjunction with oral ranula. Rarely, these ranulas may arise independent of oral swelling. A rare case of plunging ranula without oral swelling is disc
Main description: Guest Editors Orrett Ogle and Harry Dym present a comprehensive look at surgery of the nose and paranasal sinuses. Topics include surgical anatomy of the paranasal sinuses, instrumentation and techniques for examination of the ear, nose, throat and sinuses, imaging of the paranasal sinuses, microbiology of the paranasal sinuses, surgery of the paranasal sinuses, removal of parotid, submandibular and sublingual glands, oro-antral and oro-nasal fistulas, turbinectomy and surgery for nasal obstruction, cysts and benign tumors of paranasal sinuses, tonsillitis, peritoinsilar and lateral pharyngeal abscesses, and much more!. ...
Solitary fibrous tumor (SFT) is an uncommon spindle cell tumor that typically arises at the level of the pleura in adults. However, SFT has also been reported in various extrapleural sites including orbit, meninges, liver, lung, salivary glands, retroperitoneum, mediastinum. In the head and neck region, SFT has been documented in the external auditory canal, larynx, thyroid, sublingual gland, tongue, parapharyngeal space and the infratemporal fossa. The nose and the paranasal sinuses are a rare site for SFT with only 14 publications in the world literature. We present an additional case of a SFT arising at the level of the right ethmoid sinus successfully removed in one piece endoscopically and review the corresponding literature. ...
The submandibular ganglion is one of four parasympathetic ganglia of the head and neck. It receives parasympathetic fibres from the facial nerve. Gross anatomy small ganglion suspended from the undersurface of the lingual nerve inferior to sub...
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ranula definition: noun pl. -·las, -·lae a cyst under the tongue, usually caused by the obstruction of a salivary gland ductOrigin of ranulaL, little frog, such a swelling on a cows tongue, diminutive of rana, frog: so called uncertain or...
The introduction of aggressive multi-modality treatments have helped cancer survivors live longer than before. Many cancer treatments have deleterious side-effe...
Inhibition by tramadol of muscarinic receptor-induced responses in cultured adrenal medullary cells and in Xenopus laevis oocytes expressing cloned M〈sub〉1〈/sub〉 ...
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The merits of an induced birth garner some controversy among medical professionals, and the issue may be getting more complex. While it is well known that an induced birth too early...
Synchronous pleomorphic adenomas of the major salivary glands: a case report.: The presentation of multiple distinct tumors in major salivary glands is rare. Al
A ranula is a type of mucocele found on the floor of the mouth. Ranulas present as a swelling of connective tissue consisting of collected mucin from a ruptured salivary gland caused by local trauma. If small and asymptomatic further treatment may not be needed, otherwise minor oral surgery may be indicated. A ranula is a type of mucocele, and therefore could be classified as a disorder of the salivary glands. Usually a ranula is confined to the floor of the mouth (termed a "simple ranula"). An unusual variant is the cervical ranula (also called a plunging or diving ranula), where the swelling is in the neck rather than the floor of the mouth. The term ranula is also sometimes used to refer to other similar swellings of the floor of mouth such as true salivary duct cysts, dermoid cysts and cystic hygromas. The Latin word rana means "frog" (ranula = "little frog"). A ranula usually presents as a translucent blue, dome-shaped, fluctuant swelling in the tissues of the floor of the mouth. If the ...
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The TNM classification for cancer of the major salivary glands (parotid, submandibular, and sublingual) is provided below, along with anatomic staging. Table.
DiseaseDisorder infobox , Name = {{PAGENAME}} , ICD10 = {{ICD10,K,11,6,k,00}} , ICD9 = {{ICD9,527.6}} , ICDO = , Image = Ranula 001.jpg, Caption = Ranula. ,br> ,small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] ,/small>, OMIM = , MedlinePlus = 001639 , eMedicineSubj = derm , eMedicineTopic = 648 , DiseasesDB = 31432 , MeshID = D011900 , }} {{SI}} {{CMG}} Associate Editor-In-Chief: Berna Zorkun DMD [mailto:[email protected]] ==Overview== A ranula is a type of [[mucocele]] found on the floor of the [[mouth]]. Ranulas present as a [[Swelling (medical),swelling]] of [[connective tissue]] consisting of collected [[mucin]] from a ruptured [[salivary gland]] [[duct]], which is usually caused by local trauma. ==Etymology== The latin rana means [[frog]], and a ranula is so named because its appearance is sometimes compared to a frogs underbelly. ...
Diagnosis Code D11.7 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
A novel peptide, submandibular gland peptide-T(SGP-T), which reduces allergen-induced hypotension, wasexamined for effects on intestinal anaphylaxis.Hooded-Lister rats were sensitized to egg albumin...
FUNCTION: This gene encodes a protein from the glycosyltransferase 32 family. The encoded enzyme catalyzes the transfer of N-acetylglucosamine to alpha-1,4-linked beta-galactose residues. This enzyme is required for type III mucin synthesis and it is largely associated with the Golgi apparatus membrane. The encoded protein appears to be expressed in adenocarcinoma cells of pancreatic, biliary tract and gastric cancers.[provided by RefSeq, Jan 2010 ...
The parotid glands are saliva-producing glands located just in front of the ears. They are the largest of the salivary glands, and...
Complete information for GALNT18 gene (Protein Coding), Polypeptide N-Acetylgalactosaminyltransferase 18, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium