TY - JOUR. T1 - Previous use of aspirin and baseline stroke severity: an analysis of 17850 patients in the international stroke trial. AU - Ricci, Stefano. AU - Lewis, Stephanie. AU - Sandercock, Peter. PY - 2006/6/1. Y1 - 2006/6/1. N2 - Background and Purpose- Some studies suggest that taking aspirin regularly at the time of the onset of stroke reduces stroke severity. Other studies suggest the converse (ie, that previous aspirin therapy is associated with greater stroke severity). We sought to examine this question among the patients enrolled in the International Stroke Trial (IST).Methods- Analysis of the associations of reported use of aspirin in the 3 days before randomization in IST with baseline stroke severity (as assessed by stroke clinical syndrome, predicted outcome at 6 months, and observed outcome at 6 months). We adjusted analyses for confounding factors.Results- We excluded those patients who were first scanned after trial entry and were found to have an intracerebral hemorrhage ...
Objective: Acute childhood stroke is an emergency requiring a high level of awareness among first-line healthcare providers. This survey serves as an indicator of the awareness of, the interest in, and knowledge of childhood stroke of German pediatricians. Methods: Thousand six hundred and ninety-seven physicians of pediatric in- and outpatient facilities in Bavaria, Germany, were invited via email to an online-survey about childhood stroke. Results: The overall participation rate was 14%. Forty-six percent of participants considered a diagnosis of childhood stroke at least once during the past year, and 47% provide care for patients who have suffered childhood stroke. The acronym FAST (Face-Arm-Speech-Time-Test) was correctly cited in 27% of the questionnaires. Most commonly quoted symptoms of childhood stroke were hemiparesis (90%), speech disorder (58%), seizure (44%), headache (40%), and impaired consciousness (33%). Migraine (63%), seizure (39%), and infections of the brain (31%) were most ...
EXECUTIVE SUMMARY Stroke Types and Incidence Endovascular Stroke Management Techniques and Tools Procedures and Markets. Procedures and Markets by Geography Suppliers Summary Exhibit 1: Global Incidence of Stroke by Major Type, 2013-2019 Summary Exhibit 2: Global Endovascular Interventions for Acute Stroke Management by Major Type, 2013-2019 Summary Exhibit 3 Global Market for Acute Stroke Therapy Products by Major Type, 2013-2019 Summary Exhibit 4: Endovascular Interventions for Acute Stroke Management by Major Geography, 2013-2019. Summary Exhibit 5: Global Endovascular Acute Stroke Therapies Market by Major Geography, 2013-2019. Summary Exhibit 6: Global Endovascular Acute Stroke TherapiesMarket, Estimated Supplier Shares, 2014 1.0 ETIOLOGY & EPIDEMIOLOGY OF ACUTE STROKE. 1.1 Overview of the Brain. 1.1.1 Cerebral Arterial Blood Supply 1.1.2 Sites of Plaque and Emboli Formation 1.2 Etiology of Stroke 1.2.1 Ischemic Stroke. 1.2.1.1 Major Types. 1.2.1.1.1 Thrombotic Stroke 1.2.1.1.2 Embolic ...
Latest industry research report on Acute Ischemic Stroke Diagnosis and Treatment Market. Ischemic stroke is caused by a dysfunction in the supply of blood to the brain due to emboli, thrombus or atherosclerosis occurring in cerebral arteries. According to a World Health Organization (WHO) estimate, around 17 million people die every year due to cardiovascular diseases.. Heart attacks and strokes respectively account for the highest number of deaths due to cardiovascular diseases, globally. The statistics of the Centres for Disease Control and Prevention suggest that about 87% of all strokes are ischemic strokes. Stroke is one of the leading causes of long term disability, occurring at a higher rate in the old age population.. Get Free Sample Report Of Acute Ischemic Stroke Diagnosis and Treatment Market @ http://www.marketresearchstore.com/report/world-acute-ischemic-stroke-diagnosis-and-treatment-market-71669#RequestSample. Moreover, stroke leads to 1 out of every 20 deaths, costing around $34 ...
In this study, a newly developed risk assessment model for stroke onset was shown by several statistical indicators to be superior to the gold-standard Framingham Stroke Risk Score. This new stroke risk score model(NEW-STROKE) was developed using a novel, model-building technology, called synthesis analysis, that allowed for the incorporation of seven additional literature-derived risk factors into the original FSRS.. Compared with the discrimination of these two models, the NEW-STROKE model had higher modified C-statistics than the original FSRS model in the overall group and in the female subgroup in the presence of censoring for survival time. This observation illustrates that the NEW-STROKE model has higher precision in both the overall group and the female subgroup in predicting stroke risk score. When evaluating calibration, the NEW-STROKE model outperformed the original FSRS model as evidenced by smaller Hosmer-Lemeshow chi-square values (,20) after recalibration in the overall group and ...
To the Editor:. Although there have been major advances in stroke diagnosis, prevention, and treatment during the past decade, stroke is the still third most common cause of death in Taiwan.1 The intravenous tissue plasminogen activator (tPA) is currently the only approval medical therapy for acute ischemic stroke within a 3-hour window2,3 and is recommended by Taiwan Stroke Societys Guidelines for the Management of Acute Ischemic Stroke.4 In the Taiwan Thrombolytic Therapy for Acute Ischemic Stroke Study5 and thrombolysis with alteplase for acute ischemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study6 both showed that intravenous tPA is safe and effective in routine clinical use for acute ischemic stroke within 3 hours. However, in Taiwan Thrombolytic Therapy for Acute Ischemic Stroke Study, only 241 patients had received tPA treatment in 32 months of observation.5 A survey of stroke center status in Taiwan showed that ,1% of ischemic stroke patients received ...
There have been relatively few community-based studies of long-term prognosis after acute stroke. This study aimed to provide precise estimates of the absolute and relative risks of dying in an unselected cohort of patients with a first-ever stroke.. Six hundred seventy-five patients were registered by a community-based stroke register (the Oxfordshire Community Stroke Project) and prospectively followed up for up to 6.5 years. Their relative risk of death was calculated using age- and sex-specific mortality rates for Oxfordshire.. During the first 30 days, 129 (19%) patients died. Patients who survived at least 30 days after a first-ever stroke thereafter had an average annual risk of death of 9.1%, 2.3-fold the risk in people from the general population. Although the absolute (about 15%) and relative (about threefold) risks of death were highest in these 30-day survivors over the first year after the stroke, they were at increased risk of dying over the next few years (range of relative risk ...
In 2008, the recently founded European Stroke Organisation published its guidelines for the management of ischemic stroke and transient ischemic attack. This highly cited document was translated in several languages and was updated in 2009. Since then, the European Stroke Organisation has published guidelines for the management of intracranial aneurysms and subarachnoidal hemorrhage, for the establishment of stroke units and stroke centers, and recently for the management of intracerebral hemorrhage. In recent years, the methodology for the development of guidelines has evolved significantly. To keep pace with this progress and driven by the strong determination of the European Stroke Organisation to further promote stroke management, education, and research, the European Stroke Organisation decided to delineate a detailed standard operating procedure for its guidelines. There are two important cornerstones in this standard operating procedure: The first is the implementation of the Grading of
TY - JOUR. T1 - Stroke outcome in clinical trial patients deriving from different countries. AU - Ali, Myzoon. AU - Atula, Sari. AU - Bath, Philip M W. AU - Grotta, James. AU - Hacke, Werner. AU - Lyden, Patrick. AU - Marler, John R.. AU - Sacco, Ralph L. AU - Lees, Kennedy R.. PY - 2009/1/1. Y1 - 2009/1/1. N2 - BACKGROUND AND PURPOSE: Stroke incidence and outcome vary widely within and across geographical locations. We examined whether differences in index stroke severity, stroke risk factors, mortality, and stroke outcome across geographical locations remain after adjusting for case mix. METHODS: We analyzed 3284 patients from the Virtual International Stroke Trials Archive (VISTA). We used logistic regression to examine the incidence of mild index stroke, functional, and neurological outcomes after accounting for age, medical history, year of trial recruitment, and initial stroke severity in the functional and neurological outcome analyses. We examined mortality between geographical regions ...
At least half of childhood stroke survivors suffer long-term impairments. Rapid identification of stroke is essential to minimize the extent of injury by restoring perfusion to viable brain. Improving diagnosis of childhood stroke requires correct identification of stroke by prehospital and emergency physicians, rapid performance of appropriate neuroimaging to confirm infarction, and targeted investigations to determine underlying causes, which guide treatment decisions to reduce recurrence risk. Areas covered: This review will summarize the barriers to rapid stroke diagnosis in pre-hospital and emergency department settings, describe recent progress in understanding of the spectrum, presenting clinical features and differential diagnosis of childhood stroke, discuss clinical stroke recognition tools which improve diagnostic accuracy, and their application to children ...
Der ischämische Schlaganfall ist ein ernstzunehmendes Ereignis, welches rascher Rekanalisationstherapie bedarf. Hierfür stehen mehrere Therapieansätze zur Verfügung. Bildgebungsgestützte Patientenselektion zur individuell geeigneten Therapie kann das abschließende klinische Behandlungsergebnis des einzelnen Patienten maßgeblich verbessern. Der Alberta Stroke Program Early CT Score (ASPECTS), eine einfach und schnell anwendbare 10-Punkte-Skala zur Auswertung von Schädel-CT-Untersuchungen, wurde bereits als hilfreicher Prädiktor für das klinische Behandlungsergebnis nach erfolgreicher thrombolytischer Therapie identifiziert. Ein Nachteil der nativen Schädel-CT ist, dass der Infarktkern erst mit mehreren Stunden Verzögerung erkennbar wird. Das aktuelle Ausmaß des Infarktkerns kann durch Bestimmung des zerebralen Blutvolumens (CBV) anhand von Perfusions-CT-Untersuchungen schneller ermittelt werden. Diese Studie analysiert retrospektiv multimodale CT-Bildgebung einer Patientenkohorte von ...
TY - JOUR. T1 - Routine Troponin Measurements Are Unnecessary to Exclude Asymptomatic Coronary Events in Acute Ischemic Stroke Patients. AU - Ali, Farwa. AU - Young, Jimmy. AU - Rabinstein, Alejandro. AU - Flemming, Kelly. AU - Fugate, Jennifer E.. PY - 2016/5/1. Y1 - 2016/5/1. N2 - Background Obtaining serum troponin levels in every patient with acute stroke is recommended in recent stroke guidelines, but there is no evidence that these contribute positively to clinical care. We sought to determine the clinical significance of measuring troponin levels in acute ischemic stroke patients. Methods We reviewed 398 consecutive patients with acute ischemic stroke at a large academic institution from 2010 to 2012. Troponin levels were measured as a result of protocol in place during part of the study period. The mean age was 70 years (standard deviation ±16 years) and 197 (49.5%) were men. Results Chronic kidney disease was present in 78 (19.6%), coronary artery disease in 107 (26.9%), and atrial ...
1. Previous studies have indicated that increases in dietary K+ promote diuresis and retard stroke development in stroke-prone spontaneously hypertensive rats (spSHR) fed a Japanese-style diet containing 4% NaCl.. 2. It is possible that elevations in dietary K+ retard stroke development by inducing natriuresis and facilitating the clearance of Na+, and that diuretics associated with natriuresis might also be capable of retarding stroke development in spSHR. To test if this was the case, the onset of stroke development in spSHR fed a low (0.75%) K+ diet containing 4% NaCl (controls) was monitored and compared with that in spSHR treated with (a) frusemide, (b) chlorothiazide, (c) amiloride or (d) acetazolamide, and with (e) untreated spSHR fed a high (2.11%) K+ diet.. 3. The onset of stroke, as well as death resulting from stroke, occurred at a significantly later age in spSHR fed a high K+ diet than in spSHR fed a low-K+ diet, despite the fact that both groups of spSHR rats had comparable blood ...
Cardioembolic strokes were particularly disabling (p = 0.05). Efficient tools that discriminate cardioembolic from noncardioembolic strokes may improve care as anticoagulation is frequently indicated after cardioembolism. However, a substantial number of ischemic strokes in NVAF patients are related to non-CE mechanisms. The risk of stroke is increased in patients with previous transient ischemic attacks (TIAs) such that to avoid recurrence, practicing an appropriate secondary prevention strategy is pivotal. By continuing you agree to the use of cookies. / Hart, R. G.; Pearce, L. A.; Miller, V. T.; Anderson, D. C.; Rothrock, J. F.; Albers, G. W.; Nasco, E. T1 - Cardioembolic vs. noncardioembolic strokes in atrial fibrillation, T2 - Frequency and effect of antithrombotic agents in the stroke prevention in atrial fibrillation studies. Together they form a unique Conclusions: Most ischemic strokes in AF patients are probably cardioembolic, and these are sharply reduced by adjusted-dose warfarin. R. ...
Estimated 10-Year Stroke Risk by Region and Race in the United States Mary Cushman, MD, MSc,1 Ronald A. Cantrell, PhD,2 Leslie A. McClure, PhD,3 George Howard, DrPH,3 Ronald J. Prineas, MD, PhD,4 Claudia S. Moy, PhD,5 Ella M. Temple, PhD,3 and Virginia J. Howard, PhD2 Objective: Black individuals younger than 75 years have more than twice the risk for stroke death than whites in the United States. Regardless of race, stroke death is approximately 50% greater in the stroke belt and stroke buckle states of the Southeastern United States. We assessed geographic and racial differences in estimated 10-year stroke risk. Methods: The Reasons for Geographic and Racial Differences in Stroke study is a population-based cohort of men and women 45 years or older, recruited February 2003 to September 2007 at this report, with oversampling of stroke belt/buckle residents and blacks. Racial and regional differences in the Framingham Stroke Risk Score were studied in 23,940 participants without previous ...
The rapid diagnosis and treatment of acute ischemic stroke are critical in the reduction of morbidity, disability and stroke associated mortality Under-education about stroke may prevent people from recognizing symptoms early enough to seek immediate care.. The studies reported on stroke patients managed in stroke center have shown that 39-42% of patients could not name any symptoms of stroke and 36% to 43% no risk factor of stroke.. The stroke patients are therefore a population at high risk for neurological events and cardiac vascular recurrence. However, no studies have evaluated the interest of the development of therapeutic workshops in stroke unit to educate patients about symptoms suggestive of stroke, risk factors and what to do in cases of stroke.. Investigators assume that the setting up of a therapeutic education workshop in the stroke unit may allow a better understanding of the symptoms, risk factors and what to do following stroke. So there is a direct benefit to the patient ...
article{3f0ddea8-dd33-4fdd-a777-97a29bef9f47, abstract = {Stroke outcome is determined by a complex interplay, where age and stroke severity are predominant predictors. Studies on hemorrhagic stroke indicate that APOE genotype is a predictor of poststroke outcomes,1,2 but results from studies on ischemic stroke are more conflicting.1,3 There is 1 study suggesting an influence of APOE genotype on age at ischemic stroke onset,4 and sex-specific effects on outcome have been reported.5 Taken together, there is a need for larger studies on APOE and ischemic stroke outcomes with integrated information on age, severity, and sex.,br/,,br/,The 3 common APOE alleles ε2, ε3, and ε4 can be separated by a combination of 2 single nucleotide polymorphisms (SNPs), rs429358 and rs7412. Thus, associations with APOE alleles are not directly captured in a regular genome-wide association study (GWAS), where each SNP is investigated separately. We derived the 3 common APOE alleles and investigated the interplay ...
Background: Given the limited time window available for treatment with tPA in acute ischemic stroke patients, guidelines recommend door-to-imaging time within 25 minutes of hospital arrival and a door-to-needle time (DTN) within 60 minutes. Despite temporal improvements in door-to-image and DTN, tPA treatment times remain suboptimal.. Objectives: To examine the contributions of door-to-image and imaging-to-needle times to delays in timely delivery of tPA to ischemic stroke patients, and to examine between-hospital variation in DTN.. Methods: A cohort analysis of 1,193 ischemic stroke patients treated with intravenous tPA from 2009-2012 at 25 Michigan hospitals participating in the Paul Coverdell National Acute Stroke Registry. The primary outcome was DTN (time in minutes from emergency department arrival to tPA delivery). Multi-level linear regression models included hospital-specific random effects.. Results: Mean patient age was 68 years, median NIHSS score was 11 (IQR 6-17), 51% were female, ...
OBJECTIVE: To investigate the influence of prestroke physical activity (PA) on acute stroke severity.. METHODS: Data from patients with first stroke were retrieved from registries with a cross-sectional design. The variables were PA, age, sex, smoking, diabetes, hypertension and statin treatment, stroke severity, myocardial infarction, new stroke during hospital stay, and duration of inpatient care at stroke unit. PA was assessed with Saltin-Grimbys 4-level Physical Activity Level Scale, and stroke severity was assessed with the National Institutes of Health Stroke Scale (NIHSS). Logistic regression was used to predict stroke severity, and negative binomial regression was used to compare the level of PA and stroke severity.. RESULTS: The study included 925 patients with a mean age of 73.1 years, and 45.2% were women. Patients who reported light or moderate PA levels were more likely to present a mild stroke (NIHSS score 0 to 5) compared with physically inactive patients in a model that also ...
MUDZI, W; STEWART, A and MUSENGE, E. Case fatality of patients with stroke over a 12-month period post stroke. SAMJ, S. Afr. med. j. [online]. 2012, vol.102, n.9, pp.765-767. ISSN 2078-5135.. INTRODUCTION: Stroke is among the top 4 causes of death in South Africa and the top 10 leading causes of disability worldwide. There is a dearth of literature on stroke incidence, prevalence and outcome in sub-Saharan Africa. We aimed to establish the case fatality of stroke patients over a 12-month period post discharge from hospital. METHODS: A total of 200 patients with first-time ischaemic stroke were recruited from Chris Hani Baragwanath Academic Hospital and followed up for 12 months. The Barthel Index (BI) and Rivermead Mobility Index (RMI) were used to establish patient functional ability and, by inference, stroke severity. Follow-up assessments were performed at 3, 6 and 12 months post discharge. Data analysis was largely descriptive in nature. RESULTS: Thirty-eight per cent of patients died within ...
Background: Nationwide data on the clinical profile and outcomes of ischemic stroke in younger adults are still scarce. Our aim was to analyze clinical characteristics and outcomes of young patients with first-ever ischemic stroke compared to older patients.Methods: The National Acute Stroke ISraeli (NASIS) registry is a nationwide prospective hospital-based study performed triennially. Younger adults, aged 50 years and younger, were compared with patients, aged 51-84 years regarding risk factors, clinical presentation, stroke severity, stroke etiology and outcomes. A logistic model for stroke outcome was fitted for each age group. Results: 336 first-ever ischemic strokes were identified among patients aged 50 years and younger and 3,243 among patients 51-84 years. Younger adults had lower rates of traditional vascular risk factors, but 82.7% had at least one of these risk factors. Younger adults were more likely to be male (62.8%), current smokers (47.3%), and to have a family history of stroke (7.4%).
After a patient has a stroke, physicians must begin treatment as quickly as possible to minimize damage. Researchers at Cornell Universitys Baker Institute for Animal Health, have developed a stroke diagnosis device that takes only ten minutes and a small drop of the patients blood to generate a result.. Currently, stroke diagnosis takes up to three hours and requires skilled technicians to perform the lab work. These are hours that stroke victims could be receiving treatment, as earlier intervention has been shown to lead to better outcomes.. The study - which was published in the journal, PLOS One - demonstrated the proof of principal for the medical diagnostic device. The researchers say with further development, the tool could be used in hospital emergency rooms to diagnose stroke along with other conditions such as concussion, dementia and even heart disease and cancer.. According to Roy Cohen, a Research Scientist at the Baker Institute, and the studys lead author, the technology ...
TY - JOUR. T1 - Incidence, Predictors, and Outcomes of Acute Ischemic Stroke Following Percutaneous Coronary Intervention. AU - Alkhouli, Mohamad. AU - Alqahtani, Fahad. AU - Tarabishy, Abdulrahman. AU - Sandhu, Gurpreet. AU - Rihal, Charanjit S.. PY - 2019/8/12. Y1 - 2019/8/12. N2 - Objectives: The aim of this study was to assess temporal trends in the incidence of ischemic stroke among patients undergoing percutaneous coronary intervention (PCI), predictors of post-PCI ischemic stroke, and the impact of post-PCI ischemic stroke on in-hospital morbidity, mortality, length of stay, and cost. Background: Data on the incidence and outcomes of ischemic stroke in patients undergoing PCI in the contemporary era are limited. Methods: The National Inpatient Sample was used to identify patients who underwent PCI between January 1, 2003, and December 31, 2016. The incidence of post-PCI ischemic stroke was calculated, and its predictors were assessed. In-hospital outcomes of patients with and those ...
TY - JOUR. T1 - Performance and Training Standards for Endovascular Ischemic Stroke Treatment. AU - Meyers, Philip M.. AU - Schumacher, H. Christian. AU - Alexander, Michael J.. AU - Derdeyn, Colin P.. AU - Furlan, Anthony J.. AU - Higashida, Randall T.. AU - Moran, Christopher J.. AU - Tarr, Robert W.. AU - Heck, Donald V.. AU - Hirsch, Joshua A.. AU - Jensen, Mary E.. AU - Linfante, Italo. AU - McDougall, Cameron. AU - Nesbit, Gary M.. AU - Rasmussen, Peter A.. AU - Tomsick, Thomas A.. AU - Wechsler, Lawrence R.. AU - Wilson, John R.. AU - Zaidat, Osama O.. PY - 2009/11/1. Y1 - 2009/11/1. N2 - Stroke is the third-leading cause of death in the United States, Canada, Europe, and Japan. According to the American Heart Association and the American Stroke Association, 750,000 new strokes occur each year, resulting in 200,000 deaths (or 1 of every 16 deaths) per year in the United States alone. Endovascular therapy for patients with acute ischemic stroke is an area of intense investigation. The ...
Introduction: The detection and interpretation of early ischemic changes and salvageable brain parenchyma in acute ischemic stroke is critical in determining appropriate treatment. The Alberta Stroke Program Early CT Score (ASPECTS) was devised as a semi-quantitative method to accurately and reliably determine early ischemic changes in non-contrast CT (NCCT) and CT-perfusion (CTP) imaging. Our objective was to determine the inter-observer variability In assigning ASPECTS to admission NCCT, CTP, and follow-up imaging. Methods: A retrospective study was performed of imaging and clinical data obtained for ischemic stroke patients admitted to the MUSC stroke center between October 1, 2008 - September 30, 2009. Patients were included in the study if they: received a good quality CT and CTP at admission and follow-up NCCT and/or MRI within 7 days, had a National Institute of Health Stroke Scale (NIHSS) score ~ 8 at admission, and were ~ 45 years old. Patients were excluded if they: received a primary ...
RATIONALE: Recurrent stroke is prevalent in both developed and developing countries, contributing significantly to disability and death. Recurrent stroke rates can be reduced by adequate risk factor management. However, adherence to prescribed medications and lifestyle changes recommended by physicians at discharge after stroke is poor, leading to a large number of preventable recurrent strokes. Using behavior change methods such as Motivational Interviewing early after stroke occurrence has the potential to prevent recurrent stroke. AIMS AND/OR HYPOTHESIS: The overall aim of the study is to determine the effectiveness of motivational interviewing in improving adherence to medication and lifestyle changes recommended by treating physicians at and after hospital discharge in stroke patients 12 months poststroke to reduce risk factors for recurrent stroke. DESIGN: Recruitment of 430 first-ever stroke participants will occur in the Auckland and Waikato regions. Randomization will be to intervention or
Stroke is a major cause of disability and the long-term effects of stroke often lead to need of rehabilitation services. It has been shown that intensive stroke unit care and functional exercises are beneficial in the acute rehabilitation of stroke. The duration of the rehabilitation of patients with acute stroke is decreasing, leaving patients with not complete recovery at discharge in need of follow-up services. There is a general assumption that physical exercises are beneficial at all stages of stroke but it is questionable if these benefits are sustained after treatment ends. There are, to our knowledge, no longitudinal studies of non-interrupted regular physical exercises from the acute phase till one year post stroke.. The purpose of this project is to follow first-ever- acute stroke patients from onset, one, two and four years post stroke. All acute stroke patients will be treated in a stroke unit and the physiotherapy treatment will be according to Motor Relearning Programme principles ...
Antiplatelet therapy for acute ischaemic stroke.. Cochrane Database Syst Rev. 2008;(3):CD000029. Authors: Sandercock PA, Counsell C, Gubitz GJ, Tseng MC. BACKGROUND: In patients with acute ischaemic stroke, platelets become activated. Antiplatelet therapy might reduce the volume of brain damaged by ischaemia and reduce the risk of early recurrent ischaemic stroke. This might reduce the risk of early death and improve long-term outcome in survivors. However, antiplatelet therapy might also increase the risk of fatal or disabling intracranial haemorrhage. OBJECTIVES: To assess the efficacy and safety of antiplatelet therapy in acute ischaemic stroke. SEARCH STRATEGY: We searched the Cochrane Stroke Group Trials Register (last searched June 2007), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 2, 2007), MEDLINE (June 1998 to May 2007), and EMBASE (June 1998 to May 2007). In 1998, for a previous version of this review, we searched the register of the ...
University of Glasgow. About stroke. Approximately 150,000 people suffer a stroke in the UK each year. The vast majority of these strokes are ischaemic in nature, caused by a blockage of blood flow in the brain (as opposed to a haemorrhagic or bleeding stroke). Approximately one half of all stroke survivors are left with permanent disabilities as a result of the damage caused to brain tissue arising from the stroke. The annual health and social costs of caring for these patients is estimated to be in excess of £5 billion in the UK, with stroke patients estimated to be occupying at least 25 per cent of long term hospital beds.. The only current treatment for ischaemic stroke patients occurs in the acute phase of the condition (within several hours of the stroke), when anti-clotting agents are administered to dissolve the clot causing the blockage in blood flow to the brain. Only a small proportion of patients get to the hospital in time to be treated in this way.. Beyond the acute phase, there ...
© 2015 World Stroke Organization. Background: Aspirin is of moderate overall benefit for patients with acute disabling ischemic stroke. It is unclear whether functional outcome could be improved after stroke by targeting aspirin to patients with a high risk of recurrent thrombosis or a low risk of haemorrhage. Aims: We aimed to determine whether patients at higher risk of thrombotic events or poor functional outcome, or lower risk of major haemorrhage had a greater absolute risk reduction of poor functional outcome with aspirin than the average patient. Methods: We used data on individual ischemic stroke patients from three large trials of aspirin vs. placebo in acute ischemic stroke: the first International Stroke Trial (n=18372), the Chinese Acute Stroke Trial (n=20172) and the Multicentre Acute Stroke Trial (n=622). We developed and evaluated clinical prediction models for the following: early thrombotic events (myocardial infarction, ischemic stroke, deep vein thrombosis and pulmonary embolism);
Higher body temperature is a prognostic factor of poor outcome in acute stroke. Our aim was to study the relationship between body temperature, HT (haemorrhagic transformation) and biomarkers of BBB (blood-brain barrier) damage in patients with acute ischaemic stroke untreated with rtPA (recombinant tissue-type plasminogen activator). We studied 229 patients with ischaemic stroke ,12 h from symptom onset. Body temperature was determined at admission and every 6 h during the first 3 days. HT was evaluated according to ECASS II (second European Co-operative Acute Stroke Study) criteria in a multimodal MRI (magnetic resonance imaging) at 72 h. We found that 55 patients (34.1%) showed HT. HT was associated with cardioembolic stroke (64.2% against 23.0%; P,0.0001), higher body temperature during the first 24 h (36.9°C compared with 36.5°C; P,0.0001), more severe stroke [NIHSS (National Institutes of Health Stroke Scale) score, 14 (9-20) against 10 (7-15); P=0.002], and greater DWI ...
It is an object of the invention to present an input and display apparatus for handwritten characters capable of freely editing input handwritten characters. A handwritten character entered on a touch panel by using a pen is registered as one stroke data. The registered one stroke data is divided in two stroke data by using the pen, or two stroke data are combined into one stroke data. By combination of stroke data division and combination, partial deletion in stroke data, blank insertion in stroke data, and insertion of other stroke data into stroke data are realized.
We use experimental models to understand the short-term and long term consequences of ischemic stroke, and our goal is to develop stroke therapies, using compounds that can modify the brain and immune system, to improve stroke recovery.. We are especially interested in sex differences in stroke. Young females are less likely to experience a stroke as compared to young males. However, after the age of 50+, women are equally likely to suffer a stroke as compared to men. At older ages, many more women will get a stroke as compared to men, and their stroke are likely to be worse, resulting in greater mortality, disability and loss of independence. Women are also more likely to exhibit post-stroke depression.. Stroke outcomes can be modified by environmental and developmental factors, and in turn stroke can also lead to other disabilities, such as epilepsy, addiction, depression. In conjunction with our colleagues at the TAMHSC COM and TAMIN, we are studying these issues in an animal model.. Stroke ...
BACKGROUND AND PURPOSE Ischemic stroke has a strong familial component to risk. The Siblings With Ischemic Stroke Study (SWISS) is a genome-wide, family-based analysis that included use of imputed genotypes. The Siblings With Ischemic Stroke Study was conducted to examine the associations between single-nucleotide polymorphisms (SNPs) and risk of stroke and stroke subtypes within pairs. METHODS The Siblings With Ischemic Stroke Study enrolled 312 probands with ischemic stroke from 70 US and Canadian centers. Affected siblings were ascertained by centers and confirmed by central record review; unaffected siblings were ascertained by telephone contact. Ischemic stroke was subtyped according to Trial of Org 10172 in Acute Stroke Treatment criteria. Genotyping was performed with an Illumina 610 quad array (probands) and an Illumina linkage V array (affected siblings). SNPs were imputed by using 1000 Genomes Project data and MACH software. Family-based association analyses were conducted by using the
To the best of our knowledge, this is the first report of an association between the location of acute infarcts and PSF outcome. The main finding is that subcortical white matter infarcts are associated with persistent fatigue 15 months after the index stroke in patients with well-established stroke.. A few studies have evaluated the possible impact of lesion location on PSF at the chronic stage of stroke, with negative results. Schepers et al. [25] did not find any association between laterality or type of stroke (ischemic vs haemorrhagic) and PSF at 1 year poststroke in 167 stroke patients [2]. Another study on 253 patients also found that stroke type was not related PSF at 1 year poststroke [6]. No association was found between PSF at 1.5 years poststroke and lesion location or white matter hyperintensities [3], and no relationship was found between lesion site and PSF 1 year poststroke in 99 stroke survivors [4]. Type or laterality of stroke was not related to increased fatigue in 242 ...
A stroke is a serious, life-threatening medical condition that occurs when the blood supply to part of the brain is cut off.. Strokes are a medical emergency and urgent treatment is essential because the sooner a person receives treatment for a stroke, the less damage is likely to happen.. Salford Royal is the Comprehensive Stroke Centre for the Greater Manchester Clinical Stroke Network.. Our Acute Stroke Unit, which treats people as soon as possible after symptoms start, has been providing specialist life-saving treatment for patients from across Greater Manchester since 2004.. Stroke research is an important part pf the stroke services at Salford and a wide range of studies involving stroke and the emergency conditions affecting the brain take place here.. The research we carry out looks at the causes and treatment of stroke. We are also interested in bleeding that happens in the brain tissue (intracerebral haemorrhage) and within the area around the brain (subarachnoid haemorrhage). The ...
Diagnosis and treatment of acute stroke has advanced considerably in the past 2 decades. Most notably, in cases of ischemic stroke, intravenous alteplase has become the standard of medical treatment despite its multiple contraindications and limited time window. More recently, trials have proven that endovascular thrombectomy is superior to medical therapy alone, advancing the standard of care for patients who present with acute ischemic stroke from a large vessel occlusion and salvageable brain tissue. The treatment of hemorrhagic stroke now involves the use of novel pharmacological agents and advanced minimally invasive technology. Important changes have also occurred at the levels of hospital organization and treatment decision-making. Such changes in organization and designation of hospitals with distinct levels of stroke care and the variety of stroke protocols now requires team work of emergency medical services (EMS), Emergency Department, stroke neurologists, neurosurgeons, and
Background: Continuous changes in stroke treatment and care, as well as changes in stroke characteristics, may alter stroke outcome over time. The aim of this paper is to describe time trends for treatment and outcome data, and to discuss if any such changes could be attributed to quality changes in stroke care. Methods: Data from Riks-Stroke, the Swedish stroke register, were analyzed for the time period of 1995 through 2010. The total number of patients included was 320,181. The following parameters were included: use of computed tomography (CT), stroke unit care, thrombolysis, medication before and after the stroke, length of stay in hospital, and discharge destination. Three months after stroke, data regarding walking, toileting and dressing ability, as well social situation, were gathered. Survival status after 7, 27 and 90 days was registered. Results: In 1995, 53.9% of stroke patients were treated in stroke units. In 2010 this proportion had increased to 87.5%. Fewer patients were ...
Our Commitment to Stroke Care. After a stroke, every second counts. Strokes happen when a clot blocks a blood vessel in the brain or when a blood vessel bursts. Without a constant blood supply, brain cells quickly die. In fact, nearly 2 million brain cells are lost every minute after a stroke starts. According to The American Heart Association/American Stroke Association, stroke is the No. 5 cause of death and a leading cause of adult disability in the United States. On average, someone in the U.S. suffers a stroke every 40 seconds and nearly 795,000 people suffer a new or recurrent stroke each year. Stroke is a major concern for the community, which is why Memorial Hospital of Gardena has made a significant investment in stroke care. What inspires us, however, are the citizens of Gardena. We believe strongly that it is our duty to offer quality, compassionate, state-of-the-art stroke care to our community. In March 2017, we became the first certified stroke center in Gardena. The Joint ...
HOUSTON, Feb. 22, 2017 - Scientists who have devoted their careers to stroke research and contributed to groundbreaking studies, as well as young stroke researchers making notable contributions to todays understanding of the disease, will be honored for their work by the American Stroke Association during the International Stroke Conference 2017 at the George R. Brown Convention Center in Houston, Texas.
Mercy Hospital and Trauma Center recently received the Get With The Guidelines -Stroke Gold-Plus Quality Achievement Award for implementing specific quality improvement measures outlined by the American Heart Association/American Stroke Association for the treatment of stroke patients. It has also received the Heart Failure Silver-Plus Quality Achievement Award for implementing specific quality improvement measures for heart failure patients.. Get With The Guidelines Stroke helps hospital teams provide the most up-to-date, research-based guidelines with the goals of speeding recovery and reducing death and disability for stroke and heart failure patients. Mercyhealth earned the award by meeting specific quality achievement measures for the rapid diagnosis and treatment of stroke patients at a set level for a designated period. These measures include aggressive use of medications and risk-reduction therapies aimed at reducing death and disability and improving the lives of stroke patients.. Mercy ...
The relation of orthostatic blood pressure decrease, or increase, with occurrence of ischemic stroke subtypes has not been examined. We investigated the association of orthostatic blood pressure change (within 2 minutes after supine to standing) obtained at baseline (1987 to 1989) in the Atherosclerosis Risk in Communities Study with incidence of ischemic stroke subtypes through 2007. Among 12 817 black and white individuals without a history of stroke at baseline, 680 ischemic strokes (153 lacunar, 383 nonlacunar thrombotic, and 144 cardioembolic strokes) occurred during a median follow-up of 18.7 years. There was a U-shaped association between orthostatic systolic blood pressure change and lacunar stroke incidence (quadratic P=0.004). In contrast, orthostatic systolic blood pressure decrease of 20 mm Hg or more was associated with increased occurrence of nonlacunar thrombotic and cardioembolic strokes independent of sitting systolic blood pressure, antihypertensive medication use, diabetes, ...
Learn more about the American Stroke Association and its efforts to reduce death and disability caused by stroke. Also learn about types of stroke, stroke warning signs, how to avoid stroke, find information to enhance the quality of life for stroke survivors, resources for healthcare professionals, and more.
We retrospectively compared the acute ASPECTSs on noncontrast CT, CTA source images, and CT perfusion CBV maps from a cohort of confirmed nonlacunar MCA strokes imaged within 3 hours of symptom onset that had angiographic proof of recanalization. There is no prior study, to our knowledge, that has evaluated the accuracy of ASPECTS on all 3 techniques during this early period of hyperacute stroke. Our results confirm the generally accepted notion that in acute cerebral ischemia, regions of hypoattenuation on noncontrast CT and CTA source images and hypoperfusion on CT perfusion CBV maps represent unsalvageable tissue despite reperfusion.19,20 However, in the 3-hour window, CBV appears to be a significantly more sensitive and accurate marker for irreversible ischemic damage. We compared the mean ASPECTS of each CT-based technique and found no difference between the scores on noncontrast CT and CTA source images, but both were different from scores on CT perfusion CBV maps. Compared with the mean ...
TY - JOUR. T1 - Long-Term Exposure to Air Pollution and Survival After Ischemic Stroke. T2 - The China National Stroke Registry Cohort. AU - Chen, Gongbo. AU - Wang, Anxin. AU - Li, Shanshan. AU - Zhao, Xingquan. AU - Wang, Yilong. AU - Li, Hao. AU - Meng, Xia. AU - Knibbs, Luke D.. AU - Bell, Michelle L.. AU - Abramson, Michael J.. AU - Wang, Yongjun. AU - Guo, Yuming. PY - 2019/3/1. Y1 - 2019/3/1. N2 - Background and Purpose- China bears a heavy burden of stroke because of its large population of elderly people and the propensity for stroke. Previous studies have examined the association between air pollution and stroke mortality or hospital admission. However, the global evidence for adverse effects of air pollution on survival after stroke is scarce. Methods- We used the first national hospital-based prospective registry cohort of stroke in China, which included 12 291 ischemic stroke patients who visited hospitals during 2007 to 2008. All patients were followed for 1-year poststroke. Deaths ...
According to the Center for Disease Control someone suffers a stroke every 45 seconds of the day. This translates into more than 780,000 strokes annually in the United States alone, with someone dying every 3.3 minutes; costing more than $53.9 billion each year for the treatment of stroke victims. It is the fourth leading cause of death and the primary cause of adult disability in the United States.. The vision to create a stroke network began in 1999, when only about half of the hospitals in South Florida were performing CT scans on a 24/7 basis. The scans are necessary to administer the clot-dissolving drug TPA (tissue plasminogen activator). To expedite treatment, South Floridas firefighters, doctors and local hospitals have collaborated to create one of the largest stroke consortiums in the nation called FOAM-D Stroke Consortium.. Under the Stroke Network, hospitals are designated as either a Primary or Comprehensive stroke center. Primary facilities are able to provide care to stroke ...
Barb McGrath, R.N., FirstHealth of the Carolinas stroke coordinator and Melanie Blacker, M.D., FirstHealth Stroke Center medical director, accept the American Heart Association and American Stroke Association Get With The Guidelines® award.. PINEHURST-FirstHealth Moore Regional Hospital has been awarded the American Heart Association and American Stroke Association Get With The Guidelines® Stroke Gold Plus Performance Achievement Award and Target Stroke Elite Plus Honor Roll. The awards recognize the hospitals commitment to ensuring stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines according to the latest scientific evidence.. The FirstHealth service area is in the stroke belt where the incidence of stroke is higher than in other areas of the country. North Carolina is ranked the 6th highest state for stroke mortality, 23% higher than the US rate. In the past 10 years (2008 to 2018), the number of stroke patients treated at ...
Burton J. Tabaac, MD. Join the fight against stroke! In 2015, the World Stroke Campaign focused on raising awareness of stroke prevention and risk among women using the tagline I am Woman - Stroke Affects Me, Stroke Affects Everyone. In 2016, World Stroke Day was marked by recognizing that although stroke is a complex medical issue, there are ways to significantly reduce its impact. The World Stroke Organization built a campaign to underscore that Stroke is Treatable. The World Stroke Day 2017 campaign focused on risk awareness and prevention. Last year, World Stroke Day 2018 emphasized that there are resources and a network to assist those who have suffered from stroke, underscoring that you are not in it alone. #UpAgainAfterStroke was used as a rallying cry to inform the public about the well-developed network for caregivers, families, and friends affected by stroke who can help their loved ones. This year, 2019, calls attention to prevention.. A stroke diagnosis is a common and ...
In this multiethnic population of patients with stroke with long-term follow-up, we found significant associations of SED with many provisions of acute and long-term stroke care. More indicators of stroke care seemed to be inversely related to SED in black patients than in white patients. There were more inequalities in stroke care in those whose stroke occurred before 2001.. To our knowledge the current study is the first to compare SED impact on stroke care between white patients and black patients who live in high-income countries. The SLSR data includes the largest proportion of black and minority ethnicity patients in the world. Although living in the same society in the UK, black people generally have lower levels of education and occupational class and are poorer than white people. These offered a unique opportunity for us to identify the association of SED with stroke care. A second strength is that our study covered a long time period, with meticulous follow-up of the patients with ...
TY - JOUR. T1 - Childhood stroke and supraventricular tachycardia. AU - Atluru, Vijaya L.. AU - Epstein, Leon G.. AU - Gootman, Norman. PY - 1985/1/1. Y1 - 1985/1/1. N2 - Acquired hemiplegia in childhood is uncommon. All causes of stroke in adults should be considered in children, including atherosclerotic cerebrovascular disease even though it is rare. In addition, children suffer from many conditions that may result in stroke. Unlike adults, a cardiac illness resulting in stroke is extremely unusual in an otherwise healthy child. We report a case of a four-year-old child; he presented with the sudden onset of a right hemiplegia associated with supraventricular tachycardia. Cerebral angiography indicated a left internal carotid artery occlusion. To our knowledge this is the first reported case of childhood stroke with supraventricular tachycardia (SVT).. AB - Acquired hemiplegia in childhood is uncommon. All causes of stroke in adults should be considered in children, including atherosclerotic ...
2) hemorrhagic stroke takes place when an artery ruptures or leaks.. Both types of strokes can be misdiagnosed and lead to serious, permanent injuries. Similar to the misdiagnosis of a heart attack, the symptoms of a stroke may mimic other less serious conditions.. However, thats no excuse for stroke medical errors or misdiagnosis. The Joint Commission in conjunction with the American Stroke Association has developed a training and certification program for hospitals and medical facilities. They provide training and education for medical professionals as well as certification programs so that hospitals and urgent care facilities are able to recognize the early warning signs and symptoms of a stroke as well as proper training for the care of stroke victims.. While the onset of a stroke may occur at any moment, its important to know which hospitals in your area are certified by the American Stroke Association and the Joint Commission. If youre interested in determining which health facilities ...
TY - JOUR. T1 - Nationwide Frequency and Association of Heart Failure on Stroke Outcomes in the United States. AU - Divani, Afshin A. AU - Vazquez, Gabriela. AU - Asadollahi, Marjan. AU - Qureshi, Adnan I. AU - Pullicino, Patrick. PY - 2009/2/1. Y1 - 2009/2/1. N2 - Background: Few studies of the effect of heart failure (HF) on stroke outcomes have been published. This study was designed to determine the association of co-existing HF with in-hospital length-of-stay (LOS), cost, and mortality among acute stroke patients admitted to hospitals in the United States (US). Methods and Results: All patients with a primary diagnosis of stroke admitted to the US hospitals in calendar years 1995 and 2005 were extracted using the National Inpatient Sample (NIS) database. Patients were categorized based on a secondary diagnosis of HF. Patients demographics, LOS, in-hospital death, disposition, and hospitalization costs were determined. The odds ratio of in-hospital mortality rates for stroke patients with ...
by Davide Strambo. In these exciting years of continuous innovations in stroke care, there is something never changing: stroke is a clinical-based diagnosis and we dont have to be too confident on MRI: DWI-NEGATIVE STROKE: A SYSTEMATIC REVIEW AND META-ANALYSIS OF FREQUENCY AND OUTCOMES (R. Gurney et al.) remind us that some ischemic strokes (about 9%) have no lesion on DWI.. However, stroke medicine still has many areas of uncertainty, as we can see in the poster session on NEUROINTERVENTION - EXCLUDING CLINICAL TRIAL RESULTS. Here great attention was given to mechanical thrombectomy for posterior circulation strokes:. the ENDOVASCULAR RECANALIZATION IN POSTERIOR CIRCULATION STROKE WITH ASPIRATION DEVICES IS FASTER, EFFECTIVE AND NOT DETRIMENTAL TO OUTCOME COMPARED TO STENT RETRIEVER DEVICES: THE NORDICTUS REGISTRY (de la Riva et al.) showed excellent procedural results (speed and rate of recanalization) with aspiration devices. From the results of MECHANICAL THROMBECTOMY FOR BASILAR ARTERY ...
So, if youre reading this, you are wondering about strokes. Either you, one of your parents or other loved one has had a stroke and you want answers. You may be a doctor and, like me you have been struck with the revelation that in the past 50 years we have made virtually no advances in either the immediate management of stroke victims or any impact on diminishing the long term deficits which so profoundly affect the lives of these patients and their families. Your questions could and, in fact, should include:. What causes a stroke?. What kinds of strokes are there?. How can I prevent a stroke?. What happens in the Emergency Room when a new stroke patient is admitted?. What should be done in the Emergency Room when a new stroke is admitted?. What can be done if I or my loved one has a stroke?. Is the damage permanent?. What can stroke rehabilitation do for a stroke patient?. And for physicians, What is the neuropharmacology of a stroke?. These questions will be answered in ...
A silent stroke is a stroke that does not have any outward symptoms associated with stroke, and the patient is typically unaware they have suffered a stroke. Despite not causing identifiable symptoms a silent stroke still causes damage to the brain, and places the patient at increased risk for both transient ischemic attack and major stroke in the future. In a broad study in 1998, more than 11 million people were estimated to have experienced a stroke in the United States. Approximately 770,000 of these strokes were symptomatic and 11 million were first-ever silent MRI infarcts or hemorrhages. Silent strokes typically cause lesions which are detected via the use of neuroimaging such as MRI. The risk of silent stroke increases with age but may also affect younger adults. Women appear to be at increased risk for silent stroke, with hypertension and current cigarette smoking being amongst the predisposing factors. These types of strokes include lacunar and other ischemic strokes and minor ...
Genetic determinants of stroke, the leading neurological cause of death and disability, are poorly understood and have seldom been explored in the general population. Our aim was to identify additional loci for stroke by doing a meta-analysis of genome-wide association studies.For the discovery sample, we did a genome-wide analysis of common genetic variants associated with incident stroke risk in 18 population-based cohorts comprising 84 961 participants, of whom 4348 had stroke. Stroke diagnosis was ascertained and validated by the study investigators. Mean age at stroke ranged from 45·8 years to 76·4 years, and data collection in the studies took place between 1948 and 2013. We did validation analyses for variants yielding a significant association (at p|5 × 10(-6)) with all-stroke, ischaemic stroke, cardioembolic ischaemic stroke, or non-cardioembolic ischaemic stroke in the largest available cross-sectional studies (70 804 participants, of whom 19 816 had stroke). Summary-level results of
Synsets for stroke. Synset: stroke.n.01. Synonyms: stroke. Part of Speech: NOUN. Definition: (sports) the act of swinging or striking at a ball with a club or racket or bat or cue or hand. Examples: it took two strokes to get out of the bunker , a good shot requires good balance and tempo , he left me an almost impossible shot Lemmas: stroke shot Hypernym: maneuver Hyponym: baseball_swing break carom cut golf_stroke masse miscue swipe tennis_stroke Antonyms: Synset: throw.n.03. Synonyms: throw. Part of Speech: NOUN. Definition: the maximum movement available to a pivoted or reciprocating piece by a cam. Examples: Lemmas: throw stroke cam_stroke Hypernym: movement Hyponym: instroke outstroke Antonyms: Synset: stroke.n.03. Synonyms: stroke. Part of Speech: NOUN. Definition: a sudden loss of consciousness resulting when the rupture or occlusion of a blood vessel leads to oxygen lack in the brain. Examples: Lemmas: stroke apoplexy cerebrovascular_accident CVA Hypernym: attack Hyponym: ...
Stroke is one of the most common causes of mortality and morbidity worldwide. Hemorrhagic stroke comprises 10-20% of strokes. Here, we present a case report of hemorrhagic stroke that may have been secondary to untreated Obstructive Sleep Apnea (OSA) in a young man with no other cardiovascular risk factors or features of metabolic syndrome. A 32-year-old man was admitted for hemorrhagic stroke. An initial thorough workup for the etiology of stroke was inconclusive. Eventually, a polysomnography was done, which demonstrated OSA suggesting that untreated OSA may have contributed to his stroke. OSA may cause hemorrhagic stroke by nocturnal blood pressure surge. So, all physicians should consider doing polysomnography for unexplained hemorrhagic stroke or in patients at risk. Diagnosing and treating OSA would be critical in preventing hemorrhagic stroke and its recurrences.
TY - JOUR. T1 - Recommendations for the establishment of stroke systems of care. T2 - Recommendations from the American Stroke Associations Task Force on the Development of Stroke Systems. AU - Schwamm, Lee H.. AU - Pancioli, Arthur. AU - Acker, Joe E.. AU - Goldstein, Larry B.. AU - Zorowitz, Richard D.. AU - Shephard, Timothy J.. AU - Moyer, Peter. AU - Gorman, Mark. AU - Johnston, S. Claiborne. AU - Duncan, Pamela W.. AU - Gorelick, Phil. AU - Frank, Jeffery. AU - Stranne, Steven K.. AU - Smith, Renee. AU - Federspiel, William. AU - Horton, Katie B.. AU - Magnis, Ellen. AU - Adams, Robert J.. PY - 2005/3/1. Y1 - 2005/3/1. KW - AHA Policy Recommendations. KW - Brain ischemia. KW - Prevention. KW - Stroke. KW - Therapy. UR - http://www.scopus.com/inward/record.url?scp=20144385363&partnerID=8YFLogxK. U2 - 10.1161/01.CIR.0000154252.62394.1E. DO - 10.1161/01.CIR.0000154252.62394.1E. M3 - Review article. VL - 111. SP - 1078. EP - 1091. JO - Circulation. JF - Circulation. SN - 0009-7322. IS - ...
TY - JOUR. T1 - Social isolation and outcomes post stroke. AU - Boden-Albala, Bernadette. AU - Litwak, E.. AU - Elkind, M. S V. AU - Rundek, T.. AU - Sacco, R. L.. PY - 2005/6/14. Y1 - 2005/6/14. N2 - Objective: To assess the relationship between social isolation and stroke outcomes in a multiethnic cohort. Methods: As part of the Northern Manhattan Stroke Study, the authors prospectively followed a cohort of patients with stroke for 5 years. Baseline data including social isolation were collected. At follow-up, the authors documented outcome events as defined by the first occurrence of myocardial infarction (MI), stroke recurrence, or death. Cox hazard models were used to calculate the hazard ratio (HR, 95% CI) for prestroke predictors of post stroke outcomes. Results: The authors followed 655 ischemic stroke cases for a mean of 5 years. The cohort was 55% women; 17% white, 27% African American, 54% Hispanic; mean age 69 ± 12 years. There were 265 first outcome events. In univariate analysis, ...
Methods: We created the Stroke Prognostication using Age and NIH Stroke Scale (SPAN) index by combining age in years plus NIH Stroke Scale (NIHSS) ≥100. We applied the SPAN-100 index to patients in the NINDS tPA stroke trials (parts I and II) to evaluate its ability to predict clinical response and risk of intracerebral hemorrhage (ICH) after thrombolysis. The main outcome measures included ICH (any type) and a composite favorable outcome (defined as a modified Rankin Scale score of 0 or 1, NIHSS ≤1, Barthel index ≥95, and Glasgow Outcome Scale score of 1) at 3 months. Bivariate and multivariable logistic regression analyses were used to determine the association between SPAN-100 and outcomes of interest. ...
On Sunday May 5th 2019, the Stroke Awareness Foundation (SAF) will host its 8thAnnual Fight Stroke Walk at the San Jose Municipal Rose Garden. This fun filled inspiring event spans generations and brings together families, friends, caregivers and stroke survivors to raise money to fight stroke and improve stroke outcomes through public education and awareness efforts.. Since 2012, our Walk has hosted over 3,500 walkers and grew to include over 80 sponsors. Thanks to your generosity, weve raised over $1,000,000 to educate Santa Clara County citizens on signs and symptoms of stroke and most importantly - what to do in the event of a stroke emergency.. All funds raised for this event stay locally to improve stroke education in Santa Clara County. SAF has implemented an aggressive public outreach targeting Santa Clara County residents via VTA bus advertising, movie theater trailers, print media, outdoor banner display, website and social media. We are making a direct impact in the community with ...
The results suggest that female gender should not be included as an independent stroke/thromboembolism (TE) risk factor in guidelines or risk stratification schemes used in treatment of patients with atrial fibrillation.. The increased risk of stroke and TE in patients with atrial fibrillation depends on additional risk factors, and female sex has been suggested as one such risk factor. The 2010 ESC Guidelines for the management of atrial fibrillation consider female gender a minor risk factor for stroke/TE, and recommend oral anticoagulants for females ,65 years with one additional minor risk factor, and females 65-74 with no additional risk factors. Oral anticoagulants can effectively lower the risk of stroke/TE for patients with atrial fibrillation, but also increase the risk of bleeding disorders and should therefore be given only to patients at high risk of stroke/TE.. The aim of the study was to investigate the association between female gender and stroke/TE in a large nationwide cohort. ...
BACKGROUND: The risk of recurrent stroke is up to 10% in the week after a transient ischaemic attack (TIA) or minor stroke. Modelling studies suggest that urgent use of existing preventive treatments could reduce the risk by 80-90%, but in the absence of evidence many health-care systems make little provision. Our aim was to determine the effect of more rapid treatment after TIA and minor stroke in patients who are not admitted direct to hospital. METHODS: We did a prospective before (phase 1: April 1, 2002, to Sept 30, 2004) versus after (phase 2: Oct 1, 2004, to March 31, 2007) study of the effect on process of care and outcome of more urgent assessment and immediate treatment in clinic, rather than subsequent initiation in primary care, in all patients with TIA or minor stroke not admitted direct to hospital. The study was nested within a rigorous population-based incidence study of all TIA and stroke (Oxford Vascular Study; OXVASC), such that case ascertainment, investigation, and follow-up were
July 12, 2017-An investigation of whether a three-point standardized protocol would improve efficiency and outcomes in the treatment of patients suspected of having an emergent large vessel occlusion (ELVO) who present to a primary stroke center (PSC) was published by Ryan A. McTaggart, MD, et al in Journal of the American Medical Association (JAMA): Neurology (2017;74:793-800). The protocol is based on (1) early notification to the closest comprehensive stroke center (CSC), (2) CTA imaging at the PSC, and (3) electronic image sharing before transfer.. This retrospective cohort study demonstrated that when the PSC protocol was fully executed, the rate of good outcomes doubled and the time from arrival at the PSC to reperfusion at the CSC was almost 1 hour less than that with only partial execution of the protocol. The investigators advised that this protocol can be easily replicated between PSC and CSC partners and may improve stroke care delivery for patients with ELVOs presenting to centers ...
Can a Vegetarian Diet Increase Stroke Risk? Fake Meat Burgers Are the Same as Dog Food? Should Everyone Be Screened for Hepatitis C? Help with Sleepless Toddlers! Whats the Real Deal with Cold-Pressed Skin Care and Spray-On Skin? Is Your Mouthwash ...
A STROKE IN INFANT and STROKE IN CHILDREN support and nonprofit group offering information on In Utero Stroke, Infant Stroke, Intrauterine Stroke, Neonatal Stroke along with Hypotonia, Hemiplegia, Hemiparesis, Epilepsy and Hemiplegic Cerebral Palsy
Stroke is amongthe leading causes of death worldwide and requires immediate care to prevent death or permanent disability. Unfortunately, the current stateof stroke diagnosis is limited to fixed neuroimaging facilities that do not allow rapid stroke diagnosis. Hence, a portable stroke-diagnosis device could assist in the pre-hospital triage of patients. Moreover, such a portable device could also be useful for bedside stroke monitoring of patients in the Neuro Intensive Care Unit (Neuro-ICU) to avoid unnecessary neuroimaging. Recent animal studies and numerical simulations have supported the idea of implementing Electrical Bioimpedance (EBI) in a portable device, allowing non-invasive assessment as a useful tool for the pre-hospital triage of stroke and Traumatic Brain Injury (TBI) patients. Unfortunately, these studies have not reported any results from human subjects in the acute phase of the stroke. The numerical simulations are also based on simple models that sometimes lack necessary ...
The main factors causing stroke are some of the causes that can bring this stroke disease appears. Stroke is a type of disease that attacks the nervous system of the body, resulting in paralysis, if not addressed or handled quickly. Symptoms of this stroke can also experience a hiccup. Then, there are also ways to prevent this stroke, and how to prevent it easily is to do regular exercise. This stroke, experienced by anyone either male or female. But this disease mostly occurs in old age. The age of twilight is easily attacked by various kinds or types of diseases. And one of them is a stroke. Then there is also the main factor causing this stroke. The main factor causing stroke is the age factor. Usually, people, who have an age that is old or advanced, can be susceptible to various diseases. And one of the diseases is a stroke. This type of cause can cause this stroke. Therefore, you should be able to maintain a healthy condition of the body or body properly and correctly, so as not easy to ...
burtontabaac. Warach SJ, Dula AN, Milling Jr TJ. Tenecteplase Thrombolysis for Acute Ischemic Stroke. Stroke. 2020;51:3440-3451.. This topical review takes a deep dive analysis into the literature as it pertains to Tenecteplase (tNK), a type of IV thrombolysis, in the treatment of acute ischemic stroke. A qualitative synthesis of published stroke trials is presented. Most interestingly is the argument, using meta-analysis, that tNK is superior in recanalizing large vessel occlusions (LVO) compared to Alteplase (tPA). This resonates with the vascular neurology world because the original prospective studies were unable to demonstrate superiority or non-inferiority of tNK on clinical outcome. As detailed, the current body of clinical trial evidence evaluating tNK relative to tPA points in the direction of superior early recanalization in LVO and non-inferior disability-free outcome at 3 months in favor of tNK.. In regards to dosing, current clinical practice guidelines for stroke include IV tNK ...
Mild hypoxia is common in stroke patients and may have significant adverse effects on the ischemic brain after stroke. The use of oxygen treatment is rapidly increasing in European stroke units but is not without side effects. It impedes early mobilization, could pose an infection risk, and may encourage the formation of toxic free radicals, leading to further damage to the ischemic brain. In the Stroke Oxygen Pilot Study (2 or 3 L/min for 72 hours) neurological recovery at one week was better in the oxygen group than in controls, and after correction for difference in baseline stroke severity and prognostic factors, there was a trend to better outcome with oxygen at six months. Oxygen was as effective in mild as in severe strokes. Oxygen saturation is lower at night than during the day, and episodes of oxygen desaturation are common during sleep. Nocturnal oxygen supplementation is likely to reduce the burden of hypoxia without interfering with daytime mobilization and rehabilitation. Before wider use
TY - JOUR. T1 - Revascularization grading in endovascular acute ischemic stroke therapy. AU - Zaidat, O. O.. AU - Lazzaro, M. A.. AU - Liebeskind, D. S.. AU - Janjua, N.. AU - Wechsler, L.. AU - Nogueira, R. G.. AU - Edgell, R. C.. AU - Kalia, J. S.. AU - Badruddin, A.. AU - English, J.. AU - Yavagal, Dileep R. AU - Kirmani, J. F.. AU - Alexandrov, A. V.. AU - Khatri, P.. PY - 2012/9/25. Y1 - 2012/9/25. N2 - Background: Recanalization and angiographic reperfusion are key elements to successful endovascular and interventional acute ischemic stroke (AIS) therapy. Intravenous recombinant tissue plasminogen activator (rt-PA), the only established revascularization therapy approved by the US Food & Drug Administration for AIS, may be less effective for large artery occlusion. Thus, there is enthusiasm for endovascular revascularization therapies, which likely provide higher recanalization rates, and trials are ongoing to determine clinical efficacy and compare various methods. It is anticipated that ...