TY - JOUR. T1 - Quality of life in patients with osteoporotic vertebral fractures. AU - Yoon, Sang Pil. AU - Lee, Seung Hwan. AU - Ki, Chul Hyun. AU - Lee, Young Tae. AU - Hong, Sung Ha. AU - Lee, Hwan Mo. AU - Moon, Seong Hwan. PY - 2014. Y1 - 2014. N2 - Study Design: A case-control study. Purpose: To examine several dimensions of health-related quality of life (HRQL) in postmenopausal women with osteoporotic vertebral fractures, compared with a control group. Overview of Literature: Osteoporotic vertebral fractures are a major cause of morbidity among postmenopausal women. There have been many reports of a decrease in the quality of life in patients with osteoporotic vertebral fractures. However,few reports have analyzed which dimensions contribute to the decline in quality of life. Methods: One thousand five hundred forty-five postmenopausal women aged 50 years and older from 17 study sites in nationwide hospitals were in enrolled in the study (between April 2008 and January 2009). HRQL was ...
Objectives To evaluate the efficacy of bone cement injection in PV for patients with acute painful osteoporotic compression fractures, as compared with a simulated placebo procedure without injection of bone cement. We hypothesize that patients who had undergone PV would report less pain at 1 day, 1 week and 1, 3, 6 and 12 months (the primary outcomes) than those in the sham control group.. Study design VERTOS IV is a multicenter RCT concerning the treatment of patients with a painful osteoporotic VCF. Patients are recruited on the Radiology departments of the participating hospitals and randomized to PV or a simulated procedure. Upon obtaining informed consent an independent central telephone operator completes the randomisation procedure, using a computer program. The maximum allowed unbalance (block size) is six, with a maximum sample size of 84 for each participating centre. A total of 180 patients will be enrolled, 90 in each group. This is based on the assumption of a 1.5 point difference ...
The objective of this study is to evaluate the efficacy of bone cement injection (PVP) for patients with acute painful osteoporotic compression fractures, as compared with a simulated procedure with injection of Lidocaine. Our hypothesis is, that patients who had undergone PVP would report less pain during the first 1-12 weeks and at 12 months (primary outcomes) than those in the sham control group.. The study design of VOPE is a single center double blinded RCT concerning the treatment of patients with a painful osteoporotic VCF. Patients are referred to the principal investigator at Middelfart hospital from the emergency rooms, orthopedics departments, GPs and chiropractors from the Region of Southern Denmark. Prior to enrolling patients randomization-envelopes are constructed in blocks of 20. Upon obtaining informed consent, a study-number is assigned to each patient. The final randomization for each patient, takes place in the operation room upon opening the sealed envelope deciding which ...
Vertebral fracture is usually the first osteoporotic fracture to occur and also the most common osteoporotic fracture, being present in 15% of women aged 50-59 years. Despite the clear clinical importance of vertebral fractures, they remain underdiagnosed in clinical practice. Good technique in performing spinal radiographs and a high level of observer experience in image interpretation are key to the reliable diagnosis of vertebral fractures. Vertebral fracture assessment (VFA) is being utilized increasingly for vertebral fracture identification. Density and structural parameters obtained by volumetric quantitative computed tomography (vQCT) can predict vertebral compressive strength ex vivo, and these parameters, together with nonlinear finite element analysis (FEA) can also be applicable in vivo. Magnetic resonance imaging (MRI) can detect minor acute or subacute vertebral fracture or re-fracture, determine fracture age, and distinguish between osteoporotic and neoplastic fracture with ...
Our purpose was to evaluate the diagnostic value of three-dimensional (3 D) CT surface reconstruction in spinal fractures in comparison with axial and reformatted images. A total of 50 patients with different CT-proven spinal fractures were analysed retrospectively. Based on axial scans and reformatted images, the spinal fractures were classified according to several classifications as Magerl for the thoraco-lumbar and lower cervical spine by one radiologist. Another radiologist performed 3 D CT surface reconstructions with the aim of characterizing the different types of spinal fractures. A third radiologist classified the 3 D CT surface reconstruction according to the Magerl classification. The results of the blinded reading process were compared. It was checked to see in which type and subgroup 3 D surface reconstructions were helpful. Readers one and two obtained the same results in the classification. The 3 D surface reconstruction did not yield any additional diagnostic information concerning type
Vertebral fracture risk is a heritable complex trait. The aim of this study was to identify genetic susceptibility factors for osteoporotic vertebral fracture applying a genome-wide association study (GWAS) approach. The GWAS discovery was based on the Rotterdam Study, a population-based study of elderly Dutch individuals aged ,55 years; and comprising 329 cases and 2666 controls with radiographic scoring (McCloskey-Kanis) and genetic data. Replication of one top-associated SNP was pursued by de-novo genotyping of 15 independent studies across Europe, the United States, and Australia and one Asian study. Radiographic vertebral fracture assessment was performed using McCloskey-Kanis or Genant semi-quantitative definitions. SNPs were analyzed in relation to vertebral fracture using logistic regression models corrected for age and sex. Fixed effects inverse variance and Han-Eskin alternative random effects meta-analyses were applied. Genome-wide significance was set at p,5 x 10(-8). In the ...
This page includes the following topics and synonyms: Cervical Spine Fracture, C-Spine Fracture, Clay Shovelers Fracture, Odontoid Process Fracture, Hangmans fracture, Jefferson Fracture, Cervical Wedge Compression Fracture, C1 Fracture, C2 Fracture, Cervical Teardrop Fracture, Cervical Spinous Process Fracture, Cervical Burst Fracture, Cervical Facet Dislocation, Cervical Fracture.
Vertebral fractures are common among postmenopausal women with glucocorticoid-induced bone loss. Midline (end-plate), anterior wedge, and crush fractures are the most common morphometric types of vertebral fractures. We found that BMD of the lumbar spine as measured by QCT was a significant predictor of prevalent vertebral fractures, whereas the posteroanterior DXA was unable to discriminate between the fracture and nonfracture groups. While some studies have shown that the underlying rheumatic disease itself can significantly increase the risk of vertebral fractures independently of glucocorticoid use (14), the distribution of these diseases was similar in both the fracture and nonfracture groups.. Lumbar spine posteroanterior DXA is commonly used to measure bone mass, diagnose osteoporosis, and predict the risk of vertebral fractures (5, 6). While some studies have demonstrated a significant correlation between lumbar spine DXA and prevalent vertebral compression fractures in postmenopausal ...
Vertebral fractures may be minor or lead to pain, decreased physical function, immobility, social isolation and depression, which together contribute to quality of life. A Working Party of the European Foundation for Osteoporosis has developed a specific questionnaire for patients with vertebral fractures. This questionnaire, QUALEFFO, includes questions in the domains pain, physical function, social function, general health perception and mental function. QUALEFFO was validated in a multicenter study in seven countries. The study was done in 159 patients aged 55-80 years with clinical osteoporosis, i.e., back pain and other complaints with at least one vertebral fracture and lumbar bone mineral density T-score |-1. Patients with a recent vertebral fracture were excluded because of unstable disease. Controls were age- and sex-matched, and did not have chronic back pain or vertebral fractures. Subjects with conditions exerting a major influence on quality of life were excluded. The QUALEFFO was
Denosumab reduces bone resorption and vertebral and nonvertebral fracture risk. Denosumab discontinuation increases bone turnover markers 3 months after a scheduled dose is omitted, reaching above-baseline levels by 6 months, and decreases bone mineral density (BMD) to baseline levels by 12 months. We analyzed the risk of new or worsening vertebral fractures, especially multiple vertebral fractures, in participants who discontinued denosumab during the FREEDOM study or its Extension. Participants received ≥2 doses of denosumab or placebo Q6M, discontinued treatment, and stayed in the study ≥7 months after the last dose. Of 1001 participants who discontinued denosumab during FREEDOM or Extension, the vertebral fracture rate increased from 1.2 per 100 participant-years during the on-treatment period to 7.1, similar to participants who received and then discontinued placebo (n = 470; 8.5 per 100 participant-years). Among participants with ≥1 off-treatment vertebral fracture, the proportion ...
Study Design. Cross-sectional observational study of incident spinal fractures using an administrative database. Objectives. To identify and define all patients who have spinal fractures within a complete population. Summary of Background Data. The true incidence of spinal column and cord injury is not known. Previous studies have been...
Vertebral fractures are the classic hallmark of osteoporosis, yet little is known of their epidemiology. The incidence of clinically diagnosed vertebral fractures was therefore directly assessed in the predominantly white (European descent) population of Rochester, Minnesota. Altogether, 341 Rochester residents were radiologically diagnosed for the first time with one or more vertebral fractures in the 5 year study period, 1985-1989. The overall age- and sex-adjusted incidence rate was 117 per 100,000 person-years (95% CI, 105 to 130). The age-adjusted rate in women (145 per 100,000 person-years) was almost twice that in men (73 per 100,000 person-years). Of all fractures, 47 (14%) followed severe trauma, 282 (83%) followed moderate or no trauma, and 12 (3%) were pathologic. Incidence rates for fractures following moderate trauma were higher in women than in men and rose steeply with age in both genders. In contrast, fractures following severe trauma were more frequent in men, and their incidence
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A study by Leslie WD of over 16,000 Canadian women, found that total hip BMD alone maximized overall osteoporotic fracture risk prediction. When there was a discrepancy between total hip and femoral neck, the total hip was more related to fracture risk. The spine measurement did not improve the fracture prediction. However, in this large study, only the clinical (symptomatic) spine fractures were included and the patients did not get routine xrays to see if they had actually developed a compression fracture of the spine. A subsequent study found that spine bone density predicted clinical vertebral fractures (hazard ratio 1.84 per standard deviation) and hip bone density predicted non-vertebral fractures (HR 1.66 per standard deviation). Using both measurements modestly improved overall fracture prediction if the discrepancy was more than one standard deviation. They then derived a modification of the FRAX prediction tool, which is described on the risk calculator page. This image shows the ...
TY - JOUR. T1 - Neurological L5 burst fracture. T2 - Posterior decompression and lordotic fixation as treatment of choice. AU - Ramieri, Alessandro. AU - Domenicucci, Maurizio. AU - Cellocco, Paolo. AU - Raco, Antonino. AU - Costanzo, Giuseppe. PY - 2012/5. Y1 - 2012/5. N2 - Purpose: We report our experience and literature review concerning surgical treatment of neurological burst fractures of the fifth lumbar vertebra. Materials and methods: Nineteen patients with L5 neurological burst fractures were consecutively enrolled; 6 patients had complete motor deficits, and 12 had sphincter dysfunction. We performed 18 posterior and one combined approaches. To avoid kyphosis, posterior internal fixation was achieved by positioning patients on the operating table with hips and knees fully extended. At the latest follow-up (mean 22 months, range 10-66), neurological recovery, canal remodeling and L4-S1 angle were evaluated. Results: Vertebral body replacement was difficult, which therefore resulted in ...
Fixed spinal fracture. Coloured frontal (left) and profile (right) X-rays of a section through the lower (lumbar) spine of a 30-old female patient after surgery to reduce (fix) a severe fracture of the L1 lumbar vertebra (highlighted, upper centre). Here, the fracture was fixed using a bone graft. - Stock Image C025/2513
TY - JOUR. T1 - Association of Incident, Clinically Undiagnosed Radiographic Vertebral Fractures With Follow-Up Back Pain Symptoms in Older Men. T2 - The Osteoporotic Fractures in Men (MrOS) Study. AU - Fink, Howard A.. AU - Litwack-Harrison, Stephanie. AU - Ensrud, Kristine E.. AU - Shen, Jian. AU - Schousboe, John T.. AU - Cawthon, Peggy M.. AU - Cauley, Jane A.. AU - Lane, Nancy E.. AU - Taylor, Brent C.. AU - Barrett-Connor, Elizabeth. AU - Kado, Deborah M.. AU - Cummings, Steven R.. AU - Marshall, Lynn. PY - 2017. Y1 - 2017. N2 - Prior data in women suggest that incident clinically undiagnosed radiographic vertebral fractures (VFs) often are symptomatic, but misclassification of incident clinical VF may have biased these estimates. There are no comparable data in men. To evaluate the association of incident clinically undiagnosed radiographic VF with back pain symptoms and associated activity limitations, we used data from the Osteoporotic Fractures in Men (MrOS) Study, a prospective cohort ...
Burst Fracture A burst fracture is a traumatic fracture of the bones of the spine often caused by a fall when you land on your feet. The fractured bones spread out and may damage the spinal cord. This video discusses the potential serious effects of this injury, which can lead to paralysis and other health problems.   
Information on spinal fractures, the causes, symptoms, risk factors and diagnosis. Medtronic provides helpful information for those suffering with back pain.
Focus Physiotherapy provides treatment for spinal fracture which is usually the result of a car accident, sports accident, fall or gunshot wound.
With all the recent confusion as to who will face Jon Jones for his Light Heavyweight title, several fighters have been left with different opponents in the wake of one of the most baffling stories in recent memory.. One person left out in the cold during all this is middleweight fighter, Alan Belcher, who went from having a fight scheduled with Vitor Belfort at UFC 153 on September 22nd, to having no opponent as Belfort was given a title shot against Jon Jones.. As Belcher stated earlier today on Twitter, however, this shift is a blessing in disguise as Belcher has sustained a serious injury, a spinal fracture. Now Belcher doesnt have to be the one to cancel on his opponent but instead fly under the radar and have a (hopefully) peaceful recovery before returning to his title run in the middleweight division.. Here is Belchers Tweet from earlier today.. Via Twitter @alanbelcherufc:. Everyones asking if I am mad at @Ufc @jonnybones @vitorbelfort answer is no. this is a blessing in disguise. I ...
Our results agree with three recent meta-analyses that examined study level data from trials of supplementation with vitamin D, calcium, or the two combined.12 13 26 The trials included in these systematic reviews differed slightly. Two reviews focused on vitamin D and also found that vitamin D alone was ineffective in preventing any fracture or hip fractures and that the combination of calcium and vitamin D showed benefit.12 13 Boonen et al did not examine "any fractures"12; in the Cochrane review, calcium and vitamin D prevented any fractures only in people living in institutions.13 By contrast, the findings of our individual patient data review strongly favoured calcium and vitamin D for prevention of any fractures in all populations examined. The Cochrane review did not find that clinical vertebral fracture was prevented by vitamin D with or without calcium supplementation,13 as found here, although few trials provided these data. These two previous systematic reviews did not assess the ...
The authors investigated if plasma Sphingosine 1-Phosphate (S1P) levels were a predictor for osteoporotic vertebral fracture (VF) risk. They found that S1P leve
Help for Burst Fractures using Spinal Touch Treatment. The Haven Healing Centre. Find Comfort and Relief from the Pain of Burst Fractures using Spinal Touch Therapy.
Vertebral fractures are a serious consequence of osteoporosis. Such a break can lead to acute and chronic back pain, spinal deformity and hip
Symptoms. The problem is spine fractures usually surface as just another routine back pain, that flares up when you bend or lift something heavy off the ground. However, it transforms from an acute pain to a nagging, chronic pain after a couple of months by which time you are resigned to loss of strength and mobility, regular pain, etc.. Diagnosis. This is also one of the reasons spine fractures are extremely difficult to diagnose, with less than 25% of cases being accurately found out before it has become a serious issue. The diagnosis is usually carried out by Xrays, CT scans and MRI, physical exams and complete evaluation of medical history. Women over 50 who are prone to osteoporosis should be carefully examined and treated.. If you constantly suffer from back pain, then its time to take a look the revolutionary product known as "Updesk" . With a promise to alleviate your chronic pain and stop you from writhing in agony during work, Updesk has become a nationwide bestseller and is widely ...
Most people with osteoporosis are unlikely to experience a spinal fracture during exercise. Keeping your back straight and learning safe moving and lifting techniques minimises your risk of spinal fractures and may help to relieve pain. This applies equally to you whether you have a spinal fracture or not.. With our range of information on exercises to care for your back, you can learn and continue to move with confidence.. ...
Objective To investigate the prevalence of vertebral fractures and to identify risk factors associated with vertebral fractures in Chinese women with systemic lupus erythematosus (SLE). Methods One hundred fifty-two consecutive patients with SLE were recruited in this cross-sectional study. Bone mineral density (BMD) measurements of the hip and spine were performed using the same dual energy X-ray absorptiometry (DEXA). Lateral radiographs of the spine (T5-L4) were assessed for vertebral fractures using a method described by Genant. Inflammatory and biochemical markers included C-reactive protein, receptor activator of nuclear factor-κB ligand, serum ß-CrossLaps assay for C-terminal telopeptides of type 1 collagen, and osteoprotegerin (OPG). Results Asymptomatic vertebral fractures occurred in 20.4% of patients with SLE. Univariate analyses of variables associated with fractures were older age, higher body mass index (BMI), lower BMD spine, lower BMD hips, higher serum C3 and C4, longer ...
We studied 51 patients with 64 fractures of the thoracolumbar and lumbar spine undergoing the surgical treatment by percutaneous trans-pedicular fixation and stabilization with minimally invasive...
The authors believe that the standardized and systematic study of immobilization techniques, diagnostic modalities, medical and surgical treatment strategies, and ultimately outcomes and outcome measurement after cervical spinal trauma and cervical spinal fracture injuries, if performed using well-designed medical evidence-based comparative investigations with meaningful follow-up, has both merit and the remarkable potential to identify optimal strategies for assessment, characterization, and clinical management. However, they recognize that there is inherent difficulty in attempting to apply evidence-based medicine (EBM) to identify ideal treatment strategies for individual cervical fracture injuries. First, there is almost no medical evidence reported in the literature for the management of specific isolated cervical fracture subtypes; specific treatment strategies for specific fracture injuries have not been routinely studied in a rigorous, comparative way. One of the vulnerabilities of an ...
Incidence of vertebral fractures over 3 years in patients in the lowest (n = 881) and highest (n = 867) tertiles for both b-ALP and sCTX. SR strontium
All 25 women (mean age 75.0, SD 4.7) with hip fracture as inclusion fracture had no significant changes in HRQOL between two and seven years and did not differ from the reference group regarding HRQOL after seven years. The vertebral group had significantly lower values for bodily pain, vitality, role-emotional ...
Mouthpiece Express : Denis Wick Practice Mute, French Horn [DW5530] - include mutestuff.txt | NOTE Denis Wick practice mutes are perhaps the best teaching aid ever inve...
URCA,Denis AUGOT Ingénieur de Recherche ANSES Né le 03 mars 1967 [email protected] Tél : 03 26 91 34 82 Fonction au sein de léquipe: Collaborateur. Epidémiologiste. Axe de recherche
Abnormal Spine X-Ray & Edema & Vertebral Fractures Symptom Checker: Possible causes include Spinal Metastasis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Macdonald, J.H. and Evans, S.F. and Davies, H.L. and Wilson, S. and Davie, M.W.J. and Sharp, C.A. (2012) A matched-cohort study of body composition, physical function and quality of life in men with idiopathic vertebral fracture. Arthritis Care and Research, 64 ((1)). pp. 92-100. DOI: 10.1002/acr.20580 ...
Studies have found that a majority of spine fractures are caused by auto accidents, following by participation in sports as well as diseases such as osteoporosis and spine tumors.
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This information is not designed to replace a physicians independent judgment about the appropriateness or risks of a procedure for a given patient. Always consult your doctor about your medical conditions or back problem. SpineUniverse does not provide medical advice, diagnosis or treatment. Use of the SpineUniverse.com site is conditional upon your acceptance of our User Agreement ...
This information is not designed to replace a physicians independent judgment about the appropriateness or risks of a procedure for a given patient. Always consult your doctor about your medical conditions or back problem. SpineUniverse does not provide medical advice, diagnosis or treatment. Use of the SpineUniverse.com site is conditional upon your acceptance of our User Agreement ...
Alan Belcher woke up Friday morning and found out that his scheduled opponent, Vitor Belfort, was no longer on the docket.. Belfort accepted a match with UFC light heavyweight champion Jon Jones, leaving Belcher without an adversary.. It turns out that Belcher likely wasnt going to be making the Belfort fight anyway, as he informed his Twitter followers that he has an injury. ...
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MINNEAPOLIS -- In long-term follow-up of the Womens Health Initiative, dietary supplementation with calcium and vitamin D was associated with a decreased risk for vertebral fractures, though not for
Dooley, Denis - Biographical entry - Plarrs Lives of the Fellows Online, NAME is a biographical, bibliographical and archival database of SUBJECT with links to related articles and images. ADD MORE DESCRIPTION AS REQUIRED
SPEAKER: Dr Denis OMeally, Centre for Animal Health Innovation, University of Sunshine Coast DATE: Friday, 16th September 2016 LOCATION: Geelong Campus at Waurn Ponds, Room KA4.207 TIME: 1:30pm Seminar will also be video linked to the following campuses: Melbourne Campus at Burwood, Burwood Corporate Centre (BCC) and Warrnambool Campus, Room J2.22 External visitors - wish to join us and connect to our…
LES ULIS, France--(Korea Newswire) December 22, 2017 -- On December 20th, a decree from the President of France was published in Le Journal Officiel* appointing Denis DELVAL CEO of LFB S.A. T
View all contributions by Dr. Denis Amer Zabalawi from SAINT-BRIEUC, France in the field of interventional cardiology and cardiovascular disease on PCRonline.
This is a faculty bioksketch for Denis Hadjiliadis. You will find research and clinical expertise, recent publications, and contact information.
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Denis Cross Индивидуальный стиль игры,Грамотная подборка треков в record-box,а затем такая же грамотная подача на танцпол . С первых моментов проведения времени за...