We report, for the first time, the remarkable efficacy of uttroside B, a potent saponin from Solanum nigrum Linn, against liver cancer. The compound has been isolated and characterized from the leaves of Solanum nigrum Linn, a plant widely used in traditional medicine and is a rich resource of several anticancer molecules. Uttroside B, that comprises of β-D-glucopyranosyl unit at C-26 of the furostanol and β-lycotetraosyl unit at C-3, is ten times more cytotoxic to the liver cancer cell line, HepG2 (IC50: 0.5 μM) than sorafenib (IC50: 5.8 μM), the only FDA-approved drug for liver cancer. Moreover, it induces cytotoxicity in all liver cancer cell lines, irrespective of their HBV status, while being non-toxic to normal immortalized hepatocytes. It induces apoptosis in HepG2 cells by down-regulating mainly the activation of MAPK and mTOR pathways. The drastic reduction in HepG2-xenograft tumor size achieved by uttroside B in NOD-SCID mice and substantiation of its biological safety through both acute
MicroRNAs (miRNAs) play key roles in regulating zinc (Zn) toxicity tolerance in plants. Solanum nigrum is a typical Zn/Cd-accumulating plant that has a high Zn/Cd tolerance. Despite their importance, no miRNAs have been identified from S. nigrum thus far. In this study, small RNA sequencing was used to identify Zn-responsive miRNAs in S. nigrum roots. We identified 176 differentially expressed miRNAs in S. nigrum roots in response to Zn toxicity. We also found that all these differentially expressed Zn-miRNAs simultaneously respond to the exogenous NO donor sodium nitroprusside (SNP), indicating that NO is involved in Zn-mediated miRNA expression in S. nigrum. These differentially expressed miRNAs are involved in regulating the following processes in S. nigrum roots: phenylpropanoid catabolic and metabolic processes; lignin catabolic and metabolic processes; and programmed cell death in response to ROS. These results suggest that these miRNAs play key roles in the Zn toxicity tolerance of S. ...
SOLANUM NIGRUM Black Nightshade Used with success in ergotism, with tetanic spasms and stiffness of whole body, with mania. Marked action on head and eyes. Meningitis. Chronic intestinal toxæmia. Brain irritation during dentition. Restlessness of a violent and convulsive nature.
Background: Advanced glycation end products (AGEs) signal through the receptor for AGE (RAGE), which can lead to hepatic fibrosis in hyperglycemia and hyperlipidemia. We investigated the inhibitory effect of aqueous extracts from Solanum nigrum (AESN) on AGEs-induced RAGE signaling and activation of hepatic stellate cells (HSCs) and hyperglycemia induced by high-fat diet with ethanol. Methods: An animal model was used to evaluate the anti-hepatic fibrosis activity of AESN in rats fed a high-fat diet (HFD; 30%) with ethanol (10%). Male Wistar rats (4 weeks of age) were randomly divided into four groups (n = 6): (1) control (basal diet); (2) HFD (30%) + ethanol (10%) (HFD/ethanol); (3) HFD/ethanol + AESN (100 mg/kg, oral administration); and (4) HFD/ethanol + pioglitazone (10 mg/kg, oral administration) and treated with HFD for 6 months in the presence or absence of 10% ethanol in dietary water. Results: We found that AESN improved insulin resistance and hyperinsulinemia, and downregulated lipogenesis via
Homeopathic Solanum Nigrum indications, uses & symptoms from 12 materia medicas, linked and cross referenced. Available 4X-30X, 2C-30C, 200C
Solanum nigrum fruits have been conventionally used in beverages due to their nutritional substances such as minerals, vitamins, amino acids, proteins, sugars, polyphenols, and anthocyanins. The characterization of components and regulatory mechanism of anthocyanins in S. nigrum fruits have rarely been reported. In this study, we determined that the peel and flesh of S. nigrum fruits shared similar HPLC profiles but different contents and total antioxidant activities for anthocyanins. After an efficient purification method, mainly including extraction with pH 1.0 distilled water and then desorption with pH 1.0 95% ethanol after a DM-130 resin adsorption step to obtain more pure anthocyanin extracts, the purity of anthocyanins extracted from S. nigrum fruits reached 56.1%. Moreover, eight anthocyanins from S. nigrum fruit were identified with HPLC-MS/MS for the first time. A typical R2R3-MYB transcription factor gene, SnMYB, was also cloned for the first time by rapid amplification of cDNA ends (RACE)
1. Name of Plants. Local name : Leunca (Sunda), Ranti (Jawa), anti, Bobosa (Maluku). Foreign name : long kui (Tiong Hoa), enab el-deeb (Arab). Latin name : Solanum nigrumL.. Synonym : S. fistolosum Rich, S. nodiflorum Jacq. Solanum guineense (L) Lam. (Iwu, 1993; Wijayakusuma, 2005).. 2. Classification of Plants. Kingdom : Plantae (Tumbuhan). Subkingdom : Tracheobionta (Tumbuhan berpembuluh). Super Division : Spermatophyta (Menghasilkan biji). Division : Magnoliophyta (Tumbuhan berbunga). Class : Magnoliopsida (berkeping dua/dikotil). Sub Class : Asteridae. Order : Solanales (suku terung-terungan). Family : Solanaceae. Genus : Solanum. Species : Solanum nigrumL. (Kartesz, 2004). 3. Description of Plants. This plant belongs to the class of the bush, with a height of approximately 1.5 m. Has a taproot with a brownish-white color. Stem upright, round, soft, and green. Single leaf, oval, and scattered with 5-7.5 cm long ; 2.5-3.5 cm wide. Tapered leaf base and tip with flat edge. Bone pinnate leaves. ...
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
8. TOXICOLOGICAL/TOXINOLOGICAL ANALYSES AND BIOMEDICAL INVESTIGATIONS 8.1 Material sampling plan 8.1.1 Sampling and specimen collection 8.1.1.1 Toxicological analyses 8.1.1.2 Biomedical analyses 8.1.1.3 Arterial blood gas analysis 8.1.1.4 Haematological analyses 8.1.1.5 Other (unspecified) analyses 8.1.2 Storage of laboratory samples and specimens 8.1.2.1 Toxicological analyses 8.1.2.2 Biomedical analyses 8.1.2.3 Arterial blood gas analysis 8.1.2.4 Haematological analyses 8.1.2.5 Other (unspecified) analyses 8.1.3 Transport of laboratory samples and specimens 8.1.3.1 Toxicological analyses 8.1.3.2 Biomedical analyses 8.1.3.3 Arterial blood gas analysis 8.1.3.4 Haematological analyses 8.1.3.5 Other (unspecified) analyses 8.2 Toxicological Analyses and Their Interpretation 8.2.1 Tests on toxic ingredient(s) of material 8.2.1.1 Simple Qualitative Test(s) 8.2.1.2 Advanced Qualitative Confirmation Test(s) 8.2.1.3 Simple Quantitative Method(s) 8.2.1.4 Advanced Quantitative Method(s) 8.2.2 Tests for ...
Le nom générique, « Solanum », est un terme latin attesté dabord chez Celse (De Medicina [II, 33][6]) puis chez Pline lAncien (Historia naturalis [21, 177 et 27, 132]), équivalent du terme grec στρύχνος (strychnos), attesté chez Théophraste et Dioscoride, qui désignait la morelle noire (Solanum nigrum) [7]. Strychnos a été repris par Linné pour désigner un autre genre botanique sans parenté avec les Solanaceae. Solanum pourrait dériver du latin sol, « soleil », sans quon en connaisse la raison car les espèces ne sont pas connues pour être héliophiles. Une autre hypothèse est quil vienne du latin solare, « soulager », en référence aux propriétés émollientes et adoucissantes des racines[8]. Le nom vernaculaire de morelle vient du latin médiéval maurella, littéralement « petit maure », en référence à la baie noire comme un Maure de Solanum nigrum[9]. ...
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Plant standardization requires determination of the total content of various classes of secondary metabolites, due to dosage determination in the preparation. Black nightshade (Solanum nigrum L.) is one of the ethomedicines in Indonesian society. The purpose of this study was to determine the total alkaloids and flavonoids content in leaf, fruit, a
In summer 2012, carrot (Daucus carota L.) plants displaying symptoms of leaf yellowing, stunting and proliferation of dwarfed shoots with bushy tops, and a dense hairy growth of secondary roots were observed. Symptomatic carrots were collected from three fields used for seed production and located in Region Centre of France near Orléans. The presence of psyllids (Psyllidae) in one of the fields was reported but they were not clearly identified. Fifty percent of the field was infected. Due to a large amount of plant debris, the harvested seeds were difficult to separate and the germination rate was low (from 10 to 77%), rendering them unmarketable. The symptoms observed were similar to those described for carrots infected by Aster yellows phytoplasma and Candidatus Liberibacter solanacearum in Europe (3). Total DNA was extracted from petiole and root tissue of 16 symptomatic and 6 asymptomatic carrots (cv. Amsterdam, CAC3075), 2 samples of black nightshade leaves (Solanum nigrum) collected ...
Scope and Contents: Location: Nahant. Notes: Mounted. Noted as a "memo". Note by Blackford on the back of the plate stating, "Solanum nigrum L. Although the fruit of this plant is reputed poisnonous, nevertheless in some places it is used in making pies. The plant is even cultivated for its fruit. A form bearing very large fine fruit was observed in a garden at Rossie and the proprietor assured me he used the fruit for food. Cooking appears to destroy its deleterious qualities. The cultivated form is locally known as garden huckleberry. State Bot. N.Y.C.H. Peck." (Quoted from the Museum Bulletin, Issues 137-140 by the New York State Museum, 1910 ...
A 36-year-old man with underlying chronic lymphocytic leukemia had left arm swelling for a duration of 3 months. Clinically, the affected arm was swollen, erythematous and tender. Epicoccum nigrum was isolated from the culture of the tissue that was obtained intra-operatively. He was treated and responded to voriconazole therapy. To the best of our knowledge, this is the first case of intramuscular abscess as a result of E. nigrum infection in an immunocompromised patient.. ...
A common anti-seizure drug may be effective against certain conditions associated with lupus, according to animal research at Wake Forest University School of Medicine.
Roślinna farba do włosów w proszku BRONZE (brąz) | do włosów w odcieniu średni blond po średni brąz | Włosy \ Roślinne farby do włosów \ W proszku (do samodzielnego przygotowania) Producenci \ SANTE Naturkosmetik LESS WASTE \ Less waste | kosmetyki naturalne, ekologiczne środki czystości oraz suplementy diety
Nerve pain can be a symptom of many different conditions, includingcancer, HIV, diabetes, and shingles. For some, nerve pain is frustrating; for others, nerve pain is devastating and life-changing.. Whether it feels like burning, pinpricks, or sudden shocks of electricity, nerve pain can disrupt your life at home and at work. It can limit your ability to get around. Over time, it can grind you down. Studies show that people with nerve pain have higher rates of sleep problems,anxiety, and depression.Your nervous system is involved in everything your body does, from regulating your breathing to controlling your muscles and sensing heat and cold.. There are three types of nerves in the body:. ...
Brrrrr! Nogen må godt snart tænde for varmen, derude! Men indtil da, kan vi heldigvis spise os varme. Jeg er vild med suppe. Især hvis det er af den slags, man også bliver mæt af. Det gør du af denne thaisuppe med kylling. Både fordi der er masser af protein, fedt og grønt - men…
Proceder fałszowania produktów spożywczych spotykany jest od wieków. Dokonuje się tego na wiele, mniej lub bardziej skomplikowanych, sposobów. Fałszowane są wszelkie możliwe grupy żywności, na każdym etapie produkcji i dystrybucji [32]. Jednym z najczęściej fałszowanych produktów spożywczych są oleje roślinne. Wśród metod wykrywania zafałszowań olejów wyróżnia się metody fizykochemiczne, chromatograficzne, izotopowe, spektralne, elektroforetyczne, immunologiczne i biologii molekularnej, biologiczne i metody wykorzystujace elektroniczny nos.
Przewodnik do ćwiczeń z biochemiczno-biofizycznych podstaw rozwoju roślin (wersja dwujęzyczna) przygotowany został z myślą o studentach biotechnologii Międzyuczelnianego Wydziału Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego, może być jednak przydatny również dla studentów innych kierunków studiów przyrodniczych. Omówiono w nim doświadczenia eksperymentalne demonstrujące różne procesy związane z rozwojem roślin. Doświadczenia te obejmują wybrane zagadnienia z biochemii, fizjologii i cytologii roślin. Opis każdego doświadczenia poprzedzony został zwięzłym wstępem teoretycznym.. Spis treści / ...
Mne spis fascinuje, ze jeho belossti volici jsou ochotni pastora Wrighta spolknout a navrch jeste Obamovu manzelku. Skoro to vypada, ze blue collars Clintonove jsou jedini demokraticti volici, kteri maji zdravy rozum. A stran toho, kam Obama patri, no, podle citovanych odstavcu z te jeho knihy je jasne, ze by rad byl stoprocentnim cernochem, ale v hloubi duse vi, ze to neni pravda. Tu jeho cernou identifikaci nechapu, protoze jeho kensky taticek se na rodinu vykaslal, kdyz Obamovi byly 2 roky a za celou vychovu a vzdelani vdeci bile casti sveho rodokmenu.. ...
PAPER Meszlényi V, Patai R, Polgár TF, Nógrádi B, Körmöczy L, Kristóf R, Spisák K, Tripolszki K, Széll M, Obál I, Engelhardt JI, Siklós L ...
I følge "nationalnyckeln" er dødningehoved larve i det sydlig Danmark og Sverige fundet på: Kartoffel, Solanum tuberosum. Bukketorn, Lycium barbarum. Virginiatobak, Nicotiana tabacum. Liguster, Ligustrum vulgare. Sommerfuglebusk, Budddleja davidii. Sort Natskygge, Solanum nigrum & Almindelig Pigæble, Datura stramonium. Efterhånden som larverne bliver større op til 13 cm stor, foretrækker de marknære gule blade ...
The effects of Liv.52 are not immediate. Although you may experience the benefits of Liv.52 2 to 4 weeks after beginning treatment, treatment for up to 12 weeks may be necessary before Liv.52 takes effect.. DOSAGE. Please consult your physician to prescribe the dosage that best suits your condition.. If you miss a dose of this medicine and you are using it regularly, take it as soon as possible. If you do not remember until later, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.. STORAGE. Store at the room temperature away from moisture and sunlight. Keep out of reach of children.. MORE INFO:. Active ingredient: Himsra (Capparis spinosa), Kasani (Cichorium intybus). Other components:. Kakamachi (Solanum nigrum) ...
The effects of Liv.52 are not immediate. Although you may experience the benefits of Liv.52 2 to 4 weeks after beginning treatment, treatment for up to 12 weeks may be necessary before Liv.52 takes effect.. DOSAGE. Please consult your physician to prescribe the dosage that best suits your condition.. If you miss a dose of this medicine and you are using it regularly, take it as soon as possible. If you do not remember until later, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.. STORAGE. Store at the room temperature away from moisture and sunlight. Keep out of reach of children.. MORE INFO:. Active ingredient: Himsra (Capparis spinosa), Kasani (Cichorium intybus). Other components:. Kakamachi (Solanum nigrum) ...
Piper Nigrum drug should be used to end the symptoms as grief, sensation of loss of body power, restlessness in mind and startling to a slight noise. a good cheap medical health care plan.
Deadly nightshade leaf. Coloured scanning electron micrograph (SEM) of a section through a deadly nightshade (Atropa belladonna) leaf. Four chloroplasts (green) are seen across centre. Chloroplasts are the sites of photosynthesis, the process that synthesises carbohydrates from carbon dioxide and water using sunlight. The pigment responsible for photosynthesis, chlorophyll, is found on stacks of parallel thylakoids (green lines) called grana. Starch grains (grey) are seen within the chloroplasts. Magnification: x10,000 when printed at 10 centimetres wide. - Stock Image C020/8525
JOHNNY DARTER. SCIENTIFIC NAME: Ethostoma nigrum. CHARACTERISTICS: Etheostoma nigrum males typically darken during the breeding season or acquire dark stippling that develops into dark bands along the sides. Females have slight yellowish cast. A frenum is absent on the upper lip and a black bridle extending across the somewhat blunt snout is interrupted above the upper lip, a feature which usually separates E. nigrum from the similar bluntnose darter, E. chlorosonum. Six to seven saddles are present on the back; and seven to 10 blotches are variously developed into W-, V-, or X-shaped markings along the side. A distinct spot is present at the base of the caudal fin and at the front of the spiny dorsal fin. Small spots occur on the spines and rays of both dorsal fins, presenting somewhat of a banding pattern. Krotzer (1990) examines variation and systematics of E. nigrum throughout its range.. ADULT SIZE: 1 to 2.8 in (25 to 70 mm). DISTRIBUTION: Etheostoma nigrum occurs widely throughout the ...
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Learn about cannabis as an anti-seizure medication for seizure treatments. Seizures occur when the brains nerve cells fire random electrical pulses.
The anti-seizure drug, Onfi, has been linked to severe skin reactions such as Stevens-Johnson Syndrome (SJS) and Toxic Epidural Necrolysis (TEN).
SAN DIEGO, CA--(Marketwired - May 10, 2017) - Aegis Therapeutics LLC announced today that it has been awarded U.S. Patent No. 9,642,913, the fourth patent providing non-invasive metered nasal spray delivery of anti-seizure drugs to the CNS. The enabling Aegis Intravail formulation technology is broadly applicable to a wide range...
Raport Roczny 2004 Annual Report 2004 Spis treści Contents List Prezesa 2 From the President Rynek hotelowo-turystyczny w Polsce 24 Hotel and Tourist Market in Poland Zarząd i Rada Nadzorcza 4 Management
If Your Looking For A New Bong Or Vaporiser, Then Look No Further Shiva Online Stock Leading Brands Such As Roor, Chongz, Abaxian & Cheeky One ...
Curaderm BEC 5 consists of active anticancer ingredient Solasodine Glycosides. Therefore it s commonly known as BEC5. It also contains Saliyclic Acid and Urea at a very high concentration. This assists the BEC 5 to kill cancer cells. (Note: Saliyclic Acid and Urea may irate the skin ...
Results: HQG treatment inhibited hepatoma growth in tumour-bearing mice. Cell apoptosis rate of human hepatoma 7402 cells and of the cells from ascites in tumour-bearing mice was increased after HQG treatment. Mitochondrial membrane potential in human hepatoma 7402 cells was decreased after HQG treatment. CD4+ and CD8+ T- lymphocytes subpopulation was increased while the ratio of CD4+/ CD8+ decreased in tumour-bearing mice after HQG administration. IFN-γ and IL-4 secretion was increased in spleen lymphocytes in tumour-bearing mice after HQG administration ...
Surgery was now confirmed for 01.24.2005. The procedure should take about four hours total. After that, I would likely be in the hospital for three to four days. Once I am able to walk around, use the restroom, eat, etc. on my own I would be able to leave the hospital. I would probably be wiped out for a couple weeks and be a couch potato. I would likely be able to resume driving after a reasonable period after the surgery as long as I took the anti-seizure medication. I would need to have follow-up MRI scans at regular intervals after the procedure to monitor the tumor ...
An existing anti-seizure drug improves memory and brain function in adults with a form of cognitive impairment that often leads to full-blown Alzheimer s disease, a Johns Hopkins University study has...
Tachycardia, stroke NR 11 NR NRInduces fat reduction, stimulant Ameliorates menopausal symptoms1 2NR Anti-seizure effects (animals) NRAssociated with seizures
Tibia.pl - jedna z największych na świecie stron o grze Tibia. Tony informacji, spis questów, potworów, przedmiotów, broni. Poradniki oraz ogromne forum!
Stored Product Insects (SPIs) in Food Environments and Flies and their control join the line up of BPCA online classroom courses for pest professionals.
Tibia.pl - jedna z największych na świecie stron o grze Tibia. Tony informacji, spis questów, potworów, przedmiotów, broni. Poradniki oraz ogromne forum!
China Health-Care Food Ribes Nigrum Black Current Seed Oil, Find details about China Black Current Seed Oil, Grape Seed Oil from Health-Care Food Ribes Nigrum Black Current Seed Oil - Hebei Xinqidian Biotechnology Co., Ltd.
Latin Name: Other Names: pepper, peppercorns Medicinal Uses: Digestive system tonic, Rheumatism, Nausea, Flatulence, Laxative Black Pepper: (spice) Dried, mature berries of a tropical vine. The whole dried berry (peppercorn) is used for black pepper. Black pepper (Piper nigrum) is a flowering vine in the family Piperaceae, cultivated for its fruit, which is usually dried…
Fruit extracts from black currants (Ribes nigrum L.) are traditionally used for treatment of gastritis based on seed polysaccharides that inhibit the adhesion of Helicobacter pylori to stomach cells. For detailed investigations an arabinogalactan protein (F2) was isolated from seeds and characterized concerning molecular weight, carbohydrate, amino acid composition, linkage, configuration and reaction with beta-glucosyl Yariv. Functional testing of F2 was performed by semiquantitative in situ adhesion assay on sections of human gastric mucosa and by quantitative in vitro adhesion assay with FITC-labled H. pylori strain J99 and human stomach AGS cells. Bacterial adhesins affected were identified by overlay assay with immobilized ligands. I-125-radiolabeled F2 served for binding studies to H. pylori and interaction experiments with BabA and SabA. F2 had no cytotoxic effects against H. pylori and AGS cells; but inhibited bacterial binding to human gastric cells. F2 inhibited the binding of BabA and ...
PubMed journal article: The antioxidant and radical scavenging activities of black pepper (Piper nigrum) seeds. Download Prime PubMed App to iPhone, iPad, or Android
Galba truncatula can occupy both temporary and permanent freshwater habitats.[15][16] The species occurs commonly in shallow well aerated water, in marshes, ponds, lakes, streams, rivers, water ditches.[15][17] In France, the populations of Galba truncatula are declining because its habitat is threatened by modern agricultural practices.[18] In case of larger water bodies, the snail occurs mostly on the edge between water and land, sometimes outside water layer on mud.[15] Galba truncatula can be very abundant, with high population densities and it has an evident anthropophily including usual presence in human neighbourhood.[4] Galba truncatula is amphibious organism and can survive long dry periods. This is caused by its high ability to aestivate during drought conditions. It is known that Galba truncatula can survive 6 weeks to 4.5 months of dry periods in aestivated stage in mud. In the laboratory cultures, Kendall (1949) observed survival over 1 year in Petri dishes without water.[15] The ...
Meanwhile while all my plants are growing happily, there are these -my Survival plants, the Brahma kamal plants look happy and grow and then start to become quiet!Added new plants, and they are looking great on window sill, I am calling them survival plants as they are not taking too well to our open space under the sun, neither are they shooting up into leaves fast. Just about after a month or so some new progress is seen. My obsession with the plant continues, and while all are saying leave this, they will not grow, my soul still longs to experience this beautiful magical happiness of seeing them bloom, Still hoping one day , maybe I will see the Brahma kamal plants give out buds.. bloom ...