Also known as: Obstructive Sleep Apnea (OSAS) / Apnea, Obstructive Sleep / Obstructive Sleep Apnea / Obstructive Sleep Apnea (OSA) / Obstrutive Sleep Apnea / Sleep Obstructive Apnea / Sleep Apnea - Obstructive / Sleep Apnea, Obstructives / Sleep Apnea Obstructive (OSA) / OSA - Obstructive Sleep Apnea / Obstructive Sleep Apnea (SAOS) / Sleep Apnea Syndrome (OSAS) / OSA / OSAS / OSAS (Obstructive Sleep Apneas Syndrome) / Obstructive Sleep Apnea Syndromes / Obstructive Sleep Apnea Syndrome and / Sleep Apnea Syndromes, Obstructive / Obstructive Sleep-Apnea Syndrome / Obstructive Sleep Apnoea Syndrome / Syndrome, Obstructive Sleep Apnea / Obstructive Sleep Apnea Syndrome (OSAS) / Obstructive Sleep Apnea Syndrome / Obstructive sleep apnea hypopnea / Sleep apnea syndrome / Sleep Apnea Syndromes / Sleep apnoea syndromes / Sleep apnea / Sleep apnoea syndrome / Apnea syndrome / Apnoea syndrome / Sleep apnoeas / Sleep apnoea ...
Obstructive sleep apnea is a subtype of sleep disordered breathing. In obstructive sleep apnea, there is a physical obstruction to airflow despite an adequate respiratory drive. The most common symptomatic manifestation of obstructive sleep apnea is snoring. This sleep disorder is characterized by apneas which are abnormally long pauses in breathing during sleep. In addition, abnormally low breathing rates occur and they are termed hypopneas. Obstructive sleep apnea has been associated with the development of several medical diseases including hypertension, coronary artery disease, congestive heart failure, and diabetes. We have recently discussed the finding that sleep disordered breathing is associated with increased risk of developing mild cognitive impairment and dementia. Cardiac arrhythmias have also been shown to be associated with severe obstructive sleep apnea. Researchers led by Dr. Silje K. Namtvedt have shown that even mild obstructive sleep apnea in middle aged individuals is ...
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Title. Obstructive sleep apnoea syndrome - patients perceptions of their sleep and its effects on their life situation Aim. This paper reports a descriptive study of how untreated patients with obstructive sleep apnoea syndrome perceived their sleep situation and how the syndrome affected their life situation. Background. Obstructive sleep apnoea syndrome is a prevalent problem independently associated with an increased risk for hypertension, cardiovascular disease, chronic heart failure and mortality. Increased consumption of healthcare resources can often be seen among patients over a long period of time since many have been undiagnosed and untreated. Methods. A phenomenographic approach was employed. Data were collected by interviews during 2005 with 20 purposively selected participants with untreated obstructive sleep apnoea syndrome. Findings. Participants described loud snoring, frequent awakenings, dyspnoea, frustration over nocturia, fear of dying during sleep and partners anxiety ...
The purpose of this study is to estimate the cost-utility of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients in Sao Paulo city, Brazil, after 3 years of treatment and to estimate the cost-effectiveness of CPAP on the number of medical visits, hospitalizations, medical examinations, used medications, new case incidence and cost of traffic accidents and absence from work. It is also designed to estimate quality-adjusted extended years of life, and to assess cost-effects of the therapy (device, masks, supplies, maintenance/year for membership of professional consulting, electric power) on the cost- ...
The etiology and pathogenesis of sleep obstructive apnea hypopnea syndrome (OSAHS) is not yet definitive, evidence shows that the dysfunction of pharyngeal nerve and the atonia of the muscle innervated by these nerve could play an important role in the progress of OSAHS. Dopamine is a neurotransmitter in the central nervous system which significantly affects the sleep-awake regulation. So far mounting evidence shows that dopamine has a potential role in the modulation of hypoglossal nucleus. The progress of dopamine in obstructive sleep apnea hypopnea syndrome is reviewed in this article.
Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep Medicine, Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009 Jun 15;5(3):263-76.. Aurora RN, Casey KR, Kristo D, Auerbach S, Bista SR, Chowdhuri S, et al. Practice parameters for the surgical modifications of the upper airway for obstructive sleep apnea in adults. Sleep. 2010 Oct;33(10):1408-13.. Ballard RD. Management of patients with obstructive sleep apnea. J Fam Pract. 2008 Aug;57(8 Suppl):S24-30.. Barbé F, Durán-Cantolla J, Sánchez-de-la-Torre M, Martínez-Alonso M, Carmona C, Barceló A, et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA. 2012 May 23;307(20):2161-8.. Basner RC. Continuous positive airway pressure for ...
Metabolic syndrome and cardiovascular disease are strongly associated with obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal circadian physiological functions, including metabolic pathways. Because core clock genes are known to be modulated by sleep/vigilance cycles, we asked whether the expression level of mRNA coding for clock genes is altered in non-treated OSAS patients and if it can be corrected by standard continuous positive airway pressure (CPAP) treatment ...
Metabolic syndrome and cardiovascular disease are strongly associated with obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal circadian physiological functions, including metabolic pathways. Because core clock genes are known to be modulated by sleep/vigilance cycles, we asked whether the expression level of mRNA coding for clock genes is altered in non-treated OSAS patients and if it can be corrected by standard continuous positive airway pressure (CPAP) treatment ...
TY - JOUR. T1 - Impact of obstructive sleep apnea on blood pressure and cardiovascular risk factors in Japanese men. T2 - A cross-sectional study in work-site group. AU - Morinaga, Yuki. AU - Matsumura, Kiyoshi. AU - Kansui, Yasuo. AU - Sakata, Satoko. AU - Goto, Kenichi. AU - Haga, Yoshie. AU - Oishi, Emi. AU - Seki, Takunori. AU - Ohtsubo, Toshio. AU - Kitazono, Takanari. PY - 2018/1/2. Y1 - 2018/1/2. N2 - It has been shown that obstructive sleep apnea (OSA) is related to hypertension and cardiovascular disease; however, the prevalence of OSA in general population and the impact of it on blood pressure especially in Japan has not been well determined. We have conducted a screening test for OSA from 2003 to 2011. In addition, a cross-sectional analysis was performed in 2012 to determine the association of OSA and cardiovascular risk factors in Japanese men (18-69 years of age; mean age, 44.4 ± 0.2). The study group consisted of 2208 male employees, and OSA was evaluated by using the 4% oxygen ...
Respiration 1997; 64(2):159-61. ABSTRACT. We studied the effects of modafinil, a vigilance-enhancing drug, on excessive daytime sleepiness, memory, night sleep and respiration in 6 patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) using a double-blind random cross-over design with 24-hour polysomnography, verbal memory test and a 5-week sleep-wake diary kept by the patients. There were two 2-week treatment periods in which either modafinil or placebo was used; they were separated by a 1-week wash-out period. Our results show that modafinil reduces daytime sleep duration, lengthens the duration of subjective daytime vigilance and improves long-term memory in patients with OSAHS without modifying night sleep and respiration events.. ...
Continuous Positive Airway Pressure machiness simply termed as CPAP machines are used in treating obstructive sleep apnea. It prevents sleep apnea by supplying a steady and constant flow of air pressure through your airway. Sleep apnea can be termed as a condition marked by repeated and brief interruptions in an individuals breathing during sleep. Sleep apnea has many side effects such as drowsiness which reduces your productivity throughout the day. The main objective of a CPAP machine is to eliminate the struggle between sleep and breathing. This enables the machine to correct your breathing patterns throughout the night. Below are the pros of using a CPAP machine in eliminating obstructive sleep apnea.. 1. Minimizes the Risk of Cardiovascular Diseases. Heart disease which is popularly termed as the problem of lungs can be caused by untreated obstructive sleep apnea. Sleep apnea interferes with your breathing pattern which concurrently changes your blood pressure. This will, therefore, cause ...
The No-apnea score vs . the other five questionnaires in screening for obstructive sleep apnea-hypopnea syndrome in patients with cerebral infarction
Obstructive sleep apnea (OSA) is one of the most common sleep disturbances, and it has been estimated that one out of five adults has at least some degree of sleep related breathing disturbances. Obstructive sleep apnea affects mostly the middle-aged work force, and causes a negative impact on public health by increasing both morbidity and mortality. Obesity is related to many diseases including diabetes, cardiovascular diseases, and metabolic syndrome,and obesity is also considered as the most important risk factor for OSA.Considering the prevalence of mild OSA, and the beneficial effects of even a slight weight loss on both the severity of OSA and the likelihood of developing OSA, lifestyle intervention including weight reduction represents a viable option for the treatment of patients with mild OSA.However, although included in the clinical guidelines, there is a definite lack of well executed studies on the effect of weight reduction upon OSA. Accordingly, we are conducting a randomized ...
TY - JOUR. T1 - Missing teeth and pediatric obstructive sleep apnea. AU - Guilleminault, Christian. AU - Abad, Vivien C.. AU - Chiu, Hsiao Yean. AU - Peters, Brandon. AU - Quo, Stacey. PY - 2016. Y1 - 2016. N2 - Background: Missing teeth in early childhood can result in abnormal facial morphology with narrow upper airway. The potential association between dental agenesis or early dental extractions and the presence of obstructive sleep apnea (OSA) was investigated. Methods: We reviewed clinical data, results of polysomnographic sleep studies, and orthodontic imaging studies of children with dental agenesis (n = 32) or early extraction of permanent teeth (n = 11) seen during the past 5 years and compared their findings to those of age-, gender-, and body mass index-matched children with normal teeth development but tonsilloadenoid (T&A) hypertrophy and symptoms of OSA (n = 64). Results: The 31 children with dental agenesis and 11 children with early dental extractions had at least 2 permanent ...
Title: Obstructive Sleep Apnea Syndrome and Upper Airway Inflammation. VOLUME: 4 ISSUE: 1. Author(s):Hasan M. Inancli and Murat Enoz. Affiliation:Deniz Abdal Mah. Veled Celebi Sok. No: 42 Isyk Apt. A-Blok, Daire: 9, Postal Code: 34092, Findikzade, Istanbul, Turkey.. Keywords:Sleep apnea, inflammation, markers, cytokines, C-reactive protein. Abstract: Obstructive sleep apnea syndrome (OSAS) is associated with inflammatory processes and elevated plasma cytokines. Inflammatory processes associated with OSAS may also act as potential mediators of cardiovascular morbidity in these patients. OSAS is associated with elevated levels of C reactive protein (CRP), as a marker of inflammation and cardiovascular risk. At the inflammatory point of view, the levels of TNF-α, IL-6, hsCRP, adhesion molecules, monocyte chemoattractant protein-1 and resistin were markedly and significantly elevated in patients with sleep apnea than those in normal control subjects. We reviewed several recent patents and ...
Obstructive sleep apnea (OSA) is the most common type of sleep apnea and is caused by complete or partial obstructions of the upper airway. It is characterized by repetitive episodes of shallow or paused breathing during sleep, despite the effort to breathe, and is usually associated with a reduction in blood oxygen saturation. These episodes of decreased breathing, called "apneas" (literally, "without breath"), typically last 20 to 40 seconds. Individuals with OSA are rarely aware of difficulty breathing, even upon awakening. It is often recognized as a problem by others who observe the individual during episodes or is suspected because of its effects on the body. OSA is commonly accompanied with snoring. Some use the terms obstructive sleep apnea syndrome or obstructive sleep apnea-hypopnea syndrome to refer to OSA which is associated with symptoms during the daytime. Symptoms may be present for years or even decades without identification, during which time the individual may become ...
TY - JOUR. T1 - Computational fluid dynamics endpoints to characterize obstructive sleep apnea syndrome in children. AU - Wootton, David M.. AU - Luo, Haiyan. AU - Persak, Steven C.. AU - Sin, Sanghun. AU - McDonough, Joseph M.. AU - Isasi, Carmen R.. AU - Arens, Raanan. PY - 2014/1/1. Y1 - 2014/1/1. N2 - Computational fluid dynamics (CFD) analysis may quantify the severity of anatomical airway restriction in obstructive sleep apnea syndrome (OSAS) better than anatomical measurements alone. However, optimal CFD model endpoints to characterize or assess OSAS have not been determined. To model upper airway fluid dynamics using CFD and investigate the strength of correlation between various CFD endpoints, anatomical endpoints, and OSAS severity, in obese children with OSAS and controls. CFD models derived from magnetic resonance images were solved at subject-specific peak tidal inspiratory flow; pressure at the choanae was set by nasal resistance. Model endpoints included airway wall minimum ...
Over 22 million Americans suffer from sleep apnea. The causes and intensity of symptoms of sleep apnea vary person to person, so its important to be aware of the treatment options available. Fortunately, Mercy Health has a new treatment for those who suffer from Obstructive Sleep Apnea called the Inspire Therapy.. Medical Director of Sleep Medicine Dr. Christopher Morgan stopped by to explain what sleep apnea is, what symptoms to look out for, and the technology behind new treatment options.. Obstructive sleep apnea is a potentially serious sleep disorder, causing breathing to repeatedly stop and start during sleep. Symptoms include excessive daytime sleepiness, snoring, stopping breathing during sleep, insomnia, excessive nighttime urination, awakening with a dry mouth or sore throat, morning headache, high blood pressure and nighttime sweating.. Patients should treat their sleep apnea so they dont experience daytime fatigue and sleepiness, which can increase the risk for car accidents and ...
TY - JOUR. T1 - Depressive symptomatology in school-aged children with obstructive sleep apnea syndrome. T2 - Incidence, demographic factors, and changes following a randomized controlled trial of adenotonsillectomy. AU - Hodges, Elise. AU - Marcus, Carole L.. AU - Kim, Ji Young. AU - Xanthopoulos, Melissa. AU - Shults, Justine. AU - Giordani, Bruno. AU - Beebe, Dean W.. AU - Rosen, Carol L.. AU - Chervin, Ronald D.. AU - Mitchell, Ron B.. AU - Katz, Eliot S.. AU - Gozal, David. AU - Redline, Susan. AU - Elden, Lisa. AU - Arens, Raanan. AU - Moore, Renee. AU - Taylor, H. Gerry. AU - Radcliffe, Jerilynn. AU - Thomas, Nina H.. PY - 2018/12/1. Y1 - 2018/12/1. N2 - Study Objectives Depressive symptoms following adenotonsillectomy (AT) relative to controls were examined in children with obstructive sleep apnea syndrome (OSAS). Methods The Childhood Adenotonsillectomy Trial (CHAT) multisite study examined the impact of AT in 453 children aged 5 to 9.9 years with polysomnographic evidence of OSAS ...
Obstructive sleep apnea is a significant medical problem affecting up to 4 percent of middle-aged adults. The most common complaints are loud snoring, disrupted sleep and excessive daytime sleepiness. Patients with apnea suffer from fragmented sleep and may develop cardiovascular abnormalities because of the repetitive cycles of snoring, airway collapse and arousal. Although most patients are overweight and have a short, thick neck, some are of normal weight but have a small, receding jaw. Because many patients are not aware of their heavy snoring and nocturnal arousals, obstructive sleep apnea may remain undiagnosed; therefore, it is helpful to question the bedroom partner of a patient with chronic sleepiness and fatigue. Polysomnography in a sleep laboratory is the gold standard for confirming the diagnosis of obstructive sleep apnea; however, the test is expensive and not widely available. Home sleep studies are less costly but not as diagnostically accurate. Treatments include weight loss, nasal
Obstructive sleep apnea (OSA) is the most common category of sleep-disordered breathing. The muscle tone of the body ordinarily relaxes during sleep, and at the level of the throat the human airway is composed of collapsible walls of soft tissue which can obstruct breathing during sleep. Mild occasional sleep apnea, such as many people experience during an upper respiratory infection, may not be important, but chronic severe obstructive sleep apnea requires treatment to prevent low blood oxygen (hypoxemia), sleep deprivation, and other complications. The most serious complication is a severe form of congestive heart failure called cor pulmonale.[citation needed]. Individuals with low muscle tone and soft tissue around the airway (e.g., because of obesity) and structural features that give rise to a narrowed airway are at high risk for obstructive sleep apnea. The elderly are more likely to have OSA than young people. Men are more likely to suffer sleep apnea than women and children are, though ...
Obstructive sleep apnea hypopnea The pathophysiology of obstructive sleep apnea syndrome (OSAS) is poorly understood. Alterations exist in alveolar ventilation and oxygenation. OSAS is associated wit... more
Lifestyle modification, particularly weight loss, has been advocated as a treatment modality for obstructive sleep apnoea syndrome (OSAS). Surprisingly, there is a lack of well-conducted clinical trials; available studies have either been small and/or non-randomised. One reason could be that it has become popular to use devices such as continuous positive airway pressure (CPAP) or mandible retraction devices as mechanical tools rather than try to address the underlying problem, which generally is excess fatness in the throat area. In a report, from the International Diabetes Federation investigating the association between type 2 diabetes and sleep- disordered breathing, a number of recommendations were given. Apart from increased awareness and improved clinical practice the working party strongly suggested appropriately powered randomised control trials of weight loss in patients with OSAS and diabetes, including the use of anti-obesity medication. The party also suggest the development of ...
Authors: Wardly DE.. Obstructive sleep apnea has been shown to increase intracranial pressure, and to be a secondary cause of intracranial hypertension. There are a few theories that attempt to explain this relationship, however there is little data, and even less recognition among physicians that this actually occurs. This paper discusses multiple pieces of data, from anatomical correlates to biochemical information involving neuro-excitotoxicity, as well as hematologic factors and issues surrounding brain edema and blood-brain barrier dysfunction. A complex paradigm for how obstructive sleep apnea may lead to increased intracranial pressure is thus proposed. In addition, suggestions are made for how obstructive sleep apnea must as a result be managed differently in the setting of idiopathic intracranial hypertension.. ...
Continuous positive airways pressure (CPAP) is the most common treatment for obstructive sleep apnoea. It involves the use of a pump which delivers low pressure air into the airways via tubing and a mask fitted to the nose. It is worn during sleep and delivers enough pressure to keep the airway open during sleep. The amount of pressure required to maintain an open airway varies with each individual. If the results of the sleep study clearly indicate OSA, a CPAP machine is often applied and adjusted to the appropriate settings while the study is in progress. It may be necessary to return to the sleep clinic after the study to receive training on how to properly use the CPAP machine at home. Many people find they feel much better within a few days of commencing CPAP as they get the benefit of deep restorative sleep that they previously lacked.. Variations of positive airways pressure therapy devices are auto-titrating CPAP, in which the levels of pressure are adjusted if the device senses ...
The Federal Motor Carrier Safety Administration (FMCSA) and the Federal Railroad Administration (FRA) withdraw the March 10, 2016, advance notice of proposed rulemaking concerning the prevalence of moderate-to-severe obstructive sleep apnea (OSA) among individuals occupying safety sensitive positions in highway and rail transportation, and its potential consequences for the safety of highway and rail transportation.
1. Problems in the airway. Obstructive sleep apnea results from an obstruction in the airway, which is usually caused by certain problems in the airway components. These include the upper and lower jaws, tonsils, soft palate, tongue, and throat muscles. Some sleep apnea cases involve over-relaxed throat muscles and tongue. When a person sleeps, his muscles normally relax, but when his throat muscles and tongue relax more than normal, it results in narrowing of the airway and causes apneic events. Enlarged and collapsed soft palate and tonsils also cause obstructive sleep apnea. 2. Structural abnormalities. Anatomical abnormalities contribute to a persons tendency to experiencing obstructive sleep apnea. For instance, the bone structure and shape of the head and neck may affect the size of the airway. A thicker neck may mean narrower airway. Moreover, large tongue and tonsils may also have an effect on the air passage. There are also structural abnormalities in the jaw, nose, and mouth that ...
This study investigate the impact of anti hypertensive drugs in obstructive sleep apnea patients, i.e., whether or not obstructive sleep apnea may constitute
There are patterns of unusual facial features that occur in recognizable syndromes. Some of these craniofacial syndromes are genetic, others are from unknown causes. In many craniofacial syndromes, the features that are unusual involve the nose, mouth, and jaw, or resting muscle tone, and put the individual at risk for OSA syndrome. Down syndrome is one such syndrome. In this chromosomal abnormality, several features combine to make the presence of obstructive sleep apnea more likely. The specific features of Down syndrome that predispose to obstructive sleep apnea include relatively low muscle tone, narrow nasopharynx, and large tongue. Obesity and enlarged tonsils and adenoids, conditions that occur commonly in the western population, are much more likely to be obstructive in a person with these features than without them. Obstructive sleep apnea does occur even more frequently in people with Down syndrome than in the general population. A little over 50% of all people with Down syndrome ...
If these measures dont improve your sleep or if your apnea is moderate to severe, then your doctor may recommend other treatments. Certain devices can help open up a blocked airway. In other cases, surgery may be necessary.. Therapies: Positive airway pressure. If you have obstructive sleep apnea, you may benefit from positive airway pressure. In this treatment, a machine delivers air pressure through a piece that fits into the nose or is placed over the nose and mouth while you sleep. Positive airway pressure reduces the number of respiratory events that occur as you sleep, reduces daytime sleepiness and improves your quality of life.. The most common type is called continuous positive airway pressure, or CPAP (SEE-pap). With this treatment, the pressure of the air breathed is continuous, constant and somewhat greater than that of the surrounding air, which is just enough to keep your upper airway passages open. This air pressure prevents obstructive sleep apnea and snoring.. CPAP may be given ...
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This study aimed to assess the changes of RA function in patients with obstructive sleep apnea syndrome (OSAS) using velocity vector imaging (VVI) and to evaluate the application of VVI technology. According to the apnea-hypopnea index (AHI), 71 patients with OSAS were divided into three groups: mild, moderate, and severe. A total of 30 cases of healthy subjects were enrolled as the control group. Digital images of apex four-chamber views were acquired to measure the right atrium (RA) linear dimensions and volume parameters including RA longitudinal diameter (RAL), transverse diameter (RAT), RA maximum volume (Vmax), RA minimum volume (Vmin), right atrial volume before contraction (Vpre). Right atrial volume parameters were corrected by body surface area (VImax, VImin, VIpre). The total right atrial emptying fraction (RATEF), right atrial passive emptying fraction (RAPEF), right atrial active contraction emptying fraction (RAAEF) were calculated. The VVI data measuring right atrial global strain (RA-GLS
BACKGROUND Gender differences in the prevalence of various manifestations of obstructive sleep apnea syndrome (OSAS) is not as great as previously believed. The aim of the present study was to clarify the clinical patient characteristics of Japanese women and men with OSAS. METHODS A cross-sectional case-match control study was performed on patients from two sleep disorder centers. Two hundred forty-five women with OSAS were classified into premenopausal (n = 70) and postmenopausal (n = 175) groups. As well, 245 men matched for both age and apnea-hypopnea index (AHI) and another 245 men matched for age and body mass index (BMI) were established. We compared descriptive variables between genders in both the premenopausal and the postmenopausal female patient groups. RESULTS As a whole, female patients had significantly higher BMI than AHI-matched male patients (p | 0.05) and a significantly lower value of AHI than BMI-matched male patients (p | 0.001). Female patients had lower Epworth Sleepiness
Sleep-disordered breathing (SDB) disorders include: central sleep apnoea (Cheyne-Stokes respiration), obstructive sleep apnoea and mixed or complex sleep apnoea. Obstructive sleep apnoea (OSA) is the most common of these three disorders and is defined as airway obstruction during sleep, accompanied by at least five episodes of apnoea or hypopnoea per hour. Each episode is often associated with a decrease in arterial oxygen saturation of > 4%.
Background: Childhood obstructive sleep apnoea (OSA) is suggested to be associated with cardiac structural abnormalities and dysfunction but existing evidence are limited and the treatment effect on echocardiographic outcome remains controversial. Objective: To examine for the presence of subclinical cardiac abnormalities in childhood OSA and the effects of treatment on cardiac changes. Methods: Polysomnography (PSG) and echocardiographic examinations were performed on 101 children aged between 6 and 13 years were invited from a community based questionnaire survey. They were classified into reference group (Apnoea-hypopnoea index (AHI),1, n=35), mild OSA group (AHI 1-5, n=39) and moderate-to-severe group (AHI,5, n=27) based on PSG result. Treatments including adenotonsillectomy or nasal steroid were offered to the mild and moderate-to-severe OSA group. Results: Moderate-to-severe OSA group had greater right ventricular (RV) systolic volume index (RVSVI), lower RV ejection fraction (RVEF) and ...
Obstructive sleep apnea, which is literally the stoppage of breaths during sleep, happens when there is an obstruction in the airway. Although the breath pauses normally last for 10 to 30 seconds, they happen on average 30 times an hour. The effects obstructive sleep apnea has on health put people in great danger. This is why necessary treatments, including sleep apnea surgery, have been designed to correct the obstructions in the airway, which involve the jaws, tonsils, soft palate, and tongue.. Surgical operations are normally done to treat severe sleep apnea, although a few are developed for mild to moderate cases. The severity of the case, however, dictates the degree of the invasiveness of the surgical procedure. The more severe sleep apnea is, the more invasive the surgery is. The cause of sleep apnea is a major consideration in determining which surgery to perform. Yet, the personal preference and medical condition of the patient are also factors. Though some surgeries can stand alone as ...
The snoring in people with obstructive sleep apnea is caused by the air trying to squeeze through the narrowed or blocked airway. Some patients have obstructions that are less severe called Upper Airway Resistance Syndrome (UARS). In either case, the individuals suffer many of the same symptoms.. A person who has obstructive sleep apnea often is not aware of the apnea episodes during the night. Often, family members witness the periods of apnea.. A person with obstructive sleep apnea usually begins snoring heavily soon after falling asleep. Often the snoring gets louder. The snoring is then interrupted by a long silent period during which there is no breathing. This is followed by a loud snort and gasp, as the person attempts to breathe. This pattern repeats. People with obstructive sleep apnea may not be aware that their sleep was interrupted. In fact, many people with this type of sleep apnea think they slept well all night.. Many people wake up unrefreshed in the morning and feel sleepy or ...
Over the last decade, oral appliance use for the treatment of snoring, mild obstructive sleep apnea and for those patients who are intolerant of nasal continuous positive airway pressure has increased significantly. Obstructive sleep apnea is a progressive disease with serious cardiovascular and mortality consequences. The increased mortality is due not only to the progression of cardiovascular disease but also to judgement errors made while driving or operating machinery a result secondary to the excessive daytime sleepiness commonly seen in these patients. Canadian research has provided a significant amount of new knowledge in the field of obstructive sleep apnea. Recent findings have significantly increased our knowledge of how oral appliances should be used and which appliances are best suited to different patients.1,2 Titratable appliances, such as the 2 devices described by Dr. Tyler, allow for incremental advances of the mandible and permit some degree of lateral and vertical jaw ...
Multivariate analysis. We found that age had a significant between subjects effect in Total sleep time (F = 4.08, p = 0.04). On the other hand we found that BMI had significant between subjects effects in Total sleep time (F = 3.27, p = 0.04), Sleep latency (F = 5.47, p = 0.006), Electroencephalographic activations (F = 8.38, p , 0.001), AHI (F = 22.00, p , 0.001), mean oxygen saturation (F = 4.89, p = 0.009), and minimum oxygen saturation (F = 3.91, p = 0.02).. DISCUSSION. Our main finding of this study was that SA is worst disrupted in police officers on NSW and OSAHS than in patients with OSAHS only and control subjects. Our three groups design allowed us to measure how the additive effect of NSW and OSAHS results in more SA and SQ alterations. Alterations were influenced mainly by BMI.. Night shift workers experienced several troubles such as a circadian disruption, increased frequency of sleep disorders, and social and family issues [3]. Searching for better work conditions, the Work ...
Multivariate analysis. We found that age had a significant between subjects effect in Total sleep time (F = 4.08, p = 0.04). On the other hand we found that BMI had significant between subjects effects in Total sleep time (F = 3.27, p = 0.04), Sleep latency (F = 5.47, p = 0.006), Electroencephalographic activations (F = 8.38, p , 0.001), AHI (F = 22.00, p , 0.001), mean oxygen saturation (F = 4.89, p = 0.009), and minimum oxygen saturation (F = 3.91, p = 0.02).. DISCUSSION. Our main finding of this study was that SA is worst disrupted in police officers on NSW and OSAHS than in patients with OSAHS only and control subjects. Our three groups design allowed us to measure how the additive effect of NSW and OSAHS results in more SA and SQ alterations. Alterations were influenced mainly by BMI.. Night shift workers experienced several troubles such as a circadian disruption, increased frequency of sleep disorders, and social and family issues [3]. Searching for better work conditions, the Work ...
This is the business view business. Obstructive sleep apnea (OSA) or obstructive sleep apnea syndrome is the most common type of sleep apnea and is caused by obstruction of the upper airway. It is characterized by repetitive pauses in breathing during sleep, despite the effort to breathe, a...
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TY - JOUR. T1 - Cosmetic enhancement associated with surgery for obstructive sleep apnea. AU - Terris, David J. PY - 1999/1/1. Y1 - 1999/1/1. N2 - Objective:To document the capacity of surgery for obstructive sleep apnea (OSA) to incorporate techniques that incidentally improve the cosmetic features of the patients.Study Design:Retrospective analysis of surgical outcomes at an academic practice.Methods:Moderate to severe OSA usually requires multilevel pharyngeal surgery, including tongue base surgery. The surgical procedures, including hyoid myotomy and mandibular osteotomy with tongue advancement, afford the opportunity to address cosmetic deficits, such as microgenia and excessive submental skin and fat. Outcomes achieved using these procedures over a 4-year period were analyzed.Results:Of 428 consecutive patients presenting for evaluation of sleep-related breathing disorders, 212 were deemed surgical candidates. Ninety-seven of these had office-based procedures for snoring, upper airway ...
SDB (Sleep-disordered breathing) is a group of medical conditions that are characterized by abnormalities in the quality or pattern of respiratory activity. These include snoring, UARS (upper airway resistance syndrome), and OSA (obstructive sleep apnea).. All of these conditions involve the restriction of the airway. With snoring and upper respiratory resistance syndrome, the airway is partially blocked. It is important to address these conditions before they become apnea, which can have much more serious consequences.. Obstructive sleep apnea is characterized by pauses in breathing, known as apneic events. During these events, the blood oxygen level drops, triggering "fight or flight response," that is responsible for releasing adrenalin, raising blood pressure, and increasing heart rate. The patient rarely awakens fully during these events, and therefore is not consciously aware that breathing stopped. However, he or she experiences the same physiological effects that accompany panic, ...
The findings of a study published Wednesday, October 29, in the Journal of Neuroscience suggest that the sleep disorder sleep apnea may be responsible for worsening the memory of those who suffer from it.. According to WebMD, sleep apnea occurs when a persons breathing is interrupted during sleep. That disruption can result in depriving the brain of a sufficient amount of oxygen, which may have a negative impact on brain health. In individuals with the disorder, breathing can be interrupted up to 400 times every night for 10 to 30 seconds at a time.. Clinical instructor Dr. Andrew Varga of the NYU Langone Medical Center led a team of researchers who studied 18 participants with severe obstructive sleep apnea (OSA). The participants sleep was studied over two nights. First, the individuals were treated using continuous positive airway pressure (CPAP) through the night. The second night, CPAP was reduced during REM sleep to allow for OSA.. The resulting data showed that when REM, or rapid eye ...
Adults with obstructive sleep apnea (OSA) who experience excessive sleepiness while awake appear to be at far greater risk for cardiovascular diseases than those without excessive daytime sleepiness, according to new research published online in the American Thoracic Societys American Journal of Respiratory and Critical Care Medicine.. In "Symptom Subtypes of Obstructive Sleep Apnea Predict Incidence of Cardiovascular Outcomes," Diego R. Mazzotti, PhD, and coauthors report on a study of adults with moderate to severe OSA who were categorized into 4 subtypes according to the symptoms they report: disturbed sleep, minimally symptomatic, moderately sleepy, and excessively sleepy.. Previous studies have linked OSA and cardiovascular disease. To understand this association better, researchers have begun to categorize patients with OSA based on their symptoms.. "Multiple studies from our group have shown that patients with moderate to severe OSA throughout the world can be categorized into specific ...
... can be characterized by recurrent episodes of upper airway obstruction during sleep. They are commonly associated with the so called recurrent oxyhemoglobin desaturation and frequent arousals from sleep. The term obstructive sleep apnea-hypopnea syndrome (OSAHS) is frequently used when such episodes are associated with excessive daytime sleepiness.. The majority of patients with obstructive sleep apnea-hypopnea syndrome demonstrate upper airway obstruction, either at the level of the soft palate or at the level of the tongue. Anatomic factors include enlarged tonsils, macroglossia, or abnormal positioning of the maxilla and mandible. They decrease the cross-sectional area of the upper airway and increase the pressure surrounding the airway, both of which predispose the airway to collapse.. Upper airway neuromuscular activity decreases with sleep, that is more pronounced in patients with sleep apnea or hypopnea. Reduced ventilatory motor output to upper airway muscles is believed to be ...
Smith, SS, Hopkins, W, Sullivan, K and Douglas, J (2003). Prevalence of insomnia in patients with obstructive sleep apnea syndrome (OSAS). In: Sleep. 17th Annual Meeting of the Associated-Professional-Sleep-Societies, Chicago Illinois, (A292-A292). Jun 03-08, 2003. ...
1. Chest. 2013 May;143(5):1284-93. doi: 10.1378/chest.12-1132. Serum bicarbonate level improves specificity of STOP-bang screening for obstructive sleep apnea. Chung F, Chau E, Yang Y, Liao P, Hall R, Mokhlesi B. Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada. [email protected] BACKGROUND: The STOP-Bang questionnaire is a validated screening tool for the identification of surgical patients with obstructive sleep apnea (OSA). A STOP-Bang score ≥ 3 is highly sensitive but only moderately specific. Apnea/hypopnea during sleep can lead to intermittent hypercapnia and may result in serum bicarbonate (HCO₃⁻) retention. The addition of serum HCO₃⁻ level to the STOP-Bang questionnaire may improve its specificity. METHODS: Four thousand seventy-seven preoperative patients were approached for consent and screened by the STOP-Bang questionnaire. Polysomnography was performed and preoperative HCO₃⁻ level was ...