About Skull Base Tumors The brain originates the most crucial functions of the body - everything from muscle movement to eating, breathing, feeling pain and emotion. Skull base tumors can affect nearly every one of these functions in the brain. These tumors are rare, and cancerous skull base tumors are even less common.
Palliative RT has been the standard treatment for skull base malignancies providing excellent relief of pain and improvement of cranial nerve dysfunction in up to 78% of patients [4-9]. More recently, SRS has been employed as a less invasive option for the treatment of skull base metastases with the aim to deliver a high dose to the target with dose sparing of critical structures such as the optic nerves and chiasm. The efficacy of single-fraction SRS for skull base metastases has been reported in few studies that include either nasopharyngeal carcinomas or skull base metastases [14-17]. Iwai et al. [15] treated 21 patients with cavernous sinus cancers, including 12 patients with metastases from systemic cancer. At a median follow-up of 13 months, the 1-year and 2-year tumor control rates were 68% and 47%, respectively, with no significant differences between nasopharyngeal carcinoma and metastases. After SRS, there was a resolution or improvement of preoperative cranial nerve deficits in 47% of ...
Preservation of anatomic integrity and function of the cranial nerves during the removal of skull base tumors is one of the most challenging procedures in endoscopic endonasal surgery. It is possible to use intraoperative mapping and identification of the cranial nerves in order to facilitate their preservation. The purpose of this study was to evaluate the effectiveness of intraoperative trigger electromyography in prevention of iatrogenic damage to the cranial nerves. Twenty three patients with various skull base tumors (chordomas, neuromas, pituitary adenomas, meningiomas, cholesteatomas) underwent mapping and identification of cranial nerves during tumor removal using the endoscopic endonasal approach in Department of Neurooncology of Federal State Autonomous Institution
Dr. Stephanie is Chicagos Skull Base Tumor specialist. Endoscopic resection involves the use of telescopes and cameras through the nose the reach the tumor and remove it. This type of surgery is used to avoid disfiguring external skin incisions to remove the skull based tumor.
Our Head and Neck Cancer team is made up of specialists across multiple disciplines who work together to accurately diagnose benign and malignant skull base tumors.
Endonasal Endoscopic Surgery of Skull Base Tumors: An Interdisciplinary Approach This book presents a complete step-by-step guide to endonasal endoscopic skull base surgery, written by prominent interdisciplinary specialists and reflecting important recent developments in the field. Combining the fundamentals of skull
TY - JOUR. T1 - Skull base tumor model. AU - Gragnaniello, Cristian. AU - Nader, Remi. AU - Van Doormaal, Tristan. AU - Kamel, Mahmoud. AU - Voormolen, Eduard H J. AU - Lasio, Giovanni. AU - Aboud, Emad. AU - Regli, Luca. AU - Tulleken, Cornelius A F. AU - Al-Mefty, Ossama. PY - 2010/11. Y1 - 2010/11. N2 - Object. Resident duty-hours restrictions have now been instituted in many countries worldwide. Shortened training times and increased public scrutiny of surgical competency have led to a move away from the traditional apprenticeship model of training. The development of educational models for brain anatomy is a fascinating innovation allowing neurosurgeons to train without the need to practice on real patients and it may be a solution to achieve competency within a shortened training period. The authors describe the use of Stratathane resin ST-504 polymer (SRSP), which is inserted at different intracranial locations to closely mimic meningiomas and other pathological entities of the skull ...
Dr. Arthur Wu is a fellowship trained Rhinologist and Los Angeles Skull Base Tumor Resection Surgeon who has extensive experience in these techniques.
Dr. Arthur Wu is a respected Los Angeles Skull Base Tumor Surgeon and provides exceptional patient care and cutting-edge ENT services. Call (310) 423-1220
See the causes of skull base tumors to determine if you are at risk for this life threatening condition. Schedule an appointment for diagnosis today.
Pelisyonkis Langone doctors may use results of imaging tests, an angiogram, and sometimes a biopsy to diagnose skull base tumors. Learn more.
We report a case of an acute spontaneous epidural hematoma (EDH) due to skull base metastasis in a 46-year-old male patient with hepatocellular carcinoma (HCC). The patient presented with the acute onset of severe headache followed by unconsciousness, and computed tomography showed a large EDH in th...
Management of Recurrent Skull Base Meningiomas Keywords: anaplastic, atypical, chemotherapy, endoscopic surgery, meningioma, microsurgery, minimally-invasive, radiosurgery, recurrence, skull base Sheri K. Palejwala, Garni Barkhoudarian, Walavan Sivakumar, Daniel F. Kelly Abstract Skull base meningiomas, due to their frequent investment or encasement of critical neurovascular structures, are challenging to resect in their entirety, both with initial resection…
Our UCI Health skull base surgery team is experienced at diagnosing and treating the broad range of malignancies that can affect the skull base region. For more information or to schedule a consultation, call us at 714-456-7713 or 714-456-6966.
Our UC Irvine Health skull base surgery team is experienced at diagnosing and treating the broad range of malignancies that can affect the skull base region. For more information or to schedule a consultation, call us at 714-456-7713 or 714-456-6966.
Meningioma is a primary central nervous tumour (CNS) affecting mostly adults. Skull base meningiomas cause morbidity (and occasionally mortality) by compressing adjacent critical organs, and the aim of treatment is to optimise and preserve CNS function. Radiotherapy is an effective treatment for meningioma, with doses of 50-54Gy in conventional fractionation schedules resulting in long-term local control rates of 80-90%. However, local recurrence is unacceptably high in aggressive histological subtypes (WHO G2 and G3), and these patients have a poor outcome following standard dose regimens. In recent years Intensity-Modulated Radiotherapy (IMRT) has been developed, and can deliver highly conformal dose distributions with sharp dose gradients, making dose escalation a possibility for many tumours, including those located in the skull base. The aim of this thesis was to address two issues pertaining to the role of radiotherapy for skull base meningioma. Firstly the goal was to investigate the ...
Elias Michaelides, MD, is a neurotologist and skull base surgeon who provides compassionate support and advanced surgical care for patients with lateral skull base tumors and tumors of the ears and temporal bone. He received a BA for Cornell University and his MD from SUNY-Stony Brook. He completed a residency in Otolaryngology/Head and Neck Surgery at the Medical College of Virginia. After completing a Fellowship in Otology, Neurotology, and Skull Base Surgery at the Michigan Ear Institute, he stayed on as faculty there for four years. Dr. Michaelides provides comprehensive care of skull base tumors and other tumors of the ear.. ...
Elias Michaelides, MD, is a neurotologist and skull base surgeon who provides compassionate support and advanced surgical care for patients with lateral skull base tumors and tumors of the ears and temporal bone. He received a BA for Cornell University and his MD from SUNY-Stony Brook. He completed a residency in Otolaryngology/Head and Neck Surgery at the Medical College of Virginia. After completing a Fellowship in Otology, Neurotology, and Skull Base Surgery at the Michigan Ear Institute, he stayed on as faculty there for four years. Dr. Michaelides provides comprehensive care of skull base tumors and other tumors of the ear.. ...
TY - JOUR. T1 - Skull base meningiomas. AU - Couldwell, William T.. AU - Heros, Roberto. AU - Dolenc, Vinko. PY - 2011/5. Y1 - 2011/5. UR - http://www.scopus.com/inward/record.url?scp=84858619086&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84858619086&partnerID=8YFLogxK. U2 - 10.3171/2011.3.FOCUS1185. DO - 10.3171/2011.3.FOCUS1185. M3 - Editorial. C2 - 21529181. AN - SCOPUS:84858619086. VL - 30. JO - Neurosurgical Focus. JF - Neurosurgical Focus. SN - 1092-0684. IS - 5. ER - ...
The Skull Base, upon which the Brains undersurface rests, has three main regions. The Anterior (front) Cranial Fossa is the region located above the eyes and includes structures such as: the Olfactory Bulbs, the Nasal Cavity, and Cranial Nerves (1 & 2 and sections of 3, 4 & 6) that control vision, as well as movement of the eyeballs. The Middle Cranial Fossa is the region containing the dense, boney Petrous Ridge, and houses the Internal Carotid Artery, along with sections of the Cranial Nerves (5 & 7) that control chewing and facial sensation. The Middle Cranial Fossa also contains the Cavernous Sinus, an extremely difficult structure from which to remove tumors. The Posterior (back) Cranial Fossa is where the Internal Auditory Canal (IAC) and the Cranial Nerves (7 & 8) responsible for hearing, facial expression and balance are located; the Jugular Vein also passes through this region. Of the 24 highly specialized Cranial Nerves, which control many vital functions of our head and neck, 18 ...
To evaluate the impact of 68Ga-DOTATOC-PET on treatment planning and sparing of normal tissue in the treatment of skull base meningioma with advanced photons and protons. From the institutional database consisting of 507 skull base meningiomas 10 patients were chosen randomly for the present analysis. Target volume definition was performed based on CT and MRI only, as well as with additional 68Ga-DOTATOC-PET. Treatment plans were performed for Intensity Modulated Radiotherapy (IMRT) and proton therapy using active raster scanning on both target volumes. We calculated doses to relevant organs at risk (OAR), conformity indices as well as differences in normal tissue sparing between both radiation modalities based on CT/MRI planning as well as CT/MRI/PET planning. For photon treatment plans, PET-based treatment plans showed a reduction of brain stem Dmax and Dmedian for different levels of total dose. At the optic chiasm, use of 68Ga-DOTATOC significantly reduces Dmax; moreover, the Dmedian is reduced in
I had a pituitary macro adenoma (acromegaly) removed at UPMC in 2005 with Gamma Knife follow-up in 2006. In 2008, I was diagnosed with Parkinsons Disease and in 2010, had a T12 compression fracture. ...
prolactin level 76. MRI found a 2x3mm tumor on the pituitary. My biggest problem is a weight gain of 13 lbs in a matter of months. I do athletic training with a trainer 3-4 times a week, eat a low carb...
Since 1910, Swedish has been the Seattle areas hallmark for excellence in hospitals and health care. Swedish is consistently named the Seattle areas best hospital, with the best doctors, nurses and overall care in a variety of specialty areas. Learn more. ...
Giant cell tumours (GCT) of the skull base account for approximately 1% of all GTC of the bone. Despite being considered as a benign neoplasm, they are locally aggressive with high recurrence rates after incomplete surgery. Due to the small number of cases reported in skull base, standardized treatment remains unclear. Even with new surgical techniques, a complete resection in skull base tumours is not always possible without functional compromise. Therefore, adjuvant therapy is essential to enhance local control and quality of life. We described a case treated successfully with primary surgery followed by Cyberknife stereotactic radiosurgery (SRS) and denosumab with a 48-month follow-up. To the best of our knowledge, the usage of combined therapy, SRS and denosumab, in skull base GCT has not been previously described.
MORALES, F. et al. Skull base meningiomas: a predictive system to know the extent of their surgical resection and patient outcome. Neurocirugía [online]. 2005, vol.16, n.6, pp.477-485. ISSN 1130-1473.. Objective. The aim of this study was to build a preoperative predictive system which could pro-vide reliable information about: 1° which skull base meningiomas can be total or partially removed, and 2° their surgical outcome. Method. Patient histories and imaging data were reviewed retrospectively from 85 consecutive skull base meningiomas patients who underwent surgery from 1990 and 2002. From the preoperative data, nine variables were selected for conventional statistical analysis as regards their relationship with: 1° total vs partial tumor resection and 2° with patients outcome according to the degree of tumour removal. Results. From the nine variables analysed only two had a statistical association with the type of tumour resection performed (total vs partial) and the patient outcome: 1) ...
Course Directors: Evandro de Oliveira, MD, PhD., Rabih G. Tawk, M.D. and Christina C. Smith, ARNP This course is designed as a review of surgical approaches and operative techniques pertaining to surgical treatment of skull base lesions such as skull base tumors, cerebral aneurysms, and other disorders. This course is designed for neurosurgery medical providers at various stages of their careers including residents, fellows, attendings and neurosurgery team members, including nurse practitioners and physician assistants.to provide a global approach to the skull base. It combines microscopic techniques with a simulated micro-anastomosis training session to improve microsurgical skills. The course will incoporate intensive hands-on cadaver dissection sessions, covering a broad spectrum of transcranial approaches and participants will work in teams on prepared injected fixed specimens under the guidance of a distinguished expert faculty.. *PLEASE NOTE: THIS COURSE WILL NOT OFFER CME CREDIT. ...
Background: The supraorbital keyhole approach has been used in anterior skull base tumor and aneurysm surgery. However, there are debates regarding the safety and limitations of this kind of approach. Objective: To determine the feasibility and potential benefits of surgical robotic technology in minimally invasive neurosurgery. Methods: Two fresh cadaver heads were studied with the…
The authors report a novel technique of balloon-assisted embolization of a skull base meningioma supplied by a branch of the cavernous segment of the internal carotid artery using liquid embolic agent. A temporarily inflated balloon distal to the meningiomas feeding vessel may improve the access to this small branch and may reduce the chances of unintended reflux during delivery of the liquid embolic agent. ...
At Morristown Medical Centers Skull Base Surgery Program, we believe that the timely, accurate diagnosis of skull base tumors results in more effective treatments and speedier recoveries.
Pamela Jones, MD MS MPH, is a neurosurgeon who cares for people with all types of brain tumors, including glioblastoma, low and high-grade gliomas, metastatic brain tumors, and skull base tumors such as meningiomas and pituitary tumors. Her expertise includes performing minimally-invasive endoscopic neurosurgery for treating tumors in the skull base and pituitary. She also specializes in the treatment of brain tumors affecting the language and motor areas of the brain that may require awake brain surgery, language and motor mapping, and subcortical stimulation. Dr. Jones was thrilled to return to the MGH in 2017 after being an assistant professor at UCSD with a clinical practice focused in neuro-oncology and skull base disease. Dr. Jones completed residency training in neurosurgery at the Massachusetts General Hospital. Her fellowship training in pituitary and endoscopic skull base was also performed at the Massachusetts General Hospital and the Massachusetts Eye and Ear Infirmary under Dr. ...
Dr. Ahmed specializes in surgery for complex skull base tumors (meningiomas, pituitary adenomas, and acoustic neuromas), cerebrovascular disorders and neuroendovascular surgery. He also works closely with ear, nose and throat physicians for endoscopic skull base surgery. Some of Dr. Ahmeds research was directed at improving visualization for neuroendovascular procedures. The main goal of this research was to streamline stroke care and assist with clinical decision making while developing a user-friendly interface.. ...
The research focus of Adam N. Mamelak, MD, is pituitary tumor and endoscopic skull base surgery technical development. He is developing and testing new equipment and methods for minimally invasive surgery of pituitary and skull base tumors, and studying the pathogenesis of these tumors. He is also interested in neural basis of learning and memory through studying the neuro-physiological basis of memory processes in patients with implanted electrodes for identification of seizures or undergoing deep brain stimulation. Mamelak is looking into fluorescent guided removal of brain tumors.. View NIH Biographical Sketch as a PDF. ...
G. Michael Lemole, Jr., MD is Professor of Surgery and Chief of the Division of Neurosurgery at the University of Arizona (UA) Department of Surgery and Banner University Medical Center- Tucson. Dr. Lemole has expertise in all aspects of skull base disease including minimally-invasive endoscopic techniques, classical approaches, and radiosurgical treatments. He serves as co-director of the UA Center for Sinonasal and Skull Base Tumors. He recently completed his term as Chief of Staff at the University of Arizona Medical Center Hospital (Main Campus). Dr. Lemoles clinical interests include diseases of the cranial base. His focus is on creating multidisciplinary teams of surgeons and specialists who collaborate to offer the full range of cutting-edge surgical, radiosurgical, and medical treatments for patients with brain and spine disorders. Dr. Lemole received his undergraduate degree from Harvard University and his medical degree from the University of Pennsylvania. He completed his residency ...
Administration of doxycycline in drinking water for treatment of spiral bacterial infection in cockatiels. Prolonged focal cerebral edema associated with real cialis without a doctors prescription partial status epilepticus. Despite the small size of craniotomy the superciliary approach is a suitable technique for resection of skull base tumors in the anterior fossa, orbit, sellar, parasellar and suprasellar regions.. This study was to investigate the acute change of LA activation, voltage and P wave in surface electrocardiogram (ECG) after CPVI. Importance of basic residues in binding of rous online cialis without subscription sarcoma virus nucleocapsid to the RNA packaging signal. In our clinical study, 101 of the 103 flaps (98.1 percent) were (vascular-pedicled) island flaps and five (4.9 percent) were transferred under a skin natural cialis tunnel. Effect of levosimendan on myocardial contractility, coronary and peripheral blood flow, and arrhythmias during coronary artery ligation and ...
Chondroid tumors are predominantly lesions of the axial skeleton but can infrequently have an extraskeletal origin. Primary intracranial chondrosarcomas constitute ,0.16% of all brain tumors, an overwhelming majority of which are skull base tumors (1, 2). They are thought to arise from undifferentiated cells from cartilaginous synchondroses (1-3, 6, 7). Much less common sites include the falx, choroid plexus, and convexity. The histogenesis at this site is uncertain but is thought to arise from the pluripotent cells of the meninges.. Primary chondrosarcomas can be classified as mesenchymal, myxoid, or classical based on their cytoarchitecture. In the series published by Korten et al (2), which included 15 case reports plus 177 cases from a review of the literature, no sex dominance was shown. Ages varied from 3 months to 76 years, with a mean age of 37 years. Considering the rarity of occurrence of intracranial chondrosarcomas, it was difficult to establish a clear demographic pattern; however, ...
Minimal invasive Neurosurgery (MIN) is an integral patient tailored treatment strategy. It does not simply mean to use smaller craniotomies or skin incisions. It includes beside the utilization of keyhole craniotomies also a meticulous and individual planning of the particular surgery as well as application of the latest technology.. MIN approaches are not called keyhole approaches because of the shape or absolute size of the craniotomy. They rather are call that way because of the fact, that one may well oversee all objects distant to a keyhole, even if they are much bigger than the hole itself. In contrast, even small objects very close or direct in front of a keyhole cannot be sufficiently visualized. This implies, that large but deep seated lesions such as skull base tumors or intraventricular pathologies may be perfectly visualized and treated whereas same sized lesions on the surface require openings equaling the size of the lesion itself.. ...
Mr Richard Kerr qualified from The London Hospital, and trained in surgery and neurosurgery in London, Oxford and Melbourne. Based at the John Radcliffe Hospital in Oxford, he has been consultant for 30years. With a wide cranial and spinal practice, he has subspecialty interests in skull base tumours, oncology and vascular disease. He devised and…
Tumors of the brain other than, chiasmal region, including middle and posterior skull base tumors ,exophytic brain stem tumors transcallosal , far lateral posterior fossa approach and the subtemporal transtentorial route with its different variations, here included the transoral approach with its different ...
Dr. Schirmer earned his medical degree and a doctorate in medical research from Ludwig-Maximilians University in Munich and at Harvard Medical School under the auspices of the Harvard Munich Alliance for Medical Education. He then completed his residency in neurosurgery and a fellowship in interventional neuroradiology at the Tufts Medical Center program in Boston. Board certified in neurological surgery and holding Committee on Advanced Subspecialty Training (CAST) certificates in neuroendovascular surgery and neurocritical care, he serves as the system director of cerebrovascular and endovascular neurosurgery and as co-director of the Geisinger Stroke Center at Geisinger Health System in Pennsylvania, specializing in the treatment of vascular disorders of the brain and spine using surgery, endovascular and radiation modalities. Neurosurgical trauma, brain and skull base tumors are his other neurosurgical interests. His research interests focus on the fluid dynamics of intracranial vascular ...
Isaac Yang M.D. was born in Chicago Illinois to his South Korean parents who had recently emigrated to the United States. He grew up in Lodi, California, and completed his undergraduate education with Phi Beta Kappa from the UC Berkeley and received his medical degree from UCLA. After graduating from medical school with AOA honors, he completed his general surgical internship and neurosurgical residency at the UCSF Medical Center in San Francisco. During residency, he performed an NIH funded brain tumor fellowship at the UCSF Brain Tumor Research Center. Upon completion of residency with the UCSF Medical Center Exceptional Physician Award, he joined the UCLA Department of Neurosurgery and the UCLA Brain Tumor Center. Dr. Yang s clinical focus has been primarily on brain tumors both glioblastoma and skull base tumors. His research efforts have examined antigen expression and manipulation of the immune response to glioblastoma. His efforts were recognized by the American Association of ...
Welcome to Dr. Siddhartha Ghosh website.. Dr. Siddhartha Ghosh, Senior Consultant Neurosurgeon and his team provide the highest quality and state-of-art medical and surgical care in this highly specialized field of neurosurgery.. On an average, he operates over 500 cases yearly, out of this, 300 cases are major that includes complicated brain tumors, skull base tumors, aneurysms, AVMs and other neurovascular disorders.. ...
Jeffrey A. Fearon, M.D., F.A.C.S., F.A.A.P.. Dr. Jeffrey Fearon is the primary provider for Craniofacial Plastic Surgery for Adult and Pediatric patients who are referred to Neurosurgical Consultants with Complex Skull Base Tumors.. Dr. Fearon was born in the United States, grew up in London, England, and New Canaan, Connecticut. After graduating from the Mt. Hermon School in Massachusetts, he received his B.A. from Brown University. He pursued his post-baccalaureate studies at Columbia University in New York, and attended medical school at the University of Cincinnati. He completed a full six-year general surgery residency at the Deaconess/Harvard Fifth surgical service in Boston, and a plastic surgery residency at the Massachusetts General Hospital; both associated with Harvard Medical School. After a one-year fellowship with the Childrens Hospital of Philadelphia at the University of Pennsylvania, he joined the Dallas Craniofacial Center as a director. His practice is focused on the ...
Oligoastrocytoma. Oligodendroglioma. Pineoblastoma. Pineocytoma. Pituicytoma. Pituitary Tumor. Primary CNS Lymphoma. Primitive Neuroectodermal Tumor (PNET). Rhabdomyoma. Rhabdomyosarcoma. Salivary Gland Tumor. Sarcoma. Schwannoma. Sinonasal Carcinoma. Skull Base Tumor. Spinal Tumor. Squamous Cell Carcinoma. Subependymoma. Teratoma. ...
Each chapter provides a concise description of useful pearls and, especially, dangerous pitfalls which must be avoided. Contributions cover topics from thyroid glands, neck metastases, and oral tumors to laryngeal, pharyngeal, nasopharyngeal tumors and further to salivary gland tumors, skull base tumors and also reconstructional surgery. In addition to frequent diseases which are encountered in everyday practice, some new therapeutic topics such as videoassisted thyroidectomy, robotic surgery and management of the neck after organ preservation treatment are discussed ...
Toral R. Patel, M.D. Patel UT Southwestern Medical Center Dallas TX United States The American Board of Neurological Surgery Neurological Surgery, Neurosurgical Oncology Pituitary Tumors, Skull Base Tumors, Intra-Axial Brain Tumors, Gliomas, Brain Mapping The Pituitary Network Association is an international non-profit organization for patients with pituitary tumors and disorders, their families, loved ones, and the physicians and health care providers who treat them.
Traditionally, carotid endarterectomy belonged to vascular surgeons in our hospital, but the tendency of conversion from conventional carotid endarterectomy to endovascular PTA and/or stenting seemed to be marked, while microvascular revascularization procedure represented by extracranial intracranial EC-IC bypass remained constant (around 20/year) in various occasion (277 times on 203 cases: atherosclerosis 93, Moyamoya angiopathy (MMA) 47, aneurysm 57 and skull base tumour 6, during the last 13 years], in spite of negative results of EC-IC bypass international cooperative study for stroke prevention in 1985 ...
Dr. Dutcher has specialized in otology/neurotology since he joined the University of Rochester Medical Centers faculty in 1983, where he serves as Director of the Otology Center of Western New York. His particular areas of expertise include disorders of the ear and hearing, disorders of balance and dizziness, malformations of the ear, hearing and hearing loss and cochlear implantation, and management of tumors involving the ear, including acoustic neuroma, glomus tumors, and other skull base tumors. ...
In keyhole brain surgery, a neurosurgeon removes the skull base tumor through a small incision behind the ear, providing access to the cerebellum and brainstem.
Keyhole surgery is the concept of safely removing brain & skull base tumors through smaller, more precise openings that minimize collateral damage. Read On