DYSCHROMATOSIS UNIVERSALIS HEREDITARIA 1; DUH1 description, symptoms and related genes. Get the complete information in our medical search engine for
Reticulate pigmentary disorders comprise a group of congenital and acquired conditions with reticulate or freckle-type hyperpigmentation and occasional hypopigmentation. There is some confusion in the literature with respect to definitions and terminology. Hereditary forms are unusual and have variable inheritance patterns, although they are generally autosomal dominant, with possible associated abnormalities. They include dyskeratosis congenita, Dowling-Degos disease, RAPK, Haber syndrome, reticulate acropigmentation of Dohi, Naegeli-Franceschetti-Jadassohn syndrome, X-linked reticulate pigmentary disorder, and dyschromatosis universalis hereditaria. In the acquired forms, the lesions are usually larger and include confluent and reticulate papillomatosis (Gougerot-Carteaud), prurigo pigmentosa, lichen planus pigmentosus, Riehl melanosis, erythema ab igne, cutis marmorata, livedo reticularis, and postinflammatory pigmentation.1. RAPK is an uncommon disorder, with approximately 130 reported ...
A Novel P53/POMC/Gas/SASH1 Autoregulatory Feedback Loop and Pathologic Hyperpigmentation. By Dingan Zhou, Jiawei Zeng, Xing Zeng, Yadong Li, Zhixiong Wu, Xin Wan, Pingshen Hu and Xiaodong Su. P53-regulated proteins in transcriptional level are associated with many signal transduction pathways and p53 plays a pivotal role in a number of positive and negative autoregulatory feedback loops. Although POMC/α-MSH productions induced by ultraviolet (UV) are directly mediated by p53, p53 is related to UV-independent pathological pigmentation. In the process of identifying the causative gene of dyschromatosis universalis hereditaria (DUH), three mutations encoding amino acid substitutions were found in the gene SAM and SH3 domain containing 1 (SASH1). SASH1 was identified to interact with guanine nucleotide-binding protein subunit-alpha isoforms short (Gαs). However, for about 90 years, the pathological gene and the pathological mechanism of DUH are unclear. Our study indicates that SASH1 is ...
Strategies for tackling rare diseases are also a priority of both the Community Action Programmes for Public Health and the Framework Programmes for Research and Technological Development. The three main objectives of the Second Community Action Programme for Public Health (2008-2013) are: (i) to improve citizens health security; (ii) to promote health, which involves reducing inequalities in this area; (iii) to generate and disseminate health information and knowledge. In particular, aim (ii) specifically mentions the promotion of action on rare diseases, where Community action by tackling their determinants can provide significant added value to national efforts. Within the first and second Community Action Programmes for public health, 32 projects on rare diseases have been funded to date, among which Orphanet is the best known European website dedicated to rare diseases and orphan drugs. Research on rare diseases is part of the objectives of the Framework Programmes for Research and ...
Alan Dowling consults and researches internationally on health strategy; health information exchange; EHR and PHR adoption; technology-based process innovation and reengineering; and information systems design, adoption and outcome measurement. In addition to his work as a Weatherhead affiliate instructor, he teaches graduate courses in health information systems as an adjunct professor at Case Western Reserve University. Dowling has published and lectured at leading institutions and conferences internationally on the adoption of health information technology, including EHRs and PHRs. He has over 35 years experience in health informatics having, as a U.S. Air Force officer, developed the conceptual design for a worldwide DoD EHR in 1975.. Dowling recently served on the federal Office of the National Coordinator - Health Information Technologys National Alliance Work Group on Defining Health Information Terms (EMR, EHR, and PRH). He was a member of the Clinton Administrations Healthcare Reform ...
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Dowling-Degos disease (DDD) is an autosomal dominant genodermatosis characterized by reticular pigmentation, usually in a flexural distribution. However, generalized DDD can also occur, with numerous hypopigmented or erythematous macules and papules on the neck, chest, and abdomen. The histopathology of DDD shows characteristic thin branch-like patterns of epidermal downgrowth (summary by Li et al., 2013). (615327) ...
article: A case of co-occurence of Dowling-Degos disease and psoriasis: association or a rarely-seen coincidence? - Giornale Italiano di Dermatologia e Venereologia 2018 December;153(6):884-5 - Minerva Medica - Journals
Dowling, S. and Albarran, J. (2017) Digital times: Disseminating your work and networking. British Journal of Cardiac Nursing, 12 (9). pp. 433-436. ISSN 2052-2207 Available from: http://eprints.uwe.ac.uk/33060 Dowling, S. and Albarran, J. (2017) Developing and producing a focused conference poster. British Journal of Cardiac Nursing, 12 (8). pp. 371-374. ISSN 2052-2207 Available from: http://eprints.uwe.ac.uk/32712 Albarran, J. and Dowling, S. (2017) Writing an effective conference abstract. British Journal of Cardiac Nursing, 12 (7). pp. 324-328. ISSN 1749-6403 Available from: http://eprints.uwe.ac.uk/32697 Albarran, J. and Dowling, S. (2017) Getting published a practical guide- Part II. British Journal of Cardiac Nursing, 12 (6). pp. 274-279. ISSN 1749-6403 Available from: http://eprints.uwe.ac.uk/32696 Albarran, J. and Dowling, S. (2017) Getting published: Part I. British Journal of Cardiac Nursing, 12 (5). pp. 228-231. ISSN 1749-6403 Available from: http://eprints.uwe.ac.uk/32695 Clompus, S. ...
Most of PeDRAs research takes place within one of five collaborative working groups - Birthmarks, Inflammatory Skin Disease, Genetic Skin Disorders, Neonatal Skin Care, and Skin Tumors and Reactions to Cancer Therapies (STARC). Each working group consists of dozens of clinician scientists, working under the guidance of one or more leaders to identify novel research ideas, advance our understanding of childhood skin diseases, and identify the best ways to improve the lives of patients and their families. PeDRA is able to leverage the strength of these working groups to identify and pursue cross-cutting studies that address high priority research questions spanning many different pediatric skin diseases. ...
Epidermolysis bullosa (EB) is a group of rare genetic skin disorders that primarily manifest as blisters and erosions following mild mechanical trauma. Despite the crucial role of the parents of children with EB in managing the disease, studies focusing on the parent-child relationship remain a gap in the literature. To address this gap, the current quantitative study, involving 55 children with all types of EB and 48 parents, assessed the relationship between their quality of life and coping strategies. Quality of life was measured with the Pediatric Quality of Life Inventory and TNO-AZL Questionnaire for Adults Health- related Quality of Life, and coping strategies were assessed with the Coping with a Disease Questionnaire. The majority of the analyses were descriptive and the results were interpreted qualitatively because of the small sample size. Overall, the quality of life of children with EB and that of their parents was somewhat lower compared with the quality of life of healthy children and
Ichthyosis is a family of genetic skin disorders characterized by dry, scaling skin that may be thickened or very thin. Ichthyosis affects people of all ages, races and gender. The disease usually presents at birth, or within the first year, and continues to affect the patient throughout their lifetime. What are some of the problems…
In treating this severe and very rare genetic skin disorder (harlequin ichthyosis) upon delivery, the babys airway and circulation is the foremost priority. The healthcare team must ensure that the babys/patients airway, breathing, and circulation are in stable condition after delivery. The baby will require intravenous access. It will be through the access where the medication will be given. Peripheral access may be difficult. Umbilical cannulation may be necessary. The infant must be placed in a humidified incubator, the temperature, respiratory rate, heart rate and oxygen saturation must be monitored by the healthcare team. Once the vital sign have stabilized the baby is then transferred into a level 3 neonatal nursery station or room ...
By: Zama Ngcoya. While albinism is regarded as simply a genetic disorder in the Western world, in African cultures some still believe it is a curse from the greater forces.. Hlobisile Masinga says that to her it is a genetic skin disorder that makes you lighter than average individuals.. Masinga (19) from Ematikwe, a small township at Inanda, was diagnosed with albinism when she was born. She had inherited the genetic disorder from her mother, who is also an albino.. She said that in her childhood, she had no understanding of the condition.. Growing up, all I knew was that the sun hurt my skin and that I had poor vision. No one actually understood me besides my mother, the only other albino in my family, who unfortunately died when I was eight years old, she said.. Masinga also says she was given special treatment due to the color of her skin.. I had people who wanted to shake my hand, give me money or pity me just because I was lighter in complexion. It was annoying at first but as I ...
I am dedicated to providing high quality and compassionate patient care. I enjoy interacting with families and treating all types of pediatric skin problems. My special focus is on hemangiomas and genetic skin disorders ...
Six-year-old, Rafi, a resident of Manhattan, suffers from a rare genetic skin disorder which causes her to have a very delicate skin that blisters and tears even with the slightest touch.
Indeed i believe alot of histologists would slip through the cracks in a histo-census. (if you wanted to count both research and clinical labs). I work in a research lab (Dermatology Dept)- and I am an histologist. I embed tissue in paraffin, i run immunohistochemistry experiments, etc... My official title is Electron Microscopy Technician. But, since i was hired on, my duties have shifted. Also, since Im a research technician that performs histological duties, am i considered an histologist? We occasionally do clinical work (diagnose genetic skin disorders), but mostly we are a research lab (investigating the mechanisms of wound healing.) Lara Lara Muffley Dermatology Dept University of Washington Seattle, WA [email protected] On Thu, 30 Aug 2001, Cheryl Crowder wrote: > Its an interesting subject - how many histotechs in the world. I think > one would never find the answer. I am a histotech - for over 30 years. > When I came to Louisiana, I was hired through State Civil ...
Oral Genodermatoses A concise manual of oral manifestations of genetic skin diseases. Dentistry LAP LAMBERT Academic Publishing (2016-04-12) - ISBN-13: 978-3-659-87167-2 ...
Epidermolysis bullosa (EB), is a rare, genetic skin disease that causes skin to blister and scrape off with the slightest friction or trauma. It affects the skin and lining of the mouth and oesophagus. Previously, there was no treatment and no chance for cure. In some countries, even euthanasia has been considered for newborns with the severest forms. If children with EB do not die of infection in their early life, many with the disease do not live beyond their 20s or 30s because they develop an aggressive form of skin cancer. While a few will live long term, the severest forms of EB are generally lethal ...
Epidermis regeneration is an important approach to helping patients with a variety of serious skin problems that can arise due to genetic conditions or injuries such as severe burns.. An exciting new Nature paper reports epidermis regeneration on a strikingly large-scale. The child who is the subject of the study suffers from a sometimes fatal genetic skin disease called junctional epidermolysis bullosa (JEB). In fact, in the particular case described in the new paper, the patient would have likely died without some transformative intervention given the severity of his JEB. Instead, after receiving a large combination transgenic skin graft, today he is doing well and has a largely normal epidermis. This encouraging outcome was reported in the paper by an international team (Italy and Germany) led by Michele De Luca entitled, Regeneration of the entire human epidermis using transgenic stem cells. Interestingly, this paper also points toward a central role for stem cells in epidermis ...
Ichthyosis is a broad term used to describe a family of rare, genetic skin diseases. The main characteristics of the diseases are dry, thickened and scaly skin, states...
Two new studies funded in part by NIHs National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) describe efforts to develop stem cell-based approaches for treating Epidermolysis Bullosa (EB), a rare, genetic skin disease. The findings, which were published jointly in the journal, Science Translational Medicine, may lead to individualized therapies for EB, and possibly other genetic diseases. People with EB have skin that is so fragile that the slightest friction causes blisters. The severity of the disease ranges from limited tearing of skin on the hands and feet to widespread blistering and scarring, including mucosal surfaces like ...
Two new studies funded in part by NIHs National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) describe efforts to develop stem cell-based approaches for treating Epidermolysis Bullosa (EB), a rare, genetic skin disease. The findings, which were published jointly in the journal, Science Translational Medicine, may lead to individualized therapies for EB, and possibly other genetic diseases. People with EB have skin that is so fragile that the slightest friction causes blisters. The severity of the disease ranges from limited tearing of skin on the hands and feet to widespread blistering and scarring, including mucosal surfaces like ...
Julie Dowling rolls her office chair from drawing table to bookcase and pulls an old leather-bound tome from the shelf. Its a Canadian missionary manual from 1884 used to assimilate the natives. She pats the volume and says: I de-colonise old stuff like this. I like working with borderline souvenirs, a kind of Australiana meets a viscous kind of colonialism. I swim in that and try to make friends with it. Then reaching into a folio she smiles as she brings out a shops delivery list dated 1951, and says: I found it on the verge. I like using ephemera like this.. Born in inner city Perth, Dowling grew up in the outer suburb of Redcliffe when it was mostly bushland. When one section of Redcliffe became a local dumping ground it had a major impact on Dowling. Shed go bush hunting with her nanna and theyd find old books, Bibles, health manuals and the like. Thats how I learned about art. It was a form of gathering information on the fringe, learning from it, knowing you have ...
We were in Newfoundland and the weather was awful - lots of wind and rain, she says. I had been passed up for the national team and, yeah, had a chip on my shoulder, which I enjoy having. I like being an underdog because it motivated me then and it motivates me now.. I felt like if I won the Canadian Amateur, they would take a look at me and when I won, they did just that, so I got to play in the World Am. Fighting the conditions as much as the course, Dowling still remembers trudging down the damp fairways in the stinging rain and pulling off several clutch shots to capture the title, calling it an experience of a lifetime.. She was no slouch in the classroom either, earning numerous academic awards to go with both the 2002 Women of the Year award and the Kent State Female Athlete of the Year award in her senior year.. Turning pro, Jan Dowling competed on the Futures (now Symetra) and Canadian Womens Tour, honing her game for the LPGA Tour. Unfortunately, earning LPGA Tour status proved ...
In simple terms your spleen becomes Kick your foot pain to the curb in these visibly high-tech orthopedic shoes . does chantix cause weight loss nausea and vomiting. Work hard and play harder - Hilux helps you do just that.. Department of Surgery Division of Transplantation and 2 Department of Internal Medicine Division of Nephrology University of Calgary Vitamin B Diabetes Mellitus No Hereditaria Foothills Medical Centre Shielding The Brain From Too Much Insulin Can FULL STORY. Patient education for preventing diabetic foot ulceration Johannes A N Dorresteijn 1 tion of St. Interview: Sonya Smith Diabetes Specialist Nurse. Every other diabetic eye problems treatment itch type 2 jock diabetes financial assistance/resource page that I would visit would give you a link The Medtronic Financial Assistance Program offers help to Cognitive dysfunction includes conditions ranging in seriousness from the relatively benign mild cognitive impairment (MCI) to dementia which can be extremely As with acute ...
Epidermolysis bullosa (EB) is a rare genetic skin disorder that causes extreme skin fragility, leading to recurrent blister formation with even minor trauma. There are three major forms of EB: EB simplex (EBS), Junctional EB (JEB), and Dystrophic EB (DEB). Each type of EB differs in severity and clinical presentation. Caring for all patients with EB requires a multidisciplinary approach.. ...
Kindler syndrome is a rare type of epidermolysis bullosa, which is a group of genetic conditions that cause the skin to be very fragile and to blister easily.From early infancy, people with Kindler syndrome have skin blistering, particularly on the backs of the hands and the tops of the feet. Explore symptoms, inheritance, genetics of this condition.
Contents: Cutaneous Anatomy, Biology and Inherited Disorders and General Dermatologic Concepts.- 1. Introduction and Historical Bibliography.- 2. Comparative Dermatology.- 3. Anatomy and Organization of Human Skin.- 4. Functions of the skin.- 5. Molecular Biology.- 6. Histopathology of the Skin: General Principles.- 7. Inflammation.- 8. Clinical Immunology, Allergy and Photoimmunology.- 9. Cutaneous Reactions.- 10. Wound healing.- 11. Diagnosis of Skin Disease.- 12. Dermoscopy.- 13. Trichoscopy.- 14. Reflectance Confocal Microscopy in Dermatology.- 15. Prenatal Diagnosis of Genetic Skin Disease.- 16. Evidence-Based Dermatology.- 17. Skin and Skin Disease throughout Life.- 18. Epidemiology of Skin Disease.- 19. Racial Influences on Skin Disease.- 20. Education in Dermatology.- 21. Genetics in Dermatology.- 22. Genodermatoses.- 23. Genetic Blistering Diseases.- 24. Naevi and other Developmental Defects.- 25. Disorders of Keratinization.- 26. Metabolic and Nutritional Disorders.- 27. The ...
Netherton syndrome (NS) is a severe genetic skin disorder, with often delayed or misleading clinical signs. The histological features of skin biopsies, usually described as a psoriasiform hyperplasia, have only been reported in isolated case reports or small case series. The aim of this study is to define, for the first time, the precise histological pattern of cutaneous lesions, in a large cohort of skin biopsies from confirmed NS patients. The study included 80 consecutive skin biopsies from 67 patients taken between January 1995 and June 2014. All were from confirmed NS patients with either a negative lympho-epithelial Kazal-type-related inhibitor (LEKTI) immunohistochemistry and/or molecular confirmation by identified mutation in SPINK5. In this cohort, the most frequent histological finding was also psoriasiform hyperplasia, but there were additional, less common, or previously unreported findings, including compact parakeratosis with large nuclei, subcorneum or intracorneum splitting, ...
Steve Dowling and Gordon Boshell were the originators of the Garth character. Dowling wanted to create a British adventure comic strip, and took inspiration from the American comic strips Superman,[2] Flash Gordon and Terry and the Pirates.[3] Dowling and Boshell took on 15-year-old John Allard to work on Garth, who stayed with the strip for its entire lifetime. After 59 adventures Dowling retired and handed Garth over to Allard, which he carried on until 1971 when Eagle comics Dan Dare artist, Frank Bellamy, took over the art with Allard writing the scripts.[1] Garths longevity had been established by Don Freeman, who created almost every basic Garth plot on which the saga was built. Peter ODonnell, Jim Edgar and Angus Allan also wrote extensively for the strip during its decades-long existence. Philip Harbottle is a leading Garth expert and collector of the strips, and he wrote several of the stories during the 1990s. Martin Asbury became Garths artist after Frank Bellamys death in 1976, ...
Citation Text: Birth year: -; Baptism year: 1842; Baptism date: 13 Feb 1842; Parish: Cappinrush; Alternative parish names: Ballyfin; Diocese: Kildare and Leighlin; County: Laois (Queens); Country: Ireland; Fathers first name(s): Dan; Fathers last name: Dowling; Mothers first name(s): Mary; Mothers last name: Hennehan ...
Gov. Mike DeWine has appointed the head of the GAR Foundation to replace Michael Dowling on the University of Akron board of trustees. Christine Amer Mayers term began Friday, Aug. 27, and will expire July 1, 2028. Mayer is president of the GAR Foundation, a local philanthropic group heavily involved in education and economic development. Christine Amer Mayer is a consummate professional that is known for her passionate support of organizations throughout the greater Akron area, and we look forward to having her join the Board of Trustees, board chairman Joseph Gingo said in a release. She will bring a truly unique perspective to the Board that will allow us to better serve the students at the University of Akron.. Mayer said she is humbled by the opportunity to serve on the board.. ...
Eddie Zakrzewski Staff Writer For most student-athletes, winning one championship is the ultimate goal or dream. But to be a part of three championships is something special. Colleen Dowling is a senior field hockey player for the Pioneers and has had the opportunity to be a part of the championships the field hockey team has...
Check Laura Viola Waugh Dowling and California: free people check with all available information for the name on the internet, Yasni.com Free People Search
Europa Universalis IV: Native Americans II Unit Pack contains new unique unit models for ten Native American tribes. Mikmaq Potawatomi Chickasaw Miami Navajo Mohican Assiniboine Ojibwe Fox ShoshonneThis DLC adds unique flavor to the North American continent and enhances the visual experience of Europa Universalis IV.
The empire building game Europa Universalis IV gives you control of a nation to guide through the years in order to create a dominant global empire. Rule your nation through the centuries, with unparalleled freedom, depth and historical accuracy.
The Universalis web site shows you today, yesterday, and the week ahead. It is free.. Links to all the available dates are on the right. (On small screens, the links may be shown below, on the left-hand side).. This is possible through the kindness of the various copyright owners who have allowed us to reproduce their texts here. The one-week limit is a compromise between giving you free access and giving them some reward for their hard work. Just like anyone else, translators have to eat.. If you want to see texts for more than a week ahead (or for the distant past), then you need to get one of our apps or programs.. We have apps for:. ...
The Universalis web site shows you today, yesterday, and the week ahead. It is free.. Links to all the available dates are on the right. (On small screens, the links may be shown below, on the left-hand side).. This is possible through the kindness of the various copyright owners who have allowed us to reproduce their texts here. The one-week limit is a compromise between giving you free access and giving them some reward for their hard work. Just like anyone else, translators have to eat.. If you want to see texts for more than a week ahead (or for the distant past), then you need to get one of our apps or programs.. We have apps for:. ...
A fun game is to scour through the patch notes for Paradoxs strategies, hunting for things that sound funny out of context. A good time can be had by all. Unfortunately, Ive not yet sat down to crack open Europa Universalis IV, so lack the necessary context to even parse this massive list of fixes. Event Conservative Backlash now requires idea divine_supremacy might sound funny, but what
EUROPA UNIVERSALIS IV: RIGHTS OF MAN DLC for PC is a digital code with no expiry date. Once bought, this downloadable code will be delivered directly to your email address with no shipping cost.
Existence of 64bit doesnt change the fact that Paradox players are known to be reluctant (or moneywise unable) to update hardware. If you can, try to remember the many complains at early CK2/EU4 release time when people complained on required shader type. I dont have the actual forum link but there is multiple confirmation on it, it may probably be in the tech subforum. I played yesterday EU4 at my friends house, we had no problem on his PC (it has EXACTLY 2 GB RAM, not less) till now, but he updated the game to 1.13, last weekend we still played on a version of 1.12(X/something) with no issues, and it is fairly strange that someone decided to ramp up the requirements as I seriously doubt that patch needed suddenly more RAM or 64bit to work when the previous one didnt. In any case, notifying wiki users of the change in minimum requirement should be of high priority, because not even Steam had it changed yet from 2Gb. For actual confirmation source maybe try contacting one of the 2 people ...
Expansion Europa Universalis IV Leviathan Mac Game Full Version Free In Direct Link To Play. Just Download The Game, Extract And Run
Dissertatio juris ecclesiastici universalis, de jure principis circa sacra libertati conscientiæ non inimico, quam ... auctor et præses, mag. Petrus Munck ... et respondens Johann. J. Holmén, Fierdhundrensis. In audit. Carol. Majori d. XV Junii, anni MDCCLIV. H. A. M. S. ...
Abiomed (Danvers, MA) has announced the introduction of a synchronized minimally invasive implantable cardiac assist device at the American Heart Association Scientific Sessions in Orlando, FL. Developed to treat patients with chronic moderate heart failure, the Symphony improves coronary perfusion and cardiac output. The device is the first implantable cardiac assist device designed for heart recovery or remodeling, according to Abiomed. According to the company, the system can be implanted in a patient in roughly 30 minutes. The pump is intended on being explanted after extended support at home.. Medgadget had the chance to talk to Robert Dowling, MD, who helped develop the device, to hear what he had to say about it.. Part of the beauty of the device is its simplicity, Dr Dowling told Medgadget. if I were talking to cardiologists about the device, I would say that we have a pump that we place with a minor operation. And I would say: You know where you put pacemakers? Thats where I put ...
Arches, specifically p.10 populations and methods.PDF here. [http://www.bact.wisc.edu/Microtextbook/modules.php?op=modload&name=Sections&file=index&req=viewarticle&artid=104&page=1 Microbiology Textbook. Copyright, Timothy Paustian© 1999-2004.] [1] Lary L. Barton Biotechnology handbooks. Vol. 8-Sulfate reducing bacteria. 1995 Plenum Press, New York. [2] Dowling, N.J., Widdel, F. and White, D.C. (1986) Comparison of the phospholipid ester-linked fatty acid biomarkers of acetate-oxidising sulphate-reducers and other sulphide-forming bacteria. J. Gen. Microbiol. 132,1815-1825. [3] Dowling, N.J., Nichols, P.D. and White, D.C. (1988)Phospholipid fatty acid and infra-red spectroscopic analysis of a sulfate-reducing consortium. FEMS Microbiol.Ecol. 53, 325-334. [4] Sulphate reducing bacteria-book) ...
Securing seed funding is a pivotal point in a tech startups lifecycle. Were thrilled to have won the trust and confidence of our investors and its very exciting to know we have the initial capital now to make our vision a reality says founder Andrew Dowling.. Our goal now is to build the first commercially viable version of the product, prove out the business model and validate the opportunity sufficiently for us to seek next-stage growth capital, Dowling said.. I think the cool thing about this business is not the fact they are creating a something that curates social media, that has been done many times to varying degrees, what I really like is the hardware associated with the product, a simple easy to navigate tablet specifically for their product. It means that their target market do not even need to navigate the interwebs to find the Tapestry website if they do not want to.. I do think however their sales targets are different to their user targets - and if they position this product ...
Shaw was married eight times: Jane Cairns (1932); Margaret Allen (1934-37); Lana Turner (1940); Betty Kern (1941-43), daughter of songwriter Jerome Kern; Ava Gardner (1945-46); Forever Amber author Kathleen Winsor (1946-48); Doris Dowling (1952-56) and Evelyn Keyes (1957-85). He had two sons by Kern and Dowling. In his later years, Shaw lived and wrote in the Newbury Park section of Thousand Oaks, California. Shaw had adult onset diabetes. In December 2004, he died due to the disease at age 94. ...
The Invaders are happy he did.. You got to have good players with character to make you want to coach, Invaders assistant coach Brent Lundgren said. It makes you want to prepare, do what you need to do, and work at it. Eric is the perfect example of that.. Dowling isnt a starter or a captain or even close to a leading tackler for the Invaders, but he doesnt need to be.. Im happy just doing whatever part I can to help the team out, Dowling said. Ive always been a motivated individual and football, whether Im at the top or the bottom, is very therapeutic for me just to have that release from normal everyday life and crack heads with these guys. Its been something thats always been there for me. Whether you win or lose, football always makes you feel a little bit better at the end of the day. ...
Greg Williamsons verbal wizardry is again on display in these funny and darkly serious poems. As Richard Wilbur said of his first collection, The Silent Partner, Williamson is concerned...with the fugitive nature of all orderings. And here, in the latest title in the Sewanee Writers Series, the doublings and hidden dangers in life and language ricochet wildly, as in the quadruple look at peoples relationship to nature and metaphor in The Dark Days or in the group of twenty-six Double Exposures where each poem has to be read three times.. ...
The groups had gathered on Lake Mohave, a translucent stretch of dammed-up Colorado River on the Arizona-Nevada border north of Laughlin, for the annual weeklong ritual of the Razorback Roundup. Each year for the past two decades, fish biologists from around the Southwest have traveled here to monitor the sucker population, hoping to save it from oblivion.. In coves up and down the lake, more than 40 scientists had trucked in enough provisions to fuel their long days and often soggy work. At Marshs camp, at the end of a long dirt road stretching west from Kingman, an elaborate kitchen was spread out around the base of a dead mesquite tree. Giant coolers held the ingredients for gourmet meals -- homemade pasta sauce, garlic bread, fresh-baked cookies -- and bottles of beer brewed by Tom Dowling, an ASU geneticist who studies the Mohave sucker populations diversity. Dowling had also packed a meat smoker for a midweek feast of pork and sweet potatoes.. The razorback sucker (Xyrauchen texanus), ...
Suffering is … Suffering is … Like a stone in a shoeOr grit in an oyster shellIt can become a blister orWith time and care a pearl On the other handIt can kill you. December 1995 in New Zealand. ...
WikiLeaks is at it again. They are dropping new information (unverified) on the web about the Engineering Development Group. Who are they? They are the CIA, specifically its elite hacking unit. Not too cool for national security potentially but good to know if you care about your digital privacy, or if you are an enemy of the state with something to hide. If you have never checked out the site, it is very interesting. The part that grabbed me was…. Keep Reading ...
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis s
OBJECTIVES/SPECIFIC AIMS: This study aims to examine the relative impact of aortic arch and carotid artery anatomy on the procedural times and clinical outcomes in patients who have suffered acute ischemic strokes (AIS). Mechanical thrombectomy remains the gold-standard of care for large vessel ischemic stroke. Given that short procedural times are necessary for good clinical outcomes, arterial access is an important technical consideration. It has been recently demonstrated that abnormal carotid artery anatomy can increase endovascular procedure times in this patient population. However, there are no studies examining the impact of aortic arch anatomy on operative times. Additionally, no studies have looked at the impact of aortic arch and carotid artery tortuosity on clinical outcomes in AIS. Thus, we sought to exam the influence of various aortic arch and carotid artery anatomic variables on interventional procedure times and clinical outcomes. METHODS/STUDY POPULATION: We included 56 ...
This contest aims at raising awareness about rare skin diseases and allowing people to express their feelings about this issue in a different (...). ...
La DMD es una enfermedad hereditaria, que afecta a cerca de uno en 3500 a uno en 6000 varones recién nacidos. La DMD causa debilidad muscular, que empeora con la edad. La debilidad muscular es generalizada y afecta el movimiento, el aparato