Fibroblast growth factor receptors (FGFRs) have been implicated in the malignant transformation and chemoresistance of epithelial ovarian cancer; however, the underlying molecular mechanisms are poorly understood. Increased sialyltransferase activity that enhances protein sialylation is an important post‑translational process promoting cancer progression and malignancy. In the present study, α2,6‑sialyltransferase (ST6Gal‑I) overexpression or knockdown cell lines were developed, and FGFR1 was examined to understand the effect of sialylation on migration and drug resistance, and the underlying mechanisms. It was identified that cells with ST6Gal‑I overexpression had increased cell viability and migratory ability upon serum deprivation. Moreover, ST6Gal‑I overexpression cells had strong resistance to paclitaxel, as demonstrated by low growth inhibition rate and cell apoptosis level. A mechanistic study showed that ST6Gal‑I overexpression induced high α2,6‑sialylation of FGFR1 and ...
Low-passage-number clinical influenza virus isolates often appear insensitive to NAI when tested in MDCK or other laboratory cell lines. This precludes the detection of changes in viral drug sensitivity (resistance) between pre- and posttreatment isolates and can give rise to false-positive identification of resistance in population screening. This study was undertaken to test whether a genetically engineered increase in the density of human influenza virus receptors on the surface of MDCK cells can make the virus more sensitive to NAI in these cells. To address this question, we permanently transfected MDCK cells with the gene of human 2,6-sialyltransferase.. Stable transfection with the SIAT1 gene increased the concentration of 6-linked sialic acids on the surface of MDCK cells about twofold. This effect is consistent with enhanced α-2,6-sialylation in several other mammalian cell lines after their transfection with SIAT1 (6, 10, 12, 24, 25). We found that a typical non-egg-adapted human H1N1 ...
Citation: Murdoch, B., Fu, A., Meng, Y., Li, C., Hansen, C., Snelling, W.M., Moore, S.S. 2004. Assignment of the SIAT4A gene to bovine chromosome 14 by linkage mapping of an associated microsatellite. Animal Genetics 35:146-147. Interpretive Summary: A new DNA marker for the Sialyltransferase 4A (SIAT4A) gene was developed and mapped. The marker was developed from the CHORI-240 bacterial artificial chromosome library. Cattle from an Angus-based commercial seedstock line, and two USDA-MARC reference families were genotyped. The USDA-MARC reference family genotypes were used to map the marker onto cattle chromosome 14. Technical Abstract: CHORI-240 bovine bacterial artificial chromosome library high density filters were probed with gene-specific overgo primers for Sialyltransferase 4A (SIAT4A). All positive clones were confirmed by polymerase chain reaction (PCR) with different gene-specific primers. Subsequently the clones were digested with Sau3 AI and subcloned into the E. coli cloning vector ...
ST3Gal V (or GM3 synthase) is the sialyltransferase that catalyses the initial step in the biosynthesis of most complex gangliosides from lactosylceramide. ST3Gal V plays a key regulatory role in determining the cell surface ganglioside profile and, consequently, in modulating a large variety of ganglioside-dependent cellular events, such as cell proliferation and differentiation, adhesion, apoptosis, oncogenesis. In addition, a homozygous loss-of-function mutation in the hST3Gal V gene is cause of an autosomal recessive infantile-onset symptomatic epilepsy syndrome. Recently, we have identified a hST3Gal V mRNA variant containing an additional translation start codon, located upstream and in-frame with that considered unique translation initiation site in the human GM3 synthase gene, providing the first evidence of the existence of two differentially N-terminal extended isoforms of the protein [1]. The functional relevance of the longer isoform has to be defined yet, and a study to define its ...
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Activation of an aberrant glycosylation pathway in cancer cells can lead to expression of the onco-foetal sialyl-Tn (sTn) antigen. STn is a truncated O-glycan containing a sialic acid α-2,6 linked to GalNAc α-O-Ser/Thr and is associated with an adverse outcome and poor prognosis in cancer patients. The biosynthesis of the sTn antigen has been linked to the expression of the sialytransferase ST6GalNAc1, and also to mutations in and loss of heterozygosity of the COSMC gene. sTn neo- or over-expression occurs in many types of epithelial cancer including gastric, colon, breast, lung, oesophageal, prostate and endometrial cancer. sTn is believed to be carried by a variety of glycoproteins and may influence protein function and be involved in tumour development. This review discusses how the role of sTn in cancer development and tumour cell invasiveness might be organ specific and occur through different mechanisms depending on each cancer type or subtype. As the sTn-antigen is expressed early in
Expression of ST6GALNAC2 (SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM) in oral mucosa tissue. Antibody staining with HPA048849 in immunohistochemistry.
Expression of ST6GALNAC2 (SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM) in esophagus tissue. Antibody staining with HPA048849 in immunohistochemistry.
TY - JOUR. T1 - Neuraminidase-dependent degradation of polysialic acid is required for the lamination of newly generated neurons. AU - Sajo, Mari. AU - Sugiyama, Hiroki. AU - Yamamoto, Hideaki. AU - Tanii, Takashi. AU - Matsuki, Norio. AU - Ikegaya, Yuji. AU - Koyama, Ryuta. PY - 2016/1/5. Y1 - 2016/1/5. N2 - Hippocampal granule cells (GCs) are generated throughout the lifetime and are properly incorporated into the innermost region of the granule cell layer (GCL). Hypotheses for the well-regulated lamination of newly generated GCs suggest that polysialic acid (PSA) is present on the GC surface to modulate GC-to-GC interactions, regulating the process of GC migration; however, direct evidence of this involvement is lacking. We show that PSA facilitates the migration of newly generated GCs and that the activity of N-acetyl-α-neuraminidase 1 (NEU1, sialidase 1) cleaves PSA from immature GCs, terminating their migration in the innermost GCL. Developing a migration assay of immature GCs in vitro, ...
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ST6Gal-I Restrains CD22-Dependent Antigen Receptor Endocytosis and Shp-1 Recruitment in Normal and Pathogenic Immune Signaling†: The ST6Gal-I sialyltransferase
Presentation of sialic acid (Sia) varies among different tissues and organs within each species, and between species. This diversity has biologically important consequences regarding the recognition of cells by xeno antibodies (Neu5Gc vs Neu5Ac). Sia also plays a central role in inflammation by influencing binding of the asialoglycoprotein receptor 1 (ASGR-1), Siglec-1 (Sialoadhesin), and cellular interactions mediated by the selectin, integrin, and galectin receptor families. This review will focus on what is known about basic Sia structure and function in association with xenotransplantation, how changes in sialylation may occur in this context (through desialylation or changes in sialyltransferases), and how this fundamental pathway modulates adhesive and cell activation pathways that appear to be particularly crucial to homeostasis and inflammation for xenografts ...
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein ,=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl- ...
Hailey later married and moved to New York, where she again found herself active in parish work. One of the priests there knew that I was trying to discern whether I should study for the ministry. He told me, You can run but you cannot hide from God if you are being called. So I entered a program and came to the realization that my heart just was not into becoming a priest and running a church, but I was very interested in working directly with people ...
The present invention provides improved methods for the preparation of sialyl galactosides. The methods use sialyl transferase cycle in which the reaction conditions are optimized to provide increased yields.
italiaDesign is an undergraduate field school and research program offered by the School of Interactive Arts + Technology (SIAT) at Simon Fraser University in Vancouver, Canada. italiaDesign is a sister program to ...
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Multiple phenotypic changes in mice after knockout of the B3gnt5 gene, encoding Lc3 synthase--a key enzyme in lacto-neolacto ganglioside synthesis.
Žmonės tampa vegetarais dėl įvairių priežasčių. Tam gali turėti įtakos vietinė religija ir kultūra. Žmogus gali tapti vegetaru ir dėl etinių sumetimų, nepateisinant, pvz., gyvūno naudojimo žmogaus reikmėms, šiuolaikinės maisto pramonės praktikų, kuomet gyvuliai yra dažnai užauginami nenatūraliomis sąlygomis ar metodais.[12][13] Tokie vegetarai pasisako už gyvūnų teises ir dažnai dalyvauja socialiniame aktyvizme. Dalis vegetarų tokią mitybą pasirenka dėl sveikatos priežasčių. Vegetarų kūno masė palyginus mažesnė, jų [4][5][6], cholesterolio kiekis ir kraujospūdis mažesnis, nei žmonių, valgančių tiek gyvūninį, tiek augalinį maistą. Vegetarai 20 procentų rečiau miršta nuo išeminės širdies ligos, palyginus su nevegetarais. Įvairūs tyrimai rodo, kad vegetarai gyvena nuo 1 iki 5 metų ilgiau už mėsėdžius[7]. Ilgesnę vegetarų gyvenimo trukmę gali lemti ir kiti faktoriai, ., aukštesnė socialinė - ekonominė padėtis arba retesni ...
Introdu o: A corre o da di stase dos m sculos retos do abdome realizada principalmente pela sua plicatura, procedimento que consome muito tempo cir rgico. O objetivo deste estudo avaliar a efic cia e o tempo necess rio para a corre o da di stase dos retos do abdome comparando a plicatura com sutura cont nua em plano nico plicatura em dois planos. M todo: Foram inclu das 20 mulheres com hist ria de pelo menos uma gesta o. Foram randomizadas em dois grupos, um submetido plicatura dos retos do abdome em dois planos (controle) e outro sutura em plano nico cont nuo (estudo) com mononylon 2-0. Mediu-se o tempo necess rio para a realiza o de cada uma das t cnicas. Para an lise estat stica, foram usados os testes n o param tricos de Mann-Whitney, Friedman e Wilcoxon, considerando estatisticamente significante p < 0,05. Todas as pacientes foram submetidas ultrassonografia previamente cirurgia, 3 semanas e 6 meses de p s-operat rio. Resultados: A plicatura do grupo estudo mostrou-se t o eficaz quanto do ...
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The aim of this work is to show a novel environment to simulate and calculate the forces exerted in each point of contact when grasping with power or precision. Virtual hand was designed and validated with 25 degrees of ...
Žmogaus organizmas - tai nuolatos dirbantis mechanizmas, kurio kiekviena detalė atlieka svarbų vaidmenį. Nors šioje sistemoje svarbiausi yra gyvybę palaikantys organai - širdis, plaučiai, smegenys, tačiau svarbu prisiminti, jog ir kitos organizmo struktūros privalo būti geros būklės tam, kad žmogus galėtų gyventi pilnavertį gyvenimą, pavyzdžiui, jo judesių nevaržytų skausmai. Todėl visi sutiksite su tuo, kad sąnariai yra labai svarbi organizmo struktūros dalis, be jų negalėtume ne tik sportuoti, bet ir atlikti kasdieninių judesių. Keli įdomūs faktai apie sąnarius:. ...
Žmogaus papildomos viruso (HPV) vakcinos - tai skiepai, apsaugantys nuo užsikrėtimo tam tikrų tipų žmogaus papilomos virusu (ŽPV).[1] Rinkoje esančios vakcinos gali apsaugoti nuo dviejų, keturių arba devynių genotipų ŽPV.[1][2] Visos vakcinos apsaugo bent nuo ŽPV 16 ir 18, kurie kelia didžiausią gimdos kaklelio vėžio pavojų. Manoma, kad vakcinos gali apsaugoti nuo 70 % gimdos kaklelio vėžio, 80 % išangės vėžio, 60 % makšties vėžio, 40 % vulvos vėžio atvejų ir galbūt nuo tam tikros rūšies burnos vėžio.[3][4][5] Vakcinos taip pat apsaugo nuo tam tikrų lyties organų karpų, šiuo atžvilgiu geresnę apsaugą teikia vakcinos prieš 4 ir 9 genotipų ŽPV.[1] ...
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Sintetiniai, nelaidūs orui, o jei dar ir kvepiantys kasdieniai įklotai, gali sukelti nepageidaujamą odos reakciją, išbalansuoti makšties pH ir sukelti makšties infekciją ar kandidozę.
Schede ed informazioni di natura ecologica su aspetti legati a specie erbacee ed animali e le loro funzioni e ruoli, sia di natura eco sistemica ...
The structurally similar polysialic acid capsules of group B meningococci and Escherichia coli K1 are poor immunogens, and attempts are currently being made to improve their immunogenicity by chemical modifications. An IgG monoclonal antibody to these polysialic acid capsules was used for the study of the presence of structurally similar components in tissue glycoproteins to investigate the reasons for the poor immunogenicity and to evaluate potential dangers in active or passive immunization. By immunoblotting polysialic acid was detected outside the brain in newborn rat kidney, heart, and muscle. It appeared in immunoblots as one component and with similar mobility to the neural cell adhesion molecule N-CAM. Specificity studies of the antibody and endosialidase treatment showed that the polysialic acid glycans detected were composed of chains as long as eight sialic acid residues or more. The polysialic acid was not detected in the corresponding tissues of the adult animal. These results ...
Psychiatric disorders are a group of human diseases that impair higher cognitive functions. Whole-genomic analyses have recently identified susceptibility genes for several psychiatric disorders, including schizophrenia. Among the genes reported to be involved in psychiatric disorders, a gene encoding a polysialyltransferase involved in the biosynthesis of polysialic acid (polySia or PSA) on cell surfaces has attracted attention for its potential role in emotion, learning, memory, circadian rhythm, and behaviors. PolySia is a unique polymer that spatio-temporally modifies neural cell adhesion molecule (NCAM) and is predominantly found in embryonic brains, although it persists in areas of the adult brain where neural plasticity, remodeling of neural connections, or neural generation is ongoing, such as the hippocampus, subventricular zone, thalamus, prefrontal cortex, and amygdala. PolySia is thought to be involved in the regulation of cell-cell interactions; however, recent evidence suggests that it is
111495PRTNeisseria meningitidis 1Met Leu Lys Lys Ile Lys Lys Ala Leu Phe Gln Pro Lys Lys Phe Phe1 5 10 15Gln Asp Ser Met Trp Leu Thr Thr Ser Pro Phe Tyr Leu Thr Pro Pro 20 25 30Arg Asn Asn Leu Phe Val Ile Ser Asn Leu Gly Gln Leu Asn Gln Val 35 40 45Gln Ser Leu Ile Lys Ile Gln Lys Leu Thr Asn Asn Leu Leu Val Ile 50 55 60Leu Tyr Thr Ser Lys Asn Leu Lys Met Pro Lys Leu Val His Gln Ser65 70 75 80Ala Asn Lys Asn Leu Phe Glu Ser Ile Tyr Leu Phe Glu Leu Pro Arg 85 90 95Ser Pro Asn Asn Ile Thr Pro Lys Lys Leu Leu Tyr Ile Tyr Arg Ser 100 105 110Tyr Lys Lys Ile Leu Asn Ile Ile Gln Pro Ala His Leu Tyr Met Leu 115 120 125Ser Phe Thr Gly His Tyr Ser Tyr Leu Ile Ser Ile Ala Lys Lys Lys 130 135 140Asn Ile Thr Thr His Leu Ile Asp Glu Gly Thr Gly Thr Tyr Ala Pro145 150 155 160Leu Leu Glu Ser Phe Ser Tyr His Pro Thr Lys Leu Glu Arg Tyr Leu 165 170 175Ile Gly Asn Asn Leu Asn Ile Lys Gly Tyr Ile Asp His Phe Asp Ile 180 185 190Leu His Val Pro Phe Pro Glu Tyr Ala Lys Lys Ile Phe Asn Ala Lys 195 200 205Lys Tyr Asn Arg ...
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TY - JOUR. T1 - In vitro biosynthesis of sialosylgalactosylceramide (G7) by mouse brain microsomes. AU - Yu, R. K.. AU - Lee, S. H.. N1 - Copyright: Copyright 2004 Elsevier B.V., All rights reserved.. PY - 1976. Y1 - 1976. N2 - A sialyltransferase activity which catalyzes the synthesis of sialosylgalactosylceramide (G7) from added galactocerebroside and CMP N acetylneuraminic acid has been demonstrated in mouse brain microsomes. The enzyme reactions shows a pH optimum of 6.3 and requires detergents. Both Mn2+ and Ca2+ inhibited the reaction, whereas Mg2+ had no effect. The apparent Km for galactocerebroside leading to G7 was estimated to be 8.7 x 10-4 M. The same microsomal preparation also synthesized hematoside when ceramide lactoside was the glycolipid acceptor. The apparent Km for ceramide lactoside was about 1/10th that for galactocerebroside. When the preparations were partially inactivated by heat the synthesis of G7 and of hematoside was reduced at approximately the same rate. Liver ...
Shop Polysialic acid transport protein ELISA Kit, Recombinant Protein and Polysialic acid transport protein Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
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Learn About Lysosomal Storage Disorders and How A Glycosyltransferase Activity Assay Can Be Used to Find Novel Therapeutics for These Diseases.
Rabbit monoclonal antibody raised against a human ST8SIA4 peptide using ARM Technology. A synthetic peptide of human ST8SIA4 is used for rabbit immunization.Customer or Abnova will decide on the preferred peptide sequence. (H00007903-K) - Products - Abnova
Bacterial adhesion is a crucial step in colonization of the skin. In this study, we investigated the differential adherence to human and pig corneocytes of six Staphylococcus aureus strains belonging to three human-associated [ST8 (CC8), ST22 (CC22) and ST36(CC30)] and two pig-associated [ST398 (CC398) and ST433(CC30)] clonal lineages, and their colonization potential in the pig host was assessed by in vivo competition experiments. Corneocytes were collected from 11 humans and 21 pigs using D-squame® adhesive discs, and bacterial adherence to corneocytes was quantified by a standardized light microscopy assay. A previously described porcine colonization model was used to assess the potential of the six strains to colonize the pig host. Three pregnant, S. aureus-free sows were inoculated intravaginally shortly before farrowing with different strain mixes [mix 1) human and porcine ST398; mix 2) human ST36 and porcine ST433; and mix 3) human ST8, ST22, ST36 and porcine ST398] and the ability of ...
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, ...
SPORTS/FOOTBALLOn the day before tommorow's qualifications game for qualification to the European Championship scheduled to take place at 20.15 at the Bežigrad stadium in Ljubljana, the Slovene selector Dr. Zdenko Verdenik is facing a load of problems. Zlatko Zahovič (Vitoria Guimares) has recently cancelled his participation in the team and participation of Marinko Galič and Matjaž Florjančič is still uncertain due to injury.
The Swedish governmental two year program Growing old, Living well was launched in 2010 with the specific intent to create innovation regarding housing for both able and frail older people. The program has been administered by the Swedish Institute for Assistive Technology (SIAT), which has diffused the allocation of 50 million Swedish crowns into various projects and studies about housing for the ageing generation. Sweden is entering the ageing country in which the group of people aged 65 years and above attains approximately 19 per cent. Apart from regular case studies on different phenomena that occur in relation to older people and housing, the Swedish government designated the architectural competition as an instrument for renewing contemporaneous thinking about ordinary and special housing for older people. National architecture competitions have been used to define space for dependent persons. These competitions have preceded reforms of the social act. In a parallel track, local ...
Take your performance to the next level with the MFactory PRO Series Gears. Recognizing the demand for transmission components that can withstand the extreme shock loads produced during Drag Racing, MFactory Competition Products are proud to offer our range of top-tier competition level gears. Final drive gears are cut
Geocaching is a treasure hunting game where you use a GPS to hide and seek containers with other participants in the activity. Geocaching.com is the listing service for geocaches around the world.
Valadares is a green parish, flanked by the beautiful dos Pozos, Alba and Galiñeiro mountains. Its almost 8 square miles are Vigos border with Val do Fragoso and Val Miñor. In the mountain of Galiñeiro, the best area for climbing in Vigo, theres an archaeological route on which you can see dozens of petroglyphs. Alba and Monte dos Pozos are the ideal place to enjoy Vigo with
Sporte l-tirozinas gali būti naudingas, kaip dopamino hormono aktivatorius smegenyse, kuris yra atsakingas už žmogaus aktyvumą bei motyvaciją. Vartojamas prieš-treniruotę gali veikti kaip energetikas.
Bozentano vartojimas kartu su takrolimuzu ar sirolimuzu tyrimų su žmonėmis metu neanalizuotas, tačiau gali didėti kartu su takrolimuzu ar sirolimuzu vartojamo bozentano koncentracija plazmoje (kaip ir bozentaną vartojant kartu su ciklosporinu A). Bozentanas gali sumažinti kartu vartojamų takrolimuzo ar sirolimuzo koncentraciją plazmoje. Todėl dėl šios priežasties bozentano vartoti kartu su ir takrolimuzu ar sirolimuzu nerekomenduojama. Pacientus, kuriuos gydyti tokiu vaistinių preparatų deriniu būtina, reikia atidžiai stebėti, ar neatsiranda su bozentanu susijusių nepageidaujamų reiškinių, be to, būtina stebėti takrolimuzo ar sirolimuzo koncentraciją kraujyje.. Šaltinis: Bosentan Norameda. Preparato charakteristikų santrauka. www.vvkt.lt. Sąveika su sildenafiliu. Sveikiems savanoriams 6 dienas vartojant po 125 mg bozentano du kartus per parą (nusistovėjus pastoviai jo koncentracijai plazmoje) kartu su sildenafiliu (po 80 mg tris kartus per parą) (nusistovėjus ...
vertical shaft impact crusher compare to impact crusher The Barmac B-Series Vertical Shaft Impact (VSI) crusher is the original rock-on-rock TRIOs vertical shaft impact crushers use high-speed rotor or
List of all the English words beginning with OE. œ, oe, OEF, OEL, OES., OES, oes, OEV, OECD, OEMs, oeno-, œno-, OEOB, oecus, oenin, Œnoë, Oenus, Œcles, œdema, Oekaki, Œneus, oenite, œstri, Oetaea, œthel, Œting, oeuvre, -oecious, œdemas, oedemas
Pa io aidimo tikslas labai paprastas: nueiti i ta ko A ta k B. Savaime ai ku, tas kelias bus pilnas kli i , kurias reik s veikti. Prad kime nuo vieno aid jo re imo. Beta versijoje yra lygi sekcija, apmokanti aisti. Taip pat yra atrakinamas mini lygis - aidimas, kuris man pasirod kvailokas. Tai ka kas pana aus okin jim per virvut , renkant ta kus. Kuo toliau, tuo okin ti reikia grei iau. Keliaujant per vairove pasi ymin ius lygius, taip aid iant galima u migt, jei neesi top lentel s fanas ir t b t netrok ti atsidurti, tarkim, top 15 s ra e. Taigi, apie lygius. Visi lygiai sudaryti i trij sluoksni Nors paprastai aid iant atrodo kad aidimas yra dvimatis, bet taip n ra. Kiekvienas objektas gali b ti pad tas skirtingame sluoksnyje ir nuo to priklausys ar j s beb gdamas nosimi sir it degant kub , ar praeisit pro al . Ta iau tai aid iant n ra sud tinga. Viskas i eina savaime, o ir okin jant laipteliais, jei jie yra skirtinguose sluoksniuose, per jimas tarp j vyksta automati kai. Lygi aplinkos n ra ...
Panaudotas branduolinis kuras ir kitos ilgaamžės didelio aktyvumo radioaktyviosios atliekos bus dedamos į geologinėje aplinkoje įrengtą atliekyną. Atsižvelgiant į atliekyno koncepciją, ten vyraujančias sąlygas, radioaktyviąsias medžiagas ir jų pakuočių tipus, išskiriami keli dujų susidarymo šaltiniai. Nustatyta, kad dėl plieninių radioaktyviųjų atliekų pakuočių ir metalinių konstrukcinių elementų korozijos susidarančios vandenilio dujos yra pagrindinis dujų šaltinis atliekyne, kuris gali kelti potencialią grėsmę ilgalaikei saugai.. Šiame projekte atlikti eksperimentiniai vandenilio dujų susidarymo tyrimai atliekyno sąlygomis, nustatyti vandenilio susidarymo greitį įtakojantys faktoriai, tirti susidariusių dujų sklaidos mechanizmai ir dėsningumai inžinierinėmis ir gamtinėmis medžiagomis bei vertinama susidariusių dujų įtaka ilgalaikei geologinių atliekynų saugai.. Projekto koordinatorius - Britų geologijos tarnyba (British Geological Survey ...
Ar kada pagalvojote, kad sudirgusi oda, tempimas ir skausmai per menstruacijas gali būti susiję su higienos priemonėmis?Makšties išskyros ir menstruacinis kraujas šiltoje, orui nelaidžioje aplinkoje greičiau irsta ir jau po 20 minučių pradeda dauginti
Kit Component:- KN223851G1, ST8SIA1 gRNA vector 1 in pCas-Guide vector- KN223851G2, ST8SIA1 gRNA vector 2 in pCas-Guide vector- KN223851D, donor…
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hey guys/gals i have been wanting to get a glock for ccw and for just playin around at the range im kinda stuck between the glock 23 and the baby 40...
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Greek | Latin: a suffix; actor, process, condition, or state of; result of; expresses a state or abnormal condition or process of some disease