Read Evolutionary implications of multiple SINE insertions in an intronic region from diverse mammals, Mammalian Genome on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

TY - JOUR. T1 - Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome. AU - Greally, John M.. PY - 2002/1/8. Y1 - 2002/1/8. N2 - To test whether regions undergoing genomic imprinting have unique genomic characteristics, imprinted and nonimprinted human loci were compared for nucleotide and retroelement composition. Maternally and paternally expressed subgroups of imprinted genes were found to differ in terms of guanine and cytosine, CpG, and retroelement content, indicating a segregation into distinct genomic compartments. Imprinted regions have been normally permissive to L1 long interspersed transposable element retroposition during mammalian evolution but universally and significantly lack short interspersed transposable elements (SINEs). The primate-specific Alu SINEs, as well as the more ancient mammalian-wide interspersed repeat SINEs, are found at significantly low densities in imprinted regions. The latter paleogenomic signature ...

It has been recognized that the Merle coat pattern in dogs is not only a visually interesting feature, but it also exerts an important biological role, in terms of hearing and vision impairments. In 2006, the Merle (M) locus was mapped to the SILV gene (aka PMEL) with a SINE element in it, and the inserted retroelement was proven causative to the Merle phenotype. Mapping of the M locus was a genetic breakthrough and many breeders started implementing SILV SINE testing in their breeding programs. Unfortunately, the situation turned out complicated as genotypes of Merle tested individuals did not always correspond to expected phenotypes, sometimes with undesired health consequences in the offspring. Two variants of SILV SINE, allelic to the wild type sequence, have been described so far-Mc and M. Here we report a significantly larger portfolio of existing Merle alleles (Mc, Mc+, Ma, Ma+, M, Mh) in Merle dogs, which are associated with unique coat color features and stratified health impairment ...

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Eukaryotic genomes harbour a number of mobile genetic elements (MGEs); moving from one genomic location to another, they are known to impact on the host genome. Short interspersed elements (SINEs) are well-represented, non-autonomous retroelements and they are likely the most diversified MGEs. In so …

Is SINE a valid Scrabble word? How many points in Scrabble is SINE worth? What does SINE mean? SINE how many points in Words With Friends?

whose Half, or soo43633 12, is therefore the Sine of 15, very nearly.. From whence the Sine of any inferior Arch may be found by bare Proportion. Thus, if the Sine of 1 be required, it will be, 15 : 1 :: ,oo43633 12 : ,ooo29.0888, the Sine of the Arch of one Minute, nearly. But if you would have the Sine of 1 more exaćtly determined (from which the Sines of other Arches may be derived with the same Degree of Exačtness); then let the Opperations, in p. 139, be continued to 11 Bise&tions, and a greater Number of Decimals be taken; by which Means you will get the Chord of zir; Part of the Semi-periphery to what Accuracy you please: Then, by proceeding as above (for finding the Sine of 15), the Sine of 1 Minute will also be obtained to a very great Degree of Exačtness.. ...

This program reads in sequences of real data values and prints their Fourier sine transforms (as computed by nag_fft_multiple_sine (c06hac)). It then calls nag_fft_multiple_sine (c06hac) again and prints the results which may be compared with the original sequence ...

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In Todays tutoring, we worked on Sine and Cosine laws, discussed why anyone would ever care about Trigonometry, SohCahToa and the like, and I waxed enthusiastic about how every basic trigonometric question is essentially a snapshot of the beautiful dynamics of rotation.. ...

To understand the more complex aspects of frequency and phase encoding of the MR image, it is necessary to review what happens when two sine waves are added together. If two sine waves have the same frequency but different phases, their summation is another sine wave with the same base frequency but a different amplitude and phase. When the two waves are perfectly in phase with each other, their signals augment each other. When they are slightly out of phase with each other, the overall signal is diminished, and they are said to destructively interfere. When the phase shift between them reaches 180°, the two waves exactly cancel each other ...

infile id resp cons age xero cosine sine female height stunted time age1 season time2 using xerop.dat list id time age xero cosine sine female height stunted in 1/20, clean id time resp age xero cosine sine female height stunted 1. 121013 1 0 31 0 -1 0 0 -3 0 2. 121013 2 0 34 0 0 -1 0 -3 0 3. 121013 3 0 37 0 1 0 0 -2 0 4. 121013 4 0 40 0 0 1 0 -2 0 5. 121013 5 1 43 0 -1 0 0 -2 0 6. 121013 6 0 46 0 0 -1 0 -3 0 7. 121113 1 0 -9 0 -1 0 1 2 0 8. 121113 2 0 -6 0 0 -1 1 0 0 9. 121113 3 0 -3 0 1 0 1 -1 0 10. 121113 4 0 0 0 0 1 1 -2 0 11. 121113 5 1 3 0 -1 0 1 -3 0 12. 121113 6 0 6 0 0 -1 1 -3 0 13. 121114 1 0 -26 0 -1 0 0 8 0 14. 121114 2 0 -23 0 0 -1 0 5 0 15. 121114 3 0 -20 0 1 0 0 3 0 16. 121114 4 1 -17 0 0 1 0 0 0 17. 121114 5 1 -14 0 -1 0 0 0 0 18. 121114 6 0 -11 0 0 -1 0 0 0 19. 121140 1 0 -19 0 -1 0 1 5 0 20. 121140 2 0 -16 1 0 -1 1 4 0 ...

The 5PB1206 is a high-performance TCXO / LVCMOS clock fanout buffer with individual OE pin for each output. The CLKIN pin can accept either a square wave (LVCMOS) or clipped sine wave (such as TCXO clipped sine wave output) as input ...

The 5PB1214 is a high-performance TCXO / LVCMOS clock fanout buffer with individual OE pin for each output. The CLKIN pin can accept either a square wave (LVCMOS) or clipped sine wave (such as TCXO clipped sine wave output) as input ...

Its easy to divide a sine wave (curve) into any number of slices so that area of all slices become equal. Its a problem of definite integral. Area...

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Short interspersed elements (SINEs) are ubiquitous components of eukaryotic genomes. SINEs are composite transposable elements that are mobilized by non-long terminal repeat (non-LTR) retrotransposons, also called long interspersed elements (LINEs). The 3′ part of SINEs usually originated from that of counterpart non-LTR retrotransposons. The 5′ part of SINEs mostly originated from small RNA genes. SINE1 is a group of SINEs whose 5′ part originated from 7SL RNA, and is represented by primate Alu and murine B1. Well-defined SINE1 has been found only from Euarchontoglires, a group of mammals, in contrast to the wide distribution of SINE2, which has a tRNA-derived sequence, from animals to plants to protists. Both Alu and B1 are mobilized by L1-type non-LTR retrotransposons, which are the only lineage of autonomous non-LTR retrotransposons active in these mammalian lineages. Here a new lineage of SINE1 is characterized from the seashore hagfish Eptatretus burgeri genome. This SINE1 family, designated

Short Interspersed Nuclear Elements (SINEs) are non-autonomous retrotransposons that comprise a large fraction of the human genome. SINEs are demethylated in human disease, but whether SINEs become transcriptionally induced and how the resulting transcripts may affect the expression of protein coding genes is unknown. Here, we show that downregulation of the mRNA of the tumor suppressor gene BRCA1 is associated with increased transcription of SINEs and production of sense and antisense SINE small RNAs. We find that BRCA1 mRNA is post-transcriptionally down-regulated in a Dicer and Drosha dependent manner and that expression of a SINE inverted repeat with sequence identity to a BRCA1 intron is sufficient for downregulation of BRCA1 mRNA. These observations suggest that transcriptional activation of SINEs could contribute to a novel mechanism of RNA mediated post-transcriptional silencing of human genes.

which is also a sine wave with a phase-shift of π/2 radians. Because of this head start, it is often said that the cosine function leads the sine function or the sine lags the cosine.. The human ear can recognize single sine waves as sounding clear because sine waves are representations of a single frequency with no harmonics.. To the human ear, a sound that is made of more than one sine wave will have perceptible harmonics; addition of different sine waves results in a different waveform and thus changes the timbre of the sound. Presence of higher harmonics in addition to the fundamental causes variation in the timbre, which is the reason why the same musical note (the same frequency) played on different instruments sounds different. On the other hand, if the sound contains aperiodic waves along with sine waves (which are periodic), then the sound will be perceived noisy as noise is characterized as being aperiodic or having a non-repetitive pattern.. ...

Personal zines do not share many of the characteristics of he texts that make up the bulk of sources studied in literary or cultural studies and, more specifically, scholarship on auto/biography. Of central importance to these non-traditional texts is the fact that sines are not mass-produced; they are not published by a professional publishing house, and thus not sanctioned as significant by [their] status as a mass produced commodity (Huff 510). Moreover, zines are not easily available, do not participate in standardised modes of presentation and distribution, and are not well recognised within literary communities or among the reading (most commonly constituted as book-buying) public. Zines are homemade, ephermeral and amateur. They circulate among communities of readers through the mail, in out-of-the-way spaces, and are passed around hand-to-hand among social groups. They are also non-traditional because of the modes of emplotment that characterise them; in the case of personal zines, ...

TY - JOUR. T1 - Evolutionary origins of retroposon lineages of Mhc class II Ab alleles. AU - Lu, Cheng-Chan. AU - Ye, Ying. AU - She, Jin Xiong. AU - Bonhomme, Francois. AU - Wakeland, Edward K.. PY - 1996/5/1. Y1 - 1996/5/1. N2 - Major histocompatibility complex (Mhc) class II Ab genes have evolved into three distinct lineages. While lineage 2 alleles differ from lineage 1 alleles by the insertion of a retroposon in intron 2, the basis for the extremely large intron 2 in lineage 3 alleles has heretofore been undetermined. In this report, we demonstrate by nucleotide sequencing that the genomic sequences of prototypic alleles from all three lineages diverge significantly and that lineage 3 is derived from lineage 2 by two insertional events in intron 2. One insert, composed of a member of B1 short interspersed repetitive elements (SINEs), occurs 508 base pairs (bp) 3 of exon 2, and the other, 1141 bp 3 of exon 2 within the retroposon that distinguishes lineage 2 from lineage 1. To assess the ...

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Presented is a circuit for the generation of low-frequency (0.001 Hz to 63 kHz) sine waves possessing stable amplitude and frequency characteristics using digital techniques. The circuit produces a 32-step approximation to a sine wave at a frequency

Dorsal spines (total): 3; Dorsal soft rays (total): 22; Anal soft rays: 19; Vertebrae: 18 - 19. This species is distinguished by its dark color; anal-fin rays 19, dorsal-fin rays 22; usually with a single, simple, pointed orbital cirrus; a simple, pointed barbel at the end of the maxilla; pointed teeth (Ref. 57933). ...

Another important property of a sine wave we need to be able to specify is its amplitude. In essence, the amplitude of a sine wave is its size. Unfortunately there are various ways of defining what is meant by the size of a sine wave, and you are likely to come across many of them in material you look at outside this unit. Before I explain what our definition is, it will help matters if we look at what is meant by the average value of a sine wave.. Figure 16 shows a sinusoidally a ...

In math, the sine of an angle is defined as the length of the side of a right triangle opposite the acute angle divided by the length of the hypotenuse. The lengths of these sides can be determined...

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Precalculus (6th Edition) Blitzer answers to Chapter 6 - Section 6.1 - The Law of Sines - Exercise Set - Page 720 27 including work step by step written by community members like you. Textbook Authors: Blitzer, Robert F., ISBN-10: 0-13446-914-3, ISBN-13: 978-0-13446-914-0, Publisher: Pearson

That is...sort of mind blowing..I never really though of triangles as part of a circle...and a circle part of a wave..How is this possible?? But this is only valid for triangles with angles from 0 to 90 degrees right? Also when I see sin, or cos, or tan, in an equation, they themselves dont inherently have any value right? they just denote an operation to do on another number? I was always thinking that sin, cos,tang, etc.. actually have a value associated with them..like pi ...

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Students (Kushal, Eddy, Johnny, Dev, Harish) at the MidSouth Computational Bioinformatics Conference, Kushal gets award, Stillwater, OK, 2014: http://news.tamuc.edu/computer-science-students-present-at-mcbios-conference ...

The sine is a beautifully smooth and curvy looking, simple and pure sounding waveform. It contains (it is!) just a single frequency (called the fundamental, and 100Hz in this example), and so has no harmonics in it. (multiples of the fundamental frequency) For LFOs, sine waves are very useful because they smoothly modulate, or pan, or filter, or... However, using only a few samples to represent the waveform isnt a good way to get the best fidelity. I have seen single cycle waveforms of sine waves that only have 37 samples. Which takes us neatly into why particular numbers of samples are used for single cycle waveforms.. There is a lot of variation in the numbers of samples that are used to represent a single cycle waveform. In Max (and MaxForLive), the ~cycle object originally defaulted to using 512 samples of a single cycle of a cosine wave. But it wasnt fixed - you could replace the default waveform by using any other set of 512 samples, or you could change the number of samples: more recent ...

A&E Dunamis pure sine wave inverter is the latest model presented by A&E Integrated Services Limited. The A&E Dunamis charger has achieved significant improvements on battery charging, AC transfer, etc. By adopting DIP (dual in-line package) switch, the A&E Dunamis pure sine wave inverter provides more smart options for users to customize the performance of the device.. Features of A&E Dunamis Pure Sine Wave Inverter, ...

Daniel Scher examines how the diversity of approaches to a computer-based assessment question can be gleamed from something as simple as the placement of three points on the graph of a parabola.

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When you finished reading part 1 of the introduction you might have wondered how to draw more than one line or curve into on plot. I will show you now.. To make it a bit more interesting we generate two functions: sine and cosine. We generate our x-values with numpys linspace function Continue reading Introduction to matplotlib - Part 2. ...

I sin afhandling redegør Jan Wålinder for sine undersøgelser af i alt 206 transvestitter og transseksuelle, som var kendt i litteraturen. (Han har altså ikke selv foretaget undersøgelser, interview eller andet af de pågældende, men alene undersøgt tilgængelig litteratur om dem). Beskrivelse af 43 ...

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iSmokeKing-produkter er beregnet for bruk av eksisterende røykere i alderen 18 år eller eldre som et alternativ til tobakksigaretter. Det skal ikke å brukes av barn. Vennligst rådfør deg med legen din før du bruker iSmokeKing-produkter hvis noe av det følgende gjelder for deg: hvis du er gravid, planlegger å bli gravid eller amme; hvis du har en medisinsk tilstand, ustabil hjerte tilstand, alvorlig hypertensjon eller diabetes; hvis du er allergisk / sensitiv for nikotin av noen av ingrediensene; hvis du er usikker på bruk / egnethet. Ikke bruk produkter om du er allergisk mot noen av ingrediensene. iSmokeKing sine produkter kan være helseskadelig og inneholde nikotin som er vanedannende. Hold iSmokeKing-produkter utenfor barns rekkevidde ...

John Abebe har vunnet fram i retten med sine milliardkrav mot Equinor i Nigeria. Nå blir «Mr. Statoil» selv beskyldt for falskneri og svindel med bevis.

Scientific American is part of Springer Nature, which owns or has commercial relations with thousands of scientific publications (many of them can be found at www.springernature.com/us). Scientific American maintains a strict policy of editorial independence in reporting developments in science to our readers ...

16. Tarsiers are prosimian primates of the genus Tarsius, a monotypic genus in the family Tarsiidae, which is itself the lone extant family within the infraorder Tarsiiformes. The phylogenetic position of extant tarsiers within the order Primates has been debated for much of the past century, and tarsiers have alternately been classified with strepsirrhine primates in the suborder Prosimii, or as the sister group to the simians (=Anthropoidea) in the infraorder Haplorrhini. Analysis of SINE insertions, a type of macromutation to the DNA, is argued to offer very persuasive evidence for the monophyly of Haplorrhini, where other lines of evidence, such as DNA sequence data, had remained ambiguous. Thus, some systematists argue that the debate is conclusively settled in favor of a monophyletic Haplorrhini.Tarsiers have enormous eyes and long feet. Their feet have extremely elongated tarsus bones, which is how they got their name. They are primarily insectivorous, and catch insects by jumping at ...

AB - BackgroundInactivation of one X chromosome is established early in female mammalian development and can be reversed in vivo and in vitro when pluripotency factors are re-expressed. The extent of reactivation along the inactive X chromosome (Xi) and the determinants of locus susceptibility are, however, poorly understood. Here we use cell fusion-mediated pluripotent reprograming to study human Xi reactivation and allele-specific single nucleotide polymorphisms (SNPs) to identify reactivated loci.ResultsWe show that a subset of human Xi genes is rapidly reactivated upon re-expression of the pluripotency network. These genes lie within the most evolutionary recent segments of the human X chromosome that are depleted of LINE1 and enriched for SINE elements, predicted to impair XIST spreading. Interestingly, this cadre of genes displays stochastic Xi expression in human fibroblasts ahead of reprograming. This stochastic variability is evident between clones, by RNA-sequencing, and at the ...

With the advent of new and improved high-throughput sequencing technologies in the last few years, a growing number of novel classes of small RNA, other than miRNAs or siRNA, has emerged, which appear as new actors in gene expression regulation. tRNA-derived small RNAs represent one of these novel members that are, surprisingly, among the most conserved class of small RNAs throughout evolution. They could represent the most primitive small RNA pathways from which the well-known canonical RNA silencing pathways reported in higher eukaryotes evolved. This review aims to make a compilation of the most relevant research literature in this field with the purpose of shedding light on the relation of these primitive tRNA-derived molecules with the gene silencing machinery.

A modified rice that borrows a gene from barley reduces its production emissions by starving paddy field microbes of the sugar they use to produce methane

الاكشن, والمغامرات لعبة الاكشن والمغامرات الرهيبة للاندرويد Android Sine Mora v1.27 |br| |br| Android Sine Mora v1.27 |br| &

window.onload = function() { var elements = document.getElementsByTagName(span); for (var i = 0; i < elements.length; i++) { var element = elements[i]; var id = element.getAttribute(rel) || ; if (id.length > 0) { element.onclick = function() { var oToShow = document.getElementById(this.getAttribute(rel)); if (oToShow) document.getElementById(HiddenTextContainer).innerHTML = oToShow.innerHTML; }; } }};function ShowHiddenText() { document.getElementById(HiddenTextContainer).style.display = block; document.getElementById(readlink).style.display = none;} Heres how to keep ants out of your plants-and pantry! Question. Hi Mike: Ants are just about ruining my lawn and garden with their mounds of sand. I can barely dig a hole for a new plant without digging into a nest. So far, I have been using boiling water, but this could take me forever -and Im not that young!

Amplitude refers to the size of a sine wave. It can be defined in various ways, but a standard definition is that it is the maximum value of a waves departure from its average value. (The average value of a sine wave lies midway between its peaks and troughs.) The size of a sine wave is sometimes also expressed as a peak-to-peak amplitude, which is the vertical distance from peak to trough.. Root-mean-square (r.m.s.) amplitude is a way of specifying the size of a sine wave so that compa ...

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The effect of varying the coefficients on a sine or cosine graph will be investigated in this GCSE Mathematics coursework. Updated graphics.

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Ans : (स) चल लौह उपयन्त्र आकर्षक तथा विकर्षण दो प्रकार के होते है। आकर्षण प्रकार के उपयन्त्र में एक स्थिर कुण्डली होती है। तथा एक अण्डाकार लोहे का टुकड़ा इस प्रकार कीलित रहता है कि वह कुण्डली को भीतर या बाहर घुमा सके। तथा विकर्षण प्रकार के उपयन्त्र में दो कच्चे लोहे के टुकड़ों को एक ही चुम्बकीय क्षेत्र में रखा जाता है। जिसमें से एक स्थिर लोह तथा दूसरा कीलित धुरी से जुड़ा होता है ...

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Krishna S, Yim DGr, Lakshmanan V, Tirumalai V, Koh JLy, Park JEun, Cheong JKong, Low JLeng, Lim MJs, Sze SKwan et al.. 2019. Dynamic expression of tRNA-derived small RNAs define cellular states.. EMBO Rep. 20(7):e47789. ...

Krishna S, Yim DGr, Lakshmanan V, Tirumalai V, Koh JLy, Park JEun, Cheong JKong, Low JLeng, Lim MJs, Sze SKwan et al.. 2019. Dynamic expression of tRNA-derived small RNAs define cellular states.. EMBO Rep. 20(7):e47789. ...

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Vurdering av hudens fuktighet med et Corneometer som hovedparameter, vurdering av barriere-funksjon med et Vapometer som sekundært parameter. Deltakerne vasket sine underarmer med såpe 2 timer før målingene ble utført. Utgangsmålinger ble gjort med intrumentene. Bio-Oil og en referanseolje ble deretter applisert på ulike steder på undersiden av underarmen hos alle deltakere. Det ble gjort nye målinger igjen umiddelbart etter applisering av produktet samt 2 timer senere, både før og etter at produktene ble tørket av. Et ubehandlet kontrollområde ble også målt samtidig ...

Vurdering av hudens fuktighet med et Corneometer som hovedparameter, vurdering av barriere-funksjon med et Vapometer som sekundært parameter. Deltakerne vasket sine underarmer med såpe 2 timer før målingene ble utført. Utgangsmålinger ble gjort med intrumentene. Bio-Oil og en referanseolje ble deretter applisert på ulike steder på undersiden av underarmen hos alle deltakere. Det ble gjort nye målinger igjen umiddelbart etter applisering av produktet samt 2 timer senere, både før og etter at produktene ble tørket av. Et ubehandlet kontrollområde ble også målt samtidig ...

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Hvordan kan vi bidra til at små bedrifter kan holde sine ansatte trygge, spesielt nå når covid-19 har skapt en helsekrise verden aldri tidligere har sett? Frankrike har nylig kommet opp med en tilskuddsordning som løser dette på en elegant måte.

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The MultiPlus, as the name suggests, is a combined inverter and charger in one elegant package. Its many features include a true sine wave inverter, …