Início The Effects of the Diterpenes Isolated from the Brazilian Brown Algae Dictyota pfaffii and Dictyota menstrualis against the Herpes Simplex Type-1 Replicative ...
By further chemical investigation of South China Sea gorgonian Menella kanisa, five new highly oxygenated guaiane lactones, menverins H-L (1-5, resp.), were obtained. Their structures were established by employing spectroscopic methods, computer modeling, and comparison of their data with those of related metabolites ...
Shunichi Hashimoto and co-workers from Hokkaido University have reported in Chemistry a European Journal on their total synthesis of englerin A. Chemistry - a European Journal paper
6. Picris nuristanica Bornmüller, Repert. Spec. Nov. Regni Veg. Beih. 108: 68. 1938. 新疆毛连菜 xin jiang mao lian cai Picris afghanica K. H. Rechinger & Köie; P. hieracioides Linnaeus var. indica Candolle; P. hieracioides subsp. nuristanica (Bornmüller) Kitamura; P. nuristanica var. indica (Candolle) Tzvelev; P. similis V. N. Vassiljev.. Herbs (10-)30-100 cm tall, annual or short-lived perennial. Stem erect, branched especially in apical portion, leafy; branches spreading-erect, ± densely covered with whitish 2-hooked hairs. Basal leaves narrowly oblong-elliptic to lanceolate, 8-12 × 1.5-2 cm, both surfaces with whitish rigid 2-hooked hairs, basally attenuate into a winged petiole-like portion, margin entire or sinuate-dentate, apex acuminate. Lower stem leaves sessile, otherwise similar to basal leaves; middle and upper stem leaves linear-lanceolate, margin ± entire. Synflorescence sparsely corymbiform, with few to some capitula. Involucre cylindric to narrowly campanulate, 1-1.5 ...
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The first total synthesis of the guaiane-type sesquiterpene, (+)-indicanone (1), isolated from the root of Wikstroemia indica, was accomplished based on the rhodium(i)-catalyzed Pauson-Khand-type reaction of the allenyne derivative, which was derived from (+)-limonene. This total synthesis unambiguously conf
Root extracts of Holostylis reniformis (Aristolochiaceae) yielded three new natural sesquiterpenes, a sesquiterpene with an unusual carbon skeleton, 4,5-seco-guaiane (7-epi-11-hydroxychabrolidione A, 1), a nine-membered lactone with new carbon skeleton (holostylactone, 2), and a new megastigmane [(6S,7E)-6,9-dihydroxy-10-(2-hydroxy-ethoxy)-4,7-megastigmadien-3-one, 3], together with bulnesol and sitosterol-3-O-β-D-glucopyranoside. The structures of these compounds were determined by spectroscopic analyses and B3LYP/STO-3G** theoretical studies.
This page contains information about Saussurea Lappa- Kuth, general information of the Saussurea Lappa or kuth , medicinal properties of Saussurea Lappa or kuth , curative and healing properties of Saussurea Lappa or kuth , use of Saussurea Lappa or kuth in Ayurvedic medicines, usefulness of Saussurea Lappa or kuth in the treatment of different diseases.
Two new guaiane-type sesquiterpenoids, valerol A (1) and kessyl 3-acetate (2), together with nine known compounds, valeracetate (3), anismol A (4), orientalol C (5), spatulenol (6), 4 alpha, 10 alpha-epoxyaromadendrane (7), (+)-8-hydroxypinoresinol (8), pinorespiol (9), pinoresinol 4-O-beta-D-glucopyranoside (10), and 8-hydroxypinoresinol 4-O-beta-D-glucopyranoside (11) were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1 and 2 were elucidated on the basis of spectroscopic methods (1D- and 2D-NMR, MS, UV, and IR). These compounds were evaluated for inhibitory activity on acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells ...
This thesis is concerned with a study of the external, environmental conditions on the growth and development of the carrot Daucus carota L., as well as the carotene content, morphogenetic and other effects of defoliation or extirpation of the apex. Auxanometer records of root growth in different environments were also obtained. Experiments have also been carried out to simulate environmental and other effects by means of external application of known plant growth substances, in an attempt to explain morphogenetic changes in terms of internal plant regulation. Briefly, the results of daylength/temperature experiments on tops and roots have indicated that maximum total plant growth results at relatively warm temperatures, but under these conditions the leaf fraction is favoured; lone-day treatment results in similar effects. Root and top temperatures had striking differential effects. Both can be simulated by gibberellic acid application which is not dependent on the site of treatment. At lower ...
Torilis japonica is a ANNUAL growing to 1 m (3ft 3in). It is in flower from Jul to August, and the seeds ripen from Aug to September. The flowers are hermaphrodite (have both male and female organs) and are pollinated by Insects, self.The plant is self-fertile. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils and prefers well-drained soil. Suitable pH: acid, neutral and basic (alkaline) soils. It can grow in semi-shade (light woodland) or no shade. It prefers dry or moist soil.
28. Saussurea conaensis (S. W. Liu) Fujikawa & H. Ohba, Makinoa. n.s., 8: 73. 2010. 错那雪兔子 cuo na xue tu zi Saussurea gossipiphora D. Don var. conaensis S. W. Liu, Acta Biol. Plateau Sin. 3: 71. 1984.. Herbs 12-20[-30] cm tall, perennial, monocarpic. Caudex unbranched. Stem solitary, ca. 1 cm in diam., erect, simple. Lower and middle stem leaves petiolate; leaf blade narrowly obovate or narrowly oblong, 5-10[-17] × [0.5-]1-2[-3] cm, both surfaces green and sparsely arachnoid but glabrescent, margin sinuate-dentate, apex obtuse to acute. Upper stem leaves linear, 2-5 × 0.5-1.5 cm, both surfaces purplish black and densely white lanate, margin entire, apex acute to acuminate. Capitulum solitary, on flat stem apex, sessile, hidden at anthesis by lanate indumentum. Involucre broadly campanulate, [1-]2-3[-6?] cm in diam. Phyllaries not seen. Receptacle without bristles or papillae. Corolla bright purple to purple, 7-12.5 mm, tube 2-5 mm, limb 5-7.5 mm. Achene cylindric, 3-5 mm, smooth, ...
Genus and Species: Dictyota sp. Optimal Medium: Alga-Gro® Seawater Optimal Temperature: 22° C Optimal Light: High (200 to 400 foot-candles) Motility: None Classification: Brown Algae
While Dictyota dichotoma has been cultured for decades, relatively little is known on the abiotic regulation of its growth, life cycle and release periodicity. Here, we evaluated the different abiotic
Havent seen a carrot look like this before; left in the ground from last year overwinter, its put on a lot of growth above ground this year and is now in flower ...
Whoogas are unique because they use the finest Merino sheepskin for their inner lining, making them a longer-lasting, more comfy boot than their ugglier-named competitor ...
Alas, our new apartment is too "new" to have come equipped with such lovely vintage accessories but one can still daydream... ...
Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.
N. Bogliotti, P. I. Dalko, J. Cossy Tetrahedron Lett. 2005, 46, 6915-6918.. [239] Regioselective synthesis of 1,2-and 1,3-diols from omega-hydroxy allyl acetates and carbonates via Pd complexes using boric acid and trialkyl borates. J. Cluzeau, P. Capdevielle, J. Cossy Tetrahedron Lett. 2005, 46, 6945-6948.. [238] Synthesis of polypropionate subunits from cyclopropanes. M. Defosseux, N. Blanchard, C. Meyer, J. Cossy Tetrahedron 2005, 61, 7632-7653.. [237] A short and enantioselective synthesis of colletodiol. L. Ferrie, P. Capdevielle, J. Cossy Synlett 2005, 1933-1935.. [236] Total synthesis of zincophorin. J. Cossy, C. Meyer, M. Defosseux, N. Blanchard Pure and Applied Chemistry 2005, 77, 1131-1137.. [235] Efficient enantioselective formal synthesis of Ro 67-8867, a NMDA 2B receptor antagonist. I. Dechamps, D. G. Pardo, P. Karoyan, J. Cossy Synlett 2005, 1170-1172.. [234] Palladium-catalyzed Suzuki-Miyaura coupling reactions involving beta,beta-dihaloenamides: Application to the synthesis of ...
J.S. Peterson. USDA NRCS National Plant Data Center (NPDC). United States, DC, Washington, USDA ARS National Arboretum. June 27, 2003. Usage Requirements.. ...
TY - THES. T1 - Total synthesis of cis-Hydroazulene sesquiterpenes : base-induced and -directed elimination and rearrangement reactions of perhydronaphthalene-1,4-diol monosulfonate esters. AU - Jenniskens, L.H.D.. N1 - WU thesis 1539 Proefschrift Wageningen. PY - 1992. Y1 - 1992. N2 - The total synthesis of a number of cis-fused hydroazulene sesquiterpenes is described in this thesis. In this synthetic study, ample attention is paid to the mechanistic aspects of the base- induced and -directed rearrangement and elimination reactions of perhydronaphthalene-1,4-diol monosulfonate esters. These reactions form the key steps in the synthetic routes that were followed.A general introduction into the chemistry of terpenes, with emphasis laid on the sesquiterpenes with a hydroazulene skeleton, is given in Chapter 1.In Chapter 2, an overview of the literature on the synthesis of these hydroazulene sesquiterpenes is presented. The different synthetic strategies towards the hydroazulene skeleton and their ...
Oncotarget | https://doi.org/10.18632/oncotarget.12962 Xuejing Lin, Zhangxiao Peng, Xiaohui Fu, Chunying Liu, Yang Xu, Weidan Ji, Jianhui Fan, Lei Chen, Lin Fang, Yao Huang, Changqing Su
Background aims. Cord blood is considered to be a superior source of hematopoietic stem and progenitor cells for transplantation, but clinical use is limited primarily because of the low numbers of cells harvested. Ex vivo expansion has the potential to provide a safe, effective means of increasing cell numbers. However, an absence of consensus regarding optimum expansion conditions prevents standard implementation. Many studies lack clinical applicability, or have failed to investigate the combinational effects of different parameters ...
MolluscaBase eds. (2020). MolluscaBase. Patella sagittata Gould, 1846. Accessed through: World Register of Marine Species at: http://www.marinespecies.org/aphia.php?p=taxdetails&id=738907 on 2020-06-05 ...
Violet and other dark coloured carrots (Daucus carota) are increasingly commercially viable again. They are often called heirloom carrots because the first cultivated carrots probably had purple roots. In fact, however, most violet varieties offered
M hre, Wilde Daucus carota - Price: 3,00 - Die wilde Möhre findet sich leider immer seltener an Straßenrändern. Dabei ist sie ein Elternteil unserer bekannten Kulturpflanze.
Care guide for Renal Cancer. Includes: possible causes, signs and symptoms, standard treatment options and means of care and support.
Cu o activitate de aproape 15 ani în Câmpina, căutăm mereu se ne îmbunătățim și să ne lărgim gamă de servicii medicale oferite, să oferim pacienților un mediu modern și sigur pentru desfășurarea actului medical.... Citește în continuare ...
Why the Stochastic Scientist? As Im sure you all know, stochastic is another word for random, which is what I intend for the focus of this blog. Although my formal training is as a molecular biologist, there are many other fields of science that are also fascinating and beautiful. Its my intention to blog about which ever scientific discovery or invention catches my, and hopefully your, fancy ...
New therapies for leukaemia are urgently needed. Carrots have been suggested as a potential treatment for leukaemia in traditional medicine and have previously been studied in other contexts as potential sources of anticancer agents. Indicating that carrots may contain bioactive compounds, which may show potential in leukaemia therapies. This study investigated the effects of five fractions from carrot juice extract (CJE) on human lymphoid leukaemia cell lines, together with five purified bioactive compounds found in Daucus carota L, including: three polyacetylenes (falcarinol, falcarindiol and falcarindiol-3-acetate) and two carotenoids (beta-carotene and lutein). Their effects on induction of apoptosis using Annexin V/PI and Caspase 3 activity assays analysed via flow cytometry and inhibition of cellular proliferation using Cell Titer Glo assay and cell cycle analysis were investigated. Treatment of all three lymphoid leukaemia cell lines with the fraction from carrot extracts which contained ...
Cholangiocarcinoma (CCA), the adenocarcinoma of the biliary duct, is commonly reported in Asia with the highest incidence in northeastern Thailand. Chemotherapy of this type of cancer is limited due to the lack of effective chemotherapeutic drugs. A series of previous studies support further research and development of Atractylodes lancea (Thunb) DC. (AL) as a potential candidate for the treatment of CCA as a crude ethanolic extract. In the present study, we aimed to develop an oral pharmaceutical formulation (capsule) of the standardized AL crude ethanolic extract for further clinical development in patients with CCA. Major steps included macroscopic and microscopic authentication of the AL rhizomes, preparation of standardized AL extract, preparation of oral pharmaceutical formulation (capsule) of the standardized AL extract, quantitative and qualitative analysis of the marker compound (atractylodin) in the formulated AL extract, evaluation of contaminations of heavy metals, pesticides ...
Through this work we followed the influence of some thermal treatments on the carotenoids content of carrots. Carrots were analyzed fresh and after blanching, boiling, freezing raw and freezing blanching prior. Carotenoids content of the samples was determined spectrophotometrically. As raw material were used carrots from the domestic market, Flam variety. The highest carotenoid content was recorded for raw carrot (82.716 mg / g). By boiling for 20 minutes, the content of carotenoids in carrot remains only 28% (23.209 mg /g). Frozen carrot also lose the contents of carotenoids, leaving only 33.8% (27.961 mg /g). The lowest content of carotenoids(20.196 g/g) was found in carrots blanched and then frozen for 2 months at -18˚C ...
The current study examined the attenuating influence of dietary carrot pomace powder (CaPP) on hypercholesterolemia and various oxidative stress-associated with biochemical parameters in hypercholesterolemic rats. Thirty two male albino rats weighing 110±10 g were divided into four groups, the first group received the basal diet only and served as (negative control), the second group received the hypercholesterolemic diet and served as positive control, the other groups received hypercholesterolemic diet supplemented with 10%, 20% CaPP for six weeks. The obtained results revealed that groups supplemented with 10% and 20% CaPP significantly decrease total lipid, total cholesterol, triglycerides, low density lipoprotein cholesterol, liver enzymes: alanine aminotransferase, aspartate aminotransferase compared to positive and negative groups. Organs weight, body weight gain significantly decreased compared with positive control. Moreover dietary carrot pomace powder can used to reduce the body ...
The diseased wood, agarwood, from the tropical tree taxa Aquilaria, is famed for its unique fragrance and medicinal values, mainly due to its richness in secondary metabolites such as the sesquiterpenes. The presence of sesquiterpenes in high numbers and amounts correlates with agarwood of high quality. To understand the synthesis of this important compound, we cloned two candidate genes in the terpenoid synthesis pathway from Aquilaria malaccensis Lam., a major agarwood tree species. The genes encoding sesquiterpene synthase (AmSesTPS1) and δ-guaiene synthase (AmGuaiS1) were successfully cloned from callus RNA, using specific primers derived from transcriptomic data, in a reverse transcription PCR reaction. The full-length complementary DNA (cDNA) sequence of AmSesTPS1 was 1632 bp encoding for 544 amino acids, and AmGuaiS1 was 1644 bp encoding for 547 amino acids. Sequence alignment analysis showed that AmSesTPS1 shared between 99 to 100 % identity with sesquiterpene synthase from Aquilaria sinensis
Feverfew (Tanacetum parthenium) - is a plant related to sunflowers and chrysanthemums. Feverfew leaves are irritating but once theyre purified, this plant has both soothing and anti-aging qualities:
Malignant mesothelioma (MM) is an uncommon neoplasm that arises from the cells lining the body cavities, in particular the pleural and peritoneal cavities. The treatment of MM is a major challenge with frustrating results for clinicians and patients alike. Despite the adoption of newly developed radiotherapic and chemotherapic regimens, the prognosis remains dismal and only modest improvements have been obtained thus far. In this scenario, a better comprehension of the molecular patterns is of paramount importance. Cyclooxygenases catalyze the rate limiting step in the production of prostanoids. Accumulating data demonstrate that overexpression of these enzymes, and in particular of cyclooxygenases- 2, promotes multiple events involved in tumorigenesis; in addition, numerous studies show that inhibition of cyclooxygenases- 2 can delay or prevent certain forms of cancer. Aim of this review is to discuss the current state of the art in mesothelioma, with a particular emphasis on the recent ...
Five new tremulane-type sesquiterpenes, 11,12-dihydroxy-1-tremulen-5-one (1), 11,12-epoxy-12 beta-hydroxy-1-tremulen-5-one (2), 5 alpha, 12-dihydroxy-1-tremulen-11-yl 2(S)-pyroglutamate (3), 2 alpha, 11-dihydroxy-1(10)-tremulen-5,12-olide (4), and 10 beta,11-dihydroxy-5,6-seco-1,6(13)-tremuladien-5,12-olide (5), as well as three new aliphatic diketones, 2,3-dihydroxydodecane-4,7-dione (9 and 10) and 1-hydroxydecane-2,5-dione (11), together with three known sesquiterpene analogues, tremulenediol A (6), conocenol B (7), and conocenolide A (8), were isolated from cultures of the basidiomycete Conocybe siliginea ...
Essential oil profiling in callus of some Daucus genotypes growing in Syria has been investigated in this work. Genotypes included three wild Daucus species (D. carota L, D. guttatus Sm. and D. bicolor Sm.) in addition to two carrot cultivars: red and yellow (D. carota L. subsp. sativus). Seeds were germinated in vitro and the roots of the resultant plantlets were used to initiate and grow callus ...
The yellow carrot 'Jaune du Doubs' (Daucus carota) originates from France from the region Doubs, which is where it got its name.
Going through photo archives this morning, I found this photo I took a number of years ago in Panama of a native bee landing on an Eperua falcata flower. Here is a previous post on Eperua falcata, the Bootlace Tree.
The field behind my yard was full of this last year and i had seedlings popping up all over the place. I was out there pulling some of them today and there are a lot of plants with roots a centimeter thick at the top and the few that i managed to pull out were 6 inches
Define Atractylodes lancea. Atractylodes lancea synonyms, Atractylodes lancea pronunciation, Atractylodes lancea translation, English dictionary definition of Atractylodes lancea. n. 1. Any of numerous often weedy plants of several genera of the composite family, including Cirsium, Carduus, and Onopordum, having prickly leaves and...
FEVERFEW: (Tanacetum parthenium or Pyrethrum parthenium or Chrysanthemum parthenium). Photographed in a wildflower garden in Beaver, PA, July 29, 2013.
Communications DOI: 10.1002/anie.201100706 Organocatalysis Cinchona Alkaloid Amide Catalyzed Enantioselective Formal [2+2] Cycloadditions of Allenoates and Imines: Synthesis of 2,4-Disubstituted Azetidines** Jean-Baptiste Denis, Graldine Masson,* Pascal Retailleau, and Jieping Zhu* Chiral azetidines[1] represent an important class of fourmembered nitrogen heterocycles that have a wide range of synthetic applications,[1-3] remarkable biological activities,[1, 4] and are prevalent in natural products.[1, 5] However, in contrast to the homologous small-ring saturated nitrogen heterocycles such as aziridines, pyrrolidines, and piperidines, the synthetic approaches to enantiomerically enriched azetidines are few in number and are generally multistep processes.[1, 6, 7] Among the different synthetic routes, the formal [2+2] cycloaddition[8] is certainly one of the most powerful methods for the construction of the strained four-membered ring. However, only a few catalytic enantioselective methods have ...
The composition of leaf cuticular neutral lipids of Amphoricarpos autariatus ssp. autariatus collected at canyon of river Tara (North Montenegro) was investigated by GC/MS (nonpolar fraction), LC-ESI TOF MS and 1H NMR spectroscopy (more polar fraction). The nonpolar fraction (ca. 15% of the whole surface extract) contained C27 - 33 n-alkanes, those with odd-number of carbons predominating. The LC-ESI MS and 1H NMR of the more polar fraction revealed 13 sesquiterpene lactones, constituting ca. 97.5% of the lactone mixture, identified as the known guaianolides, so-called amphoricarpolides, found previously in the aerial parts of the genus. The lactone fraction exhibited considerable in vitro effect against eight fungi, i.e. Aspergillus ochraceus, A. niger, A. versicolor, Penicillium funiculosum, P. ochrochloron, Trichoderma viride, Fusarium verticillioides and Fulvia fulvum ...
Daucus carota L.ssp.carota (wild carrot), an herb used in folk medicine worldwide, was recently demonstrated to exhibit anticancer activity. In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. Using the WST assay, the pentane fraction (F1) and 1:1 pentane:diethyl ether fraction (F2) were shown to possess the highest cytotoxicity against both cell lines. Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. Furthermore, treatment of MDA-MB-231 cells with either fraction significantly reduced the level of phosphorylated Erk but did
The genus Daucus includes about 20-25 species worldwide. Northern Africa represents a major center of diversity of Daucus, with Tunisia thought to contain 11 species and seven subspecies. The greatest
TY - JOUR. T1 - Repressed Ca2+ clearance in parthenolide-treated murine brain bEND.3 endothelial cells. AU - Tsai, Tien Yao. AU - Lou, Shyh Liang. AU - Cheng, Ka Shun. AU - Wong, Kar Lok. AU - Wang, Mei Ling. AU - Su, Tzu Hui. AU - Chan, Paul. AU - Leung, Yuk Man. PY - 2015/12/15. Y1 - 2015/12/15. N2 - Parthenolide is a sesquiterpene lactone compound isolated from the leaves and flowerheads of the plant feverfew (Tanacetum parthenium). The anticancer effects of parthenolide have been well studied and this lactone compound is currently under clinical trials. Parthenolide is also a protective agent in cardiac reperfusion injury via its inhibition of nuclear factor-κB (NF-κB). Not much is known if this compound affects signal transduction in non-tumor cells. We investigated whether parthenolide affected Ca2+ signaling in endothelial cells, key components in regulating the vascular tone. In this work using mouse cortical microvascular bEND.3 endothelial cells, we found that a 15-h treatment with ...
Medicago falcata Cold acclimation-specific protein: from alfalfa (Medicago falcata) cells; MW 17.6 kDa; expressed abundantly in cell-suspension cultures & is regulated at both the transcriptional & posttranscriptional levels; amino acid sequence given in first source
TY - JOUR. T1 - Melampodium leucanthum, a source of cytotoxic sesquiterpenes with antimitotic activities. AU - Robles, Andrew J.. AU - Peng, Jiangnan. AU - Hartley, Rachel M.. AU - Lee, Brigette. AU - Mooberry, Susan L.. PY - 2015/3/27. Y1 - 2015/3/27. N2 - A new tricyclic sesquiterpene, named meleucanthin (1), was isolated from an extract of the leaves and branches of Melampodium leucanthum, along with four known germacranolide sesquiterpene lactones, leucanthin-A (2), leucanthin-B (3), melampodin-A acetate (4), and 3α-hydroxyenhydrin (5). The chemical structure of 1 was elucidated by analysis of 1D and 2D NMR and mass spectrometric data. All compounds exhibited antiproliferative and cytotoxic efficacy against PC-3 and DU 145 prostate cancer cells, as well as HeLa cervical cancer cells, with IC50 values ranging from 0.18 to 9 μM. These compounds were effective in clonogenic assays and displayed high cellular persistence. They were also found to be capable of circumventing ...