We have developed a quantitative scintillation proximity assay (SPA) that reproduces the Raf/MEK/ERK signal transduction pathway. The components of this assay include human cRaf1, MEK1, and ERK2 and a biotinylated peptide substrate for ERK2. cRaf1 was expressed as a his-tagged protein in insect cell …

Development of plastic scintillation detector (PSD) systems for dosimetry has been evolving for two decades now. The subject area has been a topic of a keen research interest that has generated lot of publications lately. PSD systems are being introduced in the market place. Numerous PSD systems for External Beam Radiation Therapy and Brachytherapy have been proposed, most times differentiating from the original systems by slight changes in one or more components, such as the photodetector. However, few major technological and engineering innovations have enabled this new technology to be embraced by the community which helped launching these systems for commercialization (Standard Imaging, Radiadyne, etc.). Scintillation materials (plastic, scintillating fibers and liquid) have many properties that make them ideal for dosimetry including water equivalence and energy independence for MV photons, linearity with dose, dose rate independence, high spatial resolution and nanosecond fast response time.

The Tri-Carb 4910TR liquid scintillation counter provides the popular standard features needed for research applications and the versatility to expand for environmental analysis with the optional ultralow-level and alpha/beta discrimination features.. The Tri-Carb 4910TR liquid scintillation counter provides high performance and flexibility for multi-application and multi-user laboratories detecting radioactivity in life science research, environmental monitoring and/or health physics assays. Optional Packages are available for High Sensitivity Counting of low activity samples and Alpha Beta Separation for unknown or mixed samples.. Exclusive Standard Features. ...

SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...

SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...

SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...

SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...

SPA Imaging beads are microspheres containing scintillant which emit light in the red region of the visible spectrum. As a result, these beads are ideally suited to use with a CCD imager, such as PerkinElmerlj Viewlux™ CCD Imager.. Two types of core SPA Imaging bead are available - yttrium oxide (YOx) and Polystyrene (PS). A number of biological coatings also exist for each core bead type to enable receptor binding, enzyme, molecular interaction and radioimmunoassays to be investigated.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is ...

SPA Imaging beads are microspheres containing scintillant which emit light in the red region of the visible spectrum. As a result, these beads are ideally suited to use with a CCD imager, such as PerkinElmerlj Viewlux™ CCD Imager.. Two types of core SPA Imaging bead are available - yttrium oxide (YOx) and Polystyrene (PS). A number of biological coatings also exist for each core bead type to enable receptor binding, enzyme, molecular interaction and radioimmunoassays to be investigated.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is ...

Kinase inhibition. Flt-4 tyrosine kinase was obtained from ProQinase GmbH (Freiburg, Germany) and c-Kit tyrosine kinase from Upstate Biotechnology, Inc. (Lake Placid, NY). Each additional kinase used was generated as a cell lysate, following infection of insect cells with recombinant baculoviruses containing kinase domains. All enzyme assays were run at, or just below, the respective Km for ATP (0.2-30 μmol/L). The inhibitory activity of AZD2171 was determined against a range of recombinant tyrosine kinases [KDR, Flt-1, Flt-4, c-Kit, PDGFR-α, PDGFR-β, CSF-1R, Flt-3, FGFR1, Src, Abl, epidermal growth factor receptor (EGFR), ErbB2, Aur-A, and Aur-B] using ELISA methodology described previously ( 28). Selectivity versus CDK2 and CDK4 serine/threonine kinases was examined using scintillation proximity assays with a retinoblastoma substrate and [γ-33P]ATP ( 29). Activity versus the dual specificity kinase MAPK kinase (MEK), was determined with a MAPK substrate, [γ-33P]ATP, and paper ...

Levocabastine is an antiallergic drug acting as a histamine H1-receptor antagonist. In allergic conjunctivitis (AC), it may also antagonize up-regulation of the intercellular adhesion molecule-1 (ICAM-1) expressed on epithelial conjunctival cells. However, little is known about its effects on eosinophils, important effector cells in AC. The adhesion molecule integrin alpha(4)beta(1) is expressed in eosinophils; it interacts with the vascular cell adhesion molecule-1 (VCAM-1) and fibronectin (FN) in vascular endothelial cells and contributes to eosinophil activation and infiltration in AC. This study provides evidence that in a scintillation proximity assay levocabastine (IC(50) 406 microM), but not the first-generation antihistamine chlorpheniramine, displaced (125)I-FN binding to human integrin alpha(4)beta(1) and, in flow cytometry analysis, levocabastine antagonized the binding of a primary antibody to integrin alpha(4) expressed on the Jurkat cell surface. Levocabastine, but not ...

TY - JOUR. T1 - A new gadolinium-loaded liquid scintillator for reactor neutrino detection. AU - Ding, Yayun. AU - Zhang, Zhiyong. AU - Liu, Jinchang. AU - Wang, Zhimin. AU - Zhou, Pengju. AU - Zhao, Yuliang. N1 - Funding Information: This work was supported by Natural Science Foundation of China, National Basic Research Project of China, and Key Laboratory of Nuclear Analytical Techniques, Chinese Academy of Sciences. The authors thank Prof. Richard Hahn and Minfang Yeh, Brookhaven National Laboratory, and Prof. Igor Nemchenok, Joint Institute for Nuclear Research, for their valuable suggestions. All the people from Institute of High Energy Physics who gave help and supports for our experiments are gratefully acknowledged. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2008/1/1. Y1 - 2008/1/1. N2 - A high flash point, low toxicity gadolinium-loaded liquid scintillator (Gd-LS) has been developed for the detection of reactor neutrino. Carboxylic acid 3,5,5-trimethylhexanoic ...

div class=citation vocab=http://schema.org/,,i class=fa fa-external-link-square fa-fw,,/i, Data from ,span resource=http://link.libraries.ou.edu/portal/A-scintillation-counter-for-measurement-of-I131/gO1eaNur4-s/ typeof=Book http://bibfra.me/vocab/lite/Item,,span property=name http://bibfra.me/vocab/lite/label,,a href=http://link.libraries.ou.edu/portal/A-scintillation-counter-for-measurement-of-I131/gO1eaNur4-s/,A scintillation counter for measurement of I131 uptake in the thyroid gland, by William J. MacIntyre, (electronic resource),/a,,/span, - ,span property=potentialAction typeOf=OrganizeAction,,span property=agent typeof=LibrarySystem http://library.link/vocab/LibrarySystem resource=http://link.libraries.ou.edu/,,span property=name http://bibfra.me/vocab/lite/label,,a property=url href=http://link.libraries.ou.edu/,University of Oklahoma Libraries,/a,,/span,,/span,,/span,,/span,,/div ...

The second type of radiation detector we will discuss is called the scintillation detector. Scintillations are minute flashes of light which are produced by certain materials when they absorb radiation. These materials are variously called fluorescent materials, fluors, scintillators or phosphors.. If we had a radioactive source and a scintillator in the lab we could darken the room, move the scintillator close to the source and see the scintillations. These small flashes of light might be green or blue or some other colour depending on the scintillator. We could also count the number of flashes produced to gain an estimate of the radioactivity of the source, that is the more flashes of light seen the more radiation present.. The scintillation detector was possibly the first radiation detector discovered. You might have heard the story of the discovery of X-rays by Wilhelm Roentgen in 1895. He was working one evening in his laboratory in Wurzburg, Germany with a device which fired a beam of ...

0039] Hence, devices useful for dosimetry of a broad range of complex radiotherapy modalities, such as intensity-modulated proton therapy (IMPT) for proton therapy, using liquid scintillator detectors are provided herein. The systems presented herein may be useful for patient-specific quality assurance (QA), providing fast, accurate, and high-resolution dosimetry. These systems may provide real-time dosimetric information in both 2D planes and 3D volumes for radiation beams of either photons or protons. The radiation beam is interacting with the LS material to produce visible light. This light may be acquired in realtime with one or more high-sensitivity/high-speed CCD cameras. (As used herein, processing in near realtime or realtime generally refer to processing data without intentional delay, given the limitations of the system and the time required to accurately measure the data.) Processing these images in near realtime allow the characterization of the radiation beams. (As used ...

A digital neutron-γ imaging technique for mixed radiation field is described. The imaging system is based upon an organic liquid scintillator detector, a narrow tungsten collimator, fast digitiser and adjustable equatorial mount. Radioactive sources have been attached to a vertical plane and the digitiser has been used to digitise neutron and γ events. The digitised events have been discriminated using pulse gradient analysis and images have been generated of the count distribution in the source plane.. ...

It was the purpose of this experiment to examine the difference in the density determinations and, since the Geiger tube threshold is much lower, to calibrate the liquid scintillator so that it is capable to determining the absolute particle density with greater accuracy.

We have studied the calibration of PMTs in scintillation detectors, inducing single electron response on the PMT from primary scintillation produced by x-ray interaction. The results agree with those obtained by the commonly used single electron response (SER) method, which uses LED light pulses to induce the PMT SER. The use of the primary scintillation for PMT calibration will be convenient in situations where the PMT is already in situ, when it becomes difficult or even impossible to apply the SER method, e.g. in commercial sealed scintillator/PMT devices. Furthermore, we have experimentally investigated the possibility of fitting the high-charge tail of the PMT SER pulse-height distribution to an exponential function, inferring the PMT gain from the inverse of the exponent. The results of the exponential fit method agree with those obtained by the SER method for pulse-height distributions resulting from an average number of around 1.0 photoelectrons reaching the first dynode per ...

FlashPlate® is a white polystyrene microplate, designed for high-volume, homogeneous radiometric assays, based upon the principle of scintillation proximity. The interior of each well is permanently coated with a thin layer of polystyrene-based scintillant which provides a platform for non-separation assays using a variety of isotopes (e.g.,3H, 125I, 14C and 33P) without the addition of liquid scintillation cocktail. FlashPlate is available in both 96-well and 384-well formats.. ...

A radiation detector, in particular a gamma camera, is constructed and operated in such a fashion that only a predetermined number of light sensors (such as PMTs) adjoining each other in a cluster are used to generate a signal with amplitude and event position information. The camera may also use an array of individual scintillation elements (crystals) in place of a single crystal, with certain advantages obtained thereby. According to another aspect of the invention, there is a reflector sheet that defines an array of apertures through which scintillation light can pass from the scintillation crystal to a plurality of light sensors optically coupled to an optical window in an array corresponding to the array of apertures in the reflector.

Definition of scintillation camera in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is scintillation camera? Meaning of scintillation camera as a legal term. What does scintillation camera mean in law?

Tritium is usually measured by using a liquid scintillation counter. However, liquid scintillator used for measurement will become radioactive waste fluid. To solve this issue, we have developed a method of measuring tritium samples with plasma-treated plastic scintillator (PS)sheets (Plasma method). The radioactive sample is held between 2 PS sheets and the whole is enclosed in a a low-potassium glass vial. With the Plasma method of 2-min plasma treatment, we have obtained measurement efficiency of 48 ± 2 % for 2 min measurement of tritium except for tritiated water. The plasma treatment makes the PS surface rough and hydrophilic which contributes to improve the contact between tritium and PS. On the other hand, it needed almost 6 hours to obtain constant measurement efficiency. The reason was that the dry-up handling in the vial needed longer time to vaporize H{sub 2}O molecules than in the air. We tried putting silica gel beads into vials to remove H{sub 2}O molecules from PS sheet surface ...

Instruments. The HTS facility houses state-of-the-art liquid handlers and multi-mode plate readers that can be integrated into screening systems for automated HTS applications. The suite of plate readers contains instruments with varying sensitivities for all common modalities including absorbance, fluorescence, time-resolved fluorescence, fluorescence polarization and luminescence. Additionally, we offer label-free, alpha screen, scintillation proximity and high-content screening technologies. Liquid handling capabilities allow for volume transfers ranging from 2.5 nanoliters to liters, in various combinations of fixed and random plate arrays. Readers and liquid handlers are available for walk-up use, as well as automated screening. Furthermore, the facility staffs a full-time engineer to ensure the instrumentation meets or exceeds industry specifications for operation. Data Analysis and Storage. The informatics and statistical capabilities of the HTS facility include data storage, archival and ...

Scintillation fluids based on toluene or xylene will no longer be available except by special order. Principal investigators who are authorized to use radioactive materials or are applying for such use may petition the Executive Committee for a scintillation fluid exception. Petitions must be submitted in writing and clearly state why the use of a scintillation counting fluid with a flash point , 140o F is required for their scintillation counting needs ...

Read user reviews, compare products and contact manufacturers of Scintillation products, including particle counters, scintillation counters and radiometers on SelectScience.

Radioactivity Analysis. Blood and plasma samples (0.1 ml), urine samples (0.2 g), and cage rinses (0.5 g) were added to Ultima Gold XR scintillation cocktail. Feces were homogenized in water, and samples (0.2 g) were combusted using a Packard model 307 Sample Oxidizer (PerkinElmer Life and Analytical Sciences). Cage wipes were extracted in water using gentle shaking, and samples (0.5 g) were added to the scintillation fluid. The pooled mouse carcasses (3/sample) were cut into pieces and digested using 1 N NaOH, and samples (0.5 g) were weighed and decolorized using 30% H2O2. Ultima Gold XR scintillation cocktail was added, and the samples were counted after sitting overnight at room temperature. Each rat brain was homogenized using a probe-type homogenizer at a 1:1 ratio (w/w) with a solution of 36 μM tranylcypromine, an MAO inhibitor, before samples were combusted. All samplers were analyzed by LSC using Packard model 2900TR liquid scintillation counters.. Bioanalytical Analysis for Bicifadine ...

Dimitriadis, Alexis, Silvestre Patallob, I, Billas, I, Duane, S, Nisbet, Andrew and Clark, CH (2017) Characterisation of a plastic scintillation detector to be used in a multicentre stereotactic radiosurgery dosimetry audit ...

International Scholarly Research Notices is a peer-reviewed, Open Access journal covering a wide range of subjects in science, technology, and medicine. The journals Editorial Board as well as its Table of Contents are divided into 108 subject areas that are covered within the journals scope.

Liquid scintillation counting (LS Counting) is a laboratory-based technique that uses a Liquid Scintillation Counter (LSC) to count the radioactive emissions from a liquid sample. It is often used in the biological sciences to measure the uptake of radioactive isotopes into biological materials. The different forms of an element are called isotopes.. For instance, the nucleus of the element phosphorus has 15 protons but it may contain differing numbers of neutrons. If it has 13 neutrons it is called 28P (15 + 13 = 28) and if it has 19 neutrons it is called 34P. In fact phosphorus exists as 7 different isotopes:. 28P, 29P, 30P, 31P,32P, 33P, 34P. 31P is the most abundant form and is stable whereas the other isotopes may be unstable and emit radioactivity. In the case of 32P, a beta particle is emitted.. LSC is a method of counting radioactive emissions from a limited range of radionuclides. The common isotopes used include:. ...

Typically, a PET-scanner consists of a detector ring with 60 cm diameter and 20 cm length inside which the patient is positioned. For brain studies the patient bed is positioned in such a way that the entire brain is within the field of view. To investigate the entire patient the bed is moved step-by-step. The detector consists of scintillation detectors with scintillation crystals coupled to photomultipliers. The radiation, which is emitted from the patient after the injection of a weak radioactively labelled substance (radiotracer), causes light pulses within the scintillation crystals. This light is converted to electrical signals by the photomultiplier. A detector is linked to opposing detectors by a coincidence logic: if the radiation hits two opposing detectors within a time interval of, e.g. 6 ns, it is assumed that the radiation comes from a radiotracer molecule located on the line connecting the two detectors. During the PET study, which can last from a few minutes up to two or three ...

Scintillography is mainly used in scintillation cameras in experimental physics. For example, huge neutrino detection underground tanks filled with tetrachloroethylene are surrounded by arrays of photo detectors in order to capture the extremely rare event of a collision between the fluids atoms and a neutrino. Another extensive use of scintillography is in medical imaging techniques which use gamma ray detectors called gamma cameras. Detectors coated with materials which scintillate when subjected to gamma rays are scanned with optical photon detectors and scintillation counters. The subjects are injected with special radionuclides which irradiate in the gamma range inside the region of interest, such as the heart or the brain. A special type of gamma camera is the SPECT (Single Photon Emission Computed Tomography). Another medical scintillography technique, the Positron-emission tomography (PET), which uses the scintillations provoked by electron-positron annihilation phenomena. ...

BioAssay record AID 629721 submitted by ChEMBL: Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting.

The indoor 222Rn radionuclide was directly absorbed in typical 20 ml glass scintillation vials by passing −3 dm3of ambient air through 16 ml of water-immiscible non-volataile scintillation cocktail...

Functional interfaces play a vital role in biosensing, which requires proper allocation, orientation, conformation, activities and stability to achieve high affinity and stability of the biomolecules. However, the characterization [...]

A method was devised to measure gray and white matter cerebral blood flow simultaneously in multiple regions of the brain using 133Xenon and a multiple-crystal scintillation camera. Following magnification cerebral arteriography, 133Xe was injected into the internal carotid artery and the washout of tracer was monitored with a scintillation camera which consists of 294 individually collimated NaI (TI) crystals. These data, obtained from each crystal overlying the brain, were processed by a weighted least-squares nonlinear regression technique. The blood flow rates of the rapid and slow compartments were calculated by the Kety-Schmidt formula along with 95% confidence limits for each measurement.. In four patients, local increases or decreases in regional cerebral flow were correlated with areas of pathology. In one patient with a cerebral arteriovenous malformation, regions of local shunting of tracer were identified. Application of a three-compartment analysis to these curves permitted ...

Select the radioisotope Calcium Ca-45 Carbon C-14 Chrome Cr-51 Cobalt Co-57 Hydrogen H-3 Iodine I-125 Iodine I-131 Phosphorus P-32 Phosphorus P-33 Sodium Na-22 Sulfur S-35 ALI = Annual Limit of Intake EQ = Exemption Quantity For more information on other radioisotopes go to the Canadian Nuclear Safety Commission (CNSC) website. Ca-45 - Properties and Precautions Radiotoxicity Low to medium Half life 163 days Emission Moderate Energy Beta (0.257 MeV) Range in air 52 cm Critical organs/tissue Bone Precautions Gloves, Lab coat, Aerosol control, Contamination control Shielding 3 mm, plexiglas (lucite shield) Monitor beta-probe, wipes counted by liquid scintillation counter ALI 30 (ingestion) and 9 (inhalation) EQ 1 MBq TOP OF PAGE C-14 - Properties and Precautions Radiotoxicity Low to medium Half life 5730 years Emission Moderate Energy Beta (0.156 MeV) Range in air 24 cm Critical organs/tissue Fatty tissue Precautions Gloves, lab coat, aerosol control, contamination

환경시료중의 삼중수소준위를 조사하기 위하여, 국내 12개 지역에서 채취한 생물시료(쌀, 채소, 솔잎)중의 삼중수소를 분석하였다. 생물시료중의 삼중수소는 동결건조법과 건조시료의 연소법에 의해 조직자유수 삼중수소 (TFWT: Tissue-Free Water Tritium)와 조직결합수 삼중수소 (TBT: Tissue-bound tritium)로 분류 추출하였으며, 액 체 섬광계수기(Liquid Scintillation Counter)를 이용하여 각 시료중의 삼중수소를 측정하였다. TFWT 농도는 쌀의 경우 |TEX|$0.96{\sim}3.96Bq/l$|/TEX|, 배추는 |TEX|$0.83{\sim}3.40 Bq/l$|/TEX|, 솔잎의 경우는 |TEX|$1.02{\sim}3.01 Bq/l$|/TEX| 범위의 값을 나타내었으며, TBT/TFWT의 평균 농도비는 쌀의 경우 0.94,배추는 1.71, 솔잎은 1.39의 결과를 나타내었다. TBT/TFWT 농도비가 1보다 높은 이유는 TBT가 TFWT보다 식물체 내에서의 체류기 간이 길기 때문인 것으로 추측되며, TBT/TFWT의 농도비는

Receptor Binding Assay. Competitive binding assays were carried out to determine the binding affinities of opioid compounds for μ-, δ-, and κ-opioid receptors. Membrane protein (100 μg/tube) prepared from CHO-μ, -δ, or -κ cells was incubated in 50 mM Tris-HCl buffer (pH 7.4) containing 2 nM [3H]diprenorphine and different concentrations of compounds in a total volume of 0.5 ml for 30 min at 37°C. Nonspecific binding was determined with 50 μM naloxone. The binding was terminated by inserting the assay tubes into ice-cold water, and membrane-bound [3H]diprenorphine was rapidly separated by filtration through GF/C filters. The filters were washed with 5 ml of ice-cold Tris-HCl buffer three times, and filter-bound radioactivity was counted by a liquid scintillation counter.. [35S]GTPγS Binding Assay. [35S]GTPγS binding assay was used as a functional measure of the agonist efficacy and potency of these compounds for the μ-opioid receptor. Membrane protein (100 μg/tube) prepared from ...

BioAssay record AID 646449 submitted by ChEMBL: Displacement of [3H]-LSD from human full length cloned 5HT6 receptor expressed in human HEK293 cells by liquid scintillation counter.

Suitable for liquid scintillation counting, gamma counting and chromatography applications. Choose from a variety of vial, cap and liner materials. Scintillation vial materials include glass, HDPE and PP. Vials are available with caps attached or caps packaged separately.. ...

Beamlines on synchrotrons worldwide need a lot of specific components in order to carry out specialised and state of the art experiments. Scintillators are essential components which make X-rays visible so they can be detected with CCD or CMOS cameras.. The sub-micrometre resolution and high image contrast demanded by todays experiments require scintillator films with thicknesses in the range 1-20 μm as well as providing high optical quality and uniformity. Thin scintillators minimise degradations due to focusing defects, diffraction and spherical aberrations, therefore boosting the image contrast and spatial resolution. But the sophisticated techniques required to grow such crystals and their high specificity means that very thin single crystal film scintillators are not commercially available.. In April 2010, the ESRF established a unique liquid phase epitaxy facility for single crystal film scintillators. Liquid phase epitaxy is a technique whereby scintillating crystal layers are grown on ...

Marketech offers custom fabricated components and semi-finished stock from tungsten, refractory metals, ceramics, sapphire, heat sinks, crystals

Cardiac output was measured by the injection method, using I131-labeled human serum albumin as indicator, and measuring concentration-time curves through the intact skin with a collimated scintillation counter. Although, in principle, any number of blood vessels could be used as the measuring site, it was found that because of recirculation, ... read more suitable curves were obtained only if the counter was directed toward the head or the heart. Cardiac output values calculated from these curves were compared with values found with the classical sampling method. Head, heart, and arterial sampling curves were measured simultaneously with one injection of radioactive indicator. The measurements show that a head curve could be used in measuring cardiac output by the injection method, but it is not very successful because of the rather high standard deviation of the result (25 per cent). A heart curve, however, can successfully replace an arterial sampling curve. The accuracy of heart and arterial ...

Looking for online definition of Scintillation meter in the Medical Dictionary? Scintillation meter explanation free. What is Scintillation meter? Meaning of Scintillation meter medical term. What does Scintillation meter mean?

A method for producing a plastic scintillator is disclosed. A plurality of nano-sized particles and one or more dopants can be combined with a plastic material for the formation of a plastic scintillator thereof. The nano-sized particles, the dopant and the plastic material can be combined within the dry inert atmosphere of an extruder to produce a reaction that results in the formation of a plastic scintillator thereof and the deposition of energy within the plastic scintillator, such that the plastic scintillator produces light signifying the detection of a radiative element. The nano-sized particles can be treated with an inert gas prior to processing the nano-sized particles, the dopant and the plastic material utilizing the extruder. The plastic scintillator can be a neutron-sensitive scintillator, x-ray sensitive scintillator and/or a scintillator for the detection of minimum ionizing particles ...

BGO Arrays, Bismuth germanate Bi4Ge3O12 (BGO) is one of the most widely used heavy oxide scintillator materials. BGO has a high atomic number (83) of the heavy component Bismuth element and a high density of the material (7.13 g/cm3). The luminescence spe

Fluid reservoirs on either side of the tissue were filled with bicarbonate buffered mock cerebrospinal fluid; oxygen (95%) and carbon dioxide (5%) were bubbled vigorously through the mock cerebrospinal fluid to maintain normal pH level and to provide mixing. After allowing 30 min for equilibration to 37 [degree sign]C, the study drug was added to the epidural side of the meninges. For this experiment, unlabelled morphine sulfate (0.1-mg base) and x [micro sign]Ci14C-labeled morphine sulfate (specific activity = 82 x 103[micro sign]Ci/mg; New England Nuclear, Boston, MA) were added to the donor reservoir at t = 0. Thereafter at 5-min intervals, 100-[micro sign]l samples were removed from donor and recipient reservoirs and placed in liquid scintillation vials for subsequent determination of morphine concentration. Decays/min were counted in a Packard TriCarb 2000 liquid scintillation counter (Packard Instruments, Downers Grove, IL; uncertainty of measurement 4% for 2,500 total counts). At the end ...

Adams, T. A. (1979) The characteristics of a national digital topographic database. Masters thesis, Durham University.. Adams, Timothy A. (1979) Characteristics of a national topographic digital database. Masters thesis, Durham University.. Addinall, P. (1979) The understanding of nature in the Old Testament: an investigation of some scholarly views. Masters thesis, Durham University.. Al-Dargazelli, Shetha Selman (1979) The development of gas scintillation counters for high count rate x-ray detection. Doctoral thesis, Durham University.. Al-Din, Nadia Yussef Gamal (1979) Selection for university education in egypt:: practice, philosophy and perspective. Doctoral thesis, Durham University.. Al-Imam, Fatima Muhammad Nejib (1979) Abdallah ibn Umar Ibn Al-Khattab. Masters thesis, Durham University.. Alexander, K. I. (1979) Studies in plant competition. Masters thesis, Durham University.. Andrew, J. (1979) The administration of Durham County: a comparative assessment 1830 to 1895. Masters thesis, ...

Long Chain Polyunsaturated Fatty Acids (LCPUFA) are physiologically important precursors for eicosanoids, leukotrienes, and prostanoids. Desaturation of essential fatty acids (EFAs) by []6-desaturase is considered the rate-limiting step in conversion of EFAs to LCPUFA. This study was designed to study the conversion of EFAs by []6-desaturase in dog liver microsomes. Microsomes were prepared using fresh liver from healthy dogs. Microsomes were incubated with ¹⁴C labeled 18 carbon EFA substrates. Following incubation, lipids were extracted, saponified and phenacylated. The resulting fatty acid phenacyl esters (FAPES) were separated by HPLC. Radioactivity was measured with a liquid scintillation counter, converted to enzymatic activity, and expressed as pmol/min/mg protein. Using 18:3n-3 as substrate, the apparent []6-desaturase maximal velocity was 50.9 pmol/min/mg protein and using 18:2n-6 substrate, the maximal velocity was 5.4 pmol/min/mg protein. Apparent K[] values were 20.8 []M for ...

Early buyers will receive 10% customization on reports.. By scintillation material, the inorganic scintillators market is categorized into Sodium Iodide (NaI), Cesium Iodide (CsI), Lutetium Oxyorthosilicate (LSO) and Lutetium-yttrium Oxyorthosilicate (LYSO), Bismuth Germanate Oxide (BGO), Others [Barium Fluoride (BaF2), Lead Tungstate (PbWO4), Cadmium Tungstate (CdWO4), Cerium Bromide (CeBr3), Lanthanum Bromide (LaBr3), and Gadolinium Orthosilicate (GSO)]. The sodium iodide (NaI) segment is expected to command the largest share of the global inorganic scintillators market, by scintillation material in 2016. This is attributed to factors such as rising application horizon of sodium iodide, rise in homeland security expenditure to combat terrorism worldwide, and increasing number of nuclear power plants. However, the lutetium oxyorthosilicate (LSO) & lutetium-yttrium oxyorthosilicate (LYSO) segment is expected to grow at the highest CAGR during the forecast period. This is mainly due to its ...

The equipment used in gamma spectroscopy includes an energy-sensitive radiation detector, electronics to process detector signals produced by the detector, such as a pulse sorter (i.e., multichannel analyzer), and associated amplifiers and data readout devices to generate, display, and store the spectrum. Other components, such as rate meters and peak position stabilizers, may also be included.. The most common detectors include sodium iodide (NaI) scintillation counters and high-purity germanium detectors.. Gamma spectroscopy detectors are passive materials that wait for a gamma interaction to occur in the detector volume. The most important interaction mechanisms are the photoelectric effect, the Compton effect, and pair production. The photoelectric effect is preferred, as it absorbs all of the energy of the incident gamma ray. Full energy absorption is also possible when a series of these interaction mechanisms take place within the detector volume. When a gamma ray undergoes a Compton ...

In this thesis, we measured the activity of Alpha, Beta particles and Gamma Radiation in soil in the middle of Gaza Strip in general form by using five types of detectors. These detectors are:SolidStateNuclear Track Detectors (CR-39), Geiger Counter, Gamma Spectrometer, Scintillation counter and Portable Electra Plus. The middle region of Gaza Strip divided into four areas, in our survey, included Dier El Balah (D), Mughazi (M), Buriej (B) and Nusairat (N). From each area we have obtained ten of samples, each sample taken at the depth of one meter from the earth surface, the subsurface sample weight equal one kilogram. We removed the stones and roots from the samples, after that, the sample was placed in plastic bags, each sample was divided into two parts, each part was placed in a cup and CR-39 fixed on the lower surface of the cover of cup. The distance between the surface of the soil and CR-39 is very small, we put all of the samples in the saving place. The exposure time for the detectors ...

Our lab is equipped with a Rigaku Ultima IV x-ray diffractometer with a copper x-ray source and a scintillation counter detector. The Ultima IV, with Rigakus patented Cross Beam Optics (CBO), is a flexible, multi-purpose XRD. It incorporates fully automatic alignment and allows for fast, easy switching between focusing and parallel beam geometries without the need to reconfigure the system. Other features of the Ultima IV at Memorial University are the automatic 10-position sample changer with spinner and the high temperature (1500oC) attachment.. ...

Research laboratories specializing in lipid, protein, growth, and food microbiology abattoir and contain the following equipment: Gas chromatograph, scintillation counter, centrifuges, microfuges, gel electrophoresis apparatus for protein, DU-20 spectrophotometer, sterile hood and incubator, water baths, pH meters, freeze dryers, vacuum pumps, refrigerators, mixer homogenizers, slab dryer, fluorescence spectrophotometer, calorimeter, balances, and tissumizers.. The Department of Animal Science maintains a 1700 square feet reproductive biology laboratory with three small (300 square feet) adjacent laboratories equipped for cell culture, histology, and sample extraction and preparation. The cell culture room is equipped with a laminar-flow hood and a CO2 incubator (Flow Labs #1500). In addition, equipment necessary for modern molecular biology procedures has been provided.. ...

Intermediate For dyes, in manufacture of anthraquinone, in production of plastics & fibers, diluent for wood preservatives, scintillation counter crystals, organic semiconductor research, occurs in coal tar, smoked food (Merck 1989). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.. ...

Compound. Enantiomerically pure ABT-888 was synthesized by Abbott Cancer Research and Process Chemistry. The synthesis and cell-based evaluation will be published elsewhere (27).. In vitro PARP and SIRT assays. PARP assays were conducted in a buffer containing 50 mmol/L Tris (pH 8.0), 1 mmol/L DTT, 1.5 μmol/L [3H]NAD+ (1.6 μCi/mmol), 200 nmol/L biotinylated histone H1, 200 nmol/L slDNA, and 1 nmol/L PARP-1 or 4 nmol/L PARP-2 enzyme. Reactions were terminated with 1.5 mmol/L benzamide, transferred to streptavidin Flash plates (Perkin-Elmer), and counted using a TopCount microplate scintillation counter.. Nicotinamide [2,5′,8-3H]adenine dinucleotide and streptavidin SPA beads were purchased from Amersham Biosciences. Recombinant human PARP purified from Escherichia coli and 6-Biotin-17-NAD+ were purchased from Trevigen. NAD+, histone, aminobenzamide, 3-aminobenzamide, and calf thymus DNA (dcDNA) were from Sigma. Stem loop oligonucleotide (slDNA) ...

Article Laser gas detector systems for greenhouse gas emissions monitoring. Two types of portable laser based gas detector for measuring emissions of the greenhouse gases carbon dioxide (CO2) and methane (CH4) from oil and gas operations are describe...

TY - JOUR. T1 - Neutrino phenomenology of very low-energy seesaw scenarios. AU - De Gouvêa, André. AU - Jenkins, James. AU - Vasudevan, Nirmala. PY - 2007/1/29. Y1 - 2007/1/29. N2 - The standard model augmented by the presence of gauge-singlet right-handed neutrinos proves to be an ideal scenario for accommodating nonzero neutrino masses. Among the new parameters of this new standard model are right-handed neutrino Majorana masses M. Theoretical prejudice points to M much larger than the electroweak symmetry breaking scale, but it has recently been emphasized that all M values are technically natural and should be explored. Indeed, M around 1-10eV can accommodate an elegant oscillation solution to the liquid scintillator neutrino detector (LSND) anomaly, while other M values lead to several observable consequences. We consider the phenomenology of low-energy (M 1keV) seesaw scenarios. By exploring such a framework with three right-handed neutrinos, we can consistently fit all oscillation ...

The low energy gas scintillation proportional counter (LE-GSPC) is an imaging x-ray spectrometer. It is one of the narrow field instruments on board the SAX satellite and covers the lower energy range from 0.1 to 10 keV. The low energy response of the detector is achieved by using a driftless gas cell and a thin multilayer polyimide foil as entrance window. The overall design of the imaging GSPC for space application is described. Using unit level and system level calibration data, acquired at a synchrotron and a long beam x-ray source, the capabilities both in terms of energy and position resolution are discussed. The overall efficiency of the instrument which includes the mirrors effective area, the entrance windows transparencies, the detectors efficiency and electronics deadtime are reviewed. Background rejection issues and the experiments consequent sensitivity to the measurement of cosmic x- ray source spectra are addressed ...

S. OKeeffe, D. McCarthy, P. Woulfe, J. Cronin, and E. Lewis, Optical Fibre Based Scintillation Probe for Radiotherapy Dosimetry, in Imaging and Applied Optics Technical Papers, OSA Technical Digest (online) (Optical Society of America, 2012), paper AM3A.3 ...

Guanazole and aphidicolin were chosen as candidates in the search for a selective, non-genotoxic inhibitor of DNA replication which could be used instead of hydroxyurea to measure DNA repair synthesis in rat hepatocyte primary cultures by liquid scintillation counting. The genotoxicity of these 3 chemicals was studied using the Salmonella/liver homogenate assay and the autoradiographic UDS test in hepatocytes. Hydroxyurea was positive in both of these assays. Guanazole and aphidicolin did not induce DNA repair in hepatocytes. Aphidicolin was not mutagenic for Salmonella typhimurium, whereas guanazole increased the revertant numbers of strain TA102 slightly. The incorporation of [3H]thymidine was measured by liquid scintillation to determine DNA repair induced by 2-acetylaminofluorene (2-AAF), aflatoxin B1, benzo[a]pyrene, cyclophosphamide, H2O2, 6-hydroxydopamine, N-methyl-N-nitro-N-nitrosoguanidine (MNNG), methylnitrosourea (MNU), 4-nitroquinoline-N-oxide and UV irradiation in the presence of ...

This proposal is to develop a novel slide based proximity assay platform to quantify protein phosphorylation on tissues. The novelty of this assay platform is derived from the use of the quantum dot with two emission peaks for fluorescence resonance energy transfer (FRET): one emission as internal standard and the other as FRET donor. Change of ratio of the two emission intensity during the FRET c .... ...

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The study will assess the diagnostic efficacy (sensitivity and specificity) of Flurpiridaz F18 Injection MPI against SPECT MPI in patients screened for CAD as determined by ICA. Six hundred and eighty evaluable patients will be enrolled and will undergo SPECT MPI and Flurpiridaz F18 PET MPI. Patients will be considered for enrollment if they are scheduled to undergo or have undergone prior ICA without intervention (being either positive or negative for CAD ...

From August 2014 until August 2015, IORT was considered in 124 patients; 82 patients actually underwent IORT and were enrolled in the phase 2 study. Among the 42 patients who did not undergo IORT, the reasons of IORT cancellation were either preoperative decisions in multidisciplinary conference, including presence of a huge primary mass or multicentric tumor nodules (n = 4); neoadjuvant chemotherapy (n = 3); definitive axillary, supraclavicular, or internal mammary lymph node metastasis (n = 3); and tumor close to the skin (n = 9); and intraoperative decisions including persistent positive resection margins (n = 9), conversion to total mastectomy (n = 8), and shape of tumor cavity unsuitable for IORT (n = 6). Among the 82 patients treated with IORT, 55 patients who underwent a minimum follow-up period of 1 month after WBI were included in the analysis. Follow-up after IORT ranged from 12.7 weeks to 50.3 weeks with a median follow-up of 25.9 weeks. The median patient age was 52 years (range, 32 ...

TY - JOUR. T1 - Effects of Nitrogen and Oxygen contamination in liquid Argon. AU - Acciarri, R.. AU - Antonello, M.. AU - Baibussinov, B.. AU - Baldo-Ceolin, M.. AU - Benetti, P.. AU - Calaprice, F.. AU - Calligarich, E.. AU - Cambiaghi, M.. AU - Canci, N.. AU - Carbonara, F.. AU - Cavanna, F.. AU - Centro, S.. AU - Cocco, A. G.. AU - Di Pompeo, F.. AU - Fiorillo, G.. AU - Galbiati, C.. AU - Gallo, V.. AU - Grandi, L.. AU - Meng, G.. AU - Modena, I.. AU - Montanari, C.. AU - Palamara, O.. AU - Pandola, L.. AU - Pietropaolo, F.. AU - Raselli, G. L.. AU - Roncadelli, M.. AU - Rossella, M.. AU - Rubbia, C.. AU - Segreto, E.. AU - Szelc, A. M.. AU - Tortorici, F.. AU - Ventura, S.. AU - Vignoli, C.. PY - 2009/12/15. Y1 - 2009/12/15. N2 - Two dedicated and distinct tests of Nitrogen and Oxygen contamination effects in liquid Argon (LAr) have been performed within the WArP R&D program. Purpose of the tests is to detect the reduction of the LAr scintillation light emission as a function of the ...

This is a website created for the deposition of scientific-related administrative data of the Department of Environmental Science of the University of Puerto Rico, Río Piedras Campus.. Web Developement and database design by Eda C. Meléndez-Colom, Luquillo LTER Information Manager. Contact her for questions about this website. ...

The next probe from NASA from the New Frontiers program can return the first samples of matter from the comet Churyumov-Gerasimenko or try to find traces of

TY - JOUR. T1 - Activation cross sections of deuteron induced reactions on silver in the 33-50 MeV energy range. AU - Ditrói, F.. AU - Tárkányi, F.. AU - Takács, S.. AU - Hermanne, A.. AU - Ignatyuk, A. V.. PY - 2017/2/1. Y1 - 2017/2/1. N2 - Excitation functions were measured for the natAg(d,x)105,104Cd, 110 m,108m,106m,105g,104gAg and 101Pd, 105,101mRh reactions over the energy range 33-50 MeV by using the stacked foil activation technique and subsequent high-resolution gamma-spectrometry. We present the first experimental cross section data above 40 MeV for all of these reactions and the first experimental cross section data for natAg(d,x)108m,104gAg and 105,103Rh. The experimental data are compared with results of the model calculations performed with the ALICE-D, EMPIRE-D theoretical nuclear reaction model codes and with the TALYS code results as available in the TENDL-2014 and -2015 on-line libraries.. AB - Excitation functions were measured for the natAg(d,x)105,104Cd, 110 ...

This is a high resolution, analytical Scanning Electron Microscope that can reach 2.5nm resolution at an accelerating voltage of 30kV. The electron source is a LaB6 gun. It has a brighter source than the tungsten hairpin gun. Bright, high quality images can be obtained at all kV ranges from 1-30kV. It has a wide magnification range to observe a variety of samples from 10cm in diameter to nano-structures at very high magnification. This instrument is an ideal analytical system as it has an Oxford 50mm2 X-Max SDD x-ray detector attached that enables simultaneous imaging and elemental analysis at high count rates with 125eV energy resolution. It has also has an integrated Oxford/HKL EBSD detector for crystallographic analysis with nanoscale resolution.. Book this instrument. Find training for this instrument. ...

OUTCOME: The overall incidence of AEs (ie, AEs occurring from the time the informed consent is signed until the 2-week telephone follow-up [14-17 days post-flurpiridaz F 18 injection administration]) and treatment-emergent adverse events (TEAEs) (ie, AEs occurring at the time of flurpiridaz F 18 rest dose administration until the 14-17 day telephone follow-up) and the proportion of patients who discontinue because of an AE or TEAE are the primary safety outcome measures ...

0049] The ring buffer 15d receives an input of the reading signal 15r and outputs the event data 15k to a subsequent data processing stage 15i according to the reading signal 15r. The event data 15k in this situation is event data 15k of which the amount that is read is regulated according to the reading signal 15r. In other words, during the high count rate period, the ring buffer 15d outputs only the pieces of event data 15k stored in the buffer areas 1 to i, according to the reading signal 15r. On the contrary, during the normal period, the ring buffer 15d outputs the pieces of event data 15k stored in all of the buffer areas 1 to n, according to the reading signal 15r. As explained here, the event data 15k output from the ring buffer 15d is the event data 15k of which the amount that is read is regulated according to the reading signal 15r. The timing with which the ring buffer 15d outputs the event data 15k corresponds to, for example, the time at which the event data 15k has been stored ...

Gamage, K A A*; Joyce, M J*; Taylor, G C (2012) A comparison of collimator geometries for imaging mixed radiation fields with fast liquid organic scintillators. IEEE Trans. Nucl. Sci., 59 (4). pp. 1432-1437. Full text not available from this repository ...

Improved Scintillators for Time-of-Flight Positron Emission Tomography Project Summary/Abstract We propose to significantly improve the diagnostic imaging capab...

Objectives: The frequency of chromosomal aberrations (CA) and micronuclei (MN) in peripheral blood lymphocytes was compared in two groups of persons occupationally exposed to tritium either through the use of luminous paints or in the weapons industry, with the aim of finding a correlation between the CA and MN assays, the extent of radiation hazard, and the duration of occupational exposure to chemical forms of tritium and the ability of the latter to induce hazards in human lymphocytes. Methods: CA analysis and the cytochalasin B micronucleus test were performed. Urinary tritium in both groups was measured using a liquid scintillation method. For purposes of comparison, 2 control groups (40 persons) were examined; 24 exposed individuals were matched to their controls according to age, sex, and smoking habits. Results: Values recorded for the frequency of CA in the group of workers handling tritium in luminous dial painting were 0.015 +/- 0.014 dicentrics/cell, 0.023 +/- 0.017 total u...nstable ...

Objectives: The frequency of chromosomal aberrations (CA) and micronuclei (MN) in peripheral blood lymphocytes was compared in two groups of persons occupationally exposed to tritium either through the use of luminous paints or in the weapons industry, with the aim of finding a correlation between the CA and MN assays, the extent of radiation hazard, and the duration of occupational exposure to chemical forms of tritium and the ability of the latter to induce hazards in human lymphocytes. Methods: CA analysis and the cytochalasin B micronucleus test were performed. Urinary tritium in both groups was measured using a liquid scintillation method. For purposes of comparison, 2 control groups (40 persons) were examined; 24 exposed individuals were matched to their controls according to age, sex, and smoking habits. Results: Values recorded for the frequency of CA in the group of workers handling tritium in luminous dial painting were 0.015 +/- 0.014 dicentrics/cell, 0.023 +/- 0.017 total u...nstable ...

BCNU (carmustine), 5-Fluorouracil (5-FU) and Vidarabin-monophosphate (ARA-A5P) were compared in their activities against 30 cell lines of primary (n = 21) and metastatic (n = 9) brain tumors, which were characterized in tissue culture by cytochemical, immunological and cytogenetic criteria. In vivo achievable concentration-time products were correlated with in vitro pharmacokinetic data. A micro assay was employed to screen for drug toxicity in individual tumor cell lines; cells were exposed to the drugs at exposure doses relevant to in vivo pharmacokinetics. After 5-8 population doubling times of untreated controls, RNA-synthesis, as a parameter of cell metabolism and proliferation, was determined by incorporation of (5, 6-3H)-uridine into cellular RNA (liquid scintillation counting protocol). A tumor stem cell assay was performed under similar conditions. The cytotoxic effect of each drug on individual cell lines was expressed in terms of a sensitivity index SI (SI = 1 indicating complete ...

To assess the validity of myocardial imaging with potassium-43 (43K) early after the onset of ischemia, the left anterior descending artery was occluded with a baloon tip catheter in 32 intact anesthetized dogs. 99mTechnetium ventriculograms localized the left ventricle. 43K was administered intravenously and serial images were obtained in four views using an Anger camera with a pinhole collimator. The heart was arrested after 60 minutes and removed for imaging and tissue counts to ascertain extracardiac and geometric factors. In normals (group 1) left ventricular images were relatively homogeneous, except for the thin walled apex, both in vivo and in the isolated heart. Equilibration with 43K prior to ischemia (group 2) gave similar images to group 1, associated with a small reduction in tissue count after one hour of ischemia. Group 3 was infused with 43K after initiation of ischemia. Despite a reduction of 43K counts in the ischemic area to less than one-fourth of the nonischemic site (P less ...

The flagship monthly journal of SPIE, |i|Optical Engineering|/i| (OE) publishes peer-reviewed papers reporting on research and development in all areas of optics, photonics, and imaging science and engineering.

Scintillator crystal detectors form the basis for many radiation detection devices. Therefore, a search for high light yield single crystal scintillators with improved energy resolution, large volume, and the potential for low cost, is an ongoing process that has increased in recent years due to a large demand in the area of nuclear isotope identification. Alkaline earth halides, elpasolites and rare earth halides are very interesting because many compositions from these crystal families provide efficient Ce3+/ Eu2+ luminescence, good proportionality and good energy resolution. They also have small band-gap leading to higher light yields. Ce3+and Eu2+ are efficient, and the emission wavelengths in the 350-500 nm region matches well with PMTs and a new generation of Siphotodiodes. In this presentation, we will the present progress made in the crystal growth of these compositions, and scintillator properties of large diameter SrI2:Eu2+ single transparent crystals. The crystals were grown ...

QuiremSpheres® microspheres, which are based on holmium-166, provide unique imaging capabilities that allow for optimum in vivo dosimetry on a voxel level. This makes it possible to perform post-treatment quantitative verification of the achieved dose distribution, i.e. determining dose-to-tumor and dose-to-tissue. With QuiremSpheres® you treat what you see and see what you treat. Read more ...

QuiremSpheres® microspheres, which are based on holmium-166, provide unique imaging capabilities that allow for optimum in vivo dosimetry on a voxel level. This makes it possible to perform post-treatment quantitative verification of the achieved dose distribution, i.e. determining dose-to-tumor and dose-to-tissue. With QuiremSpheres® you treat what you see and see what you treat. Read more ...

China Security Dome CCTV CCD Camera / Explosion-Proof PTZ CCD Camera (SHJ-525CZ-36B), Find details about China Cctv Camera, Ccd Camera from Security Dome CCTV CCD Camera / Explosion-Proof PTZ CCD Camera (SHJ-525CZ-36B) - Changzhou Shengshijia Electronic Co., Ltd.

An intensified-CCD detector system has been developed for use in space (and elsewhere) which has application over a wide range in wavelength and which can be used at the focal plane of a variety of instruments (spectrographs, imagers, interferometers). This detector involves components which are readily available and mechanically, thermally, and optically coupled to produce the final compact system. The CCD is cooled using a Peltier effect thermoelectric cooler to reduce thermal noise. The image is formed on the photocathode of a proximity focused image intensifier and is transferred fiber optically from the intensifier to the CCD. Various photocathode and window materials are used to optimize the system for use within the wavelength range extending from the far UV to the near IR. In the case of the extreme UV, a windowless intensifier is used. In the case of those photocathode materials that require cooling to reduce thermally generated counts, an additional thermoelectric cooler is used at the ...

Marti, L, Ikeda, M, Kato, Y et al. (65 more authors) (2020) Evaluation of gadoliniums action on water Cherenkov detector systems with EGADS. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 959. 163549. ISSN 0168-9002 ...

First investigations in our laboratory were carried out using etched nano capillaries in a PET foil. These nano-capillaries had diameters of the order of 100nm at a length of several microns. A beam of highly-charged-ions was used to irradiate the foil, which could be tilted against the beam axis. The transmitted ions were recorded with a position sensitive detector system, allowing a time resolved determination of the deflection. Latest experiments were using a single, macroscopic glass tube, with a diameter of about 170 microns and a total length of more than 10 mm, showing also guiding up to several degrees, as illustrated in the figure. One can see the 2D image of the direct beam collimated by a 500 micron aperture at the capillary position (red) in comparison to the ions transmitted through the capillary (blue) at 4 different tilt angles. The experiments have been carried out with our ECR ion source, using 4.5keV Ar9+ projectiles. ...

Medical Detection Dogs dogs are able to sniff out some of the most aggressive forms of cancer thanks to their training. This training, however, takes time, hence the researchers desire to create a faster process using devices and AI. Results from the study showed that these trained dogs correctly identified positive prostate cancer samples 71 percent of the time, and correctly ignored negative samples - including people with other prostate diseases.. The robotic nose mimics this sniffing ability to detect such diseases thanks to an electronic device - which could one day come in the form of an app. Dr. Andreas Mershin, co-author of the study and from MIT, said Imagine a day when smartphones can send an alert for potentially being at risk for highly aggressive prostate cancer, years before a doctor notices a rise in PSA levels.. Mershin and the team have been working on their device over the past few years, which currently comes in the form of a miniaturized detector system that ...

The MultiRAE Pro wireless portable monitor can be used for radiation and advanced chemical detection. IScientific Pte Ltd has offers MultiRAE Pro gas detector system to detect Oxygen, LEL, CO, NO2, SO2, PH3, NH3, ClO2, Chlorine, CO2, EtO2, HCN, NO, Formaldehyde, H2S, VOCs etc.. ...

When employing specular reflective material in a scintillator crystal array, light trapping in the crystal due to repetitive internal reflection is mitigated by roughening at least one side (16) of each of a plurality of pre-formed polished scintillator crystals. A specular reflector material (30) is applied (deposited, wrapped around, etc.) to the roughened crystals, which are arranged in an array. Each crystal array is coupled to a silicon photodetector (32) to form a detector array, which can be mounted in a detector for a functional scanner or the like.

Flat panel devices for x-ray imaging that can be directly coupled to a commercial CCD for real-time radiography. Suitable for a wide range of fields from industrial x-ray inspection to medical x-ray exams.

The S12497 is a Si photodiode suitable for non-destructive inspection of baggage and the like and general industrial measurement. As it is a back-illuminated photodiode, photosensitive area does not have wires, and therefore a scintillator can be mounted directly on the photodiode.Features- Spectral response range : 400 to 1100 nm- Photosensitive area: 9.5 × 9.5 mm- Easy scintillator mounting