Age Related Survival and Spontaneous Disease Phenotypes in Selected Genetically Diverse Inbred Laboratory Mice is a study designed to develop a comprehensive reference benchmark database and clinical evaluation of 10 genetically diverse inbred strains of classical laboratory and wild-derived mice. ...
Evidence presented in this report shows that introduction of a novel autoantigen into the spontaneous disease process in the NOD mouse had no significant impact on incidence of type 1 diabetes and only led to a minimal acceleration of the disease course. This was quite unexpected, because antigenic spreading is responsible for relapses in the EAE model for multiple sclerosis and was therefore thought of as a hallmark event in the pathogenesis of T-cell-mediated autoimmune disorders. One could hypothesize, based on these findings, that the autoimmune process in the NOD model is already driven by a variety of antigens at the time when nucleoprotein-specific T-cells are being activated in the PDLNs. Therefore, the impact of one additional antigen is rather limited. Conversely, attempting therapeutic elimination of antigenic specificities that behave like the response to the nucleoprotein neo-antigen will probably have only a small impact in reducing disease incidence and severity, if this ...
Mouse, (genus Mus), the common name generally but imprecisely applied to rodents found throughout the world with bodies less than about 12 cm (5 inches) long. In a scientific context, mouse refers to any of the 38 species in the genus Mus, which is the Latin word for mouse. The house mouse (Mus
Basombrio, M., J. Nasser, M. Segura, L. Gomez. 1997. Trypanosoma Cruzi: Effect of immunization on the risk of vector-delivered infection in guinea pigs. The Journal of Parasitology, Vol. 83, No. 6: 1059-1062. Bloom, B. 1994. Tuberculosis: pathogenesis, protection, and control. Washington D.C.: American Society for Microbiology. Braastad, B. 1998. Effects of prenatal stress on behaviour of offspring of laboratory and farmed mammals. Applied Animal Behaviour Science, Volume 61, Issue 2: 159-180. Cassini, M. 1991. Foraging under predation risk in the wild guinea pig cavia aperea. Oikos, Vol. 62, No. 1: 20-24. Cassini, M., M. Galante. 1992. Foraging Under Predation Risk in the Wild Guinea Pig: the effect of vegetation height on habitat utilization. Annual Zoological Fennici, Vol. 29: 285-290. Dittmar, K. 2002. Arthropod and helminth parasites of the wild guinea pig, cavia aperea, from the andes and the cordillera in peru, south america. The Journal of Parasitology,, Vol. 88, No. 2: 409-411. ...
ID CAVPO0_15_PE7 STANDARD; PRT; 101 AA. AC CAVPO0_15_PE7; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE Flags: Fragments; DE (CAVPO0_15.PE7). OS CAVIA PORCELLUS. OC Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; OC Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; OC Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; OC Euarchontoglires; Glires; Rodentia; Hystricognathi; Caviidae; Cavia. OX NCBI_TaxID=10141; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CAVPO0_15.PE7. CC Cavia porcellus scaffold scaffold_0 cavPor3 partial sequence CC 13925120..14925119 annotated by Ensembl CC -!- GENE_FAMILY: HOG000007355 [ FAMILY / ALN / TREE ] DR HOGENOM:Cavia_porcellus;ENSCPOG00000010988;ENSCPOT00000011089;ENSCPOP00000009876. DR HOGENOMDNA; CAVPO0_15.PE7; -. KW ENSCPOG00000010988fold_1320000031; ENSCPOP00000009876fold_1320000031. SQ ...
ID CAVPO0_15_PE5 STANDARD; PRT; 213 AA. AC CAVPO0_15_PE5; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE (CAVPO0_15.PE5). OS CAVIA PORCELLUS. OC Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; OC Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; OC Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; OC Euarchontoglires; Glires; Rodentia; Hystricognathi; Caviidae; Cavia. OX NCBI_TaxID=10141; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CAVPO0_15.PE5. CC Cavia porcellus scaffold scaffold_0 cavPor3 partial sequence CC 13925120..14925119 annotated by Ensembl CC -!- GENE_FAMILY: HOG000073537 [ FAMILY / ALN / TREE ] DR HOGENOM:Cavia_porcellus;ENSCPOG00000001059;ENSCPOT00000001070;ENSCPOP00000000956. DR HOGENOMDNA; CAVPO0_15.PE5; -. KW ENSCPOG00000001059fold_1320000031; ENSCPOP00000000956fold_1320000031. SQ SEQUENCE 213 AA; ...
Bezsrst mor ata - jsou m lo roz en a proto nen snadn sehnat o nich n jak informace. P vodn byla vy lecht na b l ervenook mor ata. Z laborato se tento druh dostal k chovatel m, kte jej k ili s kr tkosrst mi mor aty. T m z skali adu
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis.
Cavia porcellus is the guinea pig that has been domesticated to become the pet guinea pig and its scientific classification is shown below.
Casein kinase (CK) 1δ/ε is a key component of non-canonical Wnt signaling pathways, which were shown previously to drive pathogenesis of chronic lymphocytic leukemia (CLL). In this study we investigated thoroughly the effects of CK1δ/ε inhibition on the primary CLL cells and analyzed the therapeutic potential in vivo using two murine model systems based on the Eµ-TCL1-induced leukemia (syngeneic adoptive transfer model and spontaneous disease development), which resemble closely the human CLL. We can demonstrate that CK1δ/ε inhibitor PF-670462 significantly blocks microenvironmental interactions - chemotaxis, invasion and communication with stromal cells in primary CLL cells in all major subtypes of CLL ...
According to Wikipedia: " Rats are various medium-sized, long-tailed rodents of the superfamily Muroidea. "True rats" are members of the genus Rattus, the most important of which to humans are the black rat, Rattus rattus, and the brown rat, Rattus norvegicus. Many members of other rodent genera and families are also … Continue reading →. ...
This tranquil bushland setting available to the public showcases display gardens of the wonderful flora from various parts of Australia while focusing on those plants endemic to our region. The 1.5 ha site was established in 1964 and is now under the authority of the Bankstown City Council and the Georges River Parkland Trust.. Part of these magnificent gardens feature the richly diverse flora of a typical Hawkesbury Sandstone outcrop while the Dry Rainforest forms a canopy over the fern understorey. Look out for the amazing display of orchids!. For further information on Sylvan Grove Native Gardens, click on the following link.. Bankstown City Council - Sylvan Grove Native Gardens ...
Rats are long-tailed rodents that are present in the world in various sizes, colors and shapes. They are larger in size when compared to mice. The two most common types are brown rats and black rats. The brown rats are also known as Norway rats. The black rats are believed to have originated in the Asian regions before slowly making their way to other parts of the world. An adult black rat can be around 30 to 46 cms in length. They are omnivorous in nature and feed on both plants and small insects or animals. They are also very generic in their food and eat about everything they can find. Not only do they feed on fruits, seeds, leaves and stems but also the food stuffs meant for cows, dogs, cats and chickens. They also are a big threat to farmers and destroy agricultural based crops. A Norway rat is around 25 cm in length with a tail that is usually as long as they are. They weigh around 250 to 350 grams. They are known to have originated from China and are an important model of scientific ...
A Brazilian Guinea Pig (Cavia aperea) sitting in grass at the Hellabrunn Zoo. Guinea pigs are rodents and classified as mammals.
Dunnum, J. L., & Salazar-Bravo, J. 2010. Molecular systematics, taxonomy and biogeography of the genus Cavia (Rodentia: Caviidae). Journal of Zoological Systematics and Evolutionary Research 48 (4): 376-388. doi: 10.1111/j.1439-0469.2009.00561.x ...
Anthony & Sylvan, Americas Premier Swimming Pool Builder, has been bringing family and friends together for more than 65 years.
Anthony & Sylvan, Americas Premier Swimming Pool Builder, has been bringing family and friends together for more than 65 years.
Fungal spores in the stomach contents and/or feces of 696 Peromyscus spp. showed that about half had eaten fungi: of 486 deer mice (P. maniculatus), 48%; of 160 white-footed mice (P. leucopus), 59%; of 40 canyon mice (P. crinitus), 12%; and of 10 pi ñ on mice (P. truei), 90%.
Rats are hardy creatures and adapt well to most environments. Unfortunately, buildings and homes are ideal sources of food and nesting for many rat populations. You might have rats in your house if you hear scratching and squeaking sounds at night, or notice feces in the home. Its important to take care of a rat problem promptly because they are prolific breeders. One female can have up to 18 litters of seven or more rats in a year.. ...
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Scientific laboratories frequently use rats for studies of behavioral psychology, as well as the effects of drugs or radiation. Rats can be kept as pets, although it is unwise for a child to try to tame a wild rat found in a slum. Like gerbils and hamsters, they must be raised in a sterile environment before being brought into your home, lest an accidental bite infect you with a deadly disease. They are usually kept in a cage or a terrarium, sometimes with other rats or mice. Domestic rats are curious, clean, and gentle creatures with a lifespan of approximately three years. ...
Webster University Presents Embracing Diversity and Inclusion: Critical Conversations. A conference to be held on the Webster Groves campus, Feb. 29-March 1, 2016.
The guinea pig also called the cavy. Despite their common name, these animals are not in the pig family nor are they from Guinea. They closely related species of cavy such as Cavia aperea, C. fulgida, or C. tschudii therefore, they do not exist naturally in the wild.. ...
TheInfoList.com - (Rodent) ANOMALUROMORPHA Anomaluromorpha CASTORIMORPHA Castorimorpha HYSTRICOMORPHA (inc. CAVIOMORPHA ) MYOMORPHA SCIUROMORPHA Combined range of all rodent species (not including introduced populations)RODENTS (from LATIN Latin rodere,
Two strains of Gram-positive cocci were isolated from viscera of common voles (Microtus arvalis Pallas) with generalized Brucella microti infection in the Czech Republic. Biochemical features and phylogenetic analysis based on 16S rRNA gene sequences showed that the strains are representatives of the genus Staphylococcus and assigned Staphylococcus muscae as the nearest relative. A detailed characterization done by ribotyping, rpoB and hsp60 gene sequencing, whole-cell protein analysis and rep-PCR using the (GTG)5 primer differentiated the two strains from all described staphylococci. DNA-DNA hybridization with the type strain of S. muscae demonstrated that the two strains should be considered as members of a novel species (26.8 % reassociation). The two analysed strains were found to be coagulase-negative, novobiocin-susceptible, oxidase-negative cultures, phenotypically close to one another, but showing differences in ribotype profiles. The major fatty acids were iso-C15 : 0, iso-C17 : 0, anteiso-C15
An adult feline blood donor, group-housed in a closed colony with other blood donor cats in a laboratory animal facility, developed anorexia, abdominal pain, an abdominal mass effect, and hemorrhagic diarrhea. Ultimately Salmonella infection was diagnosed. The index cat and 2 additional cats in the closed colony had clinical signs consistent with Salmonella and yielded Salmonella serotype 4,12:i:- in fecal cultures. An extensive search for the source of Salmonella was unrewarding. With the implementation of individual housing and additional barrier precautions, combined with antibiotic treatment of the index case, all the cats survived and subsequently had multiple, negative Salmonella PCR test results. This case report highlights the potential for unlikely infections to occur, even in a closed colony of research animals, as well as the important role of sanitation in the elimination of this enteric pathogen ...
A total of 20 healthy adult male guinea pigs were used in this study to investigate the anatomical, histological and morphometrical characteristics of the kidneys, ureter and urinary bladder. The gross anatomical study showed that the right kidney had a bean shape with reddish pink color whereas the left kidney had a heart shape. The renal cortex appeared darker than medulla with reddish brown color, while the medulla was pale in color. The mean thickness of cortex was more than that of medulla in both left and right kidneys and the ratio of cortex to medulla was 1.06: 1 in both kidneys. The mean length of right ureter was 10.3±0.62 cm while the mean length of left ureter was shorter. The filled urinary bladder appeared as a pear-shaped hollow sac situated in the pelvic cavity and only the rounded cranial part of bladder was expanded. Four histological regions of renal tubules were found in kidney. The Proximal convolutes tubule is first longest and coiled segment of renal tubules which originate from
Copyright: © 2017 Umba et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.. Abstract. To increase availability of animal proteins in Democratic Republic of the Congo (DRC), Cavia porcellus was recently enrolled in a breeding program that includes base populations from DRC and Belgium. To preserve whole or part of the sources genetic diversity over breeding cycles, cognizance of genetic diversity in natural populations is required. We tested the cross-amplification of eleven pairs of microsatellite primers that were isolated from Cavia aperea and C. magnea. Amplification tests by polymerase chain reaction were performed on total DNA of 30 C. porcellus using 11 microsatellite loci. All the microsatellites amplified at the expected size and were polymorphic for C. porcellus. Using these microsatellite loci, we ...
Consistent with a previous report on SDAV structural proteins (1), the coding sequences for the S, M, and N proteins were identified. Downstream of the S-protein gene, two overlapping potentially nonstructural-protein genes were located, and these were predicted to encode 15- and 12.6-kDa nonstructural proteins. A small internal ORF (ORF7b) was also found in the +2 frame within the N-protein-coding sequence. Following the N-protein gene, the 3′ untranslated region (UTR) was identified to be 298 nucleotides, followed by a stretch of polyadenylation tail.. The nonstructural NS2 gene, located immediately downstream of RNA polymerase gene 1b, has been shown to be heterogeneous in coronavirus. In MHV JHM variant Wb1, a large portion of the 5′ end of the NS2 gene is deleted, and as a result, the NS2 protein is not expressed (29). However, in SDAV the NS2 nonstructural-protein gene was identified to code for a polypeptide of 274 amino acids.. Similar to the NS2 gene, the hemagglutinin-esterase (HE) ...
Wild rats, Rattus spp, have adapted so well to urbanization that humans may be obligatory to their survival. Consequently, rats foul human food sources, predate threatened fauna and serve as reservoirs for disease, costing the US economy $19 billion in losses year -1. Urban rat ecology however, remains vastly unexplored because these animals are cryptic, crepuscular, difficult to identify, and hazardous to handle. Additionally, the high-rise buildings that block satellite link-ups, underground sewers and subway tunnels, and rebar enforced concrete covered landscape make it difficult-if not impossible- to track urban animals using traditional radio telemetry. Consequently, there are few ecological studies with free-ranging urban rats. Therefore, we set out to monitor the behaviors and health of free-ranging rats in metropolitan New York. Recognizing that wild rats are attracted to live laboratory-reared conspecifics and that they are sensitive to pheromones, we used soiled rat bedding to repeatedly
Context.: In many parts of the world, brown rats have colonised sewer systems and the rat populations in sewers are often thought to be a source of problems with rats on the surface. The management of sewer rat populations is usually performed with little, if any, knowledge of the dynamics and behaviour of these populations. Aims.: The study aimed to uncover the population dynamics, movements and distribution of rats in populations living in sewers. Methods.: We studied rats in a capturemarkrecapture study in two adjacent but separate sewer systems in suburban Copenhagen, Denmark, covering a surface area of 30 Ha. Multiple-capture live traps were placed in manholes in public sewers; animals were marked individually and data were collected every fourth week for a period of almost 3 years. Key results.: In total, 332 individual rats were trapped. Approximately one-third were only caught once, half of these were juveniles. The median time an individual was present in the sewers was 4 months with ...
Pagès, M., Bazin, E., Galan, M., Chaval, Y., Claude, J., herbreteau, V., Michaux, J., Piry, S., Morand, S. and Cosson, J.-F. (2013), Cytonuclear discordance among Southeast Asian black rats (Rattus rattus complex). Molecular Ecology, 22: 1019-1034. doi: 10.1111/mec.12149 ...
Guinea pig The guinea pig (Cavia porcellus), also called the cavy, is a species of rodent belonging to the family Caviidae and the genus Cavia. Despite their common name, these animals are not in the pig family, nor are they from Guinea. They originated in the Andes, and earlier studies based on biochemistry and hybridization…
The common brown rat (Rattus norvegicus) is a highly destructive rodent pest found in and around rural and urban settings. Call us for rat control service.
The domestication of guinea pigs dates back hundreds of years. Animals raised for food or the laboratory are of a species (Cavia porcellus) that is not found in the wild. Its closest relatives are the Brazilian guinea pig (C. aperea) and the montane guinea pig (C. tschudii) from western South America including Peru. ...
A mouse (plural: mice) is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate. The best known mouse species is the common house mouse (Mus musculus). It is also a popular pet. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable both to breeding and to different conditions in the wild. The most well known strain, the white lab mouse, has more uniform traits that are appropriate to its use in research. The American white-footed mouse (Peromyscus leucopus) and the deer mouse (Peromyscus maniculatus), as well as other common species of mouse-like rodents around the world, also sometimes live in houses. These, however, are in other genera. Cats, wild dogs, foxes, birds of prey, snakes and even certain kinds of arthropods have been known to prey heavily ...
La Edición 138 Síndrome de Horner en perros y gatos - revisión ,Quistes ováricos en cobaya (Cavia porcellus) - relato de caso ,Lept.. e mucho m?s
Ward C.R., Achenbach S.E., Holt D., et al. , 2005. 15(2): p.114-20. Feline hyperthyroidism is a common, spontaneous disease in older cats that is similar
Rederivation. The Transgenic Facility provides rederivation services to all AECOM investigators seeking to maintain or save cell lines/strains. We advise that individual labs refrain from waiting until candidate mice are over 4 months, as advanced age decreases the chances of rederivation success. Investigators must contact the Transgenic Facility Director to schedule the procedure as well as discuss the details of candidate cell lines/strains and obtain and complete a Transgenic Rederivation Form. Scheduling is on a first come-first served basis. Individual investigators are responsible for the super ovulation and mating of candidate mice. Once a target date has been agreed upon, investigators must obtain super ovulation hormones and a tube of embryo-specific media from the facility. Information on super ovulation scheduling is provided. Training for either plug checking or oviduct isolation can also be arranged with the facility director. The super ovulation hormones used are Pregnant Mare ...
Domain architecture and assignment details (superfamily, family, region, evalue) for ENSRNOP00000028137 from Rattus norvegicus 69_3.4. Plus protein sequence and external database links.
Two main types of rats, brown rats and black rats eat about the same things. But there are slight differences in preferences between the two. Brown rats or Norway rats eat nearly any type of food, but they prefer high-quality foods such as meat and fresh grain. These rats require 1/2 to 1 fluid ounce of water daily when feeding on dry food ...
Mouse monoclonal antibody raised against native human HLA-DR. Mononuclear cell leukemia acute undifferentiated. (MAB15424) - Products - Abnova
Mouse monoclonal antibody raised against native human HLA-DR. Mononuclear cell leukemia acute undifferentiated. (MAB15428) - Products - Abnova
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... ...
This is a clone of the SV40LT-SMC cell line derived from primary abdominal aortic tissue from young rats. The parental line was created by immortalizing the primary cells by transfection with SV40 large T antigen.
Li CY, Mao X, Wei L; Genes and (common) pathways underlying drug addiction.; PLoS Comput Biol, 2008 PubMed Europe PMC ...
In a way, studying the rat is like studying a human. As the leading theme of this lab, ask yourself: for every structure observed in the rat, there is an equivalent structure in your own body what is the structure and where is it located?
K01186 NEU1; sialidase-1 [EC:3.2.1.18] K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18] K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18] K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18] K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18 ...