TY - JOUR. T1 - Emotional impact on the results of BRCA1 and BRCA2 genetic test. T2 - An observational retrospective study. AU - Mella, Sara. AU - Muzzatti, Barbara. AU - Dolcetti, Riccardo. AU - Annunziata, Maria Antonietta. PY - 2017/10/2. Y1 - 2017/10/2. N2 - Background: BRCA1 and BRCA2 mutations are associated with a higher risk of breast and ovarian tumors. This study evaluated the emotional states of women 1 month after having received the results of the genetic test and assessed eventual associations with the type of outcome, personal/familiar disease history and major socio-demographic variables. Methods: The study, an observational retrospective one, involved 91 women, evaluated 1 month after receiving their results. Patients were administered the Hospital Anxiety and Depression Scale, the Profile of Mood States and emotional Thermometers. Results: Anxiety was significantly higher than depression (p , 0.001), and 21.3% and 21.3% of the sample were, respectively, possible and probable ...
Background: In the case of life-threatening conditions such as respiratory or cardiac arrest, or the clinical deterioration of the patient, a Code Blue activation may be instigated. A Code Blue activation involves a team of advanced trained clinicians attending the emergency needs of the patient. Aims and objectives: The aim of the study was to explore the number of cases of Code Blue activations, looking at the timing, clinical ward, diagnosis and activation criteria while noting cases where escalation from a Medical Emergency Team (MET) call occurs in one Regional Healthcare Service in Victoria, Australia, over a six-year period. Methods: A quantitative retrospective descriptive study of Code Blue emergencies over a six-year period from June 2010 to June 2016 was conducted. Data collected from the RISKMAN program operating at a single site was imported into SPSS (V 22) for descriptive statistical analysis. A STROBE EQUATOR checklist was used for this study (see File S1). Findings: The majority ...
Game Coaching System Design and Development: A Retrospective Case Study of FPS Trainer: 10.4018/ijgbl.2013040105: This paper is a retrospective case study of a game-based learning (GBL) researcher who cooperated with a professional gamer and a team of game developers to
TY - JOUR. T1 - Blood transfusion during cesarean section. A 12 years retrospective analysis.. AU - Imberti, R.. AU - Preseglio, I.. AU - Trotta, V.. AU - Filisetti, P.. AU - Mapelli, A.. PY - 1990. Y1 - 1990. N2 - Transfusional practice over the last 12 years was investigated retrospectively in 1618 women submitted to lower-segment cesarean section. The overall percentage of transfused patients was low (2.4%) and it has become lower in the last four years (1.1%), in concomitance with the development of better knowledge of tissue oxygenation and with the fear of transmitting infectious diseases, factors which have led anesthesiologists to employ blood only when strictly required. Three conditions greatly increased the risk of bleeding: placenta previa, abruptio placentae and coagulation disorders. Previous cesarean section, fetal distress, dystocias and hypertensive disorders of pregnancy did not increase the risk of bleeding and no difference was found between elective and non-elective ...
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Read "Risk Factors for Poor Compliance with Adjuvant S-1 Chemotherapy for Gastric Cancer: A Multicenter Retrospective Study, Annals of Surgical Oncology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
A total of 182 patients were included in this study. Of all the 182 patients, 126 were male (69.23%) and 56 were female (30.77%). The mean age was (56.75±12.45) years. The median follow-up time was 48 months (3-99 months). At the end of the follow-up, 50 patients (27.47%) died due to the disease after a median of 29.74 months and 59 patients (32.42%) had tumor recurrence after a median of 22.12 months. The 5-year cancer-specific survival of all patients was 68.30% (95% CI: 60.16%-75.84%); the 5-year recurrence-free survival was 60.70% (95% CI: 53.16%-68.84%). In the univariate analysis, diabetes mellitus, tumor invasion status, Fuhrman grade, serum album, serum cholestenone, anemia, and neutrophils percentage were associated with the cancer-specific survival and Fuhrman grade, serum album and anemia were associated with the recurrence-free survival. Variables with significant differences on univariate analysis were included in Cox multivariate regression analysis. Multivariate Logistic ...
Tyner, G A and Nolen-Walston, R D and Hall, T and Palmero, J P and Couetil, L and Javsicas, L and Stack, A and Schott, H and Johnson, A and Hardefeldt, L and Gruntman, A and Sommardahl, C and Menzies-Gow, N J and dePedro, P and Norman, T and Fennell, L C and Axon, J E and Lindborg, S and Aceto, H and Boston, R and Engiles, J (2011) A Multicenter Retrospective Study of 151 Renal Biopsies in Horses. JOURNAL OF VETERINARY INTERNAL MEDICINE, 25 (3). pp. 532-539. Full text not available from this repository ...
Older people frequently attend the emergency department (ED) and have a high risk of poor outcome as compared to their younger counterparts. Our aim was to study routinely collected clinical parameters as predictors of 90-day mortality in older patients attending our ED. We conducted a retrospective follow-up study at the Leiden University Medical Center (The Netherlands) among patients aged 70 years or older attending the ED in 2012. Predictors were age, gender, time and way of arrival, presenting complaint, consulting medical specialty, vital signs, pain score and laboratory testing. Cox regression analyses were performed to analyse the association between these predictors and 90-day mortality. Three thousand two hundred one unique patients were eligible for inclusion. Ninety-day mortality was 10.5 % for the total group. Independent predictors of mortality were age (hazard ratio [HR] 1.06, 95 % confidence interval [95 % CI] 1.04-1.08), referral from another hospital (HR 2.74, 95 % CI 1.22-6.11),
Of the 87,702 new adult TB cases in the Free State (2009-2012), 22.8% had an unsuccessful TB treatment outcome, the majority of these cases (18.3%) were co-infected with HIV. As HIV is one of the major factors fuelling the growing TB epidemic [20, 25, 26] - 61% of the TB cases in the province were co-infected with HIV/AIDS, which was slightly lower than the 65% average reported over the same period for South Africa [27] - the analysis of data in this paper was stratified by HIV status. During the study period (2009-2012), the HIV status of the majority (81.4%) of cases was known. In line with the WHO [19] recommendation that all patients with (presumptive) TB be offered HIV testing, it is encouraging to note that by 2014, there was a substantial improvement in the country as a whole, with 93% of TB patients knowing their HIV status [1]. Similarly to other studies [1, 4-7] we found significant differences in treatment outcomes between patients who were HIV-negative and HIV-positive. Over the four ...
Incidental appendectomy--yes or no? A retrospective case study and review of the literature.: The data from the current survey and literature review support inc
This study evaluated the long-term clinical outcomes between Resolute zotarolimus-eluting stent and paclitaxel-eluting stent in patients with small coronary
Three laboratories present a harmonised system for the retrospective comparison of south west Asian heroin. It consists of an improved gas chromatographic (GC) profiling method and a computerised data retrieval. The investigations of the GC were necessary with a view to improve the reproducibility of the system. The necessity of a strict quality control is emphasized. The peaks of the GC profile were investigated for abundance, intensity, GC behaviour (reproducibility) and correlations, 16 of them were selected for describing the heroin profile in the database. The results from intra-lab profile comparisons are reported. The reproducibility of the analysis was good and the variation between the samples was large, thus, allowing conclusions with a high degree of certainty. The criteria of similarity were defined. The system is successfully running in all three labs. In connection with inter-laboratory comparison, the aspects of method harmonisation and standardisation are discussed. It appeared ...
In this multicenter retrospective study, the outcomes of 836 patients with myelodysplastic syndrome (MDS) who underwent transplantation with a human leukocyte antigen (HLA)-identical sibling donor were analyzed according to 2 types of conditioning: reduced-intensity conditioning (RIC) in 215 patients, and standard myeloablative (or high-dose) conditioning (SMC) in 621 patients. In multivariate analysis, the 3-year relapse rate was significantly increased after RIC (hazard ratio [HR], 1.64; 95% confidence interval [95% CI], 1.2-2.2; P = .001), but the 3-year nonrelapse mortality (NRM) rate was decreased in the RIC group (HR, 0.61; 95% CI, 0.41-0.91; P = .015). The 3-year probabilities of progression-free and overall survivals were similar in both groups (39% after SMC vs 33% in RIC; multivariate P = .9; and 45% vs 41%, respectively; P = .8). In conclusion, the lower 3-year NRM after RIC is encouraging, since these patients were older (age > 50 years in 73% RIC vs 28% in SMC, P < .001) and ...
Citation : Rutty J E, Woodward H and Rutty G N (2000) A 50 year retrospective study of height, weight and body mass index at the time of death in those aged 16-103. Royal College of Nursing Research Society Annual Conference (Sheffield), 13-15 April ...
Abstract Objective The objective of this retrospective descriptive study was to assess overall survival and disease free survival of patients treated for epithelial ovarian cancer by a gynaecologic-oncologist in a single Dutch peripheral teaching hospital and to identify independent prognostic factors. Study design A retrospective series of 242 patients treated ... read more for epithelial ovarian cancer between 1999 and 2011 at Meander Medical Centre was reviewed. Data on patient, tumour and treatment characteristics were collected. Outcomes were overall survival and progression free survival. Data were analysed using the Kaplan-Meier method, log-rank test and Cox regression analysis. Results Median follow-up was 35 months (range 1-203). Staging procedures were performed in 81 patients of which 63% were complete. 61% of patients had advanced stage disease. In 46%, debulking surgery was complete. Five-year overall survival and progression free survival for all patients was 52% and 47%, ...
This study investigated clinical outcome and post-progression management in a large cohort of French patients with ALK+ NSCLC treated with crizotinib.
In absence of patient-level databases, multi-national, retrospective chart review studies can be undertaken to provide robust naturalistic data to inform evaluations of treatment patterns, resource utilization, costs of care, clinical outcomes and safety.
TY - JOUR. T1 - Depressive symptoms in the last days of life of patients with cancer: a nationwide retrospective mortality study. AU - Janberidze, Elene. AU - Pereira, Sandra Martins. AU - Hjermstad, Marianne Jensen. AU - Knudsen, Anne Kari. AU - Kaasa, Stein. AU - van der Heide, Agnes. AU - Onwuteaka-Philipsen, Bregje. PY - 2016/6. Y1 - 2016/6. U2 - 10.1136/bmjspcare-2014-000722. DO - 10.1136/bmjspcare-2014-000722. M3 - Article. VL - 6. SP - 201. EP - 209. JO - BMJ Supportive & Palliative Care. JF - BMJ Supportive & Palliative Care. SN - 2045-435X. IS - 2. ER - ...
Current ultrasound machines are capable of recording clips using two types of capture: Prospective and Retrospective data collection.
The present study was carried out in the postgraduate department of Pathology at Government Medical College, Srinagar, India, to study the histopathological pattern of thyroid lesions reported a tertiary care hospital in Kashmir retrospectively for a period of three years. During this study, 165 thyroidectomy specimens were analyzed. Their corresponding slides were retrieved and reviewed. Out of these, 37 cases were non-neoplastic and 128 were neoplastic. Among neoplastic cases 40 cases were benign, 87 cases were malignant and one case was diagnosed as having a well differentiated tumor of uncertain malignant potential. Peak incidence was in the third decade of life with female predominance. Among the malignant tumors, the highest incidence was that of papillary carcinoma of thyroid (83.90%), followed by follicular and medullary carcinoma (6.89% each). Colloid goitre (12.72%) was the most frequent entity in the benign category. The remarkable observation of this study was that the neoplastic ...
Background Childhood obesity is a significant health problem in the UK. To date, there is little known about the pattern of change in body mass index (BMI) following renal transplantation in UK paediatric patients. Our objectives in this study were to (i) describe trends in BMI seen in UK patients undergoing renal transplantation in the short and medium term and (ii) identify risk factors predisposing children to excessive weight gain following transplantation.. Methods A retrospective case note review was performed across 12 of 13 paediatric nephrology centres in the UK, with BMI measurements recorded pre-transplantation and for 4 years thereafter. BMI% was used to assess changes in adiposity over time. International Obesity Taskforce definitions of overweight and obesity…. Read Full Article. ...
In Chinese patients with diabetes, having hemoglobin A1c (HbA1c) levels that are too high or too low may be associated with a greater risk of cardiovascular disease and death, according to a research letter published Jan. 25 in the Journal of the American College of Cardiology.. In this population-based retrospective cohort study, Eric Yuk Fai Wan, MSc, CStat, of the University of Hong Kong, and colleagues examined 117,389 adult Chinese patients with type 2 diabetes without any history of cardiovascular disease. After a median follow-up of 54.5 to 58.5 months, a J-shaped curvilinear relationship was observed between HbA1c levels and cardiovascular disease incidence, all-cause mortality and other outcomes. An HbA1c range of ≥7.0 percent to ,7.5 percent had the lowest risk of new cardiovascular disease, coronary heart disease, stroke, heart failure, all-cause mortality and cardiovascular disease-related mortality. By comparison, an HbA1c ,6.5 percent or ≥8.0 percent was associated with a ...
Phospholipase Cγ1 (PLCγ1) is highly expressed in human tumours. Our previous studies reported that both stable and inducible PLCγ1 down-regulation can inhibit formation of breast-cancer-derived experimental lung metastasis. Further, high expression of PLCγ1 and its constitutively activated forms (i.e., PLCγ1-pY1253, PLCγ1-pY783) is associated with worse clinical outcome in terms of incidence of distant metastases, but not of local relapse in T1-T2, N0 breast cancer patients. In the present retrospective study, we analysed the prognostic role of PLCγ1 in early breast cancer patients stratified according to the St. Gallen criteria and to their menopausal status. PLCγ1-pY1253 and PLCγ1-pY783 protein expression levels were determined by immunohistochemistry on tissue microarrays, and were correlated with patients clinical data, using univariate and multivariate statistical analyses. In our series, the prognostic value of PLCγ1 overexpression was restricted to Luminal type tumours. From
The role of paternal factors in determining the risk of adverse pregnancy outcomes has received less attention than maternal factors. Similarly, the interaction between the effects of race and socioeconomic status (SES) on pregnancy outcomes is not well known. Our objective was to assess the relative importance of paternal vs. maternal education in relation to risk of low birth weight (LBW) across different racial groups. We conducted a retrospective population-based cohort study using Washington state birth certificate data from 1992 to 1996 (n = 264,789). We assessed the associations between maternal or paternal education and LBW, adjusting for demographic variables, health services factors, and maternal behavioral and obstetrical factors. Paternal educational level was independently associated with LBW after adjustment for race, maternal education, demographic characteristics, health services factors; and other maternal factors. We found an interaction between the race and maternal education on risk
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Although little debate exists on the need for advanced neonatal services for the most immature and surgically complex neonates, ongoing controversies exist regarding which facilities are qualified to provide these services and what is the most appropriate measure for such qualification. These issues are, in general, based on the need for comparison of facility experience (measured by patient volume or census), location (inborn/outborn deliveries, regional perinatal center, or childrens hospital), or case mix (including stillbirths, delivery room deaths, and complex congenital anomalies).. Several studies have explored the topic of center experience as measured by volume or census of VLBW infants.30-35 Phibbs et al conducted a population-based retrospective cohort study of 48 237 California VLBW infants to examine differences in neonatal mortality among NICUs with various levels of care and patient volumes. When compared with high-volume, high-level centers, the odds ratio of death was 1.19 ...
To quantify the risk and types of sequelae attributable to prior enteric infections, we undertook a population-based retrospective cohort study using linked administrative records. The risk for first-time hospitalization for sequelae was modeled by using Cox proportional regression analysis controlling for other health and sociodemographic factors. We identified a significant increase of 64% in the rate of first-time hospitalization for sequelae for persons with prior enteric infections: 52% for intragastrointestinal sequelae and 63% for extragastrointestinal sequelae compared with first-time hospitalization for those without prior infection. Extragastrointestinal sequelae occurred predominantly during the first 5 years after first-time enteric infection. In contrast, most intragastrointestinal sequelae occurred &gt;10 years later. Infective gastroenteritis during childhood or adolescence increases the risk for first-time hospitalization for intragastrointestinal and extragastrointestinal disease
In a retrospective population-based cohort study involving 92 735 older women with incident invasive breast cancer, Smith and colleagues compared risk of death,
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The impact of deferring critically ill children in referral hospitals away from their designated pediatric critical care unit (PCCU) on patients and the healthcare system is unknown. This population-based retrospective cohort studys goal was to identify the factors associated with deferrals of critically ill children away from their designated PCCU, evaluate patient outcomes as they related to deferrals away from a PCCU and study the impact of the 2010 referral policy implementation.
The EMC trial is unique because it investigates for the first time prospectively whether MDD patients with non-improvement after 14 days of AD treatment with EMC are more likely to become remitters compared to patients treated according to current guidelines, i.e., with a medication change after 28 days of treatment in case of non-response. All current evidences originate from retrospective data analysis, but not from prospective clinical trials: there is substantial evidence showing that non-improvement in the first 2 weeks of AD treatment is highly predictive for poor final outcome and leading experts in the field have repeatedly recommended the outcome evaluation in the early course of treatment as well as the consideration of early symptom changes in clinical decision making [23-27]. However, the entire knowledge about the predictive value of early improvement derives exclusively from retrospective data analyses. No study has yet prospectively investigated whether non-improvers (HAMD17 ...
臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。. To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of "NTU Repository" with "Academic Hub" to form NTU Scholars.. ...
Validation of the 7th AJCC/UICC staging system for gastric cancer and a proposal for a new TNM system based on a prognostic score: a retrospective multicenter study Ann Surg Treat Res. 2016 Dec;91(6):295-302. ...
Syed A. Abutalib, MD, of Cancer Treatment Centers of America, and Nelli Bejanyan, MD, of the University of Minnesota, discuss findings from a study conducted by the Center for International Blood and Marrow Transplant Research on treatment for ALL patients, with an available donor, undergoing myeloablative allogeneic hematopoietic cell transplantation in first complete remission (Abstract 684).. ...
Retrospective Analysis of charts on patients having undergone Total Hip or Total Knee Arthroplasty. During the patients hospitalization, lab values of Hg and Hct will be recorded for further analysis. Preoperative levels will be also noted to establish baselines.. Primary Data interest will be Hemoglobin (Hgb) level documented during hospitalization along with Hematocrit (HCT) and Red Blood Cell (RBC) data also collected.. Secondary Data gathered will consist of the following:. ...
... , Yüksel Maras, Berat Meryem Alkan, Fatma Fidan Yildiz, Sevgi Gümüs
BACKGROUND: Type 2 diabetes mellitus, gastric and hepatobiliary comorbidities, and cancer share common risk factors: for example, tobacco, obesity, physical inactivity, high calorie intake, and metabolic disorders. Prior studies find type 2 diabetes and gastric and hepatobiliary comorbidities heightening risk of pancreatic cancer. Yet joint association of type 2 diabetes mellitus and gastric and hepatobiliary comorbidities on pancreatic cancer risk has not been assessed. METHODS: This study rates independent/joint effects of type 2 diabetes as well as gastric and hepatobiliary comorbidity on pancreatic cancer risk for a retrospective population-based cohort of 166,850 type 2 diabetics identified in 1997-1998 and followed for 10-11 years, comparing their cancer incidence with that of 166,850 non-diabetics matched for age, gender, and locale ...
Despite existing evidence and guidelines advocating for appropriate risk stratification, ambulatory surgery in low-risk patients continues to be accompanied by a battery of routine tests prior to surgery. Using a single-center retrospective cohort study, we aimed to quantify the incidence of un-indicated preoperative testing in an academic ambulatory center by utilizing recommendations by the recently developed American Society of Anesthesiology (ASA)
Sigma-Aldrich offers abstracts and full-text articles by [Isabelle Pham, Emmanuel Cosson, Minh Tuan Nguyen, Isabela Banu, Isabelle Genevois, Patricia Poignard, Paul Valensi].
The precise role of CD26/DPP4 in tumor biology is unclear at this time. Preclinical studies have shown conflicting data with differential CD26/DPP4 expression and activity depending on the type of cancer. These studies suggest that it has a role as either a tumor suppressor or tumor activator depending on the tumor microenvironment and molecules with which CD26/DPP4 associates (1,3). However, since most of these studies involved in vitro assays, further investigations with in vivo experiments are needed to definitively establish the role of CD26/DPP4 in each cancer type.. Published studies have demonstrated that CD26/DPP4 plays a major role in the invasion and metastasis of selected cancers, and may be a novel therapeutic target (1,2,5,6). There are several suggested mechanisms for cancer metastasis involving the intrinsic peptidase activity of CD26/DPP4 and its subsequent chemokine regulation, as well as its ability to bind key molecules. For example, CD26/DPP4 can upregulate the expression of ...
DAMASCENO, Marcelo Loquette et al. Retrospective results analysis of the use of cranial fractures halo subaxial dislocations. Coluna/Columna [online]. 2010, vol.9, n.4, pp.376-380. ISSN 1808-1851. http://dx.doi.org/10.1590/S1808-18512010000400006.. OBJECTIVE: to evaluate the use of cranial halo cervical fractures and dislocations in the initial care related to the rate of successful closed reduction of cervical lesions in different types of fractures. METHODS: retrospective investigation of reports of patients admitted and treated from January 2004 to March 2009, a total of 222 patients. The lesions were categorized according to the AO classification. RESULTS: a high success rate of closed reduction in patients with cervical lesions by axial compression (AO type A) in the use of cranial halo; in distraction injuries (AO type B) and rotational motion (AO type C) we observed approximately 50% of closed reduction of dislocation; furthermore, lesions in more cranial levels have a higher success rate ...
INTRODUCTION: The development of new surgical techniques and medical devices, like therapeutical multimodal approaches has allowed for better outcomes on patients with rectal cancer (RCa). Owing to that, an increased awareness and investment towards better outcomes regarding patients sexual and urinary function has been recently observed. AIM: Evaluate and characterize the sexual dysfunction of patients submitted to surgical treatment for RCa. MATERIALS AND METHODS: An observational retrospective study including all male patients who underwent a surgical treatment for RCa between January 2011 December 2014 (n=43) was performed, complemented with an inquiry questionnaire to every patient about its sexual habits and level of function before and after surgery ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
EDEN PRAIRIE, Minn., Oct. 24, 2019 (GLOBE NEWSWIRE) -- CHF Solutions (Nasdaq: CHFS) today announced that investigators at Abington Hospital-Jefferson...
Journal of Dermatology and Clinical Research is an open access, peer reviewed academic Journal that deals with skin and its diseases.
This document contains guidance on how retrospective studies of a socio-economic analysis (SEA), conducted in support of a chemical risk management decision, can be carried out.
and at risk. They then use whatever records are available to determine each subjects exposure status at the begin of the observation period, and they then ascertain what subsequently happened to the subjects in the two (or more) exposure groups. Retrospective cohort studies are also longitudinal, because they examine health outcomes over a span of time. The distinction is that in retrospective cohort studies all of the cases of disease have already occurred before the investigators initiate the study. In contrast, exposure information is collected at the beginning of prospective cohort studies before any subjects have developed any of the outcomes or interest, and the at risk period begins after baseline exposure data is collected and extends into the future.. Retrospective cohort studies are particularly useful for unusual exposures or occupational exposures. For example, if an investigator wanted to determine whether exposure to chemicals used in tire manufacturing was associated with ...
Delayed gastric emptying (DGE) is the most frequent pancreatic specific complication (PSC) after pancreaticoduodenectomy (PD). Several gastric decompression systems exist to manage DGE. Patients with a pancreatic tumor require prolonged nutrition; however, controversies exist concerning nutrition protocol after PD. The aim of the study was to assess the safety and efficacy of nasogastric (NG), gastrostomy (GT), and gastrojejunostomy (GJ) tubes with different feeding systems on postoperative courses. Between January 2013 and March 2016, 86 patients underwent PD with pancreaticogastrostomy. Patients were divided into three groups: GJ group with enteral nutrition (EN, n = 12, 14%), NG (n = 31, 36%) and GT groups (n = 43, 50%), both with total parenteral nutrition (TPN). Patients in the GJ (n = 9, 75%) and GT (n = 18, 42%) groups had an American Society of Anesthesiologists (ASA) score of 3 more often than those in the NG group (n = 5, 16%, p ≤ 0.01). Multivariate analysis identified the GT tube with TPN
Colon cancer is a major public health problem. The primary treatment is resection. For patients with early-stage disease, surgery results in excellent survival rates. In contrast, patients with locally advanced tumors arising in anatomically immobile segments of large bowel have a less satisfactory outcome, in part secondary to compromised surgical clearance. Patterns-of-failure analyses suggest that for tumors that invade adjacent organs, exhibit perforation or fistula, or are subtotally resected, local failure rates exceed 30%. Multiple single-institution retrospective studies have shown improved local control and possibly survival with the addition of external irradiation and/or intraoperative radiation. In contrast, a recent Intergroup trial failed to show any benefit by the addition of adjuvant radiation therapy combined with chemotherapy. Interpretation of this trials results is handicapped by low patient accrual. With the advent of novel and more effective systemic therapies for metastatic
Xcenda uses retrospective database analyses for compliance and adherence assessments, analysis of treatment and population trends, economic and resource utilization analysis, and effectiveness studies.
From January 2003 to February 2016, a total of 110,698 patients were treated with anticoagulant and/or antiplatelet therapy at the participating medical centers. Among them, a total of 37 consecutive patients with SISBH were enrolled in this study. The annual incidence of SISBH was estimated at 0.003% per year. The study population comprised 19 males (51.4%), and the mean age at presentation with SISBH was 74.1 years (range, 51-89 years). Among these patients, 35 (94.6%) had cardiovascular comorbidities including 22 with hypertension (59.5%), 20 with cardiac arrhythmia (54.1%), 13 with a history of cerebrovascular accidents (35.1%), 10 with congestive heart failure (27.0%), 7 with coronary heart diseases (18.9%), 4 with pulmonary embolism and/or deep vein thrombosis (10.8%), 3 with a history of heart valve replacement (8.1%), and 2 with peripheral arterial diseases (5.4%). Three patients (8.1%) had malignant tumors at the time that SISBH presented, all of whom were being treated with systemic ...
Kurt Mahan, MD, of Presbyterian Healthcare Services discusses the results of his large retrospective database study evaluating post-discharge thromboprophylaxis among acutely ill hospitalized patients. 12,000 patients were included for this study, and the risk factors for mortality were evaluated. Antiplatelet and anticoagulant therapy omission was identified as a risk factor for mortality. No clear duration of post-discharge prophylaxis was identified, however the Kaplan Meier curves for death in this study showed the curves separate strongly between 15-30 days and remained strongly divergent at 45 days. While there is no well-defined timeline for duration of optimal post-discharge prophylaxis, this 30-45 days noted in this study may be suggestive. , TV Network
Inflammation of the central nervous system is a common cause of neurological manifestation in dogs. The confirmation of an inflammatory origin is made by cerebrospinal fluid (CSF) analysis. However, a tentative diagnosis and a prognosis are not always easy to give when the results of complementary tests are pending. The signalment, history, clinical and CSF findings of 90 dogs presenting confirmed inflammation of the central nervous system were reviewed. Our goal was to determine if a consensus was found among these parameters to be able to direct the diagnosis and the prognosis.. Materials and Methods. The medical records of 90 dogs admitted to the Clinique Fregis,Arcueil-France, between 1999 and 2001 were retrospectively reviewed. On all dogs CSF result had revealed a pleocytose of more than 10 cells per microliter. Case histories, signalment, general and neurological examination results, results of CSF analysis, other complementary exams (blood work, serology, PCR, CSF electrophoresis, ...
Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet
Reasons for performing study To determine risk factors involved in survival to hospital discharge of cases of synovial sepsis. Objectives Investigate pre-, intra- and post operative factors involved in short-term survival of horses undergoing endoscopic treatment for synovial sepsis. Study design Retrospective case series. Methods Clinical data were obtained for horses (,6 months old) undergoing endoscopic surgery as part of management for synovial sepsis over a 7-year period in a single hospital population. Descriptive data were generated for pre-, intra- and post operative variables. ...
In our study, there was a trend toward a low BMDa, particularly at the hip, in women with a history of JIA. BMDa was reduced particularly among patients with more severe disease as determined by disease subtype and level of function.. Ours is the first UK study to examine the effect of disease-related factors on bone health in adults with a history of JIA. It was a retrospective review of clinical practice at the time and accordingly, as with many such clinical outcome studies reliant on retrospective case note analysis, there are a number of limitations to consider. While all patients attending the clinic were offered a bone density scan, about 25% did not subsequently keep the appointment. It is possible that these patients may have differed with respect to bone mass levels from those who had a scan. Their omission may have resulted in an overestimate or underestimate of bone mass levels in the group, and the data need to be interpreted with some caution. It should not have influenced, ...
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Authors: Mazaris P, Hong X, Altshuler D, Schultz L, Poisson LM, Jain R, Mikkelsen T, Rosenblum M, Kalkanis S. Title: Key determinants of short-term and long-term glioblastoma survival: a 14-year retrospective study of patients from the Hermelin Brain Tumor Center at Henry Ford Hospital.. Journal: Clin Neurol Neurosurg 120:103-12. Date: 2014 May. Abstract: OBJECTIVE: Glioblastoma (GBM) is a heterogeneous neoplasm with a small percentage of long-term survivors. Despite aggressive surgical resection and advances in radiotherapy and chemotherapy, the median survival for patients with GBM is 12-14 months. Factors associated with a favorable prognosis include young age, high performance status, gross resection >98%, non-eloquent tumor location and O6-methylguanine methyltransferase (MGMT) promoter methylation. We retrospectively analyzed the relationship of clinical, epidemiologic, genetic and molecular characteristics with survival in patients with GBM. METHODS: This retrospective analysis of overall ...
Sargent DJ, Shi Q, Gill S, Louvet C, Everson RB, Kellner U, Clancy TE, Pipas JM, Resnick MB, Meyers MO, Wu TT, Huntsman D, Validire P, Farooq U, Pavey ES, Beaudry G, Haince JF, Fradet Y. Molecular testing for lymph node metastases as a determinant of colon cancer recurrence: results from a retrospective multicenter study. Clin Cancer Res. 2014 Aug 15; 20(16):4361-9 ...
A total of 1082 patients treated in 108 centers were studied. The median age was 72 years (range, 20 to 96). The disease stage was stage I in 415 patients (38.3%), stage II in 249 (23%), stage III in 255 (23.6%), and stage IV in 163 (15.1%) (FIGO 2009). The diagnosis was squamous cell carcinoma in 779 patients (72%), Pagets disease in 158 (14.6%), adenocarcinoma in 63 (5.8%), and others in 82 (7.6%). Positive lymph nodes were found in 237 patients (21.9%). The median tumor diameter was 35 mm (range, 1 to 180). The 5-year overall survival was 86% in stage I, 74.7% in stage II, 48.2% in stage III, and 39.3% in stage IV (P ...
An apparatus and method use ontological relationships in a query language and a computer database to improve database performance and utility. A set of ontological relationships are stored in the database and new query clauses are used to query the data in advantageous ways. Ontological relationships are preferably stored in a tree structure. This tree structure then can be used to reflect the ontological relationships of data stored in the columns of a database.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Lundar, Tryggve; Due-Tønnessen, Bernt Johan; Egge, Arild; Krossnes, Bård Kronen; STENSVOLD, EINAR; Due-Tønnessen, Paulina & Brandal, Petter (2015). Neurosurgical treatment of brain tumors in the first 6 months of life: long-term follow-up of a single consecutive institutional series of 30 patients. Childs Nervous System. ISSN 0256-7040. 31(12), s 2283- 2290 . doi: 10.1007/s00381-015-2792-5 Show summary Object The aim of this study is to delineate the long-term results for patients going through surgery for pediatric brain tumors in the first 6 months of life. Methods Thirty consecutive children (1-182 days old) who underwent primary resection for a brain tumor during the years 1973-2012 were included in this retrospective study on surgical morbidity, mortality rate, academic achievement, and/or work participation. Gross motor function and activities of daily life were scored according to the Barthel index. Results Of the 30 patients, 11 children had surgery in the first 3 months of life (1 ...
Outcome and recurrence patterns of TNBC patients in the general female population are currently reported to be less favorable than those of non-TNBC patients, with a survival rate as low as that of HER2-positive patients in the pre-trastuzumab era (12). Early tumor detection and the evolution to more effective treatment protocols may be crucial factors to improve the outcome of TNBC patients in high-risk women entered into an intensive annual multimodal screening started at early age. Here we comparatively evaluated phenotype features, treatment options, and survival rates of patients at high genetic-familial breast cancer risk found to be affected with either TNBCs or non-TNBCs during the HIBCRIT-1 study (18), starting from 25 years of age.. Relevant reasons prompted this study. First, more aggressive characteristics and poorer outcome of TNBCs have already been demonstrated by population-based analyses of cancer registries and retrospective studies on hospital-based patient cohorts (10, 11, ...
Leading AML expert Dr. Uma Borate goes back to the basics to explain how AML presents itself in the body and the recommended testing at diagnosis. Watch now to learn more.
Study Flashcards On Pediatric Case files at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Retrospective study of cholangiocarcinomas diagnosed in the hospital of Fuenlabrada in the period 2006-2016, Losada B, Gutierrez D, Juez I, Pantin MC, Anton B, Guerra JA, De Torre
Immunovia announces that the large retrospective autoimmune disease study, performed in collaboration with Lund Universitys IDEA Centre has been finalized.
CHANDLER, Ariz., Aug. 28, 2013 /PRNewswire/ -- Vomaris Releases New Retrospective Study Conclusions. Procelleras® Microcurrent Technology Associated With...
Mortality rates for many types of cancer in the U.S. are markedly higher among men than women, a large retrospective study found.
DUBLIN, IRELAND--(Marketwired - Oct 5, 2015) - Theravance Biopharma, Inc. (NASDAQ: TBPH) (Theravance Biopharma or the Company) today announced that data from studies of VIBATIV® (telavancin) will be presented at IDWeek™ 2015, being held in San Diego, CA, on October 7 - 11, 2015. New data from multiple retrospective clinical...
We find that rating a consumption experience (vs. not rating it) leads to the polarization of retrospective evaluation of that experience (i.e., positive experiences become more positive, negative experiences become more negative). We propose and find support for an exemplar memory account of this polarizing effect across four longitudinal studies. ...
In this retrospective review we comprehensively evaluated the EGFR mutation standing of people with adenocarcinoma who experienced been through operation and
Clinical charts and treatment protocols for numerous therapeutic diseases and disorders such as cardiovascular, oncology, neurological and many more. Download our FREE app now.
U.S. House Majority Whip Steve Scalise is still in serious condition but his health continues to show improvement, according to a statement from the MedStar Washington Hospital Center. Scalise, 51, had another...
The idea that cefepime could be neurotoxic has been documented in a number of case reports that temporally associated its use-and its discontinuation-with the appearance and then resolution of alterations in consciousness, or most concerningly with seizure activity. This was described particularly, although not exclusively, among the renally impaired (Jallon 2000, Chatellier 2002, Lam 2006, Fernandez-Torre 2006, Kim 2013).. However, the only large-ish study was by Fugate et al in 2013, reporting their experiences from the Mayo Clinic. In a retrospective chart review enrolling everyone who received 3+ days of cefepime in their ICU over a three-year period, they asked a panel of experts (with a modified Delphi format, aka "what do yall think?") whether the patient had experienced any neurotoxicity attributable to their cefepime. This was based upon temporal association of CNS derangement with both initiation and termination of the therapy, with no other plausible cause appreciated; notably, if ...
ACUR Share Price - Acura Pharmaceuticals, Inc. NASDAQ USA Technical Analysis, Target, Important Levels, Latest News, Interactive Charts.
Written by Prof. Jenn Final warning: These are RETROSPECTIVE reviews, so I will be discussing reveals, revolutions of cliffhangers, ends of plots, etc. If you are reading these reviews without having seen the eps, a) what is wrong with you?? Go watch them now! and b) these reviews are not for you till youve seen…
Methods. A total of 203 patients were selected for the current study. Malignancies prior to AAV diagnosis were identified using a nationwide pathology database, and their occurrence was verified by reviewing the medical files of 145 patients (71.4%). The malignancy incidence was compared to the general population by calculation of standardized incidence ratios (SIR), matching for sex, age, and time period. SIR were calculated for 2 intervals: , 2 years and ≥ 2 years prior to AAV diagnosis. Separate analyses were performed for GPA and MPA. ...
As of 1st November 2013, General Practitioners have access to bulk-billed MRI services for patients 16 years an over for a small range of clinically appropriate indications.  This is in addition to the GP access to paediatric MRI introduced in ...
The standard deviation is a standardized variance (ie the square root of the variance to brings the units back to the unit of the distribution because the variance is squared in order to get rid of a zero sum). ,MATH, \begin{array}{rrl} \text{Standard Deviation (SD)} & = & \sqrt{\href{variance}{Variance}} \\ & = & \sqrt{\frac{\displaystyle \href{Deviation Score}{\text{Sum of Squared (SS)}}}{\displaystyle \href{sample_size}{N}}} \\ & = & \sqrt{\frac{\displaystyle \sum_{i=1}^{\href{sample_size}{N}}{(\href{Residual}{\text{Residual}})^2}}{\displaystyle \href{sample_size}{N}}} \\ & = & \sqrt{\frac{\displaystyle \sum_{i=1}^{\href{sample_size}{N}}{(\href{raw_score}{X}_i- \href{mean}{\bar{X}})^2}}{\displaystyle \href{sample_size}{N}}} \\ \end{array} ,/MATH, ...
Lorenzo Lorenzo-Luaces, Robert J. DeRubeis, Annemieke van Straten, Bea Tiemens, A prognostic index (PI) as a moderator of outcomes in the treatment of depression: A proof of concept combining multiple variables to inform risk-stratified stepped care models, Journal of Affective Disorders, 2017, 213, ...
In the past, one of the biggest challenges non-neurologist or/and non-movement disorders physicians have faced in diagnosing PD has been the lack of uniformity in disease presentation. While variability in response to treatment has been a challenge at times for those of us in the field of Parkinsons disease. Although, no two individuals are ever really alike in the. ...
|p|Bringing together the work of over eighty leading academics and researchers worldwide to produce the definitive reference and research tool for the social sc
My sister had a transplant 17 years ago and now the new kidney is in failure and she has only 20% function they say she will be on dialysis soon. Her health is failing and she has lost so much weight. If you also have the doubt, please read
This report shows the number of reported cases of communicable diseasess by year for ten-year periods. Utah Bureau of Epidemiology.
Who an ultrasound during pregnancy is for, we will do our best to answer your questions and minimise your anxiety. The most common location for an..
Сайт Государственного автономного учреждения здравоохранения Межрегиональный клинико-диагностический центр (ГАУЗ МКДЦ), расположенного в РТ, г.Казань, ул. Карбышева д.12а.
If you utilize TNF blockers which include HUMIRA your chance of finding two kinds of skin most cancers may well increase (basal mobile most cancers and address squamous cell most cancers of your pores and skin). Most of these most cancers are usually not existence-threatening if treated. Notify your medical professional In case you have a bump or open sore that doesnt mend ...
Its also not overly harmful Regardless of staying an oral steroid, it doesnt create lots of Negative effects in the slightest degree, and is comparatively moderate around the pure endocrine method (for just a steroid, that is certainly). Youre not likely to get A lot, if any bodyweight from Anavar, but That which you do gain is going to be very good wanting muscle, and minor if any pounds obtain in how of h2o ...
twenty five] A random influence might be existing in both of those roles, but the two roles are read more pretty distinctive. There is not any motive to Consider the analysis model and info-technology system (product) are very similar in variety, but a lot of sub-fields of figures have formulated the pattern of assuming, for principle and simulations, that the data-technology system (design) is just like the analysis model we elect (or want Some others to select). Like a hypothesized mechanisms for creating the data, the random effect design for meta-analysis is silly and it is more suitable to think about this product for a superficial description and some thing we elect as an analytical Software - but this choice for meta-analysis may not function go to this site since the study results are a fixed attribute of the respective meta-analysis plus the probability distribution is just a descriptive Instrument.[twenty five ...
STUDY DESIGN.A retrospective cohort study. OBJECTIVES.The aim of this study was to evaluate radiographic and patient-reported outcomes at minimum 2 years after ...
... - Basic statistics and maths concepts and examples covering individual series, discrete series, continuous series in simple and easy steps
Despair, exhaustion, and sensation very Unwell you can try here like I had been intending to vomit for the few hours just after ingesting the methylb12. It took a couple of week in addition to a half for all those signs or symptoms to diminish. How could methylb12 trigger those symptoms? Overmethylation? Detox? These signs struck me as currently being fairly severe for overmethylation. I felt like I was undertaking fairly damn very well about the four hundred mcg five mthf. Any help could well be A lot appreciated ...
An average, or common case, is frequently not the richest in information and facts. In clarifying traces of background and causation it is more practical to pick topics which offer a fascinating, unconventional or especially revealing list of instances. A case choice that is based on representativeness will rarely be able to develop these kinds of insights. When picking out a case to get a case study, researchers will hence use facts-oriented sampling, as opposed to random sampling.[7] Outlier cases (that is definitely, Individuals that happen to be Excessive, deviant or atypical) expose more details than the possibly agent case ...
If His Excellency the Presidents approval is rendered for the surgery / treatment prior to such surgery is done or treatment administered the letter of guaranty is made available to the hospital or the Institution concerned on the exact date of admission to the hospital is provided to the Presidents Fund.. In the case of cancer patients the letter of guaranty could be obtained 30 days after the patient is admitted to the hospital for treatment whereas in the case of other patients the letter of guaranty could be obtained 14 days before the surgery is done.. The guaranty letter can be obtained for the treatments of cancer patients 30 days prior to the admission to the hospital whereas for the others 14 days prior to the surgery.. ...
We have been extremely impressed with all your ability to navigate your way through this type of system, and felt you were quite supportive as part of your initiatives to have us over the line. You did, thanks, and we have been delighted with the end result. In spite of refinancing for any greater sum, our repayments are actually decreased than just before, and We have now "home to move" and monetary peace of mind that our circumstance is managed inside of a financially audio manner ...