Raynaud phenomenon is known to occur in around 10% of the healthy female population and in around 5% of men. In the vast majority of cases, the blood vessels show no evidence of damage. In this case - so called Primary Raynaud phenomenon - the issue appears to be exaggerated spasm of healthy blood vessels.. Raynaud phenomenon is also the most common first symptom of scleroderma and is an important feature in other rheumatologic illnesses such as lupus. In this situation, the blood vessels are damaged and the opening for blood flow is much reduced. Raynaud episodes in scleroderma may reflect normal blood vessel constriction in response to cold superimposed on the narrow plumbing.. Blood flow to the fingers in normal health is around 40 times as much as is needed for oxygen supply and tissue nutrition. When the body is hot, blood flow increases to the hands so as to dissipate heat. This is much like a dog panting on a hot day. Conversely, when the body is cold, it is normal to reduce blood flow to ...
Plaquenil For RaynaudS Syndrome. anyone been prescribed Hydroxychloroquine for raynauds anyone been prescribed Hydroxychloroquine for raynauds I take hydroxychloroquine fir sjogrens syndrome Im not sure that it has helped with the Raynauds, Plaquenil and Raynauds disease - Reviews - TreatoPlaquenil and Raynauds disease . but with him it is a primary raynauds, I would say that you might have been suffering from Raynauds Syndrome and Plaquenil Raynauds PhenomenonInformation for patients with Raynauds phenomenon: what it is, common causes, getting diagnosed, treatment options, and tips for living with the condition.Our Top 5 Tips for Raynauds buy cialis Syndrome - Conquering SjogrensI started having symptoms of Raynauds Syndrome when I was very young. I was diagnosed with Sjogrens 2 and 1/2 years ago. I am taking Plaquenil and the About Raynauds Disease - Lupus Resource CenterRaynauds is a common overlapping condition with lupus viagra alternatives that can cause numbness in the About ...
Plaquenil For RaynaudS Syndrome. anyone been prescribed Hydroxychloroquine for raynauds anyone been prescribed Hydroxychloroquine for raynauds I take hydroxychloroquine fir sjogrens syndrome Im not sure that it has helped with the Raynauds, Plaquenil and Raynauds disease - Reviews - TreatoPlaquenil and Raynauds disease . but with him it is a primary raynauds, I would say that you might have been suffering from Raynauds Syndrome and Plaquenil Raynauds PhenomenonInformation for patients with Raynauds phenomenon: what it is, common causes, getting diagnosed, treatment options, and tips for living with the condition.Our Top 5 Tips for Raynauds buy cialis Syndrome - Conquering SjogrensI started having symptoms of Raynauds Syndrome when I was very young. I was diagnosed with Sjogrens 2 and 1/2 years ago. I am taking Plaquenil and the About Raynauds Disease - Lupus Resource CenterRaynauds is a common overlapping condition with lupus viagra alternatives that can cause numbness in the About ...
TY - JOUR. T1 - Efficacy of Rho kinase inhibitor fasudil in secondary Raynauds phenomenon. AU - Fava, Andrea. AU - Wung, Peter K.. AU - Wigley, Fredrick M.. AU - Hummers, Laura K.. AU - Daya, Natalie R.. AU - Ghazarian, Sharon R.. AU - Boin, Francesco. PY - 2012/6/1. Y1 - 2012/6/1. N2 - Objective: The RhoA/Rho kinase pathway plays a pivotal role in cold-induced vasoconstriction, vascular smooth muscle cells function, and vascular homeostasis. This study evaluates the efficacy of fasudil, a RhoA/Rho kinase inhibitor, to reverse cold-induced vasospasm in patients with Raynauds phenomenon (RP) secondary to systemic sclerosis (SSc; scleroderma). Methods: This is a single-center, double-blind, placebo-controlled, randomized, 3-period crossover study of oral fasudil (40 mg or 80 mg) or placebo administered 2 hours before a standardized cold challenge. The fall in skin temperature after the cold challenge and time to recover 50% and 70% of prechallenge digital skin temperature were used as primary ...
TY - JOUR. T1 - Management of Raynaud Phenomenon and Digital Ulcers in Scleroderma. AU - Cappelli, Laura. AU - Wigley, Fredrick M.. N1 - Copyright: Copyright 2016 Elsevier B.V., All rights reserved.. PY - 2015/8/1. Y1 - 2015/8/1. KW - Calcium channel blocker. KW - Digital ischemia. KW - Digital ulcer. KW - Prostacyclin. KW - Raynaud phenomenon. KW - Scleroderma. KW - Thermoregulatory vessels. UR - http://www.scopus.com/inward/record.url?scp=84937967687&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84937967687&partnerID=8YFLogxK. U2 - 10.1016/j.rdc.2015.04.005. DO - 10.1016/j.rdc.2015.04.005. M3 - Review article. C2 - 26210127. AN - SCOPUS:84937967687. VL - 41. SP - 419. EP - 438. JO - Rheumatic Disease Clinics of North America. JF - Rheumatic Disease Clinics of North America. SN - 0889-857X. IS - 3. ER - ...
Reversible vasospasm of the extremities occurs as an isolated symptom in the absence of underlying disease (primary Raynaud phenomenon) or in association with other disorders (secondary Raynaud phenomenon). It has been reported that Raynaud phenomenon is associated with connective tissue diseases, but the frequency and types of diseases that eventually develop are not well established. Spencer-Green conducted a systematic literature search to assess the rates and predictors of transition to secondary disease after a primary diagnosis of Raynaud phenomenon.. A total of 639 patients with primary Raynaud phenomenon were identified from 10 studies. The average length of study follow-up was four years. The average duration of Raynaud phenomenon in the study subjects was 12.3 years. During follow-up, 12.6 percent (81 patients) developed a secondary disorder. Eighty of these cases were connective tissue diseases. Two thirds of the cases of connective tissue disease were attributed to systemic ...
Raynauds Syndrome. Raynauds phenomenon. Raynauds disease. Cold hands? Cold fingers? Cold feet? Cold toes? The Haven Healing Centre. Complementary Therapy in Bristol, Bath and Surrounding Area. Philip Chave, Healer and Therapist
Raynauds Disease, Raynauds Syndrome, Raynauds Phenomenon all refer to a vascualar condition affecting the feet and hands. Podiatrist Brisbane
Diagnosis and conservative treatment of raynauds syndrome (Raynaud disease ) (costs for program #151501) ✔ University Hospital Münster ✔ Department of Gerneral Internal Medicine, Nephrology, Hypertension Diseases and Rheumatology (Medical Department D) ✔ BookingHealth.com
Diagnosis of raynauds syndrome (Raynaud disease ) (costs for program #242505) ✔ University Hospital Hamburg-Eppendorf ✔ Department of Pediatrics ✔ BookingHealth.com
Raynauds disease is an affliction caused by the constriction of blood vessels, usually in response to an external stimulus, particularly in the fingers and toes. This phenomenon results in numbing and discomfort of those appendages.. There are two forms of Raynauds disease. Primary Raynauds occurs on its own, most often in women. It is also the most common form of the condition. Secondary Raynauds is less common and occurs in conjunction with another health issue that causes the reduction of blood flow to the extremities.. Causes of Raynauds disease vary, but is generally associated with the bodys overreaction to cold or stress. Secondary Raynauds (also called Raynauds phenomenon) is more serious and can result in permanent tissue damage. It can be triggered by other health conditions including coronary artery disease, connective tissue conditions (such as lupus or rheumatoid arthritis), or carpal tunnel syndrome. Certain medications have also been linked to the onset of Raynauds ...
It is the intention of this protocol to study, in a controlled manner, the response of fingers of patients with Raynauds phenomenon to two dosage strengths of a fast acting topical formulation of Nitroglycerin, MQX-503. Patients may have moderate to severe primary Raynauds phenomenon or Raynauds phenomenon secondary to autoimmune diseases such as scleroderma.. Quantitative changes in blood flow in the fingers of the non-dominant hand will be measured after the clinical induction of constriction of blood vessels by exposure to local cold temperatures. Secondarily, the quantitative reduction in skin temperature recovery time and symptoms of pain, tingling and numbness associated with Raynauds phenomenon will be evaluated using a patient hand symptom analog assessment score. The frequency and severity of adverse events associated with MQX-503 will be assessed. ...
This page includes the following topics and synonyms: Raynauds Phenomenon, Raynauds Syndrome, Raynaud Disease, Raynaud Phenomenon, Raynaud Syndrome.
Q: While waiting at the bus stop, my 13-year-old daughters fingers got cold and turned blue, with a clear line between the blue and normal parts. I am going to take her to the pediatrician next week to have her checked, but I wanted to know what this could be.A: The description you give sounds a lot like pediatric Raynaud phenomenon (RP), a transient constriction of the small arteries that can compromise the blood flow to the fingers (less commonly the toes or even the ears), typically
Q: While waiting at the bus stop, my 13-year-old daughters fingers got cold and turned blue, with a clear line between the blue and normal parts. I am going to take her to the pediatrician next week to have her checked, but I wanted to know what this could be.A: The description you give sounds a lot like pediatric Raynaud phenomenon (RP), a transient constriction of the small arteries that can compromise the blood flow to the fingers (less commonly the toes or even the ears), typically
Q: While waiting at the bus stop, my 13-year-old daughters fingers got cold and turned blue, with a clear line between the blue and normal parts. I am going to take her to the pediatrician next week to have her checked, but I wanted to know what this could be.A: The description you give sounds a lot like pediatric Raynaud phenomenon (RP), a transient constriction of the small arteries that can compromise the blood flow to the fingers (less commonly the toes or even the ears), typically
RP is an exaggerated vascular response to cold temperature or emotional stress, primarily seen in young women. It is classified into primary or idiopathic without underlying disease and secondary when it is related to various medical problems.1,2 Clinical criteria are used to distinguish between patients with uncomplicated or primary RP, and those with secondary RP. The suggested criteria for primary RP are symmetric attacks; the absence of tissue necrosis, ulceration or gangrene; the absence of a secondary cause on the basis of a patients history and general physical examination; normal nailfold capillaries; a negative test for antinuclear antibody; and a normal erythrocyte sedimentation rate.2,3 The most common diseases associated with secondary RP are scleroderma, mixed connective tissue disease, systemic lupus erythematosus, occlusive vascular disease, drug effects, haematological abnormalities, and use of vibrating tools.1,3 Primary RP occasionally evolves into a connective tissue disease, ...
Definition of Raynaud's disease in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Raynaud's disease? Meaning of Raynaud's disease as a legal term. What does Raynaud's disease mean in law?
RP is classified into two categories: primary and secondary. Primary RP are vasospastic attacks precipitated by cold temperatures or emotional stress. Primary RP, which occurs in the absence of an identifiable disease, is most common in otherwise healthy females between 15 and 30 years of age. A family history of first-degree family members is reported in about 30% of cases. These attacks usually occur symmetrically and bilaterally in the hands. There is no underlying sign of tissue necrosis or gangrene (eg, digital pitting) and the underlying vasculature is normal. Nailfold capillary microscopy (see below) and physical examination findings are normal. If a patient meets criteria for primary RP and no new symptoms develop over 2 years of follow-up, the development of secondary disease is unlikely. The finding of abnormal nailfold capillaries on microscopy or specific autoantibodies are strong predictors of secondary RP due to an underlying rheumatologic disease. ...
Raynaud Syndrome Symptom Checker: Possible causes include Raynaud Disease. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Raynauds disease, syndrome or phenomenon, whether primary or secondary, is characterized by extreme coldness in the hands or feet, the fingers or toes becoming white and numb. The color may change to blue and finally red, as the blood returns to the tissues. This can take from several minutes to many hours, and can be extremely painful. It may also affect the ears and nose.. Why Raynauds phenomenon occurs is not well understood. Usually, the body conserves heat by reducing blood circulation to the extremities, particularly the hands and feet. This response uses a complex system of nerves and muscles to control blood flow through the smallest blood vessels in the skin. In people with Raynauds phenomenon, this control system becomes too sensitive to cold and greatly reduces blood flow in the fingers. Damage to either the muscles or nerves that control blood flow may be the cause of Raynauds phenomenon.. Treatment may vary according to the severity of the symptoms. In mild cases it may be ...
NEXMED TO DISCUSS P2/3 PROTOCOL FOR NEXACT® -BASED ALPROSTADIL TREATMENT FOR RAYNAUDS SYNDROME WITH THE FDA San Diego--(BUSINESS WIRE)-- NexMed, Inc. (Nasdaq: NEXM), a specialty CRO with a
Qué es el fenómeno de Raynaud? El fenómeno de Raynaud es una enfermedad que afecta los vasos sanguíneos. Si usted tiene el fenómeno de Raynaud, tiene periodos llamados episodios cuando el cuerpo no envía suficiente sangre a las manos y los pies. Los episodios generalmente ocurren cuando la persona tiene frío o se siente estresada. Durante un episodio, los dedos de las manos y los pies pueden sentirse muy fríos o entumecidos. El fenómeno de Raynaud también se conoce como la enfermedad de Raynaud o el síndrome de Raynaud ...
Qué es el fenómeno de Raynaud? El fenómeno de Raynaud es una enfermedad que afecta los vasos sanguíneos. Si usted tiene el fenómeno de Raynaud, tiene periodos llamados episodios cuando el cuerpo no envía suficiente sangre a las manos y los pies. Los episodios generalmente ocurren cuando la persona tiene frío o se siente estresada. Durante un episodio, los dedos de las manos y los pies pueden sentirse muy fríos o entumecidos. El fenómeno de Raynaud también se conoce como la enfermedad de Raynaud o el síndrome de Raynaud ...
Dear Editor,. Congratulations Canadian Family Physician and Dr Ran D. Goldman for the Child Health Update on Raynauds phenomenon (RP) [1]. I would like to point to a new study in childhood on this underrated functional vascular disease.. The pediatric research group of Gorski et al from Poland examined with the help of nail fold capillaroscopy and blood tests 66 patients with RG (34 undifferentiated RP and 32 secondary RP) aged 6-19 years and a control group with 20 healthy children [2]. Compared to the control group, significantly higher concentrations of endothelin-1 (p = 0.0134), sE-selectin and high-sensitivity C-reactive protein (hsCRP: p , 0.001) were found in the patients with RG, as well as a lower high-density lipoprotein cholesterol concentration in the lipid profile (p = 0.001). The group over 15 years also had higher levels of low-density lipoprotein fraction and triglyceride. As the analysis of multiple linear regression showed, among the capillaroscopic parameters, the more ...
Raynauds disease comes in multiple forms, with different causes and treatments. Learn about the difference between primary and secondary Raynauds disease.
Testing fo Raynauds disease and Raynauds phenomenon at an ACR Accredited Vascular Lab in Buffalo Niagara at the Vein Treatment Center call 716-839-3638
Look for causes. When a patient has raynauds phenomenon (vasospasm in the fingers and toes), his doctors will look for the common causes such as autoimmune disorders, drug side effects, hormonal imbalances, etc... If no medical condition is found that is causing the symptoms, then the disorder is called raynauds disease. If an underlying condition is found, then the disorder is called raynauds syndrome ...
Once a doctor has diagnosed Raynauds phenomenon, there are several simple, effective methods to help manage the symptoms. While there is no known cure for Raynauds phenomenon, people with the disease are usually able to manage their symptoms with medications and. behavior modification.. There are a number of strategies to treat the symptoms of Raynauds phenomenon. Most importantly, protecting the core body (hat, scarf, layered clothes) as well as the hand. s and. feet from cold temperatures will help prevent discomfort. Wearing gloves and. heavy socks in winter is a simple protection strategy. Some people with Raynauds phenomenon even find it helpful to wear cotton gloves or oven mitts reach into freezers, to protect sensitive hand. s and. reduce the risk of vasospasms.. People with Raynauds phenomenon should not smoke or be exposed to second-hand. smoke, as smoking restricts blood vessels and. can exacerbate the condition.. About the research. The research was conducted by the University ...
Results. In the group of patients with Raynauds phenomenon mean serum concentration of ET-1, TNF-α, PF-4, and vWF was significantly greater than in the healthy group. In contrast, serum IL-6 and IL-6sR concentrations did not differ significantly between the diseased and healthy groups. In a subgroup of Raynauds phenomenon patients showing particularly high concentration of serum ET-1 (twice as much as mean control concentration), the increase in IL-6, IL-6sR, vWF and c-ANCA concentration exhibited statistical significance in comparison with patients with lower serum ET-1 concentration. The vWF concentration exhibited positive correlation with time interval between the occurrence of clinical symptoms and serum ANA antibodies concentration. The increase in ET-1 synthesis in Raynauds phenomenon patients is dependent on the increase in IL-6 level and c-ANCA antibodies level ...
The condition can cause pain within the affected extremities, discoloration (paleness), and sensations of cold and/or numbness. This can often be distressing to those who are undiagnosed, and sometimes it can be obstructive. If someone with Raynauds is placed into a cold climate, it could potentially become dangerous. When exposed to cold temperatures, the blood supply to the fingers or toes, and in some cases the nose or earlobes, is markedly reduced; the skin turns pale or white (called pallor) and becomes cold and numb. These events are episodic, and when the episode subsides or the area is warmed, the blood flow returns, and the skin color first turns red (rubor), and then back to normal, often accompanied by swelling, tingling, and a painful pins and needles sensation. All three color changes are observed in classic Raynauds. However, not all patients see all of the aforementioned color changes in all episodes, especially in milder cases of the condition. Symptoms are thought to be due ...
To the editor: In connection with the article by Vogelzang and associates (1) on Raynauds phenomenon and its relation to vinblastine-bleomycin therapy, we wish to describe a new case.. A 41-year-old man with an embryonal carcinoma in the mediastinum developed Raynauds phenomenon with distal necrosis in the third month of treatment with vinblastine, bleomycin, and cisplatin (2). An arteriogram showed multiple arterial occlusions; the findings of a rheumatologic diagnostic study (including cryoglobulins) were negative. He smoked, but had never before had Raynaud manifestations. The severe pain was relieved only with intra-arterial vasodilators.. This case calls attention to vinblastine-bleomycin as a ...
Raynaud and Seiver Disease affect the feet, but in different ways. Raynauds Disease causes spasms, while Seivers Disease can mimic Achilles tendonitis.
Raynauds disease is a condition characterized by periods of time when the fingers or toes (sometimes nose and ears) turn color and go numb due to an interruption of blood flow to the extremities due to a vasospasm (Mayo Clinic). Often they will turn white, sometimes blue, and then red when blood flow returns. Typically people with Reynauds feel numbness in the affected areas during an episode and may experience pain when blood flow returns. The most common cause of a flare up is exposure to cold, though sometimes people experience the phenomenon during times of stress.. Raynauds may be primary (meaning it isnt due to an underlying cause) or secondary (the phenomenon is due to a condition such as nerve damage, carpal tunnel syndrome, rheumatoid arthritis or lupus.). According to Mayo Clinic, some medications can also cause the Raynauds phenomenon.. The majority of people who experience Raynauds symptoms do not report it to a physician, (Raynauds.org) but it is worth noting at your next ...
The term scleroderma is derived from the Greek words skleros (hard or indurated) and derma (skin) and it is used to describe a disease characterized by progressive skin hardening and induration. Hippocrates first described this condition as thickened skin.
Authors: NEVZAT GÖZEL, AHMET KARATAŞ, MELTEM YARDIM, MESUDE SEDA AYDOĞDU, RAMAZAN ULU, FATİH DEMİRCAN, FARUK KILINÇ, BURAK ÖZ, EMİR DÖNDER, SÜLEYMAN AYDIN, SÜLEYMAN SERDAR KOCA Abstract: Background/aim: The pathogenesis of Raynauds phenomenon (RP) has not yet been fully elucidated. RP is characterized by exaggerated cold-induced vasoconstriction. Urotensin II (UII) is a potent vasoconstrictor. The aim of the present study was to evaluate plasma UII levels in both primary RP and secondary RP associated with systemic sclerosis (SSc).Materials and methods: Fifteen patients with primary RP, 30 patients with RP secondary to SSc, and 30 healthy controls (HC) were included in the study. Raynaud condition scores (RCS) were determined in the primary RP and SSc groups. Modified Rodnan skin score (MRSS) was determined for the SSc patients. Plasma UII level was analyzed by the ELISA method. Results: When compared to the HC group, plasma UII level was lower in the secondary RP group, but not in ...
Raynauds phenomenon (RP) is a vasospastic disorder characterized by episodic color changes of blanching, cyanosis, and hyperemia in response to cold and/or emotional stress. Although most typically noted in the fingers, the circulation of the toes, ears, nose and tongue is also frequently affected. Population studies have shown that RP in adults is more common in women than men, with prevalence estimates ranging from 4% to 30%. Geographic variations in the prevalence reflect differences in climate. RP may be a primary or a secondary process. LeRoy and Medsger suggested criteria for primary RP: symmetric attacks, the absence of tissue necrosis, ulceration or gangrene, the absence of a secondary cause, negative antinuclear antibodies, normal nailfold capillaroscopy and a normal erythrocyte sedimentation rate. Secondary RP is characterized by an age of onset of more than 30 years, painful and asymmetric attacks, ischemic skin lesions, positive autoautoantibodies, capillaroscopic abnormalities ...
OBJECTIVES--To determine whether the active 25 kDa form of the fibrogenic cytokine transforming growth factor beta (TGF beta) can be detected in plasma from patients with systemic sclerosis and to examine the relationship between plasma TGF beta and clinical markers of disease severity and serum concentrations of the aminoterminal peptide of type III procollagen (PIIINP) (a laboratory marker of the fibrotic process). METHODS--A cross sectional study was made of 39 patients with systemic sclerosis (11 diffuse and 28 limited), nine patients with primary Raynauds disease and 60 healthy controls. TGF beta 1 and TGF beta 2 were measured by enzyme linked immunosorbent assay (ELISA) (sensitivity 100 pg/ml) and PIIINP by radioimmunoassay. RESULTS--TGF beta 1 was detected in plasma from six of 39 patients with systemic sclerosis but not in any patient with primary Raynauds disease or healthy controls. TGF beta 2 was not detected in plasma from patients or controls. No clear relationship was ...
Raynauds Disease is a disorder that affects the hands and feet. It is caused by contraction of the smooth muscles controlling the small arteries supplying circulation into the hands and feet. This contraction, called a vasospasm, makes the arteries so small that they restrict blood flow. Exposure to cold temperature can often bring on a vasospasm.. Raynauds Disease has no known cause and is most common in young women. Staying warm and exercising regularly to maintain healthy blood circulation throughout the body can help offset the disease.. ...
Raynaud's syndrome is a common in fibromyalgia and chronic fatigue syndrome. Learn about this cause of extremely cold hands and feet.
Systemic sclerosis (also known as scleroderma) is a rare multi-system connective tissue disease. It is characterised by excessive collagen deposition (leading to fibrosis), vascular abnormality and immune dysfunction.. Raynauds phenomenon (episodic colour changes of the fingers, usually in response to cold exposure) is very common. It is a key feature of systemic sclerosis but, for most people, it occurs in the absence of any underlying condition in which case it is termed primary Raynauds phenomenon.. ...
Raynauds phenomenon of the nipple was described first in 1970 and Lawlor-Smith and Lawlor-Smith reported 5 cases. There are numerous references to Raynauds phenomenon while breastfeeding in the lactation literature and on the Internet, but this is the first report in the pediatric literature. Symptoms common to all 12 cases include extreme nipple pain, blanching of the nipple with breastfeeding followed by redness or bluish coloration accompanied by intense throbbing pain, and precipitation of symptoms with environmental cold temperature. The nipple pain is so severe that it causes most women to stop breastfeeding. One of our mothers described her pain as a vice clamped on my nipples.. Poor positioning and poor attachment or latch may cause blanching of the nipple and pain during breastfeeding; thus, it is important to seek additional symptoms (such as precipitation by cold stimulus, occurrence of symptoms during pregnancy or when not breastfeeding, and biphasic or triphasic color changes) ...
Raynauds phenomenon of the nipple was described first in 1970 and Lawlor-Smith and Lawlor-Smith reported 5 cases. There are numerous references to Raynauds phenomenon while breastfeeding in the lactation literature and on the Internet, but this is the first report in the pediatric literature. Symptoms common to all 12 cases include extreme nipple pain, blanching of the nipple with breastfeeding followed by redness or bluish coloration accompanied by intense throbbing pain, and precipitation of symptoms with environmental cold temperature. The nipple pain is so severe that it causes most women to stop breastfeeding. One of our mothers described her pain as a vice clamped on my nipples.. Poor positioning and poor attachment or latch may cause blanching of the nipple and pain during breastfeeding; thus, it is important to seek additional symptoms (such as precipitation by cold stimulus, occurrence of symptoms during pregnancy or when not breastfeeding, and biphasic or triphasic color changes) ...
Looking for online definition of Raynaud syndrome in the Medical Dictionary? Raynaud syndrome explanation free. What is Raynaud syndrome? Meaning of Raynaud syndrome medical term. What does Raynaud syndrome mean?
Looking for online definition of Raynaud in the Medical Dictionary? Raynaud explanation free. What is Raynaud? Meaning of Raynaud medical term. What does Raynaud mean?
Vibration White Finger or VWF is caused by the vibrations from power tools such as drills, chainsaws or hammers. Using such tools is common practice in many construction and industry working environments.. If you are suffering from vibration white finger as a result of your work, you may be entitled to compensation.. Vibration white finger can result in horrible symptoms, including constant pain in that hands which hugely reduce your quality of life, and it can stop you working for good in the job that you love. If youre worried about the financial implications of vibration white finger, you shouldnt hesitate to make a vibration white finger claim for compensation.. Your employer has a duty to protect you from injuries such as VWF and should have trained you accordingly to make you aware of the dangers and threats that are posed in these situations. If they have failed to do so, then they become liable for compensation claims against them.. If you have not been protected from VWF then Contact ...
Considering a prevalence of 5-10% in the general population, there is still a place and probably a need for the development of new treatment concepts. Ginkgo biloba has shown to have anti-oxidative and anti-platelet activities. In a small placebo controlled trial in patients with the Raynaud´s phenomenon promising results for the Ginkgo biloba extract were shown. EGb 761® is known to be safe and well tolerated. Based on the above considerations, EGb 761® may be an effective treatment for Raynaud´s phenomenon.. Aim: To determine the efficacy and safety of EGb 761® in patients with Raynaud´s phenomenon on the frequency, duration, and severity of vasospastic attacks compared to placebo. ...
If you have suffered an VWF as a result of operating vibrating machinery you may be entitled to vibration white finger compensation and you should contact our solicitors** in Bolton to obtain further information.. Vibration white finger compensation may be available if you suffer from symptoms such as numbing of the fingers, throbbing in the fingers, changes to your sense of touch, lack of strength in the fingers or the loss of colour in fingers (which normally occurs in cold weather).. The cause of injury normally relates to use of vibrating machinery such as large drills, chainsaws, trimmers, concrete breakers or other types of pneumatic drilling systems. This type of injury normally arises after a long period of use of such machinery, and may well not be immediately noticeable.. In order to assess vibration white finger compensation, a number of factors will be assessed. These include discussing the working arrangements which may have caused the injury, the length of time you may have been ...
Although an early capillaroscopic pattern can occur in patients who have suffered from Raynauds phenomenon for many years, the term early is used because this pattern tends to occur initially; it also can be observed in patients with shorter disease duration than in those with active or late patterns. However, it must be recognized that capillaroscopic patterns are descriptive and that there is inevitable overlap between patterns. The differences between the pattern in SSc and the normal pattern of healthy subjects or patients with benign primary Raynauds phenomenon can be readily observed (see Figure 12).. The development of robust scoring systems to quantify the microvascular change is essential to the performance longitudinal studies. For this reason, a practical system to score these capillaroscopic alterations in patients with SSc has been recently proposed and validated.7,8 Interestingly, in studies on clinical findings over time, about 15%-20% of primary Raynauds phenomenon are ...
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Monday, October 1, 2012 Vibration-induced white finger disease (VWF) is caused by continued use of vibrating hand held machinery (high frequency vibration ,50 Hz), and affects tens of thousands of people. New research published in BioMed Centrals open access journal Clinical Epigenetics finds that people with a genetic polymorphism (A2191G) in sirtuin1 (SIRT1), a protein involved in the regulation of endothelial NOS (eNOS), are more likely to suffer from vibration-induced white finger disease.. VWF (also known as hand arm vibration syndrome (HAVS)) is a secondary form of Raynauds disease involving the blood vessels and nerves of arms, fingers and hands. Affected fingers feel stiff and cold and loose sensation for the duration of the attack, which can be very painful. Loss of sensation can make it difficult to carry out manual activities. Initially attacks are triggered by cold temperatures but as the disease progresses attacks can occur at any time.. Little is known about what causes the ...
There has been substantial controversy regarding the use of spinal cord stimulation in ischemic extremity disease. However, current information favors the use of this treatment in inoperable ischemic extremity disease. There have been a large number of prospective studies, as well as a systematic Cochrane Review, indicating the appropriateness of spinal cord stimulation in this scenario.5 However, the studies focus primarily on atherosclerotic vascular disease. Although the exact mechanism of action of spinal cord stimulation in ischemic extremity disease is still uncertain, it most certainly affects peripheral vasoconstriction and therefore should be effective in vasospastic disease, such as Raynauds Disease ...
Marco Sebastiani, Konstantinos Triantafyllias, Andreina Manfredi, Miguel Angel González-Gay, Natalia Palmou-Fontana, Giulia Cassone, Ulrich Drott, Christiane Delbrück, Jorge Rojas-Serrano, Chiara Bertolazzi, Laura Nuño, Margherita Giannini, Florenzo Iannone, Esther F. Vicente, Santos Castañeda, Albert Selva-OCallaghan, Ernesto Trallero Araguas, Giacomo Emmi, Annamaria Iuliano, Jutta Bauhammer, Nikolaus Miehle, Simone Parisi, Lorenzo Cavagna, Veronica Codullo, Carlomaurizio Montecucco, Francisco Javier Lopez-Longo, Julia Martínez-Barrio, Juan Carlos Nieto-González, Silvia Vichi, Marco Confalonieri, Paola Tomietto, Raoul Bergner, Alberto Sulli, Francesco Bonella, Federica Furini, Carlo Alberto Scirè, Alessandra Bortoluzzi, Christof Specker, Simone Barsotti, Rossella Neri, Marta Mosca, Marzia Caproni, Julia Weinmann-Menke, Andreas Schwarting, Vanessa Smith, Maurizio Cutolo and The American and European Network of Antisynthetase Syndrome Collaborative Group ...
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Vibration white finger primarily affects those who work in industries which require the use of power tools, such as concrete vibrators.
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We found a useful article by Anne Mawdsley, the Founder of the Raynauds and Scleroderma Association in the UK, that was published in the British Journal of Health Care Assistants. Its titled: Raynauds Phenomenon: What Can Be Done for Patients?. As its written by someone who has experienced Raynauds first-hand (most articles published in journals are authored by medical professionals), it does a good job of describing our symptoms and lifestyle issues. Heres a great quote: Many people have described the pain during a Raynauds phenomenon attack as being similar to having frostbite or having trapped your fingers in a car door. Not your usual frame of reference!. It also makes a good point of the fact that Raynauds attacks may be triggered by exposure to even a small change in temperature. We often associate the pain with absolute cold temperature thresholds, but stepping into a draft or moving from a colder air-conditioned building into a warmer temperature outdoors in summer months can ...
St. Marys College of Maryland (SMCM) anthropology students Melody Raynaud and Daniel Mehaffey have been selected as inaugural Undergraduate Research Fellows for the American Anthropological Association. Raynaud and Mehaffey are two of only six fellows selected from a nationwide pool of applicants that received the fellowship. Since receiving the fellowship from the American Anthropological Association, a first-year student, Colette Nortman, has joined the team in order to gain first hand ethnographic research experience.. Funded by the Center for Research on College-Workforce Transitions of the Wisconsin Center for Education Research at the University of Wisconsin, Madison, this program supports research projects that use ethnographic or mixed methods to address the question, how do anthropology majors prepare for life after college?. With mentor and professor of anthropology William Roberts, Raynaud and Mehaffey will focus their research on answering questions regarding students experiences ...
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List of causes of Proximal muscle weakness and Sensory symptoms and Sudden onset of Raynauds phenomenon, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Raynauds phenomenon may be helped by some supplements. Learn more about fish oil, Gingko biloba, and ginseng. ConsumerLabs answer explains.
Without Raynauds you cannot diagnose Scleroderma. I think it is completely unprofessional for your doctor to say you have this, or even suspect it - since hes not a rheumatologist. If you dont have Raynauds you dont have this... Something like 98% of those with Scleroderma have very severe Raynauds. Multiple people on this board have Raynauds, but were talking severe Raynauds where your fingers turn mutliple colors and you literally have to put them under warm water to get them back to normal ...
The peripheral circulation was studied in 19 lumberjacks and in 12 control subjects. Twelve of the lumberjacks were free from vascular symptoms and seven had vibration induced white finger (VWF). Using the strain-gauge plethysmographic technique, the digital circulation was examined at rest, during cooling of the upper body, and during heating of the upper body. At rest and during vasodilatation no significant differences were found between the lumberjacks and the controls. During reflexive vasoconstriction, digital blood flow in the upper body was more reduced in lumberjacks with VWF than in control subjects. Furthermore, digital blood pressure of the lumberjacks with VWF fell more than in the control group. The peripheral resistance also increased more, but this difference was not statistically significant. There was no evidence that the exaggerated vasoconstriction of VWF resulted from a narrowing of the lumen of arterioles due to hypertrophy of the vessel wall. The present findings suggest ...
www.MOLUNA.de Case Studies in Systemic Sclerosis [4185368] - A 35- Year Old Woman with Puffy Hands, Raynauds Phenomenon, & Positive Antinuclear Antibody Test.- A 30- Year Old Woman with Puffy Hands, Raynauds Phenomenon, & Carpal Tunnel Syndrome.- A 22- Year Old Woman with Raynauds Phenomenon But No Other Symptoms & No Abnormalities on Examination.- A Young Adult With
A 35-year-old white woman was seen in 1987 reporting recurrent arthralgias, rash, increased hair loss, and the Raynaud phenomena. Her physical examination showed a malar flush, the presence of herpes zoster along the lateral aspect of her abdomen, and synovitis of her wrists and ankles. Laboratory results included: a positive antinuclear antibody count (1:640 homogeneous), an erythrocyte sedimentation rate of 20 mm/h, a moderately positive double-stranded DNA, a normal C3, and a slightly low C4 ...
WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms Cold feet, Cold hands, Color change and Joint pain and including Carpal tunnel syndrome, Raynaud phenomenon and Cold exposure.
The Raynauds phenomenon is named after the French doctor who first wrote about in the 1850. There is Raynauds phenomenon or simply Raynauds is a disorder to the characterized by decreased blood flow usually to the fingers and less frequently to the ears, toes, nipples, knees, or nose. The Raynauds can occur alone or may occur with other diseases. The diseases most frequently by the associated with Raynauds are autoimmune or connective tissue diseases, among others, such as the followings are systemic lupus erythematous and scleroderma and CREST syndrome, Buergers disease, polymyositis, Sjogrens syndrome, occlusive vascular disease, rheumatoid arthritis, cryoglobulinemia. They are one theory links blood disorders to the characterized by increased platelets or red blood cells that may increase the blood thickness. The phenomenon of heart disease will be varying from one person to another person in the real world.. Risk Factor:. The risk of factor is anything that may be increases a persons ...
WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms Cold feet, Cold feet, Guarding or favoring joint and Joint instability and including Raynaud phenomenon, Osteoarthritis and ACL knee injury.
Anemia, neutropenia, or thrombocytopenia is due to bone marrow infiltration of plasma cells. Thrombosis and Raynaud phenomenon due to cryoglobulinemia may be present.
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HAVS condisitons are caused by regular exposure to high level vibration. Compactors are among the types of equipment most at risk of causing this injury.
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
This can often be linked to hearing loss as the tools used can also be extremely noisy. It is a vascular disorder causing impaired blood circulation and blanching (whitening) of the affected fingers and parts of the hand.
Authors: Ostojić, Predrag , Damjanov, Nemanja , Pavlov‐Dolijanovic, Slavica , Radunović, Goran Article Type: Research Article Abstract: Objective: To examine the difference in clinical signs of peripheral vasculopathy in patients (pts) with limited (lcSSc) and diffuse cutaneus systemic sclerosis (dcSSc). Patients and methods: Ninety one patients with systemic sclerosis (39 with lcSSc and 52 with dcSSc) have been assessed for the presence of clinical signs of vascular injury: Raynauds phenomenon, severity of capillary damage on capillaroscopy, presence or absence of finger‐tip ulcers or pitting scars, presence of telangiectasias and radiographic signs of finger‐tip osteolysis. Statistical significance of difference in clinical manifestations of peripheral vasculopathy in pts with lcSSc and dcSSc was assessed using the Mann-Whitney and X2 …‐test. Results: Duration of Raynauds phenomenon before manifestation of skin or internal organ damage, was significantly longer (z=−2.54, ...
Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs.[2][6][8] The disease can be either localized to the skin or involve other organs, as well.[2] Symptoms may include areas of thickened skin, stiffness, feeling tired, and poor blood flow to the fingers or toes with cold exposure.[1] One form of the condition, known as CREST syndrome, classically results in calcium deposits, Raynauds syndrome, esophageal problems, thickening of the skin of the fingers and toes, and areas of small, dilated blood vessels.[1] The cause is unknown, but it may be due to an abnormal immune response.[2] Risk factors include family history, certain genetic factors, and exposure to silica.[3][4][5] The underlying mechanism involves the abnormal growth of connective tissue, which is believed to be the result of the immune system attacking healthy tissues.[6] Diagnosis is based on symptoms, supported by a skin biopsy or blood tests.[6] While no ...
In 2002, a 10-week study published in the journal Vascular Medicine showed that the use of pharmaceutical grade gingko biloba reduced the number of painful ischemic attacks in 22 Raynauds sufferers by 57% compared to 27% in the placebo group. (Vasc Med. 2002;7(4):265-7. The use of Ginkgo biloba in Raynauds disease: a double-blind placebo-controlled trial. Muir AH1, Robb R, McLaren M, Daly F, Belch JJ.).. Gingko is believed to work as an anti-inflammatory agent reducing vascular breakdown and also by promoting vasodilation and thus opening up blood vessels in the hands and feet. Someone on medication should not take gingko biloba until a clinical nutritionist determines that negative gingko-drug interactions do not exist. He or she will also determine the proper dosage, which is based on body weight and metabolic rate. Physicians generally are not trained in the use of herbs and may not be familiar with studies that indicate gingko biloba has shown benefit to humans in a wide variety of ...