Rabbit recombinant monoclonal RAP1A + RAP1B antibody [EP879Y]. Validated in WB and tested in Mouse, Rat, Human. Cited in 2 publication(s). Independently reviewed in 3 review(s).

RAP1小鼠单克隆抗体[4c8/1](ab14404)可与人样本反应并经WB, IP, ELISA, IHC, Flow Cyt, ICC/IF实验严格验证并得到2个独立的用户反馈。所有产品均提供质保服务，中国75%以上现货。

You wish to get detailed details relating to the signs testing and treatments of IBS in men, you can get in touch with a health clinic or hospital that is closest to you and which provides these kinds of services. There are specialty nutrition clinics in the UK which assist to educate individuals about this particular syndrome. These centers not only help to inform individuals, they likewise assist to produce an awareness of this syndrome so that a growing number of people can be treated in time and without any more delay by which they may develop pains. This particular condition is one condition that impacts a great deal of individuals all around the world. Countless people all over the world go to see their medical professionals who identify them with this condition. Some clients might develop constipation together with this condition and this can result in the patient experiencing discomfort in the abdominal region ...

sir my father in law s suffering with brain disease which occured 10yrs back now he s not fine just behaiving like small child and mental but he recognise every one .Docters said that vn operation is done the chances are 50% .His behavior is horrible we cant tolerting he will beat to chidren nd wife..please give any suggetion…. ...

treatment for OCD. This type of therapy encourages patients to gradually encounter increasing doses of that which is contaminated, while resisting washing, checking, avoiding or conducting magical rituals. By staying with the anxiety, sufferers come to learn the truth of the matter-that nothing really happens when they face their fears, and that their efforts at taking precautions, therefore, serve no purpose. Gradually, patients learn to merge their clean and dirty worlds as they cease to protect themselves. They also concentrate on learning to accept that there will always be a certain amount of risk in life that can never be eliminated, and that life can still be enjoyed and lived freely in spite of this fact. By trying to eliminate risk, they come to see that, along with it, they will eliminate their ability to function. I like to tell my patients that When everything is contaminated, nothing is contaminated.. Therapeutic encounters are like small experiments to test patients theories ...

Social Networking is the grouping of individuals into specific groups, like small rural communities or a neighbourhood subdivision, if you will. Although

It is a type of allergy test. A drop of the suspected substance causing your reaction is placed on the skin.. In some instances the test is done using the juice from fresh fruit or using cooked food. This is called prick-to-prick testing. Your specialist will let you know if they need to do this test. They may ask you to bring the food to the clinic for the test. If more than one food is to be tested then you should bring the food in separate sealed containers like small Tupperware boxes or sandwich bags to keep the foods from touching each other and contaminating the test.. The skin is pricked with the solution with what looks like a mini plastic pencil. The skin is then wiped. It takes only 15 minutes to get the result.. ...

Hey, first post on this group. This may very well seem like small potatoes, but it is a constant, daily issue that I am striving to lay to rest. My DH (dear husband) snores sometimes, and its not the sleep apnea way (my dad has that and I remember that) it honestly sounds the way it does when you pretend to snore. He claims it is when he is falling asleep. Ive told him that snoring happens when you are actually asleep, no control over it. He says I only do it while I am falling asleep. I dont get it at all. I will ask him to stop, and he will, then he immediately does it again, and Ill ask again and he says I only did it once! I think, that means that then he isnt actually asleep! Anyway round and round we go. Its nuts. Does anyone have any insights, solutions or advice for this? I think its so fucking strange but we seem to be in stand off territory.

Social Networking is the grouping of individuals into specific groups, like small rural communities or a neighbourhood subdivision, if you will. Although

Frankford, NJ dentist and pediatrist specializing in dental implants, laser oral surgery, periodontics, Teeth-in-a-Day procedures, and family dentistry: David Goteiner, DDS FACD FICD, LLC

Please note: Your browser does not support the features used on Addgenes website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more ...

Background Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Description GDI2 Polyclonal Antibody, Biotin Conjugated....

Favorite styles: Abstract Hip-Hop, Alternative Rap, Beatboxing, British Rap, Comedy Rap, Crunk, Dirty Rap, Diss, East Coast Rap, Freestyle, G-Funk, Gangsta Rap, Glitch Hop, Hardcore rap, Horrorcore, Jazz-Rap, Live Looping, Old School Rap, Pop Rap, R&B, Southern Rap, Trap, Turntablism, West Coast Rap ...

In an influential essay with the title Do we need the concept of disease? the Swedish philosopher Germund Hesslow argues that the whole notion of disease is illusory and largely irrelevant to the practice of medicine.5 His case is based on the observation that what patients and doctors generally have to address is a wish to change or improve matters in one way or another, but this desire often maps poorly onto any idea of health or disease. He begins with a parable about a man who is upset because his car will not accelerate as fast as the same model owned by a friend, and who gets drawn into a fruitless argument with a mechanic who says he cannot find anything wrong with the engine. As Hesslow points out, what the customer is seeking is not a discussion about the meaning of words like faulty but a practical adjustment that will allow the car to do what he wants. Hesslow cites several states that are normally classified as diseases but not treated - like small birth marks or benign tumours - ...

We continue to work very hard in N2! We have improved as a whole in areas such as sitting at the table, putting our belongings in our cubbies independently, throwing out our trash after snack and walking quietly in the hallway. While this may seem like small potatoes...its quite a big deal around here! During our work time we have done both individual and small group lessons. Each week we will continue to learn a new lesson or two. Much of our focus has been on matching like objects (see donut game below), identifying colors and matching colors from our classroom environment. Again, you can reinforce this at home by playing games like I Spy or can you find me a ...

Looking at the new MacBook Air to replace my 12 Powerbook. I like small laptops. Its a flaw, I know.:D Regardless, this thread is not about which...

They look like small, translucent gems but these tiny gel slivers hold the world of a patients tumour in microcosm ready for trials of anti-cancer drugs to f

The new Apple iPad includes a better display, faster performance, better camera, and a snappy new operating system. Those may seem like small steps in the tablet space. But having used the new iPad for the past week now, I can tell you its a giant leap for connected mankind.

The latest Foxtel mag and a cattledog from Lakelands in the mail today. Lakelands is a very cool (and by cool I mean the kind of place that middle aged ladies in cardies who knit and make their own jam visit) homewares shop in the Lake District of the UK (hence the name). They sell all sorts of things you just cant walk into K Mart and get. Like small round plastic boxes that are just big enough to hold two biscuits, or one Lush shampoo soap. I ordered some of their wonderful lemon curd last time - the box was opened by Customs and a pamphlet placed inside informing me of all the things you cant bring into the country, such as fruit, eggs, sugar.... Hmmmm, all the things that lemon curd is made from, come to think of it. I think Customs let the curd through because its processed and none of the ingredients are raw. Its also incredibly wonderful. They also sell sticky gloves - theyre square and very sticky on one side and you put your hand in and they pick up fluff and cat hair from all ...

Effective dog training does not require many items, but there are a few basic supplies that will help make the process more convenient and effective. Choose a dog collar or harness that is suitable and comfortable for your dog. Then decide which dog leash is best for training. A retractable leash is not appropriate for dog training. You will also need dog training treats that your dog enjoys and are easy to eat quickly so the reward is more immediate. There are plenty of great treats available at pet stores or you can also use something you make at home, like small pieces of plain cooked chicken or turkey. ...

my back was itchy one day and i thought nothing of it. but later that same day my chest got really itchy and i noticed that i had a rash. it kinda looked like small little pimples, only it was very itc...

Covid-19 has caused many issues not just in the UK but globally, shutting down things like small businesses all the way up to countries to try to prevent the spread of the virus. With everything shutting down many other effects have come into play for people, less access to support networks, less time with friends, …. ...

I love these milestones, that may seem like small things to the parent of the neuro-typical child. Just one more step on the journey to making herself heard and understood. I am convinced that if we can get a greater level of communication going between Anneliese and ourselves as parents, her tantrums and meltdowns will be cut by half ...

Corporate finance theories suggest that problems of asymmetric information and moral hazard in credit markets can be addressed by choosing short-term maturities. Theories of debt renegotiation suggest that the credibility of the implicit commitment to not make concessions to insolvent borrowers, which would undermine the effectiveness of short-term maturities, is related to the characteristics of the lender and in particular to its size. the joint implication of these theories is that, for given borrowers characteristics, small banks should be less willing to issue long term, loans. Using information on Italian banks, this study presents a cross-sectional analysis of the maturity of loans to firms and shows a first evidence consistent with this prediction. With more opaque borrowers, like small and innovative firms, other supply-side features (special regulatory regimes favouring lending relationships and economies of scale in the screening technology) are also shown to be relevant in the ...

How to Survive a Freestyle Rap Battle. Rap battles can be a great opportunity for a rapper to showcase their talents. In a rap battle, the rapper with the best delivery, lyrics, and crowd response usually wins. By writing your own rap...

We are developing our application in RCP and then migrate it to RAP and to have less compatible issue between RCP & RAP, we have chosen Eclipse Juno (latest version) for the development. Is there any other feature which works in RCP and not compatible with RAP ...

Rap2B is a 21 kDa small GTP-binding protein that that exhibits 46% identity with Ras proteins and is similarly post-translationally modified by…

View mouse Rap1gap2 Chr11:74383356-74610915 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression

365 CashHounds was a rap group created by Yo Mans TAY and his cousin Donni Luchi back around 2009. Through the years the rap group has gro ...

NCB-0846 Featured NCB-0846 is a novel,first-in-class,orally TNIK inhibitor with an IC50 value of 21 nM,that have shown strong anti-tumor efficacy against several cancer models.. ...

View mouse Rap1b Chr10:117814597-117845974 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression

DeStorm - 2013 Rap Up. It doesnt matter where we go (Dont matter). As long as were going harder (As long as we go harder). We going harder (Yeah). We going harder (We going harder). Complete Full Song Lyrics.

Lizzo thinks rap made her a better singer. The Juice hitmaker spent years honing her craft and thinks that has helped her with her career now because

Vaasankadun myymälä on suljettu ja se muuttaa Hakaniemen Äxän yläkerran tiloihin perjantaina 30.6. Jos sinulla on noutamattomia varauksia niin ne löytyypi nyt Hakaniemen myymälästä.. ...

Aubé C. (rap.), Beuf O. (dir.), Cozar O., Lartizien C. (co-dir.), Pilleul F., Saint-Jalmes H. (rap.), Scoazec J.Y. (prés.), Volk A ...

Methinks she hasnt a clue. I see nothing particularly Jungian about the way her character works. But then again, I doubt that anyone could clearly identify me as Jungian by observing me either. ...

Pittsburghs Boaz is making a lot of progress towards establishing himself as one of the citys finest rap talents. His brand of street rap straight from

somtimes it just doesnt seem worth it. Ive been in this cycle of feeling depressed and worrying non stop about everything. Its like my brain is on a speed rap and....

As a debut, Earl Sweatshirts Doris accomplishes two things: It inaugurates him into a new class of rap stardom. And confirms that everything he does - both as

Experiences enrich the brain. Possessions fracture its energy, focus and attention. When outer world objects such as people, problems, social media, etc. take so much of your attention and energy, there is little left for you to put on your inner world of thoughts and feelings. What you own eventually comes to own you - becoming a victim of your life rather than the creator of your life. Too many outside distractions gets your brain to fire out of order and to work inefficiently and out of sync. When your brain is incoherent, you get incoherent. How much of your energy is taken up by possessions, fear, greed, envy, etc. that could otherwise be put to creating a new destiny? This is a shift from somebody to no body, from something to no thing, from being somewhere to being no where, from being in linear time to being in no time. The different compartments that were once subdivided now start to unify and move toward a coherent, whole-brain state - where your brain can synchronize, organize and ...

RGL3 (ral guanine nucleotide dissociation stimulator like 3), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.

The reliable prediction of the precise three-dimensional structure of proteins from their amino acid sequence is a major, still unresolved problem in biochemistry. Pressure is a parameter that controls folding/unfolding transitions of proteins through the volume change DeltaV of the protein-solvent system. By varying the pressure from 30 to 2,000 bar we detected using 15N/ 1H 2D NMR spectroscopy a unique equilibrium unfolding intermediate I in the Ras binding domain of the Ral guanine nucleotide dissociation stimulator (Ral GDS). It is characterized by a local melting of specific structural elements near hydrophobic cavities while the overall folded structure is maintained. ...

The angiotensin II type 1 receptor (AT1R) plays an important role in cardiovascular function and as such represents a primary target for therapeutic intervention. The AT1R has traditionally been considered to be coupled to the activation of phospholipase C (PLC) β via its association with Gαq/11, leading to increases in intracellular inositol phosphate (IP) and release of calcium from intracellular stores. In the present study, we investigated whether the small GTPase RalA contributed to the regulation of AT1R endocytosis and signaling. We find that neither RalA nor RalB is required for the endocytosis of the AT1R, but that RalA expression is required for AT1R-stimulated IP formation but not 5-HT2A receptor-mediated IP formation. AT1R-activated IP formation is lost in the absence of Ral guanine nucleotide dissociation stimulator (RalGDS), and requires the β-arrestin-dependent plasma membrane translocation of RalGDS. Gαq/11 small interfering RNA (siRNA) treatment also significantly attenuates ...

Question - Bump on penis, feels like small ball under skin. What is this bump?. Ask a Doctor about diagnosis, treatment and medication for Acne vulgaris, Ask a Urologist

Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the RAP1B gene. GRCh38: Ensembl release 89: ENSG00000127314 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000052681 - Ensembl, May 2017 Human PubMed Reference:. Mouse PubMed Reference:. Entrez Gene: RAP1B. Pizon V, Lerosey I, Chardin P, Tavitian A (August 1988). Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B). Nucleic Acids Res. 16 (15): 7719. doi:10.1093/nar/16.15.7719. PMC 338441 . PMID 3137530. Matsui Y, Kikuchi A, Kawata M, Kondo J, Teranishi Y, Takai Y (January 1990). Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B. Biochem. Biophys. Res. Commun. 166 (2): 1010-6. doi:10.1016/0006-291X(90)90911-6. PMID 2105724. Rousseau-Merck MF, Pizon V, Tavitian A, Berger R (1990). Chromosome mapping of the human RAS-related RAP1A, RAP1B, and RAP2 genes to chromosomes ...

Given its effects on cell spreading and motility, Rap1 was postulated some time ago to be involved in integrin function; however, confirmation of this required alternative cellular models. Leukocytes represented such a model, since the positive effect of GTP-bound Rap1 on integrin-mediated adhesion is easier to see: in blood cells, in contrast to the more traditional, fibroblast and epithelial, adherent cell systems, integrins are normally kept inactive. Upon inside-out signalling elicited by various agonists, leukocyte integrins can rapidly and transiently be converted to a functionally active, ligand-binding state able to trigger the classic outside-in signalling to Rho-like GTPases (Harris et al., 2000; Schoenwaelder and Burridge, 1999).. Rap1 regulates functional activation of several integrin heterodimers:α 4β1 (VLA-4), α5β1 (VLA-5), αLβ2 (LFA-1, CD11a/CD18), αMβ2 (CR3, CD11b/CD18) and αIIbβ3 (Reedquist et al., 2000; Caron et al., 2000; Katagiri et al., 2000; Arai et al., 2001; ...

begingroup$ Interesting question! @Chris has a good point. I think the relevant factor is how often a long-lived stem cell (or similar) would divide in these two tissues. Is prostate less proliferative than small intestine in this regard? Also, some cell types maintain a more differentiated state while proliferating (hepatocytes in regenerating liver, for example) and this could be a factor I think. Just some suggestions. $\endgroup$ - Roland Oct 21 16 at 8:59 ...

Rap1 family GTPase consists of Rap1a and Rap1b isoforms. The Rap1 subgroup is part of the Rap subfamily of the Ras family. It can be further divided into the Rap1a and Rap1b isoforms. In humans, Rap1a and Rap1b share 95% sequence homology, but are products of two different genes located on chromosomes 1 and 12, respectively. Rap1a is sometimes called smg p21 or Krev1 in the older literature. Rap1 proteins are believed to perform different cellular functions, depending on the isoform, its subcellular localization, and the effector proteins it binds. For example, in rat salivary gland, neutrophils, and platelets, Rap1 localizes to secretory granules and is believed to regulate exocytosis or the formation of secretory granules. Rap1 has also been shown to localize in the Golgi of rat fibroblasts, zymogen granules, plasma membrane, and the microsomal membrane of pancreatic acini, as well as in the endocytic compartment of skeletal muscle cells and fibroblasts. High expression of Rap1 has been ...

Nagata K et al. (1989) Purification, identification, and characterization of two GTP-binding proteins with molecular weights of 25,000 and 21,000 in human platelet cytosol. One is the rap1/smg21/Krev-1 protein and the other is a novel GTP-binding protein.. ...

Rabbit monoclonal antibody raised against a human RAP1GDS1 peptide using ARM Technology. A synthetic peptide of human RAP1GDS1 is used for rabbit immunization.Customer or Abnova will decide on the preferred peptide sequence. (H00005910-K) - Products - Abnova

Mouse anti Human RAP1A/B antibody recognizes the Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, Ras family small

Fig. 1. Effect on cell growth of deletions within theRAP1 gene. (A) Plate assays showing the growth of yeast strains expressing deletion derivatives of Rap1p. In each case, transformed colonies selected on gal plates were diluted and single spots containing 104, 103, 102, and 10 cells were plated onto gal and glu plates. The plates were incubated for 4 days at 30°C and photographed. The diagrams on the right show the Rap1p derivatives expressed in each strain. The numbers indicate which amino acids from the Rap1p primary sequence were present. The large shaded area in the middle of each sequence indicates the DNA binding domain, and the smaller shaded area indicates the C-terminal activation domain. (B) Growth curves of Rap1p deletion strains in glu medium. Each strain was inoculated at a cell density of 104cells/ml. The cultures were incubated with shaking at 30°C, and aliquots taken at intervals for optical density at 600 nm (OD600) readings. (C) Western blot showing the expression of Rap1p ...

The self-proclaimed OG Khaligraph Jones has once again left his fans in complete awe with another dope freestyle session.. When he is not dropping new music, the Micasa Sucasa rapper keeps his over 150,000 followers on Instagram entertained with weekly freestyle sessions.. Usually shot inside his ride, the sessions have become a big hit as the rapper shows his versatility with amazing rap flows.. In his previous sesh, Khaligraph took up his rap alter-ego Kasee and impressively showed off his Kamba rap flow.. Now, the talented rapper can apparently rap in Jamaican. In his latest sesh, he effortlessly switches from a Dancehall flow to a rap flow and it is thoroughly entertaining and impressive.. Check it out:. ...

These Dog Alliteration poems are examples of Alliteration poems about Dog. Alliteration is focused on the sound of a word. Indeed, gangsta raps in-your-face style may do more to force America to. Hi my name is sahil and im gonna tell you. These word represent an alliteration because, the g is repeating in the first letter of going, good, going, and great. Poème de Paul Valéry. Alex asked in Entertainment & Music Music Rap and Hip-Hop · 1 decade ago Whats a good Rap song with alliteration? No underground rappers please,I need rappers like lil wayne eminiem drake birdman and people like that. To write a rap verse, start by writing lines about your topic and trying to rhyme the last words in each line. Anaphora is a literary and rhetorical device in which a word or group of words is repeated at the beginning of two or more successive clauses or sentences. In this original song, I rap about alliteration, while using alliteration. Alliteration is a special case of consonance where the repeated ...

Peptides that act like small molecules are highly desirable as drug candidates for targeting larger proteins and peptide specific binding sites. Hybridtides are

ANSWER: Scabies often looks like small red pimple-like bumps on the skin. The bumps may be crusty. They may also be accompanied by burrows, or thin gray, brown, or red lines that radiate from the bumps. They may be hard to see, and can look like scratch marks.

Weve managed to create a very complex network in a very small area, says Dan Nicolau, Sr. with a laugh. He began working on the idea with his son, Dan Jr., more than a decade ago and was then joined by colleagues from Germany, Sweden and The Netherlands, some 7 years ago. This started as a back of an envelope idea, after too much rum I think, with drawings of what looked like small worms exploring mazes.. The model bio-supercomputer that the Nicolaus (father and son) and their colleagues have created came about thanks to a combination of geometrical modelling and engineering knowhow (on the nano scale). It is a first step, in showing that this kind of biological supercomputer can actually work. The circuit the researchers have created looks a bit like a road map of a busy and very organized city as seen from a plane. Just as in a city, cars and trucks of different sizes, powered by motors of different kinds, navigate through channels that have been created for them, consuming the fuel they ...

Small talk is one of my least favorite things ever. Most introverts like myself say they dont like small talk because it forces them to step out of their

Instinctively, the young puppy will, like small children, put anything in their mouth as a way of investigating the world. The investigation involves testing out how hard the object is, but it is also training for the future, where the mother, in the wild, brings home larger pray as food for the litter.. The puppy has to learn how to tear the meat off the bone and how to chew up even the toughest sinews in a carcass.. Our domesticated pups, brought home at eight weeks old, will be fed a mere shadow of that natural food and most new puppy owners help the puppy to satisfy its need for chewing by giving it various chew-toys.. As the puppy starts to lose the puppy teeth, the gums get itchy and chewing really takes hold then. This is the point where you as an owner can satisfy the puppys needs, but at the same time try to manage the chewing, so that it does not become a lifelong habit.. Lets firstly be clear: some dogs grow up to become chewers no matter what you do, so it is not always your ...

In the distance, it looks like small white flowers growing on the dry branches. But, if you look closely, youll notice that there are small shells, its the Mediterranean snail.I saw thousands of them! I just dont understand why they are attracted to the dry plants. I read its a well-known agricultural pest in many…

I have had none-pain swelling in right sided occipital lymph node and stationary swelling like small olives in other lymph nodes in right side of neck...no pain.... Two days ago the swelling increased...

Expression of RAP1GAP (KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII) in heart muscle tissue. Antibody staining with HPA001922 in immunohistochemistry.

Expression of RAP1GAP (KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII) in lung tissue. Antibody staining with HPA001922 in immunohistochemistry.

CDK5RAP1 antibody (CDK5 regulatory subunit associated protein 1) for ICC/IF, IHC-P, WB. Anti-CDK5RAP1 pAb (GTX111910) is tested in Human, Rat samples. 100% Ab-Assurance.

I was curious what you guys think about . Rapala jigging rap vis hyper glide, or any other jigging style. any thought with one is better. I only been using the jigging rap for a couple years. I really hate loosing these. $$$

Photo credit: Science With Tom. Plasmid Rap is a great rap that teaches students what a plasmid is and the applications that are used in biotechnology. The music is inspired by the song Beware by Big Sean.. ...

SLAT promotes T cell activation and differentiation by regulating NFAT-Ca(2+) signaling. However, its role in TCR-mediated inside-out signaling

Lyrics to I Run Rap by Dr. Dooom: [dr. Dooom] / Yeah / Number one mc in the world, A. K. A. Dr. Dooom / Straight out of solitary / I got

WARNING: PLEASE NOTE THAT GOOGLE ADS ARE KEYWORD DRIVEN, SO WE DO NOT CONTROL THE ADS AND WE DO NOT VOUCH FOR ANY ADVERTISED PRODUCTS OR SERVICE (in fact, BUYER BEWARE ...

Pr. Y. Meyer (rap.), Pr. M. Deville (rap.), Pr. D. Jeulin (rap.), Pr. B. Torrésani, Pr. P. Bourgin, Pr. G. Flouzat, Pr. J.L. Lacoume, Pr. M. Jourlin (dir ...

No matter who we are, no matter where we live, were all bound by borders. Many of us are content to live within these borders--others are simply forced to exist within them. But some of us need to break out, burst through, even if what is on the oth

Simply put, this track is mind blowing. If you have yet to hear it, please take a listen below. We get the feeling that Em was using this track to flex his muscles, and reach out to all of those who may have said he has fallen off. The song starts with a quick blurb... look... I was going to go easy on you not to hurt

Specializing in drafts with top players on the NBA horizon, player profiles, scouting reports, rankings and prospective international recruits.

Saw this while watching the boob tube yesterday. For 7 Ups latest ad campaign, the soft drinker commissions Cee-Lo Green and his 2002 hit Closet Freak.

Listening to the greats such as KRS-One lay out the birth of hip-hop as they both watched and helped it grow there is one thing that becomes exceedingly

Far far away, behind the word mountains, far from the countries Vokalia and Consonantia, there live the blind texts. Separated they live in Bookmarksgrove right ...

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