Contents: The Fundamentals.- The History of Stereotactic Radiosurgery.- Neuroimaging in Radiosurgery Treatment Planning and Follow-up Evaluation.- Techniques of Stereotactic Radiosurgery.- Radiation Biology and Physics.- The Physics of Stereotactic Radiosurgery.- Radiobiological Principles Underlying Stereotactic Radiation Therapy.- Experimental Radiosurgery Models.- Treatment Planning for Stereotactic Radiosurgery.- Designing, Building and Installing a Stereotactic Radiosurgery Unit.- Stereotactic Radiosurgery Techniques.- Gamma Knife Radiosurgery.- Linear Accelerator Radiosurgery.- Proton Beam Radiosurgery: Physical Bases and Clinical Experience.- Robotics and Radiosurgery.- CyberKnife Radiosurgery.- Treatment of Disease Types.- Brain Metastases.- Metastatic Brain Tumors: Surgery Perspective.- Brain Metastases: Whole-Brain Radiation Therapy Perspective.- High-Grade Gliomas.- Malignant Glioma: Chemotherapy Perspective.- Meningioma.- Meningioma: Surgery Perspective.- Intracranial Meningioma: ...

This study compares administration schedules of experimental MPDL3280A (antibody- a protein produced by the bodys immune system) and stereotactic ablative radiotherapy in treating patients with lung cancer. MPDL3280A, may block tumor growth in different ways by targeting certain cells. Stereotactic ablative radiotherapy, is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may kill more tumor cells and cause less damage to normal tissue. Giving MPDL3280A with stereotactic ablative radiotherapy may be a better treatment for lung cancer. However, it is not yet known what the best administration schedule is for these treatments. ...

TY - JOUR. T1 - CyberKnife radiosurgery in four cases of choroidal malignant melanoma. AU - Tabira, Emi. AU - Yoshikawa, Hiroshi. AU - Kawano, Yoh Ichi. AU - Ueno, Ichiro. AU - Kohno, Ri Ichiro. AU - Hasegawa, Yuhei. AU - Ishibashi, Tatsuro. PY - 2010/11/15. Y1 - 2010/11/15. N2 - Purpose : To report four cases who received CyberKnife radiosurgery for choroidal malignant melanoma. Cases : CyberKnife radiosurgery was performed on 4 cases of choroidal malignant melanoma. The series comprised 3 males and one female. The age ranged from 57 to 82 years. The height of the tumor ranged from 2.8 to 6.7 mm, average 5.3 mm. Each eye received a case 10 Gy of radiation per session totaling 50 Gy after 5 sessions. The tumor showed a decrease in size. The height ranged 0.2 to 5.2 mm, average 3.9 mm after 6 to 36 months of treatment. One eye developed vitreous hemorrhage. Otherwise, there was no local recurrence or rubeotic glaucoma. Conclufion : CyberKnife radiosurgery was effective in four cases of choroidal ...

TY - JOUR. T1 - Imaging characteristics of local recurrences after stereotactic body radiation therapy for stage I non-small cell lung cancer. T2 - Evaluation of mass-like fibrosis. AU - Hayashi, Shinya. AU - Tanaka, Hidekazu. AU - Hoshi, Hiroaki. PY - 2015/3/1. Y1 - 2015/3/1. N2 - Background: This study aimed to evaluate stereotactic body radiation therapy (SBRT) in patients with stage I non-small cell lung cancer (NSCLC) in terms of radiation-induced changes and computed tomography (CT) features of local recurrence by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET). Methods: From January 2006 to December 2012, 81 patients with NSCLC received SBRT. Follow-up consisted of non-contrast enhanced CT scans performed before and every four months after SBRT. In addition, 18F-FDG-PET/CT was conducted before SBRT for each patient, and one year later for each case suspected of recurrence. The CT findings were classified into two categories: mass-like fibrosis and others. The mass-like ...

The researchers found that there was less cognitive deterioration at 3 months after stereotactic radiosurgery alone (40/63 patients, 64%) than when combined with whole brain radiotherapy (44/48 patients, 92%). Quality of life was higher at three months with stereotactic radiosurgery alone, including overall quality of life. There was no significant difference in functional independence at three months between the treatment groups. Median overall survival was 10.4 months for stereotactic radiosurgery alone and 7.4 months for stereotactic radiosurgery plus whole brain radiotherapy. For long-term survivors, the incidence of cognitive deterioration was less after stereotactic radiosurgery alone at three months and at 12 months.. In the absence of a difference in overall survival, these findings suggest that for patients with one to three brain metastases amenable to radiosurgery, stereotactic radiosurgery alone may be a preferred strategy, the authors write.. The debate between whole brain ...

Research by Beaumont Health System radiation oncologists and neurosurgeons found that symptoms of trigeminal neuralgia, or TN, a nerve disorder causing severe facial pain, were reduced in those treated with Gamma Knife stereotactic radiosurgery. The results were published recently in the journal Clinical Neurology and Neurosurgery.

Looking for Gamma Knife Surgery? Find out information about Gamma Knife Surgery. branch of medicine medicine, the science and art of treating and preventing disease. History of Medicine Ancient Times Prehistoric skulls found in Europe... Explanation of Gamma Knife Surgery

Effect of Ape1/Ref-1 on injury caused by stereotactic ablative radiotherapy in the treatment of early stage non-small cell lung cancer, Lei Han, Renzhi Yu, Xin Ni, Zenglei Zhang

Objective: To explore the effect of Ape1/Ref-1 on injury caused by stereotactic ablative radiotherapy in the treatment of early stage non-small cell l..

Nieder, Carsten; Andratschke, Nicolaus H; Guckenberger, Matthias (2015). A pooled analysis of stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small cell lung cancer: is failure to recruit patients into randomized trials also an answer to the research question? Annals of Translational Medicine, 3(11):148-151. ...

Brain metastases from systemic cancer remains a significant source of morbidity and mortality. The clinical results of gamma knife radiosurgery for brain metastases are analyzed to identify treatment parameters and ascertain effectiveness correlated with local tumor control. Between May 1990 and August 1993, 103 patients with brain metastases were treated with gamma knife radiosurgery. Forty four patients had single metastasis. But the rest of the patients had multiple brain metastases: two lesions in 22 patients, three lesions in 13 patients, and more than four lesions in 24 patients. They were expected to survive more than three months and their Karnofsky performance scores were 70% or more. Fifty nine patients underwent radiosurgery only. Seventeen patients had received adjuvant whole brain radiotherapy(WBRT) with radiosurgery. Among 27 patients who underwent tumor resection and radiosurgery, 10 patients had received combined WBRT also. Despite of 91.6% of local tumor control, overall median ...

The purpose of this study was to compare patterns of failure between lobar resection (lobectomy or pneumonectomy) and stereotactic body radiation therapy (SBRT) for patients with clinical stage I non-small-cell lung cancer (NSCLC). From January

Find the best gamma knife radiosurgery doctors in Gurgaon. Get guidance from medical experts to select gamma knife radiosurgery specialist in Gurgaon from trusted hospitals - credihealth.com

Find the best gamma knife radiosurgery doctors in Navi Mumbai. Get guidance from medical experts to select gamma knife radiosurgery specialist in Navi Mumbai from trusted hospitals - credihealth.com

TY - JOUR. T1 - Stereotactic body radiation therapy of liver tumors. T2 - post-treatment appearances and evaluation of treatment response: a pictorial review. AU - Haddad, Mustafa M.. AU - Merrell, Kenneth W.. AU - Hallemeier, Christopher. AU - Johnson, Geoffrey B. AU - Mounajjed, Taofic. AU - Olivier, Kenneth R.. AU - Fidler, Jeff L.. AU - Venkatesh, Sudhakar K. PY - 2016/5/11. Y1 - 2016/5/11. N2 - Stereotactic body radiation therapy (SBRT) is a noninvasive treatment technique for selected patients with primary liver tumors and liver-confined oligometastatic disease. Recently, SBRT has emerged as an alternative treatment option in non-surgical candidates and in whom percutaneous treatment methods are not possible or contraindicated. The experience with SBRT continues to grow. There are currently no imaging guidelines for assessment of tumor response and follow-up schedule following SBRT. SBRT produces characteristic radiation-induced changes in the treated tumor and surrounding liver ...

TY - JOUR. T1 - Electromagnetic navigational bronchoscopy-guided fiducial markers for lung stereotactic body radiation therapy. T2 - Analysis of safety, feasibility, and interfraction stability. AU - Nabavizadeh, Nima. AU - Zhang, Junan. AU - Elliott, David A.. AU - Tanyi, James A.. AU - Thomas, Charles R.. AU - Fuss, Martin. AU - Deffebach, Mark. PY - 2014/4. Y1 - 2014/4. N2 - Background: Embolization coils as fiducial markers for pulmonary stereotactic body radiation therapy (SBRT) are perceived to be the optimal marker type, given their ability to conform and anchor within the small airways. The aim of our study was to assess retention, placement, migration, feasibility, and safety of electromagnetic navigational bronchoscopy (ENB)-guided embolization coil markers throughout courses of SBRT. Methods: Thirty-one patients with 34 nodules underwent ENB-guided fiducial placement of several 4mm fibered platinum embolization coils before SBRT. Patient and nodule positioning was confirmed with daily ...

TY - JOUR. T1 - Feasibility of non-coplanar tomotherapy for lung cancer stereotactic body radiation therapy. AU - Yang, Wensha. AU - Jones, Ryan. AU - Lu, Weiguo. AU - Geesey, Constance. AU - Benedict, Stanley H. AU - Read, Paul. AU - Larner, James. AU - Sheng, Ke. PY - 2011/8. Y1 - 2011/8. N2 - To quantify the dosimetric gains from non-coplanar helical tomotherapy (HT) arcs for stereotactic body radiation therapy (SBRT) of lung cancer, we created oblique helical arcs by rotating patients CT images. Ten, 20 and 30 degrees of yaws were introduced in the treatment planning for a patient with a hypothetical lung tumor at the upper, middle and lower portion of the right lung, and the upper and middle left lung. The planning target volume (PTV) was 43 cm 3. 60 Gy was prescribed to the PTV. Dose to organs at risk (OARs), which included the lungs, heart, spinal cord and chest wall, was optimized using a 2.5 cm jaw, 0.287 pitch and modulation factor of 2.5. Composite plans were generated by dose ...

Stereotactic ablative radiotherapy (SABR) shows a remarkable local control of non-small cell lung cancer (NSCLC) metastases, partially as a result of host immune status. However, the predictors of immune cells for tumor response after SABR are unknown. To that effect, we investigated the ability of pre-SABR immune cells in peripheral blood to predict early tumor response to SABR in patients with lung metastases from NSCLC. This study included 70 patients with lung metastases from NSCLC who were undergoing SABR. We evaluated the early tumor response 1 month and 6 months after SABR in these patients following RECIST 1.1 guidelines. Pre-SABR peripheral CD8+ T cell count, CD8+CD28+ T-cell count, CD8+CD28− T-cell count, CD4+ T-cell count, and Treg-cell count were measured using flow cytometry. Increased CD8+CD28+ T-cell counts (14.43 ± 0.65 vs. 10.21 ± 0.66; P = 0.001) and CD4/Treg ratio (16.96 ± 1.76 vs. 11.91 ± 0.74; P = 0.011) were noted in 1-month responsive patients, compared with non-responsive

This study aimed to evaluate the effect of stereotactic ablative radiotherapy (SABR) after incomplete transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) patients. The study enrolled 178 HCC patients initially treated with TACE between 2006 and 2011. Patients were included if they had Barcelona Clinic Liver Cancer stage 0 or A, ≤3 nodules with a total sum of longest diameter ≤10 cm, Child-Turcotte-Pugh score of ≤7, no major vessel invasion, and no extra-hepatic metastases. Twenty-four patients achieved a complete response to TACE (group 1). Among those with incomplete response, 47 patients received other curative treatments (group 2), 37 received SABR (group 3), and 70 received non-curative treatments (group 4). The 2-year overall survival (OS) rates for groups 1, 2, 3, and 4 were 88 %, 81 %, 73 %, and 54 %, respectively. The corresponding 5-year OS rates were 50 %, 58 %, 53 %, and 28 %, respectively. Patients treated with SABR after incomplete TACE had similar

TY - JOUR. T1 - Stereotactic radiosurgery of residual or recurrent craniopharyngioma. T2 - New treatment concept using leksell gamma knife model C with automatic positioning system. AU - Yomo, Shoji. AU - Hayashi, Motohiro. AU - Chernov, Mikhail. AU - Tamura, Noriko. AU - Izawa, Masahiro. AU - Okada, Yoshikazu. AU - Hori, Tomokatsu. AU - Iseki, Hiroshi. PY - 2009/11/1. Y1 - 2009/11/1. N2 - Background/Aims: The present study analyzed the initial experience with the application of the original concept of robotic microradiosurgery using Leksell Gamma Knife Model C with automatic positioning system for management of craniopharyngiomas. Methods: Eighteen patients with residual or recurrent craniopharyngiomas underwent radiosurgery with the use of multiple isocenters, mainly of smaller size, which were positioned compactly within the border of the lesion with resultant improved dose homogeneity, increased average dose within the target, and sharp dose fall outside the treated volume. Treatment ...

The Japanese Ministry of Health, Labor and Welfare (MHLW) gave the latest CyberKnife Radiosurgery the Shonin approval. The CyberKnife G4 Robotic Radiosurgery Systems from Accuray Inc., will be available in Japan to treat tumors non-invasively anywhere in the body, including head and neck. This regulatory approval dramatically expanded the types of Japanese patients that could be treated with radiosurgery to include those with cancers of the spine, lung, liver, pancreas and prostate.. The CyberKnife G4 System addresses the unique challenges of random and excessive target motion by using intelligent and adaptive image guidance, which minimizes dose to surrounding healthy tissue and critical structures, ultimately minimizing treatment complications and side effects.. The CyberKnife G4 System will provide Japanese patients with some of the latest advances in CyberKnife technology including: Motion management technology to correct for tumor motion including the Xsight Lung Tracking System, which ...

TY - JOUR. T1 - Gamma knife radiosurgery for large volume brain tumors. T2 - An analysis of acute and chronic toxicity. AU - Linzer, D.. AU - Ling, S. M.. AU - Villalobos, H.. AU - Raub, W.. AU - Wu, X.. AU - Ting, J.. AU - Berti, A.. AU - Landy, H.. AU - Markoe, A. M.. PY - 1998/11/2. Y1 - 1998/11/2. N2 - Gamma Knife radiosurgery is often used to treat intracranial tumors ,4 cm (approximately 13.5 cm3) in mean diameter. Larger lesions are rarely treated because of the expectation that increasing target volume will increase toxicity. We retrospectively analyzed 35 patients with primary or metastatic brain tumors of more than 13.5 cm3 treated with the Gamma Knife. Only 3 (8.5%) patients developed acute clinical toxicity. Nine (25%) patients developed post-Gamma Knife radionecrosis based on imaging studies, with only 3 of these patients (9% of the study population) having clinical progression of symptoms. Necrosis was not found to be related to prescribed dose, treatment volume or number of ...

SAN FRANCISCO, Oct. 15 /PRNewswire/ -- Elekta will showcase updates to its Leksell GammaPlan® 10.0* treatment planning software for Leksell Gamma Knife® and the Extend™ program for Leksell Gamma Knife® Perfexion™ at the 2010 Congress of Neurological Surgeons [1] (CNS) Annual Meeting, October 16-21 at the Moscone Convention Center in San Francisco. The Extend program [2] dramatically broadens the types of cases for which clinicians can use Perfexion.. On the show floor, Elekta booth #109 will feature hands-on demonstrations of Extend, which combines patient-friendly head immobilization technology and stereotactic localization methods to permit hypofractionated Gamma Knife treatments [3] for larger tumors or lesions close to critical structures located in the brain, skull base and other head and neck regions.. Updates to GammaPlan 10.0 [4] include the two optional add-ons Inverse Planning and Convolution. Inverse Planning provides a fast, easy solution for Gamma Knife surgery planning, ...

Elekta delivers Leksell Gamma Knife® to HM Queen Sophia Hospital in Stockholm. The Sophiahemmet Private Hospital in Stockholm announced yesterday that it will install Sweden's second Leksell Gamma Knife® unit in a newly formed Leksell Gamma Knife® Center at Sophiahemmet. The Leksell Gamma Knife® unit to Sophiahemmet was included in the orders during the second quarter valued at in total SEK 155 M announced by Elekta on 13 November 2001.. For further information please click here to read the press release from Sophiahemmet 20 November 2001.. Elekta is a world-leading supplier of advanced and innovative radiation oncology and neurosurgery solutions and services for precise treatment of cancer and brain disorders. Elekta's solutions are clinically effective and cost efficient and gentle to the patient. ...

TY - JOUR. T1 - Stereotactic body radiation therapy. T2 - Rationale, techniques, applications, and optimization. AU - Song, Danny Y.. AU - Kavanagh, Brian D.. AU - Benedict, Stanley H. AU - Schefter, Tracey. PY - 2004/10. Y1 - 2004/10. N2 - Stereotatic body radiation therapy (SBRT) is a rapidly evolving cancer treatment method in which concepts and techniques previously developed for brain tumor radiosurgery are adapted to eradicate tumors elsewhere in the body. The spatial accuracy, conformality, and steep radiation dose gradients of radiosurgery, which have been critical to its success in the treatment of intracranial tumors, are applied in SBRT to treat a variety of extracranial tumors. Early results demonstrate excellent response rates and low toxicity with a variety of hypofractionated dose regimens and localization/immobilization techniques. This article provides an overview of the rationale and results of SBRT for specific indications, descriptions of some methods of treatment delivery, ...

The Jewish Hospital - Mercy Health offers minimally-invasive brain surgery through state-of-the-art, pinpoint-accurate radiosurgery. The Jewish Hospital features Leksell Gamma Knife® Perfexion™, an advanced radiosurgical device that uses radiation to perform precision brain surgery with no incisions. This technology is the first of its kind in Greater Cincinnati. The Jewish Hospital is one of approximately 250 hospitals worldwide to offer this life-extending treatment.. The Gamma Knife® treats brain tumors and neurological conditions without the normal risks associated with surgery and a long hospital stay. Gamma Knife® radiosurgery uses 192 beams of radiation to precisely target tumors deep within the brain without incisions. Most patients are able to go home the same day. More than 30 years of clinical studies documented in more than 2,500 published medical papers demonstrate the effectiveness of Gamma Knife® radiosurgery.. With the Gamma Knife® Perfexion™, The Jewish Hospitals ...

Doctors give unbiased, trusted information on the use of Gamma Knife Surgery for Meningioma: Dr. Bonuel on radiation necrosis after gamma knife surgery for meningioma: Stereotactic surgery is usually a minimally invasive procedure using x-ray and computers to locate a spot or lesion to perform a needle biopsy through a very small incision. Gamma knife is a non-invasive procedure to deliver very carefully a high dose of radiation therapy with specialized equipment to treat a lesion or tumor with no incision.

TY - JOUR. T1 - Tumor control probability modeling for stereotactic body radiation therapy of early-stage lung cancer using multiple bio-physical models. AU - Liu, Feng. AU - Tai, An. AU - Lee, Percy. AU - Biswas, Tithi. AU - Ding, George X.. AU - El Naqa, Isaam. AU - Grimm, Jimm. AU - Jackson, Andrew. AU - Kong, Feng Ming. AU - LaCouture, Tamara. AU - Loo, Billy. AU - Miften, Moyed. AU - Solberg, Timothy. AU - Li, X. Allen. N1 - Publisher Copyright: © 2016 Elsevier Ireland Ltd. PY - 2017/2/1. Y1 - 2017/2/1. N2 - This work is to analyze pooled clinical data using different radiobiological models and to understand the relationship between biologically effective dose (BED) and tumor control probability (TCP) for stereotactic body radiotherapy (SBRT) of early-stage non-small cell lung cancer (NSCLC). The clinical data of 1-, 2-, 3-, and 5-year actuarial or Kaplan-Meier TCP from 46 selected studies were collected for SBRT of NSCLC in the literature. The TCP data were separated for Stage T1 and T2 ...

Novalis powered by TrueBeam STx & BrainLab ExacTrac. Female patient 60 years with 2 column injuries L1 and T12 treated each with 2 dynamic arches, 10 MV photons and 20 Gy FFF 120 MicroMLC HD in 5 sessions.. Stereotactic Body Radiation Therapy is a therapeutic modality to manage, in a few sessions and with great precision, very high doses of radiation to the tumor effectively and with minimal toxicity to surrounding healthy tissue. Side effects are few. It is a treatment technique aimed at patients with tumors or metastases are inoperable and have injuries because of its location, cant be eradicated. The SBRT is a technique minimally invasive which allows the patient to receive treatment on an outpatient basis, without it is hospitalized.. The SBR requires precise planning to the target volume or target, since it is administered from different angles. This requires the use of 4 dimensional volumetric images mode, such as computed tomography (CT), taking into account the movement. These images ...

What is the COST Of Gamma Knife Radiosurgery in India: Why is Gamma Knife Radiosurgery so affordable Price? Know about the surgery and answers to FAQs at Spine and Neuro Surgery Hospital India.

Baehring JM, Hochberg FH. Primary Nervous System Tumors in Adults. In: Dariff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradleys Neurology in Clinical Practice . 7th ed. Philadelphia, PA: Elsevier; 2016:chap 74. Brown PD, Jaeckle K, Ballman KV, et al. Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases: a randomized clinical trial. JAMA . 2016;316(4):401-409. PMID: 27458945 www.ncbi.nlm.nih.gov/pubmed/27458945 . Elekta AB. Gamma Knife radiosurgery patient resource center. 2015. www.elekta.com/patients/gammaknife-treatment-process.html . Accessed August 9, 2016. Romanelli P, Morris DE, Adler JR Jr, Ewend MG. Image-guided robotic radiosurgery. In: Winn RH, ed. Youmans Neurological Surgery . 6th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 257. Welling DB, Spear SA, Packer MD. Stereotactic radiation treatment of benign tumors of the cranial base. In: Flint PW, Haughey BH, Lund V, Niparko JK, ...

Gamma knife surgery is very beneficial in treating many conditions which were considered to be non-treatable due to their life-threating effects or non-accessibility; such as small intracranial AVMs or cavernous angiomas; benign tumors including: acoustic neuromas, meningiomas, and pituitary adenomas craniopharyngiomas; tumors located at the base of the skull; metastatic brain lesions & other partially resected tumors; Parkinsons disease or other movement disorders, and many more.. There are many advantages of Gamma Knife Surgery in India over the traditional surgical procedure. This procedure is performed without incisions or general anesthesia, which reduces the risk of neurological deficit, infection, and bleeding. As a result, the recovery time is also reduced and they can get a normal life within days with little or no rehabilitative services. Another big advantage is after this treatment, patients require less chemotherapy interruption than standard radiation therapy. One of the important ...

TY - JOUR. T1 - Stereotactic body radiotherapy (SBRT) for oligometastatic lung tumors from colorectal cancer and other primary cancers in comparison with primary lung cancer. AU - Takeda, Atsuya. AU - Kunieda, Etsuo. AU - Ohashi, Toshio. AU - Aoki, Yousuke. AU - Koike, Naoyoshi. AU - Takeda, Toshiaki. PY - 2011/11. Y1 - 2011/11. N2 - Purpose: To analyze local control of oligometastatic lung tumors (OLTs) compared with that of primary lung cancer after stereotactic body radiotherapy (SBRT). Materials and methods: Retrospective record review of patients with OLTs who received SBRT with 50 Gy in 5 fractions. Local control rates (LCRs), toxicities, and factors of prognostic significance were assessed. Results: Twenty-one colorectal OLTs, 23 OLTs from other origins, and 188 primary lung cancers were included. Multivariate analysis revealed only tumor origin was prognostically significant (p , 0.05). The 1-year/2-year LCRs in colorectal OLTs and OLTs from other origins were 80%/72% and 94%/94%, ...

TY - JOUR. T1 - Analysis of suitable prescribed isodose line fitting to planning target volume in stereotactic body radiotherapy using dynamic conformal multiple arc therapy. AU - Oku, Yohei. AU - Takeda, Atsuya. AU - Kunieda, Etsuo. AU - Sudo, Yasunobu. AU - Oooka, Yoshikazu. AU - Aoki, Yousuke. AU - Shimouchi, Yoshiaki. AU - Nishina, Ryohei. AU - Nomura, Kazuhiro. AU - Sugiura, Madoka. AU - Ohashi, Toshio. N1 - Copyright: Copyright 2012 Elsevier B.V., All rights reserved.. PY - 2012/1. Y1 - 2012/1. N2 - Purpose: To assess the most suitable value of a relative prescribed dose in clinical treatment plans of stereotactic body radiotherapy (SBRT) using dynamic conformal multiple arc therapy to treat lung tumors. Methods and Materials: We retrospectively generated alternative SBRT plans for typical examples of 8 patients who had been treated with SBRT for a lung tumor with a prescribed dose of 50 Gy in 5 fractions. The prescribed dose had been defined as 80% of the maximal dose in the planning ...

Background: Although almost all dural arteriovenous fistulas (DAVFs) can be highly curable using endovascular treatment, some of them are reflactory. We evaluated the efficacy of stereotactic radiosurgery for DAVFs reflactory to endovascular treatment.. Methods: In 178 patients with DAVFs treated by endovascular embolization in our institution, 12 patients were reflactory and treated by CyberKnife (CK) radiosurgery. Patients background, efficacy of CyberKnife radiosurgery and complication were analyzed.. Results: 5 men and 7 women underwent CyberKnife radiosurgery. Ages ranged from 21 to 74 years (mean, 57.5 years). The locations of the fistulas were 10 transverse/sigmoid sinus and 2 cavernous sinus. The Borden classification was I in 3, II in 6, and III in 3 patients. Transarterial embolization (TAE) was performed in 10 patients, TAE and transvenous embolization (TVE) in 2. In all cases, shunt flow could be reduced, but small flow was residual. After embolization, residual fistula was treated ...

2. Lao L, Hope AJ, Maganti M, et al. Incidental prophylactic nodal irradiation and patterns of nodal relapse in inoperable early stage NSCLC patients treated with SBRT: A case-matched analysis. Int J Radiat Oncol Biol Phys 2014;90:209-215. 3. Timmerman R, Paulus R, Galvin J, et al. Stereotactic body radiation therapy for inoperable early stage lung cancer. JAMA2010;303:1070-1076. 4. Dunlap NE, Yang W, McIntosh A, et al. Computed tomographyebased anatomic assessment overestimates local tumor recurrence in patients with mass-like consolidation after stereotactic body radiotherapy for early-stage nonesmall cell lung cancer. Int J Radiat Oncol Biol Phys 2012;84:1071-1077. 5. Faruqi S, Guiliani ME, Raziee H, et al. Interrater reliability of the categorization of late radiographic changes after lung stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys 2014;89:10761083. 6. Timmerman R, Bastasch M, Saha D, et al. Optimizing dose and fractionation for stereotactic body radiation therapy. Normal

Purpose: : To evaluate the effectiveness of Leksell gamma knife treatment for choroidal melanoma not suitable for brachytherapy in terms of tumor control and resulting visual acuity. Methods: : Retrospective study of patients evaluated for uveal melanoma and found to be poor candidates for brachytherapy due to tumor thickness ,10 mm or proximity to optic disc. Patients who chose gamma knife over enucleation were referred for Leksell gamma knife where they received single fraction stereotactic radiation therapy of 20-25 Gy at the 50% isodose line. Follow-up was 2-77 months (mean = 34 months). Results: : In 11 of 12 (92%) patients, local control was achieved with tumor reduction. 1 patient died from metastatic disease. 3 of 12 (25%) patients had visual acuity better than 20/200 at last follow-up. Loss of visual acuity generally occurred due to radiation complications of therapy which were present in 8 of 12 (67%) patients. Conclusions: : Patients in this series had high rates of local control ...

Tagged: stereotactic ablative body radiation therapy. New Radiation Oncologist boosts skin and lung radiation capabilities, Stereotactic body radiation therapy plus chemotherapy improves survival, Lung Cancer and Radiation Therapy - Updates in Cancer Care Symposium Presentation, ARO selected as Australasian Training Site for Symmetry, Oligometastasis: a Curative Subset of Metastatic Disease, Extracranial Oligometastases: A Subset of Metastases Curable With Stereotactic Radiotherapy, Robotic image-guided reirradiation of lateral pelvic recurrences, Stereotactic radiation therapy in early stage NSCLC, New radiation therapy shows promise in lung cancer, Percutaneous spine stabilisation prior to stereotactic radiosurgery for high risk spinal metastases

TY - JOUR. T1 - Stereotactic Radiosurgery Versus Whole Brain Radiation Therapy. T2 - A Propensity Score Analysis and Predictors of Care for Patients With Brain Metastases From Breast Cancer. AU - Mainwaring, Walker. AU - Bowers, John. AU - Pham, Ngoc. AU - Pezzi, Todd. AU - Shukla, Mihir. AU - Bonnen, Mark. AU - Ludwig, Michelle. PY - 2019/4. Y1 - 2019/4. N2 - Background: Metastases to the brain occur in 10%-16% of patients with breast cancer, with incidence reportedly increasing. Historically, brain metastases (BM) have been treated with whole-brain radiation therapy (WBRT), but stereotactic radiosurgery (SRS) is an increasingly favored treatment option. In this study we used a population-level database to compare patterns of care and survival between WBRT and SRS for BM from breast cancer. Materials and Methods: The National Cancer Database was used to select patients treated with radiation for BM from primary breast cancer. Groups were classified on the basis of the modality of radiation ...

PRIMARY OBJECTIVES:. I. The primary goal of this study is to estimate the rate of grade 3 or higher acute toxicities observed during a 6 month period following CyberKnife radiosurgery for gynecologic cancers.. II. To evaluate clinical response to radio-surgery for gynecologic tumors.. III. To assess general and site specific quality of life (using SF-12, FACT-En, FACT-O, FACT-Cx or FACT-V) and to evaluate patients level of pain.. SECONDARY OBJECTIVES:. I. As a secondary objective, toxicities during the 2 years following CyberKnife radiosurgery will also be described.. OUTLINE:. Patients undergo 3 fractions of CyberKnife stereotactic radiosurgery.. After completion of study treatment, patients are followed at 1, 3, 6, 12, 18 and 24 months. ...

TY - JOUR. T1 - SU‐GG‐T‐537. T2 - Dosimetric Effect of Residual Tumor Motion in Phase and Amplitude‐Based Gated Lung Stereotactic Body Radiotherapy. AU - Zhao, B.. AU - Yang, Y.. AU - Heron, D.. AU - Huq, M.. PY - 2010. Y1 - 2010. N2 - Purpose To evaluate dosimetric effect of residual tumor motion in lung Stereotactic Body Radiotherapy(SBRT) with two gating methods using external markers: amplitude‐(AG) and phase‐based(PG). Methods and Materials The 3D tumor motion data were obtained from the treatment logs of 6 lung patients with various target size, each treated with 3 fractions of SBRT using Cyberknife Robotic Radiosurgical System and Synchrony™(Accuray, Sunnyvale CA). Amplitude and phase‐based gating treatments were simulated with a gating window of 5 mm. Planning target volume(PTV) was defined as physician‐contoured clinical target volume(CTV) surrounded by isotropic 5 mm margin. Each patient was prescribed with 60Gy/3fractions prescribed to 80% isodose line which covered ...

Advances in imaging and biological targeting have led to the development of stereotactic body radiation therapy (SBRT) as an alternative treatment of extracranial oligometastases. New radiobiological concepts, such as ceramide-induced endothelial apo

TY - JOUR. T1 - Stereotactic radiosurgery for hemangioblastomas of the brain. AU - Jawahar, A.. AU - Kondziolka, Douglas. AU - Garces, Y. I.. AU - Flickinger, J. C.. AU - Pollock, B. E.. AU - Lunsford, L. Dade. PY - 2000/6/27. Y1 - 2000/6/27. N2 - Objective. To assess the effectiveness of stereotactic radiosurgery in achieving tumor control and improving survival in patients with hemangioblastoma, we evaluated results from patients who were managed at the University of Pittsburgh and the Mayo Clinic. Patients and Methods. Twenty-seven patients with 29 hemangioblastomas had stereotactic radiosurgery over a 10 year interval. The mean patient age was 32 years (range, 14-75 years). The tumor volumes varied from 0.36 to 27 ml (mean, 3.2 ml), and the mean tumor margin dose was 16 Gy (range, 11.7-20). Clinical and neuroimaging follow-up was obtained for all patients between 0.5 and 9 years (mean, 4 years) after radiosurgery. Results. At this assessment, 21 patients (79%) were alive and six (21%) had ...

This protocol is a single arm phase II multi-center trial evaluating the efficacy of Stereotactic Body Radiation Therapy (SBRT) in patients with oligometastatic non-small cell lung cancer (NSCLC) with response or stable disease after 4 cycles of first-line chemotherapy. The core hypothesis tested is that SBRT after 4 cycles of first-line chemotherapy is feasible, safe, provides durable local control of treated lesions and improves time to progression compared to historical controls. Patients are eligible for enrollment if they have metastatic NSCLC with ≤5 lesions amenable to SBRT ...

BEIJING, February 5, 2018 - Elektas Leksell Gamma Knife® Icon™ radiosurgery system has received clearance from the China Food and Drug Administration (CFDA), enabling health care providers in the country to offer this advanced technology to their patients. With stereotactic imaging, automatic delivery correction and dose evaluation for ultra-precise dose delivery, as well as the availability of frameless treatments, Icon is capable of treating virtually any target in the brain, regardless of type, location or volume.

The effect of radiosurgery on spontaneous haemorrhage into metastatic brain tumours has not been sufficiently investigated. This study showed that haemorrhage was observed in 7.4% of patients (3.8% of tumours) before radiosurgery and in 18.5% of patients (7.6% of tumours) after radiosurgery. This would not necessarily imply that radiosurgery increases the likelihood of haemorrhage, as the incidence of intratumour haemorrhage is quite different between the early and later stages of brain metastases, which grow very rapidly. Rather, the incidence of haemorrhage after radiosurgery (18.5%) was no greater than that of untreated tumours reported previously (0-50%).3 However, it is not possible to state definitively whether radiosurgery increases, does not change, or decreases the risk of haemorrhage, because of the lack of a control group. However, 50% of the observed haemorrhages occurred within one month of the procedure. As most haemorrhagic tumours were under good local control at the time of the ...

Douglas Kondziolka, MD, a researcher and neurosurgeon at the NYU Langone Medical Center in New York City, who has performed many thousands of Gamma Knife procedures, said: Gamma Knife radiosurgery is an excellent example of how evolving cancer care technologies are addressing growing demand for precision medicine, where treatments can be precisely tailored to an individuals unique anatomy and biologic makeup while simultaneously helping to reduce the risk of damaging healthy tissue. As one of the most comprehensively studied tools in the neurosurgery armamentarium, we can confidently offer this treatment option as a minimally invasive alternative to traditional brain surgery or whole brain radiation therapy for properly selected patients.. Using up to 192 precisely focused sources of radiation, Gamma Knife can be used to control both malignant and nonmalignant tumors, as well as for treating arteriovenous malformations, essential tremor and trigeminal neuralgia while limiting damage to ...

Oligo-recurrence has been considered to confer improved prognosis than other oligometastatic conditions, and stereotactic body radiation therapy (SBRT) is considered as an option of local therapy for lung or liver metastases. The purpose of this study was to investigate the efficacy and safety of SBRT for lung and liver oligo-recurrent lesions and evaluate predictive factors for local control and prognosis. This retrospective study included patients who presented with 1-3 matachronous lung or liver metastases, and treated with SBRT between May 2013 and March 2016 at a single institution. All patients harbored a controlled primary lesion. Patients with | 6 months of follow-up were excluded. Local control, progression free survival, and overall survival rates were analyzed according to the Kaplan-Meier product limit method. Univariable log-rank and multivariable Cox regression analyses were performed to clarify predictive factors for local control and prognosis. Toxicity was graded according to the Common

To explore the association between biologically effective dose (BED) and survival rates in Child-Pugh A classification (CP-A) small hepatocellular carcinoma (HCC) patients treated with stereotactic body radiation therapy (SBRT). This retrospective study included 108 small HCC patients who were treated with SBRT between 2011 and 2014. The prescribed dose delivered to the tumor were 48Gy/8f, 49Gy/7f, 50Gy/5f and 54Gy/6f. The median biologically effective dose (BED10) of the total prescribed dose was 100Gy (76.8-102.6Gy). Factors associated with the survival rate were examined using the Cox proportion hazards model, and the factors associated with radiation-induced liver injury (RILD) were examined by logistic regression analysis. For these patients, the median follow-up time was 42 months (6-77 months), and the 1-, 2- and 3-year overall survival (OS) rates were 96.3, 89.8 and 80.6%, respectively. The 1-, 2- and 3-year progression-free survival (PFS) rates were 85.2, 70.1 and 60.6%, respectively. The 1-, 2

Object. In this study the authors sought to determine the neurological risks and potential clinical benefits of gamma knife radiosurgery for skull base meningiomas.. Methods. A consecutive series of 88 patients harboring skull base meningiomas were treated between 1990 and 1996 by using the Leksell gamma knife in a prospective clinical study that included a strict dose-volume protocol. Forty-nine patients had previously undergone surgery, and six had received external-beam radiotherapy. The median treatment volume was 10 cm3, and the median dose to the tumor margin was 16 Gy. The radiosurgical dosage to the optic nerve, the cavernous sinus, and Meckels cave was calculated and correlated with clinical outcome. The median patient follow-up time was 35 months (range 12-83 months).. Two tumors (2.3%) progressed after radiosurgery; the progression-free 5-year survival rate was 95%. At last follow-up review, 60 (68%) tumors were smaller and 26 (29.5%) remained unchanged. Clinical improvement (in ...

The purpose of this report was to review the results of stereotactic radiosurgery in the management of patients with residual neurocytomas after initial resection or biopsy procedures. Four patients underwent stereotactic radiosurgery for histologically proven neurocytoma. Clinical and imaging studies were performed to evaluate the response to treatment.. Radiosurgery was performed to deliver doses to the tumor margin of 14, 15, 16, and 20 Gy, depending on tumor volume and proximity to critical adjacent structures. More than 3 years later, imaging studies revealed significant reductions in tumor size. No new neurological deficits were identified at 53, 50, 42, and 38 months of follow up. The authors initial experience shows that stereotactic radiosurgery appears to be an effective treatment for neurocytoma. ...

TY - JOUR. T1 - A volumetric study of CyberKnife hypofractionated stereotactic radiotherapy as salvage for progressive malignant brain tumors. T2 - Initial experience. AU - Giller, Cole A.. AU - Berger, Brian D.. AU - Fink, Karen. AU - Bastian, Eleanor. PY - 2007/9/1. Y1 - 2007/9/1. N2 - Objective: Radiosurgery is frequently offered to patients with progressive malignant brain tumors if radiation therapy or chemotherapy fails to provide local control. The use of single-shot regimens, however, is limited by the risk of complications when the tumor is large, surrounded by edema or has been pre-treated with radiation. Hypofractionation may confer safety but has not been tested for these difficult tumors. We report the results of hypofractionation as an alternative option in a small cohort of progressive malignant brain tumors. Methods: Hypofractionated CyberKnife radiotherapy was chosen for 18 progressive malignant brain tumors (six high-grade gliomas and 12 metastatic lesions) in 15 patients ...

Patterns of failure after concurrent bevacizumab and hypofractionated stereotactic radiation therapy for recurrent high-grade glioma Academic Article ...

TY - JOUR. T1 - Toxicity profiles of fractionated radiotherapy, contemporary stereotactic radiosurgery, and transsphenoidal surgery in nonfunctioning pituitary macroadenomas. AU - Chang, Chia Lun. AU - Yuan, Kevin Sheng Po. AU - Wu, Alexander T.H.. AU - Wu, Szu Yuan. PY - 2019/11. Y1 - 2019/11. N2 - Background: Here, we compared the toxicity profiles of contemporary stereotactic radiosurgery (SRS), modern fractionated radiotherapy (FRT), and transsphenoidal surgery used to treat non functioning pituitary macroadenomas. Methods: We included the data of patients with non functioning pituitary macroadenomas. To compare treatment outcomes, the patients were categorized groups 1 (those receiving modern FRT), 2 (those receiving contemporary SRS), and 3 (those receiving transsphenoidal surgery). The multivariable Cox proportional hazards regression analysis was performed to yielded adjusted hazard ratios (aHRs) and their 95% CIs for local recurrence in groups 2 and 3 compared with group 1. Results: We ...

TY - JOUR. T1 - The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms. T2 - a systematic literature review. AU - Hernández-Durán, Silvia. AU - Hanft, Simon. AU - Komotar, Ricardo J. AU - Manzano, Glen. PY - 2015/7/30. Y1 - 2015/7/30. N2 - Advances in imaging technology and microsurgical techniques have made microsurgical resection the treatment of choice in cases of symptomatic intramedullary tumors. The use of stereotactic radiosurgery (SRS) for spinal tumors is a recent development, and its application to intramedullary lesions is debated. We conducted a literature search through PubMeds MeSH system, compiling information regarding intramedullary neoplasms treated by SRS. We compiled histology, tumor location and size, treatment modality, radiation dose, fractionation, radiation-induced complications, follow-up, and survival. Ten papers reporting on 52 patients with 70 tumors were identified. Metastatic lesions accounted for 33 %, while 67 % were ...

Stereotactic radiosurgery (SRS) has evolved as an accepted treatment for medication resistant trigeminal neuralgia. Initial results are very good but follow-up over three to five years shows a gradual return of pain in up to 50% of treated patients, often requiring further treatment. The results with repeat SRS using the isocentric Gamma Knife (GK) (Elekta, Stockholm, Sweden), especially in patients having initially good results, are very similar to the outcomes after the initial treatment although there is an increased risk of residual facial numbness secondary to the additional radiation dose to the trigeminal nerve. However, after 2000, non-isocentric SRS systems began to be used for treating trigeminal neuralgia including the CyberKnife (CK) (Accuray, Sunnyvale, California) as well as various linear accelerator (LINAC) based systems. This report specifically examines a series of recurrent trigeminal cases treated by the same group of physicians with the CK system. Similar doses and locations on the

Relevant Experience: CyberKnife Radiosurgery, Stereotactic Radiosurgery (SRS), Stereotactic Body Radiation Therapy (SBRT), Image-guided Radiation Therapy (IGRT), Intensity-Modulated Radiation Therapy (IMRT), Selective Internal Radiation Therapy (SIRT), High and Low-Dose Rate Brachytherapy for Prostate Cancer, Intracavitary High-Dose Rate Breast Brachytherapy, Intracavitary High-Dose Rate Brachytherapy for Gynecologic ...

Evidence-based recommendations on stereotactic radiosurgery using the gamma knife to treat trigeminal neuralgia (nerve pain in the face)

Quality of radiosurgery for single brain metastases with respect to treatment technology: a matched-pair analysis.Wowra B, Muacevic A, Tonn JC.European CyberKnife Center Munich, Max Lebsche Platz 31, Munich 81377, Germany. OBJECTIVE: ...

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Remarkable advances have been made in the treatment of lung cancer in recent years with the use of drugs aimed at therapeutic targets that have helped improve the prognosis of patients with disseminated disease. However, resectable lung tumors are being identified in increasing numbers of patients who cannot undergo surgery due to functional impairment, advanced age, or severe limiting comorbidities. Stereotactic body radiation therapy (SBRT) is a potentially curative alternative in the subgroup of patients with stage I lung cancers who are not candidates for surgery.1,2 SBRT uses a combination of fixed, reproducible anatomical structures as a reference for the administration of higher doses of radiation per fraction to the target lesion. For successful treatment and minimization of potential side effects, it is essential that the lesion is precisely identified. This underlying premise has supported the decision to implant fiducials within the tumor, as an essential preliminary step before ...

TY - JOUR. T1 - Radiographic response of brain metastasis after linear accelerator radiosurgery. AU - Rahman, Maryam. AU - Cox, J. Bridger. AU - Chi, Yueh Yun. AU - Carter, Jamal H.. AU - Friedman, William A.. PY - 2012/4/1. Y1 - 2012/4/1. N2 - Background: Radiographic response of brain metastasis to stereotactic radiosurgery (SRS) over time has not been well characterized. Being able to predict SRS-induced changes in tumor size over time may allow improved counseling of patients and potentially earlier recognition of poor response to SRS. Objective: To quantify the rate of change in size of metastatic brain tumors after treatment with a linear accelerator (LINAC) SRS. Methods: We performed a retrospective analysis of patients with single metastatic brain tumors treated with LINAC SRS at the University of Florida between 1992 and 2009 who had at least one MRI after treatment. A total of 218 patients with 406 follow-up MRI scans were included in the study. Tumor area was calculated by measuring ...

BackgroundStereotactic body radiotherapy (SBRT) demonstrates excellent local control in early stage lung cancer, however a quarter of patients develop recurrence or distant metastasis. Transforming growth factor-beta (TGF-β) supports metastasis and treatment resistance, and angiote...

At Yale-New Haven Hospital, the cranial SRS program has been operational since the 1990s. We are a large multidisciplinary program, treating over 300 gamma knife and 100 body radiotherapy cases per year. With the Gamma Knife® Perfexion unit and the Novalis TX radiosurgical platform, our practice encompasses a wide range of clinical situations, including complex intracranial, spine, lung, and liver body radiotherapy/radiosurgery. The Yale-New Haven Hospital has both the staff expertise as well as the breadth of clinical and technological experience available to provide a comprehensive fellowship opportunity. The goal of the fellowship is to provide the trainee with academic training in radiosurgery/body radiotherapy by participation in both the provision of clinical care and research in either clinical or basic science areas. The radiosurgery/body radiotherapy fellow is expected to train in all areas of SRS and SBRT. There will be significant opportunities for clinical research. The ...

There was no difference in clinical background between these groups. Complete response to therapy was noted in 29 (96.3%) patients of the SBRT group, and in only one (3.3%) patient of the TACE group (P , 0.001). None of the patients developed acute hematologic toxicity of more than Common Terminology Criteria for Adverse Events Grade 3 during and after the treatment. Furthermore, none of the SBRT group developed radiation-induced liver damage. Disease-free survival of the 12 patients without previous HCC treatments in SBRT group was significantly superior to that in control group (15.7 months vs 4.2 months; P = 0.029). ...

In 2017, Varians HyperArc™ high-definition radiotherapy was used for the first time to treat patients with brain metastases. This new technology for delivering noncoplanar stereotactic radiosurgery (SRS) has been deployed at Sacro Cuore Don Calabria Cancer Care Center in Negrar, near Verona, Italy; University of Alabama at Birmingham in the U.S.A..; and at The Beatson West of Scotland Cancer Center in Glasgow, U.K.

In 2017, Varians HyperArc™ high-definition radiotherapy was used for the first time to treat patients with brain metastases. This new technology for delivering noncoplanar stereotactic radiosurgery (SRS) has been deployed at Sacro Cuore Don Calabria Cancer Care Center in Negrar, near Verona, Italy; University of Alabama at Birmingham in the U.S.A..; and at The Beatson West of Scotland Cancer Center in Glasgow, U.K.

Background: To compare the effects of contemporary stereotactic radiosurgery (SRS), modern fractionated radiotherapy (FRT), and transsphenoidal surgery on nonfunctioning pituitary macroadenoma. Methods: We enrolled patients with nonfunctioning pituitary macroadenoma. To compare treatment outcomes, the patients were categorized into three groups according to the treatment modality: group 1, patients receiving modern FRT; group 2, patients receiving contemporary SRS; and group 3, patients receiving transsphenoidal surgery. Results: In total, 548 patients with nonfunctioning pituitary macroadenoma were selected for our study. Univariate and multivariate Cox regression analysis results indicated that the treatment modalities were significant independent prognostic factors. In multivariable Cox proportional hazard regression analysis, the adjusted hazard ratios (aHR; 95% confidence interval (CI)) of local recurrence were 0.27 (0.10–0.91) and 1.95 (1.25–2.37) for the SRS and transsphenoidal

The preradiosurgical annual hemorrhage rate was calculated as the number of hemorrhages divided by the patient-years at risk. Because AVM are generally considered as congenital anomalies, we assumed that patients were at risk for hemorrhage from their dates of birth. As an alternative metric, we also calculated the hemorrhage rate starting from the dates that AVM were diagnosed to the dates that AVM were treated. To calculate the annual rebleeding rate, the number of recurrent hemorrhages was divided by the total number of risk years from the dates of initial hemorrhage to the dates of GKS.. None of our patients had hemorrhage after the nidus was declared obliterated based on angiography; therefore, the postradiosurgical annual hemorrhage rate was calculated dividing the hemorrhagic events by the patient risk years from the dates of GKS to the dates that the AVM were judged to be obliterated on MRI or the dates of last follow-up if the nidi remained patent. We chose the dates that the AVM were ...

Gamma knife radiosurgical management of petroclival meningiomas results and indications.: Stereotactic radiosurgery with a Gamma knife provides effective manage

Neurosurgery: Brain angioma | Platinum coils embolization (coiling) or stereotactic radiosurgery. Treatment in Halle, Germany ✈ Find the best medical programs at BookingHealth - ✔Compare the prices ✔Online booking.

Brain angioma | Platinum coils embolization (coiling) or stereotactic radiosurgery. Neurosurgery: Treatment in Muenster, Germany ✈. Prices on BookingHealth.com - booking treatment online!

Dr. Gerszten serves as the Neurosurgical Principal Investigator of the National Cancer Institute Supported Radiation Therapy Oncology Group Cooperative Clinical Trial entitled Phase II/III Study of Single Dose Radiosurgery for Localized Spinal Metastases. Patient accrual into the Phase II trial was successfully completed this year and the published results are in press. Dr. Gerszten continues to investigate the expanding role of radiosurgery for the treatment of both malignant as well as benign disease. His work evaluating the successful use of cone beam computed tomography image guidance for spine radiosurgery for benign tumors was published this year. Ongoing research includes the incorporation of spine radiosurgery into minimally invasive and percutaneous spine procedures. Dr. Gersztens research related to spine radiosurgery is conducted in cooperation with the International Spine Oncology Study Group as well as the International Spine Radiosurgery Consortium. Current efforts include the ...

Munich, February 18, 2016-On February 19th-20th, international experts in radiation oncology and neurosurgery will come together for the Sixth International Conference of the Novalis Circle in Munich sponsored by global medical technology leader, Brainlab. The conference will serve as a forum for a cross-functional community, including radiation oncology and neurosurgery, to strategically address timely topics surrounding brain and spine cancer disease management.. Conference participants will focus on stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) for brain and spine across multidisciplinary cancer teams. Practice-oriented presentations and panel discussions revolve around five main clinical treatment areas: brain metastases, primary benign tumors, vascular malformations, spine tumors and new radiosurgery technologies. A total of 30 SRS and SBRT experts will present, including Douglas Kondziolka, MD, Jörg-Christian Tonn, MD, Reinhard Wurm, MD, Mark H. Bilsky, ...

Pictures by Shahiddan Saidi. CHERAS, 23 February 2017 - Hospital Chancellor Tuanku Muhriz, Universiti Kebangsaan Malaysia (UKM) is the first Government Agency to house a Gamma Knife Centre.. The treatment centre, built on the site of the built-up area of 4,000 square feet is valued at about RM25 million and is scheduled to be opened at the end of the year.. Minister of Health, Datuk S. Subramaniam said the radiosurgery treatment centre will benefit various types of patients, especially those who have abnormal lesions, cancerous and non-cancerous tumour.. Gamma Knife is a non-evasive neurosurgical procedure which uses powerful doses of radiation to target and treat tumours and abnormalities, shrinking them over time or stopping their growth.. With the centre, patients who have a tumour or brain cancer no longer have to undergo normal surgery, but they just need to do a treatment using Gamma Knife radiation, said Datuk S. Subramaniam.. This high-tech treatment focuses on specific brain tissue ...

Searching for the cost of Gamma Knife in Medellin? Contact Lyfboat to Get an Expert Second Opinion & Personalised Quote for Gamma Knife from the best Gamma Knife hospitals in Medellin. We enable patients to connect, communicate and find quality healthcare for Gamma Knife in Medellin.

The maximum deviation from the calculated target in any of the coordinates (x, y, z) was 2.1 mm and the mean deviation was 0.5 mm for x, 0.8 mm for y, and 1 mm for z. No lesion unintentionally encroached on an adjacent structure except the one that resulted in a homonymous hemianopsia. In that case the lesion eventually became much larger than expected, but the lesion center was initially at the intended target coordinates. DISCUSSION Several controversies exist in the field of functional stereotactic neurosurgery for movement disorders. These include the accuracy of stereotactic planning using MR imaging, the role of microelectrode recording in target localization, and the efficacy of pallidotomy and thalamotomy, among others. The current report addresses these and other controversial issues. Our prior reports show that MR imaging alone is sufficiently accurate to provide localization for stereotactic lesioning.[68-72] A number of authors have addressed the issue of magnetic field inhomogeneity ...

Nelsons syndrome (NS) is a long-term complication of bilateral adrenalectomy in patients with Cushings disease. The best therapeutic strategy

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In this randomised study, in patients with 4-10 brain metastases (BM), the standard treatment of whole brain radiotherapy (WBRT) is compared to …

In todays era, India has become the most coveted option for international patients who are looking for quality treatment, excellent services and hospitality at affordable price, due to which India is gaining immense popularity in field of medical tourism at global level. It is estimated that the cost of gamma knife surgery in India is almost half or less than half the cost of similar procedure in developed countries, which makes it highly advantageous for medical tourists. Many cities like Delhi, Mumbai, Bangalore , Pune ,Chennai( and many more) offer gamma knife radiosurgery and the hospitals which cater this treatment are well equipped with state of the art facilities and highly skilled and experienced health care professionals who not only treat the patients disease with greatest care and professionalism but also makes them feel at home ...

In todays era, India has become the most coveted option for international patients who are looking for quality treatment, excellent services and hospitality at affordable price, due to which India is gaining immense popularity in field of medical tourism at global level. It is estimated that the cost of gamma knife surgery in India is almost half or less than half the cost of similar procedure in developed countries, which makes it highly advantageous for medical tourists. Many cities like Delhi, Mumbai, Bangalore , Pune ,Chennai( and many more) offer gamma knife radiosurgery and the hospitals which cater this treatment are well equipped with state of the art facilities and highly skilled and experienced health care professionals who not only treat the patients disease with greatest care and professionalism but also makes them feel at home ...