Myint, PK, Luben, RN, Surtees, PG, Wainwright, NWJ, Wareham, NJ and Khaw, KT (2010) Physical health-related quality of life predicts the incidence of Coronary Heart Disease in the European Prospective Investigation into Cancer (EPIC) - Norfolk prospective population based study. International Journal of Epidemiology, 39 (4). pp. 996-1003. ISSN 1464-3685 Full text not available from this repository. (Request a copy ...
Both HRQoL and the prevalence of side effects were not statistically significantly different between screening and control groups whereas treatment choices between the two groups were statistically significantly different. The mean scores of sleeping and sexual dimensions of the 15D and the mean 15D scores of the screening population were statistically significantly lower in comparison with reference population. Treatment choices were associated with the prevalence of prostate-specific side effects, the sexual dimension of the 15D and overall HRQoL. Sex-related symptoms were the most common side effects and higher occurrence was observed in surgery patients. The presence of erectile side effects was associated with the sexual dimension of the 15D and overall HRQoL. However, other side effects were not found to be related to the three dimensions (sleeping, elimination and sexual activity) of the 15D or overall HRQoL. After adjusting for a number of factors, patients who experienced the worst ...
The Physical Quality of Life Index (PQLI) is an attempt to measure the quality of life or well-being of a country. The value is the average of three statistics: basic literacy rate, infant mortality, and life expectancy at age one, all equally weighted on a 0 to 100 scale.. It was developed for the Overseas Development Council in the mid-1970s by Morris David Morris, as one of a number of measures created due to dissatisfaction with the use of GNP as an indicator of development. PQLI might be regarded as an improvement but shares the general problems of measuring quality of life in a quantitative way. It has also been criticized because there is considerable overlap between infant mortality and life expectancy.[1]. The UN Human Development Index is a more widely used means of measuring well-being.. Steps to Calculate Physical Quality of Life:. 1) Find percentage of the population that is literate (literacy rate).. 2) Find the infant mortality rate. (out of 1000 births) INDEXED Infant Mortality ...
Post-procedure, patients remained hospitalized and were monitored for 24 to 48 h. Clinical follow-up was recommended at 3 months and annually. Before and after ablation at 3 months and 1, 2, and 3 years, patients received a questionnaire that included QoL assessment, symptom information, and self-reports of arrhythmia recurrences (and interventions) that occurred outside of follow-up visits. All reported outcomes were timed in relation to the patients last ablation at Mayo Clinic.. Health-related QoL was assessed with the Medical Outcomes Study Short Form-36 (SF-36). The SF-36 contains 8 individual scales, scored from 0 (worst health) to 100 (best health). Raw scores were presented as T scores in comparison with a healthy normal population with a mean score set at 50 with an SD of 10. In addition to a total score, physical component summary (PCS) and mental component summary (MCS) scores were assessed on a raw scale of 0 to 100 (14).. After August 2004, the Mayo AF-Specific Symptom Inventory ...
In a longitudinal study reported in the Journal of Clinical Oncology, Husson et al found that health-related quality of life improved between diagnosis and 2 years after diagnosis in adolescent/young adult (AYA) patients with cancer, but it remained impaired compared with population norms.. Study Details. The study involved 176 patients aged 15 to 39 years with various cancers from 5 U.S. institutions who completed the Short Form-36 Health Survey (SF-36) within 4 months after diagnosis and at 12 and 24 months later. The SF-36 summary physical component scale (PCS) and mental component scale (MCS) scores were converted to T scores ranging from 0 to 100, with a higher score indicating better health-related quality of life.. Changes Over Time. At baseline, AYA patients had significantly poorer mean PCS scores (38.7 vs 52.9, P , .001) and MCS scores (42.9 vs 48.9, P , .001) vs population norms (ages 18-40 years). AYA patients had significant improvements in PCS and MCS scores from baseline at 12 ...
The effects of physical activity on prescription (PAP) on health-related quality of life (HRQoL) in overweight adults are unclear. We therefore aimed to explore the effects of the Swedish PAP model on HRQoL in overweight older adults. Participants were recruited from a cohort of men and women born between 1937 and 1938, and living in Stockholm County. Inclusion criteria were; insufficiently physically active, i.e. |30 min of at least moderate intensity physical activity (PA) per day; body mass index |25 kg/m2; and waist circumference ≥102 cm (men) or ≥88 cm (women). Altogether, 101 individuals, aged 67 years, were randomly assigned to two parallel groups: intervention group (n = 47) receiving individualised PAP or control group (n = 54). The 36-item Short Form Health Survey (SF-36) was administered before and after the six months intervention. Main outcomes were the SF-36 physical component summary (PCS) and mental component summary (MCS) scores. Intention to treat analysis was utilised. Regression
Background Our aim was to investigate the existence of a reciprocal relationship between patients assessment of quality of life and their appraisal of health. If present, this relationship will interfere with the interpretation of heart surgerys effect on overall quality of life. Methods Path analysis was used to investigate reciprocal causal relationships between general health perceptions and overall quality of life before and after heart surgery. Longitudinal data from a study of coronary artery bypass surgery were used to model lagged, cross-lagged, and simultaneous paths over four time-points of assessment from before surgery to one year afterwards. The conceptual framework for the analysis was the Wilson and Cleary causal pathway model. General health perceptions were measured with the Short Form 36. Overall quality of life was measured with i) a single question regarding life satisfaction and ii) the multi-item Quality of Life Survey. Results Acceptable model fit was obtained for ...
Background: The EORTC 24971/TAX 323, a phase III study of 358 patients with unresectable locoregionally advanced squamous cell carcinoma of the head and neck, showed an improved progression-free and overall survival (OS) with less toxicity when docetaxel (T) was added to cisplatin and 5-fluorouracil (PF) for induction and given before radiotherapy (RT). The impact of the addition of docetaxel on patients health-related quality of life (HRQOL) and symptoms was investigated. Methods: HRQOL was assessed at baseline, at end of cycle 2, and 4, 6, and 9 months after completion of RT using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire C30 (QLQ-C30) and the EORTC QLQ Head and Neck Cancer-Specific Module (EORTC QLQ-H&N35). The primary HRQOL scale was global HRQOL per protocol. Results: Compliance to HRQOL assessments was 97% at baseline, but dropped to 54% by 6 months. Data were analysed up to 6 months. There was a trend towards improved global HRQOL ...
TY - JOUR. T1 - Impact of chronic gastrointestinal symptoms in diabetes mellitus on health-related quality of life. AU - Talley, Nicholas J.. AU - Young, Lisa. AU - Bytzer, Peter. AU - Hammer, Johann. AU - Leemon, Melanie. AU - Jones, Michael. AU - Horowitz, Michael. PY - 2001. Y1 - 2001. N2 - OBJECTIVES: Morbidity from GI symptoms in diabetes is considered to be high, but no studies have quantified the impact of GI symptoms in diabetes on health-related quality of life. We hypothesized that diabetics reporting increased GI symptoms would experience more impaired quality of life. METHODS: Subjects from the community with diabetes (n = 892) and outpatients with diabetes (n = 209) were recruited for this study. Subjects were divided into type 1 (diabetes diagnosed at age ,30 yr and requiring insulin) and type 2. A validated questionnaire measuring GI symptoms and diabetes status and the Short Form-36 were completed. The results were compared with Australian normal data. GI symptom groups measured ...
Research Team: Montse Ferrer, Jordi Alonso, Olatz Garin, Àngels Pont. The International health-related Quality of life Outcomes Database (IQOD) Group defines as general objective to develop a database of HRQL item responses, clinical and socio-demographic data from multiple sources of HRQL studies conducted throughout Europe; with the purpose of evaluating the psychometric properties of linguistically validated versions of three HRLQ instruments . The selected instruments were: The Womens Health Questionnaire (WHQ), the Psychological General Well-being Index (PGWB), and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Each of these instruments was selected for the IQOD project because of favourable reports of its reliability and validity, its linguistic adaptation into multiple European languages, and its extensive use throughout Europe and the US. However, the metric properties of these different versions have not been cross-culturally evaluated. The MLHFQ contains 2 domains ...
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Combined exposure to several healthy behaviors (HB) is associated with reduced mortality in older adults but its impact on health-related quality of life (HRQL) is uncertain. This is a cohort study of 2,388 individuals aged ≥60 recruited in 2000-2001, whose data were updated in 2003 and 2009. At baseline, participants reported both traditional HB (non-smoking, being very or moderately active, healthy diet) and non-traditional HB (sleeping 7-8 h/d, being seated <8 h/d, and seeing friends every day). HRQL was measured with the SF-36 questionnaire at baseline, in 2003 (short-term) and in 2009 (long-term); a higher score on the SF-36 represents better HRQL. Linear regression models were used to assess the association between HB at baseline and HRQL in 2003 and ...
The older Hispanic population of the U.S. is growing at a tremendous rate. While ethnic-related risk and complications of diabetes are widely-acknowledged for older Hispanics, less is known about how health related quality of life is affected in this population. Cross-sectional study assessing differences in health related quality of life between older Mexican Americans with and without diabetes. Participants (n = 619) from the Hispanic Established Population for the Epidemiological Study of the Elderly were interviewed in their homes. The primary measure was the Medical Outcomes Study Short Form (SF-36). The sample was 59.6% female with a mean age of 78.3 (SD = 5.2) years. 31.2% (n = 193) of the participants were identified with diabetes. Individuals with diabetes had significantly (F = 19.35, p | .001) lower scores on the Physical Composite scale (mean = 37.50, SD = 12.69) of the SF-36 compared to persons without diabetes (mean = 43.04, SD = 12.22). There was no significant difference between persons
International Journal of Hypertension is a peer-reviewed, Open Access journal that provides a forum for clinicians and basic scientists interested in blood pressure regulation and pathophysiology, as well as treatment and prevention of hypertension. The journal publishes original research articles, review articles, and clinical studies on the etiology and risk factors of hypertension, with a special focus on vascular biology, epidemiology, pediatric hypertension, and hypertensive nephropathy.
Do you ever feel like life is kicking you in the butt? Or do you ever feel like life is dragging you down? Though it may be hard preventing negativity from pulling you into a rut when you have a chronic condition, like hepatitis B, being more positive can help lift your spirits. When you do this, you can improve your health-related quality of life!. Though there is no set definition for health-related quality of life, the CDC defines it as an individuals or a groups perceived physical and mental health over time. Health related quality of life explains how a persons physical, emotional, mental and social aspects impact their overall life. Health-related quality of life can impact your overall well-being, which the CDC defines as "a positive outcome that is meaningful for people." Basically, improving health-related quality of life and overall well-being can help people feel that things are going well in their lives. Ultimately, this can help decrease stress and improve how well someone ...
Previous studies have shown that treatment-naïve HCV patients treated with RBV and IFN experience a significant PRO impairment.[13,14] In particular, the use of IFN causes substantial side effects, including debilitating ones such as severe depression, which, in turn, affect patients ability to sustain treatment long enough to obtain a cure whether through medical discontinuation or through patients nonadherence. The use of RBV also has been shown to decrease PROs during treatment. However, the PRO data in patients who are retreated after having experienced another course of treatment have not been reported. Therefore, the aim of this study was to evaluate PROs during treatment with and without the use of IFN in patients who participated in a prior study of an IFN-containing or an IFN-free DAA-based regimen and has not achieved SVR ...
TY - JOUR. T1 - Health-related quality of life. T2 - A guide for the health professional. AU - Nanda, Upasana. AU - Andresen, Elena. PY - 1998. Y1 - 1998. N2 - The importance of evaluating health care in terms of patients quality of life has only recently been acknowledged in the context of outcomes research and the measurement of quality of care. As a health professional, trying to choose the appropriate health status or health-related quality of life (HRQOL) measure can be daunting, as one is faced with a bewildering array of choices. The purpose of this article is to describe the process by which professionals might make a choice about measures in outcomes research. The article includes examples and rationale for using generic or disease- specific HRQOL measures. In addition, examples are provided of HRQOL assessment in two adult chronic disease applications: asthma and congestive heart failure.. AB - The importance of evaluating health care in terms of patients quality of life has only ...
The Medical Outcome Study Short Form 36-Item Health Survey (SF-36) is a self-administered questionnaire that measures the impact of disease on overall quality of life and consists of 36 questions in eight domains. The domains include physical (physical functioning, role limitations due to physical health (role-physical), general health perceptions and pain) and mental domains (energy/fatigue (vitality), social functioning, emotional well-being (mental health), and role limitations due to emotional problems (role emotional)). The individual domain scores are calculated and transformed to range from 0 to 100, with higher scores indicating a better level of functioning ...
The InterStim System is the Only Proven, Long-Term Sacral Neuromodulation Solution for Overactive Active Bladder. DUBLIN - July 17, 2017 - Medtronic plc (NYSE: MDT) today announced that the InterStim(TM) system, which provides sacral neuromodulation therapy, offers sustained long-term efficacy and quality of life improvements for overactive bladder (OAB) at five years.1 Results of the InSite study, which were published online in the Journal of Urology,1 found that 82 percent of patients had therapeutic success (defined as a greater than 50 percent improvement in symptoms) at five years and sustained quality of life improvements. "Effective long-term bladder control is critical because OAB is a chronic condition that significantly impacts all aspects of a persons quality of life, including confidence, activities and intimacy," said Steven Siegel, M.D., primary investigator and director, Metro Urology Centers for Female Urology and Continence Care, Minneapolis, Minn. "Many struggle to find ...
There is a growing interest to use quality of life as one of the dialysis outcome measurement. Based on the Malaysian National Renal Registry data on 15 participating sites, 1569 adult subjects who were alive at December 31, 2012, aged 18 years old and above were screened. Demographic and medical data of 1332 eligible subjects were collected during the administration of the short form of World Health Organization Quality of Life questionnaire (WHOQOL-BREF) in Malay, English, and Chinese language, respectively. The primary objective is to evaluate the quality of life among dialysis patients using WHOQOL-BREF. The secondary objective is to examine significant factors that affect quality of life score. Mean (SD) transformed quality of life scores were 56.2 (15.8), 59.8 (16.8), 58.2 (18.5), 59.5 (14.6), 61.0 (18.5) for (1) physical, (2) psychological, (3) social relations, (4) environment domains, and (5) combined overall quality of life and general health, respectively. Peritoneal dialysis group ...
TY - JOUR. T1 - Physical activity-related differences in body mass index and patient-reported quality of life in socioculturally diverse endometrial cancer survivors. AU - Rossi, Amerigo. AU - Garber, Carol Ewing. AU - Kaur, Gurpreet. AU - Xue, Xiaonan (Nan). AU - Goldberg, Gary L.. AU - Nevadunsky, Nicole S.. PY - 2017/2/16. Y1 - 2017/2/16. N2 - Purpose: The purpose of this study was to describe physical activity-related differences in body composition, quality of life, and behavioral variables among a socioculturally diverse sample of endometrial cancer survivors. Methods: Ambulatory, English-speaking endometrial cancer survivors (6 months to 5 years post-treatment), who were residents of Bronx, NY, were recruited to complete questionnaires about physical activity (PA), quality of life (QoL), and psychosocial characteristics. Body weight and height were obtained from medical records to determine body mass index (BMI). ANOVA and independent sample t tests were used to determine differences ...
BACKGROUND: After deep venous thrombosis (DVT), many patients have impaired quality of life (QOL). We aimed to assess whether pharmacomechanical catheter-directed thrombolysis (PCDT) improves short-term or long-term QOL in patients with proximal DVT and whether QOL is related to extent of DVT. METHODS: The Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTRACT) trial was an assessor-blinded randomized trial that compared PCDT with no PCDT in patients with DVT of the femoral, common femoral, or iliac veins. QOL was assessed at baseline and 1 month, 6 months, 12 months, 18 months, and 24 months using the Venous Insufficiency Epidemiological and Economic Study on Quality of Life/Symptoms (VEINES-QOL/Sym) disease-specific QOL measure and the 36-Item Short Form Health Survey (SF-36) physical component summary (PCS) and mental component summary general QOL measures. Change in QOL scores from baseline to assessment time were compared in the PCDT and no PCDT ...
Establishing predictors of quality of life (QoL) in individuals with inflammatory bowel disease could help to identify those patients who are most likely to experience poor quality of life.. It would then be possible to target therapeutic interventions appropriately.. Dr Welfare and colleagues undertook a study to investigate how disease-specific QoL depends on demographic, disease related, and physiological markers of disease activity, cognitive representations of illness, and perceived general health status.. The researchers collected a total of 111 Inflammatory Bowel Disease Questionnaires (IBDQ), Medical Outcomes Study 36-Item Short-Form Health Surveys (SF-36), and Illness Perception Questionnaires (IPQ).. The research team was able to determine the extent of disease from records, and disease activity by a symptom index.. The researchers used bivariate analyses and multivariate regression models to identify predictors of disease-specific quality of life.. ...
Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial. ...
DENVER, Oct. 18 "" Results from a University of Pittsburgh study evaluating intensity modulated radiation therapy (IMRT) for head and neck cancer determined the ideal doses for lessening treatment side effects. The findings were presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver. "Despite major advances in chemotherapy and radiation for the treatment of head and neck cancers, many patients continue to suffer debilitating side effects that greatly impact their quality of life," said Dwight E. Heron, M.D., study co-author and associate professor of radiation oncology, University of Pittsburgh School of Medicine and director of radiation oncology, University of Pittsburgh Medical Center. "While these high-energy beams are targeted to the tumor site as precisely as possible, they often inadvertently injure healthy tissue that surrounds the tumor site, limiting the doses of radiation that can be used to effectively destroy ...
The Life Quality Index (LQI) is a compound social indicator of human welfare that reflects the expected length of life in good health and enhancement of the quality of life through access to income. The Life Quality Index combines two primary social indicators: the expectancy of healthy life at birth, E, and the real gross domestic product per person, G, corrected for purchasing power parity as appropriate. Both are widely available and accurate statistics. The three components of the Life Quality Index, G, E and K reflect three important human concerns: the creation of wealth, the duration of life in good health and the time available to enjoy life. The amount of life available to enjoy wealth acts as a multiplying factor upon the value of that wealth. Conversely, the amount of income one has to enjoy that available lifetime acts as a multiplier on the expected duration of life. Unlike the United Nations Human Development Index (HDI), the LQI is derived rigorously from the economics of human ...
My name is Ruth Slattery. I am a sixty year old wife and mother of five sons all born at home.. I have always believed in a natural, whole foods approach to life. Having a degree in anthropology from the University of Texas at Austin made understanding and accepting the philosophy and science of the Perfect Health Diet by Paul Jaminet PHD and Shou-Ching Jaminet PHD logical and easy. The atmosphere and support at Albert Oaks makes the transition to a well rounded healthy lifestyle as easy as possible. The delicious meals by chef/owner Damon Young, oak covered grounds,chicken coop, orchard and beautiful vegetable gardens remind us of and attach us to the natural food and life experiences. Participants are encouraged to join in on caring for the chickens, gardening and cooking if interested. Personally I enjoy tending the chickens and gardening.. At Albert Oaks one learns the importance of proper light exposure, sleep, exercise and nutrition in acquiring and maintaining good health. ...
There appears to be a paradox in the prostate cancer literature: despite the fact that age and comorbidities are positively correlated, comorbidities are associated with worse physical and emotional quality of life while age is associated with worse physical quality of life but better emotional quality of life. Emotional support and positive reframing coping strategies may help explain part of this paradox in that they may be more frequently used by older prostate cancer patients and associated with better emotional quality of life. In an effort to better understand this paradox, the present questionnaire-based study of pre-treatment prostate cancer patients (n=74) investigated 1) the relations among age, comorbidity level, emotional quality of life, and physical quality of life, 2) age as a potential moderator of the association between comorbidities and emotional quality of life, and 3) an age-specific coping strategy comprised of emotional support and positive reframing as a mediator of the ...
There appears to be a paradox in the prostate cancer literature: despite the fact that age and comorbidities are positively correlated, comorbidities are associated with worse physical and emotional quality of life while age is associated with worse physical quality of life but better emotional quality of life. Emotional support and positive reframing coping strategies may help explain part of this paradox in that they may be more frequently used by older prostate cancer patients and associated with better emotional quality of life. In an effort to better understand this paradox, the present questionnaire-based study of pre-treatment prostate cancer patients (n=74) investigated 1) the relations among age, comorbidity level, emotional quality of life, and physical quality of life, 2) age as a potential moderator of the association between comorbidities and emotional quality of life, and 3) an age-specific coping strategy comprised of emotional support and positive reframing as a mediator of the ...
Background Chemotherapy treatment for metastatic breast cancer (MBC) has shown significant benefits in survival for breast cancer patients. However, chemotherapy is associated with several side effects that have a significant impact on patients quality of life. The objective of this analysis was to quantify the value patients with MBC place on reduced risk of treatment side effects.. Methods: A willingness to pay (WTP) survey was developed to assess metastatic breast cancer patients willingness to pay for a reduction in the risk of breast cancer treatment side effects. The survey assessed patients WTP for a 25%, 50% and 100% reduction in the risk of all side effects. Patients were also asked to select the side effect they would pay the most to avoid. Additionally, the survey collected demographic information such as treatment regimen, age, race/ethnicity, region, employment status, and insurance type.. Results: The survey was completed by 202 metastatic breast cancer patients. Most survey ...
Milwaukee, WI (PRWEB) May 25, 2017 -- A research study led by Drs. David Skaggs, Behrooz Akbarnia and Michael Vitale compared the health-related quality of
With increasing numbers of people suffering from a variety of orthopedic ailments, the use of orthopedic implants has become common. The surgeons use these implants for treatment of a wide range of bone related diseases such as fracture, several bone injuries, and joint pains. The surgeons replace the damaged bone and joint to give relief to the patient.. In India, manufacturers make and supply an entire range of orthopedic implants with high global quality standards ascertain. HEMC Ortho is one of the leading orthopedic implants manufacturers known for its quality production of a whole gamut of the implants. The company makes sure that each phase of the manufacturing takes place with global quality standards met. Implants such as rods, screws, pins, plates and host of others including the instruments are made in India and supplied to the domestic and overseas markets.. Types of implants used in orthopedic surgery There are many types of orthopedic implants. In fact, there are many implants used ...
Acpuris Intensive Spot Treatment - Get up-to-date information on Acpuris Intensive Spot Treatment side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Acpuris Intensive Spot Treatment
Health-related QOL was measured by mean changes from baseline in the EORTC-QLQ-C30 global health status/quality of life composite scale and by mean changes from baseline in the remaining EORTC QLQ-C30 questionnaire, Version 3. The EORTC QLQ-C30 is a questionnaire developed to assess the QOL of cancer patients. The questionnaire is a 30-item tool covering multiple items, including 5 functional scales (physical, role, emotional, social, and cognitive); 3 symptom scales (fatigue, nausea and vomiting, and pain); a global health status/QOL scale; and 6 single items (dyspnea, insomnia, appetite loss, constipation, diarrhea, and financial difficulties). Scores for each item range from 0 to 100. A high score for a functional scale represents a high (healthy) level of functioning, and a high score for the global health status represents a high QOL. However, a high score for a symptom scale represents more severe symptoms ...
Background: In order to assess and plan for changing healthcare needs, the lack of available information regarding temporal changes in the health-related quality of life of a population must be addressed. Aim: This paper aims to describe such changes over 5 years in a general population. Design of study: Longitudinal postal questionnaire study. Setting: UK general practice. Method: This was a longitudinal postal questionnaire study in two general practice populations, using the generic instalment EQ-5D to measure health-related quality of life. Individuals were included if they responded to three postal surveys in 1999, 2001, and 2004 and there were three consecutive values of EQ-5Dindex available between 1999 and 2004. Results: A total of 2498 subjects were included in the study. After adjustment for potential confounders (including ageing), health-related quality of life declined significantly over the observation period. The change in EQ-5Dindex was from 0.79 to 0.74 and for EQ-5Dvas 76.8 to ...
Chronic rhinosinusitis (CRS) is a common disorder with a significant impact on health-related quality of life (HRQL). Due to symptoms based diagnosis, disease severity is usually estimated using questionnaires which evaluate subjective scores on severity of symptoms and deterioration of HRQL, like Sino-Nasal Outcome Test-22 Questionnaire (SNOT-22). Objective severity staging is rather based on computerized tomography (CT) scores than on severity of inflammation. There is recent evidence that perceived stress has significant impact on asthma incidence and hospitalization, as well as on allergic rhinitis. As CRS is comorbidity of asthma and allergic rhinitis, we hypothesized that perceived stress may have impact on severity of CRS. The aim of the study is to correlate objective and subjective outcome measures with perceived stress. ...
IN PATIENTS WITH estrogen receptor-positive, HER2-negative advanced or metastatic breast cancer, better quality of life may be prolonged by delaying the progression of the disease, according to an ongoing quality-of-life assessment from the PALOMA-2 study, presented by Nadia Harbeck, MD, PhD, of the Breast Cancer Center at the University of Munich, Germany, and colleagues, at the 2017 European School of Oncology (ESO)/ European Society for Medical Oncology (ESMO) International Consensus Conference for Advanced Breast Cancer (ABC4) in Lisbon, Portugal.1 Analysis of trial data showed that patients whose disease took longer to progress had a significantly greater delay in the deterioration of health-related quality of life compared with patients whose disease progressed earlier, regardless of which treatment they had received. "This study is important because it shows for the first time that progression-free survival determination by imaging in a first-line clinical phase III trial indeed also ...
BC-CfE - Short term health-related quality of life improvement during opioid agonist treatment. - BACKGROUND:Opioid dependence is associated with high levels of morbidity, yet sparse data exists
Background Health-related quality of life (HRQoL) is widely used as an outcome measure in the evaluation of treatment interventions in patients with chronic obstructive pulmonary disease (COPD). In order to address challenges associated with existing fixed-length measures (e.g., too long to be used routinely, too short to ensure both content validity and reliability), a COPD-specific item bank (COPD-SIB) was developed. Methods Items were selected based on literature review and interviews with Dutch COPD patients, with a strong focus on both content validity and item comprehension. The psychometric quality of the item bank was evaluated using Mokken Scale Analysis and parametric Item Response Theory, using data of 666 COPD patients. Results The final item bank contains 46 items that form a strong scale, tapping into eight important themes that were identified based on literature review and patient interviews: Coping with disease/symptoms, adaptability; Autonomy; Anxiety about the course/end-state ...
Results The median disease duration was 7.5 (range 1-26) years in the WG group, and the median total VDI score was 2.0 (range 0-7). Compared to controls,WG patients reported impaired HRQOL reflected by significantly lower SF-36 physical component summary scores (PCS) and mental component summary scores (MCS) (p , 0.001) and by significantly lower scores in 7 out of 8 SF-36 subscales (p ≤ 0.001). In theWG group, no statistically significant correlations were found between the different SF-36 scores and the total VDI score, number of organ systems affected by damage, disease duration, or number of WG relapses. Patients with organ failure or other major forms of damage did not report significantly lower HRQOL than less severely affected patients. ...
Author(s): Kahn, Katherine L; Tisnado, Diana M; Adams, John L; Liu, Honghu; Chen, Wen-Pin; Hu, Fang Ashlee; Mangione, Carol M; Hays, Ronald D; Damberg, Cheryl L | Abstract: The validity of quality of care measurement has important implications for practicing clinicians, their patients, and all involved with health care delivery. We used empirical data from managed care patients enrolled in west coast physician organizations to test the hypothesis that observed changes in health-related quality of life across a 2.5-year window reflecting process of care.Patient self-report data as well as clinically detailed medical record review regarding 963 patients with chronic disease associated with managed care from three west coast states.Prospective cohort study of change in health-related quality of life scores across 30 months as measured by change in SF-12 physical component scores.Patient self-report and medical record abstraction.We found a positive relationship between better process scores and higher
To explore potential response shift effects with different quality of life (QoL) instruments in cardiac patients undergoing coronary intervention. Study Design and Setting: Recalibration was assessed with the disease specific health-related quality of life (HRQL) instrument MacNew in combination with a then-test approach. Reconceptualisation and reprioritisation were assessed with the individualised QoL instrument SEIQoL-DW. Significant treatment effects were seen on the MacNew (global Delta: 0.6 +/- 1.1, p = 0.004) but not on the SEIQoL-DW (Delta: 3.3 +/- 16, p = 0.37) 6 months after coronary intervention. No recalibration effect was found on the MacNew then-test, while with the SEIQOL-DW potential response shift effects of reconceptualisation and reprioritisation were seen. For the first time response shift effects were explored in cardiac patients undergoing coronary intervention. This study confirmed that there is a clinically significant improvement in disease specific HRQL over time ...
Aim: Advances in chemotherapy have significantly prolonged survival of patients with lymphoma and a significant percentage of patients may be cured. The assessment of the quality of life in patients undergoing chemotherapy is of growing interest. The aim of this study is to assess the effect of chemotherapy on quality of life in patients with lymphoma. Methods: All patients (n=49) diagnosed with stage I lymphoma in the Cukurova University Oncology Department from June 2000 to January 2001 received a quality-of-life questionnaire (EORTC QLQ C-30) before chemotherapy and after the second cycle of chemotherapy. Results: Significant improvement during treatment was found in some of the physical activities, emotional functioning, relieve from pain and fatigue, dyspnea, anorexia, sleep, and global quality of life. When chemotherapy, age, gender and lymphoma type were taken into account, the most important factor influencing the global quality of life was educational status. Conclusion: The results may ...
A head-to-head trial evaluated quality of life improvements in patients with moderate-to-severe psoriasis treated with secukinumab (Cosentyx) or ustekinumab (Stelara).
TY - JOUR. T1 - Validation of the WHO-5 well-being index in adolescents with type 1 diabetes. AU - De Wit, Maartie. AU - Pouwer, Frans. AU - Gemke, Reinoud J.B.J.. AU - Delemarre-Van De Waal, Henriette A.. AU - Snoek, Frank J.. PY - 2007/8/1. Y1 - 2007/8/1. N2 - OBJECTIVE - It is recommended that the psychological status of adolescents with diabetes be assessed periodically as part of ongoing care. The World Health Organization-Five Well-Being Index (WHO-5) is a short self-report instrument that appears suitable for this purpose. This study is the first to assess the reliability and validity of the WHO-5 in adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS - Ninety-one adolescents with type 1 diabetes (aged 13-17 years) from four pediatric clinics completed the WHO-5, along with other psychological measures: the Center for Epidemiologic Studies Depression Scale (CES-D), the Diabetes Family Conflict Scale (DFCS), and the mental health and self-esteem subscales of the Child Health ...
Purpose To present the impact of treatment on health-related quality-of-life (HRQOL) and health utility measures from the randomized controlled trial (ClinicalTrials.gov Identifier: NCT02398721) that...
The objective of this study is to compare health-related quality of life (QOL) outcomes between radical prostatectomy (RP) and external beam radiation therapy (EBRT) for localized prostate cancer. PubMed, EMBASE, the Cochrane Library and Web of Science (to July 2017) were searched. Pooled analysis of each domain-specific score was calculated in relevant studies, and its change with follow-up time was explored by sub-group analysis. A total of six studies containing 4423 patients were included. Men underwent RP was associated with worse urinary and sexual domain score than EBRT (standardized mean difference (SMD) = -0 ...
The team found that general health status, measured by the Short Form-36 questionnaire, was worse in the constipated vs non-constipated populations.. Results were comparable in all countries.. The research team observed that quality of life scores correlated negatively with age.. The team noted that constipated women reported more impaired health related quality of life than constipated men.. People from Brazil were most affected by constipation as to their social functioning and general health perception.. Dr Petrinis team concludes, "There are significant differences in health related quality of life between constipated and non-constipated individuals.". "We found a significant, negative correlation between the number of symptoms and complaints and Short Form-36 scores.". "The study detected a correlation of constipation with quality of life and the influence of social and demographic factors on health related quality of life in constipated people.". ...
Patient-reported health-related quality of life (Hr-QoL) is an essential end-point to assess the efficacy of multiple sclerosis (MS) treatment. Most QoL tools were developed for clinical research, for which measurement accuracy is required, irrespective of ease of use or the human resources needed. In routine medical practice (RMP), time and resources are limited, requiring simple and quick tools. Our objective was to set up a Hr-QoL measurement adapted for patients with MS, and providing an accurate estimate of Hr-QoL, whilst remaining easy to use and interpret in the RMP context. ...
Background: Pulmonary function is severely reduced in the early period after cardiac surgery, and impairments have been described up to 4-6 months after surgery. Evaluation of pulmonary function in a longer perspective is lacking. In this prospective study pulmonary function and health-related quality of life were investigated 1 year after cardiac surgery.. Methods: Pulmonary function measurements, health-related quality of life (SF-36), dyspnoea, subjective breathing and coughing ability and pain were evaluated before and 1 year after surgery in 150 patients undergoing coronary artery bypass grafting, valve surgery or combined surgery.. Results: One year after surgery the forced vital capacity and forced expiratory volume in 1 s were significantly decreased (by 4-5 %) compared to preoperative values (p , 0.05). Saturation of peripheral oxygen was unchanged 1 year postoperatively compared to baseline. A significantly improved health-related quality of life was found 1 year after surgery, with ...
OK, here goes! I was told from my Dr to buy your book. After my bloodwork came back, she told me I had an infection in my body and this book would change my life. This was just less then 1 week ago. I read the book in one sitting, and was naturally very excited to get well. My back story…I have had HBP since the first time it was taken at age 18. I never weighed more than 130 pounds at 58″, so I never worried about what I ate, until I became toxemic with my first child at age 22. I read every label, making sure not to eat anything with added salt. At 27, I was on a beta blocker and taken off, because of my good work with eating no salt and exercise. I weighed 130-135 my whole life until I became extremely dehydrated, had thrush in my mouth and throat and was hospitalized at age 48. I was on medications, including attenolol with hctz, and was being treated for fibomalagia with soma and tramadol. Bloodwork and tests came back in the hospital that I had CKD, barely any vitamin c, b 12 and ...
Background In patients with suspected coronary artery disease (CAD), the overall aim was to analyse the relationships between disease severity and both mental and physical dimensions of health related quality of life (HRQOL) using a modified version of the Wilson and Cleary model. Methods Using a cross-sectional design, 753 patients (74% men), mean age 62 years, referred for elective cardiac catheterisation were included. The measures included 1) physiological factors 2) symptoms (disease severity, self-reported symptoms, anxiety and depression 3) self-reported functional status, 4) coping, 5) perceived disease burden, 6) general health perception and 7) overall quality of life. To analyse relationships, we performed linear and ordinal logistic regressions. Results CAD and left ventricular ejection fraction (LVEF) were significantly associated with symptoms of angina pectoris and dyspnea. CAD was not related to symptoms of anxiety and depression, but less depression was found in patients with ...
PAKPOUR, A. H., YEKANINEJAD, M., MOLSTED, S., HARRISON, A. P., HASHEMI, F. and SAFFARI, M. (2011), Translation, cultural adaptation assessment, and both validity and reliability testing of the Kidney Disease Quality of Life - Short Form version 1.3 for use with Iranian patients. Nephrology, 16: 106-112. doi: 10.1111/j.1440-1797.2010.01389.x ...
Objective To determine factors associated with work in patients with ankylosing spondylitis (AS). Methods Three hundred fifteen patients with AS were enrolled in a 24-week, randomized controlled study of adalimumab with a longterm, open-label, adalimumab extension phase. Patient-reported outcome (PRO) measures included the Medical Outcome Study Short Form 36 Health Survey (SF-36), AS Quality of Life Questionnaire (ASQOL), Health Utilities Index Mark 3 (HUI-3), and Work Productivity and Activity Impairment-Specific Health Problem Questionnaire (WPAI-SHP). Multivariate logistic regression was used to analyze differences between working and nonworking patients. The relationships between PRO and WPAI-SHP scores were assessed using Pearson correlation coefficients. Multivariate modeling was applied to determine factors associated with productivity while at work. WPAI-SHP was assessed through 3 years of adalimumab exposure. Results Younger age (p = 0.002) and male sex (p , 0.001) were significantly ...
4 Perfect Health Vitamins Reviews and other Reviews of Nutritional Supplements and Merchants Plus Related Resources Including a 2018 Buying Guide. Healthy Learning for Healthy Living.
TY - JOUR. T1 - State of the science in ovarian cancer quality of life research. T2 - A systematic review. AU - Hess, Lisa M.. AU - Stehman, Frederick B.. PY - 2012/9/1. Y1 - 2012/9/1. N2 - Introduction: Health-related quality of life (HRQOL) has become an increasingly important focus of outcomes in cancer care with the movement toward more patient-oriented research. Quality-of-life outcomes are important in ovarian cancer, which has not yet benefitted from improved survival outcomes as have other diseases. This study was designed to systematically assess and summarize HRQOL in ovarian cancer. Methods: A systematic search strategy was initiated to identify published literature measuring HRQOL of women with a diagnosis of ovarian cancer (OC). Data were synthesized to evaluate HRQOL and patient-reported outcome data at various time points: before, during, and after chemotherapy. Data were pooled and summary statistics compared across published studies. Comparisons of means were conducted using ...
Results Overall 216 patients were included (n=86, tofacitinib 5 mg BID; n=86, tofacitinib 10 mg BID; n=22, PBO→tofacitinib 5 mg BID; n=22, PBO→tofacitinib 10 mg BID). There were no major differences in demographics or baseline characteristics between treatment groups. At Month 3, tofacitinib resulted in significantly greater changes in HAQ-DI (5 mg BID, p,0.05; 10 mg BID, p,0.001), PtGA (5 mg BID, p,0.05; 10 mg BID, p,0.001), Pain (5 mg BID, p,0.001; 10 mg BID, p,0.001) and SF-36 Physical Component Summary (PCS) scores (5 mg BID, p,0.05; 10 mg BID, p,0.001) vs PBO (Figure). Numeric improvements in FACIT-Fatigue, SF-36 Mental Component Summary (MCS) [Figure] and EQ-5D health state profile (utility scores) were observed at Month 3 with tofacitinib vs PBO. There were no improvements in WLQ observed at Month 3 with tofacitinib vs PBO. Improvements were generally maintained at 6 and 12 months (Figure). The proportion of patients achieving HAQ-DI improvement ≥0.22 from baseline at Month 3 was ...
Although health-related quality of life (HRQOL) is diminished in HCV/HIV, the relationship between virologic response and maintenance therapy with HRQOL in this population is unknown. ACTG 5178 was a phase 2, randomized trial, with three steps - Step 1: all subjects received pegylated interferon (PEG-IFN)/ribavirin (P/R) for 12 weeks. Step 2: subjects who failed to achieve early viral response (EVR) were randomized to PEG-IFN or observational control for an additional 72 weeks. Step 3: subjects with EVR from step 1 continued on P/R for a total of 72 weeks with 24 weeks follow-up off-therapy. HRQOL, symptom distress and depression levels were measured at multiple time points. In step 1 (n = 329), there was a significant decline in HRQOL in all dimensions. In step 3 (n = 169), the overall HRQOL and three of its eight dimensions (general health, role function and pain score) were increased, and achievement of sustained virologic response was associated with increased general health and cognitive ...
An accurate, sensitive, but brief quality-of-life outcomes measure is needed for studies of dermatologic care. To construct a single-page version of Skindex (a dermatologic quality-of-life instrument)
There were no significant interaction effects for five objective cognitive function tasks suggesting that changes over time were not due to group membership. However, psychomotor function (controlling for age) and physical well-being were significantly worse for the chemotherapy versus the surgery group at baseline, with groups converging by follow-up. Groups showed no differences in subjective cognitive dysfunction. The chemotherapy group showed higher anxiety, poorer functional well-being and worse fatigue compared to the surgery-only group at baseline, but not by follow-up. For both groups, emotional well-being, functional well-being and anxiety significantly improved over time.. ...
Although a substantial body of literature has provided evidence supporting the positive effects of natural environments on well-being, little has been known about the specific spatial patterns of urban nature in promoting health-related quality of life (HRQOL) among children. This study assessed the association that the urban natural environment measured by landscape spatial patterns may have with obesity and HRQOL among Hispanic children. Ninety-two 4th and 5th grade students were recruited from Houston, Texas, and the Pediatric Quality of Life Inventory (PedsQL) was used to capture the childrens HRQOL. The quality of urban natural environments was assessed by quantifying the landscape spatial patterns, using landscape indices generated by Geographic Information Systems and remote sensing. From the bivariate analyses, childrens body mass index showed a significantly negative association with their HRQOL. After controlling for socio-demographic factors, the results revealed that larger and more tree
Several assumptions of the indirect reflective model of the Multidimensional Students Life Satisfaction Scale (MSLSS) were tested to assess its validity as a measure of adolescents satisfaction with life generally and with five important life domains (family, friends, living environment, school, and self perception). We also examined whether adolescents perceived mental and physical health status significantly explained their global quality of life (QOL) and whether these relationships were mediated by their satisfaction with the five life domains. The data were taken from a cross-sectional health survey of 8,225 adolescents in 49 schools in British Columbia, Canada. Global QOL was measured using Cantrils ladder and a single-item rating of the adolescents satisfaction with their QOL. Confirmatory factor and factor mixture analyses were used to examine the measurement assumptions of the MSLSS, and structural equation modeling was applied to test the hypothesized mediation model. The Pratt ...
TY - JOUR. T1 - The adaptations of a quality of life questionnaire for routine use in clinical practice: the Chronic Respiratory Disease Questionnaire in cystic fibrosis. AU - Bradley, Judy. AU - Dempster, M. AU - Wallace, Eric. AU - Elborn, S. PY - 1999. Y1 - 1999. M3 - Article. VL - 8. SP - 65. EP - 71. JO - Quality of Life Research. T2 - Quality of Life Research. JF - Quality of Life Research. SN - 0962-9343. IS - 1-2. ER - ...
Background Health-related quality of life (HRQoL) is increasingly recognised as an important patient-reported outcome in health care research. However, the use is still restricted and several questions remain about the value and feasibility of using measures of HRQoL in routine health care. The general aims of the thesis were therefore to increase the understanding of these issues by studying 1) associations of HRQoL with psychological and biological factors, 2) comorbidity adjustments of HRQoL measurement results, and 3) the patient-perceived value and feasibility regarding the use of measures of HRQoL as patient-reported outcome in routine health care.. Methods Three different data sets were used; baseline data (questionnaire, anthropometric, and biological) from the ongoing Life conditions, Stress, and Health Study (n=1007, papers I and II), data from a population survey from the County Council of Östergötland in combination with data from two national Swedish registries, the National ...
|p||i|Health and Quality of Life Outcomes|/i| is an open access, peer-reviewed, online journal offering high quality articles, rapid publication and wide diffusion in the public domain.|/p||p||i|Health and Quality of Life Outcomes|/i| considers original manuscripts on the Health-Related Quality of Life (HRQOL) assessment for evaluation of medical and psychosocial interventions. It also considers approaches and studies on psychometric properties of HRQOL and patient reported outcome measures, including cultural validation of instruments if they provide information about the impact of interventions.|/p|
BACKGROUND: Evidence is growing on the benefit of physical activity to improve well-being following a cancer diagnosis. This study examined changes in physical activity from pre to post diagnosis and explored this relationship with quality of life and depression. METHODS: Participants were recruited by posters and by letter of invitation. The questionnaire was completed by 59 prostate and 32 breast cancer survivors. RESULTS: Physical activity decreased by 72 minutes per week from pre to post diagnosis, although 20.9% reported having increased activity post diagnosis. Over 30% were considered depressed. Breast cancer participants who increased physical activity post diagnosis reported higher scores for Physical Wellbeing subscale (26 versus 21; F[1,29] = 5.19, p , .03), Emotional Wellbeing subscale (22 versus 19; F[1,30] = 4.57, p , .04) and Functional Wellbeing subscale (26 versus 19; F[1,30] = 9.03, p , .001). A greater proportion of participants taking part in no physical activity were ...
COSMED USA, Inc. announces the recently completed acquisition of Life Measurement, Inc. (LMI), a leading provider of body composition assessment equipment in infants, children and adults. LMI...
Post a Comment for Evaluation of two health related quality of life instruments for use with older African Americans with diabetes mellitus Gayenell Smith Magwood. ...
Test care models that coordinate benefits for dual-eligibles are lacking in quality-of-life measures, which are essential to identifying effective innovations, concludes a new policybrieffrom The Commonwealth Fund.
BACKGROUND: Multiple sclerosis (MS) is a chronic neurological disorder, which can lead to a wide range of disabling symptoms. The condition has a significant negative impact on health-related quality of life, and the economic cost of the disease is substantial. Decision-making regarding treatments for MS, and particularly disease-modifying interventions, has been hampered by limitations in the data and evaluative framework for assessing their cost effectiveness. Whilst attention has been drawn to these weaknesses, the scope and extent of the challenges in this area have not been fully set out to date. AIMS: the aims of this review were to identify all published economic evaluations of MS treatments in order to provide a statement on the scope and characteristics of the cost-effectiveness literature in the area of MS and to provide a basis on which to suggest practical recommendations for future research to aid decision-making. METHOD: a systematic search was undertaken to identify economic ...
Biology Assignment Help, Evolution, Evolution can be explained as follows 1) The change in the life over time by adaptation, over-reproduction, variation and differential survival/reproduction, a procedure referred to by Charles Darwin and Alfred Wallace as the natural selection.
Purpose: This study aimed to identify the predictors of decline in health-related quality of life (HRQOL) in Chinese patients with type 2 diabetes mellitus (T2DM). Methods: A prospective longitudinal observational study was conducted on 1826 Chinese T2DM patients managed in public primary care setting. HRQOL was measured at baseline, 1 and 2 years by the Short Form-12 Health Survey version 2 (SF-12v2) and Chinese (HK) Short Form-6 Dimensions (SF-6D). Linear mixed effect models with forward stepwise method were performed to select the factors associated with SF-12v2 physical (PCS) and mental component summary (MCS) scores and SF-6D value. Results: Over a 2-year observation period, the HRQOL (PCS: −0.626; MCS: −1.869; and SF-6D: −0.017 per year) scores decreased significantly with time. Female, unmarried, current smoker, no regular exercise, obesity, comorbid hypertension, chronic kidney disease (CKD) or cardiovascular disease (CVD) and insulin use were predictors of one or more poorer HRQOL ...
This statistic shows the well-being index of China in 2014, broken down into five segments, namely purpose, social, financial, community and physical well-being.
The Foundation continues its initiative to monitor and report on living conditions and quality of life in Europe. 28-country Quality of life in Europe survey The European quality of life survey (EQLS) that was carried out in 2003 covered 28 countries and involved interviewing 26,000 people. The survey examined a range of issues, such as employment, income, education,
The Foundation continues its initiative to monitor and report on living conditions and quality of life in Europe. 28-country Quality of life in Europe survey The European quality of life survey (EQLS) that was carried out in 2003 covered 28 countries and involved interviewing 26,000 people. The survey examined a range of issues, such as employment, income, education,
Introduction The health-related quality-of-life (HRQoL) instruments are an important tool for the evaluation of medical outcomes. Sexually transmitted diseases (STDs) influence the patients life. We...
SILVEIRA, Augusta et al. Head and Neck Cancer: Health Related Quality of Life Assessment considering clinical and epidemiological perspectives. Rev. bras. epidemiol. [online]. 2012, vol.15, n.1, pp.38-48. ISSN 1415-790X. http://dx.doi.org/10.1590/S1415-790X2012000100004.. The importance of oncology diseases as a cause of morbidity and mortality is increasing worldwide, and their social impact is being recognized due to economic and social costs involved in prevention, treatment and rehabilitation. Head and neck cancer is one of the six most prevalent neoplasms worldwide, with an estimated 900,000 new cases diagnosed annually. Regardless of tumor site, deterioration of basic functions affecting head and neck areas are perceived and affect patients lives. Appropriate cancer registration may provide a better analysis of health-related quality of life outcomes. In this study, 380 head and neck cancer patients were evaluated. The study showed that women have lower overall Quality of Life results. It ...
To describe the development of a proctitis-specific quality-of-life module to supplement the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). The module was developed according to EORTC guidelines, which consisted of an extensive literature review to identify previously described issues and interviews conducted with seven health professionals and 10 patients to rationalize the item list for construction into a provisional module. The module developed was then pretested with 28 patients and five health professionals. The final module contains 21-items that are suitable to obtain information about the patients quality of life after high-dose pelvic irradiation. The questionnaire has now been translated into four languages and commenced field testing in late 2007. The EORTC QLQ-C30, supplemented by EORTC QLQ-PRT21, will enable health professionals to more accurately monitor the side effects that patients experience after pelvic ...
BACKGROUND AND OBJECTIVE: To be useful, results from health-related quality of life (HRQoL) measures must be interpretable. The objective of this article is to examine statistical (distributional) approaches to interpretability. The standard error of measurement (SEM) and the standard error of the difference (S(diff)) are used in data on individuals with Parkinsons disease to calculate the minimum change scores required to be statistically meaningful for each dimension of an instrument to assess HRQoL in Parkinsons disease, the PDQ-39. METHODS: Data was collected from both a community and a clinic study; in both studies the PDQ-39 was administered at baseline and follow-up. RESULTS: The patterns of SEMs and S(diff)s were similar both across time periods and between samples, for all dimensions except Social Support. CONCLUSIONS: The results suggest that, for example, six points change on a 0-100 transformed scoring of the Mobility dimension may be considered on distributional grounds a minimum
OBJECTIVES By the end of Word War II, a substantial proportion of the German population was subjected to flight and expulsion. Severe strain and traumatization were described in individual reports. Preliminary studies based on selected samples indicated profound long-term consequences but no representative studies have been carried out to date. The purposes of the present study were to compare quality of life and well-being of former refugees and non-refugees and to identify risk factors for compromised well-being. METHODS A representative sample of the German population (N = 2.043) was interviewed about experiences of flight and expulsion and their present quality of life. RESULTS The refugees (18 % of the respective age group; N = 133) reported a reduced physical quality of life at the time of the study (SF-36). Furthermore, they suffered more often from panic attacks and were compromised in their health and well-being. In the regression analysis, the status as a former refugee was predictive for
Quality-of-life assessment of morbidly obese patients who have undergone a Lap-Band operation: 2-year follow-up study. Is the MOS SF-36 a useful instrument to measure quality of life in morbidly obese patients ...
BiblioPRO is a virtual library of Quality of Life Questionnaires and other Patient Reported Outcomes (PROs) in Spanish with free and open access.. The mission of our project is to promote the adequate use of HRQL instruments in Spanish among researchers, clinicians and health management, by providing exhaustive online information, evidence-based evaluations, and specialized training in this area.. The library currently holds information on over 500 questionnaires and is updated periodically.. BiblioPRO is a CIBER in epidemiology and public health Research and Knowledge Transfer Support Action, iniciated, directed coordinated by the Health Services Research Unit of the IMIM (Hospital del Mar Medical Research Institute), with the IMIM Foundation support.. To accés BiblioPRO click here .. ...
Background: Studies examining the impact of injury on health-related quality of life (HRQL) over time are necessary to understand the short-and long-Term consequences of injury for population health. The aim of this systematic review was to provide an evidence update on studies that have measured HRQL over time in general injury populations using a generic (general) health state measure. Methods: Studies conducted between 2010 and 2018 that assessed HRQL at more than one time point among general injury populations were eligible for inclusion. Two reviewers independently extracted information from each study on design, HRQL measure used, method of HRQL measure administration, timing of assessment(s), predictive variables, ability to detect change, and findings. Quality appraisals of each study were also completed by two reviewers using items from the RTI Item Bank on Risk of Bias and Precision of Observational Studies and the Guidelines for the Conduction of Follow-up Studies Measuring ...
The minimal important difference MID is the smallest benefit of treatment that would result in clinicians recommending it to their patients. The MID is necessary to calculate sample size for randomized clinical trials, but its chosen value is often arbitrary. This study set out to determine the practicability of surveying physicians to elicit...
Cancer treatments such as chemotherapy, radiation therapy and prostate surgery may affect a mans sexual function, lower libido, and make it difficult to get an erection. Learn how to manage and treat these sexual problems, during cancer treatment.
The arguments for assessing health-related quality of life (QoL) in children undergoing medical treatment are persuasive. Consideration of QoL places the child at the centre of the assessment, and emphasises the autonomy of the family in decision-making. Over-reliance on physiological indices neglects the important question of how illness or treatment impacts on childrens own ratings of their health or well-being. However, assessment of QoL, especially in paediatrics, has proved challenging, and there remain many questions about whether or not it is possible to measure a concept as subjective as QoL, and indeed what could be gained beyond the traditional assessment of outcomes. Perhaps any new undertaking is inevitably associated with considerable pain. It seems timely to assess whether the anticipated gains (increased awareness of childrens views and improved communication) have been achieved. This is not a comprehensive review of the literature, but where possible, arguments are illustrated ...
Treatment-related complications are common in breast cancer patients long after their therapy has been completed, a new study says.
BackgroundThe quality of life of patients at all stages of hematological malignancy is greatly affected by the disease and its treatment. There is a wide range of health-related quality of life (HRQoL) issues important to these patients. Any new instrument developed to measure HRQoL of such patients should be content valid, i.e., the items should be comprehensively relevant to the patients and their health condition. The aim of the present study was to examine content validity of a hematological malignancy specific patient reported outcome measure (HM-PRO) developed for use in routine clinical practice.MethodsFollowing literature review and semi-structured interviews, the generated themes and sub-themes were discussed to develop the prototype version of the HM-PRO. A 4-step approach was used for content validation: initial testing and cognitive interviewing; item rating; content validity panel meeting; final field testing and cognitive interviewing. Additional questions related to patients perception
Health, ... Cancer Quality Alliance: Blueprint for a Better Cancer Care System Decision Making in Oncology: A Review of Patient Decision Aids to S...Although cancer management is becoming more structured with disease sp...,News,from,CA:,Cancer,Quality,Alliance,,blueprint,for,a,better,cancer,care,system,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
The Overseas Development Council (then under the leadership of Jim Grant) developed and publicized a measure of (physical) quality of life (the PQLI) many years ago. It combines literarcy rate, infant mortality rate, and life expectancy, using scales from the lowest to the highest values in the global system. It weights the three scales equally. The literacy rate is, in turn, a function of the per capita spending levels on education, estimated cross-sectionally. In many respects the PQLI was a predecessor of the human development index (HDI).. ...
Whole-body effects. Chemotherapy drugs go through your bloodstream and can affect your whole body. That can cause symptoms such as fatigue. Feeling tired or having little energy is a common side effect of many types of chemotherapy. Work with your health care team Consider preparing a list of questions about side effects to ask your health care team so that you can get ready for chemotherapy. Here are some questions you can ask: ...
In this study we tested for differences in physical activity (PA), physical self-concept, and health-related quality of life (HRQoL) between the least and most biologically mature adolescent females within their respective chronological and academic year groups. A total of 222 British female adolescents aged 10 to 14 years (X age = 12.7 years; SD = .8) completed a series of instruments assessing PA, physical self-concept, and HRQoL. Percentage of predicted adult stature was used as an index of biological maturation. A series of univariate analyses of covariance (ANCOVA), controlling for chronological age, revealed that the most mature girls within the chronological and academic year groups generally reported lower levels of physical self-concept and, to a lesser extent, PA and HRQoL when compared to the least mature girls. The findings provide partial support toward the contention that maturity-associated variance in health-related outcomes is accentuated at the extreme ends of the biological ...
Each person going through breast cancer treatment experiences different levels and forms of side effects. Learn more about common side effects experienced here.
Your breast cancer treatment may affect healthy tissues or organs, producing unwanted side effects. These may be connected to medicines, regimens, or therapies.
Issuu is a digital publishing platform that makes it simple to publish magazines, catalogs, newspapers, books, and more online. Easily share your publications and get them in front of Issuus millions of monthly readers. Title: Clyde Life Issue 19 July/August 2014, Author: LifeMags, Name: Clyde Life Issue 19 July/August 2014, Length: 40 pages, Page: 1, Published: 2014-07-01
There is more to nutrition during cancer and cancer therapy than getting enough calories and protein. The foods you choose also help you cope with side effects, such as loss of appetite, nausea, vomiting, diarrhea, chewing and swallowing difficulties and taste changes.. As each persons individual medical profile and diagnosis is different, so is his or her reaction to treatment. Side effects may be severe, mild or absent. Be sure to discuss with your cancer care team any and all possible side effects of treatment before the treatment begins.. ...
Measuring quality of life for elders in post-acute and long-term care (PALTC) has always been a challenge. However, it is essential to ensuring individual residents comfort, dignity, and satisfaction and to identify opportunities for new or changing services. A new study, published in the March issue of JAMDA, establishes a set of standardized, self-reported items and scales to help assess quality of life and services for residents in this care setting. The authors also demonstrated that these scales are significantly related to how residents perceive facilities homelike quality.. In "Hearing the Voice of the Resident in Long Term Care Facilities - An Internationally Based Approach to Assessing Quality of Life," the authors used the InterRAI Self-Report Quality of Life Survey for Long Term Care Facilities to assess residents perceptions about the quality of life and services in their facilities. They scored individual items based on the two most positive categories- "sometimes" and "always." ...
Review of the principles of alternative medicine with referral and consultation services. Extensive information from Dr. Kennedys Book, The Thinking Persons Guide to Perfect Health.
Review of the principles of alternative medicine with referral and consultation services. Extensive information from Dr. Kennedys Book, The Thinking Persons Guide to Perfect Health.
Information on what to expect as you begin cancer treatment, covering side effects such fatigue, hair loss, nausea, and bowel changes.
... is an open access, peer-reviewed, online journal offering high quality articles, rapid publication and wide diffusion in the public domain.Health and Quality of Life Outcomes considers original ...