Myint, PK, Luben, RN, Surtees, PG, Wainwright, NWJ, Wareham, NJ and Khaw, KT (2010) Physical health-related quality of life predicts the incidence of Coronary Heart Disease in the European Prospective Investigation into Cancer (EPIC) - Norfolk prospective population based study. International Journal of Epidemiology, 39 (4). pp. 996-1003. ISSN 1464-3685 Full text not available from this repository. (Request a copy ...
Two self-administered quality-of-life measures, the McGill Quality of Life Questionnaire (MQOL) and the Patient Evaluated Problem Scores (PEPS) were compared in patients receiving palliative care. The MQOL is a multidimensional questionnaire consisting of 16 items in five quality-of-life (QOL) domains: physical symptoms, physical well-being, psychological, existential and support domains. The PEPS is an individualized questionnaire asking patients to identify and rate major problems affecting their QOL. Both questionnaires were completed by 36 patients during outpatient clinic visits in three palliative care settings in Wales. Of those patients who stated their questionnaire preference 60% favoured MQOL due to its comprehensiveness, while others (28%) preferred PEPS due to its simplicity. The MQOL showed excellent internal consistency (a = 0.90). The intrapatient analysis of answers from both questionnaires showed that MQOL was better than PEPS in reporting physical symptoms and support domain, ...
TY - JOUR. T1 - The impact of gastrointestinal and genitourinary toxicity on health related quality of life among irradiated prostate cancer patients. AU - Schaake, Wouter. AU - Wiegman, Erwin M.. AU - de Groot, Martijn. AU - van der Laan, Hans Paul. AU - van der Schans, Cees. AU - van den Bergh, Alfons C.M.. AU - Langendijk, Johannes A.. PY - 2013. Y1 - 2013. N2 - PURPOSE: To determine the impact of late radiation-induced toxicity on health-related quality of life (HRQoL) among patients with prostate cancer.PATIENTS AND METHODS: The study sample was composed of 227 patients, treated with external beam radiotherapy. Common Terminology Criteria for Adverse Events version 3.0 were used to grade late genitourinary and gastrointestinal toxicity. The European Organization for Research and Treatment of Cancer Quality of life Questionnaire C30 (EORTC QLQ-C30) was used to assess HRQoL at baseline, and 6, 12 and 24 months after completion of radiotherapy. Statistical analysis was performed using a ...
Both HRQoL and the prevalence of side effects were not statistically significantly different between screening and control groups whereas treatment choices between the two groups were statistically significantly different. The mean scores of sleeping and sexual dimensions of the 15D and the mean 15D scores of the screening population were statistically significantly lower in comparison with reference population. Treatment choices were associated with the prevalence of prostate-specific side effects, the sexual dimension of the 15D and overall HRQoL. Sex-related symptoms were the most common side effects and higher occurrence was observed in surgery patients. The presence of erectile side effects was associated with the sexual dimension of the 15D and overall HRQoL. However, other side effects were not found to be related to the three dimensions (sleeping, elimination and sexual activity) of the 15D or overall HRQoL. After adjusting for a number of factors, patients who experienced the worst ...
The Physical Quality of Life Index (PQLI) is an attempt to measure the quality of life or well-being of a country. The value is the average of three statistics: basic literacy rate, infant mortality, and life expectancy at age one, all equally weighted on a 0 to 100 scale.. It was developed for the Overseas Development Council in the mid-1970s by Morris David Morris, as one of a number of measures created due to dissatisfaction with the use of GNP as an indicator of development. PQLI might be regarded as an improvement but shares the general problems of measuring quality of life in a quantitative way. It has also been criticized because there is considerable overlap between infant mortality and life expectancy.[1]. The UN Human Development Index is a more widely used means of measuring well-being.. Steps to Calculate Physical Quality of Life:. 1) Find percentage of the population that is literate (literacy rate).. 2) Find the infant mortality rate. (out of 1000 births) INDEXED Infant Mortality ...
Post-procedure, patients remained hospitalized and were monitored for 24 to 48 h. Clinical follow-up was recommended at 3 months and annually. Before and after ablation at 3 months and 1, 2, and 3 years, patients received a questionnaire that included QoL assessment, symptom information, and self-reports of arrhythmia recurrences (and interventions) that occurred outside of follow-up visits. All reported outcomes were timed in relation to the patients last ablation at Mayo Clinic.. Health-related QoL was assessed with the Medical Outcomes Study Short Form-36 (SF-36). The SF-36 contains 8 individual scales, scored from 0 (worst health) to 100 (best health). Raw scores were presented as T scores in comparison with a healthy normal population with a mean score set at 50 with an SD of 10. In addition to a total score, physical component summary (PCS) and mental component summary (MCS) scores were assessed on a raw scale of 0 to 100 (14).. After August 2004, the Mayo AF-Specific Symptom Inventory ...
In a longitudinal study reported in the Journal of Clinical Oncology, Husson et al found that health-related quality of life improved between diagnosis and 2 years after diagnosis in adolescent/young adult (AYA) patients with cancer, but it remained impaired compared with population norms.. Study Details. The study involved 176 patients aged 15 to 39 years with various cancers from 5 U.S. institutions who completed the Short Form-36 Health Survey (SF-36) within 4 months after diagnosis and at 12 and 24 months later. The SF-36 summary physical component scale (PCS) and mental component scale (MCS) scores were converted to T scores ranging from 0 to 100, with a higher score indicating better health-related quality of life.. Changes Over Time. At baseline, AYA patients had significantly poorer mean PCS scores (38.7 vs 52.9, P , .001) and MCS scores (42.9 vs 48.9, P , .001) vs population norms (ages 18-40 years). AYA patients had significant improvements in PCS and MCS scores from baseline at 12 ...
The effects of physical activity on prescription (PAP) on health-related quality of life (HRQoL) in overweight adults are unclear. We therefore aimed to explore the effects of the Swedish PAP model on HRQoL in overweight older adults. Participants were recruited from a cohort of men and women born between 1937 and 1938, and living in Stockholm County. Inclusion criteria were; insufficiently physically active, i.e. |30 min of at least moderate intensity physical activity (PA) per day; body mass index |25 kg/m2; and waist circumference ≥102 cm (men) or ≥88 cm (women). Altogether, 101 individuals, aged 67 years, were randomly assigned to two parallel groups: intervention group (n = 47) receiving individualised PAP or control group (n = 54). The 36-item Short Form Health Survey (SF-36) was administered before and after the six months intervention. Main outcomes were the SF-36 physical component summary (PCS) and mental component summary (MCS) scores. Intention to treat analysis was utilised. Regression
Background Our aim was to investigate the existence of a reciprocal relationship between patients assessment of quality of life and their appraisal of health. If present, this relationship will interfere with the interpretation of heart surgerys effect on overall quality of life. Methods Path analysis was used to investigate reciprocal causal relationships between general health perceptions and overall quality of life before and after heart surgery. Longitudinal data from a study of coronary artery bypass surgery were used to model lagged, cross-lagged, and simultaneous paths over four time-points of assessment from before surgery to one year afterwards. The conceptual framework for the analysis was the Wilson and Cleary causal pathway model. General health perceptions were measured with the Short Form 36. Overall quality of life was measured with i) a single question regarding life satisfaction and ii) the multi-item Quality of Life Survey. Results Acceptable model fit was obtained for ...
Background: The EORTC 24971/TAX 323, a phase III study of 358 patients with unresectable locoregionally advanced squamous cell carcinoma of the head and neck, showed an improved progression-free and overall survival (OS) with less toxicity when docetaxel (T) was added to cisplatin and 5-fluorouracil (PF) for induction and given before radiotherapy (RT). The impact of the addition of docetaxel on patients health-related quality of life (HRQOL) and symptoms was investigated. Methods: HRQOL was assessed at baseline, at end of cycle 2, and 4, 6, and 9 months after completion of RT using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire C30 (QLQ-C30) and the EORTC QLQ Head and Neck Cancer-Specific Module (EORTC QLQ-H&N35). The primary HRQOL scale was global HRQOL per protocol. Results: Compliance to HRQOL assessments was 97% at baseline, but dropped to 54% by 6 months. Data were analysed up to 6 months. There was a trend towards improved global HRQOL ...
TY - JOUR. T1 - Impact of chronic gastrointestinal symptoms in diabetes mellitus on health-related quality of life. AU - Talley, Nicholas J.. AU - Young, Lisa. AU - Bytzer, Peter. AU - Hammer, Johann. AU - Leemon, Melanie. AU - Jones, Michael. AU - Horowitz, Michael. PY - 2001. Y1 - 2001. N2 - OBJECTIVES: Morbidity from GI symptoms in diabetes is considered to be high, but no studies have quantified the impact of GI symptoms in diabetes on health-related quality of life. We hypothesized that diabetics reporting increased GI symptoms would experience more impaired quality of life. METHODS: Subjects from the community with diabetes (n = 892) and outpatients with diabetes (n = 209) were recruited for this study. Subjects were divided into type 1 (diabetes diagnosed at age ,30 yr and requiring insulin) and type 2. A validated questionnaire measuring GI symptoms and diabetes status and the Short Form-36 were completed. The results were compared with Australian normal data. GI symptom groups measured ...
Research Team: Montse Ferrer, Jordi Alonso, Olatz Garin, Àngels Pont. The International health-related Quality of life Outcomes Database (IQOD) Group defines as general objective to develop a database of HRQL item responses, clinical and socio-demographic data from multiple sources of HRQL studies conducted throughout Europe; with the purpose of evaluating the psychometric properties of linguistically validated versions of three HRLQ instruments . The selected instruments were: The Womens Health Questionnaire (WHQ), the Psychological General Well-being Index (PGWB), and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Each of these instruments was selected for the IQOD project because of favourable reports of its reliability and validity, its linguistic adaptation into multiple European languages, and its extensive use throughout Europe and the US. However, the metric properties of these different versions have not been cross-culturally evaluated. The MLHFQ contains 2 domains ...
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Combined exposure to several healthy behaviors (HB) is associated with reduced mortality in older adults but its impact on health-related quality of life (HRQL) is uncertain. This is a cohort study of 2,388 individuals aged ≥60 recruited in 2000-2001, whose data were updated in 2003 and 2009. At baseline, participants reported both traditional HB (non-smoking, being very or moderately active, healthy diet) and non-traditional HB (sleeping 7-8 h/d, being seated <8 h/d, and seeing friends every day). HRQL was measured with the SF-36 questionnaire at baseline, in 2003 (short-term) and in 2009 (long-term); a higher score on the SF-36 represents better HRQL. Linear regression models were used to assess the association between HB at baseline and HRQL in 2003 and ...
The older Hispanic population of the U.S. is growing at a tremendous rate. While ethnic-related risk and complications of diabetes are widely-acknowledged for older Hispanics, less is known about how health related quality of life is affected in this population. Cross-sectional study assessing differences in health related quality of life between older Mexican Americans with and without diabetes. Participants (n = 619) from the Hispanic Established Population for the Epidemiological Study of the Elderly were interviewed in their homes. The primary measure was the Medical Outcomes Study Short Form (SF-36). The sample was 59.6% female with a mean age of 78.3 (SD = 5.2) years. 31.2% (n = 193) of the participants were identified with diabetes. Individuals with diabetes had significantly (F = 19.35, p | .001) lower scores on the Physical Composite scale (mean = 37.50, SD = 12.69) of the SF-36 compared to persons without diabetes (mean = 43.04, SD = 12.22). There was no significant difference between persons
Chronic obstructive pulmonary disease (COPD) is a respiratory disorder, which is currently one of the leading causes of chronic morbidity and
International Journal of Hypertension is a peer-reviewed, Open Access journal that provides a forum for clinicians and basic scientists interested in blood pressure regulation and pathophysiology, as well as treatment and prevention of hypertension. The journal publishes original research articles, review articles, and clinical studies on the etiology and risk factors of hypertension, with a special focus on vascular biology, epidemiology, pediatric hypertension, and hypertensive nephropathy.
Do you ever feel like life is kicking you in the butt? Or do you ever feel like life is dragging you down? Though it may be hard preventing negativity from pulling you into a rut when you have a chronic condition, like hepatitis B, being more positive can help lift your spirits. When you do this, you can improve your health-related quality of life!. Though there is no set definition for health-related quality of life, the CDC defines it as an individuals or a groups perceived physical and mental health over time. Health related quality of life explains how a persons physical, emotional, mental and social aspects impact their overall life. Health-related quality of life can impact your overall well-being, which the CDC defines as a positive outcome that is meaningful for people. Basically, improving health-related quality of life and overall well-being can help people feel that things are going well in their lives. Ultimately, this can help decrease stress and improve how well someone ...
BACKGROUND: The SF-36 is a generic health status measure which has gained popularity as a measure of outcome in a wide variety of patient groups and social surveys. However, there is a need for even shorter measures, which reduce respondent burden. The developers of the SF-36 have consequently suggested that a 12-item sub-set of the items may accurately reproduce the two summary component scores which can be derived from the SF-36 [the Physical Component Summary Score (PCS) and Mental Health Component Summary Score (MCS)]. In this paper, we adopt scoring algorithms for the UK SF-36 and SF-12 summary scores to evaluate the picture of change gained in various treatment groups. METHODS: The SF-36 was administered in three treatment groups (ACE inhibitors for congestive heart failure, continuous positive airways therapy for sleep apnoea, and open vs laparoscopic surgery for inguinal hernia). RESULTS: PCS and MCS scores calculated from the SF-36 or a sub-set of 12 items (the SF-12) were virtually identical
Previous studies have shown that treatment-naïve HCV patients treated with RBV and IFN experience a significant PRO impairment.[13,14] In particular, the use of IFN causes substantial side effects, including debilitating ones such as severe depression, which, in turn, affect patients ability to sustain treatment long enough to obtain a cure whether through medical discontinuation or through patients nonadherence. The use of RBV also has been shown to decrease PROs during treatment. However, the PRO data in patients who are retreated after having experienced another course of treatment have not been reported. Therefore, the aim of this study was to evaluate PROs during treatment with and without the use of IFN in patients who participated in a prior study of an IFN-containing or an IFN-free DAA-based regimen and has not achieved SVR ...
TY - JOUR. T1 - Health-related quality of life. T2 - A guide for the health professional. AU - Nanda, Upasana. AU - Andresen, Elena. PY - 1998. Y1 - 1998. N2 - The importance of evaluating health care in terms of patients quality of life has only recently been acknowledged in the context of outcomes research and the measurement of quality of care. As a health professional, trying to choose the appropriate health status or health-related quality of life (HRQOL) measure can be daunting, as one is faced with a bewildering array of choices. The purpose of this article is to describe the process by which professionals might make a choice about measures in outcomes research. The article includes examples and rationale for using generic or disease- specific HRQOL measures. In addition, examples are provided of HRQOL assessment in two adult chronic disease applications: asthma and congestive heart failure.. AB - The importance of evaluating health care in terms of patients quality of life has only ...
The Medical Outcome Study Short Form 36-Item Health Survey (SF-36) is a self-administered questionnaire that measures the impact of disease on overall quality of life and consists of 36 questions in eight domains. The domains include physical (physical functioning, role limitations due to physical health (role-physical), general health perceptions and pain) and mental domains (energy/fatigue (vitality), social functioning, emotional well-being (mental health), and role limitations due to emotional problems (role emotional)). The individual domain scores are calculated and transformed to range from 0 to 100, with higher scores indicating a better level of functioning ...
The InterStim System is the Only Proven, Long-Term Sacral Neuromodulation Solution for Overactive Active Bladder. DUBLIN - July 17, 2017 - Medtronic plc (NYSE: MDT) today announced that the InterStim(TM) system, which provides sacral neuromodulation therapy, offers sustained long-term efficacy and quality of life improvements for overactive bladder (OAB) at five years.1 Results of the InSite study, which were published online in the Journal of Urology,1 found that 82 percent of patients had therapeutic success (defined as a greater than 50 percent improvement in symptoms) at five years and sustained quality of life improvements. Effective long-term bladder control is critical because OAB is a chronic condition that significantly impacts all aspects of a persons quality of life, including confidence, activities and intimacy, said Steven Siegel, M.D., primary investigator and director, Metro Urology Centers for Female Urology and Continence Care, Minneapolis, Minn. Many struggle to find ...
There is a growing interest to use quality of life as one of the dialysis outcome measurement. Based on the Malaysian National Renal Registry data on 15 participating sites, 1569 adult subjects who were alive at December 31, 2012, aged 18 years old and above were screened. Demographic and medical data of 1332 eligible subjects were collected during the administration of the short form of World Health Organization Quality of Life questionnaire (WHOQOL-BREF) in Malay, English, and Chinese language, respectively. The primary objective is to evaluate the quality of life among dialysis patients using WHOQOL-BREF. The secondary objective is to examine significant factors that affect quality of life score. Mean (SD) transformed quality of life scores were 56.2 (15.8), 59.8 (16.8), 58.2 (18.5), 59.5 (14.6), 61.0 (18.5) for (1) physical, (2) psychological, (3) social relations, (4) environment domains, and (5) combined overall quality of life and general health, respectively. Peritoneal dialysis group ...
TY - JOUR. T1 - Physical activity-related differences in body mass index and patient-reported quality of life in socioculturally diverse endometrial cancer survivors. AU - Rossi, Amerigo. AU - Garber, Carol Ewing. AU - Kaur, Gurpreet. AU - Xue, Xiaonan (Nan). AU - Goldberg, Gary L.. AU - Nevadunsky, Nicole S.. PY - 2017/2/16. Y1 - 2017/2/16. N2 - Purpose: The purpose of this study was to describe physical activity-related differences in body composition, quality of life, and behavioral variables among a socioculturally diverse sample of endometrial cancer survivors. Methods: Ambulatory, English-speaking endometrial cancer survivors (6 months to 5 years post-treatment), who were residents of Bronx, NY, were recruited to complete questionnaires about physical activity (PA), quality of life (QoL), and psychosocial characteristics. Body weight and height were obtained from medical records to determine body mass index (BMI). ANOVA and independent sample t tests were used to determine differences ...
TY - JOUR. T1 - Advances in quality of life measurements in oncology patients. AU - Cella, David. AU - Chang, Chih Hung. AU - Lai, Jin Shei. AU - Webster, Kimberly. PY - 2002/1/1. Y1 - 2002/1/1. N2 - Accurate assessment of the quality of life (QOL) of patients can provide important clinical information to physicians, especially in the area of oncology. Changes in QOL are important indicators of the impact of a new cytotoxic therapy, can affect a patients willingness to continue treatment, and may aid in defining response in the absence of quantifiable endpoints such as tumor regression. Because QOL is becoming an increasingly important aspect in the management of patients with malignant disease, it is vital that the instruments used to measure QOL are reliable and accurate. Assessment of QOL involves a multidimensional approach that includes physical, functional, social, and emotional well-being, and the most comprehensive instruments measure at least three of these domains. Instruments to ...
1. Falder S, Browne A, Edgar D, Staples E, Fong J, Rea S, et al. Core outcomes for adult burn survivors: a clinical overview. Burns. 2009;35(5):618-41. doi: 10.1016/j.burns.2008.09.002 19111399. 2. Spronk I, Legemate C, Oen I, van Loey NE, Polinder S, van Baar ME. Health related quality of life in adults after burn injuries: a systematic review. PLoS One. 2018;13(5):e0197507. doi: 10.1371/journal.pone.0197507 29795616. 3. Group WHOQOL. The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Soc Sci Med. 1995;41(10):1403-9. doi: 10.1016/0277-9536(95)00112-k 8560308. 4. Öster C, Willebrand M, Ekselius L. Health-related quality of life 2 years to 7 years after burn injury. J Trauma Inj Infect Crit Care. 2011;71(5):1435-41.. 5. McGlynn EA, Schneider EC, Kerr EA. Reimagining quality measurement. N Engl J Med. 2014;371(23):2150-3. doi: 10.1056/NEJMp1407883 25470693. 6. Ryan CM, Schneider JC, Kazis LE, Lee A, Li NC, Hinson M, et al. ...
BACKGROUND: After deep venous thrombosis (DVT), many patients have impaired quality of life (QOL). We aimed to assess whether pharmacomechanical catheter-directed thrombolysis (PCDT) improves short-term or long-term QOL in patients with proximal DVT and whether QOL is related to extent of DVT. METHODS: The Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTRACT) trial was an assessor-blinded randomized trial that compared PCDT with no PCDT in patients with DVT of the femoral, common femoral, or iliac veins. QOL was assessed at baseline and 1 month, 6 months, 12 months, 18 months, and 24 months using the Venous Insufficiency Epidemiological and Economic Study on Quality of Life/Symptoms (VEINES-QOL/Sym) disease-specific QOL measure and the 36-Item Short Form Health Survey (SF-36) physical component summary (PCS) and mental component summary general QOL measures. Change in QOL scores from baseline to assessment time were compared in the PCDT and no PCDT ...
Phase I trials aim to identify the recommended dose for further development. Health-related quality of life (HRQoL) could be a complement to the usual National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE) scale to detect adverse events and define the doses. The objective of this study is to review the phase I in oncology which used HRQoL as endpoint. A search in PubMed database identified phase I trials in oncology with HRQoL as endpoint, published between January 2012 to May 2016. Hematological and pediatric phase I were excluded. A total of 1333 phase I were identified and 15 trials were identified with HRQoL as endpoint (1.1%). The European Organisation for Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ-C30) was the most frequently used instrument: 5 studies (33.3%). The targeted dimensions of HRQoL and the minimal clinically important difference were prespecified in 1 study (6.7%) and 2 studies (13.3%), respectively. Twelve studies (80%) described the
Establishing predictors of quality of life (QoL) in individuals with inflammatory bowel disease could help to identify those patients who are most likely to experience poor quality of life.. It would then be possible to target therapeutic interventions appropriately.. Dr Welfare and colleagues undertook a study to investigate how disease-specific QoL depends on demographic, disease related, and physiological markers of disease activity, cognitive representations of illness, and perceived general health status.. The researchers collected a total of 111 Inflammatory Bowel Disease Questionnaires (IBDQ), Medical Outcomes Study 36-Item Short-Form Health Surveys (SF-36), and Illness Perception Questionnaires (IPQ).. The research team was able to determine the extent of disease from records, and disease activity by a symptom index.. The researchers used bivariate analyses and multivariate regression models to identify predictors of disease-specific quality of life.. ...
Among a prospective cohort of patients on hemodialysis who underwent protocolized thyroid testing every 6 months, higher TSH levels were associated with impairments across multiple HRQOL domains. Higher baseline and time-dependent TSH tertiles were associated with lower (worse) HRQOL domain scores for energy/fatigue and physical function, respectively. When examined as a continuous variable, higher baseline TSH levels were associated with worse scores for role limitations due to physical health, energy/fatigue, and pain and trended toward an association with worse scores for social functioning and role limitations due to emotional problems. In analyses of time-dependent TSH as a continuous variable, we similarly observed that higher TSH levels were significantly associated with impairments in role limitations due to physical health and trended toward an association with worse physical function and pain.. In the general population, there has been increasing recognition of the effect of thyroid ...
Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial. ...
DENVER, Oct. 18 Results from a University of Pittsburgh study evaluating intensity modulated radiation therapy (IMRT) for head and neck cancer determined the ideal doses for lessening treatment side effects. The findings were presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver. Despite major advances in chemotherapy and radiation for the treatment of head and neck cancers, many patients continue to suffer debilitating side effects that greatly impact their quality of life, said Dwight E. Heron, M.D., study co-author and associate professor of radiation oncology, University of Pittsburgh School of Medicine and director of radiation oncology, University of Pittsburgh Medical Center. While these high-energy beams are targeted to the tumor site as precisely as possible, they often inadvertently injure healthy tissue that surrounds the tumor site, limiting the doses of radiation that can be used to effectively destroy ...
The Life Quality Index (LQI) is a compound social indicator of human welfare that reflects the expected length of life in good health and enhancement of the quality of life through access to income. The Life Quality Index combines two primary social indicators: the expectancy of healthy life at birth, E, and the real gross domestic product per person, G, corrected for purchasing power parity as appropriate. Both are widely available and accurate statistics. The three components of the Life Quality Index, G, E and K reflect three important human concerns: the creation of wealth, the duration of life in good health and the time available to enjoy life. The amount of life available to enjoy wealth acts as a multiplying factor upon the value of that wealth. Conversely, the amount of income one has to enjoy that available lifetime acts as a multiplier on the expected duration of life. Unlike the United Nations Human Development Index (HDI), the LQI is derived rigorously from the economics of human ...
My name is Ruth Slattery. I am a sixty year old wife and mother of five sons all born at home.. I have always believed in a natural, whole foods approach to life. Having a degree in anthropology from the University of Texas at Austin made understanding and accepting the philosophy and science of the Perfect Health Diet by Paul Jaminet PHD and Shou-Ching Jaminet PHD logical and easy. The atmosphere and support at Albert Oaks makes the transition to a well rounded healthy lifestyle as easy as possible. The delicious meals by chef/owner Damon Young, oak covered grounds,chicken coop, orchard and beautiful vegetable gardens remind us of and attach us to the natural food and life experiences. Participants are encouraged to join in on caring for the chickens, gardening and cooking if interested. Personally I enjoy tending the chickens and gardening.. At Albert Oaks one learns the importance of proper light exposure, sleep, exercise and nutrition in acquiring and maintaining good health. ...
There appears to be a paradox in the prostate cancer literature: despite the fact that age and comorbidities are positively correlated, comorbidities are associated with worse physical and emotional quality of life while age is associated with worse physical quality of life but better emotional quality of life. Emotional support and positive reframing coping strategies may help explain part of this paradox in that they may be more frequently used by older prostate cancer patients and associated with better emotional quality of life. In an effort to better understand this paradox, the present questionnaire-based study of pre-treatment prostate cancer patients (n=74) investigated 1) the relations among age, comorbidity level, emotional quality of life, and physical quality of life, 2) age as a potential moderator of the association between comorbidities and emotional quality of life, and 3) an age-specific coping strategy comprised of emotional support and positive reframing as a mediator of the ...
There appears to be a paradox in the prostate cancer literature: despite the fact that age and comorbidities are positively correlated, comorbidities are associated with worse physical and emotional quality of life while age is associated with worse physical quality of life but better emotional quality of life. Emotional support and positive reframing coping strategies may help explain part of this paradox in that they may be more frequently used by older prostate cancer patients and associated with better emotional quality of life. In an effort to better understand this paradox, the present questionnaire-based study of pre-treatment prostate cancer patients (n=74) investigated 1) the relations among age, comorbidity level, emotional quality of life, and physical quality of life, 2) age as a potential moderator of the association between comorbidities and emotional quality of life, and 3) an age-specific coping strategy comprised of emotional support and positive reframing as a mediator of the ...
Background Chemotherapy treatment for metastatic breast cancer (MBC) has shown significant benefits in survival for breast cancer patients. However, chemotherapy is associated with several side effects that have a significant impact on patients quality of life. The objective of this analysis was to quantify the value patients with MBC place on reduced risk of treatment side effects.. Methods: A willingness to pay (WTP) survey was developed to assess metastatic breast cancer patients willingness to pay for a reduction in the risk of breast cancer treatment side effects. The survey assessed patients WTP for a 25%, 50% and 100% reduction in the risk of all side effects. Patients were also asked to select the side effect they would pay the most to avoid. Additionally, the survey collected demographic information such as treatment regimen, age, race/ethnicity, region, employment status, and insurance type.. Results: The survey was completed by 202 metastatic breast cancer patients. Most survey ...
Milwaukee, WI (PRWEB) May 25, 2017 -- A research study led by Drs. David Skaggs, Behrooz Akbarnia and Michael Vitale compared the health-related quality of
You had the right to know about possible breast cancer treatment side effects - such as from Taxotere - BEFORE beginning treatment.
This study is the first to demonstrate the validity of the EQ-5D-5L UI and EQ-VAS in patients with COPD by showing significant correlations with established disease-specific HRQoL questionnaires and an ability to differentiate between groups defined according to disease severity. Furthermore, we demonstrate that the EQ-5D-5L is responsive to change following pulmonary rehabilitation, and that change in EQ-5D-5L correlates significantly with change in disease-specific HRQoL measures. Furthermore, to our knowledge, this is the first study to prospectively and purposely estimate the MID for both the EQ-5D-5L directly calculated UI and EQ-VAS. Using anchors measuring similar construct, we estimated the minimum important improvement in UI and VAS to be approximately 0.05 and 7.0, respectively.. The generic format of the EQ-5D enables comparisons of health change to be made with other conditions. It has been used in national surveys to measure population-level health status, including the Health ...
With increasing numbers of people suffering from a variety of orthopedic ailments, the use of orthopedic implants has become common. The surgeons use these implants for treatment of a wide range of bone related diseases such as fracture, several bone injuries, and joint pains. The surgeons replace the damaged bone and joint to give relief to the patient.. In India, manufacturers make and supply an entire range of orthopedic implants with high global quality standards ascertain. HEMC Ortho is one of the leading orthopedic implants manufacturers known for its quality production of a whole gamut of the implants. The company makes sure that each phase of the manufacturing takes place with global quality standards met. Implants such as rods, screws, pins, plates and host of others including the instruments are made in India and supplied to the domestic and overseas markets.. Types of implants used in orthopedic surgery There are many types of orthopedic implants. In fact, there are many implants used ...
Acpuris Intensive Spot Treatment - Get up-to-date information on Acpuris Intensive Spot Treatment side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Acpuris Intensive Spot Treatment
Health-related QOL was measured by mean changes from baseline in the EORTC-QLQ-C30 global health status/quality of life composite scale and by mean changes from baseline in the remaining EORTC QLQ-C30 questionnaire, Version 3. The EORTC QLQ-C30 is a questionnaire developed to assess the QOL of cancer patients. The questionnaire is a 30-item tool covering multiple items, including 5 functional scales (physical, role, emotional, social, and cognitive); 3 symptom scales (fatigue, nausea and vomiting, and pain); a global health status/QOL scale; and 6 single items (dyspnea, insomnia, appetite loss, constipation, diarrhea, and financial difficulties). Scores for each item range from 0 to 100. A high score for a functional scale represents a high (healthy) level of functioning, and a high score for the global health status represents a high QOL. However, a high score for a symptom scale represents more severe symptoms ...
Background: In order to assess and plan for changing healthcare needs, the lack of available information regarding temporal changes in the health-related quality of life of a population must be addressed. Aim: This paper aims to describe such changes over 5 years in a general population. Design of study: Longitudinal postal questionnaire study. Setting: UK general practice. Method: This was a longitudinal postal questionnaire study in two general practice populations, using the generic instalment EQ-5D to measure health-related quality of life. Individuals were included if they responded to three postal surveys in 1999, 2001, and 2004 and there were three consecutive values of EQ-5Dindex available between 1999 and 2004. Results: A total of 2498 subjects were included in the study. After adjustment for potential confounders (including ageing), health-related quality of life declined significantly over the observation period. The change in EQ-5Dindex was from 0.79 to 0.74 and for EQ-5Dvas 76.8 to ...
Chronic rhinosinusitis (CRS) is a common disorder with a significant impact on health-related quality of life (HRQL). Due to symptoms based diagnosis, disease severity is usually estimated using questionnaires which evaluate subjective scores on severity of symptoms and deterioration of HRQL, like Sino-Nasal Outcome Test-22 Questionnaire (SNOT-22). Objective severity staging is rather based on computerized tomography (CT) scores than on severity of inflammation. There is recent evidence that perceived stress has significant impact on asthma incidence and hospitalization, as well as on allergic rhinitis. As CRS is comorbidity of asthma and allergic rhinitis, we hypothesized that perceived stress may have impact on severity of CRS. The aim of the study is to correlate objective and subjective outcome measures with perceived stress. ...
IN PATIENTS WITH estrogen receptor-positive, HER2-negative advanced or metastatic breast cancer, better quality of life may be prolonged by delaying the progression of the disease, according to an ongoing quality-of-life assessment from the PALOMA-2 study, presented by Nadia Harbeck, MD, PhD, of the Breast Cancer Center at the University of Munich, Germany, and colleagues, at the 2017 European School of Oncology (ESO)/ European Society for Medical Oncology (ESMO) International Consensus Conference for Advanced Breast Cancer (ABC4) in Lisbon, Portugal.1 Analysis of trial data showed that patients whose disease took longer to progress had a significantly greater delay in the deterioration of health-related quality of life compared with patients whose disease progressed earlier, regardless of which treatment they had received. This study is important because it shows for the first time that progression-free survival determination by imaging in a first-line clinical phase III trial indeed also ...
BC-CfE - Short term health-related quality of life improvement during opioid agonist treatment. - BACKGROUND:Opioid dependence is associated with high levels of morbidity, yet sparse data exists
One hundred thirty-eight patients were included in this analysis. The 47 patients in the HP cohort had taken more preoperative opioids (12.0 ± 21.2 vs 3.6 ± 11.1 morphine equivalent doses, p = 0.01). However, there was no statistically significant difference in Pfirrmann classification (p , 0.15), facet grade (p , 0.11), thecal sac cross-sectional area (p = 0.45), or disc herniation grade (p = 0.39) between the HP and non-HP cohorts. The latter cohort had statistically significant higher preoperative PROMIS scores (36.5 ± 7.0 vs 29.9 ± 6.4, p , 0.001), SF-12 mental component summary scores (48.7 ± 11.5 vs 38.9 ± 16.1, p , 0.001), and SF-12 physical component summary scores (PCS; 32.4 ± 8.6 vs 27.5 ± 10.0, p = 0.005), but a lower Oswestry Disability Index (56.4 ± 22.1 vs 35.4 ± 15.5, p , 0.001). There were only two time points after microdiscectomy when the HP cohort had worse HRQOL scores: at the 2-week follow-up for SF-12 PCS scores (32.4 ± 8.6 vs 29.3 ± 7.1, p = 0.03) and the ...
Background Health-related quality of life (HRQoL) is widely used as an outcome measure in the evaluation of treatment interventions in patients with chronic obstructive pulmonary disease (COPD). In order to address challenges associated with existing fixed-length measures (e.g., too long to be used routinely, too short to ensure both content validity and reliability), a COPD-specific item bank (COPD-SIB) was developed. Methods Items were selected based on literature review and interviews with Dutch COPD patients, with a strong focus on both content validity and item comprehension. The psychometric quality of the item bank was evaluated using Mokken Scale Analysis and parametric Item Response Theory, using data of 666 COPD patients. Results The final item bank contains 46 items that form a strong scale, tapping into eight important themes that were identified based on literature review and patient interviews: Coping with disease/symptoms, adaptability; Autonomy; Anxiety about the course/end-state ...
TY - JOUR. T1 - Quality-of-life assessment as an outcomes measure in critical limb ischemia. AU - Alabi, Olamide. AU - Roos, Matthew. AU - Landry, Gregory. AU - Moneta, Gregory. N1 - Publisher Copyright: © 2016 Society for Vascular Surgery. PY - 2017/2/1. Y1 - 2017/2/1. N2 - Critical limb ischemia (CLI) is a diagnosis plagued by significant comorbidity and high mortality rates. Overall survival remains poor in this population regardless of the procedure-related success as demonstrated by freedom from amputation, intervention, and patency. The literature has traditionally focused on physician-centered and lesion-centered outcomes with regards to limb salvage procedures, but there remains a relative paucity of studies of CLI patients describing patient-centered outcomes such as quality of life (QoL), independent living, and ambulation status. Review of the available literature indicates patients do not always experience significant gains in their QoL after limb salvage interventions, despite ...
TY - JOUR. T1 - Maternal perspectives on childrens health-related quality of life during the first year after pediatric hematopoietic stem cell transplant. AU - Parsons, Susan K.. AU - Shih, Mei Chiung. AU - DuHamel, Katherine N.. AU - Ostroff, Jamie. AU - Mayer, Deborah K.. AU - Austin, Jane. AU - Martini, D. Richard. AU - Williams, Sharon E.. AU - Mee, Laura. AU - Sexson, Sandra Griffin Bishop. AU - Kaplan, Sherrie H.. AU - Redd, William H.. AU - Manne, Sharon. PY - 2006/11/1. Y1 - 2006/11/1. N2 - Objective: To assess the longitudinal health-related quality of life (HRQL) of children receiving hematopoietic stem cell transplantation (HSCT). Methods: Mothers (N = 160) of HSCT recipients aged 5-20 at six US transplant centers completed the Child Health Ratings Inventories (CHRIs), the Disease Impairment Inventory (DSII)-HSCT module, and the Short Form (SF)-36 at baseline, 3, 6, and 12 months. Results: HRQL domain scores at baseline varied by recipient age and program site. Longitudinal data ...
BACKGROUND: Fragrance allergy is a lifelong condition that may give rise to permanent or recurrent contact dermatitis and may affect quality of life (QoL). The effect on QoL has not yet been investigated, and no disease-specific QoL instrument for fragrance allergy exists. OBJECTIVE: To develop and validate a disease-specific instrument to investigate QoL among fragrance-allergic subjects. METHOD: A fragrance QoL instrument (FQL index) was developed on the basis of narratives from 68 fragrance-allergic subjects, and consisted of 13 items. It was tested in a postal survey among 1650 participants patch tested at Gentofte University Hospital (2000-2010). The survey included other QoL instruments [Dermatology Life Quality Index (DLQI) and Short Form 36 (SF36) version 2] and questions on eczema severity (response rate of 66%). A retest was conducted after 3-6 months (response rate of 72.5%). RESULTS: The FQL index showed a significant and strong correlation with the DLQI (rS = 0.70), and disease ...
Background: Approximately 20% of men with a diagnosis of prostate cancer present with locally advanced or advanced disease. Few studies consider longer-term impact of disease progression and treatment adverse effects on health-related quality of life (QoL) of these men. Objective: Describe changes in health-related QoL over 5 years for men with newly diagnosed locally advanced or advanced prostate cancer. Interventions/Methods: Eighty-one men with locally advanced or advanced prostate cancer referred to the study by their treating urologist completed a self-administered questionnaire assessing distress, cancer-specific distress, decision regret, satisfaction with life, and global and disease-specific health-related QoL. Questionnaires were administered close to diagnosis (baseline), 2, 6, 12, 24, 36, 48, and 60 months follow-up. Results: Men were of mean age 68.3 (SD, 7.9) years and at mean of 31.9 (SD, 50.5) days postdiagnosis. The most common treatment received was androgen deprivation therapy (95.1%
Some studies support the use of cannabis for these conditions. Still, because marijuana is federally illegal in the United States, research on medical cannabis to manage cancer symptoms and treatment side effects is limited. Patient surveys have provided important insights about how people use medical cannabis. About 42% of people diagnosed with breast cancer who completed our survey said they used medical cannabis products to manage breast cancer symptoms or treatment side effects. The people who used medical cannabis ranged in age, cancer stage, and treatment phase, and most (75%) found it to be very or extremely helpful. But again, its important to talk to your doctor about using cannabis products, especially during cancer treatment, to make sure its a safe option for you. If you find that your doctor is not knowledgeable or experienced with cannabis, you may want to seek advice from an oncologist who participates in your state or countrys medical cannabis program. Its important for ...
World Health Organization Quality of Life (WHOQOL-BREF) assessment for spinal cord injury. Learn more about personal injury cases in San Francisco by reading our San Francisco Personal Injury Attorney blog.
Thank you for visiting Life Improvement Radio After Dark. You may be wondering whats with the new website and name. First, we would like to thank you for your continued years of supporting Life Improvement Radio After Dark (LIRAD). We are pleased to announce that the station featuring Mature Content for Immature Audiences has been rebranded and renamed as Helium Radio After Dark (HRAD).. What is Helium Radio? Helium Radio is the overarching network that balloons over two existing global radio stations. Life Improvement Radio and now Helium Radio After Dark were born from our sister company, Life Improvement Media Group, Inc. Helium Radio has been a long-term project in the works. Now, each radio show has its own channel on this one-of-a-kind network.. Yes, we did it…we are a marketing and branding agency, after all!. Helium Radio After Dark will still entertain around the clock. For unfiltered, adult content, look no further than Helium Radio After Dark on the all-new Helium Radio Network. We ...
The aims of this study were: (1) to compare the discriminative ability of a disease-specific instrument, the St. Georges Respiratory Questionnaire (SGRQ) to generic instruments (i.e., EQ-5D and SF-36); and (2), to evaluate the strength of associations among clinical and health-related quality of life (HRQL) measures in chronic obstructive pulmonary disease (COPD). We analyzed data collected from 120 COPD patients in a Veterans Affairs hospital. Patients self-completed two generic HRQL measures (EQ-5D and SF-36) and the disease-specific SGRQ. The ability of the summary scores of these HRQL measures to discriminate COPD disease severity based on Global Obstructive Lung Disease (GOLD) stage was assessed using relative efficiency ratios (REs). Strength of correlation was used to further evaluate associations between clinical and HRQL measures. Mean total scores for PCS-36, EQ-VAS and SGRQ were significantly lower for the more severe stages of COPD (p | 0.05). Using SGRQ total score as reference, the
MOREIRA, Ana Catarina et al. Nutritional status influences generic and disease-specific quality of life measures in haemodialysis patients. Nutr. Hosp. [online]. 2013, vol.28, n.3, pp.951-957. ISSN 1699-5198. http://dx.doi.org/10.3305/nh.2013.28.3.6454.. Background: Poor nutritional status and worse health-related quality of life (QoL) have been reported in haemodialysis (HD) patients. The utilization of generic and disease specific QoL questionnaires in the same population may provide a better understanding of the significance of nutrition in QoL dimensions. Objective: To assess nutritional status by easy to use parameters and to evaluate the potential relationship with QoL measured by generic and disease specific questionnaires. Methods: Nutritional status was assessed by subjective global assessment adapted to renal patients (SGA), body mass index (BMI), nutritional intake and appetite. QoL was assessed by the generic EuroQoL and disease specific Kidney Disease Quality of Life-Short Form ...
The purpose of this study was to investigate the costs and health status outcomes of intensive care unit (ICU) admission in patients who present after sudden cardiac arrest with in-hospital or out-of-hospital cardiopulmonary resuscitation. Five-year survival, health-related quality of life (Medical Outcome Survey Short Form-36 questionnaire, SF-36), ICU costs, hospital costs and post-hospital health care costs per survivor, costs per life year gained, and costs per quality-adjusted life year gained of patients admitted to a single ICU were assessed. One hundred ten of 354 patients (31%) were alive 5 years after hospital discharge. The mean health status index of 5-year survivors was 0.77 (95% confidence interval 0.70 to 0.85). Women rated their health-related quality of life significantly better than men did (0.87 versus 0.74; P | 0.05). Costs per hospital discharge survivor were 49,952 €. Including the costs of post-hospital discharge health care incurred during their remaining life span, the total
For almost a year and a half, Shou-Ching and I have been trying to boil down everything we know about ancestral health - diet, nutrition, lifestyle, exercise, cooking, health management - and make it available in accessible forms.. One way were sharing our advice, the Perfect Health Seminar in Pittsburgh next Sunday, still has some open spots. Please join us! But the Perfect Health Retreat has been the truly outstanding laboratory for putting all of our ideas together. We control the environment, the schedule, the food, the exercise, and do health coaching before and after the Retreats. Its a good opportunity to try to optimize everything, teach everything, and see the impact on guests health over the months and years that follow.. Ill be blogging soon about early health results from May and our plans for the upcoming October retreats. But before getting into that, I thought it would be fun to share photos from the May Retreat.. ...
Background: The Chronic Liver Disease Questionnaire (CLDQ) is the first available and widely used disease-specific health-related quality of life (HRQOL) measure for chronic liver disease. It has been adapted to different countries but it has not been validated in the Cantonese-speaking Chinese population in Hong Kong (HK) where 8% of the population has chronic hepatitis B infection. Aim: The aim of this study is to translate, validate and test the psychometric properties of the CLDQ for the Chinese population in HK so that we can have a disease-specific HRQOL measures to evaluate the impact of chronic hepatitis B (CHB) infections.and the effectiveness of treatment. Methods: The Chinese (HK) CLDQ was tested on 150 patients in HK. Each patient completed a structured questionnaire on morbidity and socio-demographic, the Chinese (HK) CLDQ and Chinese (HK) SF-36 administered by a trained interviewer. Scaling assumptions were tested by item-domain correlations. Internal reliability was measured by ...
TY - JOUR. T1 - Satisfaction with dietary life affects oral health-related quality of life and subjective well-being in very elderly people. AU - Iinuma, Toshimitsu. AU - Arai, Yasumichi. AU - Takayama, Midori. AU - Takayama, Michiyo. AU - Abe, Yukiko. AU - Osawa, Yusuke. AU - Fukumoto, Motoko. AU - Fukui, Yusuke. AU - Shioda, Yohei. AU - Hirose, Nobuyoshi. AU - Komiyama, Kazuo. AU - Gionhaku, Nobuhito. PY - 2017. Y1 - 2017. N2 - Age-related deterioration in physical and oral health reduces healthy life expectancy and is thus an important problem for very elderly people. We investigated the effects of satisfaction with dietary life (SDL) in everyday life on oral health-related quality of life (OHRQoL) and subjective well-being and examined associations between these factors. We evaluated 426 elders aged 85 years or older. All participants completed a questionnaire that inquired about age, gender, drinking status, body mass index, cognitive function, disability, and comorbidities, among other ...
Aim: To explore the perceived threat of the risk of graft rejection and its relationship to psychological general well-being and self-efficacy 1-5 years after lung transplantation. Design: A nationwide, cross-sectional cohort study as a part of the Self-management after thoracic transplantation study. Methods: A total of 117 lung transplant recipients due for their yearly follow-up one (N = 35), two (N = 28), three (N = 23), four (N = 20) and 5 years (N = 11) after lung transplantation were included. We used three instruments; the Perceived Threat of the Risk of Graft Rejection, the Psychological General Well-being and Self-efficacy in chronic illness. Results: The lung recipients reported an overall low perceived threat of the risk of graft rejection with no gender differences. Intrusive anxiety explained 24.7% of the variance in the PGWB-sum (p ≤ 0.001) and makes a statistically significant (β = −497; p ≤ 0.001) unique contribution to the overall psychological general well-being (95%CI ...
Abstract: Objective: Although research has been conducted on how nurse staffing levels affect outcomes, there has been little investigation into how the health-related productivity of nurses is related to quality of care. Two major causes of worker presenteeism (reduced on-the-job productivity as a result of health problems) are musculoskeletal pain and mental health issues, particularly depression. This study sought to investigate the extent to which musculoskeletal pain or depression (or both) in RNs affects their work productivity and self-reported quality of care and considered the associated costs.Methods: Using a cross-sectional survey design, a random sample of 2,500 hospital-employed RNs licensed in North Carolina were surveyed using a survey instrument sent by postal mail. Specific measures included questions on individual and workplace characteristics, self-reported quality of care, and patient safety; a numeric pain rating scale, a depression tool (the Patient Health Questionnaire), ...
What is the HDQoL© ?. The Huntingtons Disease health-related Quality of Life questionnaire (HDQoL©) is a standardised instrument for measuring health-related quality of life. It is a validated disease-specific measure designed for Huntingtons disease. The HDQoL© can provide a summary score of overall health-related quality of life, as well as scores on several discrete scales.. The HDQoL© is an initiative of the Quality of Life Working Group of the European Huntingtons Disease Network (EHDN). This international project is funded by the EHDN, led by Dr Aileen Ho as Principal Investigator, and based at the University of Reading, U.K.. Who is the HDQoL© for?. The HDQoL© is for people who are living with Huntingtons disease. This includes people who are at risk for Huntingtons, people who have tested positive for the Huntingtons gene but do not have symptoms,and also for people at early through to late stages of disease. The HDQoL© can be used across the full spectrum of Huntingtons ...
OBJECTIVE: To carry out a longitudinal investigation of functional outcome, health-related quality of life (HRQoL) and treatment strategies in JIA patients who started etanercept ,5 years ago. METHODS: We approached patients whose HRQoL changes were described previously in a subanalysis of the Dutch Arthritis and Biologicals in Children register. Recent disease status, co-morbidities and structural damage were retrieved. Disability and HRQoL were assessed by (Childhood) HAQ [(C)HAQ], Child Health Questionnaire, Short Form 36 and Health Utilities Index Mark 3. Changes over time were analysed with linear mixed models. RESULTS: Forty-three patients (81% response) started etanercept a median 8.5 years ago. At the time of this long-term analysis, median age was 22 years (interquartile range: 18-24 years). HRQoL outcome was similar to HRQoL 15-27 months after the initiation of etanercept; 42% had a (C)HAQ of 0.00 and 67% had achieved inactive disease. Patients reported increasing levels of bodily pain ...
BACKGROUND: Head and neck cancer is one of the six most prevalent neoplasms worldwide. Regardless of tumor site, deterioration of basic functions affecting head and neck areas are perceived and affect patients lives. The aim of this study was to evaluate quality of life (Short Form) and oral health related quality of life (OHIP-14) in patients with head and neck cancer. METHODS: This study was conducted on 42 patients being treated for head and neck cancer. Data collected from the survey included demographic (sex, age, and educational level), quality of life (QoL), and Oral Health Related Quality of Life (OHRQoL), which were, respectively, measured by short form-36 and OHIP-14 questionnaire. Cancer measurements were collected from the patients hospital records. ANOVA and t-tests were used to determine the association between QoL scores and the variables. RESULTS: 83.3% of the participants were men and 16.7% were women. Their mean age was 59.39 ± 12.5 years. 33.3% of the participants had oral cancer.
TY - JOUR. T1 - Health-resource use and quality of life in children with bronchiectasis. T2 - A multi-center pilot cohort study. AU - Lovie-Toon, Yolanda G.. AU - Grimwood, Keith. AU - Byrnes, Catherine A.. AU - Goyal, Vikas. AU - Busch, Greta. AU - Masters, I. Brent. AU - Marchant, Julie M.. AU - Buntain, Helen. AU - OGrady, Kerry Ann F.. AU - Chang, Anne B.. PY - 2019/8/13. Y1 - 2019/8/13. N2 - Background: Bronchiectasis in children is an important, but under-researched, chronic pulmonary disorder that has negative impacts on health-related quality of life. Despite this, it does not receive the same attention as other chronic pulmonary conditions in children such as cystic fibrosis. We measured health resource use and health-related quality of life over a 12-month period in children with bronchiectasis. Methods: We undertook a prospective cohort study of 85 children aged , 18-years with high-resolution chest computed-tomography confirmed bronchiectasis undergoing management in three pediatric ...
The aim of the study was to find out the quality of life in patients with laryngeal cancer after the treatment and to compare it with the quality of life of the general population of the same average age. Data collection was conducted through a cross-sectional quantitative survey using the standardized World Health Organization Quality of Life Questionnaire (WHOQOL-BREF), including the population standards for the age groups. Data collection was undertaken in patients treated at the Otorhinolaryngological Department. Data from 42 patients, with an average age of 70 (16 patients with permanent tracheostomy) were evaluated. A t-test was used for the statistical evaluation of the quality of life in patients after the treatment of laryngeal cancer and the general population of the same average age. We found out that patients displayed a higher quality of life in most areas of the WHOQOL-BREF (physical health, psychological health, social relationships, environment, and overall quality of life and ...
Our study objective was to assess health-related quality of life in survivors of acute lung injury (ALI) and to supplement generic and disease-specific questionnaires with findings from a focus group of ALI survivors. Six patients participated in the focus group, which revealed patient concerns with amnesia, depressed mood, avoidance behaviors, and a prolonged recovery period. Using a cross-sectional study design, 24 patients completed a questionnaire 6 to 41 mo after their lung injury. A total of 43% of the patients with ALI met criteria for depression; 43% had self-reported significant functional limitations, although 39% had minimal or no limitations. Significant respiratory and psychologic symptoms were reported in a quarter to a third of patients. There were large decrements in all domains of the SF-36 (a generic health-related quality-of-life instrument) in our sample compared with norms previously established for the general population. In addition, our patients had similar physical ...
Quality of life (QOL) is an important topic in social and medical sciences, it has a multidimensional nature and is influenced by many factors. Aim of the Work: In this study we want to assess the impact of cognitive impairment on the health related quality of life (HR-QOL) of community dwelling non demented elderly. Subject and Method: 115 non demented elderly, 60 years and older recruited from outpatient geriatric clinic at Al Mansoura General Hospital, Dakahlia, Egypt. Each participant underwent, comprehensive geriatric assessment, assessing cognitive function using the mini-mental state examination (MMSE) and montreal cognitive function test, assessing the health related quality of life (HR-QOL) by the RAND-36 health survey. Results: We found that the elderly with impaired cognition by both MMSE and Montreal test were significantly older; the ones with lower education, with more depressive symptoms, had more functional impairment and had lower HR-QOL scores than the elderly with normal cognitive
Objective: To determine the effect of frailty on Health Related Quality of Life (HRQoL) after treatment for Head and Neck Cancer (HNC). Materials and methods: Patients were prospectively included in OncoLifeS, a data-biobank. Before treatment, patients underwent geriatric screening, including the Groningen Frailty Indicator (GFI) and Geriatric 8 (G8). Patients HRQoL was measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC-QLQ-C30) at three, six, twelve and twenty four months after treatment. Linear mixed models were used for statistical analysis. All models were adjusted for baseline HRQoL values, relevant confounders at baseline and yielded estimates (β), 95% confidence intervals and p-values. Results: 288 patients were included. The mean age was 68.4 years and 68.8% were male. During follow-up, 84 patients had tumor recurrence and 66 died. Response to EORTC-QLQ-C30 ranged from 77.3% to 87.8%. Frail patients, defined by ...
Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of life (Short Form-12 (SF-12)). 3005 adults from randomly selected households were interviewed face-to-face in South Australia. mMRC ≥2 community prevalence was 2.9%. Adjusted analyses showed clinically meaningful and statistically significant decrements of physical and mental components of SF-12 (mean SF-12 summary scores in physical (−13.0 (−16.0 to −10.2)) and mental (−10.7 (−13.7 to −7.8)) components compared with people with mMRC=0) as chronic breathlessness severity increased, across five age groupings. ...
Introduction: Lower health-related quality of life (HRQoL) is associated with fatigue, poor mental and poor gastrointestinal health during the first three months after colorectal cancer (CRC) treatment. Research indicates that maintaining usual activities has a positive impact on HRQoL after treatment for CRC. Illness perceptions have been associated with HRQoL in other cancer diseases, and self-efficacy has been associated with HRQoL in gastrointestinal cancer survivors. Our knowledge about illness perceptions and self-efficacy in relation to maintaining everyday activities and HRQoL following CRC treatment is incomplete. Aim: To explore associations between HRQoL, fatigue, mental health, gastrointestinal health, illness perceptions and self-efficacy in relation to maintaining everyday activities, three months after surgical CRC treatment. A further aim was to test the Maintain Function Scale in a CRC population. Method: The study was cross-sectional. Forty-six persons participated. Data were collected
Data on the impact of long term treatment with immunomodulatory drugs (IMiD) on health-related quality of life (HRQoL) is limited. The HOVON-87/NMSG18 study was a randomized, phase 3 study in newly diagnosed transplant ineligible patients with multiple myeloma, comparing melphalan-prednisolone in combination with thalidomide or lenalidomide, followed by maintenance therapy until progression (MPT-T or MPR-R). The EORTC QLQ-C30 and MY20 questionnaires were completed at baseline, after three and nine induction cycles and six and 12 months of maintenance therapy. Linear mixed models and minimal important differences were used for evaluation. 596 patients participated in HRQoL reporting. Patients reported clinically relevant improvement in global quality of life (QoL), future perspective and role and emotional functioning, and less fatigue and pain in both arms. The latter being of large effect size. In general, improvement occurred after 6-12 months of maintenance only and was independent of the ...
BACKGROUND AND PURPOSE: Limited data exist on health-related quality of life (HRQoL) after intracerebral haemorrhage (ICH). We aimed to determine baseline factors associated with HRQoL among participants of the pilot and main phases of the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT 1 and 2). METHODS: The INTERACT studies were randomised controlled trials of early intensive blood pressure (BP) lowering in patients with ICH (,6 hours) and elevated systolic BP (150-220 mm Hg). HRQoL was determined using the European Quality of Life Scale (EQ-5D) at 90 days, completed by patients or proxy responders. Binary logistic regression analyses were performed to identify factors associated with poor overall HRQoL. RESULTS: 2756 patients were included. Demographic, clinical and radiological factors associated with lower EQ-5D utility score were age, randomisation outside of China, antithrombotic use, high baseline National Institutes of Health Stroke Scale (NIHSS) score, ...
TY - JOUR. T1 - Comparative Performance of Diagnosis-based and Prescription-based Comorbidity Scores to Predict Health-related Quality of Life. AU - Mehta, Hemalkumar. AU - Sura, Sneha D.. AU - Sharma, Manvi. AU - Johnson, Michael L.. AU - Riall, Taylor S.. PY - 2016/2/25. Y1 - 2016/2/25. N2 - OBJECTIVES:: To compare the performance of the health-related quality of life-comorbidity index (HRQoL-CI) with the diagnosis-based Charlson, Elixhauser, and combined comorbidity scores and the prescription-based chronic disease score (CDS) in predicting HRQoL in Agency of Healthcare Research and Quality priority conditions (asthma, breast cancer, diabetes, and heart failure). METHODS:: The Medical Expenditure Panel Survey (2005 and 2007-2011) data was used for this retrospective study. Four disease-specific cohorts were developed that included adult patients (age 18 y and above) with the particular disease condition. The outcome HRQoL [physical component score (PCS) and mental component score (MCS)] was ...
We conducted a prospective study over 24 months to compare health-related quality of life in surgically and medically treated patients with intractable temporal lobe epilepsy. Seizure frequency and health-related quality of life were assessed in 81 patients before and 6, 12, and 24 months after trea …
Paediatric injuries can lead to long-term functional impairment and reduced health-related quality of life, and are a growing public health issue in India. To date, however, the burden has been poorly characterized. This study assessed the impact of non-fatal injuries on health-related quality of life in a prospective cohort study of 373 children admitted to three hospitals in Chandigarh and Haryana states in India. The Pediatric Quality of Life Inventory (PedsQL) and Kings Outcome Scale for Childhood Head Injury (KOSCHI) were administered at baseline (pre-injury) and at 1, 2, 4, and 12 months post-injury by telephone interview. Follow-up at all-time points was completed for 277 (77%) of all living participants. Less than one percent reported ongoing disability at 4 months, and no disability was reported at 12 months. PedsQL physical health scores were below healthy child norms (83.4) at 1 month in the cohort for ages 8-12 years and 13-16 years. Although injuries are prevalent, ongoing impact on
This study is a systematic review of the measurement properties of patient-reported measures of QoL developed and/or validated for infants, children, and adolescents with eczema. A systematic literature search will be carried out in MEDLINE via PubMed and EMBASE using a selection of relevant search terms. Eligible studies will be primary empirical studies evaluating, describing, or comparing measurement properties of QoL instruments for infants, children, and adolescents with eczema. Two reviewers will independently perform eligibility assessment and data abstraction. Evidence tables will be used to record study characteristics, instrument characteristics, measurement properties, and interpretability. The adequacy of the measurement properties will be assessed using predefined criteria. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist will be used to evaluate the methodological quality of included studies. A best evidence synthesis will be ...
View Poster. INTRODUCTION. Quality of life (QOL) in cancer patients has gained increasing attention and may provide prognostic value above and beyond traditional demographic and disease parameters. We evaluate the utility of self-reported QOL to predict mortality in patients with renal cell carcinoma (RCC).. METHODS. The Medicare Health Outcomes Survey was linked to the SEER database to identify patients who completed a QOL questionnaire after the diagnosis of RCC from 1998-2014. Mental component summary (MCS) and physical component summary (PCS) scores were classified as high (≥50) or low (. RESULTS. A total of 1494 patients with a median age of 73.4 years (IQR 68.8-79.3) at survey completion were included. Median follow-up was 5.6 years (IQR 4.0-8.3). There were 747 deaths, of which 139 were due to RCC. Cox regression showed that each additional MCS and PCS point reduced the hazard of ACM by 1.3% (95% CI 0.981-0.993, PPP=0.02), 4.55 (95% CI 1.57-13.18, P=0.005), and 3.11 (95% CI 1.35-7.16, ...
BISAC: PSY036000. The state of health and life satisfaction are influenced not only by social and demographic factors, but also by a number of other factors: the rate of occurrence of sickness and health problems, lifestyle, how leisure time is spent, a balanced diet, ecological conditions, etc. This book provides a review of determinants of life satisfaction, psychological implications, and the impact of life satisfaction on the quality-of-life. Chapter One studies the influence of social and demographic factors (age, gender group, lifestyle, presence or absence of chronic diseases) on parameters of self-assessed health and life satisfaction by studying the population of Poland. Chapter Two provides an evidence-based review of gratitude interventions. Chapter Three investigates the connection between well-being and time use with the focus on working parents. Chapter Four examines the impact of health-related quality of life on female migrant workers suffering from cadmium poisoning in China ...
BETHESDA, Md-The National Cancer Institute has released a summary of published data derived so far from the Prostate Cancer Outcomes Study (PCOS), which seeks to determine the effect of various therapies for primary invasive prostate cancer on patients quality of life.
J Clin Endocrinol Metab. 1995 Dec;80(12):3585-90.. Burman P, Broman JE, Hetta J, Wiklund I, Erfurth EM, Hagg E, Karlsson FA.. Department of Medicine, University Hospital, Uppsala, Sweden.. We examined the effect of GH supplementation on the psychological capacity and sense of well-being in 36 patients with adult-onset GH deficiency (GHD). Recombinant human GH was given in a 21-month cross-over, double blind trial, and quality of life was assessed by using three self-rating questionnaires: the Hopkins Symptom Check List (HSCL), the Nottingham Health Profile (NHP), and the Psychological General Well-Being index. In addition, at the final examination the spouses completed a short questionnaire concerning their partner. Before treatment, the patients had lowered quality of life as determined by the HSCL and NHP inventories, and a correlation between the duration of GHD and the reported symptoms was observed. Upon treatment, the HSCL score was lower (better) after placebo administration (mean +/- SD, ...
This randomized clinical trial examined if a primary care-based intervention improves mental health-related quality of life among survivors of sepsis. Two hundred ninety-one patients 18 yr or older who survived sepsis, including septic shock, were recruited from nine intensive care units (ICUs) across Germany. Participants were randomized to usual care (n = 143) or to a 12-month intervention (n = 148). Usual care was provided by their primary care physician (PCP) and included periodic contacts, referrals to specialists, and prescription of medication, other treatment, or both. The intervention included PCP and patient training, case management provided by trained nurses, and clinical decision support for PCPs by consulting physicians. The primary outcome was change in mental health-related quality of life between ICU discharge and 6 months after ICU discharge using the Mental Component Summary of the 36-Item Short-Form Health Survey. It was found that among survivors of sepsis and septic shock, ...
Whereas adult survivors of childhood cancer from the CCSS report more symptoms of psychological distress compared with siblings, both groups report better psychological adjustment than that of population norms. Survivors report poorer HRQOL in physical and social but not in mental health domains compared with siblings. Compared with U.S. population norms, survivors have increased risk of poor HRQOL in physical and social domains, with the largest effect size in vitality. Compared with population norms, siblings fare better in physical function and general health, and both survivors and siblings report better mental health than does the general population, as well as high levels of current life satisfaction. Except for CNS tumor survivors, both groups also expect high life satisfaction in 5 years. Our findings add to information from previous CCSS estimates of health status (24) and chronic disease (27). Despite their increased risk for poor health status, and the fact that ,70% of childhood ...
Objectives: To evaluate the effect of infliximab on health related quality of life (HRQoL) and physical function in patients with active psoriatic arthritis (PsA) in the IMPACT 2 trial.. Methods: 200 patients with PsA unresponsive to conventional treatment were randomised to intravenous infusions of infliximab 5 mg/kg or placebo at weeks 0, 2, 6, 14, and 22; patients with inadequate response entered early escape at week 16. HRQoL was assessed using the Short Form-36 (SF-36) at weeks 0, 14, and 24. Functional disability was assessed using the Health Assessment Questionnaire (HAQ) at every visit through week 24. Associations between changes in quality of life (SF-36) and articular (American College of Rheumatology (ACR)) and dermatological (Psoriasis Area and Severity Index (PASI)) responses were examined.. Results: Mean percentage improvement from baseline in HAQ was 48.6% in the infliximab group compared with worsening of 18.4% in the placebo group at week 14 (p,0.001). Furthermore, 58.6% and ...
Author(s): Ibrahim, John M; Singh, Paramjit; Beckerman, Daniel; Hu, Serena S; Tay, Bobby; Deviren, Vedat; Burch, Shane; Berven, Sigurd H | Abstract: Study Design:Retrospective case series. Objectives:Both the rate and complexity of spine surgeries in elderly patients has increased. This study reports the outcomes of multilevel spine fusion in elderly patients and provides evidence on the appropriateness of complex surgery in elderly patients. Methods:We identified 101 patients older than70 years who had ≥5 levels of fusion. Demographic, medical, and surgical data, and change between preoperative and >500 days postoperative health survey scores were collected. Health surveys were visual analogue scale (VAS), EuroQoL 5 Dimensions (EQ-5D), Oswestry Disability Index (ODI), Scoliosis Research Society questionnaire (SRS-30), and Short Form health survey (SF-12) (physical composite score [PCS] and mental composite score [MCS]). Minimal clinically important differences (MCIDs) were defined for each survey.
TY - JOUR. T1 - The impact of implantable cardioverter-defibrillator implantation on health-related quality of life in the DANISH trial. AU - Bundgaard, Johan S. AU - Thune, Jens J. AU - Nielsen, Jens C. AU - Videbæk, Regitze. AU - Haarbo, Jens. AU - Bruun, Niels E. AU - Videbæk, Lars. AU - Aagaard, David. AU - Korup, Eva. AU - Jensen, Gunnar. AU - Hildebrandt, Per. AU - Steffensen, Flemming H. AU - Eiskjær, Hans. AU - Brandes, Axel. AU - Thøgersen, Anna M. AU - Melchior, Thomas M. AU - Pedersen, Ole D. AU - Gustafsson, Finn. AU - Egstrup, Kenneth. AU - Hassager, Christian. AU - Svendsen, Jesper H. AU - Høfsten, Dan E. AU - Torp-Pedersen, Christian. AU - Pedersen, Susanne S. AU - Pehrson, Steen. AU - Køber, Lars. AU - Mogensen, Ulrik M. N1 - Published on behalf of the European Society of Cardiology. All rights reserved. � The Author(s) 2019. For permissions, please email: [email protected] PY - 2019/6/1. Y1 - 2019/6/1. N2 - AIM: The Danish Study to Assess the Efficacy of ...