One herb in particular, Psoralea corylifolia (Chinese name: bu gu zhi), is very effective in vitiligo treatment. A member of the pea family, psoralea is also commonly used in Indian Ayurvedic medicine. In Chinese medicine, besides treating vitiligo, it is widely used for the healing of bone fractures. In fact, the Chinese name bu gu zhi translates as "tonify bone resin." It is also used for low back and knee pain, as well as impotence, bed wetting and hair loss. It also has other benefits such as fighting cancer, dilating the coronary arteries, fighting the bacteria that cause tuberculosis, and treating psoriasis. The list of benefits of this great herb is long. The way this herb works to treat vitiligo is that it increases the photosensitivity of the skin, making it more sensitive to ultraviolet radiation, and therefore more prone to re-pigmentation. Although there has been some concern about the safety of long-term use of psoralea, Merry Clinic herbal products that contain psoralea are very ...
Looking for Psoralea esculenta? Find out information about Psoralea esculenta. or perennial plant of the family Leguminosae , indigenous to the American prairies and valued by Native Americans for the starchy tuberous root that was... Explanation of Psoralea esculenta
Uses, Benefits, Cures, Side Effects, Nutrients in Psoralea Oil. List of various diseases cured by Psoralea Oil. How Psoralea Oil is effective for various diseases is listed in repertory format. Names of Psoralea Oil in various languages of the world are also given.
Two new species of Psoralea L. are described: Psoralea diturnerae A. Bello, C.H. Stirt. & Muasya, sp. nov. and P. vanberkelae C.H. Stirt., A. Bello & Muasya, sp. nov. Psoralea diturnerae is endemic to the Outeniqua mountains (Camferskloof ) and is characterised by a mass of numerous basal shoots out of which emerge 2-3 woody stems up to 2 m tall, 3-foliolate needle-like leaflets at the base of the seasonally growing shoot reducing to one towards the apex and bearing numerous 1-3-flowered axillary inflorescences along its length; each mauve to purple and white flower subtended by a trifid cupulum. Psoralea vanberkelae is characterised by its spreading mounding habit, short tightly packed fleshy leaves, with large impressed papillae, densely glandular short broadly triangular stipules, pale to intense mauve to deep blue flowers, standard with a dark purple central blotch above a M-shaped white patch situated above claw, and khaki seeds with purple flecks ...
Kannada : Bavanchi, Tamil : Karpokarishi, Malayalam : Karboga-Ari, Telugu : Bhavanchi-Vittulu, Hindi : Bavanchiyani-Baschi / Bakuchee, Bengali : Bavachi, Konkani : Vakuchu and Marathi : Bavanchi. Psoralea corylifolia (Babchi) is an important plant in the Indian Ayurveda and Tamil Siddha systems of medicine, and also Chinese medicine. The seeds of this plant contain a variety of coumarins including psoralen. The seeds have a variety of traditional medicinal uses, but the specific role (if any) of psoralen in these uses is unknown. An extract of the plants fruit Fructus psoraleæ has been shown to act as a norepinephrine-dopamine reuptake inhibitor in vitro. Extracts obtained from the seeds of P. corylifolia have been shown to inhibit mitochondrial complex I in vitro and may therefore increase susceptibility to oxidative stress. P. corylifolia has been implicated in at least one case of severe hepatotoxicity in a 64-year-old woman who self-medicated with a variety of Aryuvedic herbs for her ...
Psoralea corylifolia is a ANNUAL growing to 0.6 m (2ft). It is in flower from Jul to August, and the seeds ripen from Sep to October. The flowers are hermaphrodite (have both male and female organs) and are pollinated by Insects.It can fix Nitrogen. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils and prefers well-drained soil. Suitable pH: acid, neutral and basic (alkaline) soils. It cannot grow in the shade. It prefers moist soil.
Vashisht Psoralea Cory Gel, Homeopathy for Skin diseases like leucoderma (vitiligo), psoriasis, eczema, leprosy etc. Psoralea corylifolia, commonly known as babchi (Kushtanashini), is a popular herb, which has since long been used in traditional Ayurvedic and Chinese medicine for its top effects to cure various skin diseases.
Evidence-Based Complementary and Alternative Medicine (eCAM) is an international peer-reviewed, Open Access journal that seeks to understand the sources and to encourage rigorous research in this new, yet ancient world of complementary and alternative medicine.
Bello, A. et al. 2015: Psoralea diturnerae and P. vanberkelae (Psoraleeae, Fabaceae): two new species restricted to the Core Cape Region of South Africa. PhytoKeys, 44: 97-107. doi: 10.3897/phytokeys.44.8999 reference page ...
Get the curative action of Psoralea in leucoderma (external), Skin pigmentation regulator, treats skin discoloration as in vitiligo
Psoralidin (PSO), a natural furanocoumarin, is isolated from Psoralea corylifolia L. possessing anti-cancer properties. However, the mechanisms of its effects remain unclear. Herein, we investigated its anti-proliferative effect and potential approaches of action on human lung cancer A549 cells. Cell proliferation and death were measured by MTT and LDH assay respectively. Apoptosis was detected with Hoechst 33342 staining by fluorescence microscopy, Annexin V-FITC by flow cytometry and Western blot analysis for apoptosis-related proteins. The autophagy was evaluated using MDC staining, immunofluorescence assay and Western blot analyses for LC3-I and LC3-II. In addition, the reactive oxygen species (ROS) generation was measured by DCFH2-DA with flow cytometry. PSO dramatically decreased the cell viabilities in dose- and time-dependent manner. However, no significant change was observed between the control group and the PSO-treated groups in Hoechst 33342 and Annexin V-FITC staining. The expression of
Fructus Psoraleae is the seed of Psoralea corylifolia Linn. It is the main ingredient of the herbal mixtures such as Qubaibabuqi, popular in China, India and
Alzheimers disease (AD) is a serious threat for the aging society. In this study, we examined the preventive effect of the total prenylflavonoids (TPFB) prepared from the dried fruits of Psoralea corylifolia L., using an age-related AD mouse model SAMP8. We found that long-term dietary TPFB at 50 mg/kg·day significantly improved cognitive performance of the SAMP8 mice in Morris water maze tests, similar to 150 mg/kg·day of resveratrol, a popular neuro-protective compound. Furthermore, TPFB treatment showed significant improvements in various AD markers in SAMP8 brains, which were restored to near control levels of the normal mice, SAMR1 ...
Dietary Supplement:Experiment group:. Fructus Cnidii,Psoralea Corylifolin L.3monkshood. -Granules,Oral(add into the breast cancer postoperative prescription solution),A Pack(Fructus Cnidii 9g3Psoralea Corylifolin L. 15g3monkshood 9g),Bid Days,3 Periods(a month is a period),Until progression/unacceptable toxicity. Breast Cancer Postoperative Prescription. -Water Decoction,Oral,200ml,Bid Days,3 Periods(a month is a period),Until progression/unacceptable toxicity. Dietary Supplement:Contrast Group:. Breast Cancer Postoperative Prescription. -Water Decoction,Oral,200ml,Bid Days,3 Periods( a month is a period),Until progression/unacceptable toxicity ...
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If you didnt read Chinese, you might not know, at first glance, that this box holds a product whose translated name is "Tightens Vagina Expert.". You might also not realize that the ingredients list is as follows: top soybean extract, collagen, albizia julibrissin durazz, galla chinensis, psoralea corylifolia, incaryillea sinemsis lam, morinda umbellate, cortext eucommiae, pericarpium granati, rhizome curcumae longae, and so on.. It actually says "and so on" at the end of the ingredients. I think they got to a certain point and just said "Fuck it, its full of a bunch of weird shit, you dont know what it is and you dont care if youre eating a mystery pill to tighten vagina expert.". ...
Bakuchiol is a chemical entity that can be naturally found in Psoralea corylifolia, and it has many amazing benefits to the skin that is excellent for spa treatments.
In the study to observe the clinical effect of traditional Chinese medicine Bushen Houxue (BSHX) (dodder seed 20 g, prepared rehmannia root 10 g, mulberry mistletoe 20 g, epimedium 15 g, psoralea fruit 10 g, solomonseal rhizome 10 g, honeylocust thorn 15 g, peach kernel 10 g, pleione bulbocodioides 10 g, red sage root 20 g, and licorice root 6 g,) method combined with ultrasound-guided follicle aspiration (MFA) in treating refractory polycystic ovary syndrome (PCOS), showed ...
On external application, it acts as styptic.. Effect on Tridosha - Balances Vata and Kapha.. Dosage:. 250 mg once or twice a day before or after food or as directed by Ayurvedic doctor.. It is traditionally administered along with Psoralea seeds, Triphala decoction and Honey.. Kaseesa Bhasma ingredients, how to make? :. Shuddha Kasis - Purified Green Vitriol - 100 g.. Purified Green Vitriol is triturated with Kanji (fermented gruel), thin cakes are prepared and heated in a closed container under 300 - 500 degree celcius to obtain Red coloured Kaseesa Bhasma.. Reference: Rasa Tarangini.. ...
1a small full depth botch:Aproaerema anthyllidella. 1b corridor, widening into a small full depth botch; perhaps only occasionally a miner: Cnephasia longana. 1c gallen etc =, Tabellen voor alle parasieten per soort ...
Treatment options of Vitiligo:. 1. Steroid Intake:. Most skin experts recommend increasing the intake of Vitamin D and steroids to recover Vitiligo correctly. The steroid supports in re-pigment discolored parts, and the Vitamin D supports replace dead skin cells.. 2. Topical Corticosteroid Creams:. Vitiligo patients can use these skin creams on your their skin to initiate re-pigmentation cells of the skin.. 3. Oral PUVA Therapy:. Oral PUVA therapies can assistance to recover severe Vitiligo issues in People.. Natural Treatment Choices for Vitiligo:. Psoralea seeds, Radish Seeds, Basil leaves and lime juice, Red clay, Copper treated water, Turmeric, Babchi seeds are some Herbal options for Vitiligo Natural Treatment. These herbal seeds work in vitiligo treatment naturally without any side effects.. ...
Aconite, like cinnamon bark, helps restore warmth to the kidney; epimedium, psoralea, and cuscuta further enhance the kidney yang and produce warmth. Citrus is included here primarily to aid the digestion of the rich tonic herbs, mainly the rehmannia. These amounts are for a one day dosage; the herbs are decocted, dried, and made into tablets; the usual instruction is to take 5 tablets each time, three times daily. To treat polycystic ovaries (or bronchitis in which there is substantial phlegm accumulation), this formulation might be combined with a phlegm-resolving formula such as Tan Yin Wan (pill for phlegm accumulation). Tan Yin Wan contains the many of the same ingredients as Cinnamon and Rehmannia Combination, except that ma-huang and deer antler gelatin are replaced by atractylodes (cangzhu and baizhu), aconite, raphanus (laifuzi), and perilla fruit (zisuzi). This pill treats the combined syndrome of deficiency of spleen and kidney yang(1833 ...
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Description: Bladder Strength Formula Guaranteed Potency Butterbur Directions: As a dietary supplement, take two capsules as needed (up to four daily). Serving Size: 2 Capsule 30 Servings per container Ingredients: Amount per serving: % Daily Value: Alpinia Oxyphylla Extract 5:1 [fruit/seed], Lobelia [aerial] Total Carbohydrate less than 1 g less than 1% Dietary Fiber less than 1 g 3% Flowtrol Proprietary Blend (Cranberry [Vaccinium macrocarpon] [berry extract] [as CranActin Cranberry AF Extract], Morinda Root Extract 5:1 [root], Psoralea Fruit Extract 5:1 [fruit], Raspberrry Fruit Extract 5:1 [Rubus Chingii] [fruit] 870 mg Guaranteed Potency Butterbur (petasites hybridus) (root extract) (Guaranteed to contain 15mg [15%] sesquiterpenes) 100 mg Other Ingredients: Gelatin Capsule, Cellulose, Maltodextrin, Magnesium Stearate, Silica and Magnesium Hydroxide
... Dietary Supplement. For Professional Use Only. Formulated by Jane Lyttleton. Only the finest hand-selected Chinese herbs are used. Rigorous manufacturing astandards are applied at each stage of production.. Recommended Adult Dosage: 2-3 tablets, 3 times daily.. Ingredients: Rehmannia root (prepared), Chinese yam rhizome, Asiatic cornelian cherry, Dong quai root, White peony root, Chinese salvia root and rhizome, Tree peony root bark, Poria, Chinese dodder seed, Silk tree bark, Asian water plantain rhizome, Chinese amomum fruit, Psoralea fruit, Cyperus rhizome (prepared), Deer horn gelatin (soybean), Fluorite, Epimedium herb.. 50mg excipients and binders: silicon dioxide (glidant/dehydrant), stearic acid (lubricant/binder), microcellulose (coating). Use only under the direct supervision of a qualified health care practitioner, seek their advice if pregnant or nursing. Keep out of reach of children. Keep tightly capped and out of direct sunlight. Store at room ...
... Dietary Supplement. For Professional Use Only. Formulated by Jane Lyttleton. Only the finest hand-selected Chinese herbs are used. Rigorous manufacturing astandards are applied at each stage of production.. Recommended Adult Dosage: 2-3 tablets, 3 times daily.. Ingredients: Chinese dodder seed, Dong quai root, Astragalus root (honey fried), Cistanche salsa herb, Spathlobus root and vine, Silk tree bark, Cyperus rhizome (prepared), Chinese red peony root, White peony root, Chinese yam rhizome, Rehmannia root (prepared), Ligustrum fruit, Tree peony root bark, Poria, Psoralea fruit, Carthamus flower, Fluorite, Gleditsia spine. 50mg excipients and binders: silicon dioxide (glidant/dehydrant), stearic acid (lubricant/binder), microcellulose (coating). Use only under the direct supervision of a qualified health care practitioner, seek their advice if pregnant or nursing. Keep out of reach of children. Keep tightly capped and out of direct sunlight. Store at room ...
Kat - As we just heard from Elaine, DNA sequencing technology is enabling us to uncover the genetic faults driving an individual persons cancer, and target them with specific drugs. Many of these drugs are showing impressive effects in clinical trials, and some have been licensed for use for patients on a wider scale. But all too often - after months or even years - the cancer comes back, because the cancer cells have evolved resistance to the therapy.
Subgenera of genus Betula (Birch), are; Bark on twigs rich in methyl salicylate (oil of wintergreen). Female catkins erect. Diploid (2n = 28). Betula lenta - Sweet Birch or Cherry Birch Betula lenta subsp. uber - Cherry Creek Birch Hexaploid (6n = 84). Betula allegheniensis - Yellow Birch (B. lutea) Decaploid (10n = 140). Betula austrosinensis - South China Birch Betula globispica - Betula insignis - Betula medwediewii - Caucasian Birch Duodecaploid (12n = 168). Betula megrelica - chromosome number not reported Betula corylifolia - Hazel-leaf Birch Betula grossa - Japanese Cherry Birch Betula insignis - Bark on twigs contains some methyl salicylate. Female catkins pendulous. Betula alnoides - Alder-leaf Birch Betula alnoides subsp. luminifera - Betula maximowiczii - Monarch Birch Bark on twigs without methyl salicylate. Female catkins erect. Diploid (2n = 28). Betula calcicola - Betula chichibuenis - Betula costata - Korean birch Betula nigra - River Birch or Black Birch Betula potaninii - ...
TY - JOUR. T1 - A novel class of pyranocoumarin anti-androgen receptor signaling compounds. AU - Guo, Junming. AU - Jiang, Cheng. AU - Wang, Zhe. AU - Lee, Hyo Jeong. AU - Hu, Hongbo. AU - Malewicz, Barbara. AU - Lee, Hyo Jung. AU - Lee, Jae Ho. AU - Baek, Nam In. AU - Jeong, Jin Hyun. AU - Kim, Dae Keun. AU - Kang, Kyung Sun. AU - Kim, Sung Hoon. AU - Lu, Junxuan. PY - 2007/3/1. Y1 - 2007/3/1. N2 - Androgen and the androgen receptor (AR)-mediated signaling are crucial for prostate cancer development. Novel agents that can inhibit AR signaling in ligand-dependent and ligand-independent manners are desirable for the chemoprevention of prostate carcinogenesis and for the treatment of advanced prostate cancer. We have shown recently that the pyranocoumarin compound decursin from the herb Angelica gigas possesses potent anti-AR activities distinct from the anti-androgen bicalutamide. Here, we compared the anti-AR activities and the cell cycle arrest and apoptotic effects of decursin and two natural ...
DALLAS Dec. 16, 2009 Aided by next-generation DNA sequencing technology, an international team of researchers has gained insights into how more than 60 carcinogens associated with
NABsys, a Providence, RI-based startup focused on advanced DNA sequencing technology, has raised $4 million in a Series A round of financing intended to he
Panelists give an overview of the power of DNA sequencing technology, and discuss the opportunities and issues raised by the application of DNA sequencing and companion technologies to different fields. Part of Cornells sesquicentennial celebration, April 24-17, 2015
The cyclic trithiocarbonates 1,3-dithioIane-2-thione (4) and 1,3-dithiole-2-thione (9) in 1,2-dichloroethane and MeCN, respectively, react with alkyl- and phenyl-substituted oxiranes 2 in the presence of Lewis acids to give 1-oxa-4,6,9-trithiaspiro[4.4]nonanes 5 and 6 (Scheme 2) and 1-oxa-4,6,9-trithiaspiro[4.4]non-7-enes 10 and 11 (Scheme 3), respectively. The reactions proceed regioselectively yielding 2-alky1 (5,10) and 3-phenyl derivatives (6, 11) as the main products. From the reaction of 4 and 2-phenyloxirane (2e) with TiCl4, 2-phenyl-1,4,6,9-tetrathiaspiro[4.4]nonane (7) is isolated as a minor product. The molecular structures of 5a, 6e, and 7 are established by X-ray crystallography. ...
Reagents: 5 mol equiv. of tri-n-butylvinylstannane, 0.040 mol equiv. Pd(OAc)2 , XPhos, 0.080 mol equiv., 60°C overnight, 64% yield.. Kügelrohr distillation then delivers the pure TVE. In a nice "green touch" distillation of the tri-n-butyltin chloride into vinyl magnesium bromide regenerates the coupling starting material. TVE is stable in light and air for an extended period of time. The group also made a range of TVE analogues containing useful functionality and producing a nice x-ray of the tetra phenyl derivative:. ...
Demonstrating the potential of precision medicine, an international study based at UT Southwestern Medical Center used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility ...
Abstract from a paper by Ujvarosi et al. (2019), published in Chemospere : Microginins (MGs) are bioactive metabolites mainly produced by Microcystis spp., (Cyanobacteria) commonly found in eutrophic environments. In this study, the cytotoxic and genotoxic activities of four MG congeners (MG FR3, MG GH787, cyanostatin B, MGL 402) and a well characterized cyanobacterial extract…
DNA sequencing technology, a key tool in characterizing microbes in the environment, just keeps getting cheaper and easier. Right now there are some really nice technologies out there in machines from Illumina/Solexa, Roche/454 and ABI. And coming on the horizon are some new systems that possibly will be either "better" in some way or allow …. ...
80592-86-5 - ZLZINPAIXXXARB-UHFFFAOYSA-N - Benzofuran, 5-bromo-2-(diethylaminomethyl)-3-phenyl- - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Define benzofuran. benzofuran synonyms, benzofuran pronunciation, benzofuran translation, English dictionary definition of benzofuran. n. A colorless liquid, C8H6O, found in coal tar and used to make thermoplastic resins for paints and varnishes. Also called coumarone . n a colourless...
The University of Alabama at Birmingham today announced that Illumina Inc. has licensed the rights to a DNA sequencing technology...
Publication Bioinformatics. Bioinformatics is a relatively new field of research. It evolved from the requirement to process, characterize, and apply the information being produced by DNA sequencing technology. The production of DNA sequence data con...
In melanoma, vascular endothelial growth factor-C (VEGF-C) expression and consequent lymphangiogenesis correlate with metastasis and poor prognosis. VEGF-C also promotes tumor immunosuppression, suggesting that lymphangiogenesis inhibitors may be clinically useful in combination with immunotherapy. We addressed this concept in mouse melanoma models with VEGF receptor-3 (VEGFR-3)-blocking antibodies and unexpectedly found that VEGF-C signaling enhanced rather than suppressed the response to immunotherapy. We further found that this effect was mediated by VEGF-C-induced CCL21 and tumor infiltration of naïve T cells before immunotherapy because CCR7 blockade reversed the potentiating effects of VEGF-C. In human metastatic melanoma, gene expression of VEGF-C strongly correlated with CCL21 and T cell inflammation, and serum VEGF-C concentrations associated with both T cell activation and expansion after peptide vaccination and clinical response to checkpoint blockade. We propose that VEGF-C ...
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the inclusion complex of aegelinol in β-cyclodextrin was determined (a = 15.404(1) Å, b = 15.281(1) Å, c = 17.890(1) Å, α = 99.662(1), β = 113.4230(1), γ = 102.481(1)°, P1; R1 = 6.71%) and allowed unambiguous determination of the absolute configuration of the stereogenic center of aegelinol. The pyranocoumarin guest is included within the cylindrical cavity formed by dimeric β-cyclodextrin molecules with a head-to-head arrangement. Crystal structure of aegelinol alone was also determined (a = 6.8921(3) Å, b = 11.4302(9) Å, c = 44.964(3) Å, P212121; R1 = 4.44%) and allowed precise determination of its geometry. Aegelinol crystallizes with three molecules in the asymmetric unit held together by H-bonds and π-stacking interactions.
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the inclusion complex of aegelinol in β-cyclodextrin was determined (a = 15.404(1) Å, b = 15.281(1) Å, c = 17.890(1) Å, α = 99.662(1), β = 113.4230(1), γ = 102.481(1)°, P1; R1 = 6.71%) and allowed unambiguous determination of the absolute configuration of the stereogenic center of aegelinol. The pyranocoumarin guest is included within the cylindrical cavity formed by dimeric β-cyclodextrin molecules with a head-to-head arrangement. Crystal structure of aegelinol alone was also determined (a = 6.8921(3) Å, b = 11.4302(9) Å, c = 44.964(3) Å, P212121; R1 = 4.44%) and allowed precise determination of its geometry. Aegelinol crystallizes with three molecules in the asymmetric unit held together by H-bonds and π-stacking interactions.
The ACRF BRF in collaboration with the CSIRO houses a next generation post light sequencer called the Ion Torrent Personal Genome Machine, the worlds first semiconductor-based DNA sequencing technology. The system is based on the detection of hydrogen ions that are released as nucleotides and added during the synthesis of nucleic acid chains that are complementary to a template strand.
International team publishes comprehensive DNA analysis of outbreak strain and 11 related strains in New England Journal of Medicine. An international team of scientists has successfully employed single molecule, real-time (SMRTâ" ¢) DNA sequencing technology from Pacific Biosciences of California, Inc. (NASDAQ: PACB) to provide valuable insights into the pathogenicity and evolutionary origins of the highly virulent bacterium responsible for the German E. coli outbreak. Published online today in the New England Journal of Medicine, the results provide the most detailed genetic profile to date of the outbreak strain, including medically relevant information.. The researchers determined the outbreak strain was a member of the enteroaggregative pathotype of E. coli (EAEC) with serotype O104:H4. The outbreak isolates are distinguished from other O104:H4 strains because they contain genes encoding Shiga toxin 2 (Stx2) and a distinct set of additional virulence and antibiotic resistance factors. ...
TY - THES. T1 - Bioinformatic investigation of the human and Arabidopsis epigenomes. AU - Tonti-Filippini, Julian. PY - 2011. Y1 - 2011. N2 - In a media release (dated 26-June-2000) scientists announced that they had completed the first draft of the human genome sequence. This major scientific milestone required the work of hundreds of people, took a decade to complete, and cost around $US 3,000,000,000. Only a decade later, the same feat could be accomplished by a single laboratory, over a few weeks, and for less than $30,000. In another decade, it is expected that DNA sequencing technology will allow a single technician to sequence a human genome in less than one hour and for an equivalent cost of around $100. DNA sequencing technology is improving so rapidly that the current rate of advance exceeds Moores Law (an observation that computing power doubles every two years). Faced with exponential growth of DNA sequencing information, a data-crisis has manifested as researchers struggle to ...
A research team led by Associate Professor Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL) has developed a sensitive and accurate way of identifying gene copy number variations (CNVs). The method, which is ...