Sophisticated analyses of two clinical trials -- one in the U.S. and the other in the Australia -- suggest that thousands of early preterm births -- those at or before 34 weeks gestation -- could be prevented if pregnant women took daily docosahexaenoic acid (DHA) supplements.. The randomized controlled trials in which pregnant women took daily DHA supplements independently found statistically significant reductions in early preterm birth. The statistical model examined low-, moderate- and high-risk births from mothers supplemented with DHA during pregnancy as compared to placebo controls. The researchers estimated that more than 106,000 high-risk early preterm births could be avoided in the U.S. and about 1,100 could be prevented in Australia each year if pregnant women took daily supplements of the omega fatty acid.. Infants born very preterm often require lifesaving treatments and longer hospitalizations at birth and are at increased risk for additional hospitalizations in the first year of ...
TUESDAY, Aug. 8, 2017 (HealthDay News) -- Sleep disorders during pregnancy may increase the risk of preterm birth, a new study finds.. The California research looked at 2,265 pregnant women who were diagnosed with a sleep disorder, such as insomnia or sleep apnea. They were compared to a control group of pregnant women without a sleep disorder diagnosis but with similar maternal risk factors for preterm birth, such as a previous preterm birth, smoking during pregnancy, or high blood pressure. The rate of preterm birth was 14.6 percent among women with sleep disorders and 10.9 percent among the control group. Preterm birth is defined as delivery before 37 weeks gestation.. The risk of delivery before 34 weeks gestation was more than double among women with sleep apnea and nearly double among those with insomnia, according to the study.. It was published Aug. 8 in the journal Obstetrics & Gynecology.. Treating sleep disorders could help reduce the preterm birth rate, which stands at about 10 ...
The National Institutes of Health (NIH). March 1, 2016. Pregnant women with asthma may be at greater risk of preterm birth when exposed to high levels of certain traffic-related air pollutants, according to a study by researchers at the National Institutes of Health and other institutions.. The researchers observed an increased risk associated with both ongoing and short-term exposure to nitrogen oxides and carbon monoxide, particularly when women were exposed to those pollutants just before conception and in early pregnancy.. For example, an increase of 30 parts per billion in nitrogen oxide exposure in the three months prior to pregnancy increased preterm birth risk by nearly 30 percent for women with asthma, compared to 8 percent for women without asthma. Greater carbon monoxide exposure during the same period raised preterm birth risk by 12 percent for asthmatic women, but had no effect on preterm birth risk for non-asthmatics.. The last six weeks of pregnancy was another critical window for ...
Background Being able to predict preterm birth is important, as it may allow a high-risk population to be selected for future interventional studies and help in understanding the pathways that lead to preterm birth. Objective To investigate the accuracy of novel biomarkers to predict spontaneous preterm birth in women with singleton pregnancies and no symptoms of preterm labour. Search strategy Electronic searches in PubMed, Embase, Cinahl, Lilacs, and Medion, references of retrieved articles, and conference proceedings. No language restrictions were applied. Selection criteria Observational studies that evaluated the accuracy of biomarkers proposed in the last decade to predict spontaneous preterm birth in asymptomatic women. We excluded studies in which biomarkers were evaluated in women with preterm labour. Data collection and analysis Two reviewers independently extracted data on study characteristics, quality, and accuracy. Data were arranged in 2 × 2 contingency tables and synthesised separately
TY - JOUR. T1 - Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms. AU - Engel, Stephanie A Mulherin. AU - Erichsen, Hans Christian. AU - Savitz, David A.. AU - Thorp, John. AU - Chanock, Stephen J.. AU - Olshan, Andrew F.. PY - 2005/7. Y1 - 2005/7. N2 - Background: Preliminary data suggest that common genetic variation in immune response genes can contribute to the risk for spontaneous preterm birth and possibly small-for-gestational age (SGA). Methods: We investigated the relationship of polymorphisms in 6 cytokine genes associated with inflammation-interleukin (IL)1α, IL1β, IL2, IL6, tumor necrosis factor (TNF), and lymphotoxin α (LTA)-with spontaneous preterm and SGA birth in a nested case-control study drawn from a prospective pregnancy cohort. Women were recruited between 24 and 29 weeks gestation at the Wake County and University of North Carolina, Chapel Hill obstetric clinics between February 1996 and June 2000. We inferred haplotypes ...
This study evaluated the consequences of late preterm birth on child growth in the first two years of life as compared to term deliveries in a population-based cohort from a middle-income country. Among the strengths of the study, besides sample size, are the low rates of refusal and loss to follow-up, and the prospective cohort design that allows assessment of temporal relationships.. A key limitation of the study is that most of the confounders studied were self-reported by mothers. Furthermore, in the analyses of late preterm birth and wasting at 12 and 24 months of age, the low number of children born late preterm that were wasted resulted in reduced precision.. Some methodological issues of this study are worthy of being discussed. First, some of the increase in morbidity among late preterm children may be attributable to observation and detection bias, because mothers and medical doctors may be more attentive to monitor symptoms and signs of medical complications and diseases in preterm ...
Secular trends in the prevalence of preterm birth and international comparisons of the rates of preterm birth are difficult to interpret because of differences, both formal and informal, in the registration of extremely preterm births. Accurate estimation of gestational age is another problem in the measurement of preterm birth. Preterm birth is heterogeneous in several ways. It is heterogeneous in terms of the extent to which the birth is preterm (20-27 weeks, 28-31 weeks or 32-36 weeks of gestation); in whether the birth was elective or spontaneous; and among spontaneous idiopathic preterm births, in whether there was preterm labour or premature rupture of the membranes. Case-control study designs taking account of these subgroups have been a recent feature of epidemiologic approaches. The classic social associations of preterm birth--low socioeconomic status, extremes of maternal age, primiparity, being unmarried--apply to extremely preterm and moderately preterm births as well as to the mildly
Results In total, 7.5% (95% CI 7.2 to 7.9) of all spontaneous births were preterm. The prevalence of preterm birth according to the mothers BMI was 7.3% (95% CI 6.9 to 7.7) for normal weight, 7.6% (95% CI 6.4 to 8.9) for underweight, 8.2% (95% CI 7.4 to 9.1) for overweight and 8.3% (95% CI 7.0 to 9.6) for obese women. The risk of spontaneous preterm birth was increased in overweight women compare to normal weight mothers (crude OR 1.15, 95% CI 1.13 to 1.31). After adjustment for marital status and education, increased risks of preterm delivery were found in both overweight (OR 1.18, 95% CI 1.04 to 1.34) and obese women (OR 1.21, 95% CI 1.00 to 1.45). Further adjustment for age, parity, infant sex, smoking and alcohol abuse, reduced the associations to non-significant level. ...
The purpose of the present study was to search for associations between spontaneous preterm birth (sPTB), single nucleotide polymorphisms (SNPs) associated with the apoptotic pathway as triggered by oxidative stress, maternal lifestyle and health status. SNP genotyping [rs7560 for c-Jun N-terminal kinase (JNK), rs9517320 for mammalian STE20-like protein kinase 3 (MST3), rs1049216 for caspase 3 (CASP3)] in the placenta and maternal blood of 300 controls with at-term birth and 43 cases of sPTB was performed. No association was identified in genotype frequencies or combinations of foetal/maternal genotypes between single SNPs and sPTB. The risk of sPTB was significantly reduced by physical activity and significantly increased by current hypertensive diseases, premature rupture of membranes (PROM) or preterm PROM (P-PROM) and previous sPTB. The TT/GA genotype of JNK/CASP3 in maternal blood and maternal health status (current hypertensive diseases, current PROM/P-PROM, previous sPTB) were ...
TY - JOUR. T1 - Progesterone for the prevention of preterm birth. AU - Salati, Jennifer. AU - Caughey, Aaron B.. PY - 2014/1/1. Y1 - 2014/1/1. N2 - Preterm birth is the leading cause of neonatal morbidity and mortality in the United States and is one of the leading causes worldwide, with the highest rates of mortality occurring in those born at less than 32 weeks gestation. A history of preterm birth is one of the strongest risk factors for recurrent preterm delivery; however, early cervical shortening and multiple gestations also confer an increased risk of preterm birth. The precise causal mechanisms underlying the preterm birth pathway are still under investigation; however, available evidence suggests a role of progesterone in preterm birth prevention in certain high-risk populations. Specifically, intramuscular 17-hydroxyprogesterone appears beneficial in women with a prior pretermbirth at less than 37 weeks gestation (relative risk, 0.55; 95% confidence interval, 0.42-74) and preterm ...
Progesterone for the prevention of preterm birth: indications, when to initiate, efficacy and safety Helen Y How, Baha M SibaiDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati, Cincinnati, OH USAAbstract: Preterm birth is the leading cause of neonatal mortality and morbidity and long-term disability of non-anomalous infants. Previous studies have identified a prior early spontaneous preterm birth as the risk factor with the highest predictive value for recurrence. Two recent double blind randomized placebo controlled trials reported lower preterm birth rate with the use of either intramuscular 17 alpha-hydroxyprogesterone caproate (IM 17OHP-C) or intravaginal micronized progesterone suppositories in women at risk for preterm delivery. However, it is still unclear which high-risk women would truly benefit from this treatment in a general clinical setting and whether socio-cultural, racial and genetic differences play a role in patients response to
A baby born at less than 37 weeks of gestation is considered preterm. This occurs more often among black women than white women and is a leading cause of infant morbidity and mortality in the United States. Obesity is associated with intrauterine infections, systematic inflammation, dyslipidemia, and hyperinsulinemia, all of which may increase the risk of preterm birth. In order to investigate the relations of preterm birth with prepregnancy obesity and gestational weight gain, the BUSM researchers used data from the Slone Epidemiology Centers Black Womens Health Study. They compared mothers of more than 1,000 infants born three or more weeks early with mothers of more than 7,000 full-term infants. They examined two types of preterm birth: that indicated for medical reasons (medically-indicated) and that occurring for no known reason (spontaneous).. The researchers found that obesity increased the risk of medically-indicated preterm birth and very early spontaneous preterm birth (,32 weeks), ...
since we know that preterm birth is the most common cause of infant death, and survivors of preterm birth may need special health care or educational interventions in order to thrive and be productive in our workforce.. Looking back: ideally, Alachua Countys preterm birth rate 12.5% (# of preterm births per 100 births) should go down year after year, and the total number of pre-term births should be fewer than observed last year.. We can compare our past or current pre-term birth rate to that of other counties and to the state. But in order to reduce the number of pre-term births, we need to take local action. To guide our interventions, we need to look forward.. Looking forward: Because we know that pre-term births are more common in pregnant women under stress, it is helpful to know where pre-term births cluster in our community, so that we can do what is possible to reduce environmental stress in those neighborhoods. One of the main stressors many women face is domestic violence, thus by ...
New research presented at ACOG 2014 shows that inadequate weight gain in the second trimester is an independent risk factor for spontaneous preterm birth.
Preterm birth is the leading cause of perinatal morbidity and mortality. Risk factors for preterm birth include a personal or familial history of preterm delivery, ethnicity and low socioeconomic status yet the ability to predict preterm delivery before the onset of preterm labour evades clinical practice. Evidence suggests that genetics may play a role in the multi-factorial pathophysiology of preterm birth. The All Our Babies Study is an on-going community based longitudinal cohort study that was designed to establish a cohort of women to investigate how a womens genetics and environment contribute to the pathophysiology of preterm birth. Specifically this study will examine the predictive potential of maternal leukocytes for predicting preterm birth in non-labouring women through the examination of gene expression profiles and gene-environment interactions. Collaborations have been established between clinical lab services, the provincial health service provider and researchers to create an
Objective: Despite decades of research on risk indicators of spontaneous preterm birth (PTB), reliable biomarkers are still not available to screen or diagnose high-risk pregnancies. Several biomarkers in maternal and fetal compartments have been mechanistically linked to PTB, but none of them are reliable predictors of pregnancy outcome. This systematic review was conducted to synthesize the knowledge on PTB biomarkers identified using multiplex analysis. Materials and methods: Three electronic databases (PubMed, EMBASE and Web of Science) were searched for studies in any language reporting the use of multiplex assays for maternal biomarkers associated with PTB published from January 2005 to March 2014. Results: Retrieved citations (3631) were screened, and relevant studies (33) were selected for full-text reading. Ten studies were included in the review. Forty-two PTB-related proteins were reported, and RANTES and IL-10 (three studies) followed by MIP-1 beta, GM-CSF, Eotaxin, and TNF-RI (two ...
A recent study published in Obstetrics and Gynecology has shown potential links between sleep disorders in pregnant women and premature births. Premature birth is defined by the WHO as happening before 37 weeks or 259 days of gestation and plays a large role in neonatal mortality and morbidity. It is estimated that premature birth accounts ...
From: Leanne Martin ,[email protected]> Date: Wed, 03 Feb 1999 14:40:14 PST Fwd Date: Wed, 03 Feb 1999 21:28:49 -0500 Subject: Re: Premature Birth & Abduction? >From: Jim Mortellaro ,[email protected]> >Date: Tue, 2 Feb 1999 15:49:42 EST >To: [email protected] >Subject: Re: Premature Birth & Abduction? >>Date: Tue, 02 Feb 1999 12:13:34 -0800 >>From: Judith Dale ,[email protected]> >>To: UFO UpDates - Toronto ,[email protected]> >>Subject: Re: Premature Birth & Abduction? >>Lets get down to brass tacks here. Why is it happening? What if >>anything, do we need to do to respond? Is it a threat to our >>well-being as humans? Although, I must say, I believe we are so >>much of a threat to ourselves, that an "alien" threat doesnt >>seem much worse to me. >Dear, dear Judith Dale... thank you. A breath of fresh air in >a stale room full of rhino juice and Gripple Dripple... Finally! >I think I love you, Gday Judith, Jim & List, Yes! Lets please get down to brass tacks ...
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Health, ...WEDNESDAY April 6 (HealthDay News) -- Progesterone treatment lowers t...Progesterone is a naturally occurring hormone that plays an important ...This study included 458 women with a short cervix (10-20 millimeters) ...The rate of preterm delivery at less than 33 weeks pregnancy was 8.9 p...,Progesterone,Treatment,Cuts,Preterm,Birth,Risk,in,Certain,Women,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Preterm birth is the most common cause of death and harm to newborn babies. In the USA, about one in every 10 babies is born preterm, before the 37th week of pregnancy. Preterm birth is more common in African American women, affecting about one in every seven babies. In Europe, about 1 in 20 births is preterm, and in African countries, almost 1 in 5 babies are delivered before 37 weeks.. Babies born early may have difficulties at birth and health problems during early childhood. They are more likely to die during their first year and to experience long-term disabilities such as cerebral palsy, epilepsy, blindness, and hearing loss. Reducing the numbers of preterm births is therefore important to pregnant women and their families, and is a global health priority.. Progestogens are medications that are similar to the pregnancy hormone progesterone. They are thought to help prevent preterm birth in women who may be at higher risk of an early birth. Women who have had a preterm birth in a previous ...
The MoD is on a quest to reduce preterm births and because roughly half of them are from unknown causes, a good deal of the research they fund is to get at the root causes and potential prevention of those "unknowns." Preeclampsia is - at last count - the number one KNOWN cause of preterm birth, around 15%. The March of Dimes does fund *some* research in preeclampsia, recognizing its role in this problem, and was an active participant in a PE workshop at NIH 3 years ago (I was a presenter there on behalf of the PF). I will also find out the current status and amount of that research, relative to the overall pot of money being spent in this area. I believe that if you are donating to them, you should understand how much of your dollar is targeted to the issues you care about ...
A search of the published and unpublished medical and health economics literature by us revealed that relatively few studies have estimated the long-term economic impact of preterm birth.18,19,29 Moreover, the studies that have been conducted to date were based on relatively small samples of infants and frequently violated current methodologic requirements of health economic evaluation.19 Our study generated a mean cost difference of £14 614 (US $22 798) when infants born at ,28 weeks gestational age were compared with term infants and £11 958 (US $18 654) when infants born at 28 to 31 weeks gestational age were compared with term infants. Moreover, these cost differences had been calculated after a multivariate analysis controlled for a wide range of clinical and sociodemographic confounding factors including birth weight for gestational age, year of birth, sex, survival period, maternal age and morbidity, multiplicity of birth, and a comprehensive profile of childhood diseases.. The major ...
Five researchers from four states are investigating how genetics and infections interact to cause preterm birth as well as how proteins and hormones regulate a healthy pregnancy, all with the goal of giving more babies a healthy start in life, the March of Dimes announced today.. The researchers will study the role that fetal fibronectin, a protein, plays in triggering premature rupture of the membranes; and how progesterone, a hormone that has been shown to prevent preterm birth in some women, helps a healthy pregnancy. Nearly half a million babies - one out of every nine - are born too soon each year in the United States. Preterm birth is a serious health problem that costs the nation $26 billion annually. It is the leading cause of neonatal death, and babies who survive an early birth have increased risks of lung disease, cerebral palsy and intellectual and developmental disabilities, problems that can affect their health throughout their lives. In 2011, the US preterm birth rate dropped to ...
Preterm birth is associated with adverse renal health outcomes including hypertension, chronic kidney disease, and an increased rate of progression to end-stage renal failure. This review explores the antenatal, perinatal, and postnatal factors that affect the functional nephron mass of an individual and contribute to long-term kidney outcome. Health-care professionals have opportunities to increase their awareness of the risks to kidney health in this population. Optimizing maternal health around the time of conception and during pregnancy, providing kidney-focused supportive care in the NICU during postnatal nephrogenesis, and avoiding accelerating nephron loss throughout life may all contribute to improved long-term outcomes. There is a need for ongoing research into the long-term kidney outcomes of preterm survivors in mid-to-late adulthood as well as a need for further research into interventions that may improve ex utero nephrogenesis. ...
Genetic mutations in the enzyme methylenetetrahydrofoloate reductase (MTHFR) and coagulation protein Factor V appear to have significant association with blood clots and tissue injury to the placenta and developing baby, ...
Curbing Premature Birth. A study published in the journal Science Translational Medicine reports that scientists from the Stanford University have identified a molecule in the uterus that can be blocked to delay or halt premature birth. The identification of the molecule can help in curbing deaths and disability in the newborns.. More than 10% of all infants are born prematurely after less than 37 weeks of pregnancy whereas nearly 3% are born quite prematurely after less than 31 weeks of pregnancy. Normal pregnancies last between 38 and 42 weeks. However, there is a mystery behind the labour process which begins in the womb. At present, there is no effective treatment for premature labour. Previous researches have shown that the calcium levels of muscle cells within the uterus walls help control womb contractions.. In this case, researchers focused on TRPV4 molecule that controls the flow of calcium into cells. Scientists found that uterine tissue from pregnant women possessed higher levels of ...
Sometimes, theres just no explanation for why a woman has her baby early. However, certain factors play a part in bringing a baby into the world earlier than expected. If youre pregnant with twins or triplets, you may have your babies earlier than if you were pregnant with one. If youve already had a premature baby, theres a slightly higher chance of you having another premature birth. Social factors play a part, too. Girls under 16 and who have little support are the most likely to have a premature baby. A womans age, class, education and the type of job she does, if it involves long hours and strenuous activity, can affect her chances of having a baby early. Smoking, taking drugs and being underweight are all linked with problems that can cause premature birth.. ...
Our client, the March of Dimes, delivered its first report card to America yesterday. And we dont have a passing grade when it comes to the number of premature births that occur in this country. Premature births can lead to...
Smoking ban cuts premature births, BBC News has reported. Despite the BBC News headline, this research only showed an association between the smoking ban and a reduction in premature births. It didnt show direct cause and effect…
The bottom line is that women who were treated had about a 30 percent reduction in having a pre-term delivery compared to a placebo, said Dr. Nancy Green, medical director of the March of Dimes, and this was a very well-designed clinical study. The results are good news to clinicians because the causes of pre-term birth are poorly understood and researchers have found few interventions effective in preventing ever-increasing rates of premature delivery. The efficacy of 17P is particularly surprising because it is an old drug that has languished on storage shelves for decades, researchers said. Because the patent on the drug has long-expired, 17P is of little interest to the pharmaceutical industry. The study required public funding in order to resurrect it from the dust heap of clinical research. This is a beautiful study. The network of institutions working together with public health support made it possible, Dr. Emile Papiernik of the Assistance Public Hospital in Paris, told United ...
Preterm birth, i.e., delivery more than 3 weeks before term, affects annually an estimated 13,000,000 newborn infants and rates are increasing1. Only in the USA, about 500,000 infants are born preterm each year and of those, 80,000 are delivered very preterm (more than 8 weeks before the expected date). Without effective care, the number of deaths among very preterm infants would equal that of major causes of death in adults, such as Alzheimers disease or essential hypertension. While mortality after preterm birth was high until a few decades ago, advances in perinatal medicine have resulted in almost universal survival2 so that the concept of prematurity nowadays is shifting from being a pregnancy complication to a common developmental basis for a whole and new generation of young adults. Although this progress is very welcome for women delivering preterm, their infants and their families, there is an increasing concern because preterm birth has been identified as an emerging risk factor for ...
Preterm Birth and PROM Testing Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2018 - 2026. Global Preterm Birth and PROM Testing Market: Overview This report analyzes the current and future scenario of the global preterm birth and PROM testing market. Increase in preterm births, rise in demand for point-of-care testing
We investigated the association between the risk of preterm delivery and each metabolic gene of glutathione S-transferases mu 1 (GSTM1), theta 1 (GSTT1) and cytochrome P450IA1 (CYP1A1) along with exposure to particulate matter <10 μm (PM10). This study was assumed to identify gene-environment interaction that increases the risk of preterm delivery. A case-control study was carried out on 117 women with preterm deliveries and 118 women with term deliveries in Seoul, Korea. Logistic regression analyses were performed to explore the impact of each gene, PM10 exposure and their interaction on the risk of preterm birth. The risk of preterm birth was associated with the GSTM1 null genotype only. Exposure to high levels of PM10 (≥75th percentile) during the third trimester of pregnancy was associated with an increased risk of preterm birth when compared to low-level exposure to PM10 (<75th percentile). We found that exposure to high levels of PM10 during the third trimester in the presence of ...
Premature birth affects 450,000 U.S. babies each year and is the leading cause of newborn deaths. But in about half of cases, doctors never figure out what triggered premature labor in the pregnant mom.. Now, theres a new clue: A Stanford study, published today, gives important details of how the microbiome - the bodys community of bacteria - behaves in women whose pregnancies go to the full 40-week term, and whats different in women whose babies come three weeks, or more, early. A specific pattern of vaginal bacteria was linked to greater risk of preterm delivery, and the longer the pattern persisted, the greater the risk, the study found.. The work is one piece of a larger effort by the March of Dimes Prematurity Research Center at Stanford to bring experts from many branches of science together to work on preterm birth. The researchers collected weekly bacterial samples throughout pregnancy from four body sites for 49 pregnant women, of whom 15 delivered prematurely. Patterns of vaginal ...
This essential guide for parents of premature babies covers gestational age, premature birth risk factors, premature labour and premature development.
We proposes to examine the hypotheses that maternal exposure to air pollutants during pregnancy is associated with an increased risk of very preterm birth (VPTB,
Arroyo V, Díaz J, Ortiz C, Carmona R, Sáez M, Linares C. 2016. Short term effect of air pollution, noise and heat waves on preterm births in Madrid (Spain). Environ Res 145:162-168, PMID: 26706568, 10.1016/j.envres.2015.11.034. Auger N, Hansen AV, Mortensen L. 2013. Contribution of maternal age to preterm birth rates in Denmark and Quebec, 1981-2008. Am J Public Health 103(10):e33-e38, PMID: 23947312, 10.2105/AJPH.2013.301523. Benmarhnia T, Rey L, Cartier Y, Clary CM, Deguen S, Brousselle A. 2014. Addressing equity in interventions to reduce air pollution in urban areas: a systematic review. Int J Public Health 59(6):933-944, PMID: 25255913, 10.1007/s00038-014-0608-0. Birth Cohort Public Use File, 1999-2003 2015, https://www.cdc.gov/nchs/data_access/vitalstatsonline.htm [accessed 10 November 2015]. Blumenshine P, Egerter S, Barclay CJ, Cubbin C, Braveman PA. 2010. Socioeconomic disparities in adverse birth outcomes: a systematic review. Am J Prev Med 39(3):263-272, PMID: 20709259, ...
Several hospitals and advocacy groups have made recommendations that warrant discussion as a good first step in the effort to help reduce premature births, a Daily Herald editorial says..
We often get questions from women wondering whether they are at risk to have a premature baby. What makes some women give birth early? We dont always know what causes preterm labor and premature birth. However, there are some things that we do know make it more likely. These things are called risk factors. Having a risk factor doesnt mean that you will definitely have preterm labor or give birth early. But it may increase your chances ...
Researchers from the University of Adelaide have successfully tested a drug that is showing some early promise in efforts to prevent pre-term birth.
As we approach Mothers Day, many of us who are lucky enough to be called "mommy" will remember the birth stories of our children … the contractions, the exhaustion … all of which are followed by the elation of seeing our newborns face for the first time. But if you have experienced preterm labor and a premature birth, you know that all of these emotions will quickly be overshadowed by the fear of a premature baby. After two full-term births, my third child unexpectedly came a month early, and I now know firsthand just how frightening this can be. Thankfully, he was fine, but this is not always the case ...
Preterm birth (delivery at less than 37 weeks of gestation) is the leading cause of infant mortality worldwide. So far, the application of animal models to understand human birth timing has not substantially revealed mechanisms that could be used to prevent prematurity. However, with amassing data implicating an important role for genetics in the timing of the onset of human labor, the use of modern genomic approaches, such as genome-wide association studies, rare variant analyses using whole-exome or genome sequencing, and family-based designs, holds enormous potential. Although some progress has been made in the search for causative genes and variants associated with preterm birth, the major genetic determinants remain to be identified. Here, we review insights from and limitations of animal models for understanding the physiology of parturition, recent human genetic and genomic studies to identify genes involved in preterm birth, and emerging areas that are likely to be informative in future
Preterm birth is a major cause of infant morbidity and mortality, yet little is known about the long-term risk of mortality and overall health among persons born preterm. To determine the long-term effects of preterm birth on survival, reproduction, and next-generation preterm birth, a population-based, observational, longitudinal study was conducted using registry data on births and deaths from for more than 1 million men and women in Norway.. ...
The rate of preterm births and low birth weight have increased and are the leading cause of newborn deaths in the United States. The authors caution that cuts to Medicaid would seriously jeopardize infant lives.. Preterm birth refers to a birth that occurs more than three weeks before the baby is due, or more specifically, one that occurs before the 37th week. Preterm birth complications were found to be the leading cause of death among children less than 5 years of age and resulted in approximately 1 million deaths in 2015 worldwide. According to the World Health Organization, three-quarters of these deaths could have been saved with cost-effective interventions.. ...
A link between induced abortion and premature births - and associated health complications - is supported by a new study from Finland. The more abortions a woman has had before giving birth, the more likely she is to give birth prematurely, the BBC reports.
7. [+36, -6] Youre safe to give birth past the 34 week mark. You dont need to wait for the full 40 weeks. The lungs are done developing by 34 weeks so you can give birth any time after that. There are a ton of healthy babies that are born before that too because of advancement in medical technology. Mothers already blame themselves very hard when they give premature births so I hope she doesnt read some of the comments here.. congratulations ...
Ten percent of all births are premature. What can cause premature birth? What to watch for -- and youll find out if youre at risk and what you can do!
A new study provides additional support for treatment with vaginal progesterone to reduce the risk of preterm birth, neonatal complications and infant death in pregnant women with a short cervix. A shortened cervix is the most powerful predictor of preterm birth ...
One million babies worldwide died this year because they were born too soon, according to the March of Dimes. The Empire State Building towers were lit in purple last night in honor of the first-ever World Prematurity Day. This day is a call to raise awareness efforts to reduce death and disability caused by premature birth. An estimated 13 million babies are born early every year around the globe, including more than half a million in the United States, according to March of Dimes. Learn more on the World Prematurity Day Facebook page, run a global alliance of partners including March of Dimes, the European Foundation for the Care of Newborn Infants, Australias National Premmie Foundation and Africas Little Big Souls. ,,Read more on maternal and infant health. ...