Background/Purpose: Autoimmune conditions are associated with an increased risk of adverse pregnancy complications and outcomes, suggesting that pregnancy complications may mediate the excess risk. We performed a causal mediation analysis to quantify the mediated effects of autoimmune conditions on adverse pregnancy outcomes.. Methods: We queried a retrospective California birth cohort created from linked birth certificates and hospital discharge summaries. From 2,963,888 births, we identified women with rheumatoid arthritis, systemic lupus erythematosus, psoriasis and inflammatory bowel disease. Pregnancy complications included preeclampsia/hypertension, gestational diabetes and infection in pregnancy. Adverse pregnancy outcomes were preterm birth, cesarean delivery and small for gestational age. We performed a causal mediation analysis to estimate the total effects of each autoimmune condition and adverse pregnancy outcome, and the indirect effects of each pregnancy complication.. Results: ...

How to Cite: Tennakoon, V., Weerasekera, D.S. and Yasawardene, S.G., 2012. Successful pregnancy outcomes following in-vitro fertilization in infertile couples with high levels of antisperm antibodies. Sri Lanka Journal of Obstetrics and Gynaecology, 32(2), pp.47-48. DOI: http://doi.org/10.4038/sljog.v32i2.3981 ...

To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality ...

|jats:p||jats:italic|Objectives|/jats:italic|. Hepatitis B virus (HBV) was believed to have minimal impact on pregnancy outcomes apart from the risk of perinatal transmission. In more recent years, there have been reports of adverse associations, most consistently preterm birth (PTB), but this is in the context of high rates of caesarean section. The aim of this study was to explore the association of HBV on pregnancy outcomes in marginalized, low-income populations on the Myanmar-Thailand border.|jats:italic| Methods|/jats:italic|. HBsAg positive (+) point of care rapid detection tests results were confirmed by immunoassays. Women with a confirmed HBsAg status, HIV- and syphilis-negative at first antenatal care screening, singleton fetus and known pregnancy outcome (Aug-2012 to Dec-2016) were included. Logistic regression analysis was used to evaluate associations between HBV group (controls HBsAg negative, HBsAg+/HBeAg-, or HBsAg+/HBeAg+) and pregnancy outcome and comorbidity.|jats:italic| Results|

The purpose of this study was to compare pregnancy outcomes for teenagers who received prenatal care at a teen-only health clinic versus pregnancy outcomes for teenagers who received prenatal care at a traditional obstetrical/gynecological clinic. In addition, this study explored the relationship between maternal demographic characteristics and pregnancy outcomes. Data were collected through retrospective chart reviews for a total sample of 60 cases (30 from the teen-only clinic and 30 from the traditional clinic). Inclusion criteria were 1) female who was between the age of 1 0 and 19 years when she presented for prenatal care, 2) at least 8 weeks post-partum at the time of the study, 3) prenatal records available in the chart, and 4) delivery record available in the chart. Data on pregnancy outcomes included maternal total weight gain, maternal body mass index, number of weeks at start of prenatal care, number of prenatal appointments attended, post-partum appointment attendance, ...

Although the general statistical advice is to keep continuous exposure variables as continuous in statistical analyses, categorisation is still a common approach in medical research. In a recent paper from the Hyperglycaemia and Adverse Pregnancy Outcome (HAPO) Study, categorisation of body mass index (BMI) was used when analysing the effect of BMI on adverse pregnancy outcomes. The lowest category, labelled underweight, was used as the reference category. The present paper gives a summary of reasons for categorisation and methodological drawbacks of this approach. We also discuss the choice of reference category and alternative analyses. We exemplify our arguments by a reanalysis of results from the HAPO paper. Categorisation of continuous exposure data results in loss of power and other methodological challenges. An unfortunate choice of reference category can give additional lack of precision and obscure the interpretation of risk estimates. A highlighted odds ratio (OR) in the HAPO study is the OR

TY - JOUR. T1 - A description of the methods of the Nulliparous Pregnancy Outcomes Study. T2 - Monitoring mothers-to-be (nuMoM2b). AU - Haas, David. AU - Parker, Corette B.. AU - Wing, Deborah A.. AU - Parry, Samuel. AU - Grobman, William A.. AU - Mercer, Brian M.. AU - Simhan, Hyagriv N.. AU - Hoffman, Matthew K.. AU - Silver, Robert M.. AU - Wadhwa, Pathik. AU - Iams, Jay D.. AU - Koch, Matthew A.. AU - Caritis, Steve N.. AU - Wapner, Ronald J.. AU - Esplin, M. Sean. AU - Elovitz, Michal A.. AU - Foroud, Tatiana. AU - Peaceman, Alan M.. AU - Saade, George R.. AU - Willinger, Marian. AU - Reddy, Uma M.. PY - 2015/4/1. Y1 - 2015/4/1. N2 - Objective The primary aim of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be is to determine maternal characteristics, which include genetic, physiologic response to pregnancy, and environmental factors that predict adverse pregnancy outcomes. Study Design Nulliparous women in the first trimester of pregnancy were recruited into an ...

There are two very common concerns for couples that are considering in vitro fertilization: Unhealthy embryos result in failed pregnancies, which can lead to frustration, extra cost and even depression for IVF couples and multiple embryo transplants increase the risk of complications for both mother and baby. With more and more couples seeking out the assistance of in vitro fertilization to achieve pregnancy, researchers have been looking for more ways to help improve the outcomes of those pregnancies. A new technology known as Eeva (Early Embryo Viability Assessment) may soon help with both of these concerns.. The new technology, shared by a team of investigators at the Pacific Fertility Center (USA) and at the Hewitt Fertility Center in Liverpool (UK) at Fertility 2013, will hopefully result in more favorable pregnancy outcomes and reduce the requirement to move more than one embryo at a time into the womb. This would reduce the number of multiple pregnancies, which have been cited as one of ...

The haemodynamic changes of pregnancy can have a negative impact on maternal cardiac health, especially in women with pre-existing cardiac disease. In the most recent Confidential Inquiries into Maternal Mortality in the United Kingdom, heart disease was found to be the most common indirect cause of maternal death during pregnancy.1 Pregnancy counselling and management for women with heart disease is being increasingly recognized as an important aspect of their overall cardiac care. With increasing awareness, there has been a growing body of research focused on pregnancy outcomes and risk stratification. There have also been new initiatives to improve clinical care, such as the 2011 European Society of Cardiology (ESC) guidelines on the management of cardiovascular disease during pregnancy.2 While our current understanding of pregnancy risk assessment and management has improved over the past 20 years, many questions can only be answered by collaborative efforts. ...

Objective: To test the hypothesis that women screened for psychosocial factors, including partner abuse, as recommended by the American College of Obstetricians and Gynecologists would have higher neonatal birth weight, longer gestational age at delivery, higher Apgar scores, and fewer maternal complications. Methods: We evaluated a universal psychosocial screening intervention using a retrospective cohort (n=881 prenatal care patients). Pregnancy outcomes among patients screened beginning in 2008 (n=464) were compared with outcomes among women receiving care before universal screening was implemented (n=417). Data were obtained from medical records between 2007 and 2009. Multivariable logistic regression and analysis of covariance were used to estimate the association between screening and pregnancy outcomes among singleton births adjusting for confounders (prior preterm births, insurance, and mode of delivery). Results: Screened women were less likely than women not universally screened to have low

Results: There was a statistically significant association between exposure to physical violence during pregnancy and preterm birth (PTB) or low birth weight (LBW). After adjustment for age, education, occupation, body mass index (BMI), haemoglobin level, previous adverse pregnancy outcomes, the pregnant women who were exposed to physical violence during pregnancy were five times more likely to have PTB (AOR = 5.5; 95%CI: 2.1-14.1) and were nearly six times more likely to give birth to a child of LBW (AOR = 5.7; 95%CI: 2.2-14.9) as compared to those who were not exposed to physical violence ...

The existing research on pregnancy outcomes for women with intellectual and developmental disabilities (IDD) is sparse. This study analyzed the 2010 Healthcare Cost and Utilization Project Nationwide Inpatient Sample and compared deliveries among women with IDD (n = 340) to the general obstetric population. Women with IDD had longer hospital stays and were more likely to have Caesarean deliveries in contrast to other women. Rates of adverse pregnancy outcomes were elevated for women with IDD across a range of measures, including early labor, preterm birth, and preeclampsia, and their infants were more likely to have low birth weight, even after adjusting for age, race, ethnicity, and insurance type. Targeted interventions are needed to address these deleterious outcomes.

Abstract Background: Household air pollution (HAP) exposure has been linked to adverse pregnancy outcomes. Objectives: A randomized controlled trial was undertaken in Ibadan, Nigeria to determine the impact of cooking with ethanol on pregnancy outcomes. Methods: Three-hundred-twenty-four pregnant women were randomized to either the control (continued cooking using kerosene/firewood stove, n = 162) or intervention group (received ethanol stove, n = 162). Primary outcome variables were birthweight, preterm delivery, intrauterine growth restriction (IUGR), and occurrence of miscarriage/stillbirth. Results: Mean birthweights for ethanol and controls were 3076 and 2988 g, respectively; the difference, 88 g, (95% confidence interval: − 18 g to 194 g), was not statistically significant (p = 0.10). After adjusting for covariates, the difference reached significance (p = 0.020). Rates of preterm delivery were 6.7% (ethanol) and 11.0% (control), (p = 0.22). Number of miscarriages was 1(ethanol) vs. 4 ...

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Pregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes as Predictors of Increased Risk Factors for Cardiovascular Disease (U10) NOT-HL-12-154. NHLBI

Adverse pregnancy outcomes (APOs)-including pre-term birth, pre-eclampsia, and intrauterine growth restriction-are common interrelated disorders caused by placental dysfunction and maternal vascular abnormalities (endothelial activation, inflammation, and vasospasm) that occur in approximately 10% to 20% of pregnancies. Women who experience APOs are at increased risk for future cardiovascular disease (CVD). APOs are associated with increased risk of development of hypertension, left ventricular hypertrophy/dysfunction, vascular dysfunction, and renal dysfunction. The vascular abnormalities that are present during an APO also underlie common, difficult-to-treat forms of CVD in women as they age (e.g., cardiac microvascular dysfunction, heart failure with preserved ejection fraction), suggesting shared mechanistic pathways for APOs and CVD. Here, the authors synthesize the current information and knowledge gaps regarding the progression from APO to CVD. Understanding the risk factors for and ...

Inkster , M E , Fahey , T P , Donnan , P T , Leese , G P , Mires , G J & Murphy , D J 2006 , Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus : systematic review of observational studies , BMC Pregnancy and Childbirth , vol. 6 , 30 . https://doi.org/10.1186/1471-2393-6- ...

Comparison of adverse pregnancy outcome between teenage and adult women at a tertiary hospital in South Africa., ME Hoque, OA Towobola, TJ Mashamba, T Mono

In this study, women with AS showed higher risk for CS than those without AS, but other maternal and foetal outcomes were comparable, including LBW, after adjusting for the number of foetuses.. The results of the present study are in line with the aforementioned studies of AS and pregnancy. The previous retrospective case-control study with 20 pregnant women with AS demonstrated that pregnancy outcome of patients with AS was not different from that of healthy control subjects, except for older maternal age and higher rate of female foetuses in women with AS [17]. In addition, in the retrospective study involving 12 pregnant women with AS, pregnancy outcome was not significantly affected by the disease [18]. Similarly, a retrospective study including a cohort of 939 patients from the AS International Federation Societies in USA, Canada and Europe showed favourable pregnancy and neonatal outcomes in women with AS [19]. However, a recent nationwide population-based case-control study in Sweden was ...

Childcare providers are overwhelmingly women of childbearing age. Occupational risks in this sector include exposure to biological (infectious) or physical (standing, carrying loads) hazards, many of which are associated with adverse pregnancy outcomes such as children with congenital...

Introduction: Although numerous studies have depicted the association between adverse pregnancy outcomes and the future fertility status, this relationship has not b...

This study aims at investigating the effects of maternal depressive symptomatology on pregnancy outcomes and newborn development. How paternal psychopathology is involved in the association will also be explored. This is a three-year prospective cohort study. Three versions of questionnaires (the mother, the father, and the infant) will be developed first. For parents, data on self-reported symptomatology such as depression, anxiety, and stress will be collected, while for infants, maternal report on newborn development will be measured. Then, two medical centers and two regional hospitals will be selected. All pregnant women who undergo a first-trimester prenatal visit, who plan to carry the baby till term, and whose spouse is also willing to participate will be invited to join our study. We expect to recruit a total of 194 pairs of depressive mothers and her spouses and 278 pairs of non-depressive mothers and her spouses in our study. After the informed consent is obtained, one baseline ...

Periodontitis and Adverse Pregnancy Outcomes Oral Health and General Health - What are the Connections? Continuing Education Course dentalcare.com

Despite large numbers of asylum seekers, there is a lack of evidence on pregnancy outcomes and obstetric care of asylum seeking women in Germany. Cross-sectional study (2010-2016) using administrative data of the main referral hospital for pregnant asylum seekers of the reception center of a large federal state in South Germany. Inclusion criteria: women aged 12-50 years, admitted in relation to pregnancy, childbirth or post-partum complications. Outcomes: differences between asylum seekers and residents in the prevalence of high-risk pregnancy conditions, abortive outcomes/stillbirths, peri- and postnatal maternal complications, neonatal complications, and caesarean sections. Analysis: odds ratios (OR) and 95% confidence intervals (CI) obtained by single and multiple logistic regression analysis. Attributable fractions among the exposed (Afe) and among the total population (Afp) were calculated for selected outcomes. Of 19,864 women admitted in relation to pregnancy, childbirth or post-partum

The study showed that the risk of premature birth, microcephaly, and hyperemesis was higher for women with ED of any type. Any form of ED increased the risk of premature delivery with the highest risk for women with anorexia nervosa (60%), followed by unspecified ED (40%) and bulimia (40%). The risk of very preterm birth was highest in bulimia, at 70%, but all three subtypes had a 70% to 90% increased risk of induced preterm birth for medical reasons rather than spontaneous preterm birth ...

Atul Kumar Singh, Anurag Srivastava, M Dabral, SB Gupta.Assessment of the effect of Antenatal checkups and IFA supplementation on pregnancy outcome.NATIONAL JOURNAL OF MEDICAL AND ALLIED SCIENCES 2012;1(1):6-10 ...

TY - JOUR. T1 - Clustering of U.S. women receiving no prenatal care. T2 - Differences in pregnancy outcomes and implications for targeting interventions. AU - Taylor, Cathy R.. AU - Alexander, Greg R.. AU - Hepworth, Joseph T.. PY - 2005/6/1. Y1 - 2005/6/1. N2 - Objectives: Prenatal care is an established mechanism for identifying and managing risk factors impacting pregnancy outcomes. Despite aggressive efforts in the United States (US) to assure that all women begin care in the first trimester, every year about 70,000 women in the US receive no care prior to delivery. We hypothesized that US women receiving no prenatal care comprise clusters (subgroups) with distinctive behavioral, socio-demographic, and medical risks and that birth outcomes differ among the clusters. Methods: White, Black, and Hispanic women (n= 126,220) receiving no prenatal care and delivering a live, singleton infant were identified from linked birth and death certificates for years 1995 through 1997. Cluster analysis was ...

HSS releases study findings regarding women with lupus and good pregnancy outcomes., Pioneering Study Finds Most Women with Lupus can Have Good Pregnancy Outcomes, Identifies Risk Factors Linked to Poor Outcomes

Promising research led by investigators at Hospital for Special Surgery may offer hope for women with lupus who once thought that pregnancy was too risky.

Many studies have investigated factors, often in relative isolation from confounders, and usually in association with adverse pregnancy outcome. We are not aware of any studies using a similar approach to that employed in the present study. Previous evidence of an association between a factor and adverse outcome cannot be extrapolated to indicate that the same variable reduces the likelihood of an uncomplicated pregnancy, but it may support biological plausibility. For example, (lower) maternal age was not included in the final list of variables associated with uncomplicated pregnancy in our study, despite many studies linking advanced maternal age to adverse pregnancy outcomes.14 15 Although it might seem intuitive that improvable factors related to diet, blood pressure, heart rate, weight, and smoking would predict uncomplicated pregnancy, the evidence from well conducted prospective cohort studies has been lacking to date.. The association between obesity and adverse perinatal outcome has ...

Adverse birth outcomes are associated with infant morbidity and mortality and with an increased likelihood of type 2 diabetes, hypertension, and cardiovascular disease in adulthood. Socioeconomic status (SES) is one of the most reliable predictors of health disparities, and although the association between SES and birth outcomes has been studied previously, this is, to our knowledge, the first review that encompasses several dimensions of SES and their influence on birth outcomes in a single article. Our review indicates that education, income, neighbourhood SES, and occupation ...

I always say its never over til the fat lady sings. But that doesnt mean I cant see that fat lady getting ready to get on stage...I can also hear her warming up, running through a few scales too. So, my suspicions were pretty much confirmed about why I didnt get my results yesterday. My results were…

99768 avhandlingar från svenska högskolor och universitet. Avhandling: Folate, Hormones and Infertility Different factors affecting IVF pregnancy outcome.

While antiretroviral therapy in pregnancy reduced vertical transmission, it also increased the frequency of several adverse birth outcomes compared with ...

Being on PrEP does not reduce male fertility or subsequent pregnancy outcomes, according to a new study, which also saw high adherence rates....

Centers for Disease Control and Prevention. Another cool fact. Your first twins ultrasound is usually achieved at about 12 weeks; you might have a ;re-pregnancy earlier for various reasons one being to verify gestation. The primary 13 weeks are often called the First Trimester. These being pregnant tests are very sensitive and really accurate, a positive take a look at means you are definitely childbirth educator certification canada. Be sure to talk to your healthcare provider pregnancyy the possible uncomfortable side effects and complications of the kind of process youll have. i am precisely the identical i am 17 weeks tmoz imporve im hardly displaying, am undecided if i have observed a distinction in my breats both sounds mad however i am small chested. I had these for bout 2 weeks now and when I do bleed its gentle. Participation on this website by a party does pre-pregnancy nutrition can improve pregnancy outcomes imply endorsement of another social gatherings content, merchandise, or ...

Pregnancy outcomes are improving among women with systemic lupus erythematosus but are still worse than those of women without the condition.

In an earlier publication, it was shown that consumption of tapwater during the first trimester of pregnancy was associated with a risk of spontaneous abortion among women who attended three prenatal clinics located in northern California between September 1981 and June 1982. Evidence for biased recall was presented. This report demonstrates that the association is limited to women interviewed by telephone and is not observed among those who completed a mail questionnaire. The possibility that the association among women interviewed by telephone is causal and that the lack of association among mail respondents is due to bias, confounding, or apparently chance fluctuations is shown to be unlikely. For instance, the probability is low that, among mail respondents, cases underreported exposure as compared with controls or that random errors were common enough to camouflage a true effect. Demographic differences between mail and telephone respondents also do not explain the results. Interviewers ...

As the authors acknowledge, information about disease activity, which is a key variable in the equation of the choice of therapy and outcomes of mother and child, was not recorded; further commentary regarding its impact on the different outcomes of the groups is merited. It is reasonable to hypothesize that patients may be receiving a thiopurine owing to more severe disease, and that this disease severity may also affect pregnancy outcomes. In fact, what was not measured may count as much as what was accounted for in the cohort. Disease activity has been related to birth outcomes and is a factor in therapy choice, and thus a confounder, by definition, of the differences found between the groups. Therefore, the lack of a difference in pregnancy and fetal outcomes in the three groups of patients with IBD does not necessarily mean that thiopurines are not independently associated with adverse outcomes. However, one would suspect that women with more severe disease activity would be in one of the ...

Pregnancy outcome and weight gain recommendations for the morbidly obese woman. Obstet Gynecol. 1998 Jan;91(1):97-102.Click here to read

Handler, A. and Rosenberg, D. (1992), Improving Pregnancy Outcomes: Public Versus Private Care for Urban, Low-Income Women. Birth, 19: 123-130. doi: 10.1111/j.1523-536X.1992.tb00669.x ...

Communications Director, AgriSafe Network. Pregnancy and fertility are often not considered when women assume farm tasks. Pesticide and other chemical exposures, zoonotic diseases and heavy lifting particularly during childbearing years, present challenges. ...

Pathak, Sangeeta (2010) Morphological and histological placental characteristics in relation to pregnancy outcome in an unselected population. Doctoral thesis, University of East Anglia. ...

Background: Imprisoned pregnant women constitute an important obstetric group about whom relatively little is known. This systematic review was conducted to identify the risk factors associated with adverse pregnancy outcome present in this group of women. Methods: The review was conducted according

A study led by Hospital for Special Surgery researchers has demonstrated that women who have a specific type of antibody that interferes with blood vessel function are at risk for adverse pregnancy outcomes and that other ...

SYDNEY, AUSTRALIA - Women at high risk of early preeclampsia who show signs of abnormal hemodynamic function earlier in pregnancy may be more likely to have adverse pregnancy outcomes, new data suggest.

(2013) Edvardsson et al. BMC Public Health. BACKGROUND: Overweight and obesity in pregnancy increase the risk of several adverse pregnancy outcomes. However, both mothers and fathers health play an important role for long-term health outco...

Irish drugs and alcohol research, data, policy and sources of evidence on prevention, treatment, rehabilitation, crime and consequences.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...

Background: Placental malaria (PM) causes adverse pregnancy outcomes in the mother and her foetus. It is difficult to study PM directly in humans due to ethical challenges. This study set out to bridge this gap by determining ...

TY - JOUR. T1 - Pregnancy outcomes following placement of elective, urgent and emergent cerclage. AU - Nelson, Latasha. AU - Dola, Thao. AU - Tran, Thuc. AU - Carter, Margaret. AU - Luu, Henry. AU - Dola, Chi. PY - 2009/11/9. Y1 - 2009/11/9. N2 - Objective. To describe pregnancy outcomes following elective history-indicated, urgent ultrasound-indicated or emergent physical-exam indicated cerclage placement. Materials and Methods.Study design was retrospective chart review. Women with singleton gestation and cervical cerclage were categorised into: elective, urgent and emergent group. Results.One hundred and thirty-three women were included; 89 in elective, 26 in urgent and 18 in emergent group. Difference was detected when elective and urgent groups were compared with emergent group for: gestation at delivery 35.9 ± 5.1 vs. 34.2 ± 5.9 vs. 29.3 ± 7.2 weeks, respectively, P , 0.05, delivery beyond 36 weeks, 73.9, 57.7vs. 23.5, respectively, P , 0.05, neonatal death 6.8, 9.5vs. 43.8, ...

Periodontal diseases affect the majority of the population either as gingivitis or periodontitis. Recently there have been many studies that link or seek to find a relationship between periodontal disease and other systemic diseases including, cardiovascular disease, diabetes, stroke, and adverse pregnancy outcomes. For adverse pregnancy outcomes, the literature is inconclusive and the magnitude of the relationship between these 2 has not been fully decided. The goal of this paper is to review the literature regarding periodontal diseases and adverse pregnancy outcomes, and provide oral health care providers with resources to educate their patients. Alternatively, this paper will also discuss what is occurring to help increase the availability of care for pregnant women and what oral health care providers can do to help improve these issues.. ...

Gender is known to influence pregnancy outcomes. Recent studies have reported an association between air pollution exposure and adverse pregnancy outcomes, but gender differences have not been considered. In order to assess the current evidence of the interactive effects between gender and air pollution on pregnancy outcomes we undertook a systematic literature review. Using a comprehensive list of keywords, English language articles published between 1966 and 2005 were retrieved from major databases. Additional information on gender was obtained from the study authors. Studies were included if they contained well-defined measurements of ambient air pollutants, investigated pregnancy outcomes and reported estimates by gender. In total 11 studies were included. The quality of the studies was assessed using the framework in Systematic Reviews in Health Care Meta-analysis in context and Brackens Guidelines. Of the 11 studies, four evaluated low birth weight (LBW); one each evaluated very low birth ...

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) established the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b) to study women for whom the current pregnancy will lead to their first delivery (nulliparas). About 40% of pregnant women in the United States are nulliparas. Because little or no information from previous pregnancy outcomes is available to guide assignment of risk or mitigating interventions, adverse pregnancy outcomes in nulliparas are especially unpredictable. The underlying mechanisms of adverse pregnancy outcomes such as preterm birth, preeclampsia, fetal growth restriction and stillbirth are interrelated and therefore will be evaluated as part of this study. The information gained will benefit women who are pregnant or who are considering pregnancy and their physicians. In addition, the knowledge will support future research aimed at improving care and health outcomes for a critical group of at-risk women who ...

Background: Smoking habit acts as the risk factor for Periodontal disease and Adverse pregnancy outcomes. Mild maternal smoking might also cause whopping adverse pregnancy outcomes. Lack of awareness in pregnant woman regarding the adverse outcome of pregnancy with maternal smoking is very common in developing countries like India. The objective of this study was to evaluate knowledge and awareness of south Indian pregnant female about maternal smoking and its association with adverse pregnancy outcomes. Materials and Methods: Multiple optioned 21 questionnaires was prepared with four categories i.e about smoking habit, stress levels, smoking effects on pregnancy outcomes, and discontinuing the habit. Maternal smoking also related with stress levels. Questionnaire forms were distributed to 440 pregnant patients who visited primary health centers in primary health care centers in several parts of south India. Answers were evaluated based on the current evidence available. Results: Most of the ...

Presently, the matter of pregnancy outcomes of patients with pregnancy related AKI (PR-AKI) were disputed. Thus, we conducted a meta-analysis to evaluate the impact of PR-AKI on pregnancy outcomes. We systematically searched MEDLINE, Embase, VIP, CNKI and Wanfang Databases for cohort or case-control studies in women with PR-AKI and those without AKI as a control group to assess the influence of PR-AKI on pregnancy outcomes and kidney outcome. Reduction of odd ratio (OR) was calculated by a random-effects model. One thousand one hundred fifty two articles were systematically reviewed, of those 11 studies were included, providing data of 845 pregnancies in 834 women with PR-AKI and 5387 pregnancies in 5334 women without AKI. In terms of maternal outcomes, women with PR-AKI had a greater likelihood of cesarean delivery (OR, 1.49; 95% confidence interval [CI], 1.37 to 1.61), hemorrhage (1.26; 1.02 to 1.56), HELLP syndrome (1.86; 1.41 to 2.46), placental abruption (3.13; 1.96 to 5.02), DIC (3.41; 2.00 to 5

There is a growing number of studies on the association between ambient air pollution and adverse pregnancy outcomes, but their results have been inconsistent. Consequently, a comprehensive review of this research area is needed. There was a wide variability in studied pregnancy outcomes, observed gestational windows of exposure, observed ambient air pollutants, applied exposure assessment methods and statistical analysis methods Gestational duration, preterm birth, (low) birth weight, and small for gestational age/intrauterine growth restriction were most commonly investigated pregnancy outcomes. Gestational windows of exposure typically included were whole pregnancy period, 1st, 2nd, 3rd trimester, first and last gestational months. Preterm birth was the outcome most extensively studied across various gestational windows, especially at the beginning and at the end of pregnancy. Particulate matter, nitrogen dioxide, ozone, and carbon monoxide were the most commonly used markers of ambient air ...

There are two main situations where screening for the management of STI in pregnancy is an option for resource poor countries. This is because there are cheap screening tests available for the diagnosis of both maternal syphilis and HIV infection.. Given the impact maternal syphilis has on pregnancy outcome, screening and treatment of syphilis in pregnant women at least once during pregnancy should be performed. In most resource poor developing countries, the RPR test is the most common screening assay. This test is cheap and simple although, like other non-treponemal tests, it is susceptible to false positive reactions from other maternal infections or autoimmune disease. These include common conditions like pregnancy, infection, measles, and malaria. Biological false positive (BFP) reactions are common in malaria endemic areas and may account for up to 30% of reactive RPR tests.6 Although the CDC recommends screening at the first ANC visit and again in the third trimester in high prevalence ...

TY - JOUR. T1 - Subsequent pregnancy outcomes in recurrent miscarriage patients with a paternal or maternal carrier of a structural chromosome rearrangement. AU - Sugiura-Ogasawara, Mayumi. AU - Aoki, Koji. AU - Fujii, Tomoyuki. AU - Fujita, Tomio. AU - Kawaguchi, Rie. AU - Maruyama, Tetsuo. AU - Ozawa, Nobuaki. AU - Sugi, Toshitaka. AU - Takeshita, Toshiyuki. AU - Saito, Shigeru. PY - 2008/7/1. Y1 - 2008/7/1. N2 - Information concerning the prognosis of subsequent pregnancies in patients with reciprocal translocations is limited. This study was performed to determine the percentage success rate with first pregnancies after ascertainment of a carrier status. A total of 2,382 couples with a history of two or more consecutive miscarriages were studied in multicenters. The prevalence of an abnormal chromosome in either partner was examined, and subsequent success rates were compared between cases with and without an abnormal karyotype in either partner. A total of 129 couples (5.4%) had an abnormal ...

The use of oocyte donation (OD) has increased continuously over the last three decades, and it is now an indispensable part of assisted reproductive technology (ART). With OD, it has become possible to overcome the biological barrier of ovarian follicle pool depletion and the general age-related decline in fertility. This review contains a thorough appraisal of the safety of OD with an analysis of short-term pregnancy outcomes. Salient up-to-date evidence was evaluated, which revealed that in comparison with both IVF with autologous oocytes, and naturally conceived pregnancies, there is: (i) an increased risk of hypertensive disorders of pregnancy and preeclampsia; (ii) an increased risk of low birth weight and preterm birth and (iii) an increased risks of obstetric emergencies, following OD treatment. As a precaution, it is therefore highly encouraged to perform only single embryo transfer (SET) and to prescribe prophylactic low-dose aspirin during OD pregnancies. ...

Background/Purpose: Actually better control of rheumatoid arthritis (RA) activity leads to new interrogations and daily questions about pregnancy. Only few studies have studied pregnancy outcomes in women with RA, and results have shown some discrepancies. The objective is to determine the effect of Rheumatoid Arthritis on pregnancy outcomes, specially hypertension and preeclampsia, low birth weight, preterm birth, perinatal mortality, congenital malformation and cesarean section in women with Rheumatoid Arthritis Methods: A litterature search was performed from Medline and Cochrane databases for articles published in english from 1955 to May 2016. Studies were eligible if they presented prevalence study, including national birth registry. Population were women with Rheumatoid Arthritis and keys terms related to pregnancy outcomes. Meta-analysis were performed to assess odds-ratios (OR) for each studied group using the inverse variance approach to estimate pooled OR with their 95% confidence ...

We assessed the effects of physical activity on pregnancy outcome in 2741 Filipino women identified during pregnancy as part of a two-year longitudinal study. Specific elements of physical activity hypothesized to be relevant to pregnancy outcome were posture, energy expenditure, and physical stress. Variables were developed for nine household and 48 formal and informal economic activities. Analyses were stratified by whether the woman performed formal waged work outside of the home, income-related activity at home, or was economically inactive. Results show that traditional definitions of physical activity and work based on participation in the formal labour force ignore a sizeable amount of home economic production, as well as the physical demands of housework. We saw no difference in risk of low birthweight or preterm delivery in economically active compared to economically inactive women. However, we found that increased amounts of standing activity affected pregnancy outcome in certain ...

TY - JOUR. T1 - Preconceptional cardiovascular health and pregnancy outcomes in women with systemic lupus erythematosus. AU - Eudy, Amanda M.. AU - Siega-Riz, Anna Maria. AU - Engel, Stephanie M.. AU - Franceschini, Nora. AU - Howard, Annie Green. AU - Clowse, Megan E.B.. AU - Petri, Michelle. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Objective. To estimate the effects of preconceptional cardiovascular (CV) health, measured by American Heart Association (AHA) guidelines, on pregnancy outcomes in women with systemic lupus erythematosus (SLE). Methods. The study included patients in the Hopkins Lupus Pregnancy Cohort. Body mass index (BMI), total cholesterol, and blood pressure (BP) in the most recent clinic visit prior to conception or first trimester were used to determine CV health (ideal, intermediate, or poor health) based on AHA definitions. Outcomes included preterm birth, gestational age at birth, and small for gestational age (SGA). Multivariable linear and logistic regression models with ...

non viable pregnancy - MedHelps non viable pregnancy Center for Information, Symptoms, Resources, Treatments and Tools for non viable pregnancy. Find non viable pregnancy information, treatments for non viable pregnancy and non viable pregnancy symptoms.

Time-to-pregnancy (TTP) has never been studied in an African setting and there are no data on the rates of adverse pregnancy outcomes in South Africa. The study objectives were to measure TTP and the rates of adverse pregnancy outcomes in South Africa, and to determine the reliability of the questionnaire tool. The study was cross-sectional and applied systematic stratified sampling to obtain a representative sample of reproductive age women for a South African population. Data on socio-demographic, work, health and reproductive variables were collected on 1121 women using a standardized questionnaire. A small number (n = 73) of randomly selected questionnaires was repeated to determine reliability of the questionnaire. Data was described using simple summary statistics while Kappa and intra-class correlation statistics were calculated for reliability. Of the 1121 women, 47 (4.2%) had never been pregnant. Mean gravidity was 2.3 while mean parity was 2.0 There were a total of 2467 pregnancies; most (87%)

Background: Exposure to alcohol and tobacco during pregnancy may lead to developmental disorders in the foetus and can also adversely impact pregnancy outcomes and the newborns health status. Objective: Assessment of alcohol consumption and tobacco use during pregnancy as well as their impact on pregnancy outcomes and birth parameters of the newborn in a selected group of mothers with children aged ≤ 2 years. Material and methods: The study was conducted in 104 mothers with children aged ≤ 2 years living in the Mazowiecki Voivodeship. A questionnaire was used for assessing selected lifestyle parameters tobacco and alcohol use, dietary supplements use, physical activity during pregnancy, socio-demographic characteristics as well as childrens birth parameters (birth weight, length, head circumference, chest circumference). Data were analyzed statistically using logistic regression analysis, Spearmans rang correlation, the Mann-Whitney U, Kruskal-Wallis, Student-t, Tukey and Chi2 tests ...

Authors: B Bello, D Kielkowski, D Heederik, K Wilson.. Source: BMC Public Health 2010, Sept 21; 10:565.. Summary:. Background: Time-to-pregnancy (TTP) has never been studied in an African setting and there are no data on the rates of adverse pregnancy outcomes in South Africa. The study objectives were to measure TTP and the rates of adverse pregnancy outcomes in South Africa, and to determine the reliability of the questionnaire tool.. Methods: The study was cross-sectional and applied systematic stratified sampling to obtain a representative sample of reproductive age women for a South African population. Data on socio-demographic, work, health and reproductive variables were collected on 1121 women using a standardized questionnaire. A small number (n = 73) of randomly selected questionnaires was repeated to determine reliability of the questionnaire. Data was described using simple summary statistics while Kappa and intra-class correlation statistics were calculated for ...

Preterm (PT) and Low birth weight (LBW) are considered to be the most relevant biological determinants of newborn infants survival, both in developed and in developing countries. Numerous risk factors for PT and LBW have been defined in the literature. Infections of the genitourinary tract infections along with various biological and genetic factors are considered to be the most common etiological factors for PT/LBW deliveries. However, evidence suggests that sub-clinical infection sites that are also distant from the genitor-urinary tract may be an important cause for PT/LBW deliveries. Maternal periodontal status has also been reported by many authors as a possible risk factor for PT and LBW, though not all of the actual data support such hypothesis. The aim of this paper is to review the evidence from various published literature on the association between the maternal periodontal status and adverse pregnancy outcomes. Although this review found a consistent association between periodontitis ...

TY - JOUR. T1 - Predictors of pregnancy outcomes in patients with lupus. T2 - A cohort study. AU - Buyon, Jill P.. AU - Kim, Mimi Y.. AU - Guerra, Marta M.. AU - Laskin, Carl A.. AU - Petri, Michelle. AU - Lockshin, Michael D.. AU - Sammaritano, Lisa. AU - Branch, D. Ware. AU - Porter, T. Flint. AU - Sawitzke, Allen. AU - Merrill, Joan T.. AU - Stephenson, Mary D.. AU - Cohn, Elisabeth. AU - Garabet, Lamya. AU - Salmon, Jane E.. N1 - Publisher Copyright: © 2015 American College of Physicians. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.. PY - 2015/8/4. Y1 - 2015/8/4. N2 - Background: Because systemic lupus erythematosus (SLE) affects women of reproductive age, pregnancy is a major concern. Objective: To identify predictors of adverse pregnancy outcomes (APOs) in patients with inactive or stable active SLE. Design: Prospective cohort. Setting: Multicenter. Patients: 385 patients (49% non-Hispanic white; 31% with prior nephritis) with SLE in the PROMISSE (Predictors of Pregnancy ...

In 2001-2008, 2.9% of pregnant North Carolina women were drivers in one or more crashes. After a single crash, compared to not being in a crash, pregnant drivers had slightly elevated rates of preterm birth and premature rupture of the membranes. Following a second or subsequent crash, pregnant drivers had more highly elevated rates of preterm birth, premature rupture of the membranes and stillbirth. Stillbirth rates were elevated following crashes involving unbelted pregnant drivers compared to belted pregnant drivers ...

New England Journal of Medicine March 30, 2017 Vol. 376 No. 13 http://www.nejm.org/toc/nejm/medical-journal Original Article Quadrivalent HPV Vaccination and the Risk of Adverse Pregnancy Outcomes Nikolai M. Scheller, M.D., Björn Pasternak, M.D., Ph.D., Ditte Mølgaard-Nielsen, M.Sc., Henrik Svanström, Ph.D., and Anders Hviid, Dr.Med.Sci. N Engl J Med 2017; 376:1223-1233 March 30, 2017 DOI: 10.1056/NEJMoa1612296 Abstract…

Background: While the relationship between hemoglobin (Hb) concentrations and pregnancy outcomes has been studied often, most reports have focused on a specific Hb cutoff used to define anemia. Fewer studies have evaluated pregnancy outcomes across the entire range of Hb values. Moreover, to date, most studies of the relationship of Hb concentrations to pregnancy outcomes have been done in high-income countries. Thus, we have sought to determine the relationship between the range of maternal Hb concentrations and adverse birth outcomes among South Asian pregnant women.Methods: For this study, we used data collected from two South Asian countries (Pakistan - Sindh Province and two sites in India - Belagavi and Nagpur) in a prospective maternal and newborn health registry study. To assess the association between Hb concentrations and various maternal and fetal outcomes, we classified the Hb concentrations into seven categories. Regression analyses adjusting for multiple potential confounders were

TY - JOUR. T1 - The epidemiology of pregnancy outcomes in rural Burkina Faso. AU - Bell, Jacqueline S.. AU - Ouedraogo, Moctar. AU - Ganaba, Rasmane. AU - Sombie, Issiaka. AU - Byass, Peter. AU - Baggaley, Rebecca F.. AU - Filippi, Veronique. AU - Fitzmaurice, Ann E.. AU - Graham, Wendy J.. PY - 2008/7. Y1 - 2008/7. N2 - Objectives To describe levels and causes of pregnancy-related mortality and selected outcomes after pregnancy (OAP) in two districts of Burkina Faso.Methods A household census was conducted in the two study districts, recording household deaths to women aged 12-49 years from 2001 to 2006. Questions on pregnancy outcomes in the last 5 years for resident women of reproductive age were included, and an additional method - direct sisterhood - was added in part of the area. Adult female deaths were followed-up with verbal autopsies (VA) with household members. A probabilistic model for interpreting VA data (InterVA-M) was used to determine distributions of probable causes of death. ...

Design - Comparative study of pregnancy outcome for parturients who had stayed in an antenatal village and for those admitted directly from the community. Setting - A rural hospital in Zimbabwe. Outcome measures - Birthweight, perinatal mortality and degree of obstetrical intervention. Results - Women who stayed in the antenatal village experienced better pregnancy outcome than women admitted directly from the community. Birthweight was greater, perinatal mortality lower, and obstetrical intervention less often required in the antenatal village group. Conclusions - Lack of randomisation, differences between the two groups in antenatal risk factors, and lack of information relating to socio-economic status suggest that generalisations beyond the specific case be made cautiously.

BACKGROUND: Malaria in pregnancy (MiP) is a major public health problem in endemic areas of sub-Saharan Africa and has important consequences on birth outcome. Because MiP is a complex phenomenon and malaria epidemiology is rapidly changing, additional evidence is still required to understand how best to control malaria. This study followed a prospective cohort of pregnant women who had access to intensive malaria screening and prompt treatment to identify factors associated with increased risk of MiP and to analyse how various characteristics of MiP affect delivery outcomes. METHODS: Between October 2006 and May 2009, 1,218 pregnant women were enrolled in a prospective cohort. After an initial assessment, they were screened weekly for malaria. At delivery, blood smears were obtained from the mother, placenta, cord and newborn. Multivariate analyses were performed to analyse the association between mothers characteristics and malaria risk, as well as between MiP and birth outcome, length and weight at

To study the effect of endometrial thickness and pattern measured using ultrasound upon pregnancy outcomes in patients undergoing IVF-ET. One thousand nine hundred thirty-three women undergoing IVF treatment participated in the study. We assessed and recorded endometrial patterns and thickness on the day of human chorionic gonadotropin (hCG) administration. Receiver operator curves (ROC) were used to determine the predictive accuracy of endometrial thickness. Cycles were divided into 3 groups depending on the thickness (group 1: ≤ 7 mm; group 2: | 7 mm to ≤ 14 mm; group 3: | 14 mm). Each group was subdivided into three groups according to the endometrial pattern as follows: pattern A (a triple-line pattern consisting of a central hyperechoic line surround by two hypoechoic layers); pattern B (an intermediate isoechogenic pattern with the same reflectivity as the surrounding myometrium and a poorly defined central echogenic line); and pattern C (homogenous, hyperechogenic endometrium). Clinical

Many studies have been conducted to examine whether Caesarean Section (CS) or vaginal birth (VB) was optimal for better maternal and neonatal outcomes in preterm births. However, findings remain unclear. Therefore, this secondary analysis of World Health Organization Global Survey (GS) and Multi-country Survey (MCS) databases was conducted to investigate outcomes of preterm birth by mode of delivery. Our sample were women with singleton neonates (15,471 of 237 facilities from 21 countries in GS; and 15,053 of 239 facilities from 21 countries in MCS) delivered between 22 and |37 weeks of gestation. We assessed association between mode of delivery and pregnancy outcomes in singleton preterm births by multilevel logistic regression adjusted for hierarchical data. The prevalences of women with preterm birth delivered by CS were 31.0% and 36.7% in GS and MCS, respectively. Compared with VB, CS was associated with significantly increased odds of maternal intensive care unit admission, maternal near miss, and

Sponsor. National Institutes of Health (NIH). Principal Investigator. Dr. Hazel Nichols, Epidemiology. Project Run Dates. 7/01/2017 to 6/30/2022. Summary. In the U.S., more than 45,000 women are diagnosed with cancer during adolescence and young adulthood (AYA, ages 15-39 at diagnosis) each year. Fertility and reproductive outcomes are critical issues for AYA cancer survivors but little is known about the effect of diagnosis and treatment on the clinical course and outcome of future pregnancy. Our study will leverage existing data sources to assess clinical pregnancy outcomes among women with the most common AYA cancers (lymphoma, breast, melanoma, thyroid and gynecologic cancer) that account for ,70% of all diagnoses. Our findings will provide urgently needed answers that can be directly applied to fertility preservation, preconception, and prenatal counseling.. Data for this study come from the Kaiser Permanente (KP) Northern and Southern California integrated healthcare systems and from an ...

Results: Of 364,363 singleton pregnancies resulting in live or stillbirths 1,969 (0.5%) were in women with IBD. Women with CD were more likely to have pre-term births (OR=1.42 95%CI;1.12-1.79), babies with low birth weights (OR=1.39;1.05-1.83) and postpartum haemorrhage (OR=1.27;1.04-1.55) whereas women with UC were only at increased risk of pre-term births with an absolute risk difference of ,2.7%. These risks remained independent of caesarean section (CS). Prior surgery for IBD did not increase risk of adverse birth outcomes or pregnancy related complications compared to cases without surgery, however women with IBD were more likely to have an elective CS ...

There has been limited research addressing whether behavioural change in relation to smoking is maintained throughout pregnancy and the effect on perinatal outcomes. A cohort study addressed lifestyle behaviours of 907 women who booked for antenatal care and delivered in a large urban teaching hospital in 2010-2011. Adverse perinatal outcomes were compared for

Maternal anthropometry and pregnancy outcomes: a WHO collaborative study , Maternal anthropometry and pregnancy outcomes: a WHO collaborative study , کتابخانه دیجیتال دانشگاه علوم پزشکی اصفهان

Some, but not all, studies have shown an association between in utero exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants and adverse pregnancy outcomes, including preterm delivery, low birth weight, and lower Apgar scores. One of the difficulties in estimating the risk for adverse outcomes in this population is that studies have used varying methodologies and have relied on different means of identifying and classifying neonatal outcomes. Furthermore, many of these studies have not taken into consideration other variables that may affect neonatal outcomes, including the use of other medications, smoking, and maternal mental illness. We often question whether depression itself (as opposed to the antidepressants used to treat it) may contribute to adverse outcomes. This question stems from early research conducted by Steer and colleagues (!992) and Orr and Miller (1995). Steer observed that the risk of a poor pregnancy outcome rose by 5-7% for each point increase on the Beck ...

The Adverse Pregnancy Outcomes Reporting System records adverse pregnancy outcomes in infants with congenital anomalies (birth defects) and other serious neonatal conditions. This report describes the county-specific prevalence rates of seven groups of major birth defects, a listing of the disease codes and a brief description of each defect and similar information about other adverse pregnancy outcomes ...

Impaired fetal growth and preterm birth are the leading causes of neonatal and infant mortality worldwide and there is a growing scientific literature suggesting that environmental exposures during pregnancy may play a causal role in these outcomes. Our purpose was to assess the environmental exposure of the Fetal Growth Longitudinal Study (FGLS) participants in the multinational INTERGROWTH-21(st) Project. First, we developed a tool that could be used internationally to screen pregnant women for such exposures and administered it in eight countries on a subsample (n = 987) of the FGLS participants. The FGLS is a study of fetal growth among healthy pregnant women living in relatively affluent areas, at low risk of adverse pregnancy outcomes and environmental exposures. We confirmed that most women were not exposed to major environmental hazards that could affect pregnancy outcomes according to the protocols entry criteria. However, the instrument was able to identify some women that reported various

The obstetrical and gynecological manifestation of Crohns disease is particularly challenging for young women and demands special attention, according to an article in the International Journal of Womens Health. Pregnant women with CD are considered high-risk patients due to associated complications. Some of the prevalent complications are premature birth, low birth weight, and congenital anomalies. To minimize the risk for adverse pregnancy/birth outcomes, it is recommended that remission of CD symptoms be achieved before conception. Treatment of CD in pregnant women is similar to that among the nonpregnant population, and there is no valid reason to terminate it, since most of the drugs are proven to be safe. Women with CD who wish to conceive or are already pregnant need to be properly advised according to the newest guidelines on the subject, given by the European Crohns and Colitis Organization. Gynecological manifestations are another special feature of CD. They are important in that ...

Maternal supraphysiological estradiol (E2) environment during pregnancy leads to adverse perinatal outcomes. However, the influence of oocyte exposure to high E2 levels on perinatal outcomes remains unknown. Thus, a retrospective cohort study was conducted to explore the effect of high E2 level induced by controlled ovarian stimulation (COH) on further outcomes after frozen embryo transfer (FET). The study included all FET cycles (n = 10,581) between 2014 and 2017. All cycles were categorized into three groups according to the E2 level on the day of the human Chorionic Gonadotropin trigger. Odds ratios (ORs) and their confidence intervals (CIs) were calculated to evaluate the association between E2 level during COH and pregnancy outcomes and subsequent neonatal outcomes. From our findings, higher E2 level was associated with lower percentage of chemical pregnancy, clinical pregnancy, ongoing pregnancy, and live birth as well as increased frequency of early miscarriage. Preterm births were more ...

This is the most comprehensive cohort study of prepregnancy care in women with type 1 diabetes in the U.K., describing glycemic control throughout pregnancy and multiple pregnancy outcomes. In addition, we have complete follow-up on a large and recent unselected clinic population, a collection of monthly A1C measurements from a single laboratory, and careful assessment of potential confounding factors. The prepregnancy clinic was attended by 38% of women, which is in keeping with findings from the CEMACH report (1). There was a significant increase in numbers of women receiving prepregnancy care during the study. This figure is lower than that of 58% reported in a recent study from Denmark (22). In that study, preconception guidance was not defined, and only 34% women were monitoring their blood glucose at the time of conception compared with 100% women in our study. This might suggest that the preconception guidance had been limited compared with prepregnancy care in our study.. Our study shows ...

Pregnancy Outcomes in US Prisons, 2016-2017 Carolyn Sufrin MD, PhD, Lauren Beal MPH, Jennifer Clarke MD, MPH, Rachel Jones PhD, and William D. Mosher PhD Published online: March 21, 2019 Objectives. To collect national data on pregnancy frequencies and outcomes among women in US state and federal prisons.

BACKGROUND: The prevalence of obesity amongst women bearing children in Australia is rising and has important implications for obstetric care. The aim of this study was to assess the prevalence and impact of mothers being overweight and obese in early to mid-pregnancy on maternal, peripartum and neonatal outcomes.. METHODS: A secondary analysis was performed on data collected from nulliparous women with a singleton pregnancy enrolled in the Australian Collaborative Trial of Supplements with antioxidants Vitamin C and Vitamin E to pregnant women for the prevention of pre-eclampsia (ACTS). Women were categorized into three groups according to their body mass index (BMI): normal (BMI 18.5-24.9 kg/m2); overweight (BMI 25-29.9 kg/m2) and; obese (BMI 30-34.9 kg/m2). Obstetric and perinatal outcomes were compared by univariate and multivariate analyses.. RESULTS: Of the 1661 women included, 43% were overweight or obese. Obese women were at increased risk of pre-eclampsia (relative risk (RR) 2.99 [95% ...

The association between fluoroquinolones and arthropathy, although observed in immature animals and rarely reported in humans, has resulted in the restricted use of fluoroquinolones during pregnancy. Data from recent reports suggest that quinolone administration to children and adolescents with cystic fibrosis is safe on the basis of both clinical and magnetic resonance imaging assessments (4). However, since these observations have focused on children and adolescents, it is unclear whether in utero exposure to quinolones and their potential deposition in fetal cartilage are associated with any long-term musculoskeletal dysfunctions. Our data, which we obtained using the Denver Developmental Scale, suggest that in utero exposure to quinolones is not associated with clinically significant major musculoskeletal dysfunctions. This tool is very limited in evaluating subtle joint changes that would have been detected only by sensitive methods. Magnetic resonance imaging of weight-bearing joints of ...

During pregnancy, CKD increases both maternal and fetal risk. Adverse maternal outcomes include progression of underlying renal dysfunction, worsening of urine protein, and hypertension, whereas adverse fetal outcomes include fetal loss, intrauterine growth restriction, and preterm delivery. As such, pregnancy in young women with CKD is anxiety provoking for both the patient and the clinician providing care, and because the heterogeneous group of glomerular diseases often affects young women, this is an area of heightened concern. In this invited review, we discuss pregnancy outcomes in young women with glomerular diseases. We have performed a systematic review in attempt to better understand these outcomes among young women with primary GN, we review the studies of pregnancy outcomes in lupus nephritis, and finally, we provide a potential construct for management. Although it is safe to say that the vast majority of young women with glomerular disease will have a live birth, the counseling that we can

The risk of preeclampsia and different pregnancy problems may be higher for expectant moms whove a historical past of acute kidney injury, a brand new research finds, even when kidney perform is regular previous to pregnancy.

Study objective-To examine the effect of socioeconomic status on pregnancy outcome in an urbanised area in a rapidly developing country. Methods-A cohort of 1797 pregnant women who attended antenatal care clinics at the two 700 bed hospitals in Hatyai city was recruited from September 1994 to November 1995. The pregnant women were followed up...

Treatment of gestational diabetes reduces serious perinatal morbidity and may also improve the womans health-related quality of life.

Study Question: To what degree do records registered in the Netherlands Perinatal Registry (PRN) agree with self-report in a Study Question: naire on pregnancy outcomes in childhood cancer survivors (CCSs)? Summary Answer: This study suggests that self-reported pregnancy outcomes of CCSs agree well with registry data and that outcomes reported by CCSs agree better with registry data than do those of controls. What is Known Already: Many studies have shown that childhood cancer treatment may affect fertility outcomes in female CCSs; however, these conclusions were often based on questionnaire data, and it remains unclear whether self-report agrees well with more objective sources of information. Study Design , Size, Duration In an nationwide cohort study on fertility (inclusion period January 2008 and April 2011, trial number: NTR2922), 1420 CCSs and 354 sibling controls were invited to complete a questionnaire regarding socio-demographic characteristics and reproductive history. In total, 879 ...

Many patients with IBDs such as Crohns disease and ulcerative colitis require immunosuppressive biologic therapies to control disease activity, which is important in women because active IBD has been associated with adverse pregnancy outcomes. Multiple retrospective studies have found no association between treatment of pregnant women with IBD using biologic agents such as antagnoists of tumor necrosis factor (anti-TNF) and adverse pregnancy outcomes.. However, some of these drugs can cross the placenta; anti-TNF agents such as adalimumab or infliximab can be detected in infants until 12 months of age. In contrast, certolizumab pegol, which is a polyethylene glycolylated FaB immunoglobulin, does not bind to the neonatal Fcγ receptor that mediates transplacental transfer and was not found in infant or cord blood.. There are limited data on the long-term effects of this exposure on the development of the neonatal immune system.. Dawn B. Beaulieu et al performed a large, prospective study to ...

Results 28 pregnancies in 20 women (26±6 years old) with PAH-CHD were managed during this period. There were 18 complete pregnancies (≥20 weeks gestation (WG)), 8 abortions and 2 miscarriages. Six (33%, 95% CI (11.9 to 54.3)) patients experienced severe cardiac events. The concerned women had lower resting oxygen saturation (79.6±4.1% vs 89.3±3.8%, p,0.01). The most common cardiac complications during the complete pregnancies were heart failure (n=4) and severe hypoxaemia (n=5). Heart failure was overall severe, requiring inotropic treatment in three patients, mechanical circulatory support in one and led to one maternal death (mortality=5.0% 95% CI (0.1 to 24.9)). Obstetrical complications occurred in 25% of pregnancies. Small for gestational age was diagnosed in 39% (7/18) of fetuses. 12/18 (67%) pregnancies were delivered by caesarean section, of which 10 in emergency for obstetrical reason. Prematurity was frequent (78%), but no neonatal death occurred. ...