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Article Characteristics of colloidal copper particles prepared by using polyvinyl pyrrolidone and polyethylene glycol in chemical reduction method. A simple chemical reduction method is used to prepare colloidal copper nanoparticles where polyethylen...
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Transdermal delivery of ondansetron hydrochloride (OdHCl) can prevent the problems encountered with oral ondansetron. In previously conducted studies, effect of amount of polyvinyl pyrrolidone, permeation enhancer and casting solvent on the physicochemical properties on OdHCl were investigated. It is feasible to develop ondansetron transdermal patch by using ethyl cellulose and polyvinyl pyrrolidone with dibutyl pthalate as plasticizer, however, the desired flux is not achieved. The primary aim of this study is to use dimethyl succinate (DMS) and propylene glycol that are not incorporated in previous studies to determine their effect on the physicochemical properties of an OdHCl transdermal patch using ethyl cellulose and polyvinyl pyrrolidone. This study also investigates the effect of permeation enhancer (eugenol and phosphatidylcholine) on the release of OdHCl. The results showed that propylene glycol is a more suitable plasticizer compared to DMS in the fabrication of OdHCl transdermal patch ...
TY - JOUR. T1 - An analysis of the mechanism of cessation of uptake of macro‐molecular substances by the intestine of the young rat (closure). AU - Clarke, Rufus M.. AU - Hardy, R. N.. PY - 1969/9/1. Y1 - 1969/9/1. N2 - 1. The longitudinal distribution of cells capable of absorbing macro‐molecular material has been determined in the small intestine of the young rat by measurements of the uptake of [125I]polyvinyl pyrrolidone (PVP). 2. PVP uptake was never seen in the duodenum and became restricted to the distal half of the small intestine by the 18th day of life. The subsequent decline to zero in PVP uptake was due to an almost uniform decrease in PVP uptake by the distal half of the small intestine. 3. Histological studies indicate that this rapid decline in PVP uptake did not reflect a decrease in uptake by individual cells, but rather their replacement by new cells incapable of taking up PVP. 4. Autoradiographic estimates of turnover time in the intestinal epithelium using tritiated ...
HIGHLY LOADED AMORPHOUS EFAVIRENZ COMPOSITION AND PROCESS FOR PREPARING THE SAME - A stable and high loading ternary solid dispersion composition comprising (a) about 50% wt. to about 90% wt. of amorphous Efavirenz; (b) about 10% wt. to about 50% wt. of polyvinyl pyrrolidone (PVP), a first polymer; (c) about 1% wt. to about 30% wt. of a water-soluble second polymer; and (d) optionally about 0.1% wt. to about 50% wt. of at least one pharmaceutically acceptable excipient. Also discloses a high loading ternary composition comprising (a) a solid dispersion composition comprising (i) about 50% wt. to about 90% wt. of amorphous Efavirenz; (ii) about 10% wt. to about 50% wt. of polyvinyl pyrrolidone, a first polymer; (b) about 1% wt. to about 30% wt. of a water-soluble second polymer blended with solid dispersion of composition of (a); and (c) optionally about 0.1% wt. to about 50% wt. of at least one pharmaceutically acceptable excipient. Additionally discloses a method for preparing solid dosage ...
Polyvinylpyrrolidone definition, a white, amorphous, water-soluble powder, (C 6 H 9 NO) n , used chiefly as a vehicle in the manufacture of pharmaceuticals. See more.
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight ratios of CLA: SLS: PVP were ground in a dry process by planetary ball mill using different grinding ball size. Following the dissolution rate study, physical properties of the best dissolved co-ground formulation was studied. The accelerated stability studies were also conducted on the co-ground formulation. The results revealed that the dissolution rate of ternary ground mixtures was much higher than that of the intact drug (p | 0.001). Decreasing the grinding ball size and weight with the same rotation speed resulted in particles with decreased dissolution. On the other hand, increasing the PVP concentration in
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Polyvinylpyrrolidone K-30 Page Number: 3 Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading. read more ...
Suitable disintegrants include lightly crosslinked polyvinyl pyrrolidone, corn starch, potato starch, maize starch, and modified starches, croscarmellose sodium, cross-povidone, sodium starch glycolate, and mixtures thereof. You need to confirm dry mouth symptoms that reported for intravitreal or severly dry to prevent. To avoid the spread of infection, do not use the inhaler for more than one person. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. New Users: Please register, then proceed to purchase the article. Art and Images in Psychiatry.. If concomitant drug use is unavoidable, frequently monitor serum electrolytes and replace as necessary and electrocardiograms. Nasal Spray at regular intervals since its effectiveness depends on its regular use. The compositions can be formulated in any way as described below and as known to those of skill in the art. The present invention is also directed to methods of treatment ...
By Loraine, Gregory A ABSTRACT: In this paper, components of an industrial wastewater that cause operational problems during biological treatment were oxidized by UV light and hydrogen peroxide (UV/H^sub 2^O^sub 2^). Preoxidation of wastewater was shown to remove polyvinylpyrrolidone (PVP) and ethoxylate surfactant and increase overall biodegradability. Several UV intensities and hydrogen peroxide concentrations were tested to find optimal conditions for the complete depolymerization of PVP in a synthetic wastewater composed of high concentrations of hydroxyl radical scavengers. To compare treatment options, absorption isotherms for PVP on granular activated carbon (GAC) in water and in the synthetic phase- inversion wastewater matrix were determined. The data were extrapolated to estimate the cost of using UV/H^sub 2^O^sub 2^, GAC, or off-site treatment. It was found that UV/H^sub 2^O^sub 2^ pretreatment was economically viable. Incomplete oxidation of an ethoxylate surfactant increased foaming ...
Severn Biotech, Limited Poly-vinyl Pyrollidone (PVP) MW 40,000 - Polyvinylpyrrolidone PVP (1-ethenylpyrrolidin-2-one) Molecular biology techniques it is used in Hybridisation procedures in the detection of DNA or RNA. Polyvinylpyrrolidone (PVP), also commonly called Polyvidone or Povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP is soluble in water and other polar solvents. When dry it is a light flake hygroscopic powder, readily absorbing up
Flat-bottomed polystyrene microtitre plate (Nunc, New York, USA) was coated with 200 µl of leaf extracts prepared in carbonate buffer containing 2 % polyvinyl pyrrolidone (PVP) and incubated overnight at 4 °C. The coated plates were washed thrice with PBST (PBS containing 0.05% (v/v) Tween-20, pH 7.4) and blocked with 200 µl of 1% bovine serum albumin (BSA) in PBS (at 37 °C) for 1 h. After three washes, 200 µl of polyclonal antiserum diluted with 1% BSA in PBST (1:1000) was added to each well of the plate; then, the plate was incubated for 2 h at 37 °C. Plate was washed thrice and 200 µl of alkaline phosphatase-conjugated secondary goat anti-rabbit antibody (Sigma Aldrich, St. Louis, USA) diluted in antibody dilution buffer (2% PVP and 0.2% BSA in PBS-T) (1:30,000) was added to each well of the plate, and the plate was then incubated at 37 °C for 2 h. The plate was washed three times, and then 200 µl of the 1 mg/ml pNPP-Na (Sigma, Aldrich, St. Louis, USA) in substrate buffer (10% ...
The well-known AuAg nanohybrid system was effectively synthesized, utilizing polyvinyl pyrrolidone (PVP) as a multiple metal precursor reducing agent (based solely on their reduction potentials), thereby drastically decreasing their activation energy of diffusion and readily facilitating the homogenous alloy
Corneal staining type was graded in a 5-point scale over the 5 corneal regions by Investigator using a slit lamp; 0=none, 1=trace, 2=mild, 3=moderate, and 4=severe. Maximum grade of corneal staining type over the 5 corneal regions was categorized either absence or presence of corneal staining for the analysis ...
The object of this invention is to provide a process for producing a solid dispersion, which has overcome the disadvantages of the conventional production technology for solid dispersions, The invention comprises employing a twin-screw extruder in the production of a solid dispersion. In accordance with the invention, a solid dispersion can be expediently produced without heating a drug and a polymer to or beyond their melting points and without using an organic solvent for dissolving both components and the resulting solid dispersion has excellent performance characteristics.
Sigma-Aldrich offers abstracts and full-text articles by [Zehadin Gashi, Roberta Censi, Ledjan Malaj, Roberto Gobetto, Matteo Mozzicafreddo, Mauro Angeletti, Admir Masic, Piera Di Martino].
The global superdisintegrants market size was valued at around USD 258.6 million in 2016 and is expected to grow at a CAGR of 7.2% over the forecast period
VIVAPHARM® PVP K30 is the classic wet binder with optimal balance between adhesive strength and ease of handling. It has excellent solubility in water and a range of organic solvents, and is supplied as a free-flowing powder with spherical particle morphology. This ensures rapid dispersibility and ultimate flexibility in the solvent of choice.
* Polyvinylpyrrolidone: on the market for 70 years now, , * Even more patient safety for customers in the pharmaceutical industry, , , , Ludwigshafen, Germany - A new plastic film, for which a...
Hi all, I stumbled across a reference for this problem. It is: Kruk, P.A. and Auersperg, N. Percoll Centrifugation Eliminates Mold Contaminants from Cell Cultures. In Vitro Cell. Dev. Biol. 27A p 273 (1991). Good luck! Michelle Gleeson Molecular Parasitology Unit University of Technology, Sydney AUSTRALIA michelle.gleeson at uts.edu.au ...
A mixture of estradiol or other estrogen and an uncrosslinked, water-insoluble vinylpyrrolidone copolymer provides a matrix which gradually releases the medicament upon application to the skin of a patient in the form of an ointment, gel or film. The polymer provides for the slow and sustained release of the medicament upon topical application to the skin so that the concentration of drug in the blood plasma of the patient is maintained within the levels required for clinical efficacy.
From: zhuwenhui ,[email protected], To: [email protected] Cc: zhuwenhui ,[email protected], Subject: [dts] [PATCH V1 14/17] tests/pvp_vhost_user_reconnect:vhost-net changed to absolute path Date: Thu, 29 Aug 2019 16:03:53 +0800 Message-ID: ,[email protected], (raw) In-Reply-To: ,[email protected], Vhost-net changed to absolute path Signed-off-by: zhuwenhui ,[email protected], --- tests/TestSuite_pvp_vhost_user_reconnect.py , 9 +++++---- 1 file changed, 5 insertions(+), 4 deletions(-) diff --git a/tests/TestSuite_pvp_vhost_user_reconnect.py b/tests/TestSuite_pvp_vhost_user_reconnect.py index 69c4bed..c5c7b96 100644 --- a/tests/TestSuite_pvp_vhost_user_reconnect.py +++ b/tests/TestSuite_pvp_vhost_user_reconnect.py @@ -83,6 +83,7 @@ class TestPVPVhostUserReconnect(TestCase): self.tester.send_expect(mkdir -p %s % self.out_path, # ) # create an instance to set stream field setting self.pktgen_helper = ...
Every time someone puts up a post on improving PVP most of the replies are: No PVP, DDO isnt balanced for PVP, go play WoW... etc. Many of these claims hold true. In most E-SPORTS, team PvP games include set in strategy and leveling curves. The players that start out weak,end up very strong in end game (carries). The ones that start out strong at the start end up weaker in endgame. The high dps players have low durability. And the high durability players have low dps. The Dungeons
an essential structural component of living cells and source of energy for animals; includes simple sugars with small molecules as well as macromolecular substances; are classified according to the number of monosaccharide groups they contain. ...
With 5.2 coming out tomorrow, I was wondering anyone has anything to say about going MM for PVP. With all the self healing and damg increase will be closer to BM? Im also looking for a Build and stats that would be the best focusing on. Currently Im focusing on: PVP Rezil | Agi | PVP Power | Crit | Haste | Mast
Im sorry this may be a stupid question but I was just curious about grouping in PVP. When we Enter the Mists to do PVP, is there an option to bring your group with you? Or does each person have to join it separately. If so, is the whole server based in the same instance of The Mists. Like if Im questing somewhere different than my friend and we both are talking over Skype and decide to do some pvp, do we have to group first and then join The Mist or can we both just join it and
This may open the possibility of players taking tier sets to take advantage of superior set bonuses. This would be particularly attractive to RBG FCs, as PVP power isnt important to them, resilience wont be on gear anymore, and no PVP sets are tailored for flag carriers ...
Is there away to remove counting Unguilded for "Guild that has suffered the most at our hands" & "Guild that has killed us the most" on the PVP stats box on the roster index page? Having it be that we have lost / won against unguilded individuals the most makes that particular stat meaningless ...
The best rotations and effective strategies for Destruction Warlocks in Arena PvP. This guide also discusses common mistakes that Destruction Warlocks make.
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And Many More…. After the basic information, the Global Sodium Starch Glycolate Industry report sheds light on the production, production plants, their capacities, global production and revenue are studied. Also, the Global Sodium Starch Glycolate growth in various regions and R&D status are also covered.. Further in the report, Global Sodium Starch Glycolate is examined for price, cost and gross revenue. These three points are analysed for types, companies and regions. In prolongation with this data sale price for various types, applications and region is also included. The Global Sodium Starch Glycolate Industry consumption for major regions is given.. Additionally, type wise and application wise consumption figures are also given.. Global Sodium Starch Glycolate Market Split by applications, this report focuses on sales, market share and growth rate of Global Sodium Starch Glycolate in each application, can be divided into:. ...
Looking for online definition of polyvinylpyrrolidone in the Medical Dictionary? polyvinylpyrrolidone explanation free. What is polyvinylpyrrolidone? Meaning of polyvinylpyrrolidone medical term. What does polyvinylpyrrolidone mean?
A novel nifedipine-containing solid pharmaceutical preparation composition comprising a mixture of nifedipine and at least one 1st(a) substance selected from polyvinyl pyrrolidone, methyl cellulose, hydroxypropyl cellulose and hydroxypropylmethyl cellulose; a mixture of nifedipine, at least one 1st(b) substance selected from polyvinyl pyrrolidone, urea, citric acid mannitol, succinic acid, methyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose and amino acid, and at least one 2nd substance selected from a surface active agent, polyethylene glycol, propylene glycol, glycerol, a glycerol fatty acid ester and a vegetable oil; or a mixture of nifedipine, the 1st(b) substance, the 2nd substance and calcium lactate. The composition of this invention can increase the bioavailability of nifedipine and makes it possible to provide a nifedipine-containing pharmaceutical preparation which has small bulk and can be easily administered.
A man, aged 67, has been treated in 1968 by X-rays for a basal-cell carcinoma of the back. The treatment was followed by an ulcerative radiodermatitis. 3 years later, the patient was treated by ten intramuscular injections of procaine-polyvinylpyrrolidone (or procaine-povidone) for sciatic neuralgia. An orange infiltration appeared progressively around the radiodermatitis. The area was excised in 1979 and polyvinylpyrrolidone (povidone) storage, responsible for the ring-shaped orange hue, could be demonstrated in the dermis and subcutaneous fat. Special stainings confirmed the presumed chemical nature of the deposits. 3 cases of povidone pseudotumours following procaine-povidone injections had been described previously. The preferential deposit of povidone in RX-damaged skin is discussed. ...
Sodium starch glycolate is a white powder that doesnt really smell or taste like anything. It can be made from a number of different starchy foods,...
In this report, our team research the Europe Sodium Starch Glycolate market by type, application, region and manufacturer 2013-2018 and forcast 2019-2024. For the region, type and application, the sales, revenue and their market share, growth rate are key research objects; we can research the manufa
The present study was aimed to formulate the solid dispersion incorporated microcapsule to improve the dissolution rate and half life of pioglitazone hydrochloride. The solvent evaporation method was used to formulate the solid dispersion resulted increased dissolution rate, bioavailability and stability. Finally increase the half life of the drug by employ the orifice ionic gelation method to formulate solid dispersion incorporated muco-adhesive microcapsule. The solubility of pioglitazone hydrochloride was increase by the preparation of its solid dispersion with polyvinyl pyrrolidone K30 using solvent evaporation methods. The microcapsules of pioglitazone hydrochloride were prepared by (orifice ionic gelation method) employing sodium alginate as a cell forming polymer and using a different bio-adhesive polymers as carbopol, HPMC and sodium CMC in a various ratios of 1:1, 3:1, 6:1 & 9:1, by orifice ion gelation method. FT-IR spectra revealed no chemical incompatibility between drug and polymers. Drug
Global Polyvinylpyrrolidone Sales Market Report 2017 is a market research report available at US $4000 for a Single User PDF License from RnR Market Research Reports Library.
Epigallocatechin gallate (EGCG) has been recognized as the most prominent green tea extract due to its healthy influences. The high instability and low bioavailability, however, strongly limit its utilization in food and drug industries. This work, for the first time, develops amorphous solid dispersion of EGCG to enhance its bioavailability and physical stability. Four commonly used polymeric excipients are found to be compatible with EGCG in water-dioxane mixtures via a stepwise mixing method aided by vigorous mechanical interference. The dispersions are successfully generated by lyophilization. The physical stability of the dispersions is significantly improved compared to pure amorphous EGCG in stress condition (elevated temperature and relative humidity) and simulated gastrointestinal tract environment. From the drug release tests, one of the dispersions, EGCG-Soluplus® 50:50 (w/w) shows a dissolution profile that only 50% EGCG is released in the first 20 min, and the remains are slowly released
0028] The preferred embodiment of the organic vehicle consists of about 1-10 wt. % polyvinyl pyrrolidone (PVP) as the organic binder, preferably with molecular weight from 5000 to 5000000 Dalton, about 1-10 wt. % surfactant, about 50-70 wt. % organic solvent. The organic vehicle may include about 1-10 wt. % ethyl cellulose as an additional binder. All weight percents are expressed in weight percent of organic vehicle. The inclusion of PVP enhances the pastes ability to be dispersed uniformly, and it is highly compatible with silver particles. According to another preferred embedment, the surfactant can be any of the following: hydroxyfunctional carboxylic acid ester with pigment affinic groups (including, but not limited to, DISPERBYK®-108, manufactured by BYK USA, Inc.), acrylate copolymer with pigment affinic groups (including, but not limited to, DISPERBYK®-116, manufactured by BYK USA, Inc.), modified polyether with pigment affinic groups (including, but not limited to, TEGO® DISPERS ...
In this study, Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were prepared by non-solvent induced phase separation (NIPS) with compound addtive. The compound additive was made with polyvinyl pyrrolidone (PVP) and Poly ethylene glycol (PEG). The results showed that the modified PVDF membrane had better separation performance than virgin PVDF membrane. The UF flux of modified PVDF membrane can reach 684 L·h−1·m−2 and lysozyme (LZM) passage is 72.6% while virgin PVDF membrane is 313 L·h−1·m−2 and 53.2%. At the same time, the biocompatibility of PVDF membranes was also improved. Compared with commercial polysulfone hemodialysis membrane (Fresenius F60S membrane), the modified PVDF membrane had better mechanical and separation performance. The stress and tensile elongation of modified PVDF membrane was 0.94 MPa and 352% while Fresenius F60S membrane was 0.79 MPa and 59%. The LZM passage reached 72.6% while Fresenius F60S membrane was 54.4%. It was proven that the modified
Functional agglomerated speckles, for incorporation in dentifrices, include agglomerates of a water insoluble powdered functional material and a mixture of a water insoluble, ethanol soluble ethyl cellulose binder and a suitable water soluble binder, such as polyvinyl pyrrolidone. Such speckles, while more soluble or disintegrable in a flavored dentifrice than those based on ethyl cellulose binders without PVP, still can satisfactorily maintain their integrity and identity during processing of the dentifrice after addition of the speckles to the main dentifrice body, but on storage, after packaging of the dentifrice in dispensing tubes, they will soften sufficiently so as then to be essentially impalpable to one utilizing the dentifrice in brushing his teeth. Despite such softening the speckles continue to maintain their identity as separate small bodies in the dentifrice. The invented speckles are especially useful in translucent or transparent gel dentifrices, which contain components, such as
A coating is provided for a substrate comprising a polyisocyanate; an amine donor and/or hydroxyl donor; an isocyanatosilane adduct having terminal isocyanate groups and at least one hydrolyzable alkoxy group bonded to silicon; and optionally a polymer selected from the group consisting of polyethylene oxide, polyvinyl pyrrolidone, polyvinyl alcohol, polyethylene glycol, and polyacrylic acid. The coating can accommodate a drug so that when the coating is applied to a medical device, the medical device becomes drug-releasing when in contact with aqueous body fluid. A coated article as well as a method for preparing the coating is also provided.
From Preservation and Care of Philatelic Materials: The Pritt stick has a fruity odor. This odor, the alkaline nature of the product, and a spectral band of 1550 cm -1 suggest the presence of a non-volatile amine or amide. IF spectral analyses show that the glue sticks are predominantly polyvinyl pyrrolidone with some polyvinyl alcohol components that are quite stable. Glue stick adhesive is water soluble. [pottedstu, Nov 22 2001, last modified Oct 04 2004 ...
One-dimensional iridium and iridium oxide fibers were prepared by electrospinning of polyvinyl pyrrolidone ethanol solution which contained iridium(III) acetylacetonate as iridium precursor. The Ir precursors/polymer composite fibers were subsequently thermally annealed at 500 degrees C in air for 4 hours to remove the organic parts and leave IrO2 fibers. Metallic iridium fibers were obtained by reducing the IrO2 fibers with hydrogen. Also tubes by fiber templates-process is used to demonstrate how metallic Ir, IrO2 and Pt nanotubes can be produced by combining atomic layer deposition and electrospinning.. ...
Polymeric films of indomethacin were formulated employing ethyl cellulose and polyvinyl pyrrolidone as film formers and evaluated for transdermal admi..
Thermal processing of amorphous solid dispersions continues to gain interest in the pharmaceutical industry, as evident by several recently approved commercial products. Still, a number of pharmaceutical polymer carriers exhibit thermal or viscoelastic limitations in thermal processing, especially at smaller scales. Additionally, active pharmaceutical ingredients with high melting points and /or that are thermally labile present their own specific challenges. A number of formulation and process driven strategies to enable thermal processing of challenging compositions have been adopted including the use of traditional plasticizers and surfactants, temporary plasticizers utilizing sub- or supercritical carbon dioxide, designer polymers tailored for hot melt extrusion processing, and KinetiSol® Dispersing technology. The objective of the first study was to compare and contrast two thermal processing methods, HME and KinetiSol® Dispersing (KSD), and investigate the influence of polymer type, ...
Polyvinylpyrrolidone (PVP) Lyophilized is a sterile powder to prepare custom PVP concentrations for sperm micromanipulation in ICSI procedures. Contact Irvine Scientific for further product details.