INTRODUCTION: Patients on intravenous heparin require regular activated partial thromboplastin time monitoring. Laboratory-based activated partial thromboplastin time assays necessitate a delay between blood sampling and dose adjustment. Point-of-care testing could permit immediate dose adjustments, potentially enabling tighter control of anticoagulation. AIM: To assess equivalence of activated partial thromboplastin time measured by conventional laboratory assay and by a novel proprietary point-of-care testing system (Hemochron Response, ITC, Thoratec Corporation, Edison, NJ) among surgical ward patients on intravenous heparin. METHODS: A total of 39 blood samples from patients on intravenous heparin were tested with both laboratory and point-of-care assays. Assay equivalence was assessed by Bland-Altman analysis. Results. Point-of-care measurements exceeded laboratory activated partial thromboplastin time by a mean of 15 seconds (standard deviation 19). In 19 cases (49%), the point-of-care measurement
TY - JOUR. T1 - Ultrasound in the diagnosis and management of pleural effusions. AU - Soni, Nilam J.. AU - Franco, Ricardo. AU - Velez, Maria I.. AU - Schnobrich, Daniel. AU - Dancel, Ria. AU - Restrepo, Marcos I.. AU - Mayo, Paul H.. N1 - Publisher Copyright: © 2015 Society of Hospital Medicine.. PY - 2015/12/1. Y1 - 2015/12/1. N2 - We review the literature on the use of point-of-care ultrasound to evaluate and manage pleural effusions. Point-of-care ultrasound is more sensitive than physical exam and chest radiography to detect pleural effusions, and avoids many negative aspects of computerized tomography. Additionally, point-of-care ultrasound can assess pleural fluid volume and character, revealing possible underlying pathologies and guiding management. Thoracentesis performed with ultrasound guidance has lower risk of pneumothorax and bleeding complications. Future research should focus on the clinical effectiveness of point-of-care ultrasound in the routine management of pleural effusions ...
Point-of-Care Diagnostics Microfluidics Lab-on-a-Chip Global Health Viral Diseases Infectious Disease Biosensors Biodetection Biosecurity
Point-of-Care Diagnostics Microfluidics Lab-on-a-Chip Global Health Viral Diseases Infectious Disease Biosensors Biodetection Biosecurity
DE KOCK, S H; OTTO, S F y JOUBERT, G. The feasibility of determining the position of an endotracheal tube in neonates by using bedside ultrasonography compared with chest radiographs. S. Afr. j. child health [online]. 2015, vol.9, n.1, pp.3-5. ISSN 1999-7671.. BACKGROUND: Neonates in our neonatal intensive care unit (NICU) receive a large amount of radiation with X-rays (XRs) being done daily, even more often with reintubation, repositioning of endotracheal tubes (ETTs) and confirmation thereof, which has been our NICU policy for many yearsOBJECTIVE: To investigate the feasibility of determining the position of ETTs in neonates by using bedside ultrasonography (BUS), and to compare the results with those obtained from chest XR (CXR) findingsMETHODS: A prospective, cross-sectional study was done on intubated neonates in the NICU at Universitas Academic Hospital, Bloemfontein, to determine the position of ETTs by using BUSRESULTS: Thirty intubated patients included in this study had a median age ...
China Med-Du-S8exp Portable Echocardiography Color Doppler Ultrasound Machine, Find details about China High Class 4D Color Doppler, Ultrasound from Med-Du-S8exp Portable Echocardiography Color Doppler Ultrasound Machine - Guangzhou Med Equipment Co., Ltd.
by Jill Scoggins, HSC communications and marketing - last modified Oct 09, 2014 09:48 AM. A third-year medical student at the University of Louisville has led a group of researchers from five universities in determining that bedside ultrasound is cost-effective as well.. With colleagues from Columbia University, Northwestern University, George Washington University, Jefferson Medical College and UofL, Alexander Thai will present results from the study, Cost Effectiveness of Implementation of Point-of-Care Ultrasound in a Pediatric Emergency Department, at the American Academy of Pediatrics National Conference and Exhibition in San Diego.. Thai will make his presentation at the pre-conference Section on Emergency Medicine on Friday, Oct. 10, at 3:45 p.m. PDT.. The clinical value of bedside ultrasound - known as point-of-care ultrasound or POCUS - has long been established. What Thai and his colleagues, including In K. Kim, M.D., of UofLs Department of Pediatrics Emergency Medicine Division, ...
1 Peeling, R., Holmes, K., Mabey, D., Ronald, A. (2006). Rapid tests for sexually transmitted infections (STIs): the way forward. Sexually Transmitted Infections, 82 Suppl 5, v1-6.. 2 Ministerial Advisory Committee on AIDS Sexual Health and Hepatitis. (2011). National HIV Testing Policy: Commonwealth Government Department of Health and Ageing, 2011.. 3 Guidasci, T. (2009). Fourth generation point of care HIV screening. Clinical Laboratory International, 33(3), 26-28.. 4 Therapeutic Goods Administration. (2012, 17 December). Alere Determine HIV 1/2 Ag/Ab Combo test: information for consumers. Australian Government Department of Health and Ageing (DoHA). Retrieved from: www.tga.gov.au. 5 Prestage, G., Brown, G., Keen, P. (2012). Barriers to HIV testing among Australian gay men. Sexual Health, 9(5), 453-58.. 6 Conway, D., Holt, M., McNulty, A., Couldwell, D., Smith, D., Davies, S, et al. (2013). Field performance of the Alere Determine HIV Combo assay in a large Australian multicentre study in a ...
GTPS, widely known as trochanteric bursitis, encompasses a spectrum of disorders (gluteal tendinopathy, tears, bursitis, and ITB syndrome) that are difficult to distinguish by clinical exam alone. Better understanding of US imaging characteristics in relation to clinical symptoms may be helpful in identifying those patients who would most benefit from corticosteroid injections and other non-operative treatment options.. Point-of-care musculoskeletal US use has been shown to reduce repeated hospital appointments, improve accuracy of diagnosis, and provide expedited treatment, thus improving quality of care in an outpatient musculoskeletal clinic. US assessment is not routinely included in the management of GTPS patients and ideal imaging modalities are not established. ...
OjoGel technology may allow for faster identification of serious eye injuries, Labriola said. With a rapid point-of-care device such as this, anyone in an emergency department could perform a test and know within minutes if the patient needs urgent surgery to save their vision.. Ascorbic acid, also known as vitamin C, is found in high concentrations in the fluid inside the eye, called aqueous humor, but normally has very low concentration in tears.. Deep damage to the cornea from trauma or incisional surgery releases aqueous humor into the tear film, which increases the concentration of ascorbic acid in tears to a measurably higher level than that found in normal eyes, said Pan, who is also affiliated with the Beckman Institute for Advanced Science and Technology at Illinois. OjoGel offers a unique biosensing technique that provides an effective and simple method for testing ascorbic acid in a point-of-care delivery system, Pan added.. A tiny teardrop is all thats needed to cause a ...
TY - JOUR. T1 - Hand-carried cardiac ultrasound (HCU) device. T2 - Recommendations regarding new technology. A report from the echocardiography task force on new technology of the nomenclature and standards committee of the American Society of Echocardiography. AU - Seward, James B.. AU - Douglas, Pamela S.. AU - Erbel, Raimund. AU - Kerber, Richard H.. AU - Kronzon, Itzhak. AU - Rakowski, Harry. AU - Sahn, L. David J.. AU - Sisk, Eric J.. AU - Tajik, A. Jamil. AU - Wann, Samuel. N1 - Copyright: Copyright 2017 Elsevier B.V., All rights reserved.. PY - 2002/4. Y1 - 2002/4. N2 - The newest introduction to echocardiography is a hand-carried ultrasound (HCU) device. It is a small echocardiographic machine that typically weighs less than 6 lb and can obtain echocardiographic images and data. However, neither the device nor the context of the examination fulfills the criteria for a comprehensive or complete echocardiographic examination. The American Society of Echocardiography believes that HCU will ...
The current situation in our neonatal intensive care unit (NICU) at Universitas Academic Hospital, Bloemfontein, is that all neonates undergo a daily routine X-ray (XR) (either chest or abdominal, or both). Those neonates who are intubated are X-rayed more often, for example, with reintubation, repositioning of endotracheal tubes (ETTs) or when deterioration of their condition is noted. This has been our NICU policy for many years. Consequently, neonates are exposed to high levels of radiation, which should be reduced where possible.. A literature search suggested that a study to determine the position of an ETT using bedside ultrasonography (BUS) would be feasible and possible. Several studies have confirmed that BUS can accurately determine the placing of ETTs in a paediatric ICU setting.[1-3] Ultrasound (US) and chest radiography agreed on ETT placement in 83% of cases, with US having a sensitivity of 91% and a specificity of 50%.[4] Hosseini et al.[5] used right subcostal US with good ...
The patient was admitted to the obstetric service and started on broad-spectrum antibiotics for incomplete septic abortion. She underwent a vacuum-assisted dilation and curettage with removal of uterine contents. Surgical pathology revealed degenerating and focal necrotic chorionic villi consistent with intra-uterine pregnancy. While rare in developed countries, septic abortion is a life-threatening infection of the placenta and fetus of a previable pregnancy typically associated with unsafe abortion practices.1 Diagnosis is made clinically and confirmed by ultrasound, computed tomography or magnetic resonance imaging that can show an enlarged uterus with hemorrhage, retained intrauterine material, free fluid, abscess formation and/or air. 2 Intrauterine air is theorized to arise from gas-forming organisms or secondary to perforation from unsafe abortion practices. The ultrasonographic finding of air in the uterus must be recognized by the emergency physician in order to expedite ED and ...
Emergency Medicine residents at CHUK in Kigali, Rwanda experienced the glory of friendly competition in Point of Care Ultrasound in the first ever edition of Pass and Play. As a visiting fellow working with PURE, I had the opportunity to lecture to the residency during conference days every Wednesday. Instead of image review, I created a competition for the residents inspired by similar competitions in the US. A cross between jeopardy and plain old pimping, the residents divided into teams by classes and were challenged to cases with ultrasound acquisition and image interpretation. Across the board there was excellent performance, including the 1st year residents who have had quite limited exposure to point of care ultrasound. Despite my attempts to stump the 3rd year residents, they were an unstoppable force. The final jeopardy question was unanticipated by the group since it reverted back to the basics of physics in ultrasound. A senior resident came through at the last moment to explain ...
Cohort 1 enrolled 48 patients, vs. 114 patients for cohort 2. Twelve patients in cohort 1 had a POCUS (25%) vs 89 in cohort 2 (78%) ( p , 0.0001; odds ratio [OR] 0.09 (95% confidence interval [CI] 0.04-0.20). Emergency physician (EP) successful aspiration: 89.1% POCUS vs. 24.5% NUS ( p , 0.0001; OR 25 [95% CI 10-59]). Combined EP/ENT successful aspiration: 99.0% POCUS vs. 80.3% NUS ( p , 0.0001; OR 24 [95% CI 3-193]). ENT consultation:12.9% POCUS vs. 65.6% NUS ( p , 0.0001; OR 0.07 [95% CI 0.03-0.17]). CT usage: 23.8% POCUS vs. 37.7% NUS ( p = 0.07; OR 0.51 [95% CI 0.25-1.02]). Return visits: 3.96% POCUS vs. 18.0% NUS ( p = 0.004; OR 0.18 [95% CI 0.05-0.61]).. ...
Eight hundred forty-five participants were included for analysis; 331 (39%) had a ureteral stone. The global performance of the STONE score was superior to physician gestalt (area under the receiver operating characteristic curve=0.78 [95% confidence interval {CI} 0.74 to 0.81] versus 0.68 [95% CI 0.64 to 0.71]). The prevalence of ureteral stone on CT scan ranged from 14% (95% CI 9% to 19%) to 73% (95% CI 67% to 78%) in the low-, moderate-, and high-score groups. The sensitivity and specificity of a high score were 53% (95% CI 48% to 59%) and 87% (95% CI 84% to 90%), respectively.. ...
Interview with Andrew D. Krahn, M.D.,FHRS, head of the division of cardiology at St. Pauls Hospital, and professor of medicine at the University of British Columbia, and vice president of the Heart Rhythm Society (HRS). He is an expert in long QT syndrome (LQTS) and is involved with the National Long QT Registry. He explains the issues with the drugs being used to treat coronavirus (COVID-19, SARS-CoV-2) patients and why these combined with the cardiac impact of the virus is causing prolonged ECG QT segment prolongation, leading to deadly arrhythmias. COVID-19 can cause myocarditis that causes QT prolongation and the front-line COVID drugs hydroxychloroquine and azithromycin also cause QT prolongation.. The U.S. Food and Drug Administration (FDA) issued a Drug Safety Communication April 23, 2020, reminding doctors there are serious side effects when using hydroxychloroquine and chloroquine in the off-label use to treat COVID-19 patients. This includes potentially life-threatening heart rhythm ...
TY - JOUR. T1 - Assessment of a point-of-care lactate monitor in emergency admissions of adult horses to a referral hospital. AU - Tennent-Brown, Brett S.. AU - Wilkins, Pamela A.. AU - Lindborg, Sue. AU - Russell, Gail. AU - Boston, Raymond C.. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2007/9. Y1 - 2007/9. N2 - Background: Blood lactate concentration [LAC] is considered a useful indicator of disease severity in horses. Agreement of point-of-care (POC) lactate monitors with laboratory standards has not been established for clinically abnormal horses. Hypothesis: It was hypothesized that results from a POC lactate monitor would be in agreement with a laboratory-based measurement of [LAC]. Animals: The study included adult horses presented for emergency evaluation. Methods: A prospective observational study was performed. [LAC] was measured with whole blood (AWB) and plasma (APL) by means of a POC monitor (Accutrend) and compared with results from whole blood ...
The recent revolution in digital technologies and information processing methods present important opportunities to transform the way optical imaging is performed, particularly toward improving the throughput of microscopes while at the same time reducing their relative cost and complexity. Lensfree computational microscopy is rapidly emerging toward this end, and by discarding lenses and other bulky optical components of conventional imaging systems, and relying on digital computation instead, it can achieve both reflection and transmission mode microscopy over a large field-of-view within compact, cost-effective and mechanically robust architectures. Such high throughput and miniaturized imaging devices can provide a complementary toolset for telemedicine applications and point-of-care diagnostics by facilitating complex and critical tasks such as cytometry and microscopic analysis of e.g., blood smears, Papanicolaou (Pap) tests and tissue samples. In this article, the basics of these lensfree ...
Point-of-care ultrasound (POCUS) systems are becoming a common sight in nephrology departments and renal dialysis clinics, helping clinical staff to evaluate and effectively access the vasculature of dialysis patients. Dr. Jean-Yves Bosc, a nephrologist and vascular doctor working at the nonprofit private health establishment AIDER SANTÉ in the South of France, has been a
Rutgers New Jersey Medical School is pleased to offer a two-day hands-on point-of-care ultrasonography course for clinicians. This course is designed for physicians, physician assistants, and advanced practice nurse practitioners interested in integrating ultrasonography into their clinical practice.. Learners will rotate through SHORT LECTURES, SMALL GROUP IMAGE INTERPRETATION SESSIONS, and HANDS-ON LEARNING with LIVE HUMAN MODELS, PERIPHERAL IV, CENTRAL LINE, & THORACENTESIS task trainers.. The course leaders are nationally recognized experts in the field of point-of-care ultrasonography and regularly teach ultrasonography courses at CHEST.. This activity is approved for 14 AMA PRA Category 1 Credits.. Date: Jan 31, 2020 - 12:00pm - 8:30pm; Feb 1, 2020 - 7:00am - 5: ...
These are the first national hospice/palliative care symptom control performance data to demonstrate improvements in clinical outcomes at a service level as a result of routine data collection and systematic feedback.
Video articles in JoVE about venous thromboembolism include Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis, A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis, Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography, Intravital Microscopy and Thrombus Induction in the Earlobe of a Hairless Mouse, Mouse Complete Stasis Model of Inferior Vena Cava Thrombosis, Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood, The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation.
Ramin Artang, MD, discusses a University of Nebraska Medical Center study aimed at improving monitoring of NOACs. NOACs were initially thought to not require monitoring, however the practice of anticoagulating a patient requires some level of monitoring to ensure therapy is not only safe but is also effective. Evaluating outcomes alone in an anticoagulated patient is insufficient, particularly when the patient is having or could have an adverse event. There are many commercial approaches to monitoring NOACs, with the newest technology being TEG6S. The advantage of TEG6S is primarily that it is a point-of-care assay. With this assay, a clinician can know within 10 minutes whether a patient is in the sub- or supra- therapeutic range with a NOAC drug. , TV Network
Infectious diseases are the leading causes of death around the world. Point-of-care devices using nucleic acid amplification are sensitive enough to diagnose these diseases, however, often require complex and time-intensive sample preparation steps that are not integrated with the detection process. A rapid, sensitive, and integrated sample-to-result diagnostic device will permit disease treatment planning at the point-of-care. Paper-based detection assays are a promising platform to integrate the sample preparation and detection, with minimal infrastructure, equipment, and user involvement. To integrate sample preparation with detection on paper-based assays, timing and delivery of sample fluid flow needs to be controlled. Here we use thermally responsive materials (e.g. wax) to create a micro valve on a nitrocellulose membrane in order to automate fluid flow and minimize user involvement. The ease-of-fabrication, lot-to-lot variability and consistency of the dispensing methods are compared. After
TY - JOUR. T1 - Systematic review on antigens for serodiagnosis of visceral leishmaniasis, with a focus on East Africa. AU - Kühne, Vera. AU - Rezaei, Zahra. AU - Pitzinger, Paul. AU - Büscher, Philippe. N1 - FTX. PY - 2019. Y1 - 2019. N2 - BackgroundAccurate and accessible diagnosis is key for the control of visceral leishmaniasis (VL). Yet, current diagnostic tests for VL have severe limitations: they are invasive or not suitable as point of care (POC) test or their performance is suboptimal in East Africa. We analysed the antigens in the VL serodiagnostics development pipeline to identify shortcomings and to propose strategies in the development of an alternative POC test for VL in East Africa.ObjectivesThe objective of this study was to identify and to analyse all antigens for VL serodiagnosis that have been published before 2018 in order to identify candidates and gaps in the pipeline for a new POC test in East Africa.MethodsA systematic literature search was performed on PubMed for ...
Methods First, an item-reduction analysis of the TULIA (48 gestures) was performed, based on the methods of classical test theory and on a larger sample of patients with stroke (n=133) and matched healthy controls (n=50). Stepwise elimination of items resulted in a set of 12 items, demonstrating high internal consistency (Cronbach alpha=0.92). The six-point scoring method of the TULIA was dichotomised to the score levels pass and fail. In the second part of this study the validity of the AST was assessed prospectively in a new cohort of patients with stroke (n=31) by using the Pearson correlation analysis and binary classification display with the TULIA. ...
BACKGROUND: Salmonella enterica can significantly impact management of animal facilities. Comprehensive screening is essential for effective control in high-risk populations. Availability of reliable point-of-care diagnostic tests would facilitate these efforts. HYPOTHESIS/OBJECTIVES: Compare the ability of commercially available rapid diagnostic assays (2 lateral flow immunoassays [LFIs], DNA hybridization [DNAH], real-time PCR [qPCR]), and culture to detect common serotypes of S. enterica in feces. ANIMALS: n/a. METHODS: In an experimental study, 112 S. enterica isolates were randomly selected from the 10 most common serotypes recovered at a veterinary hospital. Archived isolates were amplified in broth and standardized inocula (100 colony forming units) were incubated with equine feces in tetrathionate broth (TET). Cultures were tested in a blinded fashion by using LFIs, DNAH, qPCR, and culture. RESULTS: The LFIs detected 84% and 67% of isolates, respectively, but reactivity varied among ...
AUTHORS: Kim, Won Ho MD, PhD et al. Anesthesia & Analgesia: May, 2017. BACKGROUND: Although point-of-care (POC) analyzers are commonly used during liver transplantation (LT), the accuracy of hematocrit measurement using a POC analyzer has not been evaluated. In this retrospective observational study, we aimed to evaluate the accuracy of hematocrit measurement using a POC analyzer and identify potential contributors to the measurement error and their influence on mistransfusion during LT.. METHODS: We retrospectively collected 6461 pairs of simultaneous intraoperative hematocrit measurements using POC analyzers and laboratory devices during LTs in 901 patients. The agreement of hematocrit measurements was assessed using Bland-Altman analysis for repeated measurements, while the incidence and magnitude of hematocrit measurement error were compared among 16 different laboratory abnormality categories. A generalized estimating equation analysis was performed to identify potential contributors to ...
Scientists at the University of Pennsylvania have developed a point-of-care device for detecting the Zika virus for under $2 a pop. Its about the size of a can of coke and can be operated by just about anyone, and even outside the clinic. A patient simply spits into the receptacle and after a while a paper test strip changes its color to a shade of blue if a Zika virus is detected.. Previously available tests either take a lot of time, produce too many false negatives, or require expensive equipment that limit their usability. RT-PCR, particularly, works well but requires precise sample management to amplify the DNA.. The new test uses a technique called loop-mediated isothermal amplification (LAMP) to grow the viral DNA. One problem of applying LAMP in the past has been developing so-called primers, short DNA strings that complement the DNA of the viral target. The researchers used computational techniques to identify spots on the Zika DNA that are unique to that virus, which were integrated ...
POC/Point-of-Care Hematology and Flow Cytometry Markets 2021: Physician Offices, Emergency Rooms, Operating Suites, ICUs/CCUs, Cancer Clinics, Ambulatory Care Centers, Surgery Centers, Nursing Homes, Birth Centers - Market research report and industry analysis - 10944502
Cyril Kuriakose, MD. 0730-1800 Bedside Ultrasound Course **. Soprano & Picasso. Faculty: Robert Kollpainter, PA-C, Chair; Francisco Norman, PA-C; Jonathan Monti, PA-C; Jeremy Amayo, PA-C; Nicole Heidenreich, PA-C; Thomas Pahl, PA-C; Hana Dubsky PA-C; Kim Kuphal, PA-C. This is a one-day, intensive course designed to change the way its participants think about point-of-care-ultrasound. This course will take a turn from the traditional, systems based, model of teaching and will instead begin with the most commonly utilized protocol in emergency medicine, the eFAST exam, and build on it to gain a further and more comprehensive understanding of the RUSH and BLUE protocols. This course will also take an in-depth look at procedural ultrasound to gain understanding of the proven techniques to get the needle where it needs to go as safely as possible.. This course is a collaborative effort by the Association of Physicians in Cardiothoracic and Vascular Surgery and the Society of Point-of-Care Ultrasound ...
[835 Pages Report] Check for Discount on 2016 POC/Point-of-Care Infectious Disease Testing Market: Physician Offices/Group Practices, Emergency Rooms, Ambulatory Care Centers, Surgery Centers, Birth Centers--Volume and Sales Segment Forecasts, Technology Trends, Instrumentation Review report by Venture Planning Group. This new 835-page report from VPGMarketResearch contains 80 tables,...
Complications may occur after a liver transplantation, therefore proper monitoring and care in the post-operation phase plays a very important role. Sometimes, monitoring and care for patients from abroad is difficult due to a variety of reasons, e.g., different care facilities. The objective of our research for this paper is to design, implement and evaluate a home monitoring and decision support infrastructure for international children who underwent liver transplant operation. A point-of-care device and the PedsQL questionnaire were used in patients home environment for measuring the blood parameters and assessing quality of life. By using a tablet PC and a specially developed software, the measured results were able to be transmitted to the health care providers via internet. So far, the developed infrastructure has been evaluated with four international patients/families transferring 38 records of blood test. The evaluation showed that the home monitoring and decision support ...
2016 US Hematology and Flow Cytometry Testing in Hospitals, Commercial Labs and POC/Point-of-Care Locations is a market research report available at US $11500 for a Single User PDF License from RnR Market Research Reports Library.
The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differences between aPTT reagents stored in a dried format to select the most suitable formulations to be used for the development of point-of-care diagnostic devices used for monitoring of unfractionated heparin dose response. METHODS: Ten reagents were analysed in terms of their performance in liquid and in dried form after storage for 24 h and 14 days. Performance was assessed by measurement of the clotting time (CT) as evidenced by the onset of thrombin formation using a chromogenic thrombin substrate in plasma samples activated with these formulations. RESULTS: Reagents in all of the three forms tested (liquid, 24 h and 14 days) resulted in significant shortening of CTs in comparison with the nonactivated plasma CT. Liquids returned more rapid CTs in comparison with dried
Introduction: The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differences between aPTT reagents stored in a dried format to select the most suitable formulations to be used for the development of point-of-care diagnostic devices used for monitoring of unfractionated heparin dose response. Methods: Ten reagents were analysed in terms of their performance in liquid and in dried form after storage for 24 h and 14 days. Performance was assessed by measurement of the clotting time (CT) as evidenced by the onset of thrombin formation using a chromogenic thrombin substrate in plasma samples activated with these formulations. Results: Reagents in all of the three forms tested (liquid, 24 h and 14 days) resulted in significant shortening of CTs in comparison with the nonactivated plasma CT. Liquids returned more rapid CTs in comparison
Quality of Care Improve your Leapfrog Hospital Safety Score. Quality matters! CMS will no longer compensate hospitals for certain hospital-acquired conditions, including iatrogenic pneumothorax. Point-of-care ultrasound can help eliminate this complication and improve hospital quality scores View Case Study Efficiency Increase Physician Efficiency with Bedside Ultrasound The
Source: ISTAT 2001: At the beginning of 2011, there were 608,493 people residing in Genoa, of whom 47% were male and 53% were female. PubMed Central. PubMed Central. For the period before ICD-10 implementation (1970-2002) and when Istat data (2004-2005) are lacking, mesothelioma deaths were estimated through statistical models (logistic, Poisson). Cox, Dana C.; Edwards, Michael Todd. Utility of a point-of-care device for rapid determination of prothrombin time in trauma patients: a preliminary study. The opening lines of How the Grinch Stole Christmas! EFFECTS OF CYCLIC FLEXURAL FATIGUE ON PORCINE BIOPROSTHETIC HEART VALVE HETEROGRAFT BIOMATERIALS. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Per quanto riguarda la richiesta di uno studio epidemiologico descrittivo, la informo, sempre la Cimini scrive a me, che le cause di morte della popolazione di ogni comune ...
Fasting guidelines are used to prevent perioperative aspiration but they are only reliable in healthy elective patients. Point-of-care gastric ultrasound allows qualitative and quantitative evaluation of gastric contents at the bedside. This case report describes the use of serial gastric point-of-care ultrasound to evaluate the effect of prokinetic therapy with domperidone and erythromycin in an elective surgical patient with multiple comorbidities who presented with a full stomach. ...
MEDFORD, N.Y., Dec. 3, 2013-- Chembio Diagnostics, Inc., a leader in point-of-care diagnostic tests for infectious diseases, announces that Lawrence A. Siebert, Chief Executive Officer, will present at the LD Micro VI: The Main Event Conference to be held December 3- 5, 2013 in Los Angeles, CA. Mr.
Over-diagnosis of malaria among African children results in mismanagement of non-malaria infections. Limited laboratory capacity makes it difficult to implement policies that recommend pre-treatment confirmation of infections so a new approach with a package for on-the-spot management of fevers was evaluated. Febrile children presenting to outpatient clinic were randomized to receive either a test-treat package (history with clinical examination; point-of-care tests; choice of artesunate-amodiaquine, co-amoxiclav and/or paracetamol) or routine outpatient care in a secondary health care facility in Kumasi, Ghana. A diagnosis of malaria, bacterial, viral or mixed malarial and bacterial infections was made using pre-defined criteria. Outcome was resolution of all symptoms including fever on day 7. The median age of the patients was 37.5 months (IQR: 19 to 66 months), with 56.7% being males. Compared to routine care the test-treat package resulted in less diagnoses of malaria, (37.2% vs 46.2%, p = ...
Increasing U.S. testing capabilities. While the FDA will no longer accept EUAs for LDTs, it will still continue to review requests for point-of-care tests, home collection tests, and any other tests that may alleviate national shortages. This includes high-throughput, widely distributed tests, as the Administration hopes to increase the countrys overall testing capacity and accessibility.. The FDA stated: We are currently in a different phase of the pandemic with respect to tests than we were previously, where many COVID-19 tests are now authorized to be run in labs. We prioritize review of EUA requests for tests taking into account a variety of factors, including those discussed in the Emergency Use Authorization of Medical Products and Related Authorities Guidance, such as the public health need for the product and the availability of the product.. Updates on 3D printed swabs. Within the new FAQs, the FDA has advised on which specimen types can be swab tested. As it stands, this includes ...
TRIVITRON HEALTHCARE PVT. LTD. - Exporter, Manufacturer, Distributor & Supplier of Biocard™ Dengue Combo Lateral Flow Assay Kit based in New Delhi, India
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With point-of-care testing, the ED doctor sustains workflow efficiency. POCT enables workflow efficiency through quick delivery of results and ease of staff workload.
/PRNewswire/ -- The COVID-19 pandemic prompted a transformation in the infectious disease point-of-care testing (POCT) market. The shift towards miniaturized...
Author Summary In tropical Africa, clinical laboratories capable of performing complicated diagnostic studies like PCR are rare and are almost always found in large cities. Moreover, a number of infectious diseases, many of them are emerging and neglected, may be quickly and reliably diagnosed only by molecular biology. This is one of the reasons why the repertoire of bacterial infectious diseases in tropical Africa is poorly known. The laboratory based on the Point-of-Care (POC) principle has been designed in order to resolve the time lag between test results and patient care, which is the critical point for the treatment. We report here the first successful experience of the installation of POC laboratory in rural Senegal. During the first year of the study (February 2011 to January 2012) we identified DNA from at least one pathogenic bacterium in 80/440 (18.2%) of the samples from febrile patients. In most of the cases it was relapsing fever and rickettsiosis agents. Malaria was diagnosed in 54 cases
Diagnostic Laboratory The laboratory plays a critical role in the diagnosis and management of drug-resistant TB. Test results must be available in a time frame that allows clinicians to make prompt patient management decisions. Many laboratory techniques used to confirm a TB diagnosis and to identify drug resistance were developed in the 1950s, 1960s, and 1970s. Substantial improvements have been made in culture techniques and in rapid methods in the past decade. However, these more accurate, rapid, and sophisticated methods have not been implemented widely, particularly in regions of the world where MDR TB and XDR TB are common and optimized algorithms for providing rapid point-of-care laboratory confirmation of TB and detection of drug resistance have not been established. To combat the growing problem of resistance to TB drugs, the most current methods need to be applied to their fullest capacity while better diagnostic tests are developed. The needs of the TB laboratory must be addressed to ...
MEDFORD, N.Y., Dec. 13, 2012-- Chembio Diagnostics, Inc., a leader in point-of-care diagnostic tests for infectious diseases, announces that an oral presentation and multiple poster presentations underscoring the clinical utility of the Companys Dual Path Platform ® rapid, point-of-care diagnostic tests are being presented at the 2012 HIV Diagnostics Conference being held December 12-14 at the Sheraton Atlanta Hotel.
Dengue is the most prevalent mosquito-borne viral infection worldwide and is the leading cause of illness and death in tropical/subtropical areas (,390 million people are infected). There are no approved vaccines or drugs against the virus. While most infections resolve without medical intervention, a significant fraction of dengue patients develop hemorrhagic fever and shock syndrome, which if untreated can be fatal. Early supportive care is critical for management of the fever and maintaining the blood volume during hemorrhage. Because the initial symptoms of dengue are similar to many other mosquito transmitted viral infections, early and accurate diagnosis of the disease is critical for these patients.. Generally, current dengue virus assays are not sensitive enough, too expensive and/or time-consuming resulting in delayed/misguided medical intervention in up to 50% of cases. In developing countries, the ease of access, availability of required infrastructure and the cost of diagnosis are ...
The NIAID Category B priority pathogen Entamoeba histolytica is a public health threat, especially as a cause of diarrhea in travelers to and immigrants from en...
This thesis contributes to the development of Lab-on-a-Chip systems that enables reliable, rapid medical diagnostics at the point-of-care. These contributions are focused on microfluidic Lab-on-a-Chip systems for sepsis diagnosis, autonomous sample-to-answer tests, and dried blood spot sampling.. Sepsis is a serious condition with high mortality and high costs for society and healthcare. To facilitate rapid and effective antibiotic treatment, improved sepsis diagnostics is needed. Diagnosis of sepsis requires the processing of relatively large blood volumes, creating a need for novel and effective techniques for the handling of large volume flows and pressures on chip. Components, materials, and manufacturing methods for pneumatically driven Lab-on-a-Chip systems have therefore been developed in this thesis. Microvalves, an essential component in many Lab-on-a-Chip systems have been the focus on several of the advances: a novel elastomeric material (Rubbery Off-Stoichiometric-Thiol-Ene-Epoxy) ...
This study was conducted to develop a simple, rapid, and accurate lateral flow immunoassay (LFIA) detection method for point-of-care diagnosis. The one-dot LFIA for aflatoxin B1 (AFB1) was based on the modified competitive binding format using competition between AFB1 and colloidal gold-AFB1-BSA conjugate for antibody binding sites in the test zone. A Smartphone-based reading system consisting of a Samsung Galaxy S2 Smartphone, a LFIA reader, and a Smartphone application for the image acquisition and data analysis. The detection limit of one-dot LFIA for AFB1 is 5 μg/kg. This method provided semi-quantitative analysis of AFB1 samples in the range of 5 to 1,000 μg/kg. Using combination of the one-dot LFIA and the Smartphone-based reading system, it is possible to conduct a more fast and accurate point-of-care diagnosis.
This study was conducted to develop a simple, rapid, and accurate lateral flow immunoassay (LFIA) detection method for point-of-care diagnosis. The one-dot LFIA for aflatoxin B1 (AFB1) was based on the modified competitive binding format using competition between AFB1 and colloidal gold-AFB1-BSA conjugate for antibody binding sites in the test zone. A Smartphone-based reading system consisting of a Samsung Galaxy S2 Smartphone, a LFIA reader, and a Smartphone application for the image acquisition and data analysis. The detection limit of one-dot LFIA for AFB1 is 5 μg/kg. This method provided semi-quantitative analysis of AFB1 samples in the range of 5 to 1,000 μg/kg. Using combination of the one-dot LFIA and the Smartphone-based reading system, it is possible to conduct a more fast and accurate point-of-care diagnosis.
Point-of-care ultrasound performed by clinicians is a useful supplement in the treatment and assessment of patients. We aimed to investigate whether medical students with minimal training were able to successfully acquire and interpret ultrasound images using a pocket-size imaging device (PSID) as a supplement to their clinical practice. Thirty 5th year (of six) medical students volunteered to participate. They were each given a personal PSID device to use as a supplement to their physical examination during their allocated hospital terms. Prior to clinical placement the students were given three evenings of hands-on training with PSID by a board certified radiologist/cardiologist, including three short lectures (|20 min). The students were shown basic ultrasound techniques and taught to assess for basic, clinically relevant pathology. They were specifically instructed to assess for the presence or absence of reduced left ventricular function (assessed as mitral annular excursion | 10 mm), pericardial
Point-of-care ultrasound performed by clinicians is a useful supplement in the treatment and assessment of patients. We aimed to investigate whether medical students with minimal training were able to successfully acquire and interpret ultrasound images using a pocket-size imaging device (PSID) as a supplement to their clinical practice. Thirty 5th year (of six) medical students volunteered to participate. They were each given a personal PSID device to use as a supplement to their physical examination during their allocated hospital terms. Prior to clinical placement the students were given three evenings of hands-on training with PSID by a board certified radiologist/cardiologist, including three short lectures (|20 min). The students were shown basic ultrasound techniques and taught to assess for basic, clinically relevant pathology. They were specifically instructed to assess for the presence or absence of reduced left ventricular function (assessed as mitral annular excursion | 10 mm), pericardial
BACKGROUND: The SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus 2) is responsible for the infectious respiratory disease called COVID-19 (COronaVIrus Disease 2019). In response to the growing COVID-19 pandemic, point-of-care (POC) tests have been developed to detect specific antibodies, IgG and IgM, to SARS-CoV-2 virus in human whole blood. We conducted a prospective observational study to evaluate the performance of two POC tests, COVID-PRESTO® and COVID-DUO®, compared to the gold standard, RT-PCR (real-time reverse transcriptase polymerase chain reaction). METHODS: RT-PCR testing of SARS-Cov-2 was performed from nasopharyngeal swab specimens collected in adult patients visiting the infectious disease department at the hospital (Orléans, France). Capillary whole blood (CWB) samples from the fingertip taken at different time points after onset of the disease were tested with POC tests. The specificity and sensitivity of the rapid test kits compared to test of reference (RT-PCR) were ...
This thesis investigates the clinical impact of a point-of-care diagnostic strategy for pulmonary tuberculosis (TB) in a setting at the heart of the TB and human immunodeficiency virus (HIV) epidemics in rural KwaZulu-Natal, South Africa. Although the identification and prompt treatment of active pulmonary TB disease remains the cornerstone of global TB control strategies, weak diagnostic systems contribute to substantial delays and default during the diagnostic process. As new diagnostic technologies are developed, evidence is needed around how best to deliver them within health systems in order to maximize their impact. The impact of positioning of a molecular diagnostic system (Xpert MTB/RIF) was investigated in a cluster randomised trial. Clusters (two-week time periods) were randomised to one of two strategies: centralised laboratory Xpert MTB/RIF testing or point-of-care Xpert MTB/RIF at the clinic. The trial enrolled 1297 adults with symptoms of pulmonary TB who were HIV infected and/or ...
Authors: Kodogiannis, V.S. , Petrounias, I. , Lygouras, J.N. Article Type: Research Article Abstract: Current clinical diagnostics are based on biochemical, immunological or microbiological methods. However, these methods are operator dependent, time consuming, expensive and require special skills, and are, therefore, not suitable for point-of-care testing. Recent developments in gas-sensing technology and pattern recognition methods make electronic nose technology an interesting alternative for medical point-of-care devices. An electronic nose based on chemo-resistive sensors has been employed to identify in vitro 13 bacterial clinical isolates, collected from patients diagnosed with urinary tract infections, gastrointestinal and respiratory infections in a Public Health Laboratory environment. An intelligent unit consisting of an odour generation mechanism, rapid volatile delivery …and recovery system, and a classifier system based on a novel neuro-fuzzy system has been applied in the ...
by admin , Jan 19, 2009. The Piccolo xpress (Abaxis) comprehensive metabolic panel (CMP) recently became the first CMP to be granted Clinical Laboratory Improvement Amendments (CLIA)-waived status by the FDA. With this waiver, providers can now conduct comprehensive, lab-accurate chemistry analyses at the point-of-care in minutes under a simple certificate of waiver from the Centers for Medicare and Medicaid Services. The waiver eliminates some of the barriers that kept many physician offices from performing point-of-care blood analysis, allowing them to improve patient care and increase office efficiency. CMP test results give physicians a comprehensive health assessment that provides critical information for accurate diagnosing and triage of patients during their initial office visit. Instead of waiting multiple days for tests results from reference laboratories, physicians can ascertain an accurate assessment of health at the point-of-care. On-site testing also gives physicians the ability to ...
Cricothyrotomy is a difficult, infrequently performed lifesaving procedure. The objectives of the study were to develop a standardized ultrasound technique to sonographically identify the cricothyroid membrane (CM) and to evaluate the ability of emergency physicians (EPs) to apply the technique i...
BETHLEHEM, Pa., July 31, 2020 (GLOBE NEWSWIRE) - OraSure Technologies, Inc. (NASDAQ: OSUR), a leader in point-of-care diagnostic tests, specimen collection devices, and microbiome laboratory and analytical services, today announced that its OMNIgene®·ORAL (OM-505) saliva collection device is included in the U.S. Food and Drug Administration (FDA) Emergency Use Authorization (EUA) granted to Clinical Reference Laboratory (CRL), one of the largest privately held clinical testing laboratories in the United States, for SARS-CoV-2 testing. This is the fourth EUA to include a collection device manufactured and sold by the Companys DNA Genotek subsidiary.. The EUA authorizes CRL to use the OMNIgene®·ORAL device with CRL Rapid Response™, its saliva-based SARS-CoV-2 RT-PCR test that can be self-collected at home, work or any other setting, when COVID-19 infection is suspected by a healthcare provider. The saliva sample would be collected with the OMNIgene·ORAL (OM-505) saliva collection device, ...
one step syphilis test kits catologs and one step syphilis test kits manufacturers - 134 Guangdong one step syphilis test kits Manufacturers, Exporters & suppliers from China
Advances in cell biology, quantification, and identification procedures are essential to develop novel particle characterization tools on the diagnostics, biotechnology, pharmaceutical industry, and material science. Flow cytometry is a pivotal technology and meets the need for almost a century. Increase in todays demand for fast, precise, accurate, and low-cost point-of-care diagnostic tools and cell counting technologies necessitate further improvements for state-of-the-art flow cytometry platforms. These improvements are achievable using novel and precise particle focusing techniques, multiple detection methods, integrated fluidic, optical, and electronic units in the same workflow. Thanks to its indisputable advantages in such integrities, microfluidic flow cytometry platforms are attractive and promising tool for the future of next-generation flow cytometry technologies. In this thesis, we developed viscoelastic focusing technique compatible with optical, impedimetric, and imaging-based ...
Bedside ultrasound as an alternative to chest radiograph in detecting complications associated with central venous catheter placement: a retrospective cohort study
Abstract. Background: Non-muscle invasive bladder cancer (NMIBC) is associated with high rates of recurrence, resulting in frequent follow-up cystoscopies. We evaluated the use of two point-of-care tests - the nuclear matrix protein 22 (NMP22) and urinary bladder cancer antigen (UBC) Rapid - compared to routine follow-up in patients with a previous history of NMIBC.. Methods: 31 patients with cystoscopy-verified active bladder cancer, and 44 follow-up patients without disease as confirmed by cystoscopy were prospectively enrolled. All urine samples were analyzed by voided urine and bladder washing cytology, NMP22 and UBC rapid test (qualitatively and quantitatively). The best cutoff (highest Youden index; ≥6.7 ng/ml) for the quantitative UBC was determined by receiver operating characteristic curves.. Results: Voided urine and barbotage cytology resulted in a sensitivity of 25.8% and 32.3%, and a specificity of 100% and 100%, while the NMP22 showed a sensitivity and specificity of 12.9% and ...
In 1997 the World Health Organization (WHO) advocated increased access to diagnosis and treatment, as well as reinforcement of surveillance, for the control of sleeping sickness (human African trypanosomiasis, HAT). This coincided with the end of decades of civil conflicts in several endemic regions and negotiation of a sustainable supply of free curative drugs and, as a result, HAT is at its lowest level in 50 years. However, reported cases underestimate prevalence and downplay HAT when compared with data generated by advanced diagnostic capacity for human immunodeficiency virus (HIV), tuberculosis (TB) and malaria, and, because HAT case numbers fall between epidemics, diagnostics become less commercially appealing. Here recent trends in the development of diagnostics for sleeping sickness are considered and progress towards a much-needed sensitive, specific and affordable point-of-care diagnostic is assessed. ...
VANCOUVER, BRITISH COLUMBIA-(Marketwired - May 17, 2017) - VANC Pharmaceuticals Inc. (TSX VENTURE:VANC)(OTCQB:NUVPD) (VANC or the Company), a pharmaceutical company focused on the Canadian generic drug and over-the-counter (the OTC) markets, announces today it has entered into a Canada-wide distribution agreement for INSTI® HIV-1/HIV-2 Antibody Test (INSTI).. We are very pleased to have acquired the Canadian distribution rights to INSTI, commented Bob Rai, CEO. We are bringing to the pharmacists counter a rapid (less than one minute) point-of-care diagnostic for HIV allowing customers to rapidly access their information and we will be working with provincial pharmacist associations to finalize pre and post-test counselling guidelines, concluded Mr. Rai.. The INSTI® HIV-1/HIV-2 Antibody Test is a single use, rapid, flow-through in vitro qualitative immunoassay for the detection of antibodies to Human Immunodeficiency Virus Type 1 and Type 2 in human whole blood, finger stick blood, ...
LifeAssays AB (LifeAssays) is a diagnostic service company that develops, manufactures and markets in-vitro diagnostic products. The company offers point-of-care diagnostic testing for community, health centres, primary physicians and veterinarians.
ホーム , ジャーナル , Critical Reviews™ in Biomedical Engineering , 巻 47, 2019 発行 3 - SPECIAL ISSUE: SENSORS FOR ADVANCED MANUFACTURING, WEARABLES, AND POINT-OF-CARE DEVICES IN LA BELLE LABS AT ARIZONA STATE UNIVERSITY. PART II ...
To the Editor:. Previously, we reported false-negative results generated by the OSOM human chorionic gonadotropin (hCG)1 Combo test (Genzyme Diagnostics) (1) and certain lots of the hCG Cardinal Health Combo SP brand rapid test device (SP hCG rapid test; Cardinal Health) (2) owing to increased concentrations of hCG β core fragment (hCGβcf). We refer to this phenomenon as the variant hook effect. In a hospital setting, these false negatives pose a substantial risk of adverse outcomes if pregnant patients are given treatments that can affect the fetus. This observation was reported to the US Food and Drug Administration, but to our knowledge no action has been taken to change these devices. These false negatives also pose considerable risk to women at home, because a negative pregnancy test result may cause delays in prenatal care and continued engagement in behavior that can endanger the fetus. In view of the variable sensitivity of point-of-care (POC) and over-the-counter (OTC) devices to ...
TY - JOUR. T1 - Point-of-care ultrasonography by pediatric emergency medicine physicians. AU - Shook, Joan E.. AU - Ackerman, Alice D.. AU - Chun, Thomas H.. AU - Conners, Gregory P.. AU - Dudley, Nanette C.. AU - Fuchs, Susan M.. AU - Gorelick, Marc H.. AU - Lane, Natalie E.. AU - Moore, Brian R.. AU - Wright, Joseph L.. AU - Bird, Steven B.. AU - Blomkalns, Andra L.. AU - Carmody, Kristin. AU - Clem, Kathleen J.. AU - Courtney, D. Mark. AU - Diercks, Deborah B.. AU - Fields, Matthew. AU - Hockberger, Robert S.. AU - Holmes, James F.. AU - Hudak, Lauren. AU - Jones, Alan E.. AU - Kaji, Amy H.. AU - Martin, Ian B K. AU - Moore, Christopher. AU - Panebianco, Nova. AU - Benjamin, Lee S.. AU - Barata, Isabel A.. AU - Alade, Kiyetta. AU - Arms, Joseph. AU - Avarello, Jahn T.. AU - Baldwin, Steven. AU - Brown, Kathleen. AU - Cantor, Richard M.. AU - Cohen, Ariel. AU - Dietrich, Ann Marie. AU - Eakin, Paul J.. AU - Gausche-Hill, Marianne. AU - Gerardi, Michael. AU - Graham, Charles J.. AU - Holtzman, ...
TY - JOUR. T1 - Point-of-care ultrasonography by Pediatric Emergency medicine physicians. AU - Marin, Jennifer R.. AU - Lewiss, Resa E.. AU - Shook, Joan E.. AU - Ackerman, Alice D.. AU - Chun, Thomas H.. AU - Conners, Gregory P.. AU - Dudley, Nanette C.. AU - Fuchs, Susan M.. AU - Gorelick, Marc H.. AU - Lane, Natalie E.. AU - Moore, Brian R.. AU - Wright, Joseph L.. AU - Bird, Steven B.. AU - Blomkalns, Andra L.. AU - Carmody, Kristin. AU - Clem, Kathleen J.. AU - Courtney, D. Mark. AU - Diercks, Deborah B.. AU - Fields, Matthew. AU - Hockberger, Robert S.. AU - Holmes, James F.. AU - Hudak, Lauren. AU - Jones, Alan E.. AU - Kaji, Amy H.. AU - Martin, Ian B K. AU - Moore, Christopher. AU - Panebianco, Nova. AU - Benjamin, Lee S.. AU - Barata, Isabel A.. AU - Alade, Kiyetta. AU - Arms, Joseph. AU - Avarello, Jahn T.. AU - Baldwin, Steven. AU - Brown, Kathleen. AU - Cantor, Richard M.. AU - Cohen, Ariel. AU - Dietrich, Ann Marie. AU - Eakin, Paul J.. AU - Gausche-Hill, Marianne. AU - Gerardi, ...
The Simplexa Influenza A H1N1 (2009) test runs on the 3M Integrated Cycler under an exclusive global distribution agreement between Focus Diagnostics and 3M. The test employs real-time reverse transcription (RT) polymerase chain reaction (PCR) to qualitatively detect RNA of the 2009 H1N1 flu virus (2009 H1N1) in a patients nasal or nasopharyngeal specimens. It reports if a specimen is positive or negative for the presence of 2009 H1N1 or influenza A virus. By comparison, some flu tests, including rapid point-of-care influenza tests, can detect the presence of influenza A, but not differentiate the presence of 2009 H1N1. In addition to 2009 H1N1, influenza A viruses include some seasonal flu subtypes.. Thankfully, H1N1 is not currently a widespread public health problem, but reliable detection continues to be important to help manage high-risk patients, such as expectant mothers who have flu-like symptoms, said Jay M Lieberman, medical director, infectious diseases, Quest Diagnostics and Focus ...
Worldwide efforts have increased to develop rapid point-of-care Ebola tests as the deadly outbreak in West Africa has brought this disease to the forefront of international consciousness. Most recently, Luminex Corporation announced that the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) Diagnostics Division is developing rapid diagnostics for the Ebola virus using Luminexs xMAP technology. Other organizations working to develop similar tests include Corgenix Medical Corporation and Ugandas Makerere University.
Today, diagnosis is based on the measurement of a range of chemical parameters in accessible biological fluids such as blood and urine. In most cases, the samples are sent to a central laboratory for analysis and the results become available minutes, hours or even days later. Such delays can hamper timely diagnosis and impede medical decision-making. Nevertheless, a typical hospital laboratory has evolved over the years into a fully automated system of sample collection, bar coded patient identification, sample pre-treatment and passage via high throughput computer-controlled instruments. Human intervention is now limited to engineers rather than biomedical scientists.. However, in recent years, there has been something of a quiet revolution in diagnostics practice, with a discernible trend to take tests to the patient. Technological advances in assay chemistry, sensor and transducer platforms, electronic processing, instrumentation and miniaturisation has seen the emergence of alternate site ...
General practitioners increasingly use point-of-care ultrasonography despite a lack of evidence-based guidelines for their appropriate use in primary care. Little is known about the integration of ultrasonography in general practice consultations and the impact of its use on patient care. The purpose of this study was to explore general practitioners experiences of using ultrasonography in the primary care setting. Adopting an explorative phenomenological approach, we performed semi-structured interviews with general practitioners who used ultrasonography in their daily work. Thirteen general practitioners were recruited stepwise, aiming for maximum variation in background characteristics. Interviews were conducted at the general practitioners own clinic. Transcription and systematic text condensation analysis began immediately after conducting each interview. The general practitioners described using ultrasonography for both selected focused examinations and for explorative examinations. The two
The performance of the point-of-care Xpert HIV-1 viral load assay was evaluated against the Abbott RealTime PCR m2000rt system. A total of 96 plasma specimens ranging from 2.5 log10 copies ml-1 to 4.99 log10 copies ml-1 and proficiency testing panel specimens were used. Precision and accuracy were checked using the Pearson correlation co-efficient test and Bland-Altman analysis.. RESULTS ...
TY - JOUR. T1 - Point-of-Care Hemoglobin A1c. AU - OBrien, Matthew James. AU - Sacks, David B.. N1 - Funding Information: reported receiving support from the National Institute of Diabetes and Digestive and Kidney Diseases (R21-DK112066) and personal fees from Funding Information: Novo Nordisk. Dr Sacks reported receiving support from the National Institutes of Health Clinical Center Intramural Program and grants from the National Institutes of Health and serving as the chair on the National Glycohemoglobin Standardization Program steering committee.. PY - 2019/10/8. Y1 - 2019/10/8. UR - http://www.scopus.com/inward/record.url?scp=85072252129&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85072252129&partnerID=8YFLogxK. U2 - 10.1001/jama.2019.14063. DO - 10.1001/jama.2019.14063. M3 - Comment/debate. C2 - 31513231. AN - SCOPUS:85072252129. VL - 322. SP - 1404. EP - 1405. JO - JAMA - Journal of the American Medical Association. JF - JAMA - Journal of the American Medical ...
Online provider of Point-of-Care and Life Sciences qualitative industry trend analysis and quantitative research on market trends and market size including data on market segmentation, size and growth in US, UK, Europe, Asia and global markets. Providing market research reports, industry analysis, company profiles and country reports for strategic planning, competitive intelligence, marketing and business research.
Source: Seeking Alpha. Results from a 24-subject study in India assessing the safety and efficacy of autologous platelet rich plasma (PRP) processed with Cesca Therapeutics (NASDAQ:KOOL) point-of-care platform to treat chronic non-healing ulcers showed a treatment benefit. The data were just published in the Journal of Biomedical Science. Each patient received a single dose of PRP injections around the wound in conjunction with topical administration of autologous platelet gel. The process was completed within 30 minutes. The mean healing time was 8.2 weeks. All 24 participants experienced healing, with almost 71% (n=17/24) showing a 90% reduction in wound size. No adverse events were observed on the treatment day or during the 24 weeks of follow-up.. Interim CEO Dr. Chris Xu says, This peer-reviewed publication further validates our novel point-of-care platform for rapid cellular based therapies. As we continue to strengthen our team and evaluate Cescas clinical pipeline, these additional ...
No literature review exists on Mycoplasma pneumoniae-associated mild encephalitis/encepharopathy with a reversible splenial lesion (MERS). M.pneumoniae-associated MERS cases were searched till August 2016 using PubMed/Google for English/other-language publications and Ichushi ( http://www.jamas.or.jp/ ) for Japanese-language publications. Inclusion criteria were children fulfilling definition for encephalitis, M.pneumoniae infection, and neuroimaging showing hyperintensity in the splenium of the corpus callosum (SCC) alone (type I) or SCC/other brain areas (type II). We described two children with type I and II M.pneumoniae-associated MERS. Thirteen cases found by the search and our 2 cases were reviewed. Mean age, male/female ratio, duration of prodromal illness was 8.3 years, 1.5 and 3.5 days. The most common neurological symptom was drowsiness, followed by abnormal speech/behavior, ataxia, seizure, delirium, confusion, tremor, hallucination,
Short-term medical missions prevail as the most common form of international medical volunteerism, but they are ill-suited for medical education and training local providers in resource-limited settings. Objective: The purpose of this study is to evaluate the effectiveness of a longitudinal educational program in training clinicians how to perform point-of-care ultrasound (POCUS) in resource-limited clinics. Design: A retrospective study of a four-month POCUS training program was conducted with clinicians from a rural hospital in Haiti. The model included one-on-one, in-person POCUS teaching sessions by volunteer instructors from the United States and Europe. The Haitian trainees were assessed at the start of the program and at its conclusion by a direct objective structured clinical examination (OSCE), administered by the visiting instructors, with similar pre- and post- program ultrasound competency assessments.. ...
What is your approach to patients with suspected renal stones? Scan them all? Scan the first-timers? Scan the older patients? Its certainly easy to order a noncontrast CT scan, even directly from triage.. But what about ultrasound? It has been somewhat of a forgotten test for evaluating renal colic, perhaps in part because it relies upon secondary findings of renal stones, namely hydronephrosis and the absence of ureteral jets, because ureteral stones are not easily visualized with ultrasound. But perhaps its time to re-evaluate, given the cost and radiation involved with multiple CT scans.. A landmark multicenter study in 2014 compared noncontrast CT, radiology-performed ultrasound, and point-of-care ultrasound in evaluating patients with suspected renal colic. (New Engl J Med 2014;371[12]:1100.) This well-powered, prospective trial found no significant difference in diagnostic accuracy. The rate of significant adverse events was not found to be significantly different. The length of ED stay, ...
Bedside point-of-care ultrasound (POCUS) is increasingly used to assess medical patients. At present, no consensus exists for what POCUS curriculum is appropriate for internal medicine residency training programs. This document details the consensus-based recommendations by the Canadian Internal Medicine Ultrasound (CIMUS) group, comprising 39 members, representing 14 institutions across Canada. Guiding principles for selecting curricular content were determined a priori. Consensus was defined as agreement by at least 80% of the members on POCUS applications deemed appropriate for teaching and assessment of trainees in the core (internal medicine postgraduate years [PGY] 1-3) and expanded (general internal medicine PGY 4-5) training programs ...
An adult male with a history of caecal adenocarcinoma and subsequent right hemicolectomy presented to the emergency department with abdominal pain, nausea and non-bilious emesis. He was diffusely tender to palpation across the abdomen with marked distention. His vital signs and laboratory tests were unremarkable. His abdominal pain improved with intravenous opioid medication. His urinalysis was negative. A point-of-care ultrasound (figure 1) was performed by the emergency … ...
Subramony, MD, et al.. Choledochal cysts are rare but serious bile duct abnormalities are found in young children, usually during the first year of life. They require urgent surgical intervention due to the risk of developing cholangiocarcinoma. Clinicians should consider this diagnosis and perform a point-of-care ultrasound (POCUS) when a child presents to the emergency department (ED) with findings of jaundice, abdominal pain, and the presence of an abdominal mass. We present the case of a six-year-old child presenting only with abdominal pain upon arrival to our ED and was ultimately diagnosed by POCUS to have a choledochal cyst.. ...
Division of Pulmonary & Critical Care Medicine. Dr. Badamosi, is a clinical assistant professor of Medicine at UT Southwestern, and his areas of interest include critical care ultrasonography, and cardiopulmonary resuscitation. He is a registered diagnostic cardiac sonographer. ...
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Resuscitation of the critically ill trauma patient involves a myriad of high-stakes, time-sensitive management decisions. The landscape is shifting rapidly: new evidence on hemostatic resuscitation and component therapy in hemorrhagic shock, peri-arrest point-of-care ultrasound, novel approaches to resuscitative thoracotomy and trauma RSI have at once clarified and muddied the waters. In this rapid-fire, case-based session, Petro and Hicks will debate some of the recent and potentially practice changing literature to assist with key inflection points in the care of the sickest -- and sometimes deadest -- trauma patients, and engage in some trauma dogmalysis in the process.. ...
Comprehensive biomedical research must continue its crucial role in preparing the world for the next pandemic or other far-reaching public health emergency, whether it be caused by a novel influenza strain, Ebola, or some other transmissible pathogen, Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases (NIAID) and colleagues wrote in a commentary in the Journal of the American Medical Association (JAMA) yesterday.. The basic research portfolio leads naturally into and is complemented by investments in countermeasure development, the experts write. Although treatments and vaccines are essential countermeasures, so too are rapid, deployable, and point-of-care diagnostics. The latter are key to an effective response in an evolving pandemic.. Faucis coauthors are Hilary D. Marston, MD, MPH, NIAID medical officer and policy advisor, and Catharine I. Paules, MD, NIAID clinical associate. Fauci also highlighted this topic in a keynote address today at IDWeek in ...
A test strip for conducting a lateral flow assay for detection of an analyte in a sample that contains cells and fluid is provided, as well as methods for making and using the test strip. This test strip is commercially usable, for example, in a diagnostic device at a point of care for detection of analytes in whole blood.
The objective of this study Linking Infectious and Narcology Care (LINC) is to improve upon the treat and retain dimensions of the seek, test, treat, and retain paradigm in Eastern Europe. We will implement and assess a behavioral and structural intervention in Russia designed to support and motivate HIV-infected narcology heroin dependent patients (i.e., IDUs) to engage (i.e., initiate and retain) in HIV medical care and ultimately improve their HIV outcomes.. LINC is a clinical model designed to coordinate narcology and HIV systems of care using elements shown to facilitate engagement in medical care: HIV case management and point-of-care CD4 testing. The central hypothesis is that an intervention that involves coordination between the narcology and HIV systems via HIV case management delivered by a peer to help motivate and reduce barriers to HIV care will lead to engagement in HIV care.. Implementation research recognizes that effective interventions may not translate successfully across ...
In both the said steps, your skin and body doesnt get harmed at all. Also it has Belt clip, for easy attachment & use while walking and this massager comes with six months Warranty from date of invoice generation for free by registering on manufacturer website within 15 days. 886 515 Please, I am Dr ouattara from Burkina Faso,west Africa.can I have a proforma facture for a pre owned Tens is in treating muscle spasms and pain. The white mini ultrasound therapy is a machine that produces ultrasonic waves of 1MHz that gives a massaging effect to the tender parts of the muscles and helps in curing neuromuscular and muscular skeletal diseases. It provides nerve stimulation/ Tens (2channel) and can be used by the physiotherapist or the patients for pain relieving. The Wall Motion Tracking provides immediate visual and quantitative access to global and regional myocardial wall motion dynamics in 2D and 3D. You can adjust its strength for massaging with different massaging modes with 6 massage ...