BACKGROUND: Multidrug resistance is a worrying cause of treatment failure in bacterial infections. The search of bioactive constituents from medicinal plants against multidrug resistant (MDR) bacteria has significantly evolved in the two last decades. In the present study, twenty-two compounds (three terpenoids, eleven phenolics and eight alkaloids) isolated from three Cameroonian medicinal plants, namely Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis, as well as the crude extracts were tested for their antibacterial activities against Mycobacterium tuberculosis and Gram-negative bacteria amongst which were MDR active efflux pumps expressing phenotypes. METHODS: The microplate alamar blue assay (MABA) and the broth microdilution methods were used to determine the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of the studied samples. RESULTS: The results of the MIC determinations indicate that, the best crude extract was that from G. ...
BACKGROUND Natural products are well recognized as sources of drugs in several human ailments. In the present work, we carried out a preliminary screening of six natural compounds, xanthone V(1) (1); 2-acetylfuro-1,4-naphthoquinone (2); physcion (3); bisvismiaquinone (4); vismiaquinone (5); 1,8-dihydroxy-3-geranyloxy-6-methylanthraquinone (6) against MiaPaCa-2 pancreatic and CCRF-CEM leukemia cells and their multidrug-resistant subline, CEM/ADR5000. Compounds 1 and 2 were then tested in several other cancer cells and their possible mode of action were investigated. METHODOLOGY/FINDINGS The tested compounds were previously isolated from the Cameroonian medicinal plants Vismia laurentii (1, 3, 4, 5 and 6) and Newbouldia laevis (2). The preliminary cytotoxicity results allowed the selection of xanthone V(1) and 2-acetylfuro-1,4-naphthoquinone, which were then tested on a panel of cancer cell lines. The study was also extended to the analysis of cell cycle distribution, apoptosis induction, caspase 3/7
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Carcinoma of the cervix is the second most common cancer among women worldwide especially in the developing world. Due to severe reported cytotoxic tendenciesby anticancer drugs, newer therapies from natural products are desirable. This work therefore aims to partially purify pro-apoptotic agents from indigenous natural products and to investigate the mechanism of action of the selected plant fractions.Sixteen indigenous medicinal plants were collected from South West Nigeria. Plant extracts were fractionated into hexane (HF), chloroform (CF), ethylacetate (EAF), methanol (MF) and water (WF) fractions using solvent-solvent partitioning and polyamide adsorption chromatography. The resultant ninety-six test fractions were screened for lethality potential using brine shrimp lethality (BSL) assay. Fractions with LC50 less than 10 ug/ml were subjected to Water Soluble Tetrazolium (WST-1) cytotoxicity assay and apoptosis evaluations using: morphological assessment, flow cytometric analysis of ...
The application of medicinal plants in primary health care for people living with HIV/AIDS is well acknowledged in Tanzania. However, the conservation status of medicinal plants is questionable. This study aimed at assessing the conservation status of medicinal plants used to manage HIV/AIDS opportunistic infections in Rungwe District, Mbeya Region, Tanzania. Specifically, this study sought to: identify and document medicinal plant species used to manage HIV/AIDS opportunistic infections in the study area, explore indigenous knowledge of conserving medicinal plants in the study area, assess the wild population status of medicinal plant species used to manage HIV/AIDS opportunistic infections and to propose a conservation framework for medicinal plant species in the study area. This study employed a cross sectional research design through which data were collected at a single point in time. Ethnobotanical data were collected using questionnaires, key informants interviews, focus group ...
The use of medicinal plants as a fundamental component of the African traditional healthcare system is perhaps the oldest and the most assorted of all therapeutic systems. In many parts of rural Africa, traditional healers prescribing medicinal plants are the most easily accessible and affordable health resource available to the local community and at times the only therapy that subsists. Nonetheless, there is still a paucity of updated comprehensive compilation of promising medicinal plants from the African continent. The major focus of the present review is to provide an updated overview of 10 promising medicinal plants from the African biodiversity which have short- as well as long-term potential to be developed as future phytopharmaceuticals to treat and/or manage panoply of infectious and chronic conditions. In this endeavour, key scientific databases have been probed to investigate trends in the rapidly increasing number of scientific publications on African traditional medicinal plants. Within
Present study reveals the evaluation of phytochemical analysis and antibacterial activity in different solvents like Aqueous, Ethanol and Chloroform leaf of Phyllodium pulchellum (L.) Desv. The antibacterial
A medicinal plant is a plant that is used to attempt to maintain health, to be administered for a specific condition, or both, whether in modern medicine or in traditional medicine.[2][35] The Food and Agriculture Organization estimated in 2002 that over 50,000 medicinal plants are used across the world.[36] The Royal Botanic Gardens, Kew more conservatively estimated in 2016 that 17,810 plant species have a medicinal use, out of some 30,000 plants for which a use of any kind is documented.[37] In modern medicine, around a quarter[a] of the drugs prescribed to patients are derived from medicinal plants, and they are rigorously tested.[35][38] In other systems of medicine, medicinal plants may constitute the majority of what are often informal attempted treatments, not tested scientifically.[39] The World Health Organization estimates, without reliable data, that some 80 percent of the worlds population depends mainly on traditional medicine (including but not limited to plants); perhaps some ...
Indian Medicinal Plants: A Compendium of 500 Species - 5 Volume Set By P K Warrier, V P K Nambiar, C Ramankutty About the Book Indian Medicinal Plants, based on a treatise prepared by S. Raghunatha Iyer, a scholar of both Sanskrit and Ayurveda, aims to make an authoritative contribution to the field. The original
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Historically, people have collected plants and used them for treating and preventing various symptoms and diseases. To this day, people in East Asian countries use medicinal plants for traditional health care treatments. The World Health Organization (WHO) has acknowledged the importance of traditional medicines. Approximately 60,000 plant species are harvested mainly for medicinal usage in the world. These harvested medicinal plants are not only a major source for traditional medicine, but are also used as an important raw material for modern medicine, perfume, cosmetic products, etc. Demand for and trade in these medicinal plants have been increasing. The global reported trade in plants for medicinal purposes alone(customs code HS1211, a subset of the custom codes analysed in the International Trade Centre study)was valued at over USD 3.4 billion in 2014 (United Nations 2016). Most of these precious plants resources, however, are harvested in the wild and easily traded across borders outside ...
Historically, people have collected plants and used them for treating and preventing various symptoms and diseases. To this day, people in East Asian countries use medicinal plants for traditional health care treatments. The World Health Organization (WHO) has acknowledged the importance of traditional medicines. Approximately 60,000 plant species are harvested mainly for medicinal usage in the world. These harvested medicinal plants are not only a major source for traditional medicine, but are also used as an important raw material for modern medicine, perfume, cosmetic products, etc. Demand for and trade in these medicinal plants have been increasing. The global reported trade in plants for medicinal purposes alone(customs code HS1211, a subset of the custom codes analysed in the International Trade Centre study)was valued at over USD 3.4 billion in 2014 (United Nations 2016). Most of these precious plants resources, however, are harvested in the wild and easily traded across borders outside ...
Echinops kebericho, endemic to Ethiopia, is a critically endangered medicinal plant. It is among the most important medicinal plants of the country, valued primarily for its root parts. The commercial harvesting and sale of roots of E. kebericho have threatened local populations. This study aimed to develop micropropagation protocol for E. kebericho using shoot tip explants. The study started with seed germination test using seeds stored for different months. Shoot tips from in vitro germinated seedlings were cultured on shoot initiation MS media supplemented with 0, 0.1, 0.5, 1.0, 1.5 and 2.0 mg/l BAP or KN alone. Explants were cultured on shoot proliferation media fortified with Kinetin, BAP, and TDZ each at 0.0, 0.5, 1.0, 2.5, 3.0 and 5.0 mg/l either alone or in combination with 0.0, 0.1, 0.25 and 0.5 mg/l NAA. For rooting, full, half and 1/3 strength MS media supplemented with IBA and NAA alone each at 0, 0.05, 0.1, 0.5, 1.0, 1.5 and 2.5 mg/l were used. Growth regulator free MS medium was used as
IST OF MEDICINAL PLANTS (HERBS) - MALAYALAM NAME, (മലയാളതില്‍ ഉള്ള ആയുര്‍വേദ ചെടികളുടെ പേരുകള്‍ ) SANSKIRT NAME, BOTANICAL NAME , A compilation work on Ayurvedic Indian Medicinal Plants. You can get all necessary information about Medicinal Plants including its Botanical names, morphology, classification , therapeutic uses, Names in different languages, synonyms, habitat , Chemical present in Medicinal plants , Systemic action in nervous, digestive system etc., properties, parts used ,dosage, formulations or Yogas in Ayurveda , research works & pictures etc
Medicinal Plants of the World is a comprehensive and scientifically accurate guide to the best-known and most important medicinal plants, including those of special commercial or historical interest.
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Bansode, T., Gupta, A., Shinde, B., & Bk, S. (2017). ASSESSMENT OF ANTIDIABETIC POTENTIAL OF TRADITIONAL MEDICINAL PLANTS IN HUMAN WHOLE BLOOD SAMPLES. Innovare Journal of Health Sciences, 5(2). Retrieved from https://innovareacademics.in/journals/index.php/ijhs/article/view/ ...
Background The study of traditional knowledge of medicinal plants has led to discoveries that have helped combat diseases and improve healthcare. However, the development of quantitative measures that can assist our quest for new medicinal plants has not greatly advanced in recent years. Phylogenetic tools have entered many scientific fields in the last two decades to provide explanatory power, but have been overlooked in ethnomedicinal studies. Several studies show that medicinal properties are not randomly distributed in plant phylogenies, suggesting that phylogeny shapes ethnobotanical use. Nevertheless, empirical studies that explicitly combine ethnobotanical and phylogenetic information are scarce. Methodology/Principal Findings In this study, we borrowed tools from community ecology phylogenetics to quantify significance of phylogenetic signal in medicinal properties in plants and identify nodes on phylogenies with high bioscreening potential. To do this, we produced an ethnomedicinal review
Looking for medicinal plants? Find out information about medicinal plants. plants used as natural medicines. This practice has existed since prehistoric times. There are three ways in which plants have been found useful in... Explanation of medicinal plants
Medicinal Plants of India|list of Indian herbal plants|Herbals used in Ayurveda medicines|Medicinal plant database|A-Z list of medicinal plant used in Ayurveda|Oushada Sasyangal-Ayurvedic Medicinal Plants
Medicinal Plants of India|list of Indian herbal plants|Herbals used in Ayurveda medicines|Medicinal plant database|A-Z list of medicinal plant used in Ayurveda|Oushada Sasyangal-Ayurvedic Medicinal Plants
Consumption of medicinal plants to overcome diseases is traditionally belongs to the characteristics of most cultures on this earth. Sudan has been a host and cradle to various ancient civilizations and developed a vast knowledge on traditional medicinal plants. The present study was undertaken to evaluate the antioxidant, antiangiogenic and cytotoxic activities of six Sudanese medicinal plants which have been traditionally used to treat neoplasia. Further the biological activities were correlated with phytochemical contents of the plant extracts. Different parts of the plants were subjected to sequential extraction method. Cytotoxicity of the extracts was determined by dimethylthiazol-2-yl)- 2,5diphenyl tetrazolium bromide (MTT) assay on 2 human cancer (colon and breast) and normal (endothelial and colon fibroblast) cells. Anti-angiogenic potential was tested using ex vivo rat aortic ring assay. DPPH (1,1-diphenyl-2-picrylhydrazyl) assay was conducted to screen the antioxidant capabilities of the
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INTRODUCTION. The use of plants for treating diseases is as old as the human species. Popular observations on the use and efficacy of medicinal plants significantly contribute to the disclosure of their therapeutic properties, so that they are frequently prescribed, even if their chemical constituents are not always completely known. All over the globe, especially in South American countries, the use of medicinal plants has significantly supported primary health care (1). From 250 to 500 thousand plant species are estimated to exist on the planet, and only between 1 and 10% are used as food by humans and other animals (2). Brazil has the worlds highest biodiversity, accounting for over 20% of the total number of known species. This country presents the most diverse flora, with more than 55 thousand described species, which corresponds to 22% of the global total. Such biodiversity is followed by a wide acceptance of the medicinal plant use (3). Most of the Brazilian population (80%) consumes ...
Effects of Fruits Extracts of Three Medicinal Plants on the Blood Glucose Level of Glucose-induced Hyperglycemic and Normal Rabbit Models
Background and objectives: In review of traditional Persian medicine (TPM) literature concerning multi drug therapy, a group of medicinal plants that are called convoy drugs, agents which penetrate fast into whole or specific part of the body and accelerate delivery of drugs into specific target has been mentioned. In this study, the inhibitory effect of the aqueous extracts of some selected medicinal plants on P-glycoprotein (P-gp) was assessed in order to determine the possibility of herb-drug interactions. Methods: P-gp inhibitory effect of aqueous extracts (250 µg/mL) from some medicinal plants and verapamile (5 µg/mL) was measured using flow cytometry by Rhodamine 123 (Rh123) in Caco2 cell line. Inhibition percent of each sample (%) was compared with a control group (Caco-2 cell with Rh 123). Results: According to the results pennyroyal, aniseed (p|0.001), celery seed, melon seed and white agaric extract (p|0.01) exhibited the highest Rh123 percent in Caco-2 cells that could be associated with
Growers and producers should have adequate knowledge of the medicinal plant concerned. This should include botanical identification, cultivation characteristics and environmental requirements (soil type, soil pH, fertility, plant spacing and light requirements), as well as the means of harvest and storage.. All personnel (including field workers) involved in the propagation, cultivation, harvest and post-harvest processing stages of medicinal plant production should maintain appropriate personal hygiene and should have received training regarding their hygiene responsibilities.. Only properly trained personnel, wearing appropriate protective clothing (such as overalls, gloves, helmet, goggles, face mask), should apply agrochemicals.. Growers and producers should receive instruction on all issues relevant to the protection of the environment, conservation of medicinal plant species, and proper agricultural stewardship.. For further information, see section 4.7.. ...
|i|Journal of Diseases and Medicinal Plants (JDMP)|/i| publishes bi-monthly papers in the areas of pharmacology, toxicology, Neuroscience, Pathology, plant Biochemistry, animal Biochemistry, Biochemistry, Bio-organic Chemistry and medicinal Chemistry. The journal presents original papers, reviews and letters. The primary goal of this journal is to advance the understanding for the use of medicinal plants in the treatment of Diseases such as Leukemia, Breast cancer, HIV/AIDS, Cardiovascular diseases, Diabetes and other Diseases. The journal is addressed to scientists and other specialists interested in Medicinal plant research, teaching and techniques.
|i|Journal of Diseases and Medicinal Plants (JDMP)|/i| publishes bi-monthly papers in the areas of pharmacology, toxicology, Neuroscience, Pathology, plant Biochemistry, animal Biochemistry, Biochemistry, Bio-organic Chemistry and medicinal Chemistry. The journal presents original papers, reviews and letters. The primary goal of this journal is to advance the understanding for the use of medicinal plants in the treatment of Diseases such as Leukemia, Breast cancer, HIV/AIDS, Cardiovascular diseases, Diabetes and other Diseases. The journal is addressed to scientists and other specialists interested in Medicinal plant research, teaching and techniques.
|i|Journal of Diseases and Medicinal Plants (JDMP)|/i| publishes bi-monthly papers in the areas of pharmacology, toxicology, Neuroscience, Pathology, plant Biochemistry, animal Biochemistry, Biochemistry, Bio-organic Chemistry and medicinal Chemistry. The journal presents original papers, reviews and letters. The primary goal of this journal is to advance the understanding for the use of medicinal plants in the treatment of Diseases such as Leukemia, Breast cancer, HIV/AIDS, Cardiovascular diseases, Diabetes and other Diseases. The journal is addressed to scientists and other specialists interested in Medicinal plant research, teaching and techniques.
Numerous side effects of synthetic drugs have caused medicinal plants to be regarded in recent decades as a reliable source of new drugs. Regarding the analgesic effects of many plants that are pointed in traditional medicine of Iran, many studies have been performed in this field that have caused need to be reviewed. In this study, different methods of testing pain, analgesic activity and possible compounds of medicinal plants and also the possible mechanisms actions of these plants are presented. The data presented in this review paper provide scientific information that might be used for isolation of potentially active compounds from some of these medicinal plants in future.. ...
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Medicinal plants are possible sources for future novel antioxidant compounds in food and pharmaceutical formulations. Recent attention on medicinal plants emanates from their long historical utilisati
Sphaeranthus indicus is an important medicinal plant, which is used to cure various illnesses. The present study is the first investigation of the antimicrobial, antioxidant and phytochemical analysis of Sphaeranthus indicus from Chhattisgarh, India. The whole plant and plant parts were extracted with polar and non-polar solvents such as water, methanol, ethyl acetate and hexane to assess various bioactivities. The antimicrobial and antioxidant activities were performed by ager well diffusion method and ferrous reducing capacity, respectively; However free radical scavenging activity was analyzed using DMPD and DPPH scavenging assay. The DMPD and DPPH assay were performed in a time dependent manner. Qualitative and quantitative analysis were performed for the total phytochemicals present in the plant extracts. The total content of phenols, flavonoids and terpenoids was analyzed by colorimetric methods. Ethyl acetate and hexane extract of plant inflorescence and stem exhibited significant antibacterial
9789380138541, Medicinal Plants: Biodiversity, Conservation and Traditional Knowledge (In 4 Volumes), , A K Srivastava, Swastik Publications, `Medicinal Plants' are an essential part of traditional health care systems. Their gathering and cultivation
This research work concerns with the pharmacological screening of herbal extract for their antihypertensive action as well as the bioassay-directed fractionation of some medicinal plants, this is also resulted in the isolation of active principle from indigenous medicinal plants.Hypertension (elevated blood pressure) is one of the most common disease of modern times The drugs so far available are not only beyond the reach of a common man, but also have serious side effects, lacking curative properties thus limiting their therapeutic use. It is alarming that 12 million lives lost annually due to various cardio-vascular troubles mainly hypertension. Many medicinal plants are used in traditional system of medicine for the treatment of hypertension which require further detailed pharmacological investigation. However little systematic scientific studies with particular reference to antihypertensive activity has been undertaken on these plants. Pakistan is very rich in herbal wealth and research on ...
Millions of people worldwide depend upon medicinal plants for their healthcare needs. However, environmental damage is increasing the threat of plant extinction and jeopardising access to natural resources.. BGCI is working to link plant conservation with improvements in human well-being through a project for threatened medicinal species to help ensure on-going access to vital plant resources.. You can support our project and help make a difference to community health and plant conservation. Please contact us directly to find out more about this and other projects which use plant diversity to improve livelihoods and well-being.. ...