As in drug discovery and development, mass spectrometry has become essential at all stages for establishing the safety and efficacy of botanical dietary supplements. Applications of mass spectrometry to the development of botanical dietary supplements include preclinical studies of the mechanisms of action (., proteomic target identification and validation); identification of active natural products using high resolution tandem mass spectrometry; chemical standardization using UHPLC-MS/MS; and studies of metabolism, absorption and toxicity of active compounds using high resolution and UHPLC-MS/MS. Clinical applications of mass spectrometry include evaluation of the potential for drug-botanical interactions; investigation of the pharmacokinetics of active compounds; and quantitative analysis of biomarkers of efficacy during Phase I and II and clinical trials of safety and efficacy of botanical dietary supplements.. ...
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USPs Botanical Dietary Supplements and Herbal Medicines Expert Committee is responsible for the development of new and revision of existing monographs and their associated reference materials for botanical dietary supplements and herbal medicine ingredients. The expert committee addresses U.S. and global standards. The expert committee was formed to: ...
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Greetings! Eric Bakker. Naturopath from New Zealand. Thanks for tuning in to my video. Im going to talk about wheat grass today. Wheat grass and Candida yeast infections. Wheat Grass is an interesting topic. Ive been in this business for almost 30 years now and Ive seen a lot of trends come and go. I think wheat grass is a very good food, but I also think that its very overrated. Just like barley grass, spirulina, all these green kind of drinks. Bernard Jensen, the well-known iridologist and chiropractor from Escondido in California. He was a big fan of Ann Wigmores work; I think she came from Baltimore originally. Wigmore is a Lithuanian nutritionist with a very big interest in detoxification and cleansing. She had the Hippocrates Center on the Gulf Coast in Australia for many years. What a remarkable lady. I remember reading an article in a magazine: Sexy at 60, and there was this really stunning looking lady - I think she was about 65 years of age. It was Ann Wigmore. Ann Wigmore was ...
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The reason that it has such a high chlorophyll content is because we use wheat grass juice powder as opposed to just wheat grass powder. Wheat grass powder can contain a lot of fibre. In addition our grass is grown in a field and not in a tray which optimises chlorophyll content.. Average chlorophyll content in wheat grass is 320mg/100g. The 100g is squeezed to make the juice. Grass fibre content is around 22% so from 100g grass we get about 78g grass juice with a total of 320mg chlorophyll. This 78g is then dehydrated in a ratio of 30:1 and becomes 2.6g wheat grass juice powder 320mg of chlorophyll.. In 4g Wheat grass juice we therefore have 492mg chlorophyll.. ...
The purpose of this study was to examine the effects of phytoestrogens on luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Phytoestrogens are found in soybean based foods. The rats in a previous study were fed varying amounts of phytoestrogens, euthanized, and their pituitaries were preserved for further research, which is what was used in this study. In the previous study there was an increase in spermatogenesis for the low and high phytoestrogen diet group compared to the pre-treatment and medium group. The LH and FSH levels in the pituitaries were measured and the results were then analyzed to see if there was a correlation in LH and FSH levels to the phytoestrogen diet groups. A coomassie stain was done to ensure that the differences that were seen between the groups were because of varying amounts of phytoestrogens and not varying amounts of protein being loaded into the electrophoresis gels. There was no difference measured in any of the phytoestrogen diet groups for LHf3 and LH
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In herbalism, botanical supplements are commonly believed to be safe remedies, however, botanical supplements and dietary ingredients interact with transport and metabolic processes, affecting drug disposition. Although a large number of studies have described that botanical supplements interfere with drug metabolism, the mode of their interaction with drug transport processes is not well described. Such interactions may result in serious undesired effects and changed drug efficacy, therefore, some studies on interaction between botanical supplement ingredients and drug transporters such as P-gp and OATPs are described here, suggesting that the interaction between botanical supplements and the drug transporters is clinically significant.
In the study to review the sources, metabolism, potencies, and clinical effects of phytoestrogens on humans, posted in PubMed, suggested that phytoestrogens are among the dietary factors affording protection against cancer and heart disease in vegetarians. With this epidemiologic and cell line evidence, intervention studies are now an appropriate consideration to assess the clinical effects of phytoestrogens because of the potentially important health benefits associated with the consumption of foods containing these compounds ...
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Researchers in Canada reviewed 44 different herbal supplements, ranging from things like Ginkgo biloba, often thought to treat memory disorders, to St. Johns wort, which purportedly treats mild depression. Using a sophisticated method of DNA barcoding, a technique of genetic fingerprinting developed about a decade ago, scientists found that one-third of them were complete substitutions. Many of them simply contained fillers like wheat, rice and soybean.. This suggests that the problems are widespread and that quality control for many companies, whether through ignorance, incompetence or dishonesty, is unacceptable, David Schardt, a senior nutritionist at the Center for Science in the Public Interest, a safety and nutrition advocacy group, told The New York Times. Given these results, its hard to recommend any herbal supplements to consumers.. Other herbal supplements were discovered to be adulterated with ingredients not listed on the label. Ginkgo biloba, for instance, contained black ...
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The following 3rd party published noni research and studies on noni and noni juice benefits are available on PubMed.com. You can also find information on noni health related research at the UH Noni Website. NONI RESEARCH: 2008. J Ethnopharmacol. 2008 Feb 12;115(3):502-6. The effects of Morinda citrifolia L. (noni) on the immune system: Its molecular mechanisms of action. Palu AK, Kim AH, West BJ, Deng S, Jensen J, White L.. The aim of this study was to investigate the mechanisms involved in the immunomodulatory effects of Morinda citrifolia L. (noni) in vitro and in vivo in mice. In vitro, Tahitian Noni Juice (TNJ) and Noni fruit juice concentrates (NFJC) (1, 5mg/mL) potently activate cannabinoid 2 (CB2), but inhibit cannabinoid 1 (CB1) receptors in a concentration-dependant manner. In vivo, oral administration of TNJ ad libitum for 16 days decreased the production of IL-4, but increased the production of IFN-gamma. These results suggest that noni modulates the immune system via activating of ...
Humans have been using plants to support wellness for ages, and still do to this very day.** While our ancestors may have only been familiar with the herbs found growing near their homes, today we live in a world where the knowledge of traditional (and new-found!) herbs is readily available. Thanks to this supply of knowledge, many are taking a natural approach to supporting their healthy lifestyle goals by using herbal supplements containing plants found around the world.. At Piping Rock, were proud to offer you our growing selection of top-quality herbal supplements, featuring traditional and even rare herbs that can finally be yours without breaking the bank. Our herbal supplements are derived from all-natural herbal sources, such as roots, leaves, and flowers, and are available in an array of forms and formulas.. ...
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Botanical dietary supplements are often targeted by the mainstream media and scientific/medical communities as being unscientific and unsafe relative to prescription pharmaceuticals and over-the counter drugs. However, the relative risk of botanical medicines is largely overestimated and causal relationships between botanical remedies and significant adverse reactions pale in comparison to the frequency and magnitude of those observed with normal use of FDA-approved pharmaceuticals.
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Scarcely any things have been as disputable as herbal supplements have been as of late. Contingent upon who you tune in to, they are either the response to any difficult you have or they are the fallen angel in bodily form. Reality with regards to herbal supplements, however, is actually some place in the middle. Herbal supplements are more generally utilized now than in other time ever. This is on the grounds that numerous individuals have gone to herbal supplements so as to fill the holes in what they know to be unfortunate eating regimens that do not meet the base day by day prerequisites for some, numerous vital nutrients and minerals. Others have gone to herbal supplements so as to upgrade everything from their exercise systems to their memory and mental capacities. Considering the contention about whether it is sheltered to take herbal supplements or not, you likely marvel exactly what you can truly anticipate from taking herbal supplements.. The truth of the matter is that taking herbal ...
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Herbal therapy is also known as Phytotherapy or Phytomedicine. As you may recall from previous articles, the word phyto means plant. This form of cancer therapy focuses on herbal or botanical supplements have been used for centuries in dealing with a wide range of diseases. Many of these plants have been studied by pharmaceutical companies to isolate active ingredients for use in drugs.
Herbal therapy is also known as Phytotherapy or Phytomedicine. As you may recall from previous articles, the word phyto means plant. This form of cancer therapy focuses on herbal or botanical supplements have been used for centuries in dealing with a wide range of diseases. Many of these plants have been studied by pharmaceutical companies to isolate active ingredients for use in drugs.