Purified Native Ricinus Communis Agglutinin I Protein, Rhodamine labeled from Creative Biomart. Native Ricinus Communis Agglutinin I Protein, Rhodamine labeled can be used for research.
Purified Native Griffonia Simplicifolia Lectin I isolectin B4 Protein from Creative Biomart. Native Griffonia Simplicifolia Lectin I isolectin B4 Protein can be used for research.
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[button size=small text=MSDS & Datasheet link=/wp-content/uploads/media/BCDatasheets_C_10.26/BXXXX/B-2401-2.pdf]Anti-B Griffonia simplicifolia Le
[button size=small text=MSDS & Datasheet link=/wp-content/uploads/media/BCDatasheets_C_10.26/BXXXX/B-2402-2.pdf]Anti-Tk Griffonia simplicifolia L
Lectins, a well-known class of carbohydrate-binding proteins, are known to be important in a variety of biological processes, mediated through their carbohydrate specificities. Plant lectins are broadly divided into six classes based on their subunit folds. These are legume lectins (see ,PDOC00278,), jacalin-related lectins (JRLs), monocot mannose-binding lectins (see ,PDOC50927,), trefoil lectins, cyanovirin-N lectin, and hevein domain lectins. JRLs derive their name from jacalin, the first member to be identified from the seed of jackfruit. Based on the known sugar specificities, lectins in this family can be broadly divided into two classes: (1) the galactose-specific lectins and (2) the mannose/glucose-specific lectins [1,2,3,4,5]. The ~135-150 amino acid residue jacalin-type lectin domain adopts a β-prism-I fold comprised of three Greek keys (four stranded β-sheets) (see ,PDB:3APA,) [4]. Some proteins known to contain a jacalin-type lectin domain are listed below: ...
Griffonia simplicifolia is a coarse aggressive brier built-in to West Africa and Central Africa. It grows to about 3 m, and bears greenish flowers followed by atramentous pods. The seeds of the bulb are acclimated as an herbal supplement for their 5-hydroxytryptophan (5-HTP ) content. 5-Hydroxytryptophan is an important architecture block for the animal physique…
GSL II is affinity purified tetramer that contains a single type of 30 kDa subunit. It has insecticidal structure/function, the first GlcNAc binding legume lectin proven to have insecticidal activity.This lectin has a carbohydrate specificity for αGal and αGalNAc and elutes with galactose or N-acetylgalactosamine. Incr
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5 - HTP Natural Source 5- hydroxytryptophanNOW searches worldwide for high quality effective nutritional products that safely supply our customers needs. We supply a complete line of amino acids, vitamins, minerals, herb capsules, and herb extracts.Each Capsule Contains: 5-htp (5-hydroxytryptophan) 50mg (Griffonia simplicifolia seed)Other ingredients: White Rice Powder.Griffonia simplicifolia is an African Plant which is extracted to produce 5-HTP, the intermediate metabolite between the amino acid L-tryptophane and serotonin. Contains no yeast, wheat, corn, soy, milk, sugar, salt, colors or preservatives.Suggested Usage: As a dietary supplement, take 1 capsule daily, preferably at bedtime.Warning: If you are currently taking antidepressant medications please consult a physician prior to use. May cause drowsiness.
Though youve probably never heard of 5-HTP until recently, its actually been studied for more than 30 years. There have been several clinical trials that have proven just how well it helps with controlling hunger and losing weight. In this study, women who used this supplement before eating ate over 1,000 calories less than those who didnt. And in this study, women who took the supplement lost five times more weight over 12 weeks than those were taking a placebo.. If youre the type of person who always feels hungry and you have a hard time controlling your eating habits then 5-HTP may be just what you need to finally lose weight and keep your weight under control for the long run. ...
The role of individual carbohydrate-binding sites in the function of the potent anti-HIV lectin Griffithsin". Jie Xue, Yongguang Gao, Bart Hoorelbeke, Ioannis Kagiampakis, Bo Zhao, Borries Demeler, Jan Balzarini, and Patricia J. LiWang Molecular Pharmaceutics 4, 2613-2625 (2012).. Griffithsin (GRFT) is a lectin that has been shown to inhibit HIV infection by binding to high mannose glycan structures on the surface of gp120, and is among the most potent HIV entry inhibitors reported so far. However, important biochemical details on the antiviral mechanism of GRFT action remain unexplored. In order to understand the role of the three individual carbohydrate-binding sites (CBS) in GRFT, mutations were made at each site (D30A, D70A, and D112A), and the resulting mutants were investigated. NMR studies revealed that each GRFT variant was folded but showed significant peak movement on the carbohydrate-binding face of the protein. The wild-type and each point mutant protein appeared as tight dimers with ...
The legume lectins (or L-type lectins) are a family of sugar-binding proteins or lectins found in the seeds and, in smaller amounts, in the roots, stems, leaves and bark of plants belonging to the Fabaceae family. The exact function of the legume lectins in vivo is unknown but they are probably involved in the defense of plants against predators. Related proteins in other plant families and in animals have also been found. They have been used for decades as a model system for the study of protein-carbohydrate interactions, because they show an amazing variety of binding specificities and are easy to obtain and purify. Over the years, a quite impressive amount of structural data has been gathered. Well-studied members of this protein family include phytohemagglutinin and concanavalin A. The legume lectins use an ingenious framework for binding specific sugars. This framework consists of a conserved monosaccharide binding site in which four conserved residues from four separate regions in the ...
div class=citation vocab=http://schema.org/,,i class=fa fa-external-link-square fa-fw,,/i, Data from ,span resource=http://link.randwick.nsw.gov.au/resource/OT5uCBa3C_k/ typeof=CategoryCode http://bibfra.me/vocab/lite/Topic,,span property=name http://bibfra.me/vocab/lite/label,,a href=http://link.randwick.nsw.gov.au/resource/OT5uCBa3C_k/,Plant lectins,/a,,/span, - ,span property=potentialAction typeOf=OrganizeAction,,span property=agent typeof=LibrarySystem http://library.link/vocab/LibrarySystem resource=http://link.randwick.nsw.gov.au/,,span property=name http://bibfra.me/vocab/lite/label,,a property=url href=http://link.randwick.nsw.gov.au/,Randwick City Library,/a,,/span,,/span,,/span,,/span,,/div ...
Pisum sativum|/em| agglutinin is nearly identical in structure and carbohydrate specificity to |em|Lens culinaris|/em| agglutinin.
The binding of the plant lectin soybean agglutinin (SBA) to primary sensory neurones has been investigated in the rat. SBA binding was found in Lissauers tract and in laminae I and IIo of the dorsal horn at cervical, thoracic and lumbar levels. Morphometric analysis of the S1 dorsal root ganglia revealed that SBA binding was associated with the small diameter cell population, considered to be the cell bodies of unmyelinated afferent fibres (C-fibres). These findings suggest that SBA may be a useful ultrastructural marker for C-fibre terminals ...
Kilpatrick, D.C. Pusztai, A., Grant, G., Graham, C. and Ewen, S.W (1985) Tomato Lectin Resists Digestion in the Mammalian Alimentary Canal and Binds to Intestinal Villi without Deleterious Effects. FEBS Letters, 185, 299-305.
If regularly used, 5-HTP should be taken at night and L-Tyrosine in the morning. These two precursors to neurotransmitters work together and are needed to keep the neurotransmitters Dopamine at the correct level. Almost everyone in the United States should take Tyrosine in the morning and Tryptophan at night because Round-up depletes our food supplies and bodies of both these essential amino acids. To learn more about the impact of Round-up and related toxins on our metabolism, please click here. When taken as directed, our 5-HTP is completely safe and is an extract of Griffonia simplicifolia seeds from coastal West Africa. ...
FREE bottle of 5-HTP in NOVEMBER with every purchase of 2 bottles of 5-HTP. 5-HTP by Natures Rx is the highest quality 5-HTP available. 5-HTP is an all natural extract derived from the African plant Griffonia Simplicifolia. Research has shown that 5-HTP can aid weight loss by decreasing hunger and by promoting feelings of satisfaction. ...
Bead- and column-based separation methods rely heavily on the speed and ease of affinity binding systems. Ligands such as streptavidin, antibodies and lectins are used both to capture specifically-tagged targets and for the isolation of cells and biomolecules that naturally express the ligand binding partner. The unique saccharide-binding properties of plant lectins, such as Concanavalin A (Con A) have made them useful for the labeling and isolation of glycan-presenting cells and glycoproteins in serum and cell lysate. Lectins have additionally been used in cell adhesion studies, to effect lymphocyte activation, and to explore carbohydrate-based therapeutics.. Learn More ...
Bead- and column-based separation methods rely heavily on the speed and ease of affinity binding systems. Ligands such as streptavidin, antibodies and lectins are used both to capture specifically-tagged targets and for the isolation of cells and biomolecules that naturally express the ligand binding partner. The unique saccharide-binding properties of plant lectins, such as Concanavalin A (Con A) have made them useful for the labeling and isolation of glycan-presenting cells and glycoproteins in serum and cell lysate. Lectins have additionally been used in cell adhesion studies, to effect lymphocyte activation, and to explore carbohydrate-based therapeutics.. 了解更多 ...
According to their sugar recognition specificity, plant lectins are proposed as bioactive proteins with potential in cancer treatment and diagnosis. Helja is a mannose-specific jacalin-like lectin from sunflower which was shown to inhibit the growth of certain fungi. Here, we report its recombinant expression in a prokaryotic system and its activity in neurobalstoma cells. Helja coding sequence was fused to the pET-32 EK/LIC, the enterokinase/Ligation-independent cloning vector and a 35 kDa protein was obtained in Escherichia coli representing Helja coupled to thioredoxin (Trx). The identity of this protein was verified using anti-Helja antibodies. This chimera, named Trx-rHelja, was enriched in the soluble bacterial extracts and was purified using Ni+2-Sepharose and d-mannose-agarose chromatography. Trx-rHelja and the enterokinase-released recombinant Helja (rHelja) both displayed toxicity on human SH-SY5Y neuroblastomas. rHelja decreased the viability of these tumor cells by 75% according to the
cbsPredict :: DESCRIPTION Given a protein structure (PDB file), cbsPredict will identify potential carbohydrate-binding sites based on detection of coplanar, aromatic residues located on the protein surface. ::DEVEL
1wbl: Carbohydrate specificity and quaternary association in basic winged bean lectin: X-ray analysis of the lectin at 2.5 A resolution.
TY - JOUR. T1 - Distribution of Bandeiraea simplicifolia lectin binding sites in the genital organs of female and male mice. AU - Wu, T. C.. AU - Wan, Yu-Jui Yvonne. AU - Damjanov, I.. PY - 1983/6. Y1 - 1983/6. N2 - Fluorescein isothiocyanate labelled type I lectin from Bandeiraea simplicifolia (BSA-I) known for its specific binding to α-d-galactopyranosyl and 2-acetamido-2-deoxy-d-galactose groups, has been used to map the distribution of the lectin specific binding sites in the genital organs of female and male mice. In non-pregnant female mice, strong lectin reactivity was restricted to the epithelium of the distal oviduct, the cervix and vagina. In pregnant mice strong BSA-I reactivity was also noted in the epithelium of uterine glands from the time of implantation on day 5 onward. In the testis BSA-I bound selectively to sperm but did not react with other cells in the seminiferous tubules. In the proximal caput epididymis BSA-I reacted with the epithelial cells, the underlying basement ...
Enhances brain serotonin 5-Hydroxytryptophan (5-HTP) is an intermediate in the natural synthesis of the essential amino acid, tryptophan, to serotonin. The enzyme tryptophan hydroxylase adds a hydroxyl group (OH) to tryptophan, forming the 5-HTP intermediate. In the body, it converts to serotonin with the removal of a carboxyl group (COOH) by a second enzyme. Serotonin is an important neurotransmitter involved in the regulation of endocrine and brain activity responsible for emotion, appetite and sleep/wake cycles. In clinical studies, administration of 5-HTP supported serotonin production. The 5-HTP supplied in this supplement is derived from the Griffonia simplicifolia plant. Supplementation with 5-HTP encourages brain serotonin levels that can lead to positive effects on emotional well-being, appetite control, and wake/sleep cycles. each vegetable capsule contains: 5-hydroxytryptophan (Griffonia simplicifolia) 100 mg. (hypo-allergenic plant fiber added to complete capsule
Jacalin, isolated by affinity chromatography from jackfruit seeds, belongs to the family of galactose-binding lectins. Jacalin is a tetrameric two-chain lectin with a molecular weight of 66 kDa. Applications include isolating IgA from human serum, isolating human plasma glycoproteins and histochemistry. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the alpha-chain. The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, are explained by its protein structure. Artocarpus integrifolia lectin is supplied without preservatives as a lyophilized white to light-yellow powder, essentially salt-free. For laboratory use only.
The motility and the chemotactic response towards plant roots of Radopholus similis, after treatment with novel types of lectins, were examined in vitro by analysing movement tracks on agar plates. Six plant lectins belonging to five different lectin families and a banana thaumatin-like protein (BanTLP) were included in the experiment. A 1% concentration of Phaseolus vulgaris agglutinin (PHA) had an adverse effect on the motility of R. similis females: 63% showed no or very little movement on agar plates compared to an average of 33% for other lectins and 3% for the control treatment. A 0.05% concentration of PHA still reduced the motility of R. similis females by 75%. Concanavalin A and wheat germ agglutinin did not alter the chemotactic response towards plant roots, despite binding of both lectins to R. similis. In contrast, Galanthus nivalis agglutinin (GNA) reduced orientated movement of R. similis towards plant roots. Subsequently, secretions of R. similis were stained with Coomassie Brilliant Blue
Dolichos biflorus|/em| agglutinin is a glycoprotein with a molecular weight of about 111 kDa and consists of 4 subunits of approximately equal size. This lectin has a carbohydrate specificity toward α-linked N-acetylgalactosamine.
The mannose-binding lectin from snowdrop (Galanthus nivalis agglutinin; GNA) was produced in Escherichia coli and purified as a functional protein after denturation/renaturation. Incorporation of the four extra C-terminal residues recently revealed from X-ray crystallographic data demonstrated that these residues increase binding to the glycoprotein carboxypeptidase Y. However, no differences in activities were observed in haemagglutination assays when compared to native GNA and toxicity towards rice brown planthopper (Nilaparvata lugens, BPH) in artificial diet bioassays was unaltered. Site-directed mutagenesis of the carbohydrate-binding site of GNA provided evidence of a direct correlation between the binding potential of GNA to BPH gut glycoprotein receptors and the toxicity levels of GNA towards BPH nymphs. Functional recombinant plant lectins GNA and PHA (Phaseolus vulgaris agglutinin) were expressed in Pichia pastoris using native signal peptides or the Saccharomyces a-factor ...
Define Ulex europaeus. Ulex europaeus synonyms, Ulex europaeus pronunciation, Ulex europaeus translation, English dictionary definition of Ulex europaeus. Noun 1. Ulex europaeus - very spiny and dense evergreen shrub with fragrant golden-yellow flowers; common throughout western Europe furze, gorse, Irish...
Structural characterisation and analysis of two plant lectins : Scilla campanulata fetuin-binding protein (2.8AÌŠ), a novel two-domain member of the monocot mannose-binding superfamily & the legume lectin Lens culinaris in multiple crystal forms and in co ...
If you have ever seen a jackfruit, you will know that it is a massive fruit. Usually found at specialty or Asian grocery stores, jackfruits are the largest tree-borne fruits in the world. Each jackfruit can weight between 6-40 pounds. Some people get jackfruit and durian mixed up, but the jackfruit is much more palatable and grows much bigger. It has also been known to be a powerful cancer killer.. The jackfruit has lots of seeds inside, but the fruit is mainly composed of healthy starch and protein. In addition to being rich in healthy flavonoids, jackfruit has plenty of vitamin C, which is a powerful antioxidant that nourishes cells in the body. Each bulb of the fruit, which is made of sweet yellow flesh, is replete with a group of B-complex vitamins.. How Does Jackfruit Kill Cancer Cells?. As mentioned in the paragraph above, jackfruit contains a lot essential nutrients that benefit the entire body. Additionally, jackfruit has saponins, isoflavones, and lignans, which are phytonutrients that ...
Shop Jacalin-related lectin ELISA Kit, Recombinant Protein and Jacalin-related lectin Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
Erythrina cristagalli lectin or agglutinin (ECL/ECA) is affinity purified lectin consists of two subunits with molecular weights of 28,000 and 26,000. ECL binds to carbohydrate structure in membrane and serum glycoproteins of mammalian cells. The shape of the lectin binding domains may resemble cavity type with Galβ1-&
Definition of vicia villosa in the Definitions.net dictionary. Meaning of vicia villosa. What does vicia villosa mean? Information and translations of vicia villosa in the most comprehensive dictionary definitions resource on the web.
Bauhinia L.), é um gênero da família das leguminosas (Subfamília Cercidoideae[1]) com mais de 300 espécies sendo que no Brasil encontra-se cerca de 200 espécies.[2] Pertence a esse gênero a unha-de-vaca ou casco-de-vaca, árvore muito ornamental muito utilizada no paisagismo e na arborização urbana. ...
Thamotharan, Subbiah and Karthikeyan, Tangavelou and Kulkarni, Kiran A and Shetty, Kartika N and Surolia, Avadhesha and Vijayan, Mamannamana and Suguna, Kaza (2011) Modification of the sugar specificity of a plant lectin: structural studies on a point mutant of Erythrina corallodendron lectin. In: Acta Crystallographica Section D, 67 (Part 3). pp. 218-227. Kulkarni, Kiran A and Katiyar, Samiksha and Surolia, Avadhesha and Vijayan, Mamannamana and Suguna, Kaza (2008) Structure and sugar-specificity of basic winged-bean lectin: structures of new disaccharide complexes and a comparative study with other known disaccharide complexes of the lectin. In: Acta Crystallographica Section D: Biological Crystallography, 64 (7). pp. 730-737. Kulkarni, Kiran A and Katiyar, Samiksha and Surolia, Avadhesha and Vijayan, Mamannamana and Suguna, Kaza (2007) Generation of blood group specificity: New insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean ...
1992) The primary structure of stinging nettle (Urtica dioica agglutinin. FEBS. 299(2): 131-134. Bohm, E. and Maier, R. D. (1975) Weal-formation by Urtica dioica, An Intravital reaction. Z. Rechtsmed. 5, 76(1): 1-9. Bombardelli, E. , (1997) Urtica dioica L. Fitoterapia 68(5): 387- 402. Booth, V. H. and Bradford, M. P. (1963) Tocopherol contents of vegetables and fruits. Br. J. Nutr. 17: 575-581. Broekaert, W. , Parijs, J. , Joos, H. and Peumans, W. J. (1989) A Chitin-binding lectin from stinging nettle rhizomes with antifungal properties. Kavalali, G. and Akcasu, A. (1986) A study on the anticoagulant substance isolated from the leaves of Urtica dioica Thrombosis and Hemorrhagic Diseases proceedings of IVth Int. Meeting of Danubian League Against Thrombosis and Haemorrhagic Diseases. Sep. 25-28, Istanbul, Turkey, p. 244. Kavalali, G. and Diren, S¸. (1992) Urtica pilulifera L. Meyvalarinin Antimikrobik Etkileri. Prof. Dr. Sarim H. Çelebiog˘lu anisina bilimsel toplanti. Ist Ecz. Fak. I˙stanbul ...
The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins ...
Jackfruit is an aromatic, fleshy fruit celebrated for its delicious taste. But many people who enjoy eating jackfruit do so finally unaware of its many health benefits. Jackfruit is a tree species belong to the mulberry family. Jackfruit is very sweet and tasty, while the jackfruit is opened, you will find the bright yellow pods (when ripe) which can be eaten raw or cooked. When immature its flesh is green, and it can be made into a delicious vegetable dish. Jackfruit has a lot of health benefits ...
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Dr. Pusztai lost his job with RRI for expressing his opinions on the safety of genetically modified foods in a TV interview in 1998, while doing research on potatoes enhanced with Galanthus nivalis agglutinin, or GNA for short. GNA is a plant lectin derived from Galanthus nivalis, commonly known as Snowdrops (see picture below). Lectin is a protein usually derived from plants that has antibody properties (helps protect the plant from infection or disease). The experiments he was reporting on were testing on the effects of GNA, and the effects of the GM potato when supplemented to the diets of rats. He found when GNA was mixed in with the rats food as a protein supplement, there were no harmful effects. However, when the GM potato (modified with the GNA) was fed to the rats, it hindered growth as well as having other adverse effects. Pusztai said in a 2000 interview with the Canadian Health Coalition that many harmless substances when genetically altered, can become harmful (Interview with ...
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Franziska Beran, Sujit Adhikary, Sankar Gayen, Christian Ulrichs, Arunava Goswami: Genetic Polymorphism of Dolichos biflorus L. in India at the Seed Storage Level
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Galanthus nivalis lectin or agglutinin (GNA) is isolated from snowdrop bulbs. It has a molecular weight of 50 kDa and consists of four identical subu…
Judys Snowdrops - Collectors snowdrops for sale by mail order. Includes a comprehensive collection of photographs of rare snowdrops, or galanthus.