TY - JOUR. T1 - Preirradiation chemotherapy for very young children with brain tumors. AU - Jeng, Mei Jy. AU - Chang, Te Kau. AU - Wong, Tai-Tong. AU - Hsien, Yuh Lin. AU - Tang, Ran Bin. AU - Hwang, Betau. PY - 1993/6/1. Y1 - 1993/6/1. N2 - Standard management of malignant brain tumors includes either surgical resection alone or surgery followed by irradiation. However, neuroaxis irradiation administered to very young children for primary intracranial tumors is often associated with major late side effects. To delay irradiation and evaluate the efficacy of preirradiation chemotherapy, we treated 9 young children (aged less than 3 years), who had newly diagnosed brain tumors and underwent total or subtotal resection, with a combination of chemotherapy including vinblastine, cisplatin, and etoposide every 3-4 weeks for 6-14 courses between 1988 and 1992. There were malignat gliomas in four patients, medulloblastomas in three, and ependymomas in two. A response to preirradiation chemotherapy ...
Nitrogen and nitrogen-carbon dioxide gas mixtures were excited by 1.5 MeV protons from a Van De Graaff generator. Intensity versus pressure data were recorded and plotted for the first negative (lamda=3914.4A) and for the second positive (lamda=3371.3A) transitions of molecular nitrogen. With the use of theoretical equations and the experimental data the reaction rates, k, and collisional de-excitation cross sections were calculated. (Author)(*NITROGEN
TY - JOUR. T1 - Feasibility and efficacy of preirradiation chemotherapy for pediatric brain tumors. AU - Horowitz, M. E.. AU - Kun, L. E.. AU - Mulhern, R. K.. AU - Kovnar, E. H.. AU - Sanford, R. A.. AU - Hockenberger, B. M.. AU - Greeson, F. L.. AU - Langston, J. W.. AU - Fairclough, D. L.. AU - Jenkins, J. J.. PY - 1988/1/1. Y1 - 1988/1/1. N2 - Preirradiation chemotherapy is a potentially important component of combined treatment for brain tumors; however, concerns over its side effects and antitumor activity have impeded its evaluation in clinical trials. To determine the feasibility of administering such therapy to children, we assessed the responses of 38 brain tumor patients (median age, 2 years) to 12 weeks of combination chemotherapy given after surgical resection but before irradiation. Transient myelosuppression was noted in all patients, but was not associated with infections or complications of surgical wounds. The ability of the patients to perform activities of daily life, as ...
View Notes - 38-pldevresponmod from BIOL V04 at Ventura College. Plant Developmental Responses Phototropism positive Gravitropism positive negative Thigmotropism Old Fig. 36.11 Sun rising over
Appropriate leaf positioning is essential for optimizing photosynthesis and plant growth. However, it has not been elucidated how green leaves reach and maintain their position for capturing light. We show here the regulation of leaf positioning under blue light stimuli. When 1-week-old Arabidopsis seedlings grown under white light were transferred to red light (25 micromol m(-2) s(-1)) for 5 d, new petioles that appeared were almost horizontal and their leaves were curled and slanted downward. However, when a weak blue light from above (0.1 micromol m(-2) s(-1)) was superimposed on red light, the new petioles grew obliquely upward and the leaves were flat and horizontal. The leaf positioning required both phototropin1 (phot1) and nonphototropic hypocotyl 3 (NPH3), and resulted in enhanced plant growth. In an nph3 mutant, neither optimal leaf positioning nor leaf flattening by blue light was found, and blue light-induced growth enhancement was drastically reduced. When blue light was increased from 0.1
Acorda Therapeutics, Inc. (NASDAQ: ACOR) today announced additional data from its second Phase 3 clinical trial of Fampridine-SR (MS-F204) on walking ability in people with multiple sclerosis (MS) at the late breaking news session of the World Congress on Treatment and Research in Multiple Sclerosis, being held in Montreal, Canada. Previously, the Company announced the trial met its primary endpoint with a significantly greater proportion of people taking Fampridine-SR having a consistent improvement in walking speed compared to people taking placebo (42.9% vs. 9.3%), as measured by the Timed 25-Foot Walk (p less than 0.001). The study also met its secondary outcome measure, leg strength, showing a statistically significant increase in the Fampridine-SR Timed Walk responders compared to placebo (p = 0.028). New findings and information presented at the meeting from the study included: -- The response rate for Fampridine-SR treated patients was higher than placebo across all MS subtypes. Response ...
Sun flowers have a type of phototropic response called heliotropism (sun turning); the leaves and flower heads of young sunflowers follow the sun and their orientation therefore changes from east to west during the day.[7] The moments becomes a circadian response, if the plants are rotated 180 degrees, the old response pattern is followed for a few days with leaf orientation changing from west the east instead.[8] The leaf and flower bud phototropism occurs while the leaf petioles and stems are still actively growing and once mature the movements stop. The moment occurs as the petioles bend during the day and at night they unbend.[9]. ...
Three different methods of measuring the proliferative capacity of transplanted mouse bone marrow were used to study the effects of preirradiation of the recipient. Recipient mice were exposed to 700 R and given graded numbers of syngeneic bone marrow. 7 days were allowed for proliferation of these cells, and then the granulocytic or erythrocytic progeny was measured. The former was determined by the response to endotoxin, and the latter by the incorporation of radioactive iron into newly formed red blood cells. Erythropoiesis, therefore, could be measured independently from granulopoiesis by these techniques. The third method used was the spleen colony method of Till and McCulloch (5).. Recipient animals exposed to 150 R preirradiation, 7 days before 700 R and bone marrow transplantation, demonstrated an increase in erythropoiesis with a concommittant decrease in granulopoiesis compared to similar recipients not preirradiated. The spleen colony technique showed that while the number of colonies ...
High-density microelectrode arrays (HDMEA) have been recently introduced to study principles of neural function at high spatial resolution. However, the exact nature of the experimentally observed extracellular action potentials (EAPs) is still incompletely understood. The soma, axon and dendrites of a neuron can all exhibit regenerative action potentials that could be sensed with HDMEA electrodes. Here, we investigate the contribution of distinct neuronal sources of activity in HDMEA recordings from low-density neuronal cultures. We recorded EAPs with HDMEAs having 11,011 electrodes and then fixed and immunostained the cultures with β3-tubulin for high-resolution fluorescence imaging. Immunofluorescence images overlaid with the activity maps showed EAPs both at neuronal somata and distal neurites. Neuritic EAPs had mostly narrow triphasic shapes, consisting of a positive, a pronounced negative peak and a second positive peak. EAPs near somata had wide monophasic or biphasic shapes with a main negative
AstraZeneca today announced that the PEGASUS-TIMI 54 study, a large scale outcomes trial involving over 21,000 patients, successfully met its primary efficacy endpoint. The study assessed BRILINTA® (ticagrelor) tablets at either 60mg twice daily or 90mg twice daily plus low-dose aspirin for the secondary prevention of atherothrombotic events in patients who had experienced a heart attack one to three years prior to study start. The primary efficacy endpoint was a composite of cardiovascular (CV) death, myocardial infarction (MI) or stroke.. Preliminary analysis did not reveal any unexpected safety issues. Full evaluation of data is ongoing.. Elisabeth Björk, Vice President, Head of Cardiovascular and Metabolic Diseases, Global Medicines Development, AstraZeneca,said: "We are very pleased with the top line results of the PEGASUS-TIMI 54 study, the second positive major outcomes study in the PARTHENON programme. The results build on existing understanding of the benefits of BRILINTA for patients ...
If the amount of sunlight is greater on one side of the plant, the phototropins trigger reactions that will cause the redistribution of auxin by efflux pumps to the dark side of the plant. High concentrations of auxins cause cells on the shaded side of the cell to swell and elongate. When auxin binds to a receptor in the nucleus , this activates a proton pump. The proton pump moves H+ ions into spaces in the cell wall, decreasing the pH. This results in the breaking of the hydrogen bonds between cellulose fibres, resulting in the swelling and elongation of these cells. As the cells elongate and swell on one side of the plant the stem starts to curve towards the light source because of this uneven growth. The plant now is growing towards the light source (phototropism ...
Some of the earliest research on hormones involved plants. In the 1870s, English naturalist Charles Darwin (1809-1882) and his son Francis (1848-1925) studied the effect of light on plant growth. They discovered that plants tend to grow towards a source of light. They called the process phototropism. The reason for this effect was not discovered for another half century. Then, in the 1920s, Dutch-American botanist Frits Went (1863-1935) discovered the presence of certain compounds that control the growth of plant tips toward light. Went named those compounds auxins. Auxins are formed in the green tips of growing plants, in root tips, and on the shaded side of growing shoots. They alter the rate at which various cells in the plant grow so that it always bends towards the light. ...
What is a stream of consciousness? This presupposes that one knows what consciousness is, and how it differs from the unconscious, and from self-consciousness. Briefly, consciousness means an awareness of something, most broadly your environment. In this sense, even plants are conscious, as shown by the phenomenon of phototropism. Self-consciousness, by contrast, denotes not just…. ...
To Show That Starch Is Made During Photosynthesis, Conditions Necessary for Germination of Seeds, Phototropism, Diffusion, osmosis
When teaching phototropism or any other reason to grow plants from seeds, this can be linked to the reuse of everyday items which would normally be disposed of. For example the plastic trays which mushrooms come in can be used to hold the compost (addition of some holes to allow drainage will be needed). Similarly the…
Phototropins are photoreceptor proteins (more specifically, flavoproteins) that mediate phototropism responses in higher plants. Along with cryptochromes and phytochromes they allow plants to respond and alter their growth in response to the light environment. Phototropins may also be important for the opening of stomata[citation needed] and the movement of chloroplasts. Phototropins are part of the phototropic sensory system in plants that causes various environmental responses in plants. Phototropins specifically will cause stems to bend towards light[citation needed] and stomata to open.[citation needed] Phototropins have been shown to impact the movement of chloroplast inside the cell. In addition phototropins mediate the first changes in stem elongation in blue light prior to cryptochrome activation. Phototropin is also required for blue light mediated transcript destabilization of specific mRNAs in the cell.[citation needed] Wada M, Kagawa T, Sato Y (2003). "Chloroplast movement". Annu Rev ...
Phototropins are plasma membrane-localized UVA/blue light photoreceptors which mediate phototropism, inhibition of primary hypocotyl elongation, leaf positioning, chloroplast movements, and stomatal opening. Blue light irradiation activates the C-terminal serine/threonine kinase domain of phototropin which autophosphorylates the receptor. Arabidopsis thaliana encodes two phototropins, phot1 and phot2. In response to blue light, phot1 moves from the plasma membrane into the cytosol and phot2 translocates to the Golgi complex. In this study the molecular mechanism and route of blue-light-induced phot2 trafficking are demonstrated. It is shown that Atphot2 behaves in a similar manner when expressed transiently under 35S or its native promoter. The phot2 kinase domain but not blue-light-mediated autophosphorylation is required for the receptor translocation. Using co-localization and western blotting, the receptor was shown to move from the cytoplasm to the Golgi complex, and then to the post-Golgi ...
At present, it is generally accepted that the phototropic response to blue light initiates a lateral auxin gradient within the stem. Although several components for stimulus perception and signal transduction have been identified (Kimura and Kagawa, 2006; Christie, 2007; Harada and Shimazaki, 2007), it is only partially clear on the molecular level how lateral blue light irradiation leads to a bending response toward the illuminated side of the stem and how gravity is influencing this process. Several lines of evidence indicate that PINFORMED1 (PIN1) and PIN3 redistribution plays a key role in this tropic response (Friml et al., 2002a, 2002b; Blakeslee et al., 2004). However, a clear picture of how phototropin-mediated light perception is connected to PIN1/3 redistribution is still elusive. Additionally, little is known about signaling elements beyond NPH3 and RPT2 connecting phototropin light perception physically to auxin redistribution. Meanwhile, several proteins directly binding to NPH3 ...
We are thrilled to announce a 7 week old baby. Yes, this is a very early announcement. But it is significant because we have passed our two previous losses and believe we are now out of the troublesome time. Heres a recap on our baby journey.. July 27 2013 - On our first anniversary I had my first positive pregnancy test. August 2013 - at an 8 week ultrasound we discovered the baby stopped developing at 6.5 weeks. September 3, 2013 - induced miscarriage (mini-labor) via Cytotec after waiting 2 weeks since development ended. He was named Ezekiel (God strengthens).. March 2014 - first baby wouldve been born. May 11 2014 - Mothers Day. I was entirely unprepared for how this day would hit me.. May 2014 - after many months of irregular schedules and no successful pregnancy yet, we are tested for preliminary fertility concerns. July 4 2014 - second positive pregnancy test. July 27 2014 - pregnant again during our anniversary. No adult beverages while out to supper. Noticing a trend here.. August 8 ...
DETROIT -- Royals infielder Miguel Tejadas season and possibly his playing career are over after he was suspended 105 games without pay upon testing positive for an amphetamine in violation of Major League Baseballs Joint Drug and Prevention Program.. MLB announced the suspension, which is effectively immediately, on Saturday afternoon.. Tejada issued an apology through the Major League Baseball Players Association, and Royals players expressed surprise and praised him as a good teammate.. Yahoo! Sports Jeff Passan reported that because Tejada had tested positive under MLBs amphetamine policy earlier in his career, he was subject to a 25-game ban for a second positive, found in a test this season. A third positive test followed and called for an additional 80-game suspension, totaling 105 games.. The 105-game suspension is the third-longest ever levied by MLB, behind the 211-game penalty Alex Rodriguez is currently appealing and Steve Howes 119-game ban in 1992. With 41 games remaining this ...
Almost all our food, feed, fuel and fiber ultimately derive from plants. Plant growth depends on photosynthesis, the process in which light energy is harnessed for the synthesis of high-energy carbon compounds. In order to capture light, plants have evolved unique ways of building cells, tissues and organs, a highly diverse metabolism, and a life-long continuation of versatile growth and development. Plants possess numerous photoreceptors enabling them to sense changes in the amount, spectral composition (color), photoperiod and direction of light. The central goal of our research is to understand how plants manage to gain access to direct sunlight when this resource becomes limiting. This occurs at high plant density leading to specific growth and developmental strategies such as the Shade Avoidance Syndrome (SAS) and Phototropism. We use the model plant Arabidopsis thaliana to study the molecular events leading from light perception to the physiological responses elicited by unfavorable light ...
Something a little different than Arabidopsis; in fact, not a plant at all: Fungal Photobiology. I am looking for a highly motivated postdoctoral scientist with experience in plant photobiology, plant development, and transcriptome profiling to lead a newly funded project in fungal photomorphogenesis. This is an excellent opportunity to apply what you have learned from Arabidopsis biology to a new biological system with immense potential for novel biological discoveries. Postdoctoral Researcher in Photomorphogenesis University of Florida Laboratory of Jeffrey A. Rollins A postdoctoral research position is available to identify and characterize global regulators of fungal fruiting body (apothecia) development in response to light. The incumbent will be responsible for two specific experimental objectives: 1) Characterize the fluence-response of stipe de-etiolation to establish with high temporal resolution the onset of the developmental transition from stipe to disc. 2) Identify and characterize, ...
Cryptochromes, Cry, are photoreceptors that absorb blue light and mediate signaling events to modulate a wide range of biological functions such as circadian entrainment and phototropism. The signaling activation is triggered by excitation of the flavin adenine dinucleotide cofactor, followed by protein conformational changes that mediate protein-protein interaction with downstream partners. In this presentation, I will discuss the conditions and functional dynamics of drosophila cryptochrome through a plethora of molecular dynamics simulation and analysis tools. Our model recapitulates various experimental evidence of dCry activation, and the mechanism may be applicable to other cryptochromes.. ...
Post-Doctoral Position,br, Arabidopsis Signal Transduction,br, A post-doctoral position is available immediately in the laboratory of Mannie Liscum at the University of Missouri-Columbia.  This project deals with the reverse genetic analyses of the ,i,NPH3,/i,/,i,RPT2,/i, gene family in Arabidopsis.  This large family of genes (>15 members) encode novel proteins, however both NPH3 and RPT2 have been shown genetically to be required for early signal transduction during response to phototropic stimuli.  We hypothesize that this novel family of proteins function as molecular scaffolds to mediate the assembly/stability of signal transduction components in a variety of signal-response systems (i.e., not limited to phototropism).  A variety of approaches will be used address the biological roles of members of this family, including isolation of knock-out mutants via T-DNA and transposon mutagenesis, generation of mutants through anti-sense construction, and transgenic ...
Review: Harnessing synthetic chemistry to probe and hijack auxin signaling Auxin has been studied since Charles Darwin observed the phototropic response.
The carotenoids are not only amongst the most widespread of the naturally occurring groups of pigments, but probably also have the most varied functions; witness their known roles in photokinetic responses of plants, in phototropic responses of fish and as vitamin A precursors in mammals and birds. Pigments with such wide distribution and such diverse functions are obviously of great interest to biological scientists with very different specializa tions, especially as it is unlikely that the study of the functions of carotenoids is anywhere near complete. The primary aim of the present work is to discuss the distribution, bio genesis and function of the carotenoids throughout the plant and animal kingdoms in such a way that, because of, rather than in spite of its bio chemical bias, it will be of value to workers interested in all the biological aspects of these pigments. The biochemical approach is considered the most effective because, generally speaking, most progress in the study of ...
Plants can sense the Earths gravitational field. Geotropism is the term applied to the consequent orientation response of growing plant parts. Roots are positively geotropic, that is, they will bend and grow downwards, towards the center of the Earth. In contrast, shoots are negatively geotropic, that is, they will bend and grow upwards, or away, from the surface.. These geotropisms can be demonstrated easily with seedlings grown entirely in darkness. A seedling with its radicle (or seedling root) and shoot already in the expected orientation can be turned upside down, or placed on its side, while kept in darkness. The root will subsequently bend and grow downwards, and the shoot upwards. Because the plant is still in darkness, phototropism (a growth movement in response to light) can be eliminated as an explanation for these movements.. Several theories about the manner by which plants perceive gravity have been advanced, but none of them is entirely satisfactory. To account for the positive ...
7.7. Mean values of total bacterial counts were generally less than 105 CFU/g except for brand "F" which contained about 103 CFU/g. Wide variation in the percentage of sporeformers in total count was observed. Mean values of spore counts ranged from 103 to 104 CFU/g. Bacillus cereus was found in variable densities; mean values hardly exceeding 104/g, it was not detected in some samples. Generally, B. Cereus represented 20-70% of the total spore counts. Yeast colony mean counts around 102 CFU/g. Enterobacteriaceae, molds coliforms, Staphylococcus aureus, Streptococcus faecalis and salmonellae could not be detected in all samples. D10 value of B. cereus was 2.85 KGy, while the D10 values at 85, 90, 95 and 100C were found to be 15.0, 9.5, 8.5 and 2.5 min, respectively. Preirradiation treatment of B. cereus spores had a synergistic effect with heat treatment ...
Electrocompetent Top10 cells were electroporated with K238015, K238013 in psB3K3, I20260 and empty Top10 cells. These cells were plated out on agar plates with the correct AntiBiotic and grown overnight (37°). From these, a 5ml liquid culture supplied with AB was prepared and also grown overnight (37°C or 25°C). These cells were inoculated in fresh LB medium (100 µg AB/ ml) in the morning and grown at 16°C or 25°C for 3.5h. During all these steps, the cells were always kept away in the dark. Only when the experiment started, half of the cultures were put under blue light, the other half were kept in the dark. After that, the cells were whithdrawn at different time intervals. They were diluted into PBS and analyzed by flow cytometry with a Becton Dickinson FACSCalibur and CELLQuestTM acquisition and analysis software with gates set to forward and side scatters characteristic of the bacteria (Gate G2=R2). We decided upon using FACS because then the fluorescence of single cells is measured. ...
1. Find the area of the region bounded by the curves and lines y=e^x sin e^x, x=0, y=0, and the curves first positive intersection with the x-axis. 2. The area under the curve of y=1/x from x=a to x=5 is approximately 0.916 where ...
States Trace Back Finds Second Positive CWD in Herd Directly Linked to Index Herd A second positive case of chronic wasting disease (CWD) in New York State has been confirmed in a white-tailed deer from a captive herd in Oneida County that is directly linked to the herd where a white-tailed doe was found positive for CWD earlier this week. CWD is a transmissible disease that affects the brain and central nervous system of deer and elk. There is no evidence that CWD is linked to disease in humans or domestic livestock other than deer and elk.. During the investigation of the States first case of CWD this week, the New York State Department of Agriculture and Markets found that one of the herds associated with the index animal had recently sent a sample to the States Veterinary Diagnostic Laboratory to be tested for CWD. The sample was collected and sent for testing as part of the States mandatory CWD surveillance and testing protocols.. The positive sample was from a four to five year old ...
Phototropins are UVA/blue-light receptors involved in controlling the light-dependent physiological responses which serve to optimize the photosynthetic activity of plants and promote growth. The phototropin-induced phosphoinositide (PI) metabolism has been shown to be essential for stomatal opening and phototropism. However, the role of PIs in phototropin-induced chloroplast movements remains poorly understood. The aim of this work is to determine which PI species are involved in the control of chloroplast movements in Arabidopsis and the nature of their involvement. We present the effects of the inactivation of phospholipase C (PLC), PI3-kinase (PI3K) and PI4-kinase (PI4K) on chloroplast relocations in Arabidopsis. The inhibition of the phosphatidylinositol 4,5-bisphospahte [PI(4,5)P2]-PLC pathway, using neomycin and U73122, suppressed the phot2-mediated chloroplast accumulation and avoidance responses, without affecting movement responses controlled by phot1. On the other hand, PI3K and PI4K ...
Orioles left-hander Troy Patton was issued a 25-game suspension by the Commissioners Office on Friday for violating Major League Baseballs Joint Drug Prevention and Treatment Program.. Patton, 28, tested positive for an amphetamine in violation of the program. His suspension begins at the start of the 2014 season.. According to The Associated Press, Patton told The Baltimore Sun he took an Adderall pill four days before the season finished to try to improve his short-term focus.. Under the Joint Drug agreement, 25 games is the penalty for a second positive amphetamine test. A first positive results in evaluation and further testing.. According to The Sun, Patton tested positive for amphetamine use during Spring Training in 2010, also for Adderall.. "We were disappointed to learn of Troy Pattons suspension," Orioles executive vice president of baseball operations Dan Duquette said Friday. "The Orioles support MLBs policy and its efforts to eliminate performance-enhancing substances from the ...
Organisms have evolved extensive sensory mechanisms to perceive information carried by light. Their responses are mediated by photoreceptor proteins, which are sensitive to light through prosthetic chromophore molecules. The past decade has witnessed the discovery of a large number of novel flavin-binding photoreceptors, notably the phototropins, the cryptochromes, and BLUF (blue-light sensing using FAD) domains (1). Phototropins are primarily found in plants and control several physiological responses such as phototropism, chloroplast movement, and stomatal opening (2), whereas cryptochromes are known to regulate growth and development in plants and circadian rhythms in plants and insects (3, 4). BLUF domains are a distinct family of flavin-binding photoreceptors that show no significant relationship to other sensor proteins in sequence or structure. The BLUF domain was first discovered as the N-terminal part of the flavoprotein AppA from the purple photosynthetic bacterium Rhodobacter ...
Blue light is of course a main contributor to photosynthesis via chlorophyll, but it also influences a plant in other ways. Blue light is typically encountered in nature at midday, when the angle of the sun is directly vertical or close to it. This would usually be a time of peak intensity and heat, therefore in many plants high intensities of blue light cause the chlorophylls to migrate to the bottom of the cell for shielding. Moreover, cryptochrome is a phytochemical that absorbs the blue spectrum and initiates phototropism (growing towards light), plus sets a plants circadian rhythm (in combination with phytochrome and the photoperiod). Interestingly, strong blue light reduces leaf intermodal length in a plant and causes it to grow compact and bushy, not wasting energy on stem length, which would be unnecessary in blue dominant full sun conditions. Many growers use blue light to keep plants compact and under control. In addition plant stomata number increases with the intensity of the blue ...
Colony formation was the first step towards evolution of multicellularity in many macroscopic organisms. Dictyostelid social amoebas have used this strategy for over 600 Myr to form fruiting structures of increasing complexity. To understand in which order multicellular complexity evolved, we measured 24 phenotypic characters over 99 dictyostelid species. Using phylogenetic comparative methods, we show that the last common ancestor (LCA) of Dictyostelia probably erected small fruiting structures directly from aggregates. It secreted cAMP to coordinate fruiting body morphogenesis, and another compound to mediate aggregation. This phenotype persisted up to the LCAs of three of the four major groups of Dictyostelia. The group 4 LCA co-opted cAMP for aggregation and evolved much larger fruiting structures. However, it lost encystation, the survival strategy of solitary amoebas that is retained by many species in groups 1-3. Large structures, phototropism and a migrating intermediate slug stage ...
The sample that tested positive was collected Aug. 16, the health department said. It was the first positive sample in Suffolk County since 2008.
blue light on sony kdf42we655 model lcd projection tv I am told it is the light engine - Sony Grand WEGA KDF-60WF655 60 question
TY - JOUR. T1 - Blue-Light- and Phosphorylation-Dependent Binding of a 14-3-3 Protein to Phototropins in Stomatal Guard Cells of Broad Bean. AU - Kinoshita, Toshinori. AU - Emi, Takashi. AU - Tominaga, Misumi. AU - Sakamoto, Koji. AU - Shigenaga, Ayako. AU - Doi, Michio. AU - Shimazaki, Ken Ichiro. PY - 2003/12/1. Y1 - 2003/12/1. N2 - Phototropins are blue-light (BL) receptor serine (Ser)/threonine kinases, and contain two light, oxygen, and voltage (LOV) domains, and are members of the PAS domain superfamily. They mediate phototropism, chloroplast movement, leaf expansion, and stomatal opening of higher plants in response to BL. In stomatal guard cells, genetic analysis has revealed that phototropins mediate activation of the plasma membrane H+-ATPase by phosphorylation and drive stomatal opening. However, biochemical evidence for the involvement of phototropins in the BL response of stomata is lacking. Using guard cell protoplasts, we showed that broad bean (Vicia faba) phototropins (Vfphots) ...
The New York State Department of Environmental Conservation today announced that it has received the remainder of test results for chronic wasting disease (CWD) that were part of intensive sampling efforts in central New York. DEC has received two positive results for the disease out of 292 wild deer sampled.. The first positive result in a wild deer was announced on April 27, 2005 and came from a yearling white-tailed deer sampled from the Town of Verona, Oneida County. The second positive result is from a 3-year-old doe, located within a mile of the location where the initial positive result was detected. The sample tissues were tested at the States Veterinary Diagnostic Laboratory at Cornell University. These are the first known occurrences of CWD in wild deer in New York State.. DEC implemented intensive monitoring efforts after CWD was found in two captive white-tailed deer herds in Oneida County - the first incidents of CWD in New York State. On April 8, 2005, the State Department of ...
Gilroy S, Masson P (Eds.). Plant Tropisms. Ames, Iowa: Blackwell Publishing, 240 pp., October 2007. (PIs: S. Gilroy, P. Masson) Note: Most chapters in this book are authored by current or former PIs. The chapters are: (1) Valster AH, Blancaflor EB. Mechanisms of gravity perception in higher plants; (2) Harrison BR, Morita MT, Masson PH, Tasaka M. Signal transduction in gravitropism; (3) Muday GK, Rahman A. Auxin transport and the integration of gravitropic growth; (4) Mullen JL, Kiss JZ. Phototropism and its relationship to gravitropism; (5) Monshausen GB, Swanson SJ, Gilroy S. Touch sensing and thigmotropism; (6) Cassab GI. Other tropisms and their relationship to gravitropism; (7) Braun M, Hemmersbach R. Single-cell gravitropism and gravitaxis; (8) Correll MJ, Kiss JZ. Space-based research on plant tropisms; (9) Brown CS, Sederoff HW, Davies E, Ferl RJ, Stankovic B. Plan(t)s for space exploration. ...
The composite data from eight subjects exposed to eight irradiances of narrowband blue LED light demonstrated increased melatonin suppression with increased exposure irradiance. Those data have a strong fit to a sigmoidal fluence-response curve. A comparison of mean melatonin suppression with 40 μW/cm2 from 4,000 K broadband white fluorescent light, currently used in most general lighting fixtures, suggests that narrow bandwidth blue LED light may be stronger than 4,000 K white fluorescent light for suppressing melatonin.. An initial action spectrum study on mice first identified peak sensitivity to light for circadian regulation in the short-wavelength portion of the spectrum, specifically at 480 nm (60). Later action spectra studies demonstrated that the blue-appearing portion (446-477 nm) was the most effective region of the spectrum for suppression of melatonin secretion from the pineal gland in humans (10, 57). Recent analytic action spectra have examined neuroendocrine, circadian, and ...
Protein photosensors are versatile tools for studying ligand-regulated allostery and signaling. Fundamental to these processes is the amount of energy that can be provided by a photosensor to control downstream signaling events. Such regulation is exemplified by the phototropins--plant serine/threonine kinases that are activated by blue light via conserved LOV (light, oxygen and voltage) domains. The core photosensor of oat phototropin 1 is a LOV domain that interacts in a light-dependent fashion with an adjacent alpha-helix (J alpha) to control kinase activity. We used solution NMR measurements to quantify the free energy of the LOV domain-J alpha-helix binding equilibrium in the dark and lit states. These data indicate that light shifts this equilibrium by approximately 3.8 kcal mol(-1), thus quantifying the energy available through LOV-J alpha for light-driven allosteric regulation. This study provides insight into the energetics of light sensing by phototropins and benchmark values for ...
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In a message dated 11/10/02 10:09:13 PM Pacific Standard Time, email @ redacted writes: , Maybe it was just too long a time. Granted that NPH was a vast improvement , over Protamine Zinc, but I feel that over time (34 years) NPH does not stay , with its pattern, and that doctors relied too heavily on that supposed , "set , pattern of activity" that NPH was supposed to provide. I "curse" the NPH , for the hypos it put me into, with no "pattern" other than to expect the , unexpected. To me, it was the "demon" insulin. ]:,, , , George George I agree 100%! The part of hypos on NPH that I had trouble with was it snuck up on you a little bit at a time. If it was a Reg hypo you would crash fast. On NPH it would creep up and before you knew it you were in trouble. I may be wrong, but I think my unawareness was due to the slow decline of BS levels from NPH. YMMV Roger C ---------------------------------------------------------- for HELP or to subscribe/unsubscribe, contact: [email protected] send ...
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Tumors on liver have finally responded favorably from chemo. Shrank more than half there size. All other is stable. First positive news in a long time. Actually when I was told I was so surprised I got good news I didnt even react. I was in disbelief but very happy. I know I cant be cured but cherish any extra time to be with my family.. ...
As Im sure was the case with many others, I used to use the insulin NPH when I was first diagnosed. I was extremely careful and diligent back then, perhaps ...
Here, we show that the Neurospora protein VVD is a blue light photoreceptor. Following the heterologous expression in E.coli, VVD was found to be associated with a flavin‐type chromophore (Figure 3). Upon illumination, the native VVD protein underwent a blue light‐induced absorbance change that was fully reversible in the dark (Figure 4). This photocycle was also reported for the LOV domains of the plant blue light photoreceptor phototropin and indicates the formation of a reversible covalent bond between the conserved cysteine in the VVD LOV domain and the flavin chromophore (Briggs and Christie, 2002). The formation of the cysteinyl‐flavin adduct results in subtle structural changes of the flavin‐binding pocket (Crosson and Moffat, 2002). The latter changes are thought to represent the initial event in light signal transduction and seem to lead to the activation of the intra‐molecular kinase in phototropins. However, VVD is different in this respect since it only contains the LOV ...
TABLE-US-00001 TABLE 1 Polymerization IBOA Adamantyl Polyfunctional initiator Resin (wt %) acrylate acrylate IRGACURE 369 Example 1 A 85 MADA 6 wt % TMPTA 5 wt % 4 wt % Example 2 B 90 MADA 3 wt % TMPTA 5 wt % 2 wt % Comparative C 90 -- TMPTA 6 wt % 4 wt % Example 1 Example 3 D 85 EADA 5 wt % TMPTA 7 wt % 3 wt % Example 4 E 90 EADA 2 wt % TMPTA 5 wt % 3 wt % Comparative F 92 -- PBFA 5 wt % 3 wt % Example 2 Example 5 G 90 EADA 2 wt % PBFA 5 wt % 3 wt % Example 6 H 90 ADDA 2 wt % TMPTA 5 wt % 3 wt % Example 7 I 87 ADDA 4 wt % EGTA9 6 wt % 3 wt % Example 8 J 90 ADDA 3 wt % PBFA 4 wt % 3 wt % Example 9 K 85 MADA 8 wt % DTMPTA 4 wt % 3 wt % Example 10 L 80 MADA 8 wt % TMPTA 8 wt % 4 wt % Example 11 M 95 MADA 2 wt % TMPTA 2 wt % 1 wt % Example 12 N 78 MADA 10 wt % TMPTA 10 wt % 2 wt % Example 13 O 97 MADA 1 wt % TMPTA 1 wt % 1 wt % Example 14 P 90 MADA 1 wt % TMPTA 5 wt % 3 wt % Example 15 Q 80 MADA 15 wt % TMPTA 3 wt % 2 wt % Example 16 R 90.2 MADA 0.8 wt % TMPTA 5 wt % 3 wt % Example 17 S 80 MADA 17 ...
Your eyes are sensitive to a narrow band of frequencies referred to as the, "visible light spectrum." Visible light-light capable of being seen by the human eye -consists of wavelengths of varying lengths.. Blue light has a very short wavelength and is detectable by the human eye. Not only does it provide basic illumination to our worlds, blue light also helps to increase feelings of well-being. But exposure to large amounts of blue light can be harmful to the eyes.. The plethora of electronic devices in use today, such as cell phones, tablets, and laptop computers, has drastically increased our exposure to blue light. Another source of blue light is energy efficient technology in the form of fluorescent light bulbs and LED lights. Research has determined that the lens inside the eye, and the pigment in the back of the eye, offer some protection against blue light. But this protective mechanism only lasts for short period of exposure to the intense blue light, and during daylight hours.. Perhaps ...
This species hides in leaf litter or among rocks or logs in forests. It typically occurs at low densities, and is most often found in damp, rich habitats, often on lower forest slopes with coarse woody debris. It is especially fond of rotten sugar maple logs, but is found in a variety of damp forest and forest-edge habitats. In some cases it may be found in grassy areas such as roadsides (Hubricht, 1985). In a field study of N. albolabris distribution in an Ohio hardwood forest, this animal was found near larger rocks and was most active in periods of warmer temperatures and rainfall (Emberton, 1980). A field experiment in Michigan discovered that young N. albolabris had slower growth rates in the presence of adults, due to competition for food or water (Pearce, 1997). In a beech-hemlock stand in New York, Calosoma sp. beetles were a common predator of this snail (Ingram, 1950). Taxonomy ...
Get an answer for Can a x-ray goggle be mada at home by using polarized lens, glycerol, other colourfull lens and a lazer light? and find homework help for other questions at eNotes
So whats the deal with blue light? And what has changed about the artificial light we experience every day? Read on to find out more about the good and the bad of blue light. Why do our bodies need the biological effects of this wavelength? And how and when should we protect ourselves from the potentially damaging effects of blue light?
95% of Americans are in the habit of using LED screens at least one hour before bedtime. The blue light emitted by these devices interferes with sound sleep at night. This post from Popular Science describes a neuroscientists experiment with blue light blocking glasses in a bid to block the blue light and improve the quality of sleep. I recently wrote about the terrible sleep ... Continue Reading ...
The molecular basis of shade avoidance reaction PNAS report on a collaborative study involving RUB scientists Plants that lose the battle during competitiveness for light because they are shaded by larger neighbours, counteract. They adapt by rapid shoot elongation and stretch their leaves towards the sun. The molecular basis of this so-called shade avoidance syndrome had been unclarified to date. Research scientists from the Utrecht University in the Netherlands and the Ruhr University in Bochum have now been able to unravel a regulation pathway.
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Wholeasale and retail Blue Lights For Car now available from LightInTheBox.com! LightInTheBox.com is your source for quality wedding supplies at wholesale prices.
From your cell phone to your laptop, exposure to blue light can affect our health, from sleep to mood. Here is everything you need to know.
Blue light is simply a kind of light that is produced by many electronic devices. The more we learn about blue light, the more we are made aware of how it affects our body, and what we can do to stop these negative effects. Healthversed has put together this handy guide to introduce you to exactly what blue light is and how you can stop it from taking a toll on your health. ...
Amaç: Bu çalışmada, basit horlama veya hafif derecede obstrüktif uyku apnesi (OUA) bulunan hastalarda yumuşak damağa radyofrekans doku ablasyonu (RFDA) uygulamasının erken dönemde horlama şiddeti, apne indeksi ve gündüz uykululuk haline etkileri değerlendirildi. Hastalar ve Yöntemler: Çalışmaya apnesiz basit horlaması olan 61, apne indeksi (Aİ) ≤5 ile basit horlaması olan 13 ve hafif derecede OUA (5 ...
Doç.Dr., Ankara Üniversitesi Tıp Fakültesi Göz Hastalıkları Anabilim Dalı. Patolojik miyopide görme azalmasının en önemli nedeni, eksudatif veya ilerleyici atrofik makula dejenerasyonudur. Bu çalışmada farklı görünümde makula lezyonu olan yüksek miyopili bir olgu, flöresein anjiografi ve optik koherens tomografi bulguları ile tartışılmıştır. Keywords : Patolojik miyopi, makula tutulumu, flöresein anjiografi, optik koherens tomografi ...
Photodynamic therapy (PDT) of the thoracic cavity can be performed in conjunction with surgery to treat cancers of the lung and its pleura. However, illumination of the cavity results in tissue exposure to a broad range of fluence rates. In a murine model of intrathoracic PDT, we studied the efficacy of 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH; Photochlor®)-mediated PDT in reducing the burden of non-small cell lung cancer for treatments performed at different incident fluence rates (75 versus 150 mW/cm). To better understand a role for growth factor signaling in disease progression after intrathoracic PDT, the expression and activation of epidermal growth factor receptor (EGFR) was evaluated in areas of post-treatment proliferation. The low fluence rate of 75 mW/cm produced the largest reductions in tumor burden. Bioluminescent imaging and histological staining for cell proliferation (anti-Ki-67) identified areas of disease progression at both fluence rates after PDT. However, increased
The circadian and neurobehavioral effects of light are primarily mediated by a retinal ganglion cell photoreceptor in the mammalian eye containing the photopigment melanopsin. Nine action spectrum studies using rodents, monkeys, and humans for these responses indicate peak sensitivities in the blue region of the visible spectrum ranging from 459 to 484 nm, with some disagreement in short-wavelength sensitivity of the spectrum. The aim of this work was to quantify the sensitivity of human volunteers to monochromatic 420-nm light for plasma melatonin suppression. Adult female (n=14) and male (n=12) subjects participated in 2 studies, each employing a within-subjects design. In a fluence-response study, subjects (n=8) were tested with 8 light irradiances at 420 nm ranging over a 4-log unit photon density range of 10(10) to 10(14) photons/cm(2)/sec and 1 dark exposure control night. In the other study, subjects (n=18) completed an experiment comparing melatonin suppression with equal photon doses (1.21 x 10
Phase 1 , Phase 2 , Poule des As Phase 1 Vondrona A , Vondrona B , Vondrona C , Vondrona D Vondrona A [at Mahajanga] Round 1 [Aug 12] TAM Port Berger 1-3 RTS-Jet Mada SOM-Fosa Juniors FC 8-0 Espoir Manerinerina USSK Ambanja 0-2 FC Joel Round 2 [Aug 14] FC Joel 5-0 Espoir Manerinerina USSK Ambanja 2-1 TAM Port Berger SOM-Fosa Juniors FC 1-3 RTS-Jet Mada Round 3 [Aug 17] FC Joel 2-1 RTS-Jet Mada USSK Ambanja 4-1 Espoir Manerinerina SOM-Fosa Juniors FC 11-1 TAM Port Berger Round 4 [Aug 19] SOM-Fosa Juniors FC 4-0 USSK Ambanja FC Joel 5-2 TAM Port Berger Espoir Manerinerina 0-3 RTS-Jet Mada Round 5 [Aug 21] Espoir Manerinerina 0-4 TAM Port Berger USSK Ambanja 4-4 RTS-Jet Mada SOM-Fosa Juniors FC 2-0 FC Joel Final Table: 1.SOM-Fosa Juniors FC (Boeny) 5 4 0 1 26- 4 12 Qualified 2.FC Joel (Sava) 5 4 0 1 14- 5 12 Qualified 3.RTS-Jet Mada (Itasy) 5 3 1 1 14- 8 10 Qualified - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 4.USSK Ambanja (Diana) 5 2 1 2 10-12 7 5.TAM Port Berger (Sofia) 5 1 ...
Spermatik kord inguino-skrotal bölge ameliyatlarında dikkat edilmesi gereken en önemli inguinal yapıdır. Cerrahi olarak spermatik kord ve elemanlarına uygulanan hasarların testiküler hasara ve sonuç olarak infertiliteye neden olduğu bilinmektedir. Bu çalıĢmada, ratlarda vas deferenste oluĢturulan hasar tiplerinin; vas deferens, testis ve epididim üzerinde oluĢturduğu etkilerin irdelenmesi amaçlanmıĢtır. ÇalıĢmada kullanılan 34 adet prepubertal erkek Sprague Dawley rat; digital kompresyon, traksiyon, kesi ve kontrol grupları olmak üzere 4 gruba ayrıldı. Digital kompresyon grubunda sağ vas deferens serbestleĢtirilerek ılık ıslak spanç ile iki parmak arasında 4 dakika basınç uygulandı. Traksiyon grubunda sağ vas deferens serbestleĢtirildikten sonra askıya alınarak 10 gr ağırlık ile 4 dakika traksiyon uygulandı. Kontrol grubunda cerrahi model uygulanmadı, sadece vas deferens ve testis varlığı görüldü. Kesi grubunda ise sağ vas deferens ...
Prva vrsta koja nije pronađena u škriljcu formacije Niobarara, Hesperornis altus, živjela je prije oko 78 milijuna godina u Montani, a poznata je iz nepotpunog donjeg dijela noge; pronađena je u formaciji Judith River. Mada ju je Marsh isprva svrstao u novi rod Coniornis, to se desilo zbog njegovog mišljenja da je Hesperornis postojao samo u Kansasu, pa bi po toj logici bilo koja vrsta iz Montane trebala biti svrstana u drugi rod. Većina kasnijih istraživača nije se složila sa ovime, pa su svrstali Coniornis altus u isti rod kao i Hesperornis, i to kao H. altus.[14][15] U Claggett Shaleu u Montani je pronađena još jedna vrsta. Vrsti H. montana je naziv 1915. godine dao Shufeldt, i mada se njen jedini poznati ostatak (jedan leđni kralježak) ne može direktno usporediti sa H. altus, Shufeldt i ostali smatraju je odvojenom vrstom zato što je manja.[16]. Nessov i Yarkov su 1993. godine prve ostatke roda Hesperornis pronađene izvan Sjeverne Amerike priznali kao novu vrstu. Dali su joj ...
But some opposition leaders, balking at the internal power play displayed by Renzi, asked Napolitano to have Parliament take up the matter so Renzis Democrats are forced to explain in public why they ousted their own leader.. The 39-year-old Renzi rallied his partys executives Thursday to back him in an internal vote of no-confidence against Letta, accusing him of failing to lift Italy out of its economic and political doldrums.. The timing of the ouster was ironic given that national statistics bureau Istat reported Friday that fourth-quarter GDP edged up 0.1 percent, the first positive growth since mid-2011.. Renzis maneuver was stunning even by Italian political standards, since he had long insisted that he would only gun for the premiership via an election and the popular mandate that would give him. But analysts said he clearly saw an opportunity and seized it, even though the risks of it failing are high.. "Enrico Letta was not a bad prime minister, but he was not seen as getting things ...
We received our first positive culture for Pseudomonas, it felt surreal having dreaded that culture for 5 years now. Part of me feels like I should go cleaning crazy around our house and replace everything, but I know logically that it is every where and it was only a matter of time.You can read more […]. ...
USD 23.54 Only, Buy D1S 10000K 35W HID Xenon Car Light Bulbs Blue Light with Worldwide Free Shipping for All Orders at Tmart.com.
Hugeverf i van Dorp su prvi izolovali izohinolin iz ugljene smole 1885. godine. Oni su ga izolovali frakcionom kristalizacijom kiselog sulfata. Veisgerber je razvio brži metod 1914 putem selektivne ekstrakcije smole, koristeći činjenicu da je izohinolin bazniji od hinolina.. Mada se derivati izohinolina mogu sintetisati na nekoliko načina, relativno mali broj direktnih metoda proizvodi nesupstituisani izohinolin. Pomeranz-Fritschova reakcija je efikasan metod za pripremu izohinolina. Ta reakcija koristi benzaldehid i aminoacetoaldehid dietil acetal, koji u kiselom medijumu reaguju da formiraju izohinolin. Alternativno, benzilamin i glioksal acetal se mogu koristiti, do bi se ostvario isti rezultat.. ...
İntrakranial lipomlar, oldukça ender görülen konjenital beyin malformasyonları olup genellikle asemptomatiktirler. Bununla beraber lokalizasyonuna göre klinik belirti verebilirler. Sıklıkla intrakranial olarak orta hatta veya orta hatta yakın yerleşirler. Bu çalışmada, başağrısı şikayeti ile başvuran ve tuber cinereum lipomu tanısı alan bir hastanın manyetik rezonans görüntüleme bulguları sunulmaktadır.
Type 2 diabetes develops during the course of a persons lifetime. It is the type that used to be called adult-onset diabetes, though that term
Plants in dense vegetation compete for resources and detect competitors through reflection of far-red (FR) light from surrounding plants. This reflection causes a reduced red(R):FR ratio, which is sensed through phytochromes. Low R:FR induces shade avoidance responses of the shoot and also changes the root system architecture, although this has received little attention so far. Here we investigate the molecular mechanisms through which light detection in the shoot regulates root development in Arabidopsis thaliana. We do so using a combination of microscopy, gene expression, and mutant study approaches in a setup that allows root imaging without exposing the roots to light treatment. We show that low R:FR perception in the shoot decreases the lateral root (LR) density by inhibiting LR emergence. This decrease in LR emergence upon shoot FR enrichment is regulated by phytochrome-dependent accumulation of the transcription factor ELONGATED HYPOCOTYL 5 (HY5) in the LR primordia. HY5 regulates LR ...
Clinical features of outpatients with allergic rhinitis at E.N.T. department, Faculty of Medicine, Gadjah Mada University/Dr. Dardjito General Hospital Yogyakarta
To better understand links between the clock, environmental sensing pathways, and growth regulation, we are now collaborating with the Blackman Lab to study growth regulation in sunflower. Sunflower is well-known for diaheliotropism or solar tracking, with plants changing the angle of their leaves and stems over the day so that they remain perpendicular to the suns rays. This special type of rhythmic growth is found in many plants (including various crop and pasture species) and is associated with increased yield, likely due to increases in photosynthetic and water use efficiency [16, 17, 18]. The conspicuous movement of aerial organs from east to west during the day is likely mediated by activity of the phototropin blue light photoreceptors [19]. Much more mysterious is the reorientation that occurs during the night so that sunflower leaves and apices face east well before the sun rises (Figure 4) (see also Plants-In-Motion for a wonderful movie of a solar-tracking sunflower). Thus solar ...
When viewing electronic devices, myopically defocused blue light results in what is now termed digital eye strain. The Vision Council defines digital eye strain as "the physical eye discomfort felt by many individuals after two or more hours in front of a digital screen". In a 2014 survey conducted by VSP, eyecare providers reported a 50 percent increase in patient complaints of digital eye strain and effects of blue light exposure. Also stated was a 38 percent increase in these same complaints from children. Without intervention, reports containing statistics such as these will likely increase. The symptoms of digital eye strain can be broken down into three causes: proximity of the light source (digital device) to the eye, intensity of light from the source, and frequency and duration of exposure. In considering ways to alleviate symptoms, keeping these causes in mind can guide treatment recommendations.. Proximity. We tend to hold digital device screens closer to our eyes. This increases ...
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Transformants are often growing the wrong colour. LovTap controls the production of RFP in the cells. When LovTap is inactive (i.e. in the dark), the cells should be producing RFP and hence should be growing red. When LovTap is active (i.e. in white or blue light), the cells stop producing RFP and hence chould produce white colonies. At the moment some cells in the light are still growing red, although some are definitely growing white, and vice versa in the dark. One suggestion was that the plasmids are unstable and dividing randomly, altering the intensity of the colour in some cells. Attempts to stabilise the colours of the colonies are ongoing (see the video in the gallery which demonstrates one of the innovative methods of providing proper culture conditions).. ...
Transformants are often growing the wrong colour. LovTAP controls the production of RFP in the cells. When LovTAP is inactive (i.e. in the dark), the cells should be producing RFP and hence should be growing red. When LovTAP is active (i.e. in white or blue light), the cells stop producing RFP and hence should produce white colonies. At the moment some cells in the light are still growing red, although some are definitely growing white, and vice versa in the dark. One suggestion was that the plasmids are unstable and dividing randomly, altering the intensity of the colour in some cells. Attempts to stabilise the colours of the colonies are ongoing (see the video in the gallery which demonstrates one of the innovative methods of providing proper culture conditions). ...
Adam Gordon, O.D., discusses blue light, including the lack of clinical evidence in advertisements overstating dangers, as well as the effects of blue...
The blue light emitted by our technology affects us more than we realise! KIRSTY HUTTON shares why unnatural light exposure can be harmful and her top hacks to unplug.
As you probably already know, caffeine, especially when taken at the right time, boosts alertness and can improve your focus. New research suggests, however, that you could get even better brain benefits and more energy from being exposed to blue light.
Wanın Bahçesaray İlçesinde operasyona çıkan Türk ordusu ile HPGliler arasında yaşanan çatışmada 3 asker öldü. Wanda çatışma: 3 asker öldü Wanın Bahçesaray İlçesinde operasyona çıkan T
Oreksini ili hipokretini su pobuđivački neuropeptidni hormoni koje su simultano otkrile dve grupe istraživača u mozgu pacova.[1][2]. Dva srodana peptida (Oreksin-A i B, ili hipokretin-1 i -2), sa aproksimativno 50% identičnim sekvencama, nastaju presecanjem jednog prekurzornog proteina. Oreksin-A/hipokretin-1 ima 33 aminokiselina i dva intra-lančana disulfidna mosta, dok je oreksin-B/hipokretin-2 linearni peptid sa 28 aminokiselina. Studije su pokazale da oreksin A/hipokretin-1 možda ima veći biološki značaj od oreksina B/hipokretina-2. Mada se ovi peptidi proizvode u veoma maloj populaciji ćelija u lateralnom i posteriornom hipotalamusu, oni imaju uticaj na ceo mozak. Oreksin peptidi se vezuju za dva G-protein spregnuta oreksinska receptora, OX1 i OX2. Oreksin-A se vezuje za oba, OX1 i OX2, sa aproksimativno jednakim afinitetom, dok se oreksin-B vezuje uglavnom za OX2 i pet puta je manje potentan na OX1.[3]. ...
Ama : Sepsisten phe edilen hastalarda bakteriyeminin tan nmas sa kal m a s ndan olduk a nemlidir. Bakteriyemi varl n destekleyen veya d layan, etken patojen grubu hakk nda fikir verebilen, ucuz, h zl ve g venilir bir biyobelirte yararl olabilir. Bu al mada, yo un bak mda yatan, bakteriyemi saptanm sepsis hastalar nda prokalsitonin (PCT) d zeyinin etken olan patojen ile ili kisinin de erlendirilmesi ama lanm t r ...
Find patient medical information for Insulin NPH And Regular Human Subcutaneous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Autism Speaks is to autistic people as NAMI is to those with psych diagnoses. Both are harmful to our choice, voice, and ability to live life.
Higher plants have to cope with the environmental conditions at the place where they germinate and grow. Light is a key signal required for optimising their adaptation and survival. In the dark, a seedling undergoes skotomorphogenesis where it develops long hypocotyl, and apical hook and closed cotyledons. Under light, however, a seedling changes its developmental program to photomorphogenesis, resulting in a short hypocotyl, opened cotyledons, and the build-up of photosynthetic capacity. Plants have evolved multiple specialised photosensory systems to monitor changes in the surrounding light conditions. The photoreceptors Phytochromes regulate all aspects of photomorphogenic development of plants throughout their whole life-cycle including seed germination, seedling development, the shade avoidance response to detect and escape shading by photosynthetically active neighbors, entrainment of the circadian clock and the onset of flowering. Phytochromes have the capacity to steadily and rapidly ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
RH Plus is a new Japanese drama about 4 young vampires who live together as a family trying to live normal "human" lives but use their "gifts" to help solve crimes. Kiyoi, one of the 4 vampires, who actually looks about 21 years old, is actually over 100 years old. Makoto is the newest in the family. He was abandoned by his mother and most of the episodes revolve around the mystery of his life. Ageha is Makotos best friend and confident. Ageha is also not a vampire by "normal" means but is under a blood contract with Kiyoi, who saved him from the streets. Then we have Masakazu, the comedian primarily in the show. Always going on goukons (An organizer, either an individual or organization, invites several single men and women to get together in a social setting, such as a pub or restaurant. There they mingle. If two in the group happen to hit it off, they follow up with phone calls, dates - and perhaps eventually marriage.), he tries to compete with a fellow aged vampire for the most phone ...
Astrocytomas and oligodendrogliomas are subtypes of a brain cancer called glioma. These incurable brain tumors arise from glial cells, a type of support cell found in the central nervous system. "Low-grade gliomas", which grow comparatively slowly, spread in a diffuse manner across the brain and are very difficult to completely eliminate through surgery. In many cases, the effectiveness of treatments with chemotherapy and radiotherapy is very limited. Gliomas can develop into extremely aggressive glioblastomas. Low-grade gliomas have a particular feature in common: more than 70% of the cases exhibit the same gene mutation in tumor cells. An identical "typo" in the DNA causes the exchange of a single, specific protein building block (amino acid) in an enzyme called isocitrate dehydrogenase 1 (IDH1). As a result, most cancer cells do not follow the original building plan for the protein; at the 132nd position in the molecules sequence, they insert the amino acid histidine instead of ...
Every month, there seems to be more and more research that comes out about the effect of blue light on our health. A recent Harvard Health report states that artificial blue light and natural blue light from the sun are very different. Blue light from technology has four times the blue light that we get from the sun because blue light from the sun is balanced with red, green, infrared, and ultraviolet light.. Excess blue light creates Reactive Oxygen Species (ROS) and this creates inflammation, even during the day. It also diminishes the function of your mitochondria and then your body has less energy to do the things it needs to do on a daily basis. Many of us work in environments where there is artificial light all day, such as offices, hospitals, etc, and I know that we often cant get away from these environments, because its our job! But what you do have to try and do, is to get natural light into your eyes at any time of the day and on your days-off. This means getting outside into nature ...
World Class Research University which is innovative and excellent, serves to the interest of the nation and humanity, inspired by nations cultural values based on Pancasila, the state ideology
World Class Research University which is innovative and excellent, serves to the interest of the nation and humanity, inspired by nations cultural values based on Pancasila, the state ideology
According to the Centers for Disease Control and Prevention (CDC), all residents of areas where virus activity has been identified are at risk of getting West Nile encephalitis. Mosquitoes infected with the virus are being detected earlier than ever, according to the state Department of Environmental Protection. The first positive test occurred days earlier on…
Shop Amsterdam Expert Series Acrylics - Cobalt Blue Light (Ultramarine), 75 ml tube at Blick. Find everything you need for your next creative project online.
Chloroplasts change their position in a cell in response to environmental light conditions (Wada et al., 1993, 2003). Low-fluence rate light induces movement of chloroplasts toward the irradiated area, resulting in chloroplast accumulation at the front face of the cell (accumulation response). Conversely, under high-fluence rate light, chloroplasts move to the anticlinal wall of the cell to avoid photodamage (avoidance response; Kasahara et al., 2002). Chloroplast photorelocation movement is found in several photosynthetic plant species, including yellow and green algae, mosses, ferns, and flowering plants. In most plant species, chloroplast movement is induced by irradiation with blue light, although it is also induced by red light in some cryptogam plants (Wada et al., 1993, 2003). The flowering plant Arabidopsis (Arabidopsis thaliana) has two types of blue-light photoreceptor, cryptochromes (cry1 and cry2) and phototropins (phot1 and phot2). Cryptochrome is a flavoprotein similar to the ...
This experiment offers a simple, cheap and fun way to look at gravitropism over the course of a double lesson, using the strong gravitropic response of common dandelions.