Levels of inflammatory cytokines are raised in chronic obstructive pulmonary disease ( COPD). A diet rich in antioxidant vitamins may protect against the development of COPD. This study examined the effects of phenolic compounds and food sources on cytokine and antioxidant production by A549 cells. The effects of the following phenolic compounds on basal and interleukin ( IL)-1- stimulated release of IL-8, IL-6, and reduced glutathione (GSH) were examined: resveratrol; Bouvrage, a commercially available raspberry juice ( Ella Drinks Ltd., Alloa, Clacksmannanshire, UK); and quercetin 3 - sulfate. Purification of the raspberry juice by high- performance liquid chromatography gave three fractions: Fraction 1 contained phenolic acid and vitamin C, Fraction 2 contained flavonoids and ellagic acid, and Fraction 3 contained anthocyanins and ellagitannins. IL-8 production was increased in the presence of IL-1 ( 165 vs. 6,011 pg/mL, P ,.0001). None of the compounds tested had any significant effect on ...
Introduction: Octylphenol (OP) is a degradation product of alkylphenol ethoxylates that are widely used to in rubber, pesticides and paints. Bisphenol A (BPA) is an organic compound with two functional phenol groups and used to make polycarbonate plastic and epoxy resins, along with other applications. OP and BPA are known as endocrine disruptors that can induce inappropriate estrogenic action, and may disturb natural calcium metabolism. In the present study, the effects of OP and BPA on the calcium levels of serum and urine, and calcium transport genes were investigated in the duodenum, kidney and placenta of the pregnant mice.. Methods: From 6.5 to 16.5 days after post coitus (dpc), pregnant mice were orally given with ethylestradiol (EE, 0.2 mg/kg/day), OP (15, 45, or 135 mg/kg/day) or BPA (5 or 50 mg/kg/day) dissolved in corn oil. The duodenum, kidney, placenta, blood and urine were obtained from mice at day 18.5 of pregnancy.. Results: As a result, serum and urinary calcium levels were ...
Xenoestrogens such as alkylphenols and the structurally related plastic byproduct bisphenol A have recently been shown to act potently via nongenomic signaling pathways and the membrane version of estrogen receptor-α. Though the responses to these compounds are typically measured individually, they usually contaminate organisms that already have endogenous estrogens present. Therefore, we used quantitative medium-throughput screening assays to measure the effects of physiologic estrogens in combination with these xenoestrogens. We studied the effects of low concentrations of endogenous estrogens (estradiol, estriol, and estrone) at 10 pM (representing pre-development levels), and 1 nM (representing higher cycle-dependent and pregnancy levels) in combinations with the same levels of xenoestrogens in GH3/B6/F10 pituitary cells. These levels of xenoestrogens represent extremely low contamination levels. We monitored calcium entry into cells using Fura-2 fluorescence imaging of single cells. Prolactin
[103 Pages Report] Check for Discount on United States 2-Fluorophenol Market Report 2017 report by QYResearch Group. In this report, the United States 2-Fluorophenol market is...
Exposure to toxic industrial chemicals that have capacity to disrupt the endocrine system, also known as endocrine disrupting chemicals (EDCs), has been increasingly associated with reproductive problems in human population. Bisphenol A (BPA; 4,4-(propane-2,2-diyl)diphenol) and 4-tert-octylphenol (OP; 4-(1,1,3,3-tetramethylbutyl)phenol) are among the most common environmental contaminants possessing endocrine disruption properties and are present in plastics, epoxy resins, detergents and other commercial products of common personal and industrial use. A metabolite of BPA, 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP) is about 1000 times more biologically active compared to BPA. Epidemiological, clinical, and experimental studies have shown association of BPA and OP with adverse effects on male and female reproductive system in human and animals. The endocrine disruption activity can occur through multiple pathways including binding to steroid receptors. Androgen receptor (AR) and progesterone
Background & Objectives: Due to increase in  bacterial drug resistance, discovering new antibacterial compounds is really important. The objective of this study is to evaluate the phenol compounds effect on antibacterial activity of herbal extracts of Fasa-Fars province in vitro. Materials & Methods: The antibacterial activity of 26 plants was ...
Stagnant water bodies have generally received little attention regarding the presence of endocrine disruptive compounds, although they can integrate diverse pollutants from multiple different sources. Many compounds of anthropogenic as well as natural origin can contribute to the overall estrogenicity of surface waters and some of them can exhibit adverse effects on aquatic biota even in very low concentrations. This study focused on freshwater ponds and reservoirs affected by water blooms and determined the estrogenic activity of water by in vitro bioassay as well as concentrations of several important groups of estrogenic compounds (estrogenic hormones, alkylphenols, and phytoestrogens) by LC-MS/MS analyses. Estrogenic hormones were found at concentrations up to 7.1 ng.L-1, similarly to flavonoids, whose concentrations did not exceed 12.5 ng.L-1. Among alkylphenols, only bisphenol A and 4-tert-octylphenol were detected in levels reaching 100 ng.L-1 at maximum. Estrogenic activity of water ...
Is Bakuchiol a natural alternative to retinol? Ive put Boots Ingredients Bakuchiol Serum to the test to find out. Heres what happened...
This page contains information on the chemical 2,4-Dimethyl-3-(Chloromethyl)-6-Tert-Butylphenol including: 7 synonyms/identifiers.
Ahmed S, Atlas E. 2016. Bisphenol S- and bisphenol A-induced adipogenesis of murine preadipocytes occurs through direct peroxisome proliferator activated receptor gamma activation. Int J Obes Relat Metab Disord 40(10):1566-1573, PMID: 27273607, 10.1038/ijo.2016.95. Alonso-Magdalena P, Quesada I, Nadal Á. 2015. Prenatal exposure to BPA and offspring outcomes. Dose Response 13(2):1559325815590395, PMID: 26676280, 10.1177/1559325815590395. Alonso-Magdalena P, Vieira E, Soriano S, Menes L, Burks D, Quesada I, et al. 2010. Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring. Environ Health Perspect 118(9):1243-1250, PMID: 20488778, 10.1289/ehp.1001993. Anderson OS, Peterson KE, Sanchez BN, Zhang Z, Mancuso P, Dolinoy DC. 2013. Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course. FASEB J 27(4):1784-1792, PMID: 23345456, 10.1096/fj.12-223545. Angle BM, Do RP, Ponzi D, ...
Alkylphenols are widely used industrial chemicals that act as detergents or surfactants. They are added to cosmetics, paints, pesticides, detergents and cleaning products. As a group they are highly toxic to aquatic organisms. Dozens of recent studies have documented the in-vitro and in-vivo estrogenic activity of alkylphenols in human cell lines and animals (Bechi 2006). Alkylphenols have been detected recently in surface waters contaminated with urban runoff and in wastewater effluent (Espejo 2002; Oros 2003).. Alkylphenols have been measured in air samples. One study found that newer homes, especially those with PVC materials, have more alkylphenol residues than older houses or outdoor air (Saito 2004).. ...
Provided is a styrenated phenol compound represented by Formula 1 in which styrenated phenol and hydroxylamine bind to each other: In Formula 1, n is one of integers of 1 to 3, and R 1 and R 2 are each hydrogen or one of C1 to C4 alkyl groups. The styrenated phenol compound may maintain curing stimulation property and plasticity, and prevent discoloration when being mixed with a curing agent ...
Among the commonly reported tapentadol ER side effects are headaches, nausea, and constipation. This eMedTV page offers an overview of other possible reactions, listing common ones as well potentially serious problems that require medical treatment.
Anti-agers may have a new play in the wrinkle-reduction game. Bakuchiol was shown in a recent study to match the established benefits of retinol.
Available in: Hardcover. A collection of current knowledge of phytochemicals and health Interest in phenolic phytochemicals has increased as
A HPLC method for simultaneous determination of 25 phenolic compounds in grape juice was optimized, validated and applied in the characterization of juices produced in São Francisco Valley (SFV), Brazil. The performance char- acteristics of the method were established by assays with standard solutions of phenolic compounds, spiked and unspiked samples. Linearity, matrix effects, trueness, precision, detection and quantification limits were evaluated. Linearity was demonstrated in the concentration ranges tested for all phenolic compounds. Significant matrix ef- fects were not identified for the studied compounds. Mean recoveries ranged from 86.18 to 106.50%, demonstrat- ing no lack of trueness. Precision of the method was confirmed for the 25 phenolic compounds, with acceptable repeatability relative standard deviations (from 0.71 to 9.24%) and within-reproducibility relative standard devia- tions (from 1.34 to 9.26%) for unspiked and spiked samples. The theoretical limits of detection and ...
Phenolic compounds are important components of grapes and wines. They have been found to have important roles in grape and wine systems and properties that are beneficial for human health. Vanillin (3-methoxy-4-hydroxy ...
Bisphenol A BPA Definition - Bisphenol A (BPA), is a chemical found in clear plastics. Medical research has determined that exposure to BPA has a direct...
This topic contains 40 study abstracts on Bisphenol A indicating it may contribute to Prenatal Chemical Exposures, Bisphenol-A Toxicity, and Obesity
This topic contains 40 study abstracts on Bisphenol A indicating it may contribute to Prenatal Chemical Exposures, Bisphenol-A Toxicity, and Obesity
New research presents another cause for concern in regard to the chemical bisphenol A (BPA). The study is the first to examine what impact BPA has on the DNA of mammary glands as they age.
Bisphenol A is an endocrine disrupting chemicals that can give someone with mild PMS a really bad case of PMS. When toxicity of Bisphenol A builds in the body, hormones throughout the body are effected.
The ACQUITY UPLC Bisphenol A Method Kit is fully compliant with ASTM Method D7574-09. As described in this method, the ACQUITY solution provides optimum resolution and sensitivity for the analysis of Bisphenol A in water.
86 per cent of teenagers have traces of Bisphenol A (BPA), a chemical compound used to make plastics, in their body, an Engaged Research public engagement project in collaboration with the University of Exeter has found.
Get Bisphenol A type Compounds at Spectrum Chemical. SpectrumChemical.com carries a full line of fine chemicals, lab appliances and lab supplies. Spectrum Chemical offers fine chemicals in lab and production sizes.
The TriRNA Pure Kit is a spin column system for purification of high-quality total RNA from a variety of samples. Initially, samples are homogenized in TRIzol® Reagent, GENEzol™ Reagent or other phenol, guanidine isothiocyanate reagents. Chloroform phase separation or isopropanol RNA precipitation is not required.
The TriRNA Pure Kit is a spin column system for purification of high-quality total RNA from a variety of samples. Initially, samples are homogenized in TRIzol® Reagent, GENEzol™ Reagent or other phenol, guanidine isothiocyanate reagents. Chloroform phase separation or isopropanol RNA precipitation is not required.
Exposure to bisphenol A may reduce the effectiveness of chemotherapy treatments by inducing a group of proteins that protect cancer cells from the toxic effects of chemotherapy.
You are viewing an interactive 3D depiction of the molecule 4,4-(2,3-diisocyano-1,3-butadiene-1,4-diyl)bisphenol (C18H14N2O2) from the PQR.
[169 Pages Report] Check for Discount on 2017-2022 Global Top Countries Hydrogenated Bisphenol A Market Report report by LP Information INC. ...
Dietary phenolic compound with the presence of C2=C3 double bond take the pre-emptive opportunities to enhance its biological effects., Lei Chen
Mounting evidence against a chemical we are exposed to daily is being ignored. What more do regulators need, ask David Melzer and Tamara Galloway
phenomenon can be attributed to several factors: First, due to the changes in the content of various phenolic compounds and second, to an increase in cell sap pH level. Sood and Nagar (2003) and Sood et al. (2006) investigated the levels of acidic and. ...
In the current study, all infants had detectable urinary concentrations of total BPA, ranging from 2.0 to 196 µg/L. The median urinary BPA concentration in this group of premature infants was considerably higher (17.2 μg/L) than in healthy term infants aged 1 to 5 months (,0.45 μg/L) without known BPA exposure.21 Although immaturity of phase II metabolism may account for some of the association of urinary BPA concentrations with prematurity, premature infants have the ability to conjugate BPA.16 Interestingly, medical devices, but not nutritional intake, were positively associated with urinary BPA concentrations. On average, premature infants requiring ≥4 medical devices had urinary total BPA concentrations 1.6 times higher than those requiring fewer devices independent of their gestational age, gender, or nutritional intake. Respiratory devices were associated with higher urinary BPA concentrations than other devices. These findings suggest that medical devices were an important source of ...
Gestational urinary BPA concentrations were associated with some neurobehavioral measures at 3 years of age in this cohort. In particular, gestational BPA exposure was associated with higher scores for measures of anxiety, hyperactivity, emotional control, and behavioral inhibition. Similar to our previous findings, the effects of gestational BPA exposure on these behavioral domains were larger among girls than boys.2 The different responses to gestational BPA exposure were especially pronounced for hyperactivity; girls exhibited increases in hyperactivity, and boys exhibited decreases in hyperactivity. In contrast, childhood urinary BPA concentrations were less important predictors of behavior or executive functions in this study.. The findings presented are consistent with numerous studies demonstrating altered neurobehavior among BPA-exposed animals.14,38 Gestational BPA exposures might affect endocrine or other neurotransmitter pathways and disrupt sexual differentiation of the brain, to ...
NIEHS Grant P30ES000002. A study, supported in part by the NIEHS, identified medical devices as a potential source of exposure to bisphenol A (BPA) among premature infants in neonatal intensive care units. BPA is used to manufacture polycarbonate plastics, which are used in medical devices such as intravenous administration sets, syringes, and catheters. The researchers looked at the urinary BPA concentration for 55 infants and categorized each infants medical device use as low or high based on the number and invasiveness of devices. They found that the median urinary total BPA concentration of infants who had required four or more medical devices for three previous days was significantly higher, 36.6 micrograms per liter (µg/l), than for the infants requiring three or less devices, who had a BPA concentration of 13.9 µg/l. The researchers also collected and analyzed breast milk or formula samples, and found that the increased BPA concentration was not associated with the infants nutritional ...
ALBERTO, María R.; MANCA DE NADRA, María C. and ARENA, Mario E.. Influence of phenolic compounds on the growth and arginine deiminase system in a wine lactic acid bacterium. Braz. J. Microbiol. [online]. 2012, vol.43, n.1, pp.167-176. ISSN 1517-8382. http://dx.doi.org/10.1590/S1517-83822012000100018.. The influence of seven phenolic compounds, normally present in wine, on the growth and arginine deiminase system (ADI) of Lactobacillus hilgardii X1B, a wine lactic acid bacterium, was established. This system provides energy for bacterial growth and produces citrulline that reacts with ethanol forming the carcinogen ethyl carbamate (EC), found in some wines. The influence of phenolic compounds on bacterial growth was compound dependent. Growth and final pH values increased in presence of arginine. Arginine consumption decreased in presence of protocatechuic and gallic acids (31 and 17%, respectively) and increased in presence of quercetin, rutin, catechin and the caffeic and vanillic phenolic ...
It is in your food containers, water bottles, and 90 percent of us have it in our bloodstream. It may also be a prime candidate for causing wheezing in children if pregnant mothers come into contact with it. Experimental research in bisphenol A, (BPA) suggests that prenatal BPA exposure causes asthma in mice. No firm data yet exists for humans but results are not looking good.. Adam Spanier, M.D., Ph.D., assistant professor of pediatrics at Penn State College of Medicine, studied 367 children, 99 percent of whom were born to mothers who had detectable BPA levels during pregnancy. Twice a year for three years, the parents reported back with any signs of wheezing in the children. At six months of age, twice as many children were reported with wheezing from mothers who had higher BPA than those who had mothers with lower BPA levels. These effects may have diminished as the children aged however.. Researchers then looked at the levels of BPA in the women during certain times of their pregnancies and ...
Early buyers will receive 10% customization on reports.. This growth is driven by rising demand from Asia-Pacific region due to highly industrialized countries, such as China. Phenol derivatives are preferred for the production of polycarbonates, epoxy resins, bakelite, and nylon.. Bisphenol -A: The most-widely used derivative of phenol derivatives. Bisphenol-A is a phenol derivative commonly used for producing polycarbonates and epoxy resins. The bisphenol-A is the most-widely used derivative of phenol. Polycarbonate finds application in food and drink packaging such as water & baby bottles, compact discs, impact-resistant safety equipment, and medical devices. Further, epoxy resins used to coat metal products such as food cans, bottle tops, and water supply pipes. BPA is also be found in certain thermal paper products, including cash register and ATM receipts.. Asia-Pacific: The largest market for phenol derivatives. The Asia-Pacific region is the largest market in the global phenol ...
TY - JOUR. T1 - Oxygen radical absorbance capacity (ORAC) of cyclodextrin-solubilized flavonoids, resveratrol and astaxanthin as measured with the ORAC-EPR method. AU - Sueishi, Yoshimi. AU - Ishikawa, Misa. AU - Yoshioka, Daisuke. AU - Endoh, Nobuyuki. AU - Oowada, Shigeru. AU - Shimmei, Masashi. AU - Fujii, Hirotada. AU - Kotake, Yashige. PY - 2012/3. Y1 - 2012/3. N2 - Recently, we proposed an oxygen radical absorbance capacity method that directly quantifies the antioxidants scavenging capacity against free radicals and evaluated the radical scavenging abilities for water soluble antioxidant compounds. In this study, we determined the radical scavenging abilities of lipophilic antioxidants which were solubilized by cyclodextrin in water. Commonly employed fluorescence-based method measures the antioxidants protection capability for the fluorescent probe, while we directly quantify free-radical level using electron para- magnetic resonance spin trapping technique. In addition, the spin ...
NIEHS Grants: R01ES016541, P01ES022844, P30ES017885, R01ES017005, R01ES017005, R01ES016001, R01ES017524. NIEHS grantees report that exposure to the endocrine-disrupting chemical bisphenol A (BPA) during pregnancy can cause oxidative damage that may increase a childs risk of developing diabetes or heart disease later in life. The researchers tested multiple species of animals to replicate and strengthen human studies that showed BPA exposure during pregnancy can bring about a specific type of oxidative stress.. Oxidative stress is associated with insulin resistance and inflammation, which are risk factors for diabetes and other metabolic disorders as well as cardiovascular disease. For the human study, the researchers analyzed blood samples from 24 mother and infant pairs. The women were divided into two groups based on their levels of BPA determined from blood draws taken during their first trimester of pregnancy. Mothers and their infants with higher levels of BPA showed increased levels of ...
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Possible link between high prenatal BPA levels and neonatal neurobehavioral abnormalities; study advises pregnant women to reduce exposure levels. A new case study examining an infants neurobehavioral abnormalities and extremely high bisphenol A (BPA) concentration of the babys mother suggests a link between the two. The study, Environmental Health Perspectives: A Case Study of High Prenatal Bisphenol A Exposure and Infant Neonatal Neurobehavior, was led by researcher Sheela Sathyanarayana, MD of Seattle Childrens Research Institute, and recently published online in Environmental Health Perspectives.. BPA, a synthetic, man-made chemical, is used in a wide variety of products including: can linings; hard polycarbonate plastics such as baby bottles and reusable cups; and dental sealants. Food may be the single largest source of BPA exposure due to contamination of foods during preparation and processing. BPA has estrogenic (hormone-like) properties. In animal studies, exposure to BPA early in ...
Arnold J. Schecter and colleagues note that BPA is used in lining metal cans and in polycarbonate plastics such as baby bottles, although some manufacturers are switching to BPA-free products. "In humans, BPA is associated with cardiovascular disease, diabetes, and male sexual dysfunction in exposed workers," they state. "Food is a major exposure source. We know of no studies reporting BPA in U.S. fresh food, canned food, and food in plastic packaging in peer reviewed journals." To fill that gap in scientific knowledge, the scientists measured BPA levels in 105 human, cat, and dog foods. They detected BPA in 63 of 105 human food samples from grocery stores in Dallas, and present a detailed list of foods, brands, and BPA levels in the text of the study. The levels were lower than the 50 micrograms per kilogram of body weight standard used by EPA and EFSA and comparable to levels detected in the past. Schecter noted that some studies have shown adverse effects associated with exposure to BPA at ...
If youre going through fertility treatments you may want to limit your BPA exposure. A Harvard study links BPA exposure to lower IVF success rates.
The amounts of total polyphenol and flavonoids in the Korean EEP samples ranged from 49 to 239 mg gallic acid equivalent (GAE)/g EEP (Brazilian, Chinese, and Australian samples, 127-142 mg GAE/g EEP) and from 21 to 50 mg quercetin equivalent (QE)/g EEP (Brazilian, Chinese, and Australian samples, 33-53 mg QE/g EEP), respectively. Correlation coefficient analysis showed that total polyphenol contents may be negatively correlated with 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity (r = -0.872) and total flavonoid content has no correlation with the activity (r = 0.071). No direct correlation between BACE-1 inhibition, AChE inhibition, or antiproliferative activity and total polyphenol or total flavonoid content in Korean EEP samples was found. Gram-positive and Gram-negative bacteria were observed to have different degrees of antimicrobial susceptibility to the EEP samples examined, although ciprofloxacin susceptibility among the bacterial groups did not differ greatly ...
MSNBC is reporting on a new study that found eating canned food every day may raise the levels of the compound bisphenol A (BPA) in a persons urine more than previously suspected, a new study suggests.. The study found people who ate a serving of canned soup every day for five days showed higher levels of BPA in their systems than those who ate no soup. The participants who ate soup during the five day test had BPA levels of 20.8 micrograms per liter of urine, whereas people who instead ate fresh soup had levels of 1.1 micrograms per liter, according to the study.. Food Court previously reported on BPA findings in popular childrens soups. In that case, and here, BPA is found in many canned foods - it is a byproduct of the chemicals used to prevent corrosion.. When the researchers looked at the rise in BPA levels seen in the average participant who ate canned soup compared with those who ate fresh soup, they found a 1,221 percent jump.. The FDA does not currently regulate BPA levels and is ...
An ongoing debate about the health impacts of bisphenol A (BPA), the ubiquitous chemical used in production of polycarbonate - that hard clear plastic we use for eating, drinking, and storing food - continues, according to a recent article by Janet Raloff published in the September 29 issue of Science News. Her analysis provides good insight into why we often hear conflicting reports when it comes to environmental and health impacts of chemicals.. Raloff reports on the conflicting results of two different panels recruited by the National Toxicology Program (NTP) and charged with reviewing and evaluating the potential developmental and reproductive impacts of BPA. While one panel "labeled as confident its assessment that BPA at low doses has had negative effects on experimental animals," and that such findings were suggestive of impacts in humans, the other panel "concluded that current BPA exposures appear to pose little risk to humans.". According to Raloff, one of the differences cited in ...
Several activated carbons (ACs) were used as metal-free catalysts for degradation of a toxic organiccompound, phenol, in the presence of different oxidants, H2O2, peroxydisulfate (PS) and peroxymonosulfate (PMS). It was found that ACs were effective in heterogeneous activation of PMS toproduce sulfate radicals for degradation of phenol, much better than H2O2 and PS. Particle size of AC significantly influenced AC activity, and powder AC was much more effective than granular AC. The complete phenol removal could be achieved in 15 min on powder activated carbon (PAC) under the conditions of [phenol] = 25 mg L-1, [PAC] = 0.2 g L-1, [PMS] = 6.5 mmol L-1, and T = 25 degrees Celcius. It was also found that phenol degradation was significantly influenced by PMS loading, catalyst loading, phenol concentration and temperature. Surface activation of PMS and phenol adsorption played important roles in phenol degradation. Surface coverage by intermediate adsorption and structural change induced deactivation ...
Stearyl .beta.-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate Stearyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate Stearyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate Sumilizer BP 76 THANOX 1076 U 276 Total tonnage band Total range: 10 000+ tonnes per annum REACH Registered as: FULL Submitted: Joint Submission Publication dates First published ...
Introduction. 1. Give an account of the properties and uses of phenol. (1) Phenol is acidic and its conjugate base, phenoxide ion is stabilized by resonance. However, phenol is not acidic enough to liberate CO2 from phenol because an aqueous solution of carbon dioxide is a stronger acid than phenol. An aqueous solution of phenol has a pH value of 9. This means phenol reacts with NaOH but not NaHCO3. Phenol dissolves in NaOH(aq) to form sodium phenoxide, an ionic salt. (2) Phenol is corrosive and is a useful antiseptic. (3) Phenol is a colorless solid of low melting point. Its pink appearance is due to the presence of impurities. (4) When attached to a benzene ring, a hydroxyl group does not show the properties of an alcohol. The delocalization of electrons into the ring makes the -OH group inert towards replacement. On the other hand, the -OH group activates the ring toward electrophilic substitution at the ortho- and para-positions. Therefore, phenol reacts with (a) NO2+, (b) CH3+, (c) CH3CO+, ...
Unscramble phenols, Unscramble letters phenols, Point value for phenols, Word Decoder for phenols, Word generator using the letters phenols, Word Solver phenols, Possible Scrabble words with phenols, Anagram of phenols
The study conducted by researchers at the Harvard School of Public Health (HSPH) found that a group of volunteers who consumed a serving of canned soup each day for five days had a more than 1,000 percent increase in urinary bisphenol A (BPA) concentrations compared with when the same individuals consumed fresh soup daily for five days ...
The list of adverse health effects from BPA exposure continues to grow. Bisphenol A, or BPA, is commonly used to line food and beverage cans, and helps to keep plastics flexible, but studies suggest the compound can leach into the foods we eat.
The list of adverse health effects from BPA exposure continues to grow. Bisphenol A, or BPA, is commonly used to line food and beverage cans, and helps to keep plastics flexible, but studies suggest the compound can leach into the foods we eat.
Figure 6: Antioxidant, Cytotoxic, and Antiproliferative Activities and Total Polyphenol Contents of the Extracts of |i|Geissospermum reticulatum|/i| Bark
Phenol is one of toxic pollutants in many kinds of hypersaline industrial effluents which should be treated properly before discharged into water bodies. In this work, a halophilic strain which could utilize phenol as the sole source of carbon and energy was isolated. Based on 16S rRNA results, it was identified as a member of Citrobacter. The phenol biodegradation ability and cell growth of the strain was evaluated with the variation of initial phenol concentration and salinity. The effect of temperature and pH on phenol removal was also investigated. The results showed that the strain was capable of withstanding high phenol (up to 1,100 mg L−1) environment with varying salinity conditions (0-10% of NaCl). The optimal initial phenol concentration was 400 mg L−1, with which the average removal rates of phenol peaked at 10.8 mg L−1 h−1. The higher initial concentration of phenol could inhibit the microbial metabolism. The optimal temperature, pH and salinity were 35 °C, 6.0, and 0%, ...
Current human exposure to bisphenol A (BPA), a chemical used in many polycarbonate plastics and epoxy resins, is of some concern for effects on development of the prostate gland and brain and for behavioral effects in fetuses, infants and children, according to a final report released today by the National Toxicology Program (NTP).
Data & statistics on Bisphenol India: Dilution table for bisphenol A and bisphenol F., Properties of two types of polycarbonates, that is, Bisphenol A polycarbonate (BPAPC) and Poly(diethylene glycol di(allyl carbonate)) (PDEGDAC) [2]., Gharravi AM, et al: Altered pituitary hormone in male rats exposed to Bisphenol A...
New research led by researchers at North Carolina State University shows that exposure to the chemical bisphenol A (BPA) early in life results in high levels of anxiety by causing significant gene expression changes in a specific region of the brain called the amygdala. The researchers also found that a soy-rich diet can mitigate these effects.. "We knew that BPA could cause anxiety in a variety of species, and wanted to begin to understand why and how that happens," says Dr. Heather Patisaul, an associate professor of biology at NC State and lead author of a paper describing the work. BPA is a chemical used in a wide variety of polycarbonate plastics and epoxy resins, and is used in consumer products such as some food containers.. In the study, rats were exposed to low doses of BPA during gestation, lactation (nursing) and through puberty. One group of animals was fed only soy; one group was fed a soy-free diet; one group was fed only soy and exposed to BPA; and one group was fed no soy and ...
Silica-gel column chromatography (clean-up). The chromatographic column (20 cm × 8 mm I.D.) was packed with 5.0 g of activated silica gel, which was made into a slurry with 1.5% (v/m) petroleum ether and then stirred well before use. About 1 mℓ of anhydrous sodium sulphate was placed at the top of the column to absorb any water in the sample or the solvent. The column was pre-eluted with 15 mℓ of petroleum ether and before exposure to sodium sulphate. The reduced 5 mℓ extract resulting from the extraction processes was placed in the column and allowed to sink below the sodium sulphate layer. APEs extracts were eluted with 2 × 10 mℓ portions of the extracting solvents. The eluant was collected, bubbled with nitrogen gas to dryness and reconstituted with 2 mℓ of extracting solvent. Then 1.0 µℓ was injected into the GC.. Sampling protocol. Description of the study area. The study area for this research work was the Jukskei River catchment area, which is located in the Gauteng and ...
Research has called into question the role of plant polyphenols in cardiovascular health, by finding that their supposed anti-platelet activities are only relevant at high, and physiologically unattainable, concentrations.
Exposure to the endocrine-disrupting chemical bisphenol A during pregnancy can cause oxidative damage that may put the baby at risk of developing diabetes or heart disease later in life, according to a new study published in the Endocrine Societys journal Endocrinology.
The aim of the study was to determine total phenolics, flavonoid contents and antioxidant activity in some Eulophia species (Orchidaceae). Rhizomes of Eulophia species viz. E. nuda, E. ochreata, E. herbacea, E. ramentacea, E. andamanensis and E. epidendrea were extracted with petroleum ether, methanol, acetone and Distilled water.
... are a diverse group of phytonutrients that determine colours of the fruits and vegetables, and protect the plants from diseases and invasion of external microorganisms. In fact, polyphenols are a part of defense mechanisms of the plants.. Polyphenols are classified into two major groups, flavonoids and phenolic compounds. A subtype of phenolic compounds is lignans, which are one of the major subclasses of phytoestrogens as well.. See "Flavonoids" and "Phenolic Compounds".. ...
You are looking for 2,6-di-tert-butyl-4-(4,6-bis(octylthio)-1,3,5-triazin-2-ylamino)phenol from Kuo Ching Chemical Co., LTD ? ...
2,4-Di-tert-butyl-6-(tert-butylamino)phenol | C18H31NO | CID 534770 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
The objective of the present study was to examine the effects of neonatal exposure to either agonists or antagonists of androgen and estrogen receptors on the expression of growth and differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) and their cognate receptors (TGFBR1, BMPR1B, and BMPR2) in ovarian follicles of adult pigs. Piglets were injected subcutaneously with testosterone propionate (TP, an androgen, at 20 mg/kg bw), flutamide (FLU, an antiandrogen, at 50 mg/kg bw), 4-tert-octylphenol (OP, an estrogenic compound, 100 mg/kg bw), ICI 182,780 (ICI, an antiestrogen, 400 μg/kg bw), or corn oil (control) between postnatal Days 1 and 10 (n = 5/group). Ovarian follicles were excised from adult pigs on Days 8-11 of the estrous cycle. The expression of GDF9, BMP15, TGFBR1, BMPR1B and BMPR2 were examined in the population of preantral and small antral ovarian follicles using real-time PCR, Western blot and immunohistochemistry. In preantral follicles, the upregulation of GDF9 mRNA
Cardiovascular and anti-inflammatory health benefits of extra virgin olive oil are well-known facts. However, the balanced fatty acid composition and the unique polyphenol content of olive oil have other less discussed effects for human health. According to Wikipedia, olive oil is a source of at least 30 phenolic compounds, which possess powerful antioxidant and anti-inflammatory… Read More ...
gave the highest values of flavonoid (741.36mg/NGN/g DW and 220.53mg/NGN/g DW), phenolic acid (42.71mg/GAE/g DW and 22.03mg/GAE/g DW) and polyphenols (39.38mg/GAE/g DW and 38.01mg/GAE/g DW) respectively. Significant and positive linear correlations were found between Total antioxidant capacity and Phenolic compounds (R = 0.65 - 0.96 ...
Most of us are aware that there are lots of dangerous materials like additives, dyes, pesticides and carcinogens in our foods. What many of us are not aware of is that in the containers that our foods come in, especially take out, there are chemicals in the materials that may be even more harmful than the additives, dyes and pesticides.. By now you have probably heard of the dangers of the toxic chemical Bisphenol A (BPA). This chemical can be found in polycarbonate plastic food containers, bottles and takeout food containers. Numerous articles have been written on breast cancer and prostate cancer that result from exposure to the BPA contained in packaging and containers that carry food stuffs.. Recent, important environmental health study findings were published in March in the online journal Environmental Health Perspectives. A study was conducted by two organizations concerned with the environmental causes of breast cancer, the Breast Cancer Fund and Silent Spring Institute. The study was on ...
Phenols are among the highest-volume chemicals in production [ 3]. International organizations such as Agency for Toxic Substances and Disease Registry (ATSDR) [ 1] have documented phenol toxicity and recommend the monitoring of phenol exposure for groups at risk. The toxicity includes CNS depression and other symptoms such as skin burns, nausea, profuse sweating [ 1]. In exposure- and risk- evaluation, the monitoring of phenol by peripheral biomarker has several advantages over technical assessment of exposure. The urine methyl hippuric level is an acceptable peripheral biomarker for phenol exposure [ 1]. It was concluded that the phenol can be used for crude phenol exposure categorizations. Phenol is an important contamination in traffic fume [ 3]. High phenol exposure among the population living in the urban area of big city can be expected. Here, the author studied the urine phenol level among healthy subjects in urban area in Bangkok. We recommend that annual check up and monitoring for ...
* found in: Phenol:Chloroform(pH6.7/8.0), Phenol:Chloroform 5:1 (pH4.5), Phenol S/P Buffer-Saturtd, Phenol:Chloroform Low pH, Phenol, Crystalline, Phenol..
Canadian Health Minister Tony Clement (pictured left) announced yesterday that Bisphenol A would be listed as a toxic substance and banned the use of polycarbonate plastic baby bottles. His Ministry will also tell baby food manufacturers to get it out of
Article Removal of phenol from saline water by polyamine chelating resin. Removal of phenol from saline water was carried out with chelating resin. A polyamine chelating resin, Diaion CR-20, removed phenol compounds selectively from industrial wastew...
ARLINGTON, Va., Jan. 15 /PRNewswire-USNewswire/ -- American Chemistry Council Reacts to Statement from HHS and FDA on Bisphenol A.
Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate transcriptional activator senses the inducing chemical. Creation of bacterial biosensors is currently restricted by limited knowledge of the genetic systems of bacteria that catabolize xenobiotics. By using mutagenic PCR to change the chemical specificity of the Pseudomonas species CF600 DmpR protein, the potential for engineering novel biosensors for detection of phenols has been demonstrated. DmpR, a well-characterized transcriptional activator of the P. CF600s dmp operon mediates growth on simple phenols. Transcription from Po, the promoter heading the dmp operon, is activated when the sensor domain of DmpR interacts with phenol and mono-substituted phenols. By altering the sensor domain of the DmpR, a group of DmpR derivatives that activate transcription of a Po-lacZ fusion in response to eight of the EPAs
  Various aromatic rice varieties such as Kalizira, Begun Bichi, BRRI dhan-34, BRRI dhan-37, BRRI dhan-50, Philipine Katari were analyzed for physiochemical, total phenol, flavonoid contents and functional properties. All aromatic rice varieties had moisture contents (11.25 to 15.13%), protein (3.23 to 6.21%), fat (0.68 to 1.45%) and ash (0.88 to 1.46%). The maximum amount of amylose and starch content were obtained in BRRIdhan-37 and BRRI dhan-50 (23.01 and 72.606%, respectively). Total phenolic content was higher in BRRI-37 (474 mg/100 g); whereas, lower value was observed in BRRIdhan-34 (268.67 mg/100 g) variety. Both Philipine Katari and kalizira variety possessed highest level of flavonoid content among all rice varieties. Highest water absorption index value was found in BRRI dhan-37 and lowest in Begun Bichi variety. On the other hand, water soluble index value was varied by 1.32 to 2.12% in all aromatic rice varieties.Therefore, the
To account for the observed anticancer properties of plant polyphenols, we have earlier proposed a mechanism which involves the mobilization of endogenous copper ions by polyphenols leading to the gen
Octylphenol (OP) and nonylphenol (NP) are known to be endocrine disrupting agents and found as degradation products of industrial detergents, OP- and NP-polyethoxylates, in the natural environment. Previously, a bacterium (YTT) able to degrade OP and NP was isolated from a river sediment sample and identified as a novel species, Sphingobium amiense, in the class Alphaproteobacteria. In this study, we analyzed the whole genome sequence of strain YTT to characterize the OP degradation gene. Genomic DNA of the strain YTT sequenced by the whole-genome sequencing method with MiSeq and annotated using the BLASTP program. The total assembled genome was 4,565 kbp, for which 4,445 coding sequences were predicted. Prior to the genomic study, the mass spectrometry analysis revealed that octylhydroquinone and hydroquinone (HQ) were the intermediates of 4-tert-OP degradation by strain YTT . From the genomic analysis, the strain was found to possess the gene encoding octylphenol 4-monooxygenase, catalyzing ...
Coating the mouth with BPA-containing food, like soup, does not lead to higher than expected levels of BPA in blood, a new study in Toxicology and Applied Pharmacology shows. The study authors conclude that oral exposure does not create a risk for high exposures of BPA, also known as bisphenol A.
Phenol is moderately soluble in water - about 8 g of phenol will dissolve in 100 g of water. If you try to dissolve more than this, you get two layers of liquid. The top layer is a solution of phenol in water, and the bottom one a solution of water in phenol. Phenol is somewhat soluble in water because of its ability to form hydrogen bonds with the water.. ...
If youve been paying any attention to the headlines lately, then youve probably heard the uproar about bisphenal A (BPA). If youre worried about BPA showing up in in unlikely places, like your canned chicken noodle soup, for instance, then youre not the only one.. When I first heard about the dangers of BPA it seemed as if it was limited to baby bottles and water bottles, Nalgene bottles in particular. So I ditched my Nalgene and went with a stainless steel bottle. I thought that was the end of the story.. But, BPA is in a lot of the things we use everyday. And, thats disturbing to me. So, Im putting on my Sherlock hat and going investigating.. What Is BPA?. Bisphenal A is a chemical compound that was originally discovered in 1891. It was shelved in favor of other chemicals at the time, but revived many years later when a polymer chemist discovered it could be used to form polycarbonate plastic.. The bad news is that the ester bonds that link the BPA monomers together are not very stable. ...
Increased intakes of polyphenols may reduce the risk of cardiovascular disease by an impressive 46%, according to the results of the international PREDIMED (Prevencion con Dieta Mediterranea) study.
Last year, FDA disappointed us by insisting that there was no cause for concern about the presence of the chemical bisphenol A in food and beverage containers. An expert panel charged with evaluating the FDAs draft assessment strongly criticized the agency for its severely limited exposure assessment and the criteria it used to assess BPA studies. Then, Suzanne Rust and Meg Kissinger of the Milwaukee Journal Sentinel (whove won multiple awards for their coverage of BPA and other chemicals) reported that FDAs report "was written largely by the plastics industry and others with a financial stake in the controversial chemical.". Yesterday, the agency finally announced that its reviewing new studies about BPA and will let us know by the end of November whether its safe to use the chemical in food and beverage containers. Meg Kissinger has the story, and you can check out the Journal Sentinels "Chemical Fallout" series for more background.. ...
Children and adolescents with higher concentrations of urinary bisphenol A (BPA), a manufactured chemical found in consumer products, had significantly increased odds of being obese, a study has found. Leonardo Trasande, M.D., M.P.P., of the NYU
A. Culețu, D. E. Duță, G. Mohan, E. Iorga, 3rd IMEKOFOODS, Metrology Promoting Harmonization & Standardization in Food & Nutrition, Book of Proceedings - 4 Book of Posters, 2017, 337-340
Emerging research reveals that the ubiquitous polycarbonate plastics chemical, bisphenol A (BPA), has adverse effects in expectant mothers.. According to the new UC Berkeley study, BPA appears to change thyroid hormones, which are critical to healthy growth, said SFGate. The change was evident in both pregnant women and newborn baby boys, said the researchers.. As weve long explained, BPAs links to reproductive system diseases are staggering and span to fetal development, likely due to its hormone-mimicking and -blocking properties. Issues include effects on uterine health and mammalian reproduction; a deadly uterine infection; premature puberty; Polycystic Ovarian Syndrome (PCOS) and other female fertility and endocrine issues; and erectile dysfunction and male sexual problems. Significantly, BPAs effects have been found to be immediate, long lasting, and trans-generational, meaning effects could carry years into the future. Despite all this, the FDA said the information on BPA does not ...
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. Intense Research has been recently published a fresh research report- Global 2-Methoxy-5-nitro Phenol (CAS 636-93-1) Market - By - Manufacturers, States, Type and Application, Forecast to 2021 - By - Manufacturers, States, Type and Application, Forecast to 2021. This added to the companys collection of research reports. This report offers a deep examination of the 2-Methoxy-5-nitro Phenol (CAS 636-93-1) market for the period 2013-2023. As per the report, the 2-Methoxy-5-nitro Phenol (CAS 636-93-1) market is estimated to grow at elevated CAGR recorded in 2017. The towering competitive 2-Methoxy-5-nitro Phenol (CAS 636-93-1) market has been observing huge and whooping investments in development and research from government as well as private firms.. This report divides the market on the basis of regions, manufacturers, application, and type. It also showcases the growing factors, reasons for decline in the market, ...
Latest Amino Phenol Exports data, Exporters list and shipment data of indian customs, Amino Phenol Exporters in India, Amino Phenol Exports Value with HSN CODE & Ports wise
... are highly corrosive and poisonous crystals. The lethal dose for a human is about 15 g but as small quantity as 1 g has caused deaths. Phenol is used in the production of colourants, explosives and detergents.. ...
This research paper studies the development of a sustainable process for the extraction of antioxidants from oat. Experimentation covered two factorials to evaluate significance among temperature, time, particle size and solvent. Total polyphenolic content (TPC) and oxygen radical absorbance capacity (ORAC) were the response variables. ANOVA was applied to find significance among variables and predict optimum conditions though a regression model. Extractions at different solid/solvent ratios were developed to study solvents solubility. Process simulation in Aspen Process Developer was carried out to evaluate energy cost, raw material cost, campaign time, and process mass intensity. Solvent and particle size showed significance as main effects, whereas temperature and time presented significance as interactions. From an industrial and sustainable perspective, ethanol (EtOH) in a 1/20 (w/v) ratio was the best choice since it presented the lowest cost for energy and raw material. It also showed the lowest
Bisphenol A (BPA) is a chemical that is present in many products including water bottles, dental fillings, and sports equipment. BPA can imitate the bodys hormones and can interfere with many bodily functions. Researchers believe that BPA may cause fertility problems and other health issues. Learn more about BPA here.
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EHN.org investigation finds regulatory push to discredit independent evidence of harm while favoring pro-industry science despite significant shortcomings.
TEAC is unspecific for polyphenols nonetheless excel lent linear correlations are already observed amongst TEAC and total phenolic profile employing the FCR assay. Vary ences in cooking system could be the source of inconsistency among the existing research and prior work. Our hypothesis on why we detected no considerable adjust in complete polyphenolics is the fact that steaming may have removed water, consequently preserving the remaining polyphenols within a much more concentrated form. Hence, the continuous polyphenolic concentration throughout the cooking approach is plausible. Discrepancies exist amongst cooking scientific studies and querce tin content. In the present study, quercetin was not mea sured as it was not a key aim on the review and complete polyphenolic concentration was a greater inte rest than concentration of a particular polyphenol.. Never theless, quercetin would be the selleck chemicals key polyphenolic compound located in onion, as a result many studies have measured ...
To refresh organic chemistry-challenged minds, polyphenols are characterized by the presence of multiple phenolic rings (ie, benzene rings with hydroxyl groups). They are produced by plants to defend against ultraviolet radiation or pathogens. Polyphenols are responsible for some of the color, flavor, odor, and bitterness of fruits, vegetables, grains, and such beverages as tea and coffee. They function as antioxidants and have been reported to bestow health benefits, including protection from cardiovascular disease, cancer, infections, and a variety of other conditions ...
Synthesis and Physical Properties of Sterically Congested Cycloalkenes, 1,2-Di-tert-butyl-3,3,5,5-tetramethylcyclopentene and 1,2-Di-tert-butyl-3,3,6,6-tetramethylcyclohexene
Exposure to trace amounts of an estrogenlike ingredient of polycarbonate plastic may increase the risk of diabetes, experiments in mice show.
2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol 95041-90-0 MSDS report, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol MSDS safety technical specifications search, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol safety information specifications ect.