Abdominaler Abszess|Abszess des Abdomens|Abszess des Epiploons|Abszess des Mesenteriums|Abszess des Omentums|Abszess des kleinen Beckens|Akute Bauchfellentzündung|Akute Peritonitis des männlichen Beckens|Akute diffuse Peritonitis|Akute eitrige Peritonitis|Akute eosinophile Peritonitis|Akute subphrenische Peritonitis|Allgemeine Peritonitis|Bakterielle Peritonitis|Bauchhöhlenabszess|Bauchraumabszess|Beckenperitonitis beim Mann|Diaphragmatische Peritonitis|Diffuse Peritonitis a.n.k.|Disseminierte Peritonitis|Eiterung des männlichen Beckens|Eitrige Peritonitis|Empyem im Oberbauch|Extraperitonealabszess|Fibropurulente Peritonitis|Generalisierte Peritonitis|Intraabdominaler Abszess|Intraperitonealer Abszess|K65.0 Akute Peritonitis|Mesenterialer Abszess|Männliche Pelveoperitonitis|Netzabszess|Pankreatische Peritonitis|Pelveoabdominaler Abszess|Pelvikoabdominaler Abszess|Perforierter Peritonealabszess|Peritonealabszess|Peritonealer Beckenabszess beim Mann|Peritonealphlegmone|Peritonitis mit Abszess
Introduction Severe peritonitis belongs among severe diseases with mortality 20-60%. Causes are number of primary surgical diseases (inflammatory acute abdomen syndromes - perforated diverticulitis, perforated tumor, colon ischemia and other) or complications after abdominal surgeries in frequency 12-16%.. Secondary and tertiary peritonitis can be in insult causing system inflammatory response (SIRS) with subsequent sepsis and multi-organ failure; it is serious state of patient who requires long term and costly intensive care and despite of that it often ends with permanent disability. Basic therapy of severe peritonitis is surgical treatment of origin of abdominal sepsis, contamination elimination and prevention of postoperative complications. The insufficient capability to manage postoperative complications (polymorbidity, diabetes, inveterate peritonitis, immunosuppressed patient) is often the cause of organ and mutli-organ failure. In case of primary closure of the abdominal cavity and after ...
Objectives: To determine the association between pre hospital use of proton pump inhibitors and spontaneous bacterial peritonitis in patients presenting with liver cirrhosis. Study Design: Case control study. Setting: Department of Gastroenterology at Liaquat National Hospital Karachi. Period: Six months (From 1st - March-2017 to 31st - August-2017). Material and Methods: There were 120 patients with cirrhosis were included in this study. Sixty patients were cases with spontaneous bacterial peritonitis (SBP) and 60 patients were control without spontaneous bacterial peritonitis. All patients were interviewed for pre hospital intake of PPI (as per operational definition). All the data was entered on predesigned proforma (attached). Results: The average age of the patients was 42.47±9.87 years. Rate of PPI use was significantly higher among cases with SBP (46.7%) as compared to the patients without SBP (23.3%). Conclusion: In conclusion, PPI use (acid suppression) was associated with the ...
INTRODUCTION. Peritonitis is a major complication of peritoneal dialysis. Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus spp., Enterococcus faecalis and Escherichia coli are the most common causative pathogens for peritonitis.1 Guidelines recommend that selection of empiric therapy must cover both gram-positive and gram-negative microorganisms and a fourth-generation cephalosporin is a suitable agent. In addition a first-generation cefalosporin may be used with ceftazidime or aminoglycoside, if cefepime is not available. After causative organism is identified, treatment should be organized according to microorganism.2 Minimum length of therapy is two weeks, for severe infections the recommended treatment duration is three weeks.3 In literature Campylobacter peritonitis has been reported in adult patients. In this report we present the first pediatric case with C. jejuni peritonitis.. CASE REPORT. A 10-year-old boy with end stage renal failure secondary to atypical hemolytic ...
Results: 365 (6%) patients lived 100 km from their nearest PD unit (distant group), while 6183 (94%) lived ,100km (local group). Median time to first peritonitis in distant patients (1.34years, 95% CI 1.07-1.61) was significantly shorter than in local patients (1.68years, 95% CI 1.59-1.77, p=0.001), whilst overall peritonitis rates were higher in distant patients (incidence rate ratio 1.32, 95% CI 1.20-1.46). Living 100 km away from a PD unit was independently associated with a higher risk of S. aureus peritonitis (adjusted odds ratio [OR] 1.64, 95% CI 1.09-2.47). Distant patients with first peritonitis episodes were less likely to be hospitalised (64% vs 73%, p=0.008) and receive antifungal prophylaxis (4% vs 10%, p=0.01), but more likely to receive vancomycin-based antibiotic regimens (52% vs 42%, p,0.001). Using multivariable logistic regression analysis of peritonitis outcomes, distant patients were more likely to be cured with antibiotics alone (OR 1.55, 95% CI 1.03-2.24). All other ...
Mortality of generalized postoperative peritonitis remains high at 22% to 55%. The aim of the present study was to identify prognostic factors by means of univariate and multivariate analysis in a consecutive series of 96 patients. Mortality was 30%. Inability to clear the abdominal infection or to control the septic source, older age, and unconsciousness were significant factors related to mortality in the multivariate analysis. Failure to control the peritoneal infection (15%) was always fatal and correlated with failed septic source control, high Acute Physiology and Chronic Health Evaluation (APACHE) II score, and male gender. Failure to control the septic source (8%) also was always fatal and correlated with high APACHE II score and therapeutic delay. In patients with immediate source control, residual peritonitis occurred in 9% after purulent or biliary peritonitis and in 41% after fecal peritonitis (p = 0.002). In patients without immediate control of the septic source, delayed control ...
Spontaneous bacterial peritonitis (SBP) is the development of a bacterial infection in the peritoneum causing peritonitis, despite the absence of an obvious source for the infection. It occurs almost exclusively in people with portal hypertension (increased pressure over the portal vein), usually as a result of cirrhosis of the liver. It can also occur in patients with nephrotic syndrome. The diagnosis of SBP requires paracentesis (aspiration of fluid with a needle) from the abdominal cavity. If the fluid contains bacteria or large numbers of neutrophil granulocytes (>250 cells/µL) (a type of white blood cells), infection is confirmed and antibiotics are required to avoid complications. In addition to antibiotics, infusions of albumin are usually administered. Signs and symptoms of spontaneous bacterial peritonitis include fevers, chills, nausea, vomiting, abdominal tenderness, and general malaise. Affected individuals may complain of abdominal pain and worsening ascites. Thirteen percent of ...
Spontaneous bacterial peritonitis (SBP) is a major complication of cirrhosis and ascites and is responsible for significant morbidity and mortality, The aim of this work is to determine prognostic factors and scores for SBP-related in-hospital mortality, compare the predictive power of CP, MELD, SOFA and AIMS65scores for the prediction of the mortality also to identify the best score cut-off point. This prospective study included 111 patients (76 males and 35 females) with liver cirrhosis, ascites and spontaneous bacterial peritonitis confirmed by laboratory investigations especially peritoneal fluid study was done. There were statistically significant differences between cirrhotic patients with SBP who survive and who dont survive as regard mental status, hepatorenal syndrome, ALT and AST, serum sodium, MELD score, SOFA score and AMS65 score. MELD score and serum sodium have the most excellent prognostic accuracy for SBP-related in-hospital mortality with p= 0.006 for both of them, by identifying cut
TY - JOUR. T1 - Anti-inflammatory effect of sulodexide during acute peritonitis in rats. AU - Karoń, Jacek. AU - Połubinska, Alicja. AU - Antoniewicz, Artur A.. AU - Sumińska-Jasińska, Katarzyna. AU - Brȩborowicz, Andrzej. PY - 2008/1/1. Y1 - 2008/1/1. N2 - Background/Aims: Peritonitis is one of the complications of peritoneal dialysis. We demonstrate the systemic and intraperitoneal anti-inflammatory action of sulodexide given systemically. Methods: Dialysis was performed in male Wistar rats with acute peritonitis induced by addition of endotoxin to the fluid. Sulodexide (10 mg/kg b.w.) was used acutely as supplement to the dialysis fluid or chronically, during 7 days preceding the study by intramuscular (IM) injection. Results: In rats given IM sulodexide the dialysate cell count was lower by 45% (p , 0.001) versus untreated rats with peritonitis. Dialysate elastase activity in IM sulodexide-treated rats was lower by 22% (p , 0.05) compared to peritonitis. In rats treated with IM ...
The etiology distinguishes between bacterial and abacterial (aseptic, toxic-chemical) peritonitis. The latter develop as a result of irritation of the peritoneum by aggressive non-infectious agents (bile, blood, gastric juice, pancreatic juice, urine, chyleic fluid). Abacterial peritonitis takes a rather rapid microbial character as a result of the attachment of infectious pathogens from the lumen of the digestive tract.. Depending on the nature of the peritoneal effusion, there are serous, fibrinous, hemorrhagic, bile, purulent, fecal, putrefactive peritonitis. According to the clinical course, peritonitis is divided into acute and chronic. Given the prevalence of lesions on the surface of the peritoneum, there are distinguished (local) and diffuse peritonitis. The variants of local peritonitis include subdiaphragmatic, appendicular, subheading, intestinal, pelvic abscesses. About diffuse peritonitis is said when the inflammation of the peritoneum has no tendency to limit and clear boundaries. ...
TY - JOUR. T1 - Do the Y-set and double-bag systems reduce the incidence of CAPD peritonitis?. T2 - A systematic review of randomized controlled trials. AU - Daly, C. D.. AU - Campbell, Marion Kay. AU - Cody, Dorothy June. AU - Vale, Luke David. AU - Donaldson, C.. AU - Wallace, Sheila Ann. AU - Lawrence, P. D.. AU - Khan, I. H.. AU - MacLeod, Alison Murray. AU - Grant, Adrian Maxwell. PY - 2001. Y1 - 2001. N2 - Background. Peritonitis is the most frequent serious complication of continuous ambulatory peritoneal dialysis (CAPD). It has a major influence on the number of patients switching from CAPD to haemodialysis and has probably restricted the wider acceptance and uptake of CAPD as an alternative mode of dialysis. This systematic review sought to determine if modifications of the transfer set (Y-set or double-bag systems) used in CAPD exchanges are associated with a reduction ill peritonitis and an improvement in other relevant outcomes.Methods. Based on a comprehensive search strategy, we ...
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Dezesseis eqüinos adultos foram distribuídos aleatoriamente em 4 grupos (GI, GII, GIII e GIV) constituídos por quatro animais, recebendo cada grupo o seguinte inóculo por via intraperitoneal: GI (100 X 10(7) unidades formadoras de colônia (UFC) de Escherichia coli diluídos em 500 ml de solução salina 0,9% estéril); GII (100 X 10(7) UFC de Bacteroides fragilis diluídos em 500 ml de solução salina 0,9% estéril); GIII (100 X 10(7) UFC de Escherichia coli associados a 100 X 10(7) UFC de Bacteroides fragilis diluídos em 500 ml de solução salina 0,9% estéril); GIV (testemunho - 500 ml de solução salina 0,9% estéril). Leucopenia ocorreu em todos os animais inoculados com bactérias, nas primeiras seis horas após as inoculações. Posteriormente a este período, verificou-se em alguns eqüinos inoculados leucocitose. Os eqüinos inoculados com culturas puras de E. coli ou B. fragilis apresentaram peritonites brandas e autolimitantes, enquanto os inoculados com a associação destas ...
TY - JOUR. T1 - CAPD Peritonitis. T2 - Therapy and Risk of Adhesions. AU - Vas, S.. PY - 1989. Y1 - 1989. N2 - It has been recommended that temporary discon‐ tinuation of CAPD may be of value in clearing a resistant peritonitis. I have been reluctant to "rest" the peritoneum in this setting, however, because I am concerned that inflammatory debris will cause peritoneal adhesions and ultimate failure for this dialysis modality. Is there evidence that this is or isnt an important consideration?. AB - It has been recommended that temporary discon‐ tinuation of CAPD may be of value in clearing a resistant peritonitis. I have been reluctant to "rest" the peritoneum in this setting, however, because I am concerned that inflammatory debris will cause peritoneal adhesions and ultimate failure for this dialysis modality. Is there evidence that this is or isnt an important consideration?. UR - http://www.scopus.com/inward/record.url?scp=84979339584&partnerID=8YFLogxK. UR - ...
海词词典,最权威的学习词典,专业出版acute bacterial peritonitis是什么意思,acute bacterial peritonitis的用法,acute bacterial peritonitis翻译和读音等详细讲解。海词词典:学习变容易,记忆很深刻。
Spontaneous bacterial peritonitis (SBP) is an acute bacterial infection of ascitic fluid. Generally, no source of the infecting agent is easily identifiable, but contamination of dialysate can cause the condition among those receiving peritoneal dialysis (PD).
Gurusamy K, Wilson P, Tsochatzis E. Antibiotic prophylaxis to prevent spontaneous bacterial peritonitis in people with liver cirrhosis: a network meta-analysis. Cochrane Database of Systematic Reviews 2018, Issue 9. Art. No.: CD013125. DOI: 10.1002/14651858. ...
TY - JOUR. T1 - Influence of genetic variations in the SOD1 gene on the development of ascites and spontaneous bacterial peritonitis in decompensated liver cirrhosis. AU - Schwab, Sebastian. AU - Lehmann, Jennifer. AU - Lutz, Philipp. AU - Jansen, Christian. AU - Appenrodt, Beate. AU - Lammert, Frank. AU - Strassburg, Christian P. AU - Spengler, Ulrich. AU - Nischalke, Hans Dieter. AU - Trebicka, Jonel. PY - 2017. Y1 - 2017. N2 - BACKGROUND: The balance between generation and elimination of reactive oxygen species by superoxide dismutase (SOD) is crucially involved in the pathophysiology of liver cirrhosis. Reactive oxygen species damage cells and induce inflammation/fibrosis, but also play a critical role in immune defense from pathogens. As both processes are involved in the development of liver cirrhosis and its complications, genetic variation of the SOD1 gene was investigated. PATIENTS AND METHODS: Two SOD1 single nucleotide polymorphisms (rs1041740 and rs3844942) were analyzed in 49 ...
Probiotic therapy in conjunction with antimicrobial treatment does not improve efficacy in the treatment of spontaneous bacterial peritonitis, as was found in a double-blind, placebo-controlled, rando... more
Antibiotic prophylaxis for patients with risk factors for spontaneous bacterial peritonitis (SBP) include: Known history of SBP: Typically prolonged...
Acute Market Reports.com has announced the addition of Global Spontaneous Bacterial Peritonitis Market Analysis And Segment Forecasts To 2015 Market Research
Background. In acute respiratory distress syndrome or pneumonia, a procoagulant shift is observed in bronchoalveolar lavage fluid (BALF). The effect of a primarily extrapulmonary infection on coagulation and fibrinolysis in the pulmonary compartment is unclear. Methods. In 35 patients, 87 bronchoalveolar lavages were performed on the day of operation for secondary peritonitis (day 0) and on days 2 and 3 after surgery. Two noninfectious control groups were included: subjects undergoing bronchoalveolar lavage after elective surgery (n = 8) and those undergoing long-term mechanical ventilation (n = 10). Results. In BALF from patients with peritonitis, a tissue factor (TF)/factor VIIaâ€"mediated activation of coagulation was shown (high levels of thrombin-antithrombin complexes). Levels of fibrinolysis activators decreased rapidly after day 0, whereas levels of inhibitors increased. The net effect was reduced fibrinolysis (plasminogen activator activity). The sequential comparison of plasma ...
Synonyms for chronic peritonitis in Free Thesaurus. Antonyms for chronic peritonitis. 1 synonym for peritonitis: peritoneal inflammation. What are synonyms for chronic peritonitis?
Recent surgical reports indicate that for patients with secondary bacterial peritonitis, surgeons do not routinely use the identification of the bacterial pathogens and determination of their antimicrobial susceptibilities in choosing antimicrobial therapy. Further, some surgeons advocate abandoning the routine practice of obtaining culture specimens from patients with complicated appendicitis, because the data from the clinical laboratory have not been found to have an impact on postoperative care. We review the rationale for continued surveillance of and implementation of bacteriological data in treatment of secondary peritonitis. We also describe in detail the anaerobic flora of secondary peritonitis, the unique susceptibility patterns of these organisms, and the specific virulence factors of anaerobes, particularly Bacteroides fragilis. The fact that clinical investigations sometimes result in treatment failure when gram-negative anaerobes are resistant to the antimicrobials used or when complete
Doses provided in this table are for patients with normal renal and hepatic function. Click on drug link to go to dosing guidelines. Some antimicrobials are restricted (ID-R). Click on link for guidelines on obtaining authorization.. ...
Peritonitis What is peritonitis? Peritonitis is an infection caused by an inflammation of the lining of the abdominal cavity, known as the peritoneum. The peritoneum, a thin, clear membrane, normally covers all the abdominal organs and the inside walls of the abdomen. What causes peritonitis? Most often, peritonitis is caused by the introduction of an infection from a perforation of the bowel such as a ruptured appendix or diverticulum. Other sources include perforations of the stomach, intestine, gallb...
A diagnosis of peritonitis is based primarily on the clinical manifestations described above. Rigidity (involuntary contraction of the abdominal muscles) is the most specific exam finding for diagnosing peritonitis (+ likelihood ratio: 3.9). If focal peritonitis is detected, further work-up should be done. If diffuse peritonitis is detected, then urgent surgical consultation should be obtained, and may warrant surgery without further investigations. Leukocytosis, hypokalemia, hypernatremia, and acidosis may be present, but they are not specific findings. Abdominal X-rays may reveal dilated, edematous intestines, although such X-rays are mainly useful to look for pneumoperitoneum, an indicator of gastrointestinal perforation. The role of whole-abdomen ultrasound examination is under study and is likely to expand in the future. Computed tomography (CT or CAT scanning) may be useful in differentiating causes of abdominal pain. If reasonable doubt still persists, an exploratory peritoneal lavage or ...
Fungal peritonitis, which was once a rare entity, is becoming increasingly common due to various immunocompromised conditions. Candida species are considered the common cause of fungal peritonitis in most cases. However, at present, other yeasts and filamentous fungi are replacing the dominance of C …
Isolated case reports of peritonitis due to Brucella spp. during peritoneal dialysis (PD) continue to surface in the medical literature. However, the optimal treatment regimen for these patients, in particular with regards to the fate of PD catheter, is still largely unknown. We report a case of brucella peritonitis successfully treated with intraperitoneal administration of amikacin, along with oral rifampicin and doxycycline but without catheter removal. Furthermore, we have reviewed the literature up until present day.
The aim of the study was to assess the usefulness of prognostic scales: ASA (American Society of Anesthesiologist), MPI (Meinheim Peritonitis Index), MOFS (the Multiple Organ Failure Score) and SPI (the Simple Prognostic Index) in the prognosis of the course of disease in patients operated on for peritonitis. Material and methods. The study was conducted in the Clinical Department of General and Oncological Surgery of the Medical University in Łódź between January 2009 to December 2010. During this period 263 patients were operated on for peritonitis. Before surgery all patients were classifed into particular groups according to the above mentioned prognostic scales according to their criteria. Results. There were 29 (11%) deaths. ASA ≥4 (p,0.0001), MPI ,30 (p,0.0001) MOFS ≥2 (p,0.0001), SPI II, III, IV (p,0.0001) were important risk factors of death. Conclusions. 1. ASA, MPI, MOFS and SPI scales are of high signifcance in predicting the outcome in patients operated on for peritonitis. 2. ...
1. Changes in the chemistry of the blood of dogs with experimental bile peritonitis are here reported.. 2. In all animals that died, a bile ascites was found.. 3. Dogs dying of bile peritonitis showed a constant increase in the blood non-protein and urea nitrogen, and a fall in the chlorides.. ...
AIM: To investigate in vitro effects of propofol, midazolam and dexmedetomidine, which are commonly used anaesthesic or sedatives, on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic peritonitis. METHODS: Spontaneous contractions of isolated ileum muscle segments from sham operated rats and those exposed to peritonitis, were studied in vitro. The amplitude and the frequency of spontaneous contractions of ileum muscle segments were studied after adding dexmetetomidine, propofol, and midazolam to the organ bath in a cumulative manner. RESULTS: Both amplitude (85.2 +/- 6.6 vs 47.4 +/- 7.1) and frequency (32.8 +/- 4.6 vs 20.2 +/- 3.9) of spontaneous contractions in ileum smooth muscle segments were decreased significantly in the peritonitis group compared to the control group (P , 0.05). Dexmedetomidine significantly increased the amplitude of spontaneous contractions (85.2 +/- 6.6 vs 152.0 +/- 5.4, P , 0.05) whereas, propofol (85.2 +/- 6.6 vs 49.6 +/- 4.8, ...
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BACKGROUND: The clinical outcome of patients with secondary bacterial peritonitis depends on the production of superoxides involved in bacterial killing and the endogenous level of antioxidants. The prognostic significance of their levels has not pre
A previous study found that an AAAG-rich Oligodeoxynucleotide (ODN), designated as MS19, could lessen the acute lung inflammatory injury (ALII) in mice infected by influenza viruses. Bioinformatics analysis found that MS19 is consensus with the binding site of interferon regulatory factor 5 (IRF5) in the regulatory elements of pro-inflammatory genes. This study established a septic peritonitis model in Institute of Cancer Research (ICR) mice infected with Escherichia coli (E. coli), and found that MS19 prolonged the survival of the mice and down-regulated the expression of inducible nitric oxide synthase (iNOS), interleukin-6 (IL-6), and tumor necrosis factor α (TNF-α). In cultured RAW264.7 cells, MS19 significantly reduced the expression of iNOS, IRF5, IL-6, and TNF-α and inhibited the nuclear translocation of IRF5. This data may provide a new insight for understanding how MS19 reduces the excessive inflammatory responses in sepsis.
INTRODUCTION: Spontaneous fungal peritonitis (SFP) is an infection of ascitic fluid occurring in cirrhotic patients. SFP prevalence varies from 0% to 41% of patients with spontaneous peritonitis (SP) and a positive ascitic fluid culture. Cirrhotic patients with SFP who fail to show improvement with empirical antibiotic therapy, before the identification of the fungal pathogen, have high mortality (89.5-100%). Although the weight of the disease is so dramatic, more recent guidelines on infections in cirrhosis do not consider SFP management. The aim of this meta-analysis was to investigate the association between hospitalization (at least 48-72 hours after admission) and risk of SFP ...
BACKGROUND: Refractory peritonitis is defined as failure of clearance of peritoneal fluid despite 5 days of appropriate antibiotic therapy. Catheter removal decreases morbidity and mortality. Data on the outcomes of refractory peritonitis and of reinitiation of peritoneal dialysis (PD) in this group of patients are sparse. The present study analyzed etiology, outcomes, and prognostic factors of refractory peritonitis as well as survival of the reinitiation of the technique. METHODS: This was a single-center retrospective study that included 90 patients of refractory continuous ambulatory PD (CAPD) peritonitis at a tertiary care center in North India ...
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Peritonitis és la inflamació aguda o crònica, generalitzada o focal, de la membrana del peritoneu. Aquesta inflamació pot ser provocada espontàniament per bacteris (peritonitis bacteriana primària o dorigen extra-abdominal)[1] o bé ser secundària a un traumatisme directe -moltes vegades penetrant- a la zona de labdomen,[2] per acció del suc gàstric i les sals biliars. Adesiara, el seu origen és la ingesta dobjectes de naturalesa molt dispar,[3][4] la febre tifoide,[5] els bezoars,[6] lesquistosomiasi[7] la tuberculosi[8] la diverticulosi,[9] la sarcoïdosi,[10] la cistitis gangrenosa,[11] la ruptura vesical,[12] la ruptura duna hèrnia de Richter[13] o la perforació duna úlcera pèptica.[14] El terme peritonitis terciària es fa servir per referir-se a una inflamació peritoneal detiologia infecciosa amb afectació sistèmica que persisteix 48 h després duna intervenció quirúrgica practicada satisfactòriament i en condicions adequades amb el propòsit de tractar una ...
Bacterial peritonitis is an abdominal infection that involves the peritoneum. The infection requires hospitalization and antibiotic treatment.
A recent AJKD article by Kitrungphaiboon et al explored whether cefepime monotherapy, as an empirical treatment of CAPD-associated peritonitis, has noninferior efficacy for the resolution of peritonitis at day 10 (primary treatment response) compared to the conventional combination regimen of cefazolin plus ceftazidime. AJKDs Social Media Editor, Timothy Yau @Maximal_Change, recorded an interview with his ID…
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肝硬化(德語:Zirrhose,法语:cirrhose,西班牙語:cirrosis,英语:cirrhosis,/sɪˈroʊsɪs/)指的是肝臟因長期受到傷害,導致最後無法正常運作。肝硬化是漫長的過程,在早期通常沒有症狀,隨著疾病的發展,患者可能開始感到容易疲倦、虛弱、下肢水腫、皮膚泛黃、容易瘀青、產生腹水、或是在皮膚上見到如蜘蛛般延展的血管(英语:Spider angioma)等等。腹水一旦發生就可能發生自發性細菌腹膜炎(英语:Spontaneous bacterial peritonitis)。其他與肝硬化相關的疾病與症狀還有肝性腦病變(英语:Hepatic encephalopathy)、由於曲張的食道靜脈(英语:Esophageal varices)破裂而造成的吐血、肝肾综合症、以及肝癌等[5]。肝腦病變可能造成患者意識混亂甚至陷入昏迷[1]。 ...
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Canadian Journal of Gastroenterology and Hepatology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of gastroenterology and hepatology. The journal welcomes submissions related to the medical, surgical, pathological, biochemical, and physiological aspects of these subject areas.
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Principal Investigator:INAGAKI Yoshinori, Project Period (FY):1995 - 1997, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Digestive surgery
Culture-negative neutrophilic ascites (CNNA) has clinical, prognostic, and therapeutic characteristics similar to spontaneous bacterial peritonitis (SBP) and should be treated in a similar fashion. Patients with monomicrobial non-neutrophilicbacterascites (MNB) typically respond similar to CNNA and SBP if the patient is symptomatic; asymptomatic patients usually do not need antibiotics and observation is appropriate, but consideration of TB should be entertained ...
Primary (spontaneous) bacterial peritonitis - Occurs without an apparent source of contamination and is thought to be secondary to bacterial translocation across the bowel. It is most commonly found in patients with underlying cirrhosis and ascites, but may be found in patients with congestive heart failure, systemic lupus erythematosus, chronic viral hepatitis, or acute viral hepatitis. Presentation can be subtle, and up to 30% of patients may be asymptomatic. Fever is common, but presentation can be marked by altered mental status or abdominal pain in those with cirrhosis. This infection is often paucibacillary, and culture is not uncommonly negative. When an organism is identified, common organisms include Escherichia coli, streptococci, enterococci, and pneumococci ...
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