Multilocular peritoneal inclusion cysts (MPICs) are most commonly found in women of reproductive years and involve the abdomen, pelvis, and retroperitoneum. It is commonly thought that these cysts are due to an inflammatory reaction. Patients usually present with chronic abdominal or pelvic pain and are diagnosed by ultrasound or CT scan. Although there are experimental medical treatment options surgical excision remains the current recommended primary therapy for symptomatic disease. The following case describes a pregnant female with rare MPIC involving the spleen and peritoneum. Biological behavior of MPIC and current therapy options are also discussed ...
Abstract. Objectives: Peritoneal inclusion cyst (PIC) is defined as a fluid-filled mesothelial-lined cysts of the pelvis and it is most frequently encountered in women of reproductive age. The treatment options are observation, hormonal management, imaging-guided aspiration, image-guided sclerotherapy and surgical excision. The objective of this study is to compare between the laparoscopic and laparotomic surgery for the treatment of PIC.. Methods: Thirty-five patients with laparoscopy and forty-eight patients with laparotomy were included in the study. We compared the perioperative and postoperative data, the complications and the recurrence between the two groups.. Results: There was a significantly reduced mean length of the hospital stay, estimated blood loss and complication rate in the laparoscopic group as compared to that of the laparotomic group (P=0.037, P=0.047 and P=0.037 respectively). There was also no statistical difference of recurrence rate between thelaparoscopic and ...
Peritoneal adhesions occur in up to 93% of adults after peritoneal trauma during surgery. Most adhesions are asymptomatic but can cause female infertility, small bowel obstruction (SBO) and chronic abdominal pain. Adhesion prophylaxis is needed to reduce the significant morbidity and increased health care costs resulting from peritoneal adhesions. This thesis aims to establish a relevant and reproducible experimental adhesion model to simultaneously study the healing processs and adhesion formation and later to examine whether carbazate-activated polyvinyl alcohol (PVAC), an aldehyde-carbonyl scavenger, can reduce adhesion formation or not; and, in a long-term follow-up, to investigate the incidence of and identify risk factors for adhesive SBO requiring surgical treatment after laparotomy during infancy and to survey the prevalence of self-reported chronic abdominal pain and female infertility. Male Sprague-Dawley rats were subjected to laparotomy, cecal abrasion, and construction of a small ...
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Peritoneal adhesion formation is a common consequence of any operation or intra-abdominal inflammatory process (eg, pelvic inflammatory disease [PID], diverticulitis, spontaneous bacterial peritonitis). It is estimated that intra-abdominal adhesions develop in 90-95% of patients after surgery.
Another focus of our research is the characterization of endometriosis-associated smooth muscle cells in various forms of endometriosis. We could demonstrate oxytocin receptor (OTR)-positive muscle cells in peritoneal endometriotic lesions. In further studies, we could reveal data supporting a metaplastic origin of these muscle cells. This is particularly important for understanding of the pathogenesis of this disease and pain sensations that could possibly be caused by contraction of peritoneal muscles can be suggested. The detection of morphological changes in the structure of the myometrial wall in adenomyosis highlights the contractile dysfunction in patients with adenomyosis. Also interesting is the observation of a transition of the basal layer into the adjacent myometrium in women with adenomyosis compared to patients without adenomyosis and supports the current theory of rupture due to a basal hyperperistalsis. The OTR is involved in the uterine peristalsis and thus represents a possible ...
TY - JOUR. T1 - Adenovirus-mediated expression of cyclooxygenase-2 antisense reverse abnormal genetic profile of human adhesion fibroblasts. AU - Saed, Ghassan M.. AU - Al-Hendy, Ayman. AU - Salama, Salama A.. AU - Diamond, Michael P.. PY - 2008/5/1. Y1 - 2008/5/1. N2 - Objective: To determine the effects of blocking the translation of cyclooxygenase-2 (COX-2) mRNA on the mRNA levels of type I collagen, type III collagen, fibronectin, and transforming growth factor-beta (TGF-β1) in fibroblasts obtained from normal peritoneal and adhesion tissues. Design: Prospective experimental study. Setting: University medical center. Patient(s): Fibroblasts established from peritoneal and adhesion tissue of the same patients. Intervention(s): Adenovirus with COX-2 treatment of the primary cultured fibroblasts. Main Outcome Measure(s): Fibroblasts of normal peritoneal and adhesion tissues were isolated from the same patients. Adhesion and normal peritoneal fibroblasts were transfected with an adenovirus ...
The recommended treatment of epithelial ovarian cancer (EOC) includes optimal surgical debulking to , 1 cm residual disease, followed by a combination of intraperitoneal (IP) and intravenous (IV) chemotherapy for at least 6 cycles. Serous EOC is known to spread transperitoneally and is often diffusely disseminated within the peritoneal cavity. It is believed that IP therapy via direct contact is effective in treating such small intraperitoneal implants. What is not known is whether IP therapy is evenly distributed in individuals and to what degree adhesions and formation of scar tissue prevents the even distribution of chemotherapy within the belly, potentially impacting efficacy. Few studies have addressed the question of adhesions and intraperitoneal therapy in general, and there have been no studies specifically in ovarian cancer utilizing current guidelines. Efficacy has been proven for IP/IV therapy over IV alone but the range of survival within the IP group may be secondary to tumor ...
This is purely my conjecture based on my readings. The literature refers to peritoneal endometriosis, ovarian endometriosis, and deep infiltrating endometriosis. Current theory points to defects when our pelvic organs are developed (Mullerianosis) that leave stem cells in the wrong place. This might also explain why other mullerian disorders such as adenomyosis are frequently seen in endometriosis patients as well. These stem cells are acted upon by hormones (puberty) to develop as glands and stroma and begin the process of making nerves and blood vessels to support itself - as any good stem cell should. However that tissue should not be in those wrong sites and an inflammatory response happens. Factors from the environment (food, physical activity, stress, etc) play a role in presentation of illness. This is why diet etc might affect symptoms but will not rid the person of the lesions. The different locations of stem cells left behind might influence how they are acted upon by hormones and ...
Laser Laparoscopic surgery is performed for the safe and accurate sublimation of endometriosis foci, either for mild damages of peritoneal endometriosis, or cases of extensive endometriosis and chocolate cysts. The accuracy of the method allows the selective destruction of the damage and prevents the neighboring vital organs and the healthy ovarian tissue.. Its application improves the probability of spontaneous conception and the success rate in assisted reproduction.. See more ...
Background Postoperative adhesions constitute a substantial clinical problem at hand surgery. for PXL01 placebo group, p?=?0.016 in PPAS). The percentage of sufferers with exceptional/great digit mobility was higher in the PXL01 group (61% 38%, p?=?0.0499 in PPAS). Regularly, the PXL01 group provided improved tip-to-crease length (5.0 15.5 mm for PXL01 placebo group, p?=?0.048 in PPAS). Sensory evaluation demonstrated that more sufferers in the PXL01 group sensed the thinnest monofilaments (FAS: 74% 35%, p?=?0.021; PPAS: 76% 35%, p?=?0.016). At a year post-surgery, more sufferers in the placebo group had been considered to reap the benefits of tenolysis (30% 12%, p?=?0.086 in PPAS). The procedure was secure, well tolerated, and didnt increase the price of tendon rupture. Conclusions Treatment with PXL01 in sodium hyaluronate increases hands recovery after flexor tendon fix surgery. Additional scientific trials are warranted to look for Vilazodone the many effective health insurance and dose ...
Severity of adhesions at seven predefined sites (pericardial or retrosternal, inferior or diaphragmatic region, right lateral or arterial region, region around great vessels). Severity of adhesions is graded as 0 = no adhesions, 1 = filmy and avascular, 2 = requiring blunt dissection, 3 = requiring sharp dissection, 4 = requiring extensive sharp dissection. Adhesion scores for each patient will be derived from the sum of adhesion severity scores at each site, from 0 (no adhesions) to 28 (cohesive adhesions at all sites ...
TY - JOUR. T1 - CAPD Peritonitis. T2 - Therapy and Risk of Adhesions. AU - Vas, S.. PY - 1989. Y1 - 1989. N2 - It has been recommended that temporary discon‐ tinuation of CAPD may be of value in clearing a resistant peritonitis. I have been reluctant to "rest" the peritoneum in this setting, however, because I am concerned that inflammatory debris will cause peritoneal adhesions and ultimate failure for this dialysis modality. Is there evidence that this is or isnt an important consideration?. AB - It has been recommended that temporary discon‐ tinuation of CAPD may be of value in clearing a resistant peritonitis. I have been reluctant to "rest" the peritoneum in this setting, however, because I am concerned that inflammatory debris will cause peritoneal adhesions and ultimate failure for this dialysis modality. Is there evidence that this is or isnt an important consideration?. UR - http://www.scopus.com/inward/record.url?scp=84979339584&partnerID=8YFLogxK. UR - ...
TY - JOUR. T1 - Primary omental infarct. T2 - conservative vs operative management in the era of ultrasound, computerized tomography, and laparoscopy. AU - Nubi, Ayodeji O.. AU - McBride, Whitney. AU - Stringel, Gustavo. PY - 2009/5/1. Y1 - 2009/5/1. N2 - Purpose: Primary omental infarct is a rare condition in children. The preoperative diagnosis can be accurately accomplished using ultrasound (US) and computerized tomography (CT). This study aimed to elucidate the efficacy of conservative vs operative management. Methods: Cases of omental infarction in children diagnosed preoperatively in our institution since laparoscopy became the standard of care were reviewed. Results: Ten cases of omental infarction in children were treated. There were 6 males and 4 females (age, 5-14 years). The diagnosis was made preoperatively by CT in all cases; in 2 cases, US was also diagnostic. Conservative nonoperative management was successful in 4 cases, and laparoscopic omentectomy and appendectomy done in the ...
OP28 The complement component C3 is expressed by the endometrial ectopic tissue and is involved in the endometriotic lesion formation C. Agostinis 1, G. Zito 1, D. De Santo1, R. Vidergar2, O. Radillo 1, F. Bossi 1, S. Zorzet2, G. Ricci 1, R. Bulla 2 1 Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy 2 Department of Life Sciences, University of Trieste, Trieste, Italy E-mail address: [email protected] (C. Agostinis). Background: The complement (C) system is one of the major components of humoral innate immunity, acting as the first lines of defence against microbes. The principal roles of C system are the opsonization and lysis of pathogens, but new roles in inflammatory and immunological processes are emerging. It is involved in numerous inflammatory diseases, such as SLE, PNH and endometriosis (EM). Several groups have been demonstrated that the glandular epithelial cells found in endometriotic implants produce and secrete the C component C3. The aim ...
The peritoneum is a serous membrane that consists of two layers: parietal peritoneum and visceral peritoneum (Figure 8-1A-C). The parietal peritoneum lines the internal walls of the abdominal cavity, forming a closed sac known as the peritoneal cavity. The peritoneal cavity is completely closed in males. In females, the peritoneal cavity has two openings where the uterine tubes, uterus, and vagina provide a passage to the outside. The parietal peritoneum reflects off of the posterior abdominal wall, forming a fused, double layer of peritoneum surrounding the blood vessels, nerves, and lymphatics to abdominal organs. This double layer of peritoneum, known as the mesentery, suspends the jejunum and ileum from the posterior abdominal wall. The peritoneum that surrounds the gut tube is called the visceral peritoneum. The peritoneal membranes produce a serous fluid that lubricates the peritoneal surfaces, enabling the intraperitoneal organs to slide across one another with minimal friction. ...
Endoscopic methods (laparoscopy and hysteroscopy) are valuable tools in the diagnosis and treatment of infertility. Endoscopic (hysteroscopic-laparoscopic) surgery, by widening its range of application, has evolved into the treatment of choice for infertility cases, while it tends to minimize the indications for traditional laparotomy.. Hysteroscopy allows us to view the cavity of the uterus, i.e. the location that will receive the developing embryo and will support its development. Laparoscopy is useful for examining the internal female reproductive organs (i.e. uterus, fallopian tubes and ovaries). Salpingoscopy allows us to view the intraluminal portion of the uterine tubes, although this method was not widely accepted, it is rarely used and is not part of everyday clinical practice.. Some pathological conditions of female genital organs cannot be diagnosed with any other method but by hysteroscopy (e.g. endomitritis) or laparoscopy (e.g. peritoneal endometriosis or adhesions). It is possible ...
We report the case of an omental cyst, a rare type of abdominal cystic lesion that is difficult to diagnose preoperatively. A 43-year-old man with no clinical symptoms was admitted to our hospital for
Endometriosis is a chronic, inflammatory disease characterized by the growth of endometrial tissue in aberrant locations outside the uterus. Neoangiogenesis or establishment of new blood supply is one of the fundamental requirements of endometriotic lesion survival in the peritoneal cavity. IL-17A is emerging as a potent angiogenic and proinflammatory cytokine involved in the pathophysiology of several chronic inflammatory diseases such as rheumatoid arthritis and psoriasis. However, sparse information is available in the context of endometriosis. In this study, we demonstrate the potential importance of IL-17A in the pathogenesis and pathophysiology of endometriosis. The data show a differential expression of IL-17A in human ectopic endometriotic lesions and matched eutopic endometrium from women with endometriosis. Importantly, surgical removal of lesions resulted in significantly reduced plasma IL-17A concentrations. Immunohistochemistry revealed localization of IL-17A primarily in the stroma ...
Background. The use of locally administered agents to prevent intraperitoneal adhesions is a popular research topic. The presumed effects of these agents on tissue matrix limit their use. ...
Intestinal adhesion after abdominal surgery is a continuous state of fibrosis and inflammation that concomitantly facilitates the progression of a variety of complications, such as chronic abdominopelvic discomfort, pain, and infertility. Berberine has recently become a useful anti-inflammatory drug for cardiovascular, endocrine, and intestinal disorders, because of its antitumor and antilipase effects (Jeong et al., 2009; Jiang et al., 2011; Meng et al., 2012; Yao et al., 2013). Here, we identified berberine as an antiadhesion agent that effectively protects against postabdominal surgery adhesion and inflammation, with several lines of evidence including reduced adhesion scores from direct assessment of adhesions, histopathology measurement of lymphocytes and vascular proliferation, decreased circulating concentration of ICAM-1, downregulated expression levels and secretion of various proinflammatory cytokines in both serum and cecum, and suppression of TAK1, JNK, and NF-κB signaling.. ICAM-1 ...
Full text of Master Techniques in Colon and Rectal Surgery : Abdominal Operations 1st ed. (2012) Editor: Wexner, Steven D.; Fleshman, James W. is available through [email protected] For USC users only. Requires USC network connection. Allows limited number of simultaneous connections.. Usage Restrictions ...
MRI may provide useful information for preoperative planning relating to pelvic adhesions, according to a multidisciplinary team of radiologists and gynecolo...
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Soon this site will allow access to centers specialized in therapy of pleural and/or peritoneal diseases worldwide.. Pleural and/or peritoneal diseases might be life-threatening. ISSPP members are most qualified to treat these diseases. ISSPP can connect you with a specialized center in your country to receive:. ...
What is endometriosis? Endometriosis is a gynecological condition in which endometrial tissue is found outside the uterus. This is mostly found in the peritoneum & etc.
Semantic Scholar extracted view of [The lymph- and blood vessels of the peritoneum parietale of man and its construction]. by I J Juldaschew
... - Surgical Treatment of Intestinal Endometriosis: Outcomes of Three dor acíclica, disquezia, sangramento uterino anormal, infertilidade. NOV Endometriose e
Bowel obstruction is a condition which has been known for many years. As time goes by, the problem is still often encountered at surgical emergency rooms. More than 20% of emergency surgical interventions are performed because of symptoms of digestive tract obstruction with the disease mostly situated in the small bowel. Rates of causative factors of the disease have changed over recent years and there have been increasingly more cases of small bowel obstruction caused by peritoneal adhesions, i.e., adhesive small bowel obstruction (ASBO).The aim of the study to analyse the reasons and incidence of adhesive small bowel obstruction during two periods of time (1990-1995 and 2005-2010).Material and methods. We performed a retrospective analysis of medical records of patients hospitalized at the 1st Department of General Surgery and Surgical Oncology of the Provincial Polyclinic Hospital in Płock between 1990 and 1995. The outcomes were compared with another period of 2005-2010.Results. We found ...
TY - JOUR. T1 - Global Transcriptome Abnormalities of the Eutopic Endometrium from Women with Adenomyosis. AU - Herndon, Christopher N.. AU - Aghajanova, Lusine. AU - Balayan, Shaina. AU - Erikson, David. AU - Barragan, Fatima. AU - Goldfien, Gabriel. AU - Vo, Kim Chi. AU - Hawkins, Shannon. AU - Giudice, Linda C.. PY - 2016/10/1. Y1 - 2016/10/1. N2 - Objective: Adenomyosis is a clinical disorder defined by the presence of endometrial glands and stroma within the myometrium, the pathogenesis of which is poorly understood. We postulate that dysregulation of genes and pathways in eutopic endometrium may predispose to ectopic implantation. No study, to our knowledge, has examined the global transcriptome of isolated eutopic endometrium from women with clinically significant adenomyosis. Design: Laboratory-based study with full institutional review board approval and consents. Material and Methods: Endometrial sampling was performed on hysterectomy specimens (proliferative phase) from symptomatic ...
It was concluded that visceral manipulation has a positive benefit not only of lysing adhesions, but also of preventing them as well. Physiologically, visceral manipulation may decrease the formation of adhesions because it causes disruption of fibrin and inhibits fibroblast migration to the injured area. Additionally, the increase in fluid movement due to manipulation could have caused increased metabolite exchange and, as a result, fibrinolysis. Rats were not sedated during manipulation, and the force needed to mobilize abdominal contents did not elicit flinching or biting. In fact, the investigators noted during manipulation that the rats became calm and allowed deep palpation and treatment. The investigators suggested that visceral manipulation should be used immediately after a surgical procedure because adhesion formation is greatest at this time. Furthermore, the rats in the preventive group were noted to have increased signs of healing, including a general observation of overall improved ...
Endometriosis is defined as the presence of endometrial-like endometrial cells, glands and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but the estimates range from 2-10 % of women of reproductive age, to 50 % of infertile women. Its etiopathogenesis of endometriosis still remains controversial: immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.Endometriosis can cause several symptoms and signs, including acute and chronic pelvic pain, dysmenorrhea, dyspareunia, abnormal vaginal bleeding, infertility/sterility and, in the severe stage, gastrointestinal and urological symptoms. Three main clinical presentations have been described: peritoneal endometriosis, endometriotic ovarian cysts (i.e., endometriomas), and deeply infiltrating endometriosis (DIE) .The latter is considered the most aggressive presentation of endometriosis
The peritoneum is one continuous sheet, forming two layers and a potential space between them: the peritoneal cavity.. The outer layer, the parietal peritoneum, is attached to the abdominal wall and the pelvic walls.[1] The tunica vaginalis, the serous membrane covering the male testis, is derived from the vaginal process, an outpouching of the parietal peritoneum.. The inner layer, the visceral peritoneum, is wrapped around the visceral organs, located inside the intraperitoneal space for protection. It is thinner than the parietal peritoneum. The mesentery is a double layer of visceral peritoneum that attaches to the gastrointestinal tract. There are often blood vessels, nerves, and other structures between these layers. The space between these two layers is technically outside of the peritoneal sac, and thus not in the peritoneal cavity.. The potential space between these two layers is the peritoneal cavity, filled with a small amount (about 50 mL) of slippery serous fluid that allows the two ...
BACKGROUND/AIMS: Cyclosporin A (CsA) stimulates the development of fibrosis. We investigated whether CsA contributes to peritoneal alterations induced by long-term exposure to dialysis solutions. METHODS: Ten rats received peritoneal infusion of dial
The mechanisms underlying peritoneal dissemination of ovarian carcinoma are poorly understood. Ovarian carcinoma is a malignancy with an exceptionally high mortality rate (1), largely due to the lack of effective antimetastatic treatment approaches. A more detailed understanding of the mechanisms underlying the formation and development of EOC metastases could offer insights into how late stages of this disease might be effectively targeted. Proteins that are presented on the cell surface have consistently been considered attractive molecular targets for disease treatment. Our data suggest that a member of GPCR family, the chemokine fractalkine receptor, functions to support the prometastatic properties of EOC cells, which include migration, peritoneal adhesion, and proliferation. In addition, the fractalkine chemokine can support cell proliferation through another receptor, EGFR. Our data support the hypothesis that multiple types of ovarian carcinoma rely on fractalkine signaling for disease ...
Results: The mean age of women was 32.22±6.91. The mean serum CA-125 level was 49.93±4.30 U/mL. There was a significant correlation between the endometriosis stage, lesion size, adhesion score and preoperative CA-125 plasma concentration. However, we did not found significant differences in age, marital status, patients complaints, and pelvic pain associated to Ca125 serum level. The suggested preoperative serum cut-off levels in premenopausal and postmenopausal patients were 37 U/ml and 35 U/ml, respectively ...
Aims: It is generally considered that an unequivocal histological diagnosis of endometriosis requires the presence of endometrioid-type glands and endometrioid-type stroma. However, small nodules or plaques of endometrioid-type stroma without glands have been noticed by the authors in repeated peritoneal biopsies performed for suspected endometriosis. These are often, but not always, accompanied by typical endometriosis with glands. This form of endometriosis has been previously referred to as stromal or micronodular stromal endometriosis. However, there has been little reference to this condition in the literature.. Methods: In this study, there was a review of a large series (n = 274) of peritoneal biopsies with a diagnosis of endometriosis with a view to ascertaining the frequency of stromal endometriosis.. Results: Stromal endometriosis, characterised histologically by small microscopic nodules or plaques of endometrioid-type stroma, sometimes with a whorled pattern and prominent vascularity ...
Endometriosis is a very common gynecological disorder affecting women in their reproductive years. It is reported that patients with endometriosis have reduced…
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Abstract.--We describe a new species of Centrolenidae, Cochranella erminea n. sp., from the Amazonian lowlands of the department of Junín, Peru. This new species is diagnosed from other centrolenids by having vomerine teeth, bones green in life, parietal peritoneum and pericardium white, all other visceral peritonea clear, dorsum in life viridian to olive green with abundant enameled (bright white) flecks/spots on flat warts, and scattered larger dark blue spots on warts, extensive webbing between outer fingers, snout in profile slightly sloping anteroventraly, and rounded in dorsal view, iris in life between light grey and slate gray with fine darker gray reticulations. We also present new information on the distribution of C. truebae and C. ametarsia in Peru ...
A spiral CECT in a 64-year-old female patient with a pelvic mass. Ascites is present and the parietal peritoneum is irregularly thickened (arrowheads) by deposits of tumour. Ovarian primary carcinoma was proved ...
Synonyms for peritoneums in Free Thesaurus. Antonyms for peritoneums. 4 words related to peritoneum: mesentery, omentum, serosa, serous membrane. What are synonyms for peritoneums?
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Endometriosis treatment by Dr. David Redwine at St. Charles Medical Center. Our internationally recognized endometriosis research, treatment approach and positive long-term outcomes help women in their search for better health and relief from the physical and emotional pain of endometriosis ...
According to the Endometriosis Foundation of America, it is not exactly clear what causes the disorder. What research does indicate is that it is not contagious, and there may be a genetic aspect to it that makes it more likely for women to have endometriosis if a close female relative has it. Interestingly, research has also indicated that endometriosis can be present during a babys development. The disorder is then triggered at the age of puberty ...