Background The residual Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) Score is an objective measure of the degree and complexity of residual stenosis after percutaneous coronary intervention (PCI). Methods and Results In the randomized PCI cohort of the SYNTAX Trial (n=903), the baseline and residual SYNTAX Scores were calculated. Subjects with a residual SYNTAX Score of 0 were defined as having undergone complete revascularization (CR), and a residual SYNTAX Score ,0 as incomplete revascularization (ICR). Five-year clinical outcomes were stratified by CR and ICR (tertiles of the residual SYNTAX Score: ,0-4, ,4-8, and ,8). In the PCI cohort, the mean baseline and residual SYNTAX Scores were 28.4 +/- 11.5 and 4.5 +/- 6.9, respectively. The mean SYNTAX Score (representative of the burden of disease removed by PCI) was 23.8 +/- 10.9. The residual SYNTAX Score was distributed as follows: CR, 0 (n=386, 42.7%); ICR, ,0 to 4 (n=184, 20.4%), ,4 to 8 (n=167, ...

Successful percutaneous coronary intervention during cardiac arrest with use of an automated chest compression device: a case report Berglind Libungan, Christian Dworeck, Elmir OmerovicDepartment of Cardiology, Sahlgrenska University Hospital, Göteborg, SwedenAbstract: Ventricular tachycardia or fibrillation (VT/VF) in patients with ST-elevation myocardial infarction (STEMI) is associated with poor prognosis. Performing manual chest compressions is a serious obstacle for treatment with percutaneous coronary intervention (PCI). Here we introduce a case with refractory VT/VF where the patient was successfully treated with an automated chest compression device, which made revascularization with PCI possible.Keywords: PCI, LUCAS, STEMI, automatic chest compressions, ventricular fibrillation, mechanical CPR

A large proportion of patients with coronary artery disease treated with elective percutaneous coronary intervention have high residual platelet reactivity1 and endothelial dysfunction, which might represent the link to the occurrence of ischemic events.2 This is even more the case for patients with diabetes mellitus, in whom more potent P2Y12 receptor inhibitors have been proposed with promising results in terms of reduced platelet reactivity.3 Nevertheless, whether this enhanced platelet inhibition alsomight be beneficial to the endothelial function is yet unknown.. CLOTILDIA (Clopidogrel High Dose Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients)4 was a single-center, prospective, randomized, open label, crossover study, enrolling patients with type2 diabetes mellitus and stable coronary artery disease treated with percutaneous coronary intervention and drug-eluting stent implantation. Patients were recruited at least 1month after percutaneous coronary intervention ...

BACKGROUND: Incomplete revascularisation is common after percutaneous coronary intervention and is associated with increased mortality and adverse cardiovascular events. We aimed to assess whether adjunctive anti-ischaemic pharmacotherapy with ranolazine would improve the prognosis of patients with incomplete revascularisation after percutaneous coronary intervention.. METHODS: We performed this multicentre, randomised, parallel-group, double-blind, placebo-controlled, event-driven trial at 245 centres in 15 countries in Europe, Israel, Russia, and the USA. Patients (aged ≥18 years) with a history of chronic angina with incomplete revascularisation after percutaneous coronary intervention (defined as one or more lesions with ≥50% diameter stenosis in a coronary artery ≥2 mm diameter) were randomly assigned (1:1), via an interactive web-based block randomisation system (block sizes of ten), to receive either twice-daily oral ranolazine 1000 mg or matching placebo. Randomisation was ...

Pre-order Price Guarantee. Details Manual of Percutaneous Coronary Interventions: A Step by Step Approach is a practical, easy to read reference guide on how to perform percutaneous coronary intervention in non-CTO lesions. Written by recognized experts in the field, this reference compiles the necessary steps, lists pitfalls to watch out for, and provides tactics on troubleshooting percutaneous coronary interventions. Written to bring a practical and easy to read approach, this book is perfect for interventional cardiologists, interventional and general cardiology fellows, cardiology researchers, physicians, cardiac catheterization laboratory personnel, technical staff, industry professionals and anyone interested in understanding the cutting-edge and rapidly evolving field of coronary PCI.. ...

Find the best percutaneous coronary intervention doctors in Mumbai. Get guidance from medical experts to select percutaneous coronary intervention specialist in Mumbai from trusted hospitals - credihealth.com

Background The efficacy and safety of ticagrelor following percutaneous coronary intervention for patients with acute coronary syndrome remains unclear. This study sought to evaluate clinical outcomes of ticagrelor as part of dual-antiplatelet treatment for these patients. Methods PubMed, MEDLINE, Embase, and other Internet sources were searched for eligible citations. The primary end point was major adverse cardiovascular and cerebrovascular events, consisting of cardiovascular death, myocardial infarction, and stroke. The secondary end point was the occurrence of definite/probable stent thrombosis (ST). The risk of bleeding was chosen to be the safety end point. Results Eleven clinical trials - six randomized trials and five observational trials - were finally analyzed. A tendency toward reduction in the risk of major adverse cardiovascular and cerebrovascular events was observed only with respect to ticagrelor (OR 0.83, 95% CI 0.66-1.03; P=0

Obesity is an independent risk factor for coronary disease and is prevalent among patients who undergo percutaneous coronary intervention (PCI). The significance of cardiac disease is often underestimated by patients who undergo PCI, and therefore they are more reticent in modifying their cardiac risk factors such as obesity following PCI. This issue is particularly problematic for rural populations, given that weight reduction specific programs are often not available in rural communities. The overall goal of this pilot study is to evaluate a 12 week cognitive behavioral intervention for weight reduction of overweight or obese PCI patients who participate in a rural cardiac rehabilitation (CR) program. The Maximizing Outcomes Needed After Percutaneous Coronary Intervention (PCI) Using Weight Management (MOMENTUM) intervention is comprised of 6 modules, totaling 52 daily sessions promoting weight reduction, and 4 coaching sessions over the duration of the 12 week MOMENTUM intervention. The ...

Aims: We aimed to investigate whether thrombus aspiration could preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). Methods and re

Methods and Results-The Minneapolis Heart Institutes Level 1 Regional ST-Segment-Elevation Myocardial Infarction program is designed to facilitate emergent transfer for PCI in patients with ST-segment-elevation myocardial infarction from 31 rural and community hospitals. To determine the effect of emergent transfer, questionnaires were given to 152 patients and their families who survived to hospital discharge with a 65.8% response rate (mean age, 63.9 years; 29% women). Ninety-five percent of patients felt the reasons and process of transfer were well explained, and 97% felt transfer for care was necessary. Despite this, 15% of patients would have preferred to stay in their local hospital. The majority of the families felt the transfer process (88%) and family members condition (94%) were well explained. Although 99% felt it was necessary for their family member to be transferred for specialized care, 11% of families still would have preferred that their family members remain at the local ...

This study assessed long-term clinical outcomes in diabetes mellitus patients following percutaneous coronary intervention with a second-generation drug-eluting

TY - JOUR. T1 - Trends, predictors, and outcomes of cerebrovascular events related to percutaneous coronary intervention. T2 - A 16-year single-center experience. AU - Hoffman, Scott J.. AU - Holmes, David. AU - Rabinstein, Alejandro. AU - Rihal, Charanjit. AU - Gersh, Bernard J.. AU - Lennon, Ryan J.. AU - Bashir, Riyaz. AU - Gulati, Rajiv. PY - 2011/4. Y1 - 2011/4. N2 - Objectives: We sought to determine trends, predictors, in-hospital and long-term outcomes of cerebrovascular events (CVE) related to percutaneous coronary intervention (PCI) over a 16-year period. Background: Despite a temporal increase in patient risk profile and procedural complexity, rates of PCI-related mortality and myocardial infarction have decreased. Temporal trends, characterization, and outcomes after PCI-related CVE in the contemporary era remain unknown. Methods: We performed a retrospective study of 24,126 PCI hospitalizations in 19,165 unique patients, between January 1, 1994, and December 31, 2009, and compared ...

By Michael Crawford, MD, Editor Dr. Crawford reports no financial relationships relevant to this field of study. SYNOPSIS: Nonagenarians can undergo percutaneous coronary interventions with low in-lab complication rates, but 30-day and one-year mortality is considerably higher than in younger patients. SOURCES: Sawant AC, Josey K, Plomondon ME, et al. Temporal trends, complications, and predictors of outcomes among nonagenarians undergoing percutaneous coronary intervention: Insights from the Veterans Affairs Clinical Assessment, Reporting, and Tracking program. JACC Cardiovasc Interv 2017;10:1295-1303. Holmes DR Jr. Four score and 10 . . .

Background Percutaneous coronary intervention (PCI) is a revascularisation intervention for patients with acute coronary syndrome. It is a common procedure, increasingly used over the past decade. Along with PCI, patients are also prescribed a number of medications and adherence to the pharmacological therapies is vital to improved morbidity and mortality. Objective This cross-sectional study sought to evaluate the long term adherence to medications in patients following PCI. Subjects 270 participants who underwent PCI between April 2003 and March 2004 and who met the inclusion criteria were followed up 12-24 months following the PCI. Methods Following obtaining informed consent, a self administered questionnaire was mailed to participants. Information was collected relating to the types of medications taken, medication taking behaviours and storage of medications. Results Overall high rates of self-reported medication adherence were reported. In spite of this, patients continued to miss ...

The goal of the study was to evaluate pretreatment with clopidogrel compared with placebo among the subgroup of patients with ST elevation myocardial infarction (STEMI) treated with thrombolytic therapy who underwent percutaneous coronary intervention (PCI) in the CLARITY-TIMI 28 trial.. ...

Risk stratification is an essential part of appropriately informing patients electing to undergo percutaneous coronary intervention (PCI). This process is also an integral part of the SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery)-pioneered heart team approach in determining the most appropriate revascularisation modality for patients with complex coronary artery disease. The SYNTAX score was pioneered as an anatomical-based risk score to aid in this decision-making process; the lack of clinical variables in this score has, however, been its main limitation. This review examines the important established and evolving contemporary risk models used to aid this risk-stratification process. Risk scores based on clinical and anatomical variables alone and in combination-the latter of which is the subject of continuing research-are all explored. Other areas of discussion include risk scores based on the completeness of revascularisation and emerging concepts such as functional anatomical ...

OBJECTIVE: To derive risk models for percutaneous coronary intervention (PCI) outcomes from clinical and laboratory variables available before the procedure so they can be used for preprocedure risk stratification. PATIENTS AND METHODS: Using the Mayo Clinic registry, we analyzed 9035 PCls on 7640 unique patients from January 1, 2000, through April 30, 2005. We included only the first PCI per patient (n=7457). Logistic regression was used to model the calculated risk score and major procedural complications. Separate risk models were made for mortality and major adverse cardiovascular events (MACE) derived solely from baseline and laboratory characteristics. Final risk scores for procedural death, defined as any death during the index hospitalization, and MACE contained the same 7 variables (age, myocardial infarction ≤24 hours, preprocedural shock, serum creatinine level, left ventricular ejection fraction, congestive heart failure, and peripheral artery disease). RESULTS: Models had ...

This was a phase II trial comparing three doses of intravenous M118 (a novel synthetic anticoagulant with both antithrombin and anti Xa activity) with unfractionated heparin (UFH) in patients undergoing elective percutaneous coronary intervention (PCI).. ...

The study evaluated the in-hospital outcomes of Eptifibatide versus Abciximab in dialysis patients undergoing percutaneous coronary intervention.

Percutaneous coronary intervention (PCI) is associated with a 15% to 35% incidence of periprocedural myocardial injury (PMI). Its spectrum ranges from obvious clinical myocardial infarction to subtle myocardial injury manifested by mild rises in cardiac enzymes. Even in the latter case, the resulting myocardial damage is clinically important, as multiple studies have consistently demonstrated that PMI is associated with increased long-term mortality with a graded risk related to the extent of creatine kinase-MB or cardiac troponin elevation. Despite extensive basic and clinical research and multiple therapeutic approaches, its incidence has not substantially decreased over the last 2 decades. Two patterns of PMI have been recognized by magnetic resonance imaging. Type I is near the intervention site consequent to side branch occlusion, and type II is in the downstream territory of the treated artery where perfusion is compromised mainly due to structural and functional microvascular dysfunction ...

We describe a case of massive coronary thrombus after the coronary stenting due to heparin-induced thrombocytopenia with thrombosis syndrome (HITTS). Only argatroban was able to resolve the thrombus. This is the first case in which argatroban successfully treated massive thrombus during percutaneous coronary intervention in a patient with HITTS.

Introduction: Contemporary risk models for event prediction after percutaneous coronary intervention (PCI) have limited predictive ability. Machine learning (ML) methods have the potential to identify complex non-linear patterns, improving predictive power.. Hypothesis: ML can be used to derive better discriminatory models to identify patients at risk for in-hospital death and congestive heart failure (CHF) rehospitalization after PCI.. Methods: We evaluated 11,709 distinct patients that underwent 14,349 PCIs during 14,024 admissions between 2004-2013 who were prospectively followed in the Mayo Clinic PCI registry. 53 demographic and clinical parameters known at the time of admission and 356 additional parameters available at discharge were examined to identify patients at risk for readmission due to CHF and in-hospital mortality. For each target event, we trained a random forest regression model to estimate the time to event. 8 fold cross-validation was used to estimate model performance. We ...

Thesis, English, Impaction of percutaneous Coronary Intervention (PCI) on Echocardiographic Derived Left Ventricular Parameters and Functions in Patients with Unstable Angina or non st segment Elevation Myocarial Infarction for Hassan Yahya Abu Bkr

Percutaneous coronary intervention (PCI) with stent deployment is the dominant form of myocardial revascularization, with millions of procedures performed worldwide each year.

The advent of aggressive, multidrug antithrombotic therapy during percutaneous coronary intervention (PCI) has led to significant reductions in short- and long-term ischemic outcomes. (See.)However, periprocedural bleeding is a frequent complication

Interventional cardiologists at Northwestern Memorial Hospital have demonstrated outstanding clinical outcomes using an advanced catheter-based procedure called Complete Higher Risk Indicated Percutaneous Coronary Intervention (PCI) or CHIP to open blocked coronary arteries in the high-risk patient.

A select stable population of patients undergoing percutaneous coronary intervention are randomized to standard of care in-hospital stay for one night or early discharge to a nearby hotel. During PCI, patients receive bivalirudin as their anti-coagulant and also must be eligible for an angioseal closure device. Patients that stay overnight in the hotel must be accompanied by a family member. They return to the cath lab the next day for groin check and blood work. Satisfaction questionnaires are filled out by all patients ...

Percutaneous coronary intervention (PCI) aims to restore the supply of blood to the heart by unblocking the narrowed arteries that may be causing your heart failure.

Background-Although numerous studies have reported that cardiac rehabilitation (CR) is associated with reduced mortality after myocardial infarction, less is known about its association with mortality after percutaneous coronary intervention.Methods and Results-We performed a retrospective analysis

OBJECTIVE: To evaluate the short and long-term results of percutaneous coronary interventions (PCI) in patients aged 80 years or older and to identify predictors of event-free survival. METHODS AND RESULTS: Clinical and angiographic data from all pat

Fingerprint Dive into the research topics of Stent loss and retrieval during percutaneous coronary interventions: A systematic review and meta-analysis. Together they form a unique fingerprint. ...

Improvement in left ventricular function following higher-risk percutaneous coronary intervention in patients with ischemic cardiomyopathy.

Discover how Philips percutaneous coronary intervention (PCI) systems and solutions enable you to provide excellent care. Stay current with the latest clinical procedures and technologies.

PLATELET GLYCOPROTEIN-IIB/GLYCOPROTEIN-IIIA INHIBITION WITH INTEGRELIN(TM) DURING PERCUTANEOUS CORONARY INTERVENTION - THE IMPACT-II TRIAL

An oral thrombin receptor antagonist, SCH 530348 has proved safe and effective, and may be better than conventional anti-coagulation treatments for patients receiving percutaneous coronary intervention. Results of the TRA-PCI study were presented at the ACCs New Orleans meeting by David Moliterno who discussed the new data with Peter Goodwin ...

Sigma-Aldrich offers abstracts and full-text articles by [Dan Atar, Håkan Arheden, Alain Berdeaux, Jean-Louis Bonnet, Marcus Carlsson, Peter Clemmensen, Valérie Cuvier, Nicolas Danchin, Jean-Luc Dubois-Randé, Henrik Engblom, David Erlinge, Hüseyin Firat, Sigrun Halvorsen, Henrik Steen Hansen, Wilfried Hauke, Einar Heiberg, Sasha Koul, Alf-Inge Larsen, Philippe Le Corvoisier, Jan Erik Nordrehaug, Franck Paganelli, Rebecca M Pruss, Hélène Rousseau, Sophie Schaller, Giles Sonou, Vegard Tuseth, Julien Veys, Eric Vicaut, Svend Eggert Jensen].

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SHAFFER, ROSE RN, CRNP, BC, CCRN, MSN Cardiology Nurse Practitioner, Thomas Jefferson University Hospital, Philadelphia, Pa. Figure....

Background: Data on racial disparities in major adverse cardiovascular events (MACE) and major hemorrhage (HEM) after percutaneous coronary intervention are limited. Factors contributing to these disparities are unknown. Methods and Results: PRiME-GGAT (Pharmacogenomic Resource to Improve Medication Effectiveness-Genotype-Guided Antiplatelet Therapy) is a prospective cohort. Patients aged ≥18 years undergoing percutaneous coronary intervention were enrolled and followed for up to 1 year. Racial disparities in risk of MACE and HEM were assessed using an incident rate ratio. Sequential cumulative adjustment analyses were performed to identify factors contributing to these disparities. Data from 919 patients were included in the analysis. Compared with white patients, black patients (n=203; 22.1% of the cohort) were younger and were more likely to be female, to be a smoker, and to have higher body mass index, lower socioeconomic status, higher prevalence of diabetes mellitus and moderate to ...

Related Articles 2-Year Clinical Outcomes of an Abluminal Groove-Filled Biodegradable-Polymer Sirolimus-Eluting Stent Compared With a Durable-Polymer Everolimus-Eluting Stent. JACC Cardiovasc Interv. 2019 09 09;12(17):1679-1687 Authors: Xu ...

The principal findings from the present analysis of 8,448 patients with routine measurement of on-treatment PRU using VerifyNow following successful DES implantation are the following: 1) PRU was associated with the occurrence of ST through 2-year follow-up in a monotonically increasing relationship, and in multivariable analyses, PRU within the highest quintile was independently associated with a ,2-fold increase in ST; 2) the lowest PRU quintile was associated with the greatest rate of clinically relevant bleeding in both univariable and multivariable analyses, with similar rates of bleeding at higher PRU levels; and 3) whereas higher PRU was associated with greater all-cause mortality in unadjusted analyses, there was no association between PRU and mortality after multivariable adjustment for baseline differences, with a similar overall hazard for mortality in each PRU quintile.. The finding of high on-treatment PRU has been associated with adverse ischemic outcomes in numerous previous ...

Compared to the transfemoral (TF) route, percutaneous cardiac procedures performed via a transradial (TR) approach are associated with significantly lower morbidity and are more cost-effective....

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TY - JOUR. T1 - Incidence, Predictors, and Outcomes of Acute Ischemic Stroke Following Percutaneous Coronary Intervention. AU - Alkhouli, Mohamad. AU - Alqahtani, Fahad. AU - Tarabishy, Abdulrahman. AU - Sandhu, Gurpreet. AU - Rihal, Charanjit S.. PY - 2019/8/12. Y1 - 2019/8/12. N2 - Objectives: The aim of this study was to assess temporal trends in the incidence of ischemic stroke among patients undergoing percutaneous coronary intervention (PCI), predictors of post-PCI ischemic stroke, and the impact of post-PCI ischemic stroke on in-hospital morbidity, mortality, length of stay, and cost. Background: Data on the incidence and outcomes of ischemic stroke in patients undergoing PCI in the contemporary era are limited. Methods: The National Inpatient Sample was used to identify patients who underwent PCI between January 1, 2003, and December 31, 2016. The incidence of post-PCI ischemic stroke was calculated, and its predictors were assessed. In-hospital outcomes of patients with and those ...

Master thesis, Programme in Medicine TITLE: Predictors of long-term outcome of percutaneous coronary intervention in elderly patients with acute coronary syndrome - a retrospective analysis AUTHOR, YEAR: Maria Lindh, 2012 INSTITUTION, CITY, COUNTRY: Section of Cardiology, Department of Medicine, Sahlgrenska University Hospital/Östra Hospital, Gothenburg, Sweden BACKGROUND: Elderly patients constitute the majority of patients with acute coronary syndrome. Nevertheless, due to a paucity of data, decision-making on the use of percutaneous coronary intervention in this patient group is mainly empirical. Old age is associated with higher risk of adverse outcome of PCI. It is however not well-known what other factors than age that are of prognostic significance. Likely, considering the heterogeneity of the patient group, there is a subgroup of elderly patients for which the prospects of gaining from intervention are greater than for others. By studying and evaluating factors that may be of prognostic

In worldwide, the mortality rate of acute myocardial infarction (AMI) raises year by year. Although the applications of percutaneous coronary intervention (PCI) and anticoagulants effectively reduce the mortality of patients with acute coronary syndrome (ACS), but also increase the incidence of bleeding. Therefore, drugs with stable anticoagulant effects are urgently required. We enrolled 894 patients with acute coronary syndrome who underwent percutaneous coronary intervention in Shenyang Northern Hospital from February 2010 to May 2012; 430 patients were included in the fondaparinux group (2.5 mg/d), and 464 were included in the enoxaparin group (1 mg/kg twice daily). Fondaparinux and enoxaparin were applied for 3-7 days. All patients were treated with tirofiban (10 μg/kg for 3 min initially and 0.15 μg/(kg · min) for 1 to 3 days thereafter). The primary efficacy endpoint was the incidence of a major adverse cerebrovascular or cardiovascular event. The primary safety endpoint was bleeding within 30

In-hospital and late outcome of rescue versus primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction

Background/objectives: Endothelial progenitor cells (EPCs) are circulating mononuclear cells that are released from the bone marrow in response to injury and participate in vascular repair. Some previous studies have suggested an early mobilisation of EPCs following percutaneous coronary intervention (PCI) that could modulate the subsequent risk of restenosis or stent thrombosis. However, those studies did not discriminate between vascular injury caused by PCI and any associated myocardial injury. Myocardial injury alone can influence EPC mobilisation in a non-specific manner, and could therefore confound any association with risk. We investigated the effect of local endothelial trauma following PCI on EPC mobilisation in the absence of myocyte necrosis.. Design: We quantified circulating EPCs from 20 patients immediately before, 6 hours and 24 hours following elective PCI in patients without a 24-hour troponin rise. Absolute counts of EPCs expressing combinations of CD45, CD34, CD133 and kinase ...

Primary percutaneous coronary intervention (PCI) is currently the preferred revascularization strategy in acute trasmural myocardial infarction (AMI). In this setting, about one half of patients will be diagnosed with concomitant multivessel (MV) coronary artery disease, associated with a multitude of negative prognostic factors but also still an independent predictor of adverse cardiac events and increased long-term mortality. Since additional angiographic lesions found at primary PCI are not directly responsile for the acute presentation, their treatment represents a difficult decision-making problem in cardiology. The article summarizes available clinical data on treatment in this setting and also review our current understanding of short-term progression of atherosclerosis after AMI.. ...

Intracoronary epinephrine in the treatment of refractory no-reflow after primary percutaneous coronary intervention: a retrospective study ...

The aim of this study is to evaluate the effect of pre PCI administration of intracoronary nitroprusside on post procedural myonecrosis. Myonecrosis is a prognostically important complication of PCI. Nitric oxide is a potent vasodilator in the resistance arteriolar circulation, and plays a significant role in the control of coronary blood flow through the microcirculation. nitroprussideis a direct donor of nitric oxide. A total of 62 patients were randomized into the NTP (n= 31) or control (n= 31) group. Patients who were scheduled for non-urgent PCI in de novo native coronary arteries were eligible. All patients were pretreated with statin, aspirin and clopidogrel. Myonecrosis was measured by CK-MB elevation 24 h after PCI. The NTP group received intracoronary NTP befor PCI, whereas the control group did not. All patients in NPT group received NTP for prevention of myonecrosis at a dose of at least 50 μg given intrcoronary through guiding catheter. 22 patients received 50μg,7 patients ...

Changes in reimbursement have put pressure on health care facilities to shift more elective percutaneous coronary interventions (PCIs) to

Evidence-based recommendations on prasugrel (Efient) with percutaneous coronary intervention (PCI) for treating acute coronary syndrome (ACS)

Evidence-based recommendations on prasugrel (Efient) with percutaneous coronary intervention (PCI) for treating acute coronary syndrome (ACS)

Percutaneous coronary intervention (PCI) is a non-surgical procedure used to treat narrowing (stenosis) of the coronary arteries of the heart found in coronary artery disease. After accessing the blood stream through the femoral or radial artery, the procedure uses coronary catheterization to visualise the blood vessels on X-ray imaging. After this, an interventional cardiologist can perform a coronary angioplasty, using a balloon catheter in which a deflated balloon is advanced into the obstructed artery and inflated to relieve the narrowing; certain devices such as stents can be deployed to keep the blood vessel open. Various other procedures can also be performed. Primary PCI is the very urgent use of PCI in people with acute myocardial infarction (heart attack), especially where there is evidence of severe heart damage on the electrocardiogram (ST elevation MI). PCI is also used in people after other forms of myocardial infarction or unstable angina where there is a high risk of further ...

TY - JOUR. T1 - Clinical outcomes after percutaneous coronary intervention in non-dialysis patients with acute coronary syndrome and advanced renal dysfunction. AU - N-registry investigators. AU - Uemura, Yusuke. AU - Ishikawa, Shinji. AU - Takemoto, Kenji. AU - Negishi, Yosuke. AU - Tanaka, Akihito. AU - Takagi, Kensuke. AU - Yoshioka, Naoyuki. AU - Umemoto, Norio. AU - Inoue, Yosuke. AU - Morishima, Itsuro. AU - Shibata, Naoki. AU - Asano, Hiroshi. AU - Ishii, Hideki. AU - Watarai, Masato. AU - Murohara, Toyoaki. N1 - Funding Information: H.I. received lecture fees from Astellas Pharma Inc., Astrazeneca Inc., Daiichi-Sankyo Pharma Inc., and MSD K. K. T.M. received lecture fees from Bayel Pharmaceutical Co., Ltd., Daiichi-Sankyo Co., Ltd., Dainippon Sumitomo Pharma Co., Ltd., Kowa Co., Ltd., MSD K. K., Mitsubishi Tanabe Pharma Co., Nippon Boehringer Ingelheim Co., Ltd., Novartis Pharma K. K., Pfizer Japan Inc., Sanofi-aventis K. K., and Takeda Pharmaceutical Co., Ltd. T.M. received unrestricted ...

深入研究「Improvement in door-to-balloon (D2B) time in acute st-elevation myocardial infarction through the D2B alliance - Experience of 15 primary percutaneous coronary intervention centers in Taiwan」主題。共同形成了獨特的指紋。 ...

Purpose of review This paper provides a synopsis of the best evidence to guide bifurcation percutaneous coronary intervention (PCI), with a focus on recent studies. This is with the aim of guiding the...

Background: The changes in serum creatinine level after Percutaneous coronary Intervention has been reported by different authors.. Methods: Total 87 (Male71: Female 16) patients were enrolled in this very preliminary study who underwent elective PCI and has normal serum creatinine level. Total 116 stents were deployed in 108 territories. Mean age for both male : female were (55: 58) yrs. Associated CAD risk factors were Dyslipidemia, High Blood pressure, Diabetes Mellitus, Positive FH for CAD and Smoking (all male).. Results: Among the study group; 65(74.3%) were Dyslipidemic, 74(85%) were hypertensive; 52(58%) patients were Diabetic, FH 12(13.8%), Hypothyroid 3(3.4%) and 30(42.3%) were all male smoker. Female patients were more obese (BMI: M 25: F 28). Average uses of contrast material was 81 ml. Serum Creatinine level was pre-procedural male: female (1.35: 1.44) and post-procedural 2nd day for male: female were (1.24: 1.45). Common stented territory was LAD 48(44.4%), RCA 41(38%), and LCX ...

Background:Coronary artery disease is higher in risk with diabetes mellitus, and diabetesrelateddeaths can lead to ischemic heart disease. We examined the relationship between theglycemic regulation as determined by Hemoglobin A1c and the occurrence of periproceduralcomplications in patients who performed percutaneous coronary intervention (PCI) and hadCoronary artery Bypass Graft (CABG)Objective: To identify associated complications and their sites with Percutaneous CoronaryIntervention in diabetic patientswho performed Coronary Artery Bypass Graft.Methods:The cross-sectional analysis was performed at the cardiology department in ZagazigUniversity Hospital in which all 24 CABG & DM patients were included during the periodbetween January 2019 and January 2020 divided into 12 patients with controlledDM(HbA1c|7)&12 patients with uncontrolled DM (HbA1c|7).Both patients had a completemedical history, a detailed clinical evaluation, and preoperative laboratory work: role of therenal, completion of blood

Background: Remodeling of the radial artery (RA) after transradial percutaneous coronary intervention (TRI) is under studied. Objectives: To examine the impact of TRI on RA diameter and intimal-medial thickness (IMT) in men and women using 55 Mhz ultrahigh frequency duplex ultrasound (UHFDU). Methods: We performed UHFDU at 24 h and 90 days after non-emergent TRI in 41 patients (25 men, 16 women). Changes in RA diameter, IMT and RA injury were compared by patient gender. Multivariate linear regression was used to determine the predictors of RA diameter and IMT.

Percutaneous coronary intervention for ostial lesions of the left main stem in a patient with congenital single left coronary artery: A case report

Percutaneous Coronary Intervention (PCI), also referred to as coronary angioplasty or balloon angioplasty, is a procedure that opens narrowed or blocked blood vessels of the heart.

A percutaneous coronary intervention (PCI) is often called balloon angioplasty. A catheter is inserted into the blood vessels either in the groin (femoral artery) or in the arm (radial artery). Using a special type of X-ray called fluoroscopy; the catheter is threaded through the blood vessels into the heart where the coronary artery is narrowed. […]. ...

Percutaneous coronary intervention (PCI), also known as coronary angioplasty, is a nonsurgical procedure that improves blood flow to your heart.

Elevated CK-MB Levels in Patients after Percutaneous Coronary Intervention is Associated With Increased Two-Year Mortality

Treatments for heart problems:- cardiac pacing, percutaneous coronary intervention, angioplasty, pacemakers, cardioverter defibrillators...

Percutaneous coronary intervention had her humble beginnings in 1977 in Zurich when Dr A Greuntzig, under flouroscopy guidance passed a very high profile and crude catheter ( rubber tubing ) with a balloon at the distal end. Once across the lesion ( which was at the proximal LAD ), he inflated the balloon repeatedly, until the lesion ws flattened and there was no longer any more pressure gradient across the lesion. The patient was a dentist, and the simple balloon angioplasty lasted him about 15 years ...

Ellibs Ebookstore - Ebook: Atlas of FFR-Guided Percutaneous Coronary Interventions - Author: Fineschi, Massimo (#editor) - Price: 230,65€

Cerit L. Angiography-guided percutaneous coronary intervention. Minerva Cardioangiol 2017;65:193. DOI: 10.23736/S0026-4725.16.04254-7 ...

Researchers have led a retrospective single-center study examining simple hemodynamic parameters obtained at the time of cardiac catheterization to predict in-hospital mortality following ST-elevation myocardial infarction ...

The Tp-e/QT ratio was correlated with both short- and long-term outcomes. Analysis of the receiver operating characteristic curve demonstrated that the optimal cutoff value for outcome prediction was a Tp-e/QT ratio of 0.29. Of the 388 patients enrolled, 115 (34.0%) exhibited a Tp-e/QT ratio ≥0.29. Patients with a Tp-e/QT ratio ≥0.29 showed elevated rates of both in-hospital death (21.9% vs 2.3%; P , 0.001) and main adverse cardiac events (MACE) (48.1% vs 15.3%; P , 0.005). After discharge, Tp-e/QT ratios ≥0.29 remained an independent predictor of all-cause death (35.5% vs 5.2%, P , 0.001) and cardiac death (32.3% vs 2.6%, P , 0.001). ...

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