The family Poxviridae is divided in two subfamilies: Entomopoxvirinae, which infect insects, and Chordopoxvirinae, which infect vertebrates[1]. Genera of the subfamily Chordopoxvirinae that may cause human infections include Orthopoxvirus, Parapoxvirus, Molluscipoxvirus and Yatapoxvirus[1, 2]. The genus Orthopoxvirus (OPXV) is the most relevant in terms of human public health concerns and includes viruses that have been associated with severe febrile, rash illness in humans. Its members include: Variola virus, a solely human pathogen and the etiological agent of smallpox[2-4]; Monkeypox virus, a zoonotic disease that causes a generalized rash similar to smallpox with up to 10% case fatality rate[5]; Vaccinia virus (VACV), the smallpox vaccine which can produce generalized illness in immunocompromised individuals[6]; and Cowpox virus, another zoonotic disease which can cause generalized illness in immunocompromised individuals[6, 7]. In immunocompetent individuals, infection with vaccinia or ...
Via Scoop.it - Virology NewsInvestments in the development of new drugs for orthopoxvirus infections have fostered new avenues of research, provided an improved understanding of orthopoxvirus biology and yielded new therapies that are currently progressing through clinical trials. These broad-based efforts have also resulted in the identification of new inhibitors of orthopoxvirus replication that target…
Vaccine-Induced Protection against Orthopoxvirus Infection Is Mediated through the Combined Functions of CD4 T Cell-Dependent Antibody and CD8 T Cell Responses
camelpox DNA extraction - posted in Molecular Biology: Dear All, i have been struggling in trying to extract this virus ... tried different treatment ways; boiling, sonication ... without any fruitful results ( am using a positive control sample here ; positive by CPE ) does any of you ever worked with it ??? would be more than grateful if anyone can help in this ... thanx in advacnce, nightingale
However, since this time the SEC has delegated its role in developing and presenting accounting and financial reporting standards to the private sector. In 1973, the Financial Accounting Standards Board (FASB), a not-for-profit organization whose primary purpose is to develop generally accepted financial reporting standards (GAAP) for U.S. issuers. The SEC has currently delegated authority to the FASB to be the sole provider of authoritative U.S. GAAP (however, the SECs own Rules and Interpretive Releases are also authoritative GAAP for companies who file with the SEC). In recent years there has been some discussion by the SEC about the role that International Financial Reporting Standards (IFRS) should play in U.S. GAAP. If the SEC choses to allow U.S. issuers to file financial statements using IFRS, the role of U.S. GAAP, and thus the role of the FASB would be limited ...
In addition, the Company is continuing with its strategic alternatives review process. Sigma Designs does not plan to hold a conference call in association with the information in this news release. The Company will provide an update on these actions when it determines that further disclosures are appropriate. Use of Non-GAAP Financial Information In addition to reporting financial results in accordance with generally accepted accounting principles ("GAAP"), Sigma reports non-GAAP financial measures, as Sigma believes that evaluating its ongoing operating results may be difficult if limited to reviewing only GAAP financial measures. Non-GAAP financial measures are not a substitute for financial information prepared in accordance with GAAP. Therefore, non-GAAP financial measures should not be considered in isolation, but should be considered together with the most directly comparable GAAP financial measures and the reconciliation of the non-GAAP financial measures to the most directly comparable ...
Health,...SCHAFFHAUSEN Switzerland Nov. 10 /- ... ($ millions except per-share amounts) ...Tyco International Ltd. (NYSE: a hrefhttp://studio-5.financialconte...For the full year revenue of $17.2 billion declined 15%. Organic rev...,Tyco,International,Reports,Fourth,Quarter,Earnings,From,Continuing,Operations,Before,Special,Items,of,$0.61,Per,Share,and,GAAP,Earnings,of,$0.44,Per,Share,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Health,... Reaffirms 2008 GAAP EPS Guidance Reflecting Growth of 27-29 Percent ... 2007 ... First-Quarter Year-Over-Year Highlights (adjusted for January 2008 ...,Medco,Reports,Strong,First-Quarter,Results;,Record,EPS,,Mail-Order,Volume,,Generic,Dispensing,Rates,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Adjusted Financial Measures The Company reports adjusted net income and adjusted net income per diluted share, in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. The Companys financial measures under GAAP include stock-based compensation expense, amortization of debt-related costs, amortization related to acquisitions, changes in contingent liabilities, net losses of Viking Therapeutics, mark-to-market adjustment for amounts owed to licensors, fair value adjustments to Viking Therapeutics convertible note receivable and warrants, unissued shares relating to the Senior Convertible Note and others that are listed in the itemized reconciliations between GAAP and adjusted financial measures included in this press release. However, other than with respect to total revenue, the Company only provides guidance on an adjusted basis and does not provide reconciliations of such forward-looking adjusted measures to GAAP due to the inherent ...
All numbers in the table above are GAAP except where expressly referenced as non-GAAP. The Company does not provide GAAP income per common share on a forward-looking basis because the Company is unable to predict with reasonable certainty business development and acquisition-related expenses, purchase accounting fair value adjustments, and any unusual gains and losses without unreasonable effort. These items are uncertain, depend on various factors, and could be material to results computed in accordance with GAAP. The Companys financial guidance for 2017 is subject to the risks identified below. Non-GAAP Financial Measures This press release contains non-GAAP financial measures. Investors should consider this non-GAAP information in addition to, and not as a substitute for, financial measures prepared in accordance with U.S. GAAP. In addition, this non-GAAP financial information may not be the same as similar measures presented by other companies. The Companys non-GAAP revenues include (as ...
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Condensed Consolidated Statements of Income and Reconciliation of GAAP Earnings to "Adjusted" Earnings (In millions, except per share data) (Unaudited) Three Months Ended Three Months Ended September 30, 2009 September 30, 2008 ------------------ --------------------- Adjust- Adjust- GAAP ments "Adjusted" GAAP (a) ments "Adjusted" ---- ------- -------- -------- ------- -------- Revenues: Product sales $3,736 $- $3,736 $3,784 $- $3,784 Other revenues 76 - 76 91 - 91 --- --- --- --- --- --- Total revenues 3,812 - 3,812 3,875 - 3,875 ----- --- ----- ----- --- ----- Cost of sales (excludes amortization of certain acquired intangible assets presented below) 545 (3) (b) 542 677 (3) (b) 590 (84) (h) Research and development 647 (13) (b) 613 729 (12) (b) 700 (3) (c) (17) (d) (18) (d) Selling, general and adminis- trative 932 (13) (b) 913 900 (10) (b) 890 (6) (c) Amortization of certain acquired intangible assets 74 (74) (e) - 74 (74) (e) - Other charges 9 (1) (c) - 12 (8) (c) - (8) (f) (4) (f) --- --- ...
To supplement our consolidated financial statements, which statements are prepared and presented in accordance with GAAP, we use the following non-GAAP financial measures: non-GAAP operating income, non-GAAP operating margin, non-GAAP net income, non-GAAP EPS, and free cash flow. The presentation of this financial information is not intended to be considered in isolation or as a substitute for, or superior to, the financial information prepared and presented in accordance with GAAP. For more information on these non-GAAP financial measures, please see the tables captioned Reconciliations of non-GAAP results of operations measures to the nearest comparable GAAP measures and Reconciliation from net cash provided by operating activities to free cash flow included at the end of this release.. We use these non-GAAP financial measures for financial and operational decision making and as a means to evaluate period-to-period comparisons. Our management believes that these non-GAAP financial measures ...
The International Accounting Standards Board (IASB) and the US Financial Accounting Standards Board (FASB) today published for public comment a discussion paper setting out a joint approach for the recognition of revenue.. Revenue is an important number to users of financial statements in assessing a companys performance and prospects. However, revenue recognition requirements in US generally accepted accounting principles (GAAP) differ from those in International Financial Reporting Standards (IFRSs) and both are considered in need of improvement. The requirements in US GAAP comprise numerous standards-many are industry-specific and some can produce conflicting results for economically similar transactions. Although IFRSs contain fewer standards on revenue recognition, its two main standards have different principles and can be difficult to understand and apply beyond simple transactions.. The boards objective is to improve the existing guidance in both IFRSs and US GAAP by developing a ...
Tuesday, October 25, 2016 7:00:04 AM ET --Third Quarter GAAP Earnings per Share of $0.23; Adjusted Earnings per Share of $0.56 increased 37 percent Baxter International Inc. (BAX ) today reported results for the third quarter of 2016, and increased its earnings per share outlook for full-year 2016. Baxter s third quarter worldwide sales totaled $2.6 billion, an increase of 3 percent on a reported basis and 4 percent on a constant currency basis as compared to the prior-year period. We are pleased with the continued strength across our core franchises as well as our improved financial performance, both of which are reflected in our third quarter results, said Jose (Joe) E. Almeida. Given this progress, we are intensifying our focus on portfolio management and innovation to accelerate our efforts to introduce new products and therapies. Financial Results During the quarter, Baxter reported income from continuing operations of $127 million, or $0.23 per diluted share, on a GAAP (Generally Accepted ...
NPH serves approximately 3,200 advisors and $120 billion of client assets Estimated run-rate GAAP EPS accretion of $0.25- 0.40 by the end of 2018; $0.40- 0.55 prior to amortization of intangible assets* Estimated run-rate EBITDA* accretion of $75- 100 M by the end of 2018 Transaction simultaneously signed and closed on August 15 th, 2017 Conference call with...
Double-Digit Non-GAAP EPS Growth in Third Quarter 2011 Non-GAAP EPS of 0.94 GAAP EPS of 0.55 Worldwide Sales Growth of 8 Percent, Including 5 Percent From Forei
1. Which of the following is not a characteristic of Managerial Accounting? a. Emphasis on individual projects within the organization. b. Doesnt conform to GAAP c. Uses projections and estimates as well as historical.
Cow Pox viral disease of dairy animals It is caused by Orthopox virus having a place with family Poxviridae. Orhtopox infections are comparable.
Smallpox, the only human infectious disease to have been eradicated, remains a threat as a potential agent of bioterrorism. Mortality rates during natural outbreaks of smallpox varied widely, a feature partially attributed to strain-specific virulence of the etiological agent, the orthopoxvirus variola virus (VARV) [1]. An understanding of the genetic determinants of virulence of VARV is critical for predicting the potential of different strains for causing severe epidemics.. We analyzed the genome-wide single nucleotide polymorphisms (SNPs) of a collection of 35 temporally, geographically and epidemiologically diverse VARV isolates housed at the US Centers for Disease Control and Preventions secure repository (previously described in [2]) for associations with VARV virulence. We investigated the only known metric of innate virulence of these isolates, their case fatality rates (CFRs), which range from ,1-30% [2]. Previously, outbreaks of smallpox have been classified as major when they ...
One of the great success stories of modern medicine is the eradication of smallpox virus that was declared in 1980 after a long vaccination campaign with vaccinia virus. A risk remains today of the resurgence of smallpox virus from a frozen source such as the melting of permafrost [1]. Another risk is the spread of an orthopoxvirus from an animal reservoir to the human population. The present work focuses on vaccinia virus, which is a safe model system to study poxviruses. The high-resolution structure that has been obtained of components of the vaccinia virus DNA replication machinery will facilitate the development of drugs and help to understand orthopoxvirus drug resistance.. The crystal structure determination of vaccinia virus polymerase was challenging due to the radiation sensitivity of the long needle-like DNA polymerase crystals obtained from low amounts of protein produced in insect cells. The use of the helical scan capability at the ESRF with a simultaneous rotation and translation ...
The poxvirus infection is caused by a DNA virus from the Poxviridae virus family, specifically from the Orthopoxvirus genus. This is a relatively common transmitted virus, but it can be readily inactivated by several types of viral disinfectants.
GaaP: PSF- and aperture-matched photometry using shapelets: We describe a new technique for measuring accurate galaxy colours from images taken under different
SAN RAFAEL, Calif., Oct. 27, 2016 (GLOBE NEWSWIRE) -- BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) today announced financial results for the third quarter ended September 30, 2016. GAAP net loss was $43 million, or $(0.26) per basic and diluted share, for the third quarter of 2016, compared to GAAP net loss of $91 million, or $(0.57) and $(0.60) per basic and diluted share, respectively, for the third quarter of 2015. Non-GAAP income was $3 million for the quarter ended September 30, 2016, compared to non-GAAP loss of $41 million for the third quarter of 2015.. The change in GAAP net loss and non-GAAP income and loss compared to the prior year quarter was primarily due to increased gross margins from Naglazyme, Kuvan and Vimizim net product revenues, partially offset by increased selling, general and administrative expenses for Vimizim and Kuvan.. Total BioMarin Revenues were $280 million for the third quarter of 2016, an increase of 34% compared to the same period in 2015. Vimizim net product ...
Background Next-generation sequencing (NGS) technologies have greatly promoted the genomic study of prokaryotes. However, highly fragmented assemblies due to short reads from NGS are still a limiting...
In this press release, Vertexs financial results and financial guidance are provided in accordance with accounting principles generally accepted in the United States (GAAP) and using certain non-GAAP financial measures. In particular, non-GAAP financial results and guidance exclude (i) stock-based compensation expense, (ii) revenues and expenses related to business development transactions including collaboration agreements and asset acquisitions, (iii) revenues and expenses related to consolidated variable interest entities, including asset impairment charges and related income tax benefits and the effects of the deconsolidation of a variable interest entity and (iv) other adjustments. These results are provided as a complement to results provided in accordance with GAAP because management believes these non-GAAP financial measures help indicate underlying trends in the companys business, are important in comparing current results with prior period results and provide additional information ...
Citigroup notes that following through on their call into what they thought would be the last good Q before big risk develops, they are downgrading SPWRA from Hold to Sell taking advantage of ~25% move post-earnings. The Street is already negative on this sector (firm highlighted 09 supply shock back in May 08), but this is a 100% stock-specific call. The bottom line here is that they think a big miss is coming in CQ1 as classic signs of inventory risk are developing in its components biz, while CQ4 should represent a multi-year peak in its margin structure. With respect to liquidity, it has access to cheap money through a term-loan but will continue to skate on thin ice as it looks unlikely to generate FCF through C2010. Risks to the call include potential for SPWRA to self-finance projects very near-term, which could mute some channel risk (albeit w/other ramifications). F09 (GAAP) from $2.29 to $1.92, F10 from $3.06 to $2.60. Target $55 to $30 on lower multiple on GAAP EPS ...
Citigroup notes that following through on their call into what they thought would be the last good Q before big risk develops, they are downgrading SPWRA from Hold to Sell taking advantage of ~25% move post-earnings. The Street is already negative on this sector (firm highlighted 09 supply shock back in May 08), but this is a 100% stock-specific call. The bottom line here is that they think a big miss is coming in CQ1 as classic signs of inventory risk are developing in its components biz, while CQ4 should represent a multi-year peak in its margin structure. With respect to liquidity, it has access to cheap money through a term-loan but will continue to skate on thin ice as it looks unlikely to generate FCF through C2010. Risks to the call include potential for SPWRA to self-finance projects very near-term, which could mute some channel risk (albeit w/other ramifications). F09 (GAAP) from $2.29 to $1.92, F10 from $3.06 to $2.60. Target $55 to $30 on lower multiple on GAAP EPS ...
(Income and EPS amounts are attributable to Tyco common shareholders) ($ millions, except per-share amounts) Tyco International Ltd.
Money matters can be intimidating for even the smartest people. However, having a solid understanding of basic financial terms and methods is crucial to your career. When terms like ROI, EBIT, GAAP, and extrapolation join the conversation, youll want to know what people are talking about, and youll want to be able to
Listed companies within the EU are obligated to report in accordance with the international standard IFRS since 2005. This means that listed companies as main principle, can choose fair value when reporting investment properties according to IAS 40. This standard does not give clear guidance of how fair value should be calculated and previous research argues that this has contributed to difficulties when comparing financial reports. This has affected the comparability of European real estate companies, as the absence of a general valuation standard has impelled companies to address national GAAP for guidance. There has been a demand for further guidance, which has resulted in the development of IFRS 13 Fair value measurement. The purpose of IFRS 13 is to clarify and define the meaning of fair value and how the valuation should be carried out. Despite common international standards, financial reporting in different countries is based on certain values and traditions that may affect accounting ...
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Quarterly Revenues Increased 5 Percent Compared with the Prior-Year Quarter Q3 GAAP Operating Income of $34 Million, Including $4.6 Million Bad Debt Expense and an Anticipated Asset Sale Gain of $3.8 Million Q3 Operating Income Excluding the Bad Debt Expense was $39 Million, Exceeding Harscos Guidance Range Due Mainly to Strong Performance in Metals&...
Test code: S0229 - Ultrasensitive qualitative detection of camelpox virus by real time PCR. Camelpox virus (CMLV) belongs to the family poxviridae, subfamily chordopoxvirinae, genus Orthopoxvirus. This DNA virus infects both old world camelids (eg dromedaries and Bactrian camels) and new world camelids (eg llamas and alpacas). The virus was first reported in Russia and later in India. The disease occurs throughout camel breeding areas of Northern Africa, the Middle East, and Asia, but has not been reported in wild camels in Australia.. Infected animals can develop fever, local or generalized pox lesions on the skin and in the mucous membranes of the mouth and respiratory tract. Lesions follow the usual pattern of pox lesions, tending to be most concentrated around the face, including eyelids, nostrils, and margins of the pinnae. In severe cases, the whole head may be swollen and intense pruritus may be seen. Later, skin lesions may extend to the neck, limbs, genitalia, mammary glands, and ...
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine kinase gene amplicon sequences (339 bp) from 21 lynx were all identical to those from cowpox virus isolated from a person in Norway and phylogenetically closer to monkeypox virus than to vaccinia virus and isolates from 2 persons with cowpox virus in Sweden. Prevalence was higher among animals from regions with dense, rather than rural, human populations. Lynx are probably exposed to OPV through predation on small mammal reservoir species. We conclude that OPV is widely distributed in Sweden and may represent a threat to humans. Further studies are needed to verify whether this lynx OPV is cowpox virus.
Cowpox is an zoonotic viral disease from the Poxiviridae family and stems from the Orthopoxvirus genus. It causes postular lesions on teats and udders of female cows. Cowpox is transmitted to humans who may milk the infected cow. Cowpox is related to the variola virus (smallpox) which is exclusive to humans with a mortality rate of 40 % when infected [5]. The pathogen is easily transferred in areas of high population, poverty , poor malnutrition and sanitation which create favorable conditions, as with any other virus. Smallpox was one of the first vaccines made and was generated through cowpox[8]. During the 16th century Edward Jenner investigated claims that farmers or milkmaids that came in contact with cowpox did not develop smallpox. He used the cowpox virus to create his own vaccine. After much rejection, his research and theory were accepted[6]. Today the World Health Organization is heavily dedicated to continue eradicating smallpox. This year alone it cost 1 billion to save lives of ...
Definition of variola virus in the Definitions.net dictionary. Meaning of variola virus. What does variola virus mean? Information and translations of variola virus in the most comprehensive dictionary definitions resource on the web.
protein common to the parapoxvirus, orthopoxvirus, leporipoxvirus and avipoxvirus genera has been identified, prepared by alkaline extraction of the virion. Subsequent investigations have shown four cross-reacting polypeptides between orthopoxviruses and leporipoxviruses, and one between capri-poxviruses and parapoxviruses. However, none of these are significant in cross-immunity between the genera.. Within the orthopoxviruses, there is good cross-immunity between all the members, exemplified by the use of vaccinia to protect against smallpox (variola). The antigens which stimulate protective antibodies are present in the surface tubular elements and in the envelope derived from modified cellular membrane that surrounds the naturally released virion. Virions released from disrupted cells lack this external membrane and are reported to be less infectious. The envelope also contains the glycoprotein hemagglutinin, which is common to all orthopoxviruses but absent from the other seven genera. ...
Exports of Calcium Phosphate CMLV in Russia decreased to 28.90 USD Million in January from 382.22 USD Million in December of 2016. Exports of Calcium Phosphate CMLV in Russia averaged 135.63 USD Million from 1994 until 2017, reaching an all time high of 622.70 USD Million in December of 2008 and a record low of 5.90 USD Million in January of 1994. Russia accounts for Exports of Calcium Phosphate using cumulative values for each year (CMLV). This page includes a chart with historical data for Russia Exports of Calcium Phosphate CMLV.
Generally accepted accounting principles (GAAP) currently require that state and local governments present as part of their basic audited financial statements a budget to actual comparison statement for governmental funds with annual appropriated budgets. GAAP require that this budgetary comparison statement be presented on the budgetary basis of accounting to demonstrate legal compliance. If the budgetary basis of accounting differs from GAAP, as is often the case, GAAP further require that a reconciliation between the two bases of accounting be presented. This treatment has provided an invaluable link between the legal budget and GAAP financial reporting, which has served to enhance the credibility of both.. Recently, the Governmental Accounting Standards Board (GASB) has explored the possibility of removing the budgetary comparison statement from the basic audited financial statements, mandating instead that it be presented as "required supplementary information" (RSI). By definition, RSI ...
Vaccinia virus (VV) is a large DNA virus belonging to the Orthopoxvirus family. The viral replicative life cycle takes place solely within the cytoplasm of a mammalian host cell. The VV genome contains 196 open reading frames which are expressed in a highly regulated and temporal fashion in order to bring about the production of a mature virion. In the process of viral replication many VV proteins are synthesized that require posttranslational modifications to become functional. A few of these modifications include, glycosylation, ADP-ribosylation, phosphorylation, fatty acid acylation, and proteolytic processing. This last modification is especially important with regard to the structural proteins of the virus in that they undergo prysis for an infectious virus particle to be formed, a common theme in viral systems. In order to understand these events in more detail, three abundant virion protein constituents 4a, 4b, and 25K were chosen as models for study. The three main questions we wanted to ...
management, the company also believes that these non-GAAP financial measures are useful to investors and analysts since these measures allow for greater transparency with respect to key financial metrics the company uses in assessing its own operating performance and making operating decisions. These non-GAAP financial measures are not meant to be considered in isolation or as a substitute for comparable GAAP measures; should be read in conjunction with the companys condensed consolidated financial statements prepared in accordance with GAAP; have no standardized meaning prescribed by GAAP; and are not prepared under any comprehensive set of accounting rules or principles. In addition, from time to time in the future there may be other items that the company may exclude for purposes of its non-GAAP financial measures; and the company has ceased, and may in the future cease, to exclude items that it has historically excluded for purposes of its non-GAAP financial measures. Likewise, the company ...
The CDC has announced that a new orthopoxvirus has been discovered in two men from the nation of Georgia in western Asia. Though both men survived the disease, disease experts arent taking any chances.
Non-GAAP Financial Measures The adjusted non-GAAP (U.S. Generally Accepted Accounting Principles) financial measures discussed above and in the tables below for the three months ended March 31, 2014 and 2013 exclude changes in contingent liabilities, mark-to-market adjustment for amounts owed to licensors, and stock-based compensation expense. Management has presented net income, net income per share, income from continuing operations and income from continuing operations per share in accordance with GAAP and on an adjusted basis. Ligand believes that the presentation of non-GAAP financial measures provides useful supplementary information to and facilitates additional analysis by investors. Ligand uses these non-GAAP financial measures in connection with its own budgeting and financial planning. These non-GAAP financial measures are in addition to, and not a substitute for, or superior to, measures of financial performance prepared in conformity with GAAP. Conference Call Ligand management will ...
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p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Fortunately, in April 1977, India was declared a small pox free country. Small pox was once a major killer throughout the world and its eradication has prevented two million deaths, a few hundred cases of blindness and 10-15 million cases of diseases. Causative Agent Small pox is an infectious disease caused by the variola virus…. [ Continue Reading → ]. ...
into;. * Providers offering outsourced XBRL tagging services;. * Providers offering XBRL consulting and other specialist support services. Source: ICAEW and KPMG.. What does HMRC want?. The pack containing Corporation Tax online submissions will need to comprise: * Corporate Tax Return forms (Forms CT600) in XML. * Corporation Tax computation in iXBRL. * Legal entity accounts (UK GAAP or IFRS) in iXBRL. * Other supporting schedules in PDF. Source: ICAEW and KPMG.. ...
Gilead Sciences, Inc. (Nasdaq: GILD) announced today its results of operations for the second quarter ended June 30, 2004. Total revenues for the second quarter were $319.7 million, up 34 percent, compared to total revenues of $238.9 million for the second quarter of 2003. Operating cash flow for the quarter increased by 106 percent to $122.5 million, compared to $59.4 million for the same period last year.. Net income for the second quarter 2004 was $111.5 million, or $0.49 per diluted share, an increase of 11 percent compared to net income of $100.4 million, or $0.46 per diluted share, for the second quarter of 2003. Included in the second quarter 2004 net income is an after-tax gain of $1.6 million resulting from the liquidation of Gileads equity position in EyeTech Pharmaceuticals, Inc. Pre-tax income increased 53 percent from $105.6 million to $161.5 million. The difference between the growth rates is principally due to the companys effective GAAP tax rate, which increased to 31 percent ...
Asset Management reviews, analyzes and evaluates the audited financial statements, which are required to be filed by project owners and submitted in accordance with Generally Accepted Accounting Practice (GAAP) and to insure that project operations are in