The serum protein 1-acid glycoprotein (AGP), also known as orosomucoid, is normally referred to as an archetypical positive acute phase protein. as analyzed by 2-D electrophoresis. This MAb was utilized to build up an immunoassay (ELISA) for quantification of AGP in pig serum samples. The adult serum concentrations of pig AGP had been in the number of 1C3 mg/ml in several regular pig breeds although it was low in G?ttingen and Ossabaw minipigs (in the 0.3 to 0.6 mg/ml vary) and higher in young (2C5 times old) regular pigs (mean: 6.6 mg/ml). Amazingly, pig AGP was discovered to Betanin work as a poor acute phase proteins during a selection of experimental infections and aseptic irritation with significant decreases in serum focus and in hepatic ORM1 expression through the acute stage response. To your understanding this is actually the first explanation in virtually any species of AGP being truly a negative severe phase protein. Launch Alpha-1-acid glycoprotein (AGP), also referred to as ...
Three-week dosing periods at one of six oral phenobarbital doses between 15 and 400 mg/day were used to achieve steady states for induction of plasma alpha 1-acid glycoprotein concentration (AGP) in beagle dogs. In this way, the characteristics of the dose-response relationship between phenobarbital concentration and the extent of induction could be evaluated. With the 400 mg/day dose of phenobarbital, AGP increased nearly 13-fold. The response of AGP was found to depend on the square of the phenobarbital concentration. Analysis of the decay of AGP when phenobarbital dosing was discontinued showed a kinetic pattern governed by multiple rate processes. This was the result of persistence of the phenobarbital, the turnover of some metabolic precursor to AGP, and the turnover of AGP itself. ...
The investigators found that gallbladder motility was stronger in pancreatitis patients than in patients with uncomplicated symptomatic gallstones.. Smaller and more gallstones were detected in patients with pancreatitis than patients with symptomatic gallstones.. In addition, the team noted that crystallization occurred much faster in the bile of pancreatitis patients, possibly because of higher mucin concentrations.. The researchers found no significant differences in types of gallstones, relative biliary lipid contents and cholesterol saturation indexes.. The team also observed no significant differences in bile salt species composition, phospholipid classes, total protein or immunoglobulin (G, M, and A), haptoglobin, and alpha-1 acid glycoprotein concentrations.. Dr Venneman s team concluded, Patients with small gallbladder stones and/or preserved gallbladder motility are at increased risk of pancreatitis. The potential benefit of prophylactic cholecystectomy in this patient category has yet ...
Definition : Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids (typically serum) to determine the protein alpha-1-acid glycoprotein (AAG), also known as orosomucoid. AAG is a plasma protein whose concentration rises significantly during acute inflammatory processes (i.e., it is an acute-phase reactant). Some causes of acute inflammatory responses include surgery, myocardial infarction, infections, and/or tumors. Increased levels of AAG typically occur within 12 hours of the injury and decrease in 4 or 5 days.. Entry Terms : "Orosomucoid Determination Reagents" , "Alpha-1-Acid Glycoprotein (AAG) Determination Reagents" , "AAG (Alpha-1-Acid Glycoprotein) Determination Reagents" , "Reagents, Alpha-1-Acid Glycoprotein" , "Reagents, Immunoassay, Protein, Alpha-1-Acid Glycoprotein". UMDC code : 17256 ...
Orosomucoid (ORM) or alpha-1-acid glycoprotein (α1AGp,[1] AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein).[2] Plasma levels are affected by pregnancy, burns, certain drugs, and certain diseases, particularly HIV.[2] The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic (positively charged) drugs (whereas albumin carries acidic (negatively charged) and neutral drugs), steroids, and protease inhibitors.[2][3] Aging causes a small decrease in plasma albumin levels; if anything, there is a small increase in alpha-1-acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal.[4] AGP shows a complex interaction with thyroid ...
LAB780Hu71, Biotin-Linked Polyclonal Antibody to Orosomucoid 2 (ORM2), AGP-B; AGP2; Alpha-1-Acid Glycoprotein Type 2 | Products for research use only!
PAB780Hu01, Polyclonal Antibody to Orosomucoid 2 (ORM2), AGP-B; AGP2; Alpha-1-Acid Glycoprotein Type 2 | Products for research use only!
Serum alpha-1-acid glycoprotein (AGP) concentration and its microheterogeneity were measured in 46 patients with major depressive disorder and in 20 age- and sex-matched controls. The changes in major...
TY - JOUR. T1 - Receptor-mediated uptake of human α1-acid glycoprotein into liver parenchymal cells in mice. AU - Matsumoto, Kazuaki. AU - Nishi, Koji. AU - Kikuchi, Mari. AU - Watanabe, Hiroshi. AU - Nakajou, Keisuke. AU - Komori, Hisakazu. AU - Kadowaki, Daisuke. AU - Suenaga, Ayaka. AU - Maruyama, Toru. AU - Otagiri, Masaki. PY - 2010/1/1. Y1 - 2010/1/1. N2 - Human α1-acid glycoprotein (AGP), a serum glycoprotein, is thought to have anti-inflammatory effects by a mechanism that is not well understood. In this study, we investigated the pharmacokinetics of AGP in mice using enzymatically modified AGP (AGP with the sialic acids removed, asialo-AGP, and with both sialic acids and galactose removed, agalacto-AGP). It was observed that AGP was eliminated from the circulation slowly, and was mainly taken up by the liver. The elimination of labeled AGP, asialo-AGP and agalacto-AGP from the circulation was suppressed in the presence of excess unlabeled AGP, asialo-AGP and agalacto-AGP, ...
Alpha1?acid glycoprotein (AGP) is a highly glycosylated lipid?binding acute?phaseprotein. Although the exact mechanisms are unknown, several studies havesuggested that AGP may regulate the function of neutrophils and hence modulateinflammatory responses. The general aim of this thesis was to investigate if AGP isable to mediate intracellular signalling in neutrophils through binding to specificreceptors.Measurements of intracellular calcium concentration showed that AGP elicited asmall rise in [Ca2+]i in neutrophils that was markedly enhanced by pre?treatmentwith anti?L?selectin antibodies. In contrast, desialylation of AGP reduced the Ca2+mobilizing capacity significantly. The AGP?induced Ca2+ signal was mediatedthrough Src tyrosine kinases, PLC and PI3K which suggests involvement of cellsurface receptors. Indeed, AGP was shown to bind to, and mediate Ca2+ signallingthrough, sialic acid binding immunoglobulin?like lectin (Siglec)?5 and/or ?14.Increased fucosylation of AGP is common during ...
Objectives: We aimed to investigate serum levels of S100B, S100A1, and Zinc-α2- glycoprotein (ZAG) in men and women and to find association of these proteins with anthropometric, metabolic and clinical indices. Methods: Eighty-eight apparently healthy adults, 43 men and 45 women, participated in the study. The participants body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressure (SBP and DBP) were measured. Serum levels of total cholesterol (TC), triglyceride (TG), low and high density lipoprotein cholesterol (LDL-C and HDL-C), fasting blood sugar (FBS), insulin, S100B, S100A1 and ZAG protein were examined by enzymatic and ELISA laboratory methods. Homeostatic model assessment- insulin resistance (HOMA-IR) index was calculated. Results: Serum levels of S100B, S100A1 and ZAG were comparable between men and women groups. S100B protein was positively associated with TG (r= 0.41, p= 0.006), SBP (r= 0.46, p= 0.002), and DBP (r= 0.37, p= 0.02), but negatively with HDL-c ...
Gentaur molecular products has all kinds of products like :search , ICL \ Dog Alpha 1_Acid Glycoprotein \ E-40AGP for more molecular products just contact us
Liver slices from normal rats and those suffering from inflammation for 24-48 h were incubated with L-[-14C]leucine or D-[-14C]glucosamine. Immunological techinques coupled with radioautography indicated that the microsome fraction prepared from slices contained the subcellular site of synthesis of the polypeptide chain of serum albumin, and the polypeptide and carbohydrate chains of alpha-1-acid glycoprotein; both proteins were also present in the medium in labelled forms. The contents of albumin and alpha-1-acid glycoprotein in the medium and in extracts of liver from experiments with liver slices from control rats and 8-72 h experimental rats were determined using the quantitative precititin technique. There was a net increase in synthesis of both proteins when slices from control and experimental animals were used, the increase showing up in medium protein. However, slices from livers from 8-72 h experimental rats had a greater capacity for synthesis of alpha-1-acid glycoprotein and lower capacity
Diabetes Res Clin Pract. 2010 Jul;89(1):16-21. Epub 2010 Apr 14. Christiansen MS, Hesse D, Ekbom P, Hesse U, Damm P, Hommel E, Feldt-Rasmussen B, Mathiesen E. Source Department of Clinical Biochemistry and Department of Medicine, Amager Hospital, Italiensvej 1, Copenhagen S, Denmark. [email protected] Abstract AIMS: We evaluated the urinary orosomucoid excretion (UOE) as a biomarker of preeclampsia and preterm delivery in pregnant women with type 1 diabetes. METHODS: Singleton pregnant women with pregestational type 1 diabetes were included provided one urine sample had been collected before 17 gestational weeks. Serum and urinary orosomucoid were analysed by immunoturbidimetry. Primary outcome measurements were development of preeclampsia (blood pressure,140/90mmHg and proteinuria) and preterm delivery before 37 weeks. RESULTS: In total 173 women were included. The UOE increased during pregnancy. Preeclampsia developed in 20 women and 65 women delivered preterm. Using logistic regression ...
I had been working with a different peptide company for custom peptides…but ran into a spate of problems - lost orders, huge delays, and bad technical help. So we switched to NEP. After that, everything has gone swimmingly. Pricing, honestly, is a bit more than I was paying before, but as with many other things in life, you get what you pay for ...
Reject due to: Room temperature samples received at Quest are unacceptable.. Spin: Y. Aliquot: Y. Temp: 2 - 4 C. Storage location: Refrigerate sample in the CPA refrigerator send-outs rack. Avoid freezing and thawing.. Off-site collection: Spin sample and aliquot into plastic tube. Transport refrigerated.. ...
F. Zsila, Fitos, I., Bencze, G., Keri, G., and Orfi, L., "Determination of human serum α1-acid glycoprotein and albumin binding of various marketed and preclinical kinase inhibitors", Current Medicinal Chemistry, vol. 16, no. 16, pp. 1964 - 1977, 2009. ...
I. Fitos, Simon, Á., Zsila, F., Mády, G., Bencsura, Á., Varga, Z., Orfi, L., Kéri, G., and Visy, J., "Characterization of binding mode of imatinib to human α1-acid glycoprotein.", Int J Biol Macromol, vol. 50, no. 3, pp. 788-95, 2012. ...
Returns the values of the row inserted as a hash reference, with the attribute names as keys. These values are provided as-is, so they may include objects passed to ...
article{6a3b745a-c0d2-4c84-adfb-493281880774, abstract = {Background- The inverse relationship between pulmonary function and incidence of cardiovascular disease remains largely unexplained. This prospective study explored the hypothesis of a relationship with inflammation-sensitive plasma proteins.,br/,,br, ,br/,,br, Methods and Results- Forced vital capacity (FVC) and plasma levels of fibrinogen, {alpha} 1-antitrypsin, haptoglobin, ceruloplasmin, and orosomucoid were determined in 5064 healthy men aged 28 to 61 years. All-cause mortality, cardiovascular mortality, and incidence of myocardial infarction were monitored over a mean follow-up period of 18.4 years. Low FVC (fourth quartile) was associated with higher protein levels and with increased incidences of myocardial infarction and cardiovascular death. Adjustments for protein levels reduced the age-adjusted relative risks (RRs) for myocardial infarction (from 1.99, 95% CI 1.5 to 2.6, to 1.70, 95% CI 1.3 to 2.2) and cardiovascular death ...
Iron and vitamin D deficiencies are common during pregnancy. Our aim was to identify whether antenatal vitamin D₃ supplementation affects iron status (via hepcidin suppression) and/or inflammation. Using a subset of the UK multicenter Maternal Vitamin D Osteoporosis Study (MAVIDOS)-a double-blinded, randomized, placebo-controlled trial (ISRCTN82927713; EudraCT2007-001716-23)-we performed a secondary laboratory analysis. Women with blood samples from early and late pregnancy (vitamin D₃ (1000 IU/day from ~14 weeks gestation n = 93; placebo n = 102) who gave birth in the springtime (March⁻May) were selected as we anticipated seeing the greatest treatment group difference in change in 25-hydroxyvitamin D (25OHD) concentration. Outcomes were hepcidin, ferritin, C-reactive protein, and α1-acid glycoprotein concentration in late pregnancy (25OHD concentration was measured previously). By late pregnancy, 25OHD concentration increased by 17 nmol/L in the vitamin D₃ group and decreased by 11 nmol/L in
Different RIA systems available for measuring the concentrations of pregnancy-associated glycoproteins (PAGs) in dairy goats were compared in order to evaluate their accuracy in early pregnancy diagnosis. Plasma concentrations of PAGs were determined
Rifampin is known to be an important stimulus to drug-metabolizing enzymes and can also induce the production of alpha 1-acid glycoprotein (AGP). We have studied the time course for induction of drug metabolizing capability as assessed by the clearance of antipyrine and the plasma concentration of AGP following a chronic course of rifampin in dogs. The kinetics of the induction process were observed during a 22-day treatment period, and the wash-out period kinetics were followed for another 3 weeks. Rifampin kinetics were measured at the end of the 22-day dosing period. Both antipyrine clearance and AGP concentration were significantly increased by the rifampin treatment; antipyrine clearance doubled and AGP concentrations nearly tripled. When analyzed by a newly developed kinetic model of induction, it was determined that the time course for AGP or antipyrine clearance was not governed by a single rate constant. The second rate constant did not represent the accumulation or persistence of ...
article{adc8b173-8290-4fe1-95e9-3dbfeae73d48, abstract = {Background- The extent to which differences in cardiovascular risk between smokers with similar daily tobacco consumption may be related to plasma levels of inflammation-sensitive proteins (ISP) and whether these proteins are associated with levels of carboxyhemoglobin (COHb%) have not been clarified.,br/,,br, ,br/,,br, Methods and Results- In a population-based cohort of 1489 never smokers, 1685 former smokers, and 2901 current smokers, aged 28 to 61 years, plasma levels of orosomucoid ({alpha}1-acid glycoprotein), {alpha}1-antitrypsin, haptoglobin, fibrinogen, and ceruloplasmin were measured. COHb% levels were available for 2098 of them. Incidence of myocardial infarction, stroke, and death were monitored over 18.7±4.7 years. The proportion with high ISP levels (ie, >=2 ISP in the top quartile) increased progressively with daily tobacco consumption (P<0.01) and COHb% (P<0.01). In all smoking categories, the incidence of ...
Twenty patients with invasive cervical cancer of the squamous cell type were treated by radiotherapy and/or radical hysterectomy. During a follow-up period of approximately 2 yr in 10 of these patients a recurrence was established. Serial determinations of three acute phase reactants (α1-acid glycoprotein, haptoglobin and C-reactive protein) and of ... read more three complement components (C4, C3-proactivator and C9) were performed before and after therapy and either at the time of recurrence (recurrence group), or at the end of the follow-up period (non-recurrence group). Sequential analysis of the serum levels of all the parameters tested showed a significant increase at the time of recurrence. The most conclusive results were obtained with haptoglobin and the C9-component of complement. show less ...
Toripristone (INN) (developmental code name RU-40555) is a synthetic, steroidal antiglucocorticoid as well as antiprogestogen which was never marketed. It is reported as a potent and highly selective antagonist of the glucocorticoid receptor (GR) (Ki = 2.4 nM), though it also acts as an antagonist of the progesterone receptor (PR). The pharmacological profile of toripristone is said to be very similar to that of mifepristone, except that toripristone does not bind to orosomucoid (α1-acid glycoprotein). The drug has been used to study the hypothalamic-pituitary-adrenal axis and has been used as a radiotracer for the GR. Its INN was given in 1990. Aglepristone Lilopristone Onapristone Telapristone R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. Murphy (23 May 1991). Dictionary of Steroids. CRC Press. pp. 101-. ISBN 978-0-412-27060-4. https://mednet-communities.net/inn/db/media/docs/p-innlist61.pdf Steiniger, Bjorn; Kniess, Torsten; Bergmann, Ralf; Pietzsch, Jens; Wuest, Frank (2008). "Radiolabeled ...
All reagents should be stored refrigerated (2-8°C). Return all reagents to 2-8°C promptly after use. Unopened reagents can be used for one year from the date of manufacture, as indicated by the expiration date on the package and bottle labels. Opened reagents can be used for one month if stored at 2-8°C ...
National Documentation Centre (EKT). National Archive of PhD Theses.PhD thesis.1986 . Creators: ΚΩΤΣΟΒΑΣΙΛΗΣ, ΚΩΝΣΤΑΝΤΙΝΟΣ.IN THE PRESENT STUDY THE DEGREE OF GLYCATION OF A1-ACID GLYCOPROTEIN (A1AGP) IN MALIGNANCY WAS INVESTIGATED BY THE METHOD OF AFFINITY IMMUNE ELECTROPHORESISIN TWO DIMENSIONS WITH CONCANAVALIN A IN THE FIRST DIMENSION. THE IMMUNOELECTROPHORETIC PATTERN OF A1AGP IN THE SERA FROM PATIENTS WITH VARIOUS NEOPLASTIC DISORDERS WAS INVESTIGATED TO DETERMINE WHETHER THE DEGREE OF GLYCATION OF A1AGP IS AFFECTED IN THE VARIOUS MALIGNANT GROUPS AND TO WHAT EXTENT THE CHANGES OBSERVED ARE CONSISTENT WITHIN A TUMOR GROUP AND CAN BE CHARACTERISTIC OF THE GROUP. THE TUMORS STUDIED WERE CLINICALLY CLASSIFIED INTO 11 GROUPS IN WHICH 8 DIFFERENT TYPES OF CHARACTERISTIC GLYCATION PATTERNS OF A1AGP HAVE BEEN RECOGNIZED. STATISTICAL ANALYSIS OF THE DATA BY CHI-SQUARE AND STUDENTS T-TEST PROVIDED FURTHER SUPPORT FOR THE SIGNIFICANCE OF THE FINDINGS ALREADY MENTIONED..
talk , contribs) (Created page with ==General== * Web-of-trust for packages ==Simplified JavaScript== ===Shared=== * XML parsing ===Plasmoid=== * Plasma::ToolTipManager * Expand/enrich config UI handling * Close ...) ...
AGP Pro = AGP On Steroids? - In recent tests we reviewed Motherboards with an AGP Pro slot. What is the beef about that feature? - This little article provides you with some technical specs of the AGP-Pro slot that can be found on several motherboards today.
asus geforce fx 5200 256mb agp card i want to know the shader model of the card :-2.0,3.0 or higher. because i need - ASUS GeForce FX5200 (64 MB) AGP question
So as Im filling up my pool I checked my numbers with a Walmart Test kit. My numbers are: 9 TC 8 PH 120ppm TA 120ppm TH CYA was so low the test failed twice. Any advice?
A rapid, specific radioimmunoassay has been used to measure Tamm-Horsfall glycoprotein (TH glycoprotein) in urine. The apparent concentration increased with increasing dilution of urine in water, reaching a plateau at 1 in 20. This increase was greater the higher the osmolality and TH glycoprotein concentration and the lower the pH of the original sample. A dilution of 1 in 100 was chosen for routine assay. Whole urine was centrifuged and the dissolved precipitate and supernatant assayed to quantify the proportion of TH glycoprotein of TH glycoprotein initially present in highly aggregated form. This correlated positively and significantly with increasing osmolality, decreasing pH and increasing TH glycoprotein concentration. When the urine was diluted 1 in 100 in water, no TH glycoprotein was precipitated by centrifugation and the measured concentrations were unaffected by alterations of urine pH or calcium concentration or by addition of sodium dodecyl sulphate. Parallelism was demonstrated ...
The relation between elevated ISPs and an increased incidence of acute coronary events is now well established. Whether the fatality of the events is related to the previous exposure to a low-grade inflammation has been unclear. In the entire cohort, the relative risks were higher for CHD deaths than for nonfatal MI. Among men who subsequently had acute coronary events, the number of elevated ISPs at baseline showed significant associations with the proportions of fatal outcomes (first day or within 28 days). The individual ISPs showed nonsignificant differences between CHD deaths and nonfatal MI. However, in accordance with many previous studies, the prognostic information increased substantially if all 5 ISPs were used.2,11,12,15 The results show that men who have been exposed to a low-grade inflammation many years earlier have higher fatality in future acute coronary events, with a higher proportion of CHD deaths and less nonfatal MI. If this finding can be replicated in other ...
TY - JOUR. T1 - Development of an affinity silica monolith containing α1-acid glycoprotein for chiral separations. AU - Mallik, Rangan. AU - Xuan, Hai. AU - Hage, David S.. PY - 2007/5/18. Y1 - 2007/5/18. N2 - An affinity monolith based on silica and containing immobilized α1-acid glycoprotein (AGP) was developed and evaluated in terms of its binding, efficiency and selectivity in chiral separations. The results were compared with data obtained for the same protein when used as a chiral stationary phase with HPLC-grade silica particles or monoliths based on a copolymer of glycidyl methacrylate (GMA) and ethylene dimethacrylate (EDMA). The surface coverage of AGP in the silica monolith was 18% higher than that obtained with silica particles and 61% higher than that measured for a GMA/EDMA monolith. The higher surface area of the silica monolith gave materials that contained 1.5- to 3.6-times more immobilized protein per unit volume when compared to silica particles or a GMA/EDMA monolith. The ...
The effects of the acute phase proteins AGP and AAT on early (2-hour) and late (24-hour) apoptosis and inflammation after renal I/R were investigated. Both AGP and AAT administered at reperfusion decrease early as well as late apoptosis, as reflected by renal internucleosomal DNA cleavage, TUNEL histology, and caspase-like activities. In line, we previously demonstrated that abrogating acute early apoptosis with selective antiapoptotic agents prevents subsequent inflammation as well as secondary apoptosis caused by inflammation, whereas antiapoptotic treatment that is initiated after the onset of apoptosis does not reduce I/R-induced inflammation.1 In contrast, in the present study, treatment after 2 hours of reperfusion inhibited inflammation, which is supported by reports of anti-inflammatory effects mediated by AGP and AAT.12 13 Early primary19 20 as well as late secondary2 21 apoptosis after I/R has been reported to be caused by various means. The present results, showing that AGP and (to a ...
This paper reports the first vibrational Raman optical activity (ROA) spectrum of a glycoprotein. The sample, orosomucoid (α1-acid glycoprotein), shows ROA bands characteristic of a high β-sheet content together with new bands which could be specific for the carbohydrate and its association with the protein. Our results suggest that ROA spectra of intact glycoproteins may contain information about both protein and carbohydrate conformation and the mutual influence on each others stability and conformation. ...
Asialoglycoprotein Receptor 1兔多克隆抗体(ab42488)可与大鼠, 人样本反应并经WB, ICC/IF实验严格验证,被2篇文献引用并得到2个独立的用户反馈。
The secondary pharmacokinetic quantities yielded by our model are in excellent agreement with the clinical observations of Burm et al.10 and Tucker.6,11 Very good agreement is also observed for the plasma concentration curve. Quantitative agreement is observed for the trend in plasma binding as a function of bupivacaine concentration. This is in contrast to the results obtained upon implementing the assumptions of Howell et al.17 , who reported a PBPK study of liposome-mediated toxicity reversal. A principal difference between their work and ours is the handling of protein binding. In their model, protein binding was treated as single site and concentration independent, rather than the explicit modeling of two distinct binding sites (α-1 acid glycoprotein and human serum albumin) that is employed here. While the protein-bound fraction of bupivacaine can be approximated as a constant for low blood concentrations, binding becomes nonlinear thereafter.9 For the low doses of bupivacaine employed in ...
Rabbit Polyclonal Anti-Asialoglycoprotein Receptor 2 Antibody. Validated: WB, IHC, IHC-P. Tested Reactivity: Human. 100% Guaranteed.
Results A panel of 107 proteins was selected, and targeted mass spectrometry MRM assays were successfully developed for 57 of the proteins. The 57 proteins include S100-A8, S100-A10, Ig kappa chain C fibrinogen-α and γ, haptoglobin, annexin A1 and A2, collagen alpha-2, vitronectin, and alpha-1 acid glycoprotein. The proteins were measured simultaneously and confirmed to be predictive of response to treatment with an area under the curve of 0.76. In a blinded study using a separate cohort of patients, the panel was able to predict response to treatment.. ...
adeelarshad82 writes For a second year in a row PCMag partnered with Speedtest to find out the fastest ISPs in the U.S. The results were a product of 110,000 tests ran between January 1, 2012 and September 19, 2012. Collecting data for both download and upload speeds for each test, Speednet was abl...
Looking for online definition of Acute phase reactant in the Medical Dictionary? Acute phase reactant explanation free. What is Acute phase reactant? Meaning of Acute phase reactant medical term. What does Acute phase reactant mean?
TY - JOUR. T1 - Asialoglycoprotein receptor phosphorylation and receptor-mediated endocytosis in hepatoma cells. Effect of phorbol esters. AU - Fallon, R. J.. AU - Schwartz, A. L.. PY - 1988/1/1. Y1 - 1988/1/1. N2 - The asialoglycoprotein (ASGP) receptor on Hep G2 cells undergoes constitutive recycling and ligand endocytosis in the presence of phorbol dibutyrate, at a 50% reduced rate relative to control cells (Fallon, R. J., and Schwartz, A. L. (1986) J. Biol. Chem. 261, 15081-15089). The relevance of receptor phosphorylation to these events was investigated by selective immunoprecipitation of surface receptors with polyclonal anti-human ASGP antiserum and pulse-chase labeling with [32P]orthophosphate to identify subcellular locations of initial receptor phosphorylation events as well as the eventual fate of phosphorylated receptor during recycling. The surface immunoprecipitation method recovers greater than 95% of surface ASGP receptors and only 5% or less of intracellular ...
Abstract. Abstract 1868Background. ARRY-520 is a kinesin spindle protein (KSP) inhibitor that has demonstrated clinical activity in patients with relapsed and
DNA molecules complexed with an asialoglycoprotein-polycation conjugate, consisting of asialoorosomucoid (ASOR) coupled to poly-l-lysine, can enter hepatocytes which bear receptors for ASOR. We used this receptor-mediated DNA delivery system to deliver plasmid DNA encoding glycoprotein D (gD) of herpes simplex virus type 1 to ASOR-positive cells. Maximum expression of gD protein was seen at 3 days after injection of this preparation in approximately 13% of cells from BALB/c mice [hepatocytes from mice injected intravenously (i.v.) or peritoneal exudate cells from mice injected intraperitoneally (i.p.)]. In comparison with mice injected with either the plasmid vector alone or the gD-containing plasmid uncomplexed to ASOR, mice immunized with gD-containing plasmid complexed with ASOR-poly-l-lysine induced marked antigen-specific CTL responses. BALB/c mice immunized with gD-DNA developed a T-cell-mediated CTL response against target cells expressing gD and MHC class II glycoproteins, but not against cells
The LEGENDplex™ Human Acute Phase Panel 1 (8-plex) contains fluorescence-encoded beads suitable for use on common flow cytometers. It allows for the simultaneous quantification of 8 key acute phase molecules including α2-microglobulin, α1-acid glycoprotein (α1-AGP), Haptoglobin, α1-antitrypsin, Ceru
AGP1 - Iron is the purest and most advanced Colloidal Iron that utilised the latest Nano-technology. It is sourced from the remains of an ancient rainforest which contains the most active plant-based element from the nature.. ...
Hey guys. Help me out here. I need a decent AGP card for my brother in laws system. If I dont help him out, hes gonna go to Best Buy and spend a fortune...
Hey guys,I am considering getting a 6800GT, and there seems to be quite a few between $390-$400. Which of the following brands do you most recommend and which would you suggest to steer away from?The...