Kansanen E. Kuosmanen SM. Ruotsalainen AK. Hynynen H. Levonen AL. (2017). Nitro-Oleic Acid Regulates Endothelin Signaling in Human Endothelial Cells. MOLECULAR PHARMACOLOGY, 92 (4) , 481-490. 10.1124/mol.117.109751. ...
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.It also finds use as a lubricant and a plasticizer.Ethyl oleate is regulated as a food additive by the Food...
EWGs Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases.
Oleamide works as a health promoting, calming dietary supplement. Its great for improving sleep and promoting a restful, relaxed state. Learn more here!
TY - JOUR. T1 - Melittin-mediated release of [3H]-oleic acid from E. coli cells is dependent upon heat- and trypsin-sensitive factor(s) in human serum. AU - Saini, Shamsher S.. AU - Chopra, Ashok. AU - Peterson, Johnny. PY - 2000/8/1. Y1 - 2000/8/1. N2 - Synthetic melittin mediated the release of [3H]-oleic acid ([3H]-OA) or its acylated lipids from [3H]-OA-labeled E. coli cells exposed to human serum. This phenomenon was not observed in the absence of serum and was calcium independent. The addition of serum was not required for melittin-mediated lysis of erythrocytes, although lysis was greater in the presence of serum than in its absence (P,0.001). Trypsin treatment of human serum reduced the melittin-mediated release of [3H]-OA/acylated lipids, and this effect was more pronounced upon boiling the serum (P,0.01). A kinetic study showed that maximum release of [3H]-OA/acylated lipids occurred within 3-6 min. Thin layer chromatography (TLC) analysis showed the lipids to be phosphatidyl ...
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Promotes Solder Flow and Adhesion. Prevents Oxidation. This CRL Oleic Acid is a soldering flux that cleans the surface and promotes solder flow. Designed to be brushed on with a Acid Brush prior to soldering. This product makes solder adhere better and prevents oxidation. oleic acid msds, oleic acid
Estolides are a group of FA polyesters resulting from ester bond formation between a hydroxyl or olefinic group of one FA and the terminal carboxyl group of a second FA. These products are commonly found in trace amounts, forming tetraglycerides in several oil seed plants, and have been produced by acid clay and enzymatic catalysis in vitro. In this study, natural estolides produced by a bacterial culture are presented for the first time. Pseudomonas sp. 42A2 produced (E)-10-hydroxy-8-octadecenoic acid and (E)-7,10-dihydroxy-8-octadecenoic acid when grown on oleic acid. It is suggested that these FA were polymerized in culture by a lipase produced by the bacterial strain, resulting in a mixture of estolides. These compounds amounted to 3.8 g/L after 72 h of incubation. LC-MS analysis indicated that the types of estolides formed were dimers (m/z 560-610), trimers (m/z 845-906), tetramers (m/z 1122-1202), pentamers (m/z 1328-1424), and hexamers (m/z 1554-1788), with a relative abundance of 27.5, ...
The unsaturated fatty acid-requiring mutant KD 115 of Saccharomyces cerevisiae secretes a lectin when grown in presence of oleic acid. This lectin is homogeneous on PAGE at pH 8.3, has an approximate molecular weight of 320,000, pI of 4.2 and contains about 60% sugar. It agglutinates chicken and different mammalian erythrocytes, but lyses rabbit red cells only. It is D-galactose-specific. To our knowledge, this is the first report of a hemagglutinin from yeast. ...
MON 87705 has been transformed with a DNA sequence to perform three novel functions. One is the customary tolerance to Roundup herbicide which comes from a bacterial gene linked to DNA to activate it in the green parts of the plant. The other two work together to cause oleic acid to accumulate. These are re-jigged soya DNA sequences which generate factors to alter the plants fat metabolism: one of these factors blocks the enzyme which would normally channel oleic acid away from its site of production to elsewhere in the cell for further processing; the other factor suppresses the normal onward conversion of oleic acid to other fatty acids. These factors are linked to DNA which activates them in the seed. Between them, the two blocking mechanisms cause the GM soyabeans accumulate a huge and unnatural amount of oleic acid. The knock-on effect is that very little linoleic acid and very little of the saturated acids, palmitic and stearic acids, are produced. MON 87705 has, however, the usual amount ...
Oleic acid is an omega-9 fatty acid commonly found in plant and animal products thats known for many health benefits. Oleic acid supports cellular health, brain function and more.
Pharmaceutical formulations and methods including an immune response modifier (IRM) compound and an oleic acid component are provided where stability is improved by using oleic acid have low polar impurities such as peroxides.
Q: How much palmitic acid is in Omega-7 Support Gels?. A: The total amount of palmitic acid in a dose of Omega-7 Support Soft Gels is slightly less than 1% of the daily maximum limit the WHO (World Health Organization) recommends. One dose of the SIBU soft-gels contains about 40% Omega 7 (mostly palmitoleic acid and a little cis-vaccenic acid). Palmitic acid is bad in large quantities (as in most American diets) but 1 dose of 1000mg of SIBU soft-gels contains less than 1% of the recommended daily maximum so its negligible.. Q: Whats the daily recommended dose for the Omega-7 Support Gels? A: The daily recommended dose for the Omega 7 Support is 2 500mg soft gels/day. Be sure to check with your doctor about Omega 7s possible effects on your body before you begin. Q: Whats the daily recommended dose for SIBUs Omega-Pure?. A: We recommend starting with 1 oz. per day. You can slowly increase from there up to 4 oz a day.. Q: Can Omega-7 Supplements help you lose weight? A: While Omega 7 doesnt ...
Read "Synthesis of PNIPAM-PEG Double Hydrophilic Polymers Using Oleic Acid Macro Peroxide Initiator, Journal of the American Oil Chemists
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250 µCi quantities of [1-14C]-Oleic Acid are available for your research. Application of [14C]Oleic Acid can be found in: trans-10, cis-12 conjugated linoleic acid decreasing de novo lipid synthesis in human adipocytes, effect of dietary phosphatidylcholine on the assimilation and distribution of ingested free oleic acid in aquaculture, variation of liver-type fatty acid binding protein content in the human HepG2 affecting the rate of fatty acid uptake, oleic acid stimulating rapid translocation of cholinephosphate cytidylyltransferase in type II cells, intestinal-fatty acid binding protein (I-FABP) and lipid transport in human intestinal epithelial cells, etc. ...
Near infrared reflectance spectra (NIRS) was collected from Arachis hypogaea seed samples and used in predictive models to rapidly identify varieties with high oleic acid. The method was developed for shelled peanut seeds with intact testa. Spectra was evaluated initially by principal component analysis (PCA) followed by partial least squares (PLS). PCA performed with full spectra and reduced spectra with one principal component accounted for 97% to 99% variability, respectively. The PLS model generated from first derivative spectra provided a standard error of prediction (SEP) of 7.7204808. This technique provides a non-destructive method to rapidly identify high oleic peanut seeds to support the selection and cultivation of high oleic acid peanut varieties. The method can also be useful at peanut processing facilities for screening and quality assessments.
TY - JOUR. T1 - Mechanisms of vasorelaxation induced by oleoylethanolamide in the rat small mesenteric artery. AU - Alsuleimani, Yousuf M.. AU - Hiley, C. Robin. PY - 2013/2/28. Y1 - 2013/2/28. N2 - The actions of the anandamide-like mono-unsaturated fatty acid oleoylethanolamide (OEA) were first linked to satiety and control of food intake and recently reported to relax resistance vessels. This study characterizes its vasorelaxant mechanisms. Vasorelaxation to OEA were assessed in third order branches of rat superior mesenteric artery using a wire myograph. The roles of the endothelium, KCa channels, perivascular sensory nerves, NO, cannabinoid receptors, and the phospholipase C (PLC)/inositol trisphosphate (InsP3) and RhoA/ROCK signalling pathways, were assessed. OEA caused concentration- and endothelium-dependent vasorelaxation (pEC50=6.7±0.1, Rmax=93.1±2. 5%). L-NAME greatly reduced the response (residual relaxation of only 24.6±12.8%). Capsaicin and pertussis toxin significantly reduced ...
ACME SYNTHETIC CHEMICALS - Exporter, Manufacturer, Supplier, Trading Company of Oleic Acid Ethyl Ester - Manufacturer based in Mumbai, India
Development policies and plans are also discussed as well as manufacturing processes and cost structures. Oleic Acid (CAS 112-80-1) market report also states import/export, supply and figures as well as cost, price, revenue and gross margin by regions (United States, EU, China and Japan), and other regions can be added.. Then, Oleic Acid (CAS 112-80-1) market report focuses on major leading industry players with information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials, and downstream consumers analysis is also carried out. Whats more, the Oleic Acid (CAS 112-80-1) industry development trends and marketing channels are analysed.. For each player, product details, capacity, price, cost, gross and revenue numbers are given. Their contact information is provided for better understanding.. Finally, the feasibility of new investment projects is assessed, and overall research conclusions are ...
Detailed Ethanolamine Oleate dosage information for adults. Includes dosages for Esophageal Varices; plus renal, liver and dialysis adjustments.
Sigma-Aldrich offers abstracts and full-text articles by [B Kollbe Ahn, Jonggeun Sung, Yonghui Li, Namhoon Kim, Myles Ikenberry, Keith Hohn, Nihar Mohanty, Phong Nguyen, T S Sreeprasad, Stefan Kraft, Vikas Berry, Xiuzhi Susan Sun].
EXPELLER PRESSING- Oils labeled expeller pressed use a mechanical method to extract food oils. Not only is this method more natural because it does not use harsh chemicals like hexane but it also leaves us with a much more stable and quality oil.. HIGH OLEIC- Hi Oleic oils have a unique nutrition profile that features high oleic acid and low linolenic acid. Hi Oleic oils are typically low in saturated fats and are known for their versatility and natural stability. For operators or manufactures these oils present some of the most cost effective solutions to manage oil costs.. NON-GMO- Products labeled NON-GMO are manufactured using ingredients that are not grown using genetic engineering or gene splicing. Producing NON-GMO products requires preserving the NON-GMO identity through every stage of production. All NON-GMO and Organic products from Healthy Brand Oil take these measures.. OSI- Oil Stability Index (OSI) is an industry standard method to determine the shelf stability of edible ...
Oleoylethanolamide (OEA) is an agonist of the peroxisome proliferator-activated receptor α (PPARα) and has been described to exhibit neuroprotective properties when administered locally in animal models of several neurological disorder models, including stroke and Parkinsons disease. However, there is little information regarding the effectiveness of systemic administration of OEA on Parkinsons disease. In the present study, OEA-mediated neuroprotection has been tested on in vivo and in vitro models of 6-hydroxydopamine (6-OH-DA)-induced degeneration. The in vivo model was based on the intrastriatal infusion of the neurotoxin 6-OH-DA, which generates Parkinsonian symptoms. Rats were treated 2 h before and after the 6-OH-DA treatment with systemic OEA (0.5, 1, and 5 mg/kg). The Parkinsonian symptoms were evaluated at 1 and 4 wk after the development of lesions. The functional status of the nigrostriatal system was studied through tyrosine-hydroxylase (TH) and hemeoxygenase-1 (HO-1, oxidation ...
At NYSCC Suppliers Day 2013, Beraca will introduce two new products to the U.S. personal care market: a anti-inflammatory active and a moisturizing oil with high oleic acid content.
68154-55-2 - Fatty acids, C18-unsatd., dimers, polymers with diethylenetriamine, ethylenediamine and oleic acid - Searchable synonyms, formulas, resource links, and other chemical information.
Surface active compounds present in food possibly have the ability to enhance the absorption of water soluble toxic agents. Therefore, we investigated whether fatty acids such as oleic acid and docosahexaenoic acid (DHA), both commonly present in food, negatively affect the integrity of tight junctions (TJ) in the intestinal epithelium and thereby increase the absorption of poorly absorbed hydrophilic substances. Caco-2 cells, which are derived from human absorptive enterocytes, were grown on permeable filters for 20-25 days. Differentiated cell monolayers were apically exposed for 90min to mannitol in emulsions of oleic acid (5, 15 or 30mM) or DHA (5, 15 or 30mM) in an experimental medium with or without Ca(2+) and Mg(2+). Absorption of (14)C-mannitol increased and trans-epithelial electrical resistance (TEER) decreased in cell monolayers exposed to oleic acid and DHA, compared to controls. Cytotoxicity, measured as leakage of LDH, was higher in groups exposed to 30mM oleic acid and all ...
article{5f5f6d98-011d-45d8-9728-f5a50aecaf3b, abstract = {HAMLET (human -lactalbumin made lethal to tumor cells) is a complex of human -lactalbumin and oleic acid (C18:1:9 cis) that kills tumor cells by an apoptosis-like mechanism. Previous studies have shown that a conformational change is required to form HAMLET from -lactalbumin, and that a partially unfolded conformation is maintained in the HAMLET complex. This study examined if unfolding of -lactalbumin is sufficient to induce cell death. We used the bovine -lactalbumin Ca2+ site mutant D87A, which is unable to bind Ca2+, and thus remains partially unfolded regardless of solvent conditions. The D87A mutant protein was found to be inactive in the apoptosis assay, but could readily be converted to a HAMLET-like complex in the presence of oleic acid. BAMLET (bovine -lactalbumin made lethal to tumor cells) and D87A-BAMLET complexes were both able to kill tumor cells. This activity was independent of the Ca2+site, as HAMLET maintained a high ...
Decision Document 2001-34: Determination of the Safety of Optimum Quality Grains L.L.C.s High Oleic Soybean (Glycine max) line G94-1, G94-19, and G-168 Derived from Transformation Event Line 260-05
HAMLET carries out independent attacks on many distinct cell organelles, including mitochondria, proteasomes, and histones, and interferes with cell processes such as macroautophagy. It has been shown that HAMLET binds to the cell surface and rapidly invades cells, with tumor cells taking up far more protein than healthy, differentiated cells. The mechanism of its entry is poorly understood, but recent studies indicate that the oleic acid in the HAMLET complex interacts with phosphatidylserine and o-glycosylated mucin on the plasma membrane, both of which are expressed in greater amounts on the plasma membrane of tumor cells, possibly providing for HAMLETs specificity.[6] One of the most prominent targets of HAMLET once inside the cell is the mitochondrion. Electron microscopy has revealed physical damage to the mitochondrial membranes and assays have found cytochrome c release and activation of the caspase cascade, the most notable ones being caspases 2, 3, and 9.[7] Cell death is not ...
Fatty acids are organic acids which have a long chain of carbon and hydrogens attached to the carboxyl group. Oleic Acid is a common saturated fatty acid. Actually the bend in the carbon chain suggests that oleic acid is not completely saturated. ...
... from SCD blockade had been completely reversed by either oleic (18:1n-9), palmitoleic acidity (16:1n-7) or cis-vaccenic acidity (18:1n-7) showing that cis-MUFA are essential elements for cancers cell growth. Additionally, co-treatment of cells with CVT-11127 and CP-640186, a particular acetylCoA carboxylase (ACC) inhibitor, do not really potentiate the development inhibitory impact of these substances, recommending that inhibition of SCD1 or ACC impacts a equivalent focus on important for cell growth, most likely MUFA, the common fatty acidity item in the path. This speculation was additional strengthened by the remark that exogenous oleic acidity reverses the anti-growth impact of SCD and ACC inhibitors. Cediranib Finally, exogenous oleic acidity refurbished the internationally reduced amounts of cell fats in cells going through a blockade of SCD activity, suggesting that energetic lipid activity is definitely needed for the ...
Sructure images and info for more than 300 fatty acids. Find species that produce a fatty acid, publications, data and phylogenetic distribituion of plants that produce a fatty acid.
Progesterone in sesame oil, olive oil, ethyl oleate; progesterone suppositories; Crinone - Ive been on it all and had plenty of the little disasters that accompany them. Follow me in the next couple of posts as I explain the good, the bad, and the ugly.
kita kualitas baik Produk Perawatan Kesehatan Kimia, bahan tambahan surfaktan Pelumas Ethyl Oleate CAS 111-62-6 produsen & eksportir - Beli Bedak Pertumbuhan Rambut dari Cina pabrik.
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decreases the transport of saturated fatty acids out of the plastid, thereby increasing their availability to desaturation to 18:1 oleic acid; reduces the levels of saturated fatty acids and increases the levels of 18:1 oleic ...
decreases the transport of saturated fatty acids out of the plastid, thereby increasing their availability to desaturation to 18:1 oleic acid; reduces the levels of saturated fatty acids and increases the levels of 18:1 oleic ...
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Extraction: esterified glycerin with a mixture of citric, lactic, linoleic and oleic acid. This ingredient is of vegetable origin. Benefits: acts as a lubrican
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Nitro-fatty acids (NO(2)-FA) are electrophilic signaling mediators formed by reactions of nitric oxide and nitrite. NO(2)-FA exert anti-inflammatory signaling actions through post-translational protein modifications. We report that nitro-oleic acid (OA-NO(2)) stimulates proMMP-7 and proMMP-9 proteolytic activity via adduction of the conserved cysteine switch domain thiolate. Biotin-labeled OA-NO(2) showed this adduction occurs preferentially with latent forms of MMP, confirming a role for thiol alkylation by OA-NO(2) in MMP activation. In addition to regulating pro-MMP activation, MMP expression was modulated by OA-NO(2) via activation of peroxisome proliferator-activated receptor-γ. MMP-9 transcription was decreased in phorbol 12-myristate 13-acetate-stimulated THP-1 macrophages to an extent similar to that induced by the peroxisome proliferator-activated receptor-γ agonist Rosiglitazone. This was affirmed using a murine model of atherosclerosis, ApoE(-/-) mice, where in vivo OA-NO(2) administration
This page contains abstract Effects of Gamma-linolenic Acid and Oleic Acid on Paclitaxel Cytotoxicity in Human Breast Cancer Cells http://www.chiro.org/nutrition/ABSTRACTS/Effects_of_Gamma_linolenic_Acid.shtml
Sarver R.W., Gao H., Tian F.. An NMR method was developed for determining binding sites of small molecules on human serum albumin (HSA) by competitive displacement of (13)C-labeled oleic acid. This method is based on the observation that in the crystal structure of HSA complexed with oleic acid, two principal drug-binding sites, Sudlows sites I (warfarin) and II (ibuprofen), are also occupied by fatty acids. In two-dimensional [(1)H,(13)C]heteronuclear single quantum coherence NMR spectra, seven distinct resonances were observed for the (13)C-methyl-labeled oleic acid as a result of its binding to HSA. Resonances corresponding to the major drug-binding sites were identified through competitive displacement of molecules that bind specifically to each site. Thus, binding of molecules to these sites can be followed by their displacement of oleic acids. Furthermore, the amount of bound ligand at each site can be determined from changes in resonance intensities. For molecules containing fluorine, ...
Elaidic acid is the main unnatural trans fatty acid isomer occurring during partial hydrogenation of vegetable oils used as ingredients for the formulation of processed foods. The main objective is to assess associations between processed food intakes and plasma phospholipid elaidic acid concentrations within the European Prospective Investigation into Cancer and Nutrition study. A cross-sectional study was used to determine fatty acid profiles in 3,003 subjects from 16 centers. Single 24-h dietary recalls (24-HDR) were collected using a standardized computerized interview program. Food intakes were computed according to their degree of processing (moderately/nonprocessed foods, processed staple foods, highly processed foods). Adjusted ecological and individual correlations were calculated between processed food intakes and plasma elaidic acid levels. At the population level, mean intakes of highly processed foods were strongly correlated with mean levels of plasma elaidic acid in men (P = ...
ACME SYNTHETIC CHEMICALS - Exporter, Manufacturer, Supplier, Trading Company of Oleic Acid Ethyl Ester - Pharmaceutical Chemical based in Mumbai, India
Soybean 305423 was developed through particle bombardment and contains gm-fad2-1 and gm-hra expression cassettes, conferring a high oleic acid profile and tolerance to acetolactate synthase (ALS)-inhibiting herbicides. Bioinformatic analyses and genetic stability studies did not raise safety issues. Levels of the GM-HRA protein in soybean 305423 have been sufficiently analysed. Soybean 305423 differs from the conventional counterpart in the seed fatty acid profile and for the presence of the GM-HRA protein. It is agronomically equivalent to non-GM reference soybeans. The safety assessment of GM-HRA identified no concerns regarding potential toxicity and allergenicity. There are no indications that the overall allergenicity of soybean 305423 has changed. Nutritional assessment on soybean 305423 oil and derived food products did not identify concerns on human health and nutrition. There are no concerns regarding the use of feeding stuffs derived from soybean 305423. There are no indications of an ...