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trigger point therapy and shiatsu. Another smart idea is to have your friend or spouse or relative apply the cream on your behalf. While they apply it have them integrate some trigger point therapy or muscles stripping as they rub you. Massaging releases small amounts of endorphins, which ease pain. Endorphins have no side effects.. When purchasing any pain relief cream, take a closer look at the ingredients. There is no magic pill or cream that takes the pain away permanently. If you have no known reactions to ibuprofen (which helps temporarily reduce inflammation), then consider making your own topical cream by mixing ground ibuprofen and the right amount of menthol. Unfortunately ibuprofen cream is not approved for sale in the United States. I found a book that includes detailed instruction on making your own topical creams, called If You Can Cook, You Can Make… Powerful Topical Remedies For Hair Loss, Pain And Herpes Infections.. If you like that cooling and heating sensation then a ...
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General Procedure: Subjects will be screened for: a history of knee pain and surgery by questionnaire; kidney disease as determined by blood creatinine levels; knee diameter less than 17cm and body diameter less than 60 cm due to the physical constraints of the MRI. Prior X-rays or MRIs will be examined to evaluate the subjects level of OA. X-rays and MRIs that are older than 2 years, cannot be used and these potential subjects will receive one set of 2 knee x-rays prior to enrollment. If they qualify and wish to enroll, they will be matched on age, sex and degree of OA and assigned by a 3rd party investigator to either a placebo group or active treatment group. Subjects will be asked to complete baseline questionnaires, functional tests, and have blood draws and MRI screenings before starting their treatment. Enrolled subjects will apply 2.5 grams of active or placebo cream 3 times per day to the skin over the affected knee for 12 weeks. Further measurements will be taken periodically ...
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