Practical and objective instruments to assess pediatric Crohns disease (CD) activity are required for observational research and quality improvement. The objectives were: 1) to determine the feasibility of completing the Pediatric Crohns Disease Activity Index (PCDAI) and the Abbreviated PCDAI (APCDAI); and 2) to create a Short PCDAI by retaining and reweighting the most practical and informative components.
This study showed that, apart from individual factors such as parental education level, certain modifiable characteristics in the neighborhood environment (as measured by neighborhood observations) were associated with outdoor play among boys and girls of different age groups in The Netherlands. The finding that parental education level was negatively associated with outdoor play, might be explained by the fact that higher educated parents have more financial resources for organized sports activities, and that this substitutes time spent on outdoor play [30]. Moreover, as lower educated parents might live in smaller houses, this makes it more likely for children to play outdoors. Another explanation might be found in the finding that parents living in more socioeconomic deprived areas are more likely to allow their children to take part in outdoor activities independently [31]. Veitch et al. recently have shown that the correlation between parental education level and the time spent on outdoor ...
In the present study, perception of limitations in the activities of daily life after uVN were measured using the DHI 17. The average DHI (38.52) in the 1st test corresponded to the results of previous studies for acute uVN (range: 37-45) 18-20. DHI improved significantly between the 1st and the 2nd tests. Although the DHI improved between the 2nd and 3rd tests, the difference was not statistically significant. We speculate that statistical insignificance between the 2nd and 3rd tests resulted from the large inter-personal variations. Considering DHI scores less than 5 in the control group 20, these findings suggest that the perception of limitation in the activities of daily life after uVN persists after 3 months of onset and support a previous study result that DHI improved to near normal values after 6 months 19. The results of the vestibular score and composite score from the CDP showed significant improvements between the 1st and 2nd tests. Compared to the normal reference values 21, the ...
An opening ceremony was held April 28 to kick off the second phase of construction of Laos 1,156-MW Nam Ou River Basin Hydropower Project, according to Vientiane Times.. During the first phase, construction was completed on the Nam Ou 2, Nam Ou 5 and Nam Ou 6 plants. The first unit began generating electricity in November 2015, according to owner and developer Sinohydro. Together they have a total capacity of 540 MW and annual electricity output of 2,092 million kWh. Construction on these facilities began in October 2012. The second phase involves building the Nam Ou 1, Nam Ou 3, Nam Ou 4 and Nam Ou 7 projects.. The project is on the Nam Ou River in the provinces of Phongsaly and Luang Prabang. In total it will feature seven dams and powerhouses with a projected capacity of 1,156 MW and annual energy output of 5,017 GWh. Total cost is expected to be US$2.8 billion, and work on the second phase is estimated to be complete in 2020.. After a 29-year concession period, which as best we can ...
Highland Hospitals Observation Unit is designed to provide high-quality, personalized care for patients who require evaluation and treatment for a period of time between eight and 24 hours. Some conditions that may require observation include chest pain, dehydration, asthma, abdominal pain, kidney stones, and minor infections. Our staff closely monitors the conditions of our patients and streamlines their testing and treatment which may include intravenous fluids, pain medication and/or antibiotics.. The Observation Unit has been recently renovated and is adjacent to, but separate from the Emergency Department. The rooms are private and each has a television and a phone. Meals are served to patients whose condition permits them to eat. Patients whose conditions improve or can be managed at home will be discharged, along with a plan for appropriate care. Patients whose conditions fail to improve or worsen will be admitted to the hospital for further care.. Our patient care team includes ...
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Several community-based cohort studies have been funded by the National Institutes of Heath and other funding agencies. These studies have the ability to evaluate renal function and progression of disease. The National Heart, Lung, and Blood Institute has funded several cohort studies that have provided important insights in kidney disease. These cohorts include the Framingham Heart Study, Cardiovascular Heath Study (CHS), Atherosclerosis Risk in Communities study (ARIC) and the Coronary Artery Risk Development in Young Adults study (CARDIA). The last three recruited participants with distinct age groups at entry: CHS included people who were older than 65 yr, ARIC enrolled adults aged 45 to 64 yr, and CARDIA targeted young adults aged 18 to 30 yr.. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has supported several cohort studies in clinical populations with kidney disease. These studies include the Choices for Healthy Outcomes in Caring for End-Stage Renal ...
Meta-analysis typically involves combining the estimates from independent studies in order to estimate a parameter of interest across a population of studies. However, outliers often occur even under the random effects model. The presence of such outliers could substantially alter the conclusions in a meta-analysis. This paper proposes a methodology for identifying and, if desired, downweighting studies that do not appear representative of the population they are thought to represent under the random effects model. An outlier is taken as an observation (study result) with an inflated random effect variance. We used the likelihood ratio test statistic as an objective measure for determining whether observations have inflated variance and are therefore considered outliers. A parametric bootstrap procedure was used to obtain the sampling distribution of the likelihood ratio test statistics and to account for multiple testing. Our methods were applied to three illustrative and contrasting meta-analytic data
The treatment of early-stage Hodgkin lymphoma remains controversial with combined modality therapy and chemotherapy alone representing acceptable options. Observation studies show a progressive decline in the use of radiation secondary to late complications but also suggest a decrease in survival for non-irradiated patients. Early PET CT scans have been incorporated into strategies of response-adapted therapy but have been imperfect in identifying patients who may require more aggressive treatment. In the absence of radiation, further improvement in the cure rate is likely to require better chemotherapy such as the incorporation of two cycles of dose-escalated BEACOPP or possibly the substitution of brentuximab for bleomycin. The treatment of patients who have relapse after abbreviated chemotherapy alone is not standardized and it remains unclear whether these patients should all receive highdose chemotherapy and autologous stem cell rescue or whether a significant fraction can be salvaged with
A Prospective Observational Study on Pattern, Severity and Outcome of Different Poisoning Cases in a Tertiary Care Hospital, India, Vijay Mate
The Surgical Observation Unit (SOU) is a specialized area designed to meet the needs of patients who physicians determine should stay for a short time in post-surgical care. Patients may also be admitted to the SOU while waiting to be transferred to a regular hospital room.
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Le présent communiqué et les informations quil contient ne constituent pas, ni ne sauraient être interprétés comme une offre au public ou une invitation de vente ou de souscription, ou la sollicitation de tout ordre ou invitation dachat ou de souscription dactions PIXIUM VISION dans un quelconque pays. La diffusion de ce communiqué dans certains pays peut constituer une violation des dispositions légales en vigueur. Les personnes en possession du communiqué doivent donc sinformer des éventuelles restrictions locales et sy conformer.. En particulier, le présent communiqué ne constitue pas une offre de vente de valeurs mobilières ou une quelconque sollicitation doffre dachat ou de souscription de valeurs mobilières aux Etats-Unis. Les actions, ou toute autre valeur mobilière, de PIXIUM VISION ne peuvent être offertes ou vendues aux Etats-Unis quà la suite dun enregistrement en vertu du U.S. Securities Act de 1933, tel que modifié (« U.S. Securities Act de 1933 »), ou ...
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TORAH TIDBITS: WEEKLY TORAH PUBLICATION IN ENGLISH. OU Israel publishes Torah Tidbits, the largest weekly English-language Torah publication in Israel.. It reaches an estimated 30,000 readers in almost every English-speaking community in Israel. - and, via the internet - around the world.. It features a summary of the weekly Torah portion, Divrei Torah, questions and answers about Halachic issues, and inspirations articles on various topics by well-known rabbis.. Torah Tidbits also publishes a schedule of all activities sponsored by the OU Israel Center. Advertisements and notices are geared for the English-speaking community in Israel.. Online and email versions are available.. Click on the link below for many online and downloadable options. http://www.torahtidbits.com/. You can also link to Torah Tidbits Audio, a weekly internet-radio show.. ...
Dr. Jennifer Ahern is Associate Dean for Research and Professor of Epidemiology at the University of California, Berkeley, School of Public Health. She examines the effects of the social and physical environment, and programs and policies that alter the social and physical environment, on many aspects of health (e.g., violence, substance use, mental health, and gestational health). Dr. Ahern has a methodological focus to her work, including the application of causal inference methods and semi-parametric estimation approaches, aimed at improving the rigor of observational research, and optimizing public health intervention planning. Her research has been supported by a New Innovator Award from the National Institutes of Health (NIH), Office of the Director. ...
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Prognosis research has been defined as the study of relations between occurrences of outcomes and predictors in defined populations of people with disease.1 It encompasses (ideally) prospective, observational research evaluating three broad questions-causes of disease progression, prediction of risk in individuals, and individual response to treatment. High quality prognosis research results in better understanding of disease progression, offers improved opportunities for mitigating that progression, and allows more reliable communication of outcome risk to patients.1 2 Prognosis research should be a basic science in translational medicine.. Analysing 168 reports, Malats and colleagues concluded that after 10 years of research [including over 10 000 patients], evidence is not sufficient to conclude whether changes in P53 act as markers of outcome in patients with bladder cancer.3 This is not an isolated example. Such concerns have been identified in systematic reviews of different types of ...
Medical marijuana is authorized in several states and can provide benefits for people with a wide variety of medical points. Several randomized scientific trials and one large inhabitants observational research utilizing digital interventions have demonstrated favorable outcomes amongst diverse and common situations, resembling bronchial asthma, heart failure, diabetes, and cancer ( 7 , 8 ). For example, in a study in Louisville, Kentucky, using inhalers that transmit knowledge wirelessly led to a 48{cf96bdc97c7c61df95da16e139acb3961534b4f140262e072d52a16c45423376} reduction in asthma attacks and a seventy eight{cf96bdc97c7c61df95da16e139acb3961534b4f140262e072d52a16c45423376} reduction within the need for rescue inhaler use ( 7 ). Within the Telemedical Interventional Management in Heart Failure II (TIM-HF2) trial, there was a 20{cf96bdc97c7c61df95da16e139acb3961534b4f140262e072d52a16c45423376} reduction within the percentage of days misplaced as a result of unplanned cardiovascular hospital ...
Scientific research can be usefully divided according to the material it has to deal with; these categories are observational research and experimental research. In the former, man and his methods can only interpret phenomena as they reach him, without ability to manipulate the phenomena. This is the case for astronomy, for example. This is also the case for epidemiologic studies, in which relationships of various factors are sought in populations, or for pathology studies in which morphologic appearance of tumors is related to the eventual clinical course of the patient. In experimental research, the investigator is in an area where the methods and the materials available to him allow the purposeful selection and creation of situations and appropriate comparative controls.. All research starts with a question, and unless the question is clear and can be approached by existing methods, the research is at least premature until applicable methods are developed. The question, or hypothesis, is ...
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How to extract transform and load observational data? Martijn Schuemie Janssen Research & Development Department of Pharmacology & Pharmacy, The University of Hong Kong Outline Observational data & research
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|a href=http://www.nydailynews.com/gossip/bwiddicombe/index.html|Brad Pitt and Angelina Jolie|/a| laughed at a Best Western sign on 49th and Lex. |a href=http://www.nypost.com/seven/10042007/gossip/pagesix/downtown_jen.htm|Jennifer Aniston|/a| bought a condo in the financial-district building that used to house the Chase Manhattan Bank office. Secret Service agents protecting |a href=http://www.nypost.com/seven/10042007/gossip/pagesix/service_glitch.htm|Jenna Bush|/a| while she taped an appearance on |em|The Early Show |/em|mistakenly locked themselves out of their car. Russian billionaire heiress |a href=http://www.nypost.com/seven/10042007/gossip/pagesix/procedure_not_on_tonsils.htm|Anna Anisimova|/a| debuted her new breasts at Russell Simmonss surprise birthday party. |a href=http://www.nypost.com/seven/10042007/gossip/pagesix/rooting_young.htm|In Touch|/a| wanted to run the story, Is Angelina Jolie Pregnant, so they bought up a bunch of pictures of her with a flat stomach so no one else could use
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Retrospective 148 hospitalized patients showing triple therapy with ivermectin + atorvastatin + N-acetylcysteine resulted in a 1.35% case fatality rate which was well below the national average ...
Avis de non-responsabilité: CDA Oasis ne fournit pas de conseils médicaux, de diagnostics ou de traitements. CDA Oasis se veut une source dinformation clinique sommaire qui est facile daccès et non pas une source dinformation exhaustive. Tout auteur qui soumet une opinion ou un fait allégué à la présente publication en assume la responsabilité. Ces opinions et ces faits ne reflètent pas nécessairement la position de lAssociation dentaire canadienne (ADC).. Léditeur se réserve le droit, à son entière discrétion, de : (i) réviser tout texte soumis à CDA Oasis; (ii) ne pas afficher le contenu ou un élément soumis à CDA Oasis; (iii) retirer tout contenu ou élément qui a été affiché dans CDA Oasis.. La publication de toute publicité ne sous-entend pas nécessairement que lADC en approuve les allégations ou quelle les corrobore.. ...
Avis de non-responsabilité: CDA Oasis ne fournit pas de conseils médicaux, de diagnostics ou de traitements. CDA Oasis se veut une source dinformation clinique sommaire qui est facile daccès et non pas une source dinformation exhaustive. Tout auteur qui soumet une opinion ou un fait allégué à la présente publication en assume la responsabilité. Ces opinions et ces faits ne reflètent pas nécessairement la position de lAssociation dentaire canadienne (ADC).. Léditeur se réserve le droit, à son entière discrétion, de : (i) réviser tout texte soumis à CDA Oasis; (ii) ne pas afficher le contenu ou un élément soumis à CDA Oasis; (iii) retirer tout contenu ou élément qui a été affiché dans CDA Oasis.. La publication de toute publicité ne sous-entend pas nécessairement que lADC en approuve les allégations ou quelle les corrobore.. ...
As iodotironinas desiodases formam uma família de selenoenzimas com propriedades catalíticas distintas que ativam ou inativam os hormônios tireoidianos via desiodação do anel fenólico ou tirosínico da molécula do T4. As desiodases tipo I e II (D1 e D2) são as enzimas responsáveis pela geração do T3 e são amplamente expressas na tireóide normal. A transformação neoplásica benigna ou maligna da glândula tireóide está associada a alterações na expressão dessas isoenzimas, sugerindo um possível papel da D1 e da D2 como marcadores de diferenciação celular. Anormalidades na expressão de ambas enzimas e da desiodase tipo III (D3), inativadora do hormônios tireoidianos, são também encontradas em outras neoplasias humanas. Os mecanismos ou implicações do aumento ou diminuição das desiodases na patogênese neoplásica são pouco compreendidas. No entanto, é importante observar que a expressão anormal da D2 pode ser responsável por um quadro de tireotoxicose em ...
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TY - JOUR. T1 - Prospective observations study protocol to investigate cost-effectiveness of various prenatal test strategies after the introduction of noninvasive prenatal testing. AU - Kim, So Yeon. AU - Lee, Seung Mi. AU - Jun, Jong Kwan. AU - Han, You Jung. AU - Kim, Min Hyoung. AU - Shim, Jae Yoon. AU - Lee, Mi Young. AU - Oh, Soo young. AU - Lee, Joon Ho. AU - Kim, Soo Hyun. AU - Cha, Dong Hyun. AU - Cho, Geum Joon. AU - Kwon, Han Sung. AU - Kim, Byoung Jae. AU - Park, Mi Hye. AU - Cho, Hee Young. AU - Ko, Hyun Sun. AU - Ahn, Jeonghoon. AU - Ryu, Hyun Mee. N1 - Publisher Copyright: © 2018 The Author(s). Copyright: Copyright 2019 Elsevier B.V., All rights reserved.. PY - 2018/7/24. Y1 - 2018/7/24. N2 - Background: Among the non-invasive screening methods for the identification of fetal aneuploidy, NIPT (non-invasive prenatal testing) shows the highest sensitivity and specificity in high-risk pregnancies. Due to the low false positive rate of NIPT, it is assumed that the implementation of ...
The effects of a single 3-mg dose of melatonin on the postural control and cognitive performance of community-dwelling older adults were documented. The testing involved stepping down while performing a cognitive task (a Stroop test). Thirty-four older adults were recruited. Immediately before and 1 hr after taking a dose of melatonin, they completed a single-leg standing task after stepping down with and without a simultaneous Stroop test, and a double-leg standing task. The findings indicated a statistically significant increase in sway area under the dual-tasking condition after taking melatonin (p = .04) and the double-leg standing task (p = .018). However, cognitive performance per se was not affected by the melatonin. Melatonin impairs postural control in older adults but not cognitive performance. ...
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Observational research promises to complement experimental research by providing large, diverse populations that would be infeasible for an experiment. Observational research can test its own clinical hypotheses, and observational studies also can contribute to the design of experiments and inform the generalizability of experimental research. Understanding the diversity of populations and the variance in care is one component.
Karim Raza Institute of Inflammation and Ageing, Institute of Inflammation and Ageing, Arthritis Research UK Rheumatoid Arthritis Pathogenesis Centre of Excellence and MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK Biomedical Research Centre, NIHR Birmingham, Birmingham, UK Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK PubMed articlesGoogle scholar articles ...
Downloadable! Meta-regression models are increasingly utilized to integrate empirical results across studies while controlling for the potential threats of data-mining and publication bias. We propose extended meta-regression models and evaluate their performance in identifying genuine em- pirical effects by means of a comprehensive simulation study for various scenarios that are prevalent in empirical economics. We can show that the meta-regression models here pro- posed systematically outperform the prior gold standard of meta-regression analysis of re- gression coefficients. Most meta-regression models are robust to the presence of publication bias, but data-mining bias leads to seriously inflated type I errors and has to be addressed explicitly.
The Mobile Food Vending License is issued to an individual who will prepare and/or serve food from a permitted mobile food vending unit (truck or pushcart). The license is issued by the Department of Health and Mental Hygiene (DOHMH) as a photo ID badge. There are no waiting lists to apply for the Mobile Food Vending License.|br/||br/|
Miguel Marinos research interest lies in population-based studies using large administrative observational data sources and electronic health records. He focuses on development and implementation of novel statistical methodology to address complexities associated with the use of electronic health records to study changes in policy, validation of the electronic reords as a reliable source for observation studies, and design and analysis of cluster-based randomized trials. Marino is also involved in the development of new cardiometabolic risk prediction models for preventive health maintenance and the study of the effect of workplace interventions on sleep and cardiometabolic outcomes. Marino is also the lead biostatistician for the national evaluation of the Agency for Healthcare Research & Quality initiative called EvidenceNOW: Advancing Heart Health in Primary Care.. Along with his research, Marino is interested in mentoring graduate students and teaching statistical principles to ...
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Despite its widespread use in some countries, virtually no scientific authority takes homeopathy seriously. There are several reasons for this intense skepticism, but the most important focuses on a basic fact of chemistry. Simply put, there is nothing material left in a high-potency homeopathic product; some force of nature unknown to modern science would have to be involved for homeopathy to work.. Here is why. In the process of making a 30c homeopathic product, the original substance is diluted by a factor of one part in 1030. This is such an enormous dilution that none of the substance could possibly remain. The so-called highest potency homeopathic products, therefore, contain no active ingredients. Low potency remedies (6s, 12c) do contain a measurable amount of substance, but these remedies are supposedly less effective than the high potency forms. It goes against basic chemistry principles that a solution with no product is stronger than a solution with a small amount of the product. ...
Three publications were selected based on the strength of the research questions, but also because they represent different research designs that are used with varying degrees of frequency in the pediatric literature. The first, a prospective, longitudinal cohort observation study from 7 to 16 years with girls and boys reports an intrinsic reduction in absolute resting energy expenditure after adjustment for lean mass, fat mass, and biological maturity. The authors suggest this could be related to evolutionary energy conservation, but may be problematic now that food energy availability is so abundant. The second focuses on the effect of acute exercise on neutrophil reactive oxygen species production and inflammatory markers in independent groups of healthy boys and men. The authors suggested the boys experienced a sensitized neutrophil response stimulated by the exercise bout compared with the men; moreover, the findings provided information necessary to design future trials in this important ...
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Abc s du foie. M tronidazole, 750 mg x 3 / j pendant 5 10 jours ou 2.4 g/j pendant 1 2 jours. Plus diloxanide ou paromomycine ou, si le m tronidazole n est pas tol r D hydro m tine 1 1.5 mg/Kg/j pendant 5 jours plus diloxanide ou paromomycine. Porteurs asymptomatiques. Furoate de diloxanide, 500 mg x 3 / j pendant 10 jours, ou. Paromomycine 30 mg/Kg/j en 3 prises pendant 5 10 jours, ou. T tracycline 250 mg x 4/j pendant 10 jours, puis diiodohydroxyquinol ine, 650 mg x 3/j pendant 20 jours. Rectocolite invasive. M tronidazole 750 mg x 3 / jour pendant 5 10 jours. ou 2.4 grammes / jour pendant 2 3 jours. plus diloxanide ou paromomycine ou, si le m tronidazole n est pas tol r D hydro m tine 1 1.5 mg/Kg/j pendant 5 jours plus diloxanide ou paromomycine. ...
Applications to access CPRD data for observational research are reviewed by the Independent Scientific Advisory Committee (ISAC). Approval by ISAC is required for researchers to carry out their proposed studies.. A summary of all ISAC-approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication.. The table below includes all ISAC-approved protocols submitted to CPRD from 1st July 2015. Protocols below are listed in order of date of approval. Please click on the study title for more details.. Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. ...
Applications to access CPRD data for observational research are reviewed by the Independent Scientific Advisory Committee (ISAC). Approval by ISAC is required for researchers to carry out their proposed studies.. A summary of all ISAC-approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study.. The table below includes all ISAC-approved protocols submitted to CPRD from 1st July 2015. Searches can be carried out using applicant names, approval date or by using key words within the protocol title. Protocols below are listed in order of date of approval.. Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. ...
Individuals with coronavirus disease 2019 (COVID-19) can develop pneumonia and a severe inflammatory response with excessive cytokine release known as the cytokine storm. The JAK inhibitor baricitinib, used to treat rheumatoid arthritis, reduces inflammation by modifying the cytokine pathway. In this issue of the JCI, Bronte, Ugel, and colleagues performed an observational longitudinal study to evaluate the use of baricitinib in 20 patients with COVID-19. The treated patients showed reduced levels of plasma IL-6, TNF, IL-1β, and phosphorylated STAT3 as well as swift lymphocyte restoration. Notably, these patients had a dramatically favorable clinical outcome. While bias can plague uncontrolled research, this study has biological credibility and warrants randomized, controlled studies.. ...
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Background Multiple Sclerosis (MS) is the most common cause of neurological disability in young and middle-aged adults. At this stage in life most people are in the midst of their working career. The...
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A relação de emprego, ou o vínculo empregatício, é um fato jurídico que se configura quando alguém (empregado ou empregada) presta serviço a uma outra pessoa, física ou (empregador ou empregadora), de forma subordinada, pessoal, não-eventual e onerosa. Essa relação geralmente é baseada num contrato em que uma das partes é o empregado remunerado pela outra parte, que é a empregadora, podendo ser uma corporação com fins lucrativos, organização sem fins lucrativos, cooperativas ou qualquer outra entidade que empregue um indivíduo. Ter um emprego, não só constitui o principal recurso com que conta a maioria das pessoas para suprir as suas necessidades materiais, como também lhes permite plena integração social. Por isso, a maior parte dospaíses reconhece o direito ao trabalho como um dos direitos fundamentais dos cidadãos.Emprego é a função e a condição das pessoas que trabalham, em caráter temporário ou permanente, em qualquer tipo de atividade econômica, ...
La pr sente invention concerne un micro- l ment mobile effet dimpression ou dhyst r se r duit plac une certaine distance dune surface comprenant au moins une lectrode. Au moins un l ment de restauration est connect ce micro- l ment mobile. Une lectrode adresse, plac e sur cette surface, est capable dexercer une attirance lectro-statique sur ce micro- l ment mobile. Cette lectrode adresse est adress e un premier potentiel. Ce micro- l ment mobile est dabord r gl un deuxi me potentiel d finissant un tat non adress et, un temps Δt avant quun signal puls pr d termin ne soit mis, ce micro- l ment mobile est commut du deuxi me potentiel un troisi me potentiel qui d finit un tat adress . Ce micro- l ment mobile est gard dans cet tat adress pendant un temps Δt+Δt. Linvention concerne galement un modulateur spatial de lumi re (SLM), un appareil de formation des motifs dune pi ce et un proc d permettant de r duire un effet dimpression ou dhyst r se dun micro- l
No ambiente jurídico chamamos de tese uma teoria ou argumento jurídico segundo o qual o entendimento do fisco ou a aplicação de determinada lei contraria um direito do contribuinte. Munidos destas teses os contribuintes buscam no judiciário reduzir sua carga tributária e/ou reembolsar-se de pagamentos a maior efetivados nos últimos cinco anos.. Como enxergar uma tese tributária do ponto de vista do empresário:. Atuando em conselhos e comitês de empresas imbuídos muitas vezes da atribuição de decidir ou recomendar a adesão ou não da empresa a alguma tese tributária, aprendi que para além de critérios técnicos ou subjetivos, como a opinião do advogado sobre a probabilidade de êxito de determinada tese, é preciso analisar os riscos e oportunidades objetivos relacionados a cada qual.. Em outras palavras, como diria um empresário com quem trabalhamos, é preciso transformar o juridiquês em números. Neste sentido padronizamos alguns critérios de custo e benefício a serem ...
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Objectif : Étudier lactivité anti-tumorale dun régime de chimiothérapie métronomique à 4 médicaments dans les tumeurs solides extra-crâniennes récurrentes et/ou progressives de lenfant. Lobjectif principal était la survie sans progression après 2 cycles de traitement. Méthodes : Les patients âgés de 4 à 25 ans avec une tumeur solide extra-crânienne progressive et dont la fonction de lorgane était adéquate étaient éligibles. Le traitement consistait en cycle de chimiothérapie de 8 semaines associant du célécoxib par voie orale, de la vinblastine intraveineuse hebdomadaire et du cyclophosphamide pendant 3 semaines en alternance avec du méthotrexate oral pendant 3 semaines, avec 2 semaines de repos. Le modèle en deux étapes Kepner-Chang a été utilisé avec linclusion de 10 patients à la première étape. Lorsque lobjectif principal était atteint chez 2 patients ou plus, 8 patients supplémentaires ont été inclus selon 4 groupes : Neuroblastome, sarcome des tissus
Pour tout achat entre le 21/10/2014 et le 21/02/2015 dun Blu-Ray ou DVD X-Men: Days of Future Past, b n ficie dun remboursement de 3 ou 5 avec la Carte Moza c M6 du Cr dit Agricole ...
Clinical Trials - clinicaltrials.gov This is a multicentre observational study which involves 43 of the major Italian centres that treat MS. The duration expect...
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Pou f istwa f k ou GNB. Depi ou nan sa z t pral di, oubyen sa z t ap di, ou timoun toujou. Nan lavi, yon nonm pa gen karakt san bon konviksyon. Depi ou fin f istwa, se met grenn nan d y ou pou pote chay tout sa ki vin av k li. Rezon Richard bay yo ki f li pa ta renmen patisipe nan yon l t pwoj konsa ank , manke pwa, yo f anfanten. S l si Richard gen l t ti bagay li pa vle di nou.... Vr rezon ki f li pa ta renmen enplike nan yon l t pwoj konsa ank ? K m paw l ti n g pa janm piti, se janm kanson l s lman ki piti. Kidonk, nou pa konnen ...
Pou f istwa f k ou GNB. Depi ou nan sa z t pral di, oubyen sa z t ap di, ou timoun toujou. Nan lavi, yon nonm pa gen karakt san bon konviksyon. Depi ou fin f istwa, se met grenn nan d y ou pou pote chay tout sa ki vin av k li. Rezon Richard bay yo ki f li pa ta renmen patisipe nan yon l t pwoj konsa ank , manke pwa, yo f anfanten. S l si Richard gen l t ti bagay li pa vle di nou.... Vr rezon ki f li pa ta renmen enplike nan yon l t pwoj konsa ank ? K m paw l ti n g pa janm piti, se janm kanson l s lman ki piti. Kidonk, nou pa konnen ...
La pr sente invention concerne un proc d et un dispositif permettant de r guler la temp rature dun patient et, en particulier, dinduire une hypothermie th rapeutique. Sont d crits divers modes de r alisation. Le syst me comprend : une source de gaz respirer pouvant se pr senter sous la forme dun m lange de gaz respirer comprim ; un changeur de chaleur ou autre dispositif de chauffage et/ou de refroidissement ; et une interface de respiration telle quun masque respiratoire ou un tube endotrach al. Le syst me peut ventuellement tre assorti de divers dispositifs tels que respirateur m canique, n bulisateur pour introduction de m dicaments dans le gaz respirer, dune sonde thermom trique pour le corps et une unit de commande r action. Pour augmenter le transfert thermique, on peut utiliser avec ce syst me de lair ou un m lange respirer sp cial tel que He/02 ou SF6/02. De plus, le syst me peut inclure un g n rateur de particules de glace qui, introduites dans le flux du gaz respirer,
Avis de non-responsabilité: CDA Oasis ne fournit pas de conseils médicaux, de diagnostics ou de traitements. CDA Oasis se veut une source dinformation clinique sommaire qui est facile daccès et non pas une source dinformation exhaustive. Tout auteur qui soumet une opinion ou un fait allégué à la présente publication en assume la responsabilité. Ces opinions et ces faits ne reflètent pas nécessairement la position de lAssociation dentaire canadienne (ADC).. Léditeur se réserve le droit, à son entière discrétion, de : (i) réviser tout texte soumis à CDA Oasis; (ii) ne pas afficher le contenu ou un élément soumis à CDA Oasis; (iii) retirer tout contenu ou élément qui a été affiché dans CDA Oasis.. La publication de toute publicité ne sous-entend pas nécessairement que lADC en approuve les allégations ou quelle les corrobore.. ...
Numéro didentification: WO/2020/ (lien OMPI) Numéro didentification CEA : BD18267 Année de dépôt : 15-11-2018 Date de publication : 20-05-2020 Pour le domaine cosmétique, pigments cosmétiques omniphobes sous la forme dune structure noyau-enveloppe : le noyau est ou comprend un oxyde métallique sur lequel sont adsorbées des chaînes de poly(β-(1→4)-D-glucosamine) ; les chaînes étant acétylées, ou partiellement ou totalement désacétylées. De même, le procédé de fabrication des pigments cosmétiques omniphobes, y compris : (i) la préparation dune solution aqueuse acide comprenant des particules doxyde métallique et une poly (β-(1→4)-D-glucosamine), la poly (β-(1→4)-D-glucosamine) étant acétylée ou partiellement ou totalement désacétylée ; et (ii) laugmentation du pH jusquà 12, de la solution obtenue à létape (i) afin dobtenir ladsorption de ladite poly (β-(1→4)-D-glucosamine sur les particules doxyde métallique et la
A causa mais comum de mortalidade no paciente diab tico a doen a cardiovascular, tendo como um de seus principais representantes a doen a arterial coronariana (DAC). Homens acima de 40 anos e mulheres acima de 50 anos com DM tipo um ou tipo dois, geralmente, apresentam risco de eventos coronarianos > 2% ao ano. O risco de eventos cardiovasculares ou bito ser mais elevado quando houver diagn stico cl nico de DAC cr nica ap s infarto do mioc rdio, acidente vascular cerebral (AVC) ou ataque isqu mico transit rio ou mesmo na presen a de angina do peito, dispneia de origem isqu mica (equivalente anginoso), claudica o intermitente ou doen a da aorta. Os objetivos fundamentais do tratamento da DAC cr nica nos pacientes diab ticos n o se diferenciam da popula o n o diab tica e incluem: preven o do infarto do mioc rdio e redu o da mortalidade; redu o dos sintomas e da ocorr ncia da isquemia mioc rdica, proporcionando melhor qualidade de vida. Todos os pacientes diab ticos com doen a cardiovascular ...
En bioloxía molecular e xenética, o contido GC, contido guanina-citosina, porcentaxe GC ou contido G+C (ás veces razón GC) é a porcentaxe de bases nitroxenadas dunha molécula de ADN que son guanina ou citosina de entre o total das catro baes posibles (adenina, timina, guanina e citosina). O contido GC pode referirse a un determinado fragmento de ADN, a un cromosoma completo ou a un xenoma enteiro. Pode aplicarse tamén ao ARN (que tería uracilo en vez de timina). Cando se refire a un fragmento do material xenético este pode ser unha parte dun xene (dominio), un só xene completo, un grupo de xenes (ou cluster), ou mesmo a unha rexión non codificante. Nas medicións en xenomas bacterianos o normal é expresalo en %mol. A guanina (G) e a citosina (C) emparéllanse no ADN formando 3 enlaces de hidróxeno, mentres que a timina (T) e a adenina (A) únense entre si por medio de dous destes enlaces. O ADN cun alto contido GC é máis estable que o de contido baixo porque forman máis pontes de ...
6. Composition photosensible selon la revendication 5, caract ris e en ce que le polym re contenant des groupes hydroxy ou amino est un polym re contenant des motifs alcool vinylique, alcool allylique, acrylate dhydroxyalkyle ou m thacrylate dhydroxyalkyle, une r sine poxy, un ther de cellulose, un ester de cellulose ou un polyester comportant des groupes hydroxy libres, ou une polyamine, un polyamide ou un polyur thanne ...
Lainey Gossip|Cameron Diaz updates including latest news, photos, video, opinions, commentary, style, career, roles, movies, awards, relationships
Answers to your questions about Nelson W. Wards life, age, relationships, sexual orientation, drug usage, net worth and the latest gossip!
Soap fans love a good piece of drama … why else would anyone tune in daily and weekly, right? For many viewers that hour (or hours) in the afternoon can be a
Dec 21, 2017 0 Yesterday (Dec 18) was a day of mourning for K-pop fans worldwide. The lead singer of SHINee, Kim Jong Hyun, had unfortunately passed away. Must See- Padmavati - Unknown Facts His elder sister made a police report to 4.42pm KST claiming that her brother might be committing suicide, as ...
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Blind Gossip] Weve received tons of inquiries today from people wanting to know the REAL reason behind the divorce of this prominent Actor and Actress.. There are actually several reasons. Just put aside the accusations all that are flying around (You cheated! You are a bad role model for the kids! Youre crazy!) for a minute, while we tell you about the big straw that broke the camels back.. The Other Woman is pregnant. The Actor might be the father.. Similar: Buns And Twists. Actor:. Actress:. The Other Woman:. [Optional] Do you think The Actor is the father?. ...
Kim Zolciak and husband Kroy Biermann arrived at LAX to fly back to Atlanta, and while they were going to security, the couple obliged the paparazzi in a gossip session ...