TY - JOUR. T1 - Effect of Vagal Nerve Blockade on Moderate Obesity with an Obesity-Related Comorbid Condition. T2 - the ReCharge Study. AU - Morton, John M.. AU - Shah, Sajani N.. AU - Wolfe, Bruce. AU - Apovian, Caroline M.. AU - Miller, Christopher J.. AU - Tweden, Katherine S.. AU - Billington, Charles J.. AU - Shikora, Scott A.. PY - 2016/5/1. Y1 - 2016/5/1. N2 - Background: Vagal nerve blockade (vBloc) therapy was shown to be a safe and effective treatment for moderate to severe obesity. This report summarizes the safety and efficacy of vBloc therapy in the prespecified subgroup of patients with moderate obesity. Methods: The ReCharge Trial is a double-blind, randomized controlled clinical trial of participants with body mass index (BMI) of 40-45 or 35-40 kg/m2 with at least one obesity-related comorbid condition. Participants were randomized 2:1 to implantation with either a vBloc or sham device with weight management counseling. Eighty-four subjects had moderate obesity (BMI 35-40 kg/m2) ...
How Obesity Leads To Diabetes Mellitus is a thoughtful condition. Learn about How Obesity Leads To Diabetes Mellitus or are you at risk for How Obesity Leads To Diabetes
How can we solve the problem of obesity-related diseases when many doctors have trouble diagnosing them? Dr. Mark Hyman sits down to talk about his new book, The Blood Sugar Solution.
Without action on obesity, the economic burden of treating obesity-related diseases is estimated to rise from $12 billion in 2014 to $21 billion in 2025.
This article is a report on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at the Experimental Biology 12 meeting in San Diego, CA. The presentations discussed the roles of a number of nuclear receptors in regulating glucose and lipid homeostasis, the pathophysiology of obesity-related disease states, and the promise associated with targeting their activities to treat these diseases. While many of these receptors (in particular, constitutive androstane receptor and pregnane X receptor) and their target enzymes have been thought of as regulators of drug and xenobiotic metabolism, this symposium highlighted the advances made in our understanding of the endogenous functions of these receptors. Similarly, as we gain a better understanding of the mechanisms underlying bile acid signaling pathways in the regulation of body weight and glucose homeostasis, we see the importance of using complementary approaches to elucidate this fascinating network ...
Overview. The mathematical sciences including engineering, statistics, computer science, physics, econometrics, psychometrics, epidemiology, and mathematics qua mathematics are increasingly being applied to advance our understanding of the causes, consequences, and alleviation of obesity. These applications do not merely involve routine well-established approaches easily implemented in widely available commercial software. Rather, they increasingly involve computationally demanding tasks, use and in some cases development of novel analytic methods and software, new derivations, computer simulations, and unprecedented interdigitation of two or more existing techniques. Such advances at the interface of the mathematical sciences and obesity research require bilateral training and exposure for investigators in both disciplines. This course on the mathematical sciences in obesity research features some of the worlds finest scientists working in this domain to fill this unmet need by providing nine ...
Obesity 2011, the 29th Annual Scientific Meeting of The Obesity Society, is less than 1 month away!. Mark your calendars! Please join us on Tuesday, October 4 from 12:15-2:15pm for the annual Pediatric Obesity Section Meeting and Bar-Or Lecture. It is our pleasure to announce Dr. Nancy Butte as the 2011 recipient of the Oded Bar-Or Award for Excellence in Pediatric Obesity Research. Founded in 2007 by Dr. Melinda Sothern and Dr. Michael Goran, the Bar-Or Award raises public awareness of pediatric obesity research efforts by formally recognizing significant lifetime contributions of leaders in the field. Dr. Butte, Professor of Pediatrics at Baylor College of Medicine, is an internationally recognized expert in human nutrition and metabolism with a focus on childhood obesity. Dr. Anthony Comuzzie, Scientist at the Texas Biomedical Research Institute and colleague of Dr. Buttes, will make the formal presentation of the award, which will be followed by an address by Dr. Butte. The Bar-Or Lecture ...
Background: Extreme obesity (BMI ≥ 40 kg/m2) is becoming more prevalent in the United States. Little is known about the outcomes of percutaneous coronary intervention (PCI) in this subgroup. We compared the in-hospital outcomes of PCI in this subgroup with that of the normal weight patients in the CathPCI Registry®.. Methods: All extremely obese patients who had undergone PCI procedures between Feb 28, 2008 and Jun 30, 2011 via the femoral or radial artery (N= 83,861) were compared with those of normal weight patients (BMI 20-25 kg/m2, N= 217,616) in the NCDR. Outcomes included in-hospital mortality, procedural and bleeding complications. Multivariable logistic regression models were used to assess the independent association of extreme obesity with outcomes, using previously validated risk models derived from NCDR.. Results: Compared with normal weight patients, extremely obese patients had a lower median age (60 vs. 69 years old), were more likely to be female (47% vs. 37%), and African ...
How obesity leads to diabetes - Monash University researchers have found how obesity leads to type 2 diabetes - a finding that could lead to the design of a drug to prevent the disease. - AndhraNews.net
Several studies have shown that normal weight central obesity (NWCO) is associated with cardiovascular disease (CVD) risk factors. However, studies conducted in the Japanese population have been very limited. Thus, the relationships between normal weight central obesity, classified using body mass index (BMI), the waist-to-height ratio (WHtR), and CVD risk factors in middle-aged Japanese adults were investigated. The participants were Japanese adults aged 40-64 years who had undergone periodic health examinations in Japan during the period from April 2013 to March 2014. The participants were categorized into the following four groups: normal weight (BMI 18.5-24.9 kg/m2) and no central obesity (WHtR | 0.5) (NW); normal weight and central obesity (WHtR ≥ 0.5) (NWCO); obesity (BMI ≥ 25 kg/m2) and no central obesity (OB); and obesity and central obesity (OBCO). Hypertension was defined as systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, or taking medication for hypertension.
Several studies have shown that normal weight central obesity (NWCO) is associated with cardiovascular disease (CVD) risk factors. However, studies conducted in the Japanese population have been very limited. Thus, the relationships between normal weight central obesity, classified using body mass index (BMI), the waist-to-height ratio (WHtR), and CVD risk factors in middle-aged Japanese adults were investigated. The participants were Japanese adults aged 40-64 years who had undergone periodic health examinations in Japan during the period from April 2013 to March 2014. The participants were categorized into the following four groups: normal weight (BMI 18.5-24.9 kg/m2) and no central obesity (WHtR | 0.5) (NW); normal weight and central obesity (WHtR ≥ 0.5) (NWCO); obesity (BMI ≥ 25 kg/m2) and no central obesity (OB); and obesity and central obesity (OBCO). Hypertension was defined as systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, or taking medication for hypertension.
The Danish court, where the obesity disability case was filed, asked the EU Court to decided whether obesity is a basis on which workers could claim disability. The court in Denmark will be tasked to determine if the instance of the fired childminder is one in which his obesity can be classified as a disability.. While the ruling does declare that some cases of obesity can be considered disability, the Guardian reports that it stops short, however of declaring obesity to be a protected characteristic again which all discrimination is prohibited. In doing so, the court did not classify all instances of obesity as a disability. Karsten Kaltoff, the fired childminder, claims his obesity is not a disability, and claims he can perform the duties of the job from which he was fired. He doesnt see himself as disabled, and doesnt believe he should have been fired due to his obesity. ...
The World Health Organization has called childhood obesity one of the most serious public health challenges of the 21st century. The alarming childhood obesity epidemic brings with it increasing need for pediatricians to treat obesity-related diseases (e.g., type II diabetes mellitus, hypertension, hyperlipidemia, gastroesophageal reflux disease [GERD]) that traditionally have not had origins in childhood or adolescence, leading to a critical therapeutic information gap in pediatrics. Given that obese participants are often excluded from clinical trials during the drug development process, little to no information exists regarding the impact of obesity on drug disposition and action or the appropriate dosing of drugs in obese pediatric patients.. Obese children are more frequently diagnosed with GERD than children of normal weight. Proton pump inhibitors, such as pantoprazole, have become key components in the pharmacological management of GERD in pediatrics. In this multicenter, open-label, ...
Childhood overweight and obesity (ow/ob) has become a serious threat to many countries, including China. However, limited evidence was obtained from longitudinal data in China. This study examined the secular trends and geographic variation in the prevalence of ow/ob and obesity only, and age, gender, and urban-rural disparities among school-aged children across China. Data from children aged 6-17 surveyed in China Health and Nutrition Survey (CHNS) from 1991 (n = 2712) to 2011 (n = 1054) were used. Overweight and obesity were defined based on the International Obesity Task Force (IOTF) recommended Asian age-sex-specific BMI cut-off-points. We found that: (1) childhood ow/ob and obesity prevalence increased from 11.7% to 25.2% and from 2.8% to 10.1% during 1991-2011, respectively; (2) children aged 6-12 experienced a 1.3 and 1.6 times increase in ow/ob and obesity prevalence than children aged 13-17, respectively; (3) the urban-rural gap in ow/ob prevalence widened; (4) ow/ob prevalence in boys was
Michael Corsilles, ND, PA-C. Obesity may be the number one antiaging issue in our society simply because it shortens our life span. Children are developing serious diseases at a younger age, which prematurely subjects them to the deterioration of their health and bodies. Diabetes mellitus, asthma, hypertension, sleep apnea, and cancer are just a few examples.1 Obesity also has an emotional influence that can affect self-image and self-confidence, leading to depression and poor food choices, such as comfort foods. Societal pressures take a toll on individuals, spanning generations. In addition, obesity is not a local trend; it is a worldwide epidemic and is occurring in younger patients, even toddler age.2 Fortunately, our country is tackling the obesity problem head on. In February of last year, First Lady Michelle Obama launched the Lets Move! campaign to solve the childhood obesity epidemic, and President Barack Obama established the White House Task Force on Childhood Obesity to implement ...
The risk of obesity in adulthood is subject to programming beginning at conception. In animal models, exposure to maternal obesity and high fat diets influences the risk of obesity in the offspring. Among other long-term changes, offspring from obese rats develop hyperinsulinemia, hepatic steatosis, and lipogenic gene expression in the liver at weaning. However, the precise underlying mechanisms leading to metabolic dysregulation in the offspring remains unclear. Using a rat model of overfeeding-induced obesity, we previously demonstrated that exposure to maternal obesity from pre-conception to birth, is sufficient to program increased obesity risk in the offspring. Offspring of obese rat dams gain greater body weight and fat mass when fed high fat diet (HFD) as compared to lean dam. Since, disruptions of diurnal circadian rhythm are known to detrimentally impact metabolically active tissues such as liver, we examined the hypothesis that maternal obesity leads to perturbations of core clock components
The diet-induced obesity model (DIO model) is an animal model used to study obesity using animals that have obesity caused by being fed high-fat and/or high-density diets. It is intended to mimic the most common cause of obesity in humans. Typically mice, rats, dogs, or non-human primates are used in these models. These animals can then be used to study in vivo obesity, obesitys comorbidities, and other related diseases. Users of such models must take into account the duration and type of diet (e.g. hydrated gels vs. dry pellets) as well as the environmental conditions and age of the animals, as each may promote different bodyweights, fat percentages, or behaviors. Driven by the worldwide epidemic of obesity, particularly in the Western world, the DIO model has been integral in understanding the relationship between high-fat/high-density diets and obesity, including the discovery of Akt and mTOR, signals in the body linked to obesity and insulin resistance. However, while many insights into the ...
TY - JOUR. T1 - Mouse model implicates GNB3 duplication in a childhood obesity syndrome. AU - Goldlust, Ian S.. AU - Hermetz, Karen E.. AU - Catalano, Lisa M.. AU - Barfield, Richard T.. AU - Cozad, Rebecca. AU - Wynn, Grace. AU - Ozdemir, Alev Cagla. AU - Conneely, Karen N.. AU - Mulle, Jennifer G.. AU - Dharamrup, Shikha. AU - Hegde, Madhuri R.. AU - Kim, Katherine H.. AU - Angle, Brad. AU - Colley, Alison. AU - Webb, Amy E.. AU - Thorland, Erik C.. AU - Ellison, Jay W.. AU - Rosenfeld, Jill A.. AU - Ballif, Blake C.. AU - Shaffer, Lisa G.. AU - Demmer, Laurie A.. AU - Searle, Beverly A.. AU - Wynn, Sarah L.. AU - Rudd, M. Katharine. PY - 2013/9/10. Y1 - 2013/9/10. N2 - Obesity is a highly heritable condition and a risk factor for other diseases, including type 2 diabetes, cardiovascular disease, hypertension, and cancer. Recently, genomic copy number variation (CNV) has been implicated in cases of early onset obesity that may be comorbid with intellectual disability. Here, we describe a ...
The BDA Obesity specialist group represents dietitians working in adult and childhood obesity prevention and management, recognising obesity as being a specialist area of dietetic practice. The Obesity specialist group works to communicate evidence-based standards, support post-registration training in obesity management, contribute to national guidelines, campaign for health improvement, and to develop and foster a network of obesity management professionals.. Any BDA member can become a member of the Obesity specialist group. Members are kept up-to-date via regular newsletters and emails. Members are also encouraged to join our LinkedIn network to have the opportunity to contribute to national consultations and other ongoing projects. There is also the potential to make a more direct impact via volunteering for active committee positions. Members can also benefit from discounted rates for study days and grants to support obesity research, evaluation or audit . ...
Quite a few individuals may be aware that obesity elevates risk of cardiovascular disease and diabetes. Experts from the Medical College of Georgia claim
Despite a strong association between body weight and mortality in the general population, clinical evidence suggests better clinical outcome of overweight or obese individuals with established coronary heart disease. This finding has been termed the obesity paradox, but its existence remains a point of debate, because it is mostly observed when body mass index (BMI) is used to define obesity. Inherent limitations of BMI as an index of adiposity, as well as methodological biases and the presence of confounding factors, may account for the observed findings of clinical studies. In this review, our aim is to present the data that support the presence of a BMI paradox in coronary heart disease and then explore whether next to a BMI paradox a true obesity paradox exists as well. We conclude by attempting to link the obesity paradox notion to available translational research data supporting a healthy, protective adipose tissue phenotype. © 2016 World Obesity.
Understanding Obesity informs readers about contributing factors to obesity: from social and behavioral determinants throughout the life course, influences from before we are born to what we eat (nutrients and food contaminants which impact body weight), gut bacteria, and the way accumulated energy from nutrition is spent. Chapters will also inform readers about adipose tissue (the dynamic role of the adipose tissue during obesity development, the pressure put on to its remodeling and differences in obesity phenotypes regarding association with pathological outcomes as well as the latest advances in finding biological markers of adipose tissue dysfunction) and the latest treatment options for obesity. Special topics, such as the bidirectional relationship of stress with obesity and the influence of aging on the onset of metabolic disorders that lead to obesity are also discussed. Understanding Obesity is a valuable reference for health researchers, practitioners (endocrinologists, family ...
Little is known concerning obesity patterns of ethnic subpopulations in the U.S. and the effects of acculturation on these patterns. Adolescent obesity, a major public health problem, has important health, social and economic consequences for the adolescent. The National Longitudinal Study of Adolescent Health survey is unique in the size of the adolescent sample and in its ability to provide large representative samples of Anglo, African-American, Hispanic and Asian-American adolescents. A nationally representative sample of 13,783 adolescents was studied. Measurements of weight and height collected in the second wave of the survey were used to study adolescent obesity. Multivariate logit techniques were used to provide an understanding of the ethnic, age, gender and intergenerational patterns of adolescent obesity. Comparisons are presented between the NHANES III results and those from the Adolescent Health Survey. The smoothed version of the NHANES I 85th percentile cut-off was used for the ...
Washington, DC) - Trust for Americas Health (TFAH) commends the Childhood Obesity Task Forces report, Solving the Problem of Childhood Obesity Within a Generation, which includes proposed recommendations for reducing the rate of childhood obesity from 17% to 5% by 2030. The report includes a total of 70 recommendations for specific action steps, many of which can be implemented right away and are minimal or no-cost.. By looking across both the private and public sector and various government entities, these recommendations articulate a comprehensive approach to combating childhood obesity, said Jeffrey Levi, PhD, Executive Director of Trust for Americas Health. The Childhood Obesity Task Force should be commended for setting such specific goals that will help direct the action needed to address this national epidemic.. Levi continued, However, it is now the responsibility of the Administration and Congress to ensure that sufficient resources are provided so that each recommendation can ...
The federal government should encourage healthy habits, including dairy consumption, as part of its fight against childhood obesity, IDFA said in comments submitted to an interagency task force last Friday. IDFA stressed the significant nutritional benefits of dairy products and highlighted the steps processors are taking, such as reformulating products with less sugar, lower calories and reduced fat, to provide a variety of options.. The Task Force on Childhood Obesity was established by President Obama in February, in conjunction with Michelle Obamas public awareness initiative, Lets Move. Charged with developing a national plan to end childhood obesity within a generation, the task force last month issued a call for recommendations from industry and the public. The deadline for comments was March 26.. IDFA supports the administrations focus on childhood obesity and its comprehensive, cross-sector approach that includes a variety of stakeholders, including federal agencies, state and ...
We cannot separate the direct effects of maternal obesity on the developing child from shared genetic and postnatal lifestyle influences in childhood and adulthood on obesity and cardiovascular risk. For example, there is evidence that obesity, unhealthy diets, and lack of exercise cluster in families.23 24 Regarding socioeconomic status, we were able to adjust for current socioeconomic status in a small subset of the adult offspring, though the limited sample size reduced study power and abolished significance. With offspring obesity, it is well recognised that there is a link between socioeconomic status and other adult lifestyle variables including obesity. While some studies have shown that the influence of maternal obesity on offspring obesity is independent of adult lifestyle factors,7 two studies showing associations between maternal obesity and cardiovascular risk factors had attenuated results after adjustment for current obesity levels.9 10 As obesity in offspring is closely correlated ...
Endothelial cell dysfunction, characterised by a reduction in the bioavailability of nitric oxide (NO), plays an important role in the initiation of atherosclerosis. IGF-1 may be involved in the regulation of NO production via the Phosphoinositide 3-kinase (PI3-K)/Akt/eNOS pathway. In this study we have investigated whether dietary-induced obesity leads to disturbances of this pathway. C57/Blk6 mice fed a high fat diet for 20weeks (n=12) showed a significant increase in body weight and fat pad size when compared to chow fed controls (n=12). Blood pressure measurement showed an age-related increase in systolic blood pressure in high fat fed (19.2% from baseline) versus chow fed mice (7.6% from baseline). Blood glucose levels increased from 13.5 to 20mmol/l at 120mins in high fat fed mice, versus 5.7 to 7.3mmol/l in the chow fed group (p=0.009) by tolerance testing. In response to insulin, blood glucose fell by 72% in the chow fed group versus 48% in the high fat fed group (p= 0.0002). The high ...
Van Jaarsveld and Guilford report the results of their study on childhood obesity trends in England from 1994 to 2013 using primary care electronic healthcare records.1 There is undoubtedly some good news: the year on year rise in obesity levels seen in the first decade of data collection was extremely worrying when the odds of overweight or obesity increased by 8% yearly from 1994 to 2003. In the second decade up to 2013, this astounding increase had slowed to 0.4%. However, in this second decade, it remains extremely concerning that adolescent obesity (ages 11-15 years) appears to still be increasing in both boys and girls. The relative risk of remaining obese as an adult if obese in adolescence is very high,2 and the authors rightly point out that with a third of UK children being overweight or obese, the impact on public health remains a key public health priority.. In general, the data from this study broadly agree with the latest Health Survey for England, although the levels of obesity ...
Most studies have focused on the role of breastfeeding versus formula feeding (7,8) as well as of an early rapid weight gain in favouring obesity development (9).. Few studies, however, have focused on the role of complementary feeding (CF) in promoting long term health or favouring the development of obesity, even though CF represents the main source of calories and nutrients already by the end of the first year of life.. One of the commonest reasons given as an explanation for the lack of research on the long-term effects of CF is the huge difference among countries on the foods used during the CF period and the great importance of the cultural roots on weaning patterns.. However, if nutrients and calories are considered instead of foods, the differences among countries on the different CF patterns are much reduced.. Researches aiming at demonstrating the link between an unhealthy CF and the development of later obesity face several challenges such as the lack of randomized trials in human ...
There were 54 patients with diabetes type 2 and 36 non-diabetic. Individuals of two groups of obese and non-obese compared with apparently healthy control. Before the body mass index (kg/m2) had been calculated, weight (kg) and height (m) were measured as a normal weight (18.49-24.99 kg/m2), or obese (, 30kg/m2) according to the WHO classification. Adipolin significantly decreased in obese diabetic patients compared with obese controls and it is low in the obese diabetic patients group compared to the nonobese patients group. TAC was significantly increased in the patients compared with controls (p , 0.05) and it was low level in obese diabetic patients compared with nonobese patients group, while MAD was high level in obese diabetic patients compared with nonobese patients group. The study also found weak negative correlated with MDA (r=-0.29, p= 0.13), TAC (r=-0.023, p=0.9), in obese diabetic patients while found weak positive correlated with MDA (r=0.037, p=0.85), TAC (r=0.35, p=0.69) in ...
Evaluating promising strategies for obesity prevention and treatment in real-world settings and diverse populations is 1 of several research opportunities outlined in the National Institutes of Healths (NIH) new strategic plan for obesity research. Released last week, the plan will serve as a guide to accelerate a broad spectrum of research toward developing new and more effective approaches to address the burden of obesity. Other major themes of research include designing and testing new interventions for achieving and maintaining a healthy weight and harnessing technology and tools to advance obesity research and improve health care delivery. Clinicians can download a full version of the plan; a non-technical summary is available for other audiences. The Strategic Plan for NIH Obesity Research was developed by the NIH Obesity Research Task Force with input from researchers external to the NIH, professional and other health-focused organizations, and others through a public comment period. ...
Obesity is a disease characterized by excessive body fat. It can be caused by environment, a persons early-life nutrition, and it can even be a result of their parents diet. Obesity is so dangerous because associated with many diseases such as hypertension, type-2 Diabetes, cardiovascular disease, and cancer. How does extra weight cause so many different problems? Many studies…
If you snore loudly, become excessively tired, or wake up suddenly and feel short of breath, you may have sleep apnea. Learn how obesity affects sleep.
Health,With the increase in adult obesity rates in 31 states during the past ... All this has happened in spite of federal and state government effo... The report titled F as in Fat: How Obesity Policies Are Failing Am... Official figures show that the adult obesity rate rose from 15 perc... Jeff Levi executive director of Trust for Americas Health said ...,Rise,in,Obesity,Rates,in,31,States,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Identifying actionable links in the causal pathway between obesity and insulin resistance remains a significant challenge in diabetes research. Potentially groundbreaking work by Wang et al. in this issue of Diabetes (p. 4172) suggests that myeloperoxidase (MPO) can be a trigger for obesity-associated insulin resistance, and that inhibition of MPO may offer novel pathways forward in the fight against obesity and obesity-related disease. MPO-a protein expressed by neutrophils-produces pro-oxidants like hypochlorous acid, which are normally used by neutrophils arriving at infection sites to combat bacteria and other pathogenic agents. In the early stages of obesity, however, neutrophils infiltrate adipose tissue where they can promote inflammatory processes. In this new work, investigators fed mice either a normal diet (ND) or a high-fat diet (HFD) for 16 weeks and then conducted careful studies of the resulting adipose tissue. In addition to the expected weight gain, the HFD group showed elevated ...
The US national rate of obesity has doubled since 1990, so that in 2004, nearly one-quarter of Americans (23.1 percent) were classified as obese. Medical studies have established clear links from obesity to a variety of medical conditions, including type 2 diabetes, high blood pressure, cardiovascular disease, and others. Obesity is also costly: the increasing prevalence of obesity and costs of treating obesity-related diseases has helped to fuel the recent rise in medical spending. By one estimate, 27% of the cost increase from 1987 to 2001 was due to obesity.. The latest studies estimate that obesity alone costs the US around $75 billion annually, while while the added costs of treating conditions brought on by simply being overweight bring that share up to 9.1% of total US medical expenditures. On a regional level, obesity alone costs the Northwest over $2.3 billion dollars a year. Thats around 0.5% of our gross state product (see table below). ...
Leading health organisations warn that obesity could cause 7.6 million cases of disease by 2035.. A study by the Obesity Health Alliance predicts that over the next 20 years the UK will see 4.62 million more cases of type 2 diabetes, 1.63 million new cases of coronary heart disease and 670,000 new cases of cancer.. The report, Tipping the scales: why preventing obesity makes economic sense, says that the level of obesity in 2035 would cost the NHS an added £2.5 billion.. The Obesity Health Alliance (OHA) is a coalition of more than 30 leading health organisations including the British Medical Association, Royal College of General Practitioners, Royal College of Nursing, Royal Society of Public Health, Faculty of Public Health, Diabetes UK and Cancer Research UK.. If the current trend in obesity continues, 40 million adults in the UK could be overweight or obese by 2035, including 45% of adults in the lowest income bracket.. The study didnt include several other obesity-related diseases such as ...
To investigate the modulatory effect of oolong tea polyphenols (OTP) on intestinal microbiota, OTP was prepared by column chromatography and its influence on the gut flora structure was analyzed by high-throughput sequencing with a human flora-associated high fat diet (HFD) induced obesity mouse model. We ob
THE FACTS ABOUT OBESITY IN CHILDREN & YOUNG ADULTS : The percentage of children with obesity in the United States has more than tripled since the 1970s. Today, about one in five school-aged children (ages 6-19) has obesity.Obesity is defined as having excess body fat. Overweight is defined as having excess body weight for a particular height from …. What Every Mom & Dad Should Know About Childhood ObesityRead More ». ...
Obesity is the condition of having too much body fat. Its not just a matter of appearance. Obesity can put you at risk for a variety of chronic and serious health problems. These include:. Experts say obesity is major problem in the U.S. Today more than 30 percent of U.S. adults and 20 percent of U.S. children have obesity. Children with obesity are at risk for many of the same health problems as adults with obesity.. An obesity screening may use a measurement called a BMI (body mass index) and other tests to find out if you or your child is overweight or has obesity. Being overweight means you have excess body weight. While not as severe as obesity, it may also lead to serious health problems.. ...
Dr. Ceren Yarar, postdoctoral fellow in the Department of Cell, Developmental & Integrative Biology and Nutrition Obesity Research Center at UAB, is one of four recipients of the 2012 Fall Career Enhancement Award from UABs Office of Postdoctoral Education.. The Postdoctoral Career Enhancement Award was established in 2001 to provide opportunities for postdoctoral scholars seeking to enhance their professional development. Four awards of up to $1,500 will be given to Postdoctoral Scholars, whose purpose is to fund the fellows participation in educational activities outside of UAB. Allowable expenses include: Internships of up to a 1 month period, attending extramural courses (e.g. NIH, Cold Spring Harbor, Woods Hole, etc.), to learn new skills, and visiting laboratories to conduct collaborative studies.. Dr. Yarar will be going to NIH in Bethesda for a Biotrac workshop whose purpose is to teach Protein-DNA Interactions: Gene Specific and Epigenetic Regulation of Expression of the Mammalian ...
To subscribe to the Diabetes and Obesity Research Review, go to: http://www.researchreview.co.nz/nz/Clinical-Area/Internal-Medicine/Diabetes-Obesity.aspx. ...
Potential Contributors to Obesity - Source: The Obesity Society Infographic Task Force, November 2015. Americans View on Obesity is Changing - Source: The Obesity Society Annual Meeting at ObesityWeek 2014 & ConscienHealth. Added Sugar Consumption Increased by 30% Over Three Decades in U.S. - Source: The Obesity Society Annual Meeting at ObesityWeek 2014. 65% of American Adults Recommended for Weight-Loss Treatment - Source: The Obesity Society Annual Meeting at ObesityWeek 2014. A Gap in Wellness Programs - Source: The Obesity Action Coalition & ConscienHealth. The Cost of Obesity - Source: George Washington University Institute School of Public Health ([email protected]). A Heavy Burden: The High Price of Obesity - Source: Dailyinfographic.com. Have an infographic on obesity to add to this page? Email [email protected] ...
The report also found that 12 states now have obesity rates above 30%, versus four years ago when just one state had a 30% obesity rate, TFAH and RWJF said.. Mississippi this year took the top spot as the most obese state, with Colorado falling in last place. Whats more, obesity rates have grown fastest in Oklahoma, Alabama and Tennessee, and slowest in Washington, D.C., Colorado and Connecticut.. Since 1995, when data was available for every state, obesity rates have doubled in seven states and increased by at least 90% in 10 others, TFAH and RWJF noted, adding that racial and ethnic minority adults, as well as those who are less educated and make less money, continue to garner the highest overall obesity rates.. Today, the state with the lowest obesity rate would have had the highest rate in 1995, TFAH executive director Jeff Levi said. There was a clear tipping point in our national weight gain over the last 20 years, and we cant afford to ignore the impact obesity has on our health and ...
Overweight and obesity prevalence are commonly used for public and policy communication of the extent of the obesity epidemic, yet comparable estimates of trends in overweight and obesity prevalence by country are not available. We estimated trends between 1980 and 2008 in overweight and obesity prevalence and their uncertainty for adults 20 years of age and older in 199 countries and territories. Data were from a previous study, which used a Bayesian hierarchical model to estimate mean body mass index (BMI) based on published and unpublished health examination surveys and epidemiologic studies. Here, we used the estimated mean BMIs in a regression model to predict overweight and obesity prevalence by age, country, year, and sex. The uncertainty of the estimates included both those of the Bayesian hierarchical model and the uncertainty due to cross-walking from mean BMI to overweight and obesity prevalence. The global age-standardized prevalence of obesity nearly doubled from 6.4% (95% uncertainty
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Living longer with obesity can lead to both longer hospital stays and more avoidable trips to the hospital, according to two new studies from Purdue University. Americans are overweight, and there are numerous studies that cite the problems of obesity, said Ken Ferraro, a professor of sociology. However, as the age at which people become obese continues to get younger, we wanted to know how living longer with obesity affects people.. These findings could motivate young people to reverse the trend with healthy eating and activity and, if so, they may be able to avoid the consequences of chronic obesity.. Ferraro, along with graduate student Markus Schafer, studied how obesity influences hospitalizations by using 20 years of personal health data based on surveys linked to hospital records of more than 4,000 people ages 25-77. The data, from 1971-1992, was part of a federally funded national health and nutrition survey.. In an economic sense, we have a major problem on our hands in terms of ...
To apply, one only has to create a video that details their idea in 2 minutes and 30 seconds or less, explaining why their solution is the best solution for America to implement in combatting childhood obesity, and to be available March 6-8 to come to Washington, DC, if their idea is one of three finalists. The deadline for applications is noon (Eastern) on Friday, November 16, 2012. A review committee will narrow down the field to up to 10 submissions. These top videos will be featured on the official End Childhood Obesity Innovation Challenge website where the public will vote for their favorite. In January 2013, three finalists will be named and invited to present their entrepreneurial ideas at the 2013 Building a Healthier Future Summit to a panel of judges and more than 1,000 thought leaders from multiple sectors.. I spoke with PHA Chief Marketing Officer Drew Nannis regarding his organization and the End Childhood Obesity Innovation Challenge. I expressed concern that Facebook contests can ...
The National Collaborative on Childhood Obesity Research (NCCOR) brings together four of the nations leading research funders - the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), the Robert Wood Johnson Foundation (RWJF), and the U.S. Department of Agriculture (USDA) - to address the problem of childhood obesity in America.
The National Collaborative on Childhood Obesity Research (NCCOR) brings together four of the nations leading research funders - the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), the Robert Wood Johnson Foundation (RWJF), and the U.S. Department of Agriculture (USDA) - to address the problem of childhood obesity in America.
TY - JOUR. T1 - Adipose-Resident Group 1 Innate Lymphoid Cells Promote Obesity-Associated Insulin Resistance. AU - OSullivan, Timothy E.. AU - Rapp, Moritz. AU - Fan, Xiying. AU - Weizman, Orr El. AU - Bhardwaj, Priya. AU - Adams, Nicholas M.. AU - Walzer, Thierry. AU - Dannenberg, Andrew J.. AU - Sun, Joseph C.. PY - 2016. Y1 - 2016. N2 - Innate lymphoid cells (ILCs) function to protect epithelial barriers against pathogens and maintain tissue homeostasis in both barrier and non-barrier tissues. Here, utilizing Eomes reporter mice, we identify a subset of adipose group 1 ILC (ILC1) and demonstrate a role for these cells in metabolic disease. Adipose ILC1s were dependent on the transcription factors Nfil3 and T-bet but phenotypically and functionally distinct from adipose mature natural killer (NK) and immature NK cells. Analysis of parabiotic mice revealed that adipose ILC1s maintained long-term tissue residency. Diet-induced obesity drove early production of interleukin (IL)-12 in adipose ...
In the present study we find LSG to have acceptable morbidity-rates and to be an effective procedure for weight loss and resolution of comorbidities. LSG had high resolution rates for T2DM, hypertension, hyperlipidemia, sleep apnea, musculoskeletal pain, snoring, urinary leakage and amenorrhea. The BMI and the prevalence of obesity-related diseases were stable between 12 and 24 months postoperatively. Between 85 and 90% of patients were taking some kind of vitamin and/or mineral supplement at follow-up.. In general, the reported complication rates for LSG are low despite high surgical risks in this patient group [8]. Shi et. al. systematically reviewed major perioperative complications for LSG and found a mean ± SD of 1.17 ± 1.86% for leaks and 3.57 ± 5.15% for bleeding respectively [14]. In order to reduce our leak-rate we have become particularly careful not to use heat-creating instruments close to the stomach wall at the cardia where both leaks occurred. In an attempt to reduce bleeding, ...
Nutrition, Physical Activity and Obesity Prevention … Early childhood is a critical time for obesity prevention. Since 1980, the obesity rate for children ages 6 to 11 years has more than doubled (now at 18%), and the rate for ages 12 to 19 years has quadrupled (now at 21%) (Ogden, Carroll, Kit, & Flegal, 2014). A comprehensive approach is most effective at addressing childhood obesity in schools, especially for elementary and middle school students. 1,2 Scientists know less about what school-based obesity prevention … The researchers said the failure of the programme to influence childhood obesity suggested childhood obesity prevention is unlikely to be achieved by schools alone and that wider influences from the family, community, media and the food industry must also be considered. The Journal of Childhood Obesity is an open access and peer reviewed journal that aims at providing complete and reliable information about the causes, cure, effects and prevention of childhood obesity and ...
About the Publication. The alarming rise in severe lifestyle diseases such as cardiovascular diseases, diabetes, and hypertension is commonly attributed to improper dietary habits and poor weight management. As a result, various health organizations have introduced detailed obesity management guidelines, which provide consumers information about the consumption of obesity management drugs. Growing consumer awareness about nutraceuticals that accelerate weight loss is expected to boost sales of obesity management drugs such as Bupropion and Naltrexone in the coming years. However, a mounting number of consumers believing in natural ways to promote weight loss may impact growth prospects of the obesity management market in the coming years.. Obesity is one of the most evil scourges of our modern day sedentary lifestyle. It is extremely common in certain countries in the developed world and has even begun spreading its tentacles into developing countries. In our report, Obesity Management Market: ...
Obesity contributes to Type 2 diabetes by promoting systemic insulin resistance. Obesity causes features of metabolic dysfunction in the adipose tissue that may contribute to later impairments of insulin action in skeletal muscle and liver; these include reduced insulin-stimulated glucose transport, reduced expression of GLUT4, altered expression of adipokines, and adipocyte hypertrophy. Animal studies have shown that expansion of adipose tissue alone is not sufficient to cause systemic insulin resistance in the absence of adipose tissue metabolic dysfunction. To determine if this holds true for humans, we studied the relationship between insulin resistance and markers of adipose tissue dysfunction in non-obese individuals. 32 non-obese first-degree relatives of Type 2 diabetic patients were recruited. Glucose tolerance was determined by an oral glucose tolerance test and insulin sensitivity was measured with the hyperinsulinaemic-euglycaemic clamp. Blood samples were collected and subcutaneous
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Studies of obesity and related health conditions among the Bhutanese, one of the largest refugee groups resettled in the United States in the past five years, are limited. This study examined the factors associated with excess body weight (body mass index ≥ 23 kg/m2) and abdominal obesity (waist circumference > 80 cm) in a community-based sample of 18-65 year old Bhutanese refugee women in Northeast Ohio. A Nepali-language questionnaire was used to measure socio-demographic and dietary factors. Height, weight, and waist circumference were measured to define excess body weight and abdominal obesity. The mean (±standard deviation) age of the 108 participants was 36.5 (±12.2) years and length of time in the U.S. was 19.4 (±11.9) months. Overall, 64.8% and 69.4% of the women had excess body weight and abdominal obesity, respectively. Age was significantly associated with both excess body weight (odds ratio: 1.10; 95% confidence interval: 1.05-1.16) and abdominal obesity (1.09; 1.04-1.14).
The study has two arms:. Active Comparator Arm:. Only health education. One session regarding diet restriction and physical activity with printed health education papers.. Experimental Arm:. Intensive lifestyle intervention Weekly individual session in obesity clinic (15 to 20 min.) for the first 4 weeks then one individual session in obesity clinic (10 to 20 min.) every two weeks (week 5 to week 12).. Total sessions in 12 weeks: 8 (including the final data collection visit).The components of the program: 1) Low carbohydrate (aim to achieve spontaneous reduction in calorie intake) 2) increased physical activity; 3) behavioral strategies to facilitate adherence to diet and activity prescriptions. ...
Researchers at the University of California, San Diego, School of Medicine have identified a particular subset of cells that are linked to obesity-associated insulin resistance, and that offer a promising new target for the treatment of diabetes. They showed that depletion of these cells, called CD11c-positive, in obese mice resulted in a reversal of obesity-associated insulin resistance.
Endothelial dysfunction, a pathological feature of obesity, can predict the occurrence of cardiovascular disease. The endothelial function was compared in obese, non-obese, and type 2 diabetic women, and the effect of weight loss on endothelial function in obese premenopausal women was also investigated. METHODS: Twenty type 2 diabetes patients, 35 obese and 20 non-obese non-diabetic subjects were recruited. Both the endothelium-dependent vasodilation (EDV) and endothelium-independent vasodilation (EIV) were measured. The body composition, serum lipid, serum adiponectin and resistin were also measured. Weight loss in obese women was obtained by 6 months of calorific restriction, aerobic exercise and medication (sibutramine or orlistat). RESULTS: EDV was significantly impaired in the type 2 diabetes and obese groups compared to the control group (6.0 +/- 1.3% in diabetes group, 6.7 +/- 3.9% in obese group, 12.4 +/- 4.1% in control group, P < 0.01, respectively). The mean weight loss after 6 ...
BackgroundChildhood obesity has become a global epidemic. In the recent studies has reported risk of thyroid dysfunction due to obesity. Therefore, this study intends to compare the relative frequency of thyroid function disorders in obese and overweight children with non-obese children.Materials and MethodsThis case-control study during 2015 to 2016 in Birjand, Iran was done on 137 children and adolescents (6 to 18 years), with overweight and obesity as case group and 137 non-obese subjects as control group. Body mass index (BMI), thyroid stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4) were measured, and analyzed using SPSS software version19.ResultsTSH level in obese children was significantly more (P,0.001), and FT4 (P,0.001) and FT3 levels (P=0.003), less than non-obese subjects. In the control group, 0.73 and in the case group, 2.92 of patients showed hypothyroidism disorder, that difference was not significant (P=0.177). In the control group, there was ...
Dr. José R. Fernández is a Professor and Vice Chair for Education in the Department of Nutrition Sciences. Dr. Fernández obtained his Ph.D. in Biobehavioral Health from Pennsylvania State University, training in genetics of complex traits under the advisory of Dr. Gerald McClearn and working with the three most commonly used models for genetic research: fruit flies, mice, and humans. He continued his academic training at the New York Obesity Research Center at Columbia University as a post-doctoral fellow focusing on genetics of obesity, under the mentorship of Dr. David B. Allison, and receiving specialized training in statistical models to improve the identification of genetic and environmental influences on obesity-related characteristics. Dr. Fernández joined UAB in August 2001, bringing special expertise in the application of statistical models to detect and disentangle genetic and environmental influences in obesity-related traits.. Dr. Fernandez has also been actively involved in the ...
TY - JOUR. T1 - Patterns of childhood body mass index (BMI), overweight and obesity in South Asian and black participants in the English National child measurement programme. T2 - Effect of applying BMI adjustments standardising for ethnic differences in BMI-body fatness associations. AU - Hudda, M. T.. AU - Nightingale, C. M.. AU - Donin, A. S.. AU - Owen, C. G.. AU - Rudnicka, A. R.. AU - Wells, J. C.K.. AU - Rutter, H.. AU - Cook, D. G.. AU - Whincup, P. H.. PY - 2017/11/2. Y1 - 2017/11/2. N2 - Background:The National Child Measurement Programme (NCMP) records weight and height and assesses overweight-obesity patterns in English children using body mass index (BMI), which tends to underestimate body fatness in South Asian children and overestimate body fatness in Black children of presumed African ethnicity. Using BMI adjustments to ensure that adjusted BMI was similarly related to body fatness in South Asian, Black and White children, we reassessed population overweight and obesity patterns ...
Background Polyunsaturated n-3 fatty acids (n-3 PUFAs) are reported to protect against high fat diet-induced obesity and inflammation in adipose tissue. Here we aimed to investigate if the amount of sucrose in the background diet influences the ability of n-3 PUFAs to protect against diet-induced obesity, adipose tissue inflammation and glucose intolerance. Methodology/Principal Findings We fed C57BL/6J mice a protein- (casein) or sucrose-based high fat diet supplemented with fish oil or corn oil for 9 weeks. Irrespective of the fatty acid source, mice fed diets rich in sucrose became obese whereas mice fed high protein diets remained lean. Inclusion of sucrose in the diet also counteracted the well-known anti-inflammatory effect of fish oil in adipose tissue, but did not impair the ability of fish oil to prevent accumulation of fat in the liver. Calculation of HOMA-IR indicated that mice fed high levels of proteins remained insulin sensitive, whereas insulin sensitivity was reduced in the obese mice
Obesity is associated with breast white adipose tissue (WAT) inflammation, elevated levels of the estrogen biosynthetic enzyme, aromatase, and systemic changes that have been linked to the pathogenesis of breast cancer. Here, we determined whether metabolic obesity, including changes in breast biology and systemic effects, occurs in a subset of women with normal body mass index (BMI). Breast WAT and fasting blood were collected from 72 women with normal BMI (,25 kg/m2) undergoing mastectomy for breast cancer risk reduction or treatment. WAT inflammation was defined by the presence of crown-like structures of the breast (CLS-B) which are composed of dead or dying adipocytes surrounded by macrophages. Severity of inflammation was measured as CLS-B/cm2. The primary objective was to determine whether breast WAT inflammation is associated with aromatase expression and activity. Secondary objectives included assessment of circulating factors and breast adipocyte size. Breast WAT inflammation was ...
Obesity is an established risk factor for development and progression of kidney disease. Intentional weight loss in people without kidney disease results in an improvement in diabetes, blood pressure, cholesterol, cardiovascular disease and overall death rates. The investigators do not know whether this holds true in patients with chronic kidney disease. In the proposed pilot study, the investigators will analyze if kidney function stabilizes after weight loss interventions in obese kidney disease patients and the mechanisms that might mediate this beneficial effect. If weight loss in kidney disease patients results in stabilization of kidney function, this would provide an opportunity to conduct a long-term prospective study to analyze the sustained benefits of weight loss in kidney disease patients.. Specific aim 1:. To ascertain the effects of lifestyle modification or bariatric surgery on urinary protein excretion and renal function among obese CKD patients.. Hypothesis: Weight loss attained ...
HOUSE SELECT COMMITTEE ON CHILDHOOD OBESITY REPORT TO THE 2012 REGULAR SESSION OF THE 2011 GENERAL ASSEMBLY NORTH C AROL INA G ENE R A L A S S E M B LY A LIMITED NUMBER OF COPIES OF THIS REPORT IS AVAILABLE FOR DISTRIBUTION THROUGH THE LEGISLATIVE LIBRARY. ROOMS 2126, 2226 STATE LEGISLATIVE BUILDING RALEIGH, NORTH CAROLINA 27611 TELEPHONE: (919) 733-7778 OR ROOM 500 LEGISLATIVE OFFICE BUILDING RALEIGH, NORTH CAROLINA 27603-5925 TELEPHONE: (919) 733-9390 TABLE OF CONTENTS LETTER OF TRANSMITTAL .......................................................................................................................... 1 COMMITTEE MEMBERSHIP ......................................................................................................................... 2 AUTHORIZING LEGISLATION. .................................................................................................................. 4 OVERVIEW OF COMMITTEE PRESENTATIONS ...
Predictors of Successful Weight Loss Maintenance: A Qualitative Comparative Analysis. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
TY - JOUR. T1 - Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation and insulin resistance due to enhanced macrophage c-Src signaling. AU - Sághy, Tibor. AU - Köröskényi, Krisztina. AU - Hegedűs, Krisztina. AU - Antal, Miklós. AU - Bankó, Csaba. AU - Bacsó, Zsolt. AU - Papp, Attila. AU - Stienstra, Rinke. AU - Szondy, Zsuzsa. PY - 2019/6/1. Y1 - 2019/6/1. N2 - Transglutaminase 2 (TG2) is a multifunctional protein that promotes clearance of apoptotic cells (efferocytosis) acting as integrin β3 coreceptor. Accumulating evidence indicates that defective efferocytosis contributes to the development of chronic inflammatory diseases. Obesity is characterized by the accumulation of dead adipocytes and inflammatory macrophages in the adipose tissue leading to obesity-related metabolic syndrome. Here, we report that loss of TG2 from bone marrow-derived cells sensitizes for high fat diet (HFD)-induced pathologies. We find that metabolically activated TG2 null ...
Consistent self-weighing may help individuals maintain their successful weight loss by allowing them to catch weight gains before they escalate and make behavior changes to prevent additional weight gain. While change in self-weighing frequency is a marker for changes in other parameters of weight c …
Background: Obesity is a costly condition that can reduce quality of life and increases the risk for many serious chronic diseases and premature death. The U.S. Surgeon General issued the Call to Action to Prevent and Decrease Overweight and Obesity in 2001, and in 2007, no state had met the Healthy People 2010 objective to reduce obesity prevalence among adults to 15%.. Methods: CDC used 2009 Behavioral Risk Factor Surveillance System survey data to update estimates of national and state-specific obesity prevalence. Obesity was calculated based on self-reported weight and height and defined as body mass index (weight [kg] / height [m]2) ≥30.. Results: Overall self-reported obesity prevalence in the United States was 26.7%. Non-Hispanic blacks (36.8%), Hispanics (30.7%), those who did not graduate from high school (32.9%), and persons aged 50--59 years (31.1%) and 60--69 years (30.9%) were disproportionally affected. By state, obesity prevalence ranged from 18.6% in Colorado to 34.4% in ...
The intestinal immune system is emerging as an important contributor to obesity-related insulin resistance, but the role of intestinal B cells in this context is unclear. Here, we show that high fat diet (HFD) feeding alters intestinal IgA+ immune cells and that IgA is a critical immune regulator of glucose homeostasis. Obese mice have fewer IgA+ immune cells and less secretory IgA and IgA-promoting immune mediators. HFD-fed IgA-deficient mice have dysfunctional glucose metabolism, a phenotype that can be recapitulated by adoptive transfer of intestinal-associated pan-B cells. Mechanistically, IgA is a crucial link that controls intestinal and adipose tissue inflammation, intestinal permeability, microbial encroachment and the composition of the intestinal microbiome during HFD. Current glucose-lowering therapies, including metformin, affect intestinal-related IgA+ B cell populations in mice, while bariatric surgery regimen alters the level of fecal secretory IgA in humans. These findings identify
Do you struggle with your weight? If you do, youre not alone! We see this happening more and more all over the world. There is no doubt that losing weight is going to make you feel better. We all know it is question of health also. For many people successful weight loss is a huge boost in life. People feel more energetic, creative and self confidence is higher. Here is a recent comment from a student who managed to lose 10 pounds:. This weight loss challenge has been a big contributor in improving my mental, emotional and physical condition. I have double the energy I used to and my life has completely changed. My own transformation has inspired me to research and create a lecture that challenges and educates young people and adults concerning the benefits of proper nutrition and exercise. I feel its very important to share this knowledge so that others can benefit from it also.. easy weight loss, weight loss drinks, diet programs with food, And here is another one:. To say the last three ...
The high prevalence of disease and associated weight loss at older ages limits the validity of prospective cohort studies examining the association between body mass index (BMI) and mortality. I examined mortality associated with excess weight using maximum BMI-a measure that is robust to confounding by illness-induced weight loss. Analyses were carried out on US never-smoking adults ages 50-84 using data from the National Health and Nutrition Examination Surveys (1988-1994 and 1999-2004) linked to the National Death Index through 2006. Cox models were used to estimate hazard ratios for mortality according to BMI at time of survey and at maximum. Using maximum BMI, hazard ratios for overweight (BMI, 25.0-29.9 kg/m2), obese class 1 (BMI, 30.0-34.9 kg/m2) and obese class 2 (BMI, 35.0 kg/m2 and above) relative to normal weight (BMI, 18.5-24.9 kg/m2) were 1.28 (95% confidence interval [CI], 0.89-1.84), 1.67 (95% CI, 1.15-2.40), and 2.15 (95% CI, 1.47-3.14), respectively. The corresponding hazard ratios
Obesity has reached epidemic proportions, but little is known about its influence on the intestinal immune system. Here we show that the gut immune system is altered during high-fat diet (HFD) feeding and is a functional regulator of obesity-related insulin resistance (IR) that can be exploited ther …
In 2016, male obesity prevalence for Ireland was 25.1 %. Male obesity prevalence of Ireland increased from 13.8 % in 1997 to 25.1 % in 2016 growing at an average annual rate of 3.20 %. Overweight and obesity are defined as abnormal or excessive fat accumulation that presents a risk to health. A crude population measure of obesity is the body mass index (BMI), a persons weight (in kilograms) divided by the square of his or her height (in metres). A person with a BMI of 30 or more is generally considered obese. A person with a BMI equal to or more than 25 is considered overweight. Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer. Once considered a problem only in high income countries, overweight and obesity are now dramatically on the rise in low- and middle-income countries, particularly in urban settings.
Colorado has the lowest adult obesity rate in the nation, according to a report released Monday by the non-profit Trust for Americas Health. But the states obesity rate is higher last year, up to 17.6 percent from 16.9 percent. Thats in tune with trends across the county. The report, tilted F as in Fat: How Obesity Policies are Failing in America, found no states had a decrease in obesity rates over the past year but 31 states experienced an increase. For 22 of those states it was the second year in row that obesity rates increased. The researchers looked at state and federal policies relating to health and obesity and found many to be lacking or ineffective. The country needs to develop a plan for combating obesity that is in proportion to the scope and depth of the problem, the researchers stated. This will require focusing on strategies that will work on a wide scale. The question is, is America willing to make the commitment needed to return to better health?. continued…. ...
In 2016, male obesity prevalence for Croatia was 24.1 %. Male obesity prevalence of Croatia increased from 14.4 % in 1997 to 24.1 % in 2016 growing at an average annual rate of 2.75 %. Overweight and obesity are defined as abnormal or excessive fat accumulation that presents a risk to health. A crude population measure of obesity is the body mass index (BMI), a persons weight (in kilograms) divided by the square of his or her height (in metres). A person with a BMI of 30 or more is generally considered obese. A person with a BMI equal to or more than 25 is considered overweight. Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer. Once considered a problem only in high income countries, overweight and obesity are now dramatically on the rise in low- and middle-income countries, particularly in urban settings.
The multidisciplinary Center for Childhood Obesity Prevention will strengthen ACRIs obesity research capacity and create mentoring pathways for emerging scientists who will focus on pediatric obesity.
About the BORC. The Biomedical and Obesity Research Core (BORC) is a one-stop shop core facility in the Nebraska Center for Prevention of Obesity Diseases (NPOD). The BORC provides cutting-edge biomedical research services for investigators in the University of Nebraska system and also external users in its newly renovated facility in the lower level of Leverton Hall, the NPOD headquarters building (shown at left). The BORCs new facility includes approximately 2,000 square feet of laboratory space, a state-of-the-art conference room and a collaboration zone for informal discussions. The BORC also maintains a live mouse imaging and phenotyping facility in the Life Science Annex on the University of Nebraska-Lincolns East Campus. In addition, to meet our users need for large capacity, high-speed computational solutions, the BORC is networked with the Holland Computing Center.. BORCs Goal. 1) To provide facilities, equipment, and resources that enable researchers to discover new signaling ...
One of the good-old posts around the Internet on weight loss is by Kathy Goodwin, called Successful Weight Loss: Our Top Ten Tips on What Works and Why. It is not teaching you about quick and temporary weight loss tips - Instead, their tips require quite a lot work, as those are long term weight loss methods and able
All member cities of The United States Conference of Mayors are eligible to receive this award, including service cities. Each application must include a signed letter of support from the Mayor. There is no limit on the number of applications a Mayor can support or submit.. This award aims to support programs that engage community members and promote or stimulate behavior change, in the categories of a) childhood obesity prevention, b) environmental health and sustainability or c) a hybrid of both. Types of programs eligible for funding include but are not limited to:. Childhood Obesity Prevention Initiatives. ...
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Today, childhood obesity is considered a serious and widespread struggle faced by many children around the world. In fact, childhood obesity has become an epidemic that has tripled or quadrupled in the last 40 to 50 years affecting almost 1 in 5 children. Children who are overweight are at a higher risk of suffering from hypertension, gastrointestinal problems, heart diseases and type II diabetes. Of course, on top of these health issues, obese children may further suffer from the emotional distress. Simply being labeled as fat, obese children can easily suffer from low self-esteem and depression.. When it comes to childhood obesity, parents in particular are required to take full responsibility for controlling their childs weight and must not settle with the idea that their child will later outgrow this. A great misconception among parents is that an obese child is healthier the more robust they are. This is typical amongst parents who are in denial regarding their childs weight management ...
TY - JOUR. T1 - Low circulating adropin concentrations with obesity and aging correlate with risk factors for metabolic disease and increase after gastric bypass surgery in humans. AU - Butler, Andrew A.. AU - Tam, Charmaine S.. AU - Stanhope, Kimber. AU - Wolfe, Bruce M.. AU - Ali, Mohamed R. AU - OKeeffe, Majella. AU - St-Onge, Marie Pierre. AU - Ravussin, Eric. AU - Havel, Peter J. PY - 2012/10. Y1 - 2012/10. N2 - Context: Mouse studies suggest that adropin, a peptide hormone, is required for metabolic homeostasis and prevention of obesity-associated insulin resistance. Whether obesity and insulin resistance are associated with low plasma adropin levels in humans is not known. Objectives: Our objective was to investigate the hypothesis that obesity and indicators of insulin resistance are associated with low adropin levels and determine whether weight loss regulates adropin levels. Design and Participants: Plasma was obtained from 85 female [age 21-67 yr, body mass index (BMI) 19.4-71.5 ...
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Actively Changing Together is a childhood obesity prevention program at Virginia Mason Memorial serving parents and children in Yakima.