TY - JOUR. T1 - Comparison of standard and hand-assisted laparoscopic radical nephrectomy for renal cell carcinoma.. AU - Harano, Masahiko. AU - Eto, Masatoshi. AU - Yokomizo, Akira. AU - Tatsugami, Katsunori. AU - Hamaguchi, Masumitsu. AU - Naito, Seiji. PY - 2007/11. Y1 - 2007/11. N2 - A laparoscopic radical nephrectomy (LRN) for renal cancer can be performed using two methods, hand-assisted laparoscopic surgery (HALS) and standard laparoscopic surgery (SLS). This institute initially used HALS to perform all radical nephrectomy, but gradually shifted to SLS. This study compared the two methods of radical nephrectomy: HALS vs. SLS, which were performed at a single institute. From March 1999 to November 2006, a total 129 patients with pathologically confirmed renal cell carcinoma underwent LRN, including 73 patients with the HALS and 56 patients with SLS. The median operative time was 264 minutes, and median estimated blood loss was 200 ml in the HALS group, respectively. The median operative ...

OBJECTIVE: To compare the efficiency and safety of the transperitoneal approaches with retroperitoneal approaches in laparoscopic partial nephrectomy for renal cell carcinoma and provide evidence-based medicine support for clinical treatment. METHODS: A systematic computer search of PUBMED, EMBASE, and the Cochrane Library was executed to identify retrospective observational and prospective randomized controlled trials studies that compared the outcomes of the two approaches in laparoscopic partial nephrectomy. Two reviewers independently screened, extracted, and evaluated the included studies and executed statistical analysis by using software STATA 12.0. Outcomes of interest included perioperative and postoperative variables, surgical complications and oncological variables. RESULTS: There were 8 studies assessed transperitoneal laparoscopic partial nephrectomy (TLPN) versus retroperitoneal laparoscopic partial nephrectomy (RLPN) were included. RLPN had a shorter operating time (SMD = ...

TY - JOUR. T1 - Laparoscopic partial nephrectomy with a diode laser. T2 - Porcine results. AU - Ogan, Kenneth. AU - Wilhelm, David. AU - Lindberg, Guy. AU - Lotan, Yair. AU - Napper, Cheryl. AU - Hoopman, John. AU - Pearle, Margaret S. AU - Cadeddu, Jeffrey A. PY - 2002/12. Y1 - 2002/12. N2 - Purpose: To develop a safe and effective technique for laparoscopic partial nephrectomy without need for hilar occlusion. Materials and Methods: Laparoscopic transperitoneal lower-pole partial nephrectomy was performed in five 45- to 50-kg female farm pigs using a 980-nm diode laser. Standard transperitoneal access was obtained, and a four-port approach was used to perform a laparoscopic right partial nephrectomy using a diode laser (23 W) without hilar occlusion. The pigs were allowed to recover and 2 weeks later underwent a left laparoscopic partial nephrectomy. Postoperatively, renal function was monitored by serial serum creatinine measurements. Both kidneys and ureters were removed for ex-vivo ...

TY - JOUR. T1 - Robot assisted laparoscopic partial nephrectomy. T2 - A viable and safe option in children. AU - Lee, R. S.. AU - Sethi, A. S.. AU - Passerotti, C. C.. AU - Retik, A. B.. AU - Borer, J. G.. AU - Nguyen, H. T.. AU - Peters, Craig A. PY - 2009/1/1. Y1 - 2009/1/1. N2 - Purpose: The safety, benefits and usefulness of laparoscopic partial nephrectomy have been demonstrated in the pediatric population. We describe our technique, and determine the safety and feasibility of robot assisted laparoscopic partial nephrectomy based on our initial experience. Materials and methods: We retrospectively reviewed robot assisted laparoscopic partial nephrectomy performed at our institution between 2002 and 2005. The technique was conducted via a transperitoneal approach with the da Vinci Surgical System using standard laparoscopic procedural steps. Clinical indicators of outcomes included estimated blood loss, complications, in hospital narcotic use and length of stay. Results: Robot assisted ...

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TY - JOUR. T1 - Short-term administration of diclofenac sodium affects renal function after laparoscopic radical nephrectomy in elderly patients. AU - Mizuno, Tomohiro. AU - Ito, Kazuma. AU - Miyagawa, Yasuhiro. AU - Ishikawa, Kazuhiro. AU - Suzuki, Yasuhiro. AU - Mizuno, Masashi. AU - Ito, Yasuhiko. AU - Funahashi, Yasuhito. AU - Hattori, Ryohei. AU - Gotoh, Momokazu. AU - Yamada, Kiyofumi. AU - Noda, Yukihiro. N1 - Copyright: Copyright 2013 Elsevier B.V., All rights reserved.. PY - 2012/11. Y1 - 2012/11. N2 - Objective: Non-steroidal anti-inflammatory drugs decrease the glomerular filtration rate. However, few studies have been conducted on renal function in patients treated with non-steroidal anti-inflammatory drugs during the first week after laparoscopic radical nephrectomy. The purpose of this study is to determine whether short-term administration of non-steroidal anti-inflammatory drugs during the first week after laparoscopic radical nephrectomy is a risk factor for impaired renal ...

TY - JOUR. T1 - Does Obesity Impact the Costs of Partial and Radical Nephrectomy?. AU - Bensalah, Karim. AU - Raman, Jay D.. AU - Bagrodia, Aditya. AU - Marvin, Andrea. AU - Lotan, Yair. PY - 2008/5/1. Y1 - 2008/5/1. N2 - Purpose: We analyzed the impact of obesity on the costs of partial and radical nephrectomy. Materials and Methods: The charts of 237 patients who underwent open radical nephrectomy (48), laparoscopic radical nephrectomy (67), open partial nephrectomy (61) or laparoscopic partial nephrectomy (61) were retrospectively reviewed. Clinical data were collected, including age, American Society of Anesthesiologists score, body mass index, tumor size, complications and length of stay. Cost data comprised total direct costs and subcosts, including anesthesia, laboratory, operating room service, radiology, room and board, pharmacy and surgical supplies. Obese and nonobese patients were compared in each group using the Mann-Whitney U and chi-square tests for continuous and categorical ...

Introduction: The surgical standard of care for favorably located, small renal tumors is partial nephrectomy. As the incidence of renal cell carcinoma (RCC) and earlier incidental detection of small kidney masses has steadily risen over the past twenty years, minimally-invasive management of these lesions has become more common. We report our single institution experience with hand-assisted laparoscopic partial nephrectomy (HALPN) as compared with traditional open partial nephrectomy (OPN ...

After a median follow-up of 62 months, 25.3% of patients treated with partial nephrectomy had died, compared with 41.5% of patients treated with radical nephrectomy. Patients treated with partial nephrectomy had a 46% lower risk of death.. Regardless of the type of surgery, patients had an equal chance of dying from kidney cancer, suggesting that each type of surgery was likely to cure the cancer. Kidney cancer was the cause of death for 1.9% of partial nephrectomy patients and 4.3% of radical nephrectomy patients. The survival discrepancy was found in death from any cause.. With the increased use of x-rays and CT scans (for unrelated reasons), the identification of early stage kidney cancer has become more common-making it important to weigh the risks and benefits of partial versus radical nephrectomy. Partial nephrectomy is a more technically challenging procedure and is associated with more short-term complications. Radical nephrectomy, on the other hand, can increase the risk of chronic ...

MEYER, Fernando et al. Early outcomes of laparoscopic donor nephrectomy with multiple renal arteries. Int. braz j urol. [online]. 2012, vol.38, n.4, pp.496-503. ISSN 1677-6119. http://dx.doi.org/10.1590/S1677-55382012000400009.. PURPOSE: We evaluated our experience with laparoscopic donor nephrectomy in patients with multiple renal arteries, comparing operative outcomes and early graft function with patients with a single renal artery. MATERIALS AND METHODS: From January 2003 to February 2009, 130 patients underwent laparoscopic donor nephrectomy at our institution, 108 (83%) with a single renal artery and 22 (17%) with multiple arteries. Donor and recipient outcomes for single artery and multiple arteries allografts were compared. RESULTS: The LDN operative time was similar between the single artery and multiple arteries groups (162 vs 163 min, respectively, p = 0.87). Allografts with multiple arteries had significantly longer warm ischemia time (3.9 vs 4.9 min, p = 0.05) and cold ischemia time ...

TITLE: A Review of Perioperative Complications In 120 Consecutive Community Based Laparoscopic Donor Nephrectomies. INTRODUCTION: Throughout the mid 1990s and early 2000s numerous university programs compared perioperative complications in laparoscopic donor to the gold standard open technique in order to validate the emerging standard of care for nephrectomies. As innovation becomes the norm, an important question yet to be answered in the literature is how the complication rate at a community hospital performing donor nephrectomies compares to the larger academic centers now that laparoscopic nephrectomies are universally performed.. METHODS: All the charts from patients undergoing laparoscopic nephrectomies between January 1, 2006 and December 31, 2008 were reviewed. The examined outcomes were operative time, estimated blood loss, intra-and post operative complications, and length of hospital stay. The results were stratified in order to compare them with national figures using statistical ...

Right donor nephrectomy,especially when conducted laparoscopically,has not been accepted by most transplant surgeons because of the consequent short right renal vein and the possible increased incidence of venous thrombosis and other surgical complications. We have evaluated our outcomes of Hand Assisted Laparoscopic Donor nephrectomy (HALD) and we compared between right and left donor nephrectomy.HALD has been performed at our institution since December,1999.Through May 2014, a total of 1,500 HALD procedures have been performed.We decided to perform right donor nephrectomy when there is complex left renal vascular anatomy, the right kidney has a benign pathology, the right kidney is smaller than the left , 20% or the function of the right kidney is less than the left by , 20%.Right Donor Nephrectomy (RDN) was performed in 272 patients and Left Donor Nephrectomy (LDN) was performed in 1,228 patients. Mean donor age was 40.5(18.8-66.9) for RDN group and 40.9(18.5-68.5) for LDN group, BMI was ...

TY - JOUR. T1 - Outcomes of laparoscopic radical nephrectomy in the setting of vena caval and renal vein thrombus. T2 - Seven-year experience. AU - Martin, George Lee. AU - Castle, Erik P.. AU - Martin, Aaron D.. AU - Desai, Premal J.. AU - Lallas, Costas D.. AU - Ferrigni, Robert G.. AU - Andrews, Paul E.. PY - 2008/8/1. Y1 - 2008/8/1. N2 - Purpose: We present our experience with laparoscopic radical nephrectomy for T3b disease focusing on thrombus within the vena cava. Patients and Methods: A total of 14 patients with T3b disease were identified from a retrospective laparoscopic renal cancer database from 2000 to 2007. Patient demographics, clinical stage, preoperative imaging, intraoperative parameters, final pathology, and postoperative course were analyzed. In patients with a large tumor thrombus, the infraumbilical extraction excision was performed early and a gel port was placed. This was used when laparoscopic milking or determination of the distal extent of the tumor thrombus was ...

TY - JOUR. T1 - Is routine postoperative chest radiography needed after open nephrectomy?. AU - Latchamsetty, Kalyan C.. AU - La Rochelle, Jeffrey C.. AU - Hoeksema, Jerome. AU - Coogan, Christopher L.. PY - 2005/2. Y1 - 2005/2. N2 - Objectives. To assess whether routine postoperative chest radiography (CXR) is required after open nephrectomy for the detection and possible management of a pneumothorax. It has become the standard of care by many urologists to obtain routine postoperative CXRs after open nephrectomy to assess for the presence of a pneumothorax. However, at our institution, very few patients have developed a pneumothorax postoperatively, and, furthermore, the CXR findings almost never affected the clinical management. Methods. Retrospective data were collected on the last 150 open nephrectomies performed by two urologists at our institution. All laparoscopic nephrectomies and thoracoabdominal nephrectomies were excluded from analysis. Results. A total of 150 patients underwent open ...

Objective: Open radical nephrectomy can be performed through midline or chevron incision. This study aims to compare the quality of life between midline and chevron incision in open radical the nephrectomy since comparison studies between these approach focused on quality life are still lacking.. Methods: This study includes total 31 patients that underwent open radical nephrectomy in Cipto Mangunkusumo Hospital Indonesia. The subjects were divided into midline and chevron groups using simple random sampling. Modified WHOQOL BREF and VAS pain score were compared between these groups.. Results: Total 31 subjects included, with a male: female ratio 2.33:1 and age mean 49.81±13.1 with the incidence are highest at 41-60 years old. In our study, most subjects were diagnosed in T3-T4 with 58,07% overall. Clear cell renal cell carcinoma is the most frequent pathology result with 41,93% followed by Paper Renal cell Carcinoma 12.90%. VAS score is higher in Chevron group with result 2,47±1,40 compare to ...

TY - JOUR. T1 - Open live donor nephrectomy. T2 - Current status. AU - Barry, John. PY - 2005/3. Y1 - 2005/3. KW - Donor nephrectomy techniques. KW - Laparoscopic donor nephrectomy. KW - Living kidney donation. KW - Open donor nephrectomy. UR - http://www.scopus.com/inward/record.url?scp=14644436358&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=14644436358&partnerID=8YFLogxK. M3 - Article. C2 - 15720336. AN - SCOPUS:14644436358. VL - 95. SP - 56. EP - 58. JO - BJU International, Supplement. JF - BJU International, Supplement. SN - 1465-5101. IS - 2. ER - ...

TY - JOUR. T1 - R-LESS partial nephrectomy trifecta outcome is inferior to multiport robotic partial nephrectomy. T2 - Comparative analysis. AU - Komninos, Christos. AU - Shin, Tae Young. AU - Tuliao, Patrick. AU - Yoon, Young Eun. AU - Koo, Kyo Chul. AU - Chang, Chien Hsiang. AU - Kim, Sang Woon. AU - Ha, Ji Yong. AU - Han, Woong Kyu. AU - Rha, Koon Ho. PY - 2014/9. Y1 - 2014/9. N2 - Background Trifecta achievement in partial nephrectomy (PN) is defined as the combination of warm ischemia time ≤20 min, negative surgical margins, and no surgical complications. Objective To compare trifecta achievement between robotic, laparoendoscopic, single-site (R-LESS) PN and multiport robotic PN (RPN). Design, setting, and participants Data from 167 patients who underwent RPN from 2006 to 2012 were retrospectively analyzed. Outcome measurements and statistical analysis Primary outcome measurement was trifecta achievement; secondary outcome was the perioperative and postoperative comparison between groups. ...

Partial nephrectomy is most often performed through a flank incision. Whilst keyhole surgery is suitable for total nephrectomy, for technical reasons it is far more difficult to perform a partial nephrectomy via a keyhole approach. Even in the most experienced hands, laparoscopic partial nephrectomy is associated with a higher complication rate than open partial nephrectomy.. After the kidney is exposed, its blood supply is temporarily interrupted by means of specially designed clamps. The kidney is then bathed in ice. This preserves kidney function whilst its blood supply is temporarily halted. This cannot be done via a laparoscopic approach, resulting in a higher risk of losing functioning kidney cells. Once the kidney has been cooled, the cancer is then carved out of the kidney and specimens are taken from the kidney for immediate analysis by a pathologist (frozen section analysis) to ensure that no cancer has been left behind. The kidney is then repaired and the blood supply into the ...

TY - JOUR. T1 - Technique of Right Laparoscopic Donor Nephrectomy. T2 - A Single Center Experience. AU - Johnson, Mark W.. AU - Andreoni, Kenneth. AU - McCoy, Lynn. AU - Scott, Lisa. AU - Rodegast, Beverly. AU - Friedman, Elizabeth. AU - Thomas, Suzanne. AU - Salm, Jane. AU - Gerber, David A.. AU - Fair, Jeffrey. PY - 2001/9. Y1 - 2001/9. N2 - The majority of laparoscopic donor nephrectomies (LDNs) are limited to the left side due to technical and allograft concerns in using the right. We review our experience with right LDNs. Since June 1997, 15 right LDNs were performed and the records retrospectively reviewed for demographics, operative time, transfusions, complications, and length of stay. Recipient records were also reviewed for delayed graft function, complications, and serum creatinine levels. Overall donor, recipient and graft survivals at 6 months are 100%. Mean operative time was 317±11.0 min, length of stay was 4.2±0.2 d, and mean serum creatinine levels at discharge, 1, 3, and 6 ...

TY - JOUR. T1 - Value of Nephrometry Score Constituents on Perioperative Outcomes and Split Renal Function in Patients Undergoing Minimally Invasive Partial Nephrectomy. AU - Watts, Kara L.. AU - Ghosh, Propa. AU - Stein, Solomon. AU - Ghavamian, Reza. PY - 2017/1/1. Y1 - 2017/1/1. N2 - Objective To assess the relationship between individual nephrometry score (NS) constituents (RENAL) on perioperative outcomes and renal function of the surgical kidney in patients undergoing laparoscopic partial nephrectomy or robotic-assisted partial nephrectomy. Materials and Methods Two hundred forty-five patients who underwent laparoscopic partial nephrectomy or robotic-assisted partial nephrectomy between 2005 and 2014 were retrospectively reviewed. Each renal mass NS was calculated from preoperative computed tomography imaging. Multivariate regression analysis was used to evaluate the effect of NS variables on perioperative outcomes and change in overall renal function (as estimated by glomerular ...

TY - JOUR. T1 - Use of Haemostatic Agents and Glues during Laparoscopic Partial Nephrectomy. T2 - A Multi-Institutional Survey from the United States and Europe of 1347 Cases{A figure is presented}. AU - Breda, Alberto. AU - Stepanian, Sevan V.. AU - Lam, John S.. AU - Liao, Joseph C.. AU - Gill, Inderbir S.. AU - Colombo, Jose R.. AU - Guazzoni, Giorgio. AU - Stifelman, Michael D.. AU - Perry, Kent T.. AU - Celia, Antonio. AU - Breda, Guglielmo. AU - Fornara, Paolo. AU - Jackman, Stephen V.. AU - Rosales, Antonio. AU - Palou, Juan. AU - Grasso, Michael. AU - Pansadoro, Vincenzo. AU - Disanto, Vincenzo. AU - Porpiglia, Francesco. AU - Milani, Claudio. AU - Abbou, Claude C.. AU - Gaston, Richard. AU - Janetschek, Gunter. AU - Soomro, Naeem A.. AU - De la Rosette, Jean J.. AU - Laguna, Pilar M.. AU - Schulam, Peter G.. PY - 2007/9/1. Y1 - 2007/9/1. N2 - Objectives: Laparoscopic partial nephrectomy (LPN) is a technically challenging procedure for the management of renal tumours. Major complications ...

The purpose of this study is presenting a method to predict the presence of an open urinary tract and the position of the opening in laparoscopic partial nephrectomy from three dimensional (3D) computed tomography (CT) images by using novel image segmentation and visualization techniques. From CT images of patients who underwent laparoscopic partial nephrectomy, 3D regions of the kidney, urinary tract, and tumor were segmented. For each patient, multiple virtual resection planes of the kidney with different surgical margins (1 mm to 5 mm, every 1 mm) were generated and the presence of an open urinary tract and the position of the opening were predicted from the images. We compared the predictions with actual operations in 5 cases by using recorded video of the operations and operative notes. In terms of the presence of an open urinary tract, agreement of the predictions and the intraoperative results was obtained in all patients. The expected positions of the openings were close to those in the actual

Issuu is a digital publishing platform that makes it simple to publish magazines, catalogs, newspapers, books, and more online. Easily share your publications and get them in front of Issuus millions of monthly readers. Title: Laparoscopic Partial Nephrectomy for Central Tumors, Author: urovideo urovideo, Name: Laparoscopic Partial Nephrectomy for Central Tumors, Length: 10 pages, Page: 1, Published: 2011-03-30

TY - JOUR. T1 - Outcomes of Laparoscopic and Robotic Partial Nephrectomy for Large (,4 Cm) Kidney Tumors. T2 - Systematic Review and Meta-Analysis. AU - Pavan, Nicola. AU - Derweesh, Ithaar H.. AU - Mir, Carme Maria. AU - Novara, Giacomo. AU - Hampton, Lance J.. AU - Ferro, Matteo. AU - Perdonà, Sisto. AU - Parekh, Dipen J.. AU - Porpiglia, Francesco. AU - Autorino, Riccardo. PY - 2017/8. Y1 - 2017/8. N2 - Purpose: The aim of this study was to assess the outcomes of minimally invasive (laparoscopic and robotic) partial nephrectomy (MIPN) for large renal masses. Materials and Methods: A systematic literature review was performed up to September 2016 using multiple search engines to identify studies comparing MIPN for tumors larger than 4 cm (,cT1a) with MIPN for tumors smaller than 4 cm (cT1a). The preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria were used for article selection. Baseline demographics and surgical, functional, and oncological parameters were ...

TY - JOUR. T1 - Outcomes of Laparoscopic and Robotic Partial Nephrectomy for Large (,4 Cm) Kidney Tumors. T2 - Systematic Review and Meta-Analysis. AU - Pavan, Nicola. AU - Derweesh, Ithaar H.. AU - Mir, Carme Maria. AU - Novara, Giacomo. AU - Hampton, Lance J.. AU - Ferro, Matteo. AU - Perdonà, Sisto. AU - Parekh, Dipen J.. AU - Porpiglia, Francesco. AU - Autorino, Riccardo. PY - 2017/8/1. Y1 - 2017/8/1. N2 - Purpose: The aim of this study was to assess the outcomes of minimally invasive (laparoscopic and robotic) partial nephrectomy (MIPN) for large renal masses. Materials and Methods: A systematic literature review was performed up to September 2016 using multiple search engines to identify studies comparing MIPN for tumors larger than 4 cm (,cT1a) with MIPN for tumors smaller than 4 cm (cT1a). The preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria were used for article selection. Baseline demographics and surgical, functional, and oncological parameters ...

TY - JOUR. T1 - Endourologist at work. T2 - Laparoscopic placement of drains after nephrectomy. AU - Moran, M. E.. AU - Low, Roger. AU - Kim, C. A.. PY - 1993. Y1 - 1993. N2 - The exact indications and ideal candidates for laparoscopic nephrectomy are yet to be identified. Occasionally, urologists might drain the renal fossa, depending on the pathogenesis of the renal disease prompting the nephrectomy, as with chronic infection. The authors describe a technique of placing a closed drainage system under full view with insufflation after laparoscopic nephrectomy. No additional stab wounds are necessary.. AB - The exact indications and ideal candidates for laparoscopic nephrectomy are yet to be identified. Occasionally, urologists might drain the renal fossa, depending on the pathogenesis of the renal disease prompting the nephrectomy, as with chronic infection. The authors describe a technique of placing a closed drainage system under full view with insufflation after laparoscopic nephrectomy. No ...

TY - JOUR. T1 - Predicting the development of surgically induced chronic kidney disease after total nephrectomy using body surface area-adjusted renal cortical volume on CT angiography. AU - You, Sung Hye. AU - Sung, Deuk Jae. AU - Yang, Kyung Sook. AU - Kim, Myung-Gyu. AU - Han, Na Yeon. AU - Park, Beomjin. AU - Kim, Min Ju. PY - 2019/2/1. Y1 - 2019/2/1. N2 - OBJECTIVE. The purpose of this study was to predict the probability of surgically induced chronic kidney disease (CKD) developing in patients who underwent total nephrectomy by measuring the body surface area (BSA)-adjusted renal cortical volume (RCV) with preoperative CT angiography (CTA). MATERIALS AND METHODS. A total of 105 patients with a normal preoperative estimated glomerular filtration rate (eGFR) who underwent preoperative CTA and subsequent total nephrectomy for kidney donation (n = 67) or a renal tumor (n = 38) were included in this retrospective study. Patients were divided into group A (patients without surgically induced ...

Objectives: Based on imaging features, nephrometry scoring systems have been conceived to create a standardized and reproducible way to characterize renal tumor anatomy. However, less is known about which of these individual measures are important with regard to clinically relevant perioperative outcomes such as ischemia time (IT), estimated blood loss (EBL), length of hospital stay (LOS), and change in estimated glomerular filtration rate (eGFR) after robotic partial nephrectomy (PN). We aimed to assess the utility of the RENAL and PADUA scores, their subscales, and C-index for predicting these outcomes. Materials and Methods: We analyzed imaging studies from 283 patients who underwent robotic PN between 2008 and 2014 to assign nephrometry scores (NS): PADUA, RENAL and C-index. Univariate linear regression was used to assess whether the NS or any of their subscales were associated with EBL or IT. Multivariable linear regression and linear regression models were created to assess LOS and eGFR. ...

BACKGROUND: The two major life-threatening complications associated with laparoscopic live donor nephrectomy are sudden severe bleeding and intestinal injury. A combined technique-hand-assisted and retroperitoneoscopic (HARS)-reduces the risk of these life-threatening complications. In this study, we report on our experience from the first 75 consecutive HARS operations. METHODS: The data has been collected prospectively according to intention to treat and includes all consecutive donors operated with the HARS technique. Warm ischemia time, operating time, and blood loss were recorded. Complications, convalescence, and allograft outcome were followed postoperatively with a mean follow-up of 701 (range 60-1438) days. RESULTS: The mean operating time was 138 (range 85-260) minutes and the mean warm ischemia time 175 (85-510) seconds. The operative time was significantly longer in male donors. The mean bleeding was 176 (50-700) ml. There were no conversions to open surgery. Major complications ...

Care guide for Laparoscopic Live Donor Nephrectomy (Aftercare Instructions). Includes: possible causes, signs and symptoms, standard treatment options and means of care and support.

TY - JOUR. T1 - Use of the Satinsky clamp for hilar clamping during robotic partial nephrectomy. T2 - indications, technique, and multi-center outcomes. AU - Abdullah, Newaj. AU - Rahbar, Haider. AU - Barod, Ravi. AU - Dalela, Deepansh. AU - Larson, Jeff. AU - Johnson, Michael. AU - Mass, Alon. AU - Zargar, Homayoun. AU - Kaouk, Jihad. AU - Allaf, Mohamad E. AU - Bhayani, Sam. AU - Stifelman, Michael. AU - Rogers, Craig. PY - 2016/6/21. Y1 - 2016/6/21. N2 - A Satinsky clamp may be a backup option for hilar clamping during robotic partial nephrectomy (RPN) if there are challenges with application of bulldog clamps, but there are potential safety concerns. We evaluate outcomes of RPN using Satinsky vs. bulldog clamps, and provide tips for safe use of the Satinsky as a backup option. Using a multi-center database, we identified 1073 patients who underwent RPN between 2006 and 2013, and had information available about method of hilar clamping (bulldog clamp vs. Satinsky clamp). Patient baseline ...

Sirs,. We read with great interest the study by Neuhaus et al. reporting on live kidney donors (that had donated by open nephrectomy) and their high degree of satisfaction with the predonation decision-making process, along with improved postdonation relationships with their partners and the recipient children [1].. One question that this valuable and insightful study was unable to answer was whether the recent introduction of the less invasive laparoscopic technique (which has rapidly become the standard of care) [2, 3] has had any additional effects on the decision-making process and postoperative family dynamics and quality of life of those donating a kidney to a pediatric recipient. Interestingly, in adult-to-adult live donor kidney transplantation, several studies have demonstrated that laparoscopic live donor nephrectomy does not only significantly decrease postoperative morbidity [4], but may therefore also have contributed to the steady increase of live donor kidney transplants... ...

INTRODUCTION. Partial nephrectomy is the gold standard for treating patients with suspicious renal lesions. More_x000D_ recently, ablative the technologies have come into vogue as a minimally invasive means to address the mall_x000D_ renal mass. In this video, we demonstrate our technique for a salvage partial nephrectomy in a case of failed_x000D_ cryo-therapy for suspected renal cell carcinoma.. METHODS. The case a is a 49 year old male who in 2011 had a cryo-ablation of a left upper pole renal mass in conjunction with a left sided laparoscopic bowel resection for cancer. Follow up MRI in 2015 demonstrated a bilobar mass in the postero-medial aspect of the left kidney- the previous site of cryo-therapy. The mass had_x000D_ a non-enhancing exophytic component (previously ablated) as well as an enhancing endophytic region suspicious for RCC. He was taken to the operating room for a partial nephrectomy, and his chart was pulled and retrospectively examined.. RESULTS. Operative time was just over ...

TY - JOUR. T1 - Challenging situations in partial nephrectomy. AU - Raison, Nicholas Tobias Johannes. AU - Doeuk, Norbert. AU - Malthouse, Theo. AU - Kasivisvanathan, Veeru. AU - Lam, Wayne. AU - Challacombe, Benjamin. PY - 2016/6/2. Y1 - 2016/6/2. N2 - Although most partial nephrectomies are performed as primary procedures in the elective or semi-imperative setting on kidneys with relatively normal anatomy, this is not always the case.The indications for partial nephrectomy continue to expand and it is becoming particularly relevant in patients with single functioning kidneys, poor kidney function, anatomical anomalies and hereditary syndromes predisposing to multiple kidney cancers, such as Von Hippel-Lindau syndrome. These, along with previous abdominal surgery, pose surgical challenges. In this article we offer advice as to how to tackle these unusual situations.An ability to master the whole range of indications will allow the modern upper renal tract surgeon to offer partial nephrectomy to ...

article{55e5a881-1a75-4904-a5ea-2d49b2125518, abstract = {,p,Introduction: To evaluate the role of the surgical technique used for the treatment of benign renal tumors, with regard to renal function and overall survival (OS) in patients without cancer-related mortality. Technical considerations: The study included 506 patients, mean age of 63.3 years, with histologically proven benign renal lesions originating from 5 European centers. Retrospective data from each hospital were retrieved and merged into a common database for analyses. OS, American Society of Anesthesiology score, and renal functions were measured in relation to surgical technique. The Mann-Witney U-test, the paired t-test, and Coxs multivariate analysis were used.Patients treated with radical nephrectomy had significantly reduced renal function postoperatively compared with nephron sparing surgery (NSS). OS was significantly reduced after radical nephrectomy compared with NSS (P = .012), a survival difference that remained ...

TY - JOUR. T1 - Robotic Partial Nephrectomy for a Peripheral Renal Tumor. AU - Cooper, Caleb A.. AU - Shum, Cheuk Fan. AU - Sundaram, Chandru. PY - 2018/5/1. Y1 - 2018/5/1. N2 - Partial nephrectomy (PN) is the preferred surgical treatment for T1 renal tumors whenever technically feasible. When properly performed, it allows preservation of nephron mass without compromising oncologic outcomes. This reduces the postoperative risk of renal insufficiency, which translates into better overall survival for the patients. PN can be technically challenging, because it requires the surgeon to complete the tasks of tumor excision, hemostasis and renorrhaphy, all within an ischemic time of preferably below 30 minutes. The surgeon needs to avoid violating the tumor margins while leaving behind the maximal parenchymal volume at the same time. Variations such as zero ischemia, early unclamping, and selective clamping have been developed in an attempt to reduce the negative impact of renal ischemia, but ...

BACKGROUND: Transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Live donor nephrectomy is performed on healthy individuals who do not receive direct therapeutic benefit of the procedure themselves. In order to guarantee the donors safety, it is important to optimise the surgical approach. Recently we demonstrated the benefit of laparoscopic nephrectomy experienced by the donor. However, this method is characterised by higher in hospital costs, longer operating times and it requires a well-trained surgeon. The hand-assisted retroperitoneoscopic technique may be an alternative to a complete laparoscopic, transperitoneal approach. The peritoneum remains intact and the risk of visceral injuries is reduced. Hand-assistance results in a faster procedure and a significantly reduced operating time. The feasibility of this method has been demonstrated recently, but as to date there are no data available advocating the use of one technique above the ...

Renal cell carcinoma (RCC) is a tumor with clinically apparent immunologic phenomena, such as response to immunotherapies (interferon, interleukin-2, immune cellular therapy etc), spontaneous regression, and sometimes indolent behaviour. Nephrectomy itself influences the prognosis of advanced RCC patients as shown in 2 randomised trials, and could have an immune basis. We previously reported on the variability of clinical behaviour in advanced RCC patients who had not received systemic treatment after debulking nephrectomy (Debulking Nephrectomy Followed By A Watch And Wait Approach In Metastatic Renal Cell Carcinoma .Wong A, et al. Urol Oncol, in press). The clinical significance of this includes the avoidance of toxic systemic therapies after nephrectomy, or the possibility of using non-toxic vaccine approaches in metastatic patients after cytoreductive nephrectomy. In this research proposal we would like to analyse the immune related gene expression profile on nephrectomy tumor samples and ...

The goals of this article are (1) to review the history and evolution of laparoscopic radical nephrectomy (LRN) as a minimally invasive option for the treatment of renal cell carcinoma (RCC), (2) to provide the surgeon with a working knowledge of laparoscopy, as well as a clear description of how to perform an LRN successfully, and (3) to ans...

TY - JOUR. T1 - The development of a laparoscopic donor nephrectomy program in a de novo renal transplant program. T2 - Evolution of technique and results in over 200 cases.. AU - Lallas, Costas D.. AU - Castle, Erik P.. AU - Schlinkert, Richard T.. AU - Andrews, Paul E.. PY - 2006/1/1. Y1 - 2006/1/1. N2 - BACKGROUND AND OBJECTIVES: In 1999, our institution began a kidney transplant program with collaboration between the departments of General Surgery/Transplantation and Urology. From the onset, donor nephrectomies were performed laparoscopically and are currently the domain of Urology, which had no prior laparoscopic experience before this undertaking. We reviewed our experience. METHODS: A database of our experience was kept prospectively from June 1999 to November 2004. Records of both donors and recipients were reviewed. Special attention was directed toward our changes in technique and their relationship to outcomes, with emphasis on graft extraction and overall complication rates. RESULTS: ...

Nephrectomy ir ķirurģiskās izņemšanas no nierēm, orgāns, kas filtri atkritumi no asinīm un ražo urīnu. Ir divas nieres, pa labi un pa kreisi. Katrs ir apmēram 4 collas līdz 5 collas garš. Tie atrodas aizmugurē vēdera, tieši zem diafragmas, aiz aknas labajā, un liesas pa kreisi. Daļa no katras nieres aizsargā zemākajām vienu vai divām ribām un muskuļos, kas aptver atpakaļ un ķermeņa pusi. Atkarībā no iemesla par nephrectomy, visas vai daļu no vienas nieres vai abas nieres tiks noņemts; Daļēja nephrectomy - daļa no vienas nieres izņem .; Simple nephrectomy - viss vienā nieres izņem .; Radical nephrectomy - viss vienā nieres noņem kopā ar blakus virsnieru dziedzera (adrenalīns ražošanas dziedzeris, kas atrodas virs nierēm) un kaimiņu limfmezgli .; Divpusējā nephrectomy - Abas nieres ir izņemtas.. Kad apmeklēt ārstu. Kad esat atgriezies mājās no slimnīcas, nekavējoties, ja zvaniet savam ārstam. ...

TY - JOUR. T1 - Progressive glomerular sclerosis and renal failure in rat with 7/8 nephrectomy model. AU - Makino, Hirofumi. AU - Theng, Long Zhu. AU - Kumagai, Isao. AU - Takatori, Katsuhiko. AU - Ota, Zensuke. AU - Yoshifusa, Hiroto. PY - 1990/1. Y1 - 1990/1. N2 - A model of progressive glomerular sclerosis and chronic renal failure was established in 7/8 nephrectomized rats. Three fourths of left kidney of six-week old Sprague Dawley rats were ligated and removed. One week later right kidney was removed. As controls 3/4 nephrectomized rats operated the same manner as 7/8 nephrectomized rats and sham operated rats were used. Remarkable excretion of the protein into the urine and rise in blood pressure were noted in all 7/8 nephrectomized rats. Eight weeks after 7/8 nephrectomy, serum creatinine rose as high as 2.8-0.3 mg/dl and BUN 260 + 65 mg/dl. In contrast, only minor degree of elevation of blood pressure, excretion of protein into the urine and elevation of serum creatinine were noted in ...

VR and partial nephrectomy, kidney cancer, renal cancer, robotic surgery, 3D purpose-built models, VR Models for robotic-assisted partial nephrectomy.

TY - JOUR. T1 - Partial Nephrectomy. T2 - Technique Complications and Pathological Findings. AU - Polascik, Thomas J.. AU - Pound, Charles R.. AU - Meng, Maxwell V.. AU - Partin, Alan W.. AU - Marshall, Fray F.. PY - 1995/10. Y1 - 1995/10. N2 - Purpose: We evaluate whether partial nephrectomy can be performed safely and efficaciously for renal tumors. Materials and Methods: The results of 67 partial nephrectomies performed between 1977 and 1994 for renal cell carcinoma (51), oncocytoma (9), angiomyolipoma (3), transitional cell carcinoma (3) and other nonneoplastic lesions (2) were analyzed retrospectively in detail. Results: Diminished complication rates were noted after 1988, and were attributed to improvements in surgical technique and an increased incidence of smaller, serendipitously discovered tumors. Although 35.5 percent of the patients had preoperative renal impairment (mean serum creatinine 2.1 mg./dl.), there were minimal changes in renal function and no patient required acute ...

Danzig M.R., Ghandour R.A., Chang P., Wagner A.A., Pierorazio P.M., Allaf M.E., McKiernan J.M.. Journal of Urology 2015 194:4 (903-909). Purpose: We compared renal function outcomes among patients in the surveillance and intervention arms of the DISSRM registry. Materials and Methods Patients were grouped into chronic kidney disease stages by estimated glomerular filtration rate range. Cases were considered up staged if a more advanced chronic kidney disease stage was entered during followup. Chronic kidney disease up staging-free survival was compared among groups using Kaplan-Meier analysis and paired comparisons log rank tests. Multivariate Cox regression identified independent predictors of chronic kidney disease up staging-free survival. Results A total of 162 patients met the study inclusion criteria, with 68 in the surveillance arm, 65 undergoing partial nephrectomy, 15 undergoing radical nephrectomy and 14 undergoing cryoablation. Median tumor size was 2.2 cm. Mean estimated glomerular ...

Chemical nephrectomy - What exactly is a partial nephrectomy? Kidney surgery. Partial nephrectomy refers to surgical removal of part of the kidney, usually because of a small tumor/abnormal growth of the kidney. A radical nephrectomy (total kidney removal) is done for larger tumors, or if the partial nephrectomy is not technically possible.

Best retroperitoneoscopic simple nephrectomy hospital in Delhi NCR. Check doctor list, patient reviews and feedback, consultation charges, address, contact number of top retroperitoneoscopic simple nephrectomy hospitals in Delhi NCR. Book appointment online and get upto 25% off on OPD fee.

TY - JOUR. T1 - Unclamped hand-assisted laparoscopic partial nephrectomy for predominantly endophytic renal tumors. AU - Engel, Jason D.. AU - Williams, Stephen B.. PY - 2013/5/7. Y1 - 2013/5/7. N2 - Purpose: To describe our initial experience with undamped laparoscopic hand-assisted partial nephrectomy for predominantly endophytic renal masses in the setting of relative contraindication to warm ischemia. Materials and Methods: Undamped laparoscopic hand-assisted partial nephrectomy was performed on eight consecutive patients from June 2009 to March 2010. All patients had predominantly endophytic renal masses with a preferential enhancing rim noted on the pre-operative computed tomography. The undamped hand-assisted approach was utilized for no warm ischemia, minimal blood loss, and enhanced visualization of the tumor bed with improved operative exposure. Results: Mean age of the participants was 55.8 years. All patients underwent undamped hand-assisted partial nephrectomy (le, zero ischemia). ...

TY - JOUR. T1 - Laparoscopic partial nephrectomy using microwave tissue coagulator for small renal tumors. T2 - Usefulness and complications. AU - Terai, Akito. AU - Ito, Noriyuki. AU - Yoshimura, Koji. AU - Ichioka, Kentaro. AU - Kamoto, Toshiyuki. AU - Arai, Yoichi. AU - Ogawa, Osamu. PY - 2004/6. Y1 - 2004/6. N2 - Objectives: We evaluated the usefulness and complications of laparoscopic partial nephrectomy for small renal tumors using a microwave tissue coagulator without renal pedicle clamping. Methods: Between September 1999 and March 2003, 19 patients with small renal tumors 11 to 45 mm in diameter underwent laparoscopic partial nephrectomy without renal ischemia. Results: Six and 13 patients were treated by the transperitoneal and retroperitoneal approaches, respectively. Excluding a case with open conversion due to dense perirenal adhesions, 18 patients successfully underwent laparoscopic procedures. The mean operative time was 240 minutes with minimal blood loss in 14 patients and 100 ...

Surgical Procedures of Hand-Assisted Laparoscopic Partial Nephrectomy on orangecountysurgeons.org A minimally invasive procedure, hand-assisted laparoscopic partial nephrectomy involves the removal of part of a diseased kidney. To perform the procedure, laparoscopic instruments and the surgeons hand are inserted through the abdominal cavity through two small incisions and one larger incision. This approach is optimized for kidney tumors that range from three to ten centimeters in diameter.

BACKGROUND: There are scant data on patient safety and the national diffusion of surgical innovations. Laparoscopic partial nephrectomy (LPN) provides an apt model for population-based analyses of patient safety and the propagation of complex surgical innovations.. METHODS: In the nationwide inpatient sample, we identified patients undergoing partial nephrectomy for renal tumors from 1998 to 2009 and utilized patient safety indicators (PSI) to measure preventable adverse outcomes.. RESULTS: Of the cases, 68,713 (87 %) were OPN and 9,842 (13 %) were LPN. The prevalence of LPN increased more than threefold from 2006 to 2009. Compared to open partial nephrectomy (OPN), LPN patients were more likely to be younger (p = 0.022), have lower Charlson comorbidity scores (p = 0.002), and undergo surgery at urban (p , 0.001) and teaching (p = 0.02) hospitals. On multivariate analysis, LPN was associated with a 28 % decreased probability of any PSI (adjusted odds ratio [ORadj] 0.72, 95 % confidence interval ...

Robotic partial nephrectomy using the DaVinci® robotic system can be a beneficial alternative for surgical patients with kidney cancer. This surgical procedure provides results that are similar to traditional laparoscopic surgery and open tissue trauma. It reduces the risk of infection, provides for less visible scars and provides the potential for faster recovery from surgery.. Robotic Partial Nephrectomy can provide all the advantages of the minimally invasive procedure with improved accuracy in excising the tumor and provide a shorter time the kidney is not receiving blood. ...

INTRODUCTION. The FDA approved da Vinci SP (Intuitive Surgical, Sunnyvale, CA) surgical system was developed specifically to facilitate single-site surgery, with the ideal aim to further reduce the invasiveness. We aimed to describe the technique of pure single-site trans-peritoneal robotic partial nephrectomy using the novel da Vinci SP surgical system.. METHODS. Three consecutive patients who were diagnosed with contrast-enhanced renal masses amenable of partial nephrectomy were counseled and accepted to undergo robot-assisted partial nephrectomy performed by using the SP Surgical System. Data collection received institutional review board approval (IRB 13-780). Subjects were provided with informed consent explaining the adoption of the novel surgical platform. The procedures were performed by reproducing the steps of the standard institutional multi-arms robotic approach to partial nephrectomy.. RESULTS. The surgeries were successfully performed. There was no need for conversion to standard ...

Purpose To determine the impact of transplant nephrectomy on morbidity and mortality and HLA immunization. Methods All patients who underwent transplant nephrectomy in our centre between 2000 and 2016 were included in this study. A total of 2822 renal transplantations and 180 transplant nephrectomies were performed during this period. Results The indications for transplant nephrectomy were graft intolerance syndrome: 47.2%, sepsis: 22.2%, vascular thrombosis: 15.5%, tumour: 8.3% and other 6.8%. Transplant nephrectomies were performed via an intracapsular approach in 61.7% of cases. The blood transfusion rate was 50%, the morbidity rate was 38% and the mortality rate was 3%. Transplant nephrectomies more than 12 months after renal transplant failure were associated with more complications (p = 0.006). Transfusions in the context of transplant nephrectomy had no significant impact on alloimmunization. Conclusion The risk of bleeding, and therefore of transfusion, constitutes the major challenge of this

In the previous study, serial section analysis in the Adriamycin animal model of progressive glomerulosclerosis, diffuse, rather than focal glomerulosclerosis were reported. However, the study in patients with nephrotic syndrome and idiopathic focal segmental glomerulosclerosis by three-dimensional analysis demonstrated a focal pattern of sclerosis. The distribution of lesions, whether focal or diffuse, has important implications, not only for pathogenesis and potential therapeutic response, but also for relevance of animal studies to human disease. We therefore evaluated the distribution of segmental glomerulosclerosis in the rat remnant kidney model. We used male M nich-Wistar rats weighing 250 grams at the start of the experiments. Ten rats had 1-1/2 nephrectomy. At the 24th week after the surgical procedure, GFR and arterial BP were measured. Renal tissues were then perfused with 1% glutaraldehyde at physiologic pressures. Sixty serial sections(4 micrometer thick) per a rat were stained with ...

TY - JOUR. T1 - Three-dimensional Printing and Augmented Reality. T2 - Enhanced Precision for Robotic Assisted Partial Nephrectomy. AU - Wake, Nicole. AU - Bjurlin, Marc A.. AU - Rostami, Pooya. AU - Chandarana, Hersh. AU - Huang, William C.. PY - 2018/6/1. Y1 - 2018/6/1. N2 - OBJECTIVE: To describe novel 3-dimensional (3D) printing and augmented reality (AR) methods of image data visualization to facilitate anatomic understanding and to assist with surgical planning and decision-making during robotic partial nephrectomy. MATERIALS AND METHODS: We created a video of the workflow for creating 3D printed and AR kidney models along with their application to robotic partial nephrectomy. Key steps in their development are (1) radiology examination (magnetic resonance imaging and computed tomography), (2) image segmentation, (3) preparing for 3D printing or AR, and (4) printing the model or deploying the model to the AR device. RESULTS: We demonstrate the workflow and utility of 3D printing and AR ...

TY - JOUR. T1 - Robotic laparoendoscopic single-site transumbilical partial nephrectomy. T2 - Functional and oncologic outcomes at 2 years. AU - Tiu, Albert. AU - Shin, Tae Y.. AU - Kim, Kwang H.. AU - Lim, Sey K.. AU - Han, Woong K.. AU - Rha, Koon H.. N1 - Funding Information: Funding Support: This study was supported by a faculty research grant of Yonsei University College of Medicine for 2012 ( 6-2012-0181 ). PY - 2013/9. Y1 - 2013/9. N2 - Objective To assess the functional and oncologic outcomes of robotic laparoendoscopic single site surgery (LESS) partial nephrectomy with a minimum of 2-year follow-up. Materials and Methods Thirty-nine consecutive patients who had undergone robotic LESS partial nephrectomy were identified with a minimum of 2-year follow-up. Perioperative data were recorded along with functional and oncologic outcomes. Patients estimated glomerular filtration rate was determined using the Modification of Diet in Renal Disease formula. A univariate analysis was performed ...

近腎門之腎臟腫瘤：機械手臂輔助下部分腎切除之強化精準度 方琬云、 郭謹瑋、蔡秉浩、王百孚 彰化基督教醫院 外科部 泌尿科 When Renal Tumor Close to Hilum: The Enhanced Accuracy of Partial Nephrectomy by Robotic Assistance Wan-Yun Fang, Chin-Wei Kuo, Ping-Hao Tsai, Pai-Fu Wang Division of Urology, Department of Surgery, Changhua Christian Hospital, Taiwan Introduction When renal hilar tumor was encountered, the surgery would become challenging. With refined instrument and devices, the morbidity could be reduced by enhanced accuracy of dissection, resection, and reconstruction. We demonstrated a delicate and prompt procedure of partial nephrectomy by robotic assistance or renal hilar tumor. Case presentation A 55-year-old male, who had left renal tumor found near to hilum, had received robotic-assisted partial nephrectomy. The nephrometry score was 7p. The whole procedure was smooth and delicate especially during tumor dissection and suturing the rough

PURPOSE: To evaluate a fast method to identify renal vessels during retroperitoneal laparoscopic nephrectomy. METHODS: One hundred fifty retroperitoneal laparoscopic nephrectomies were performed from October 2003 to June 2006. The renal arteries were

16 January 2017. Maximum safety for patients with kidney cancer.. A partial nephrectomy procedure using the da Vinci® robotic system in combination with high-resolution laparoscopic intraoperative ultrasound offer significant benefits to patients suffering from kidney cancer.. In the last 6 years, a multitude of robot-assisted partial nephrectomy procedures have been performed at HYGEIA Hospital with the aid of laparoscopic intraoperative ultrasound and the contribution of the Hospitals Ultrasound Department.. As noted by Dr. Emanuel Panagiotou, Director of the HYGEIA Hospital 2nd Urology Clinic, Nowadays, for tumors measuring 5, 6 or even 7 centimeters, only the tumor is removed (partial nephrectomy) and the rest of the organ (kidney) is preserved. The magnification is 15-20 times greater, allowing for finer robotic arm movements and resection of small or larger tumors on healthy margins. In the case of partially exophytic or completely endophytic (enclosed inside the kidney) renal tumors, ...

TY - JOUR. T1 - Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. AU - Chen, Jiankang. AU - Chen, Jianchun. AU - Neilson, Eric G.. AU - Harris, Raymond C.. PY - 2005/12/9. Y1 - 2005/12/9. N2 - Loss of functioning nephrons stimulates the growth of residual kidney tissue to augment work capacity and maintain normal renal function. This growth largely occurs by hypertrophy rather than from hyperplasia of the remaining nephrons. The signaling mechanisms that increase RNA and protein synthesis during compensatory renal hypertrophy are unknown. This study found that the remaining kidney hypertrophied 42% by 16 d after unilateral nephrectomy (UNX) in DBA/2 mice. Immunoblotting analysis revealed increased phosphorylation of the 40S ribosomal protein S6 (rpS6) and the eukaryotic translation initiation factor (eIF) 4E-binding protein 1 (4E-BP1), the two downstream effectors of the mammalian target of rapamycin (mTOR). The highly specific mTOR inhibitor rapamycin blocked ...

Introduction: Laparoendoscopic single-site donor nephrectomy (LESS-DN) emerged as an advancement to standard laparoscopic surgery with its advantage of using a single small incision concealed in the umbilical scar as the operative as well as extraction port. LESS-DN can reduce donor morbidity and improve donor satisfaction with better cosmetic results. Aim: To present our experience with trans-umbilical LESS DN. Methods: retrospective study of data from 110 consecutive LESS DN donors and their recipients. Standard laparoscopic instruments were used in all patients. All cases had left sided nephrectomy and no exclusion criteria were used.Results: From 05/2015 to 11/2016, 110 LESS DN were performed by a single surgeon. The mean operative time was 175.9 ± 24.9 minutes and the mean warm ischemia time was 5.2± 1.02 mins. Mean body mass index was 24.8 ± 4.5 kg/m2. Complex vascular anatomy (multiple arteries/veins or retro-aortic vein) was found in 40 patients (36.3%). Pure LESS-DN was successfully ...

Looking for online definition of lumbar nephrectomy in the Medical Dictionary? lumbar nephrectomy explanation free. What is lumbar nephrectomy? Meaning of lumbar nephrectomy medical term. What does lumbar nephrectomy mean?

TY - JOUR. T1 - Risk factors and prevention of rhabdomyolysis after laparoscopic nephrectomy. AU - Shaikh, Shafaque. AU - Nabi, Ghulam. AU - McClinton, Sam. PY - 2006/11. Y1 - 2006/11. KW - BMI. KW - Laparoscopic nephrectomy. KW - Pressure points. KW - Rhabdomyolysis. UR - http://www.scopus.com/inward/record.url?scp=33749563081&partnerID=8YFLogxK. U2 - 10.1111/j.1464-410X.2006.06454.x. DO - 10.1111/j.1464-410X.2006.06454.x. M3 - Article. C2 - 17034598. AN - SCOPUS:33749563081. VL - 98. SP - 960. EP - 962. JO - BJU International. JF - BJU International. SN - 1464-4096. IS - 5. ER - ...

The 2 previous studies on the impact of nephrectomy (EORTC, SWOG) in metastatic renal cell carcinoma have justified recommendation to initial nephrectomy for patients presenting with metastatic renal cell carcinoma. But these studies were performed at the time of immunotherapy.. The objective is Evaluation of the importance of nephrectomy in patients with metastatic renal cell carcinoma treated with sunitinib (AA) Arm A : Nephrectomy followed by Sunitinib Arm B : Sunitinib alone Sunitinib will be administrated orally daily for 4 weeks followed by a 2 week rest( schedule 4/2), 6 weeks are considered as a cycle The starting dose will be 50 mg daily with provision for dose reduction based on tolerability Patient will be treated until disease progression or unacceptable toxicity occurrence or withdraw. ...

Friedersdorff, F., Werthemann, P., Cash, H., Kempkensteffen, C., Magheli, A., Hinz, S., Waiser, J., Liefeldt, L., Miller, K., Deger, S. and Fuller, T. F. (2013), Outcomes after laparoscopic living donor nephrectomy: comparison of two laparoscopic surgeons with different levels of expertise. BJU International, 111: 95-100. doi: 10.1111/j.1464-410X.2012.11348.x ...

We studied the source of inactive renin in plasma by investigating the changes of active and inactive renin after bilateral nephrectomy in the rat. Active renin rapidly decreased after bilateral nephrectomy, with a half-life of approximately 15 minutes. Inactive renin, on the other hand, was 20.96 +/- 1.63 ng/ml/hr before nephrectomy and gradually increased to reach a peak at 20 hours after nephrectomy (193 +/- 62 ng/ml/hr). The molecular weight of active renin was approximately 40,000 and that of inactive renin was approximately 60,000 on a Sephacryl S-200 column. Inactive renin was separated from active renin by a Cibacron blue column, and the 0 time inactive renin eluted in the same fractions as the inactive renin from 20 hours after nephrectomy. The pH optimum of inactive renin in rat renin substrate was between 5.5 and 7.5, which differs from the optimal value of pepsin or cathepsin D. The increase of inactive renin in nephrectomized rats was not prevented by removal of the salivary glands, ...

Male F1 New Zealand Black X New Zealand White mice, which spontaneously develop immune complex renal disease, underwent unilateral nephrectomy at 3 months of age and were compared with sham-operated controls. At 12 months of age only 24% of mice with a single kidney were alive, while 85% of sham-operated controls survived to the same age. Unilaterally nephrectomized mice had more severe renal histologic changes, as shown by light and immunofluorescence microscopy. ...

SAN FRANCISCO-The length of time from nephrectomy up until the diagnosis of metastatis has been confirmed as prognostic for patients whose renal cell carcinoma was treated with targeted therapies - just as it is in patients overall - according to a retrospective analysis reported to the ASCO Genitourinary Symposium by Professor Giuseppe Procopio, who is a clinical researcher specializing in medical therapies for genitourinary cancers at the Istituto Nazionale dei Tumori in Milan. In his presentation, however, he highlighted the need for randomized controlled studies to determine the effects of nephrectomy on the disease process. He explained that currently it is unclear whether surgery is causative of a good outlook or whether patients whose metastases emerged later have more benign disease than those whose disease becomes metastatic sooner.. CONTACT ...

Question - Is there any other treatment option other than radical nephrectomy for renal cell carcinoma?. Ask a Doctor about diagnosis, treatment and medication for Renal cell carcinoma, Ask a Urologist

Introduction Laparoscopic nephrectomy (LN) was first performed by Clayman et al in 1991 and has since become a standard therapy for various renal lesions. LN may be performed by a transperitoneal or retroperitoneal approach for the treatment of both benign and malignant conditions.

RESULTS: A total of 40 patients underwent Radical Nephrectomy (RN) with IVC tumor thrombus. Open and robotic surgery represented respectively 30 and 10 cases. The two groups were comparable regarding pre-operative tumor and patient characteristics. Robotic procedures were associated with lower Estimated Blood Loss (EBL) (500 vs. 1250mL, p = 0.02), shorter Intensive Care Unit stay (2 vs. 4 days, p = 0.03) and decrease of global Length Of Stay (LOS) (7 vs. 10 days, p < 0.01). Operative Time (OT) was significantly longer in the robotic group (350.5 vs. 208 min, p < 0.01). No difference were observed between the two approaches regarding complications and oncological outcomes ...

Chronic pyelonephritis resulting from a mixed infection was produced in rats. They displayed marked hyposthenuria and azotemia and, on pathologic examination at the end of one year, revealed severe contraction and scarring of the kidneys. Hypertensive vascular disease did not develop even in rats with unilateral nephrectomy, although some animals succumbed to renal failure. The results indicate that parenchymal renal injury from chronic renal infection, even when it results from mixed infection and is associated with a decrease in renal mass, does not result in hypertensive disease. It is suggested that this is due to the absence of a vascular lesion producing renal ischemia.. ...

Glove-Assisted Laparoscopic Radical Nephrectomy: A Novel Technique. Nozaki, Tetsuo; Asao, Yoshihiro; Ichimatsu, Keisuke; Ito, Takatoshi; Yasuda, Kenji; Watanabe, Akihiko; Komiya, Akira; Fuse, Hideki // Journal of Laparoendoscopic & Advanced Surgical Techniques;Dec2010, Vol. 20 Issue 10, p843 Background: Laparoscopic surgery has not yet met with widespread acceptance due to its degree of technical difficulty. The laparoscopic radical nephrectomy procedure was improved with the aid of an abdominal wall sealing device, a wound retractor, and a surgical glove. Methods: A 5 cm skin... ...

Place : RF/ MED 176. TelePresence : AH Deans Room / KUH 9th Meeting Room. ********************************************************************. Zero ischemia robotic partial nephrectomy. Renal cell carcinoma (RCC), accounts for 2-3% of all malignant neoplasms in adults. Currently, the widespread use of radiological imaging modalities led the detection of most renal tumors incidentally, as small renal masses in asymptomatic patients [1]. The curative treatment of renal tumors is radical nephrectomy (RN), however, partial nephrectomy (PN) has become the standard option in tumors less than 4 cm, and in tumors between 4-7 cm, if suitable [2]. Previously, it has been reported that, PN had similar oncologic outcomes with favorable functional outcomes compared with RN [3]. The relative inability of cooling the kidney during robotic and laparoscopic approaches, is still remaining as a challenging issue [4]. The introduction of the da Vinci surgical robotic system (Intuitive Surgical Sunnyvale, CA, USA) ...

Kidney cancer (renal cell cancer) | Laparoscopic nephrectomy with ureterectomy. Urology: Treatment in Bern, Switzerland ✈. Prices on BookingHealth.com - booking treatment online!

Introduction: Robot-assisted partial nephrectomy (RAPN) is an established, minimally invasive technique to treat patients with renal masses. The aim of this study was to assess the learning curve (LC) of RAPN, evaluate its impact on perioperative outcomes following RAPN and to study the role of surgeon experience in achieving

Laparoscopic nephrectomy for wilms tumor after chemiotherapy: our initial experience/MG. SCUDERI; A. DI CATALDO; L. VIRARDI; M. FALSAPERLA; A. DI BENEDETTO; DI BENEDETTO V.-(2008), pp. 101-101.((Intervento presentato al convegno 17th ipegs annual congress for endosurgery in children tenutosi a cannes francia nel 12-14 giugno 2008 ...

Objective: In this study, we aimed to evaluate the presence and thickness of pseudocapsule after partial nephrectomy in renal cell carcinoma (RCC) cases. ...

Nephrosclerosis | Laparoscopic nephrectomy. Urology: Treatment in Aarau, Switzerland ✈. Prices on BookingHealth.com - booking treatment online!

Objetivo. Los casos de angiomiolipoma renal gigante (,9cm) son un reto terapéutico por su baja frecuencia y su tamaño. El objetivo del tratamiento de los pacientes con angiomiolipoma renal debe ser la extirpación completa del tumor, con una técnica quirúrgica conservadora de nefronas, sin complicaciones y mediante un abordaje mínimamente invasivo.. Material y métodos. Presentamos 3 casos de angiomiolipoma gigante (14, 12 y 10cm) tratados mediante abordaje combinado: embolización supraselectiva y posterior nefrectomía parcial laparoscópica, en 3 hospitales diferentes.. Resultados. Ningún caso precisó reconversión a cirugía abierta, en uno de los 3 pacientes se realizó clampaje arterial y ninguno experimentó complicaciones.. Conclusiones. El abordaje combinado permite una cirugía con criterios de mínima invasión, conservadora de nefronas, con escaso sangrado y disminución del tiempo de isquemia caliente.. ...