Introduction: Mixed adenoneuroendocrine carcinomas of the gastrointestinal tract are rare neoplasms. In the 2000 WHO classification of endocrine tumors, such neoplasms were defined as mixed exocrine-endocrine tumors when each component represents at least 30% of the lesion. In the most recent WHO classification, such neoplasms are called "mixed adenoneuroendocrine carcinomas" (MANECs). They are a challenge for the diagnostic and treatment ...
The Roux-en-Y gastric bypass is one of the most common procedures currently performed for surgical treatment of patients with severe obesity. Gastric cancer after bariatric surgery is not common, with most of them arising in the excluded stomach. Gastric mixed adenoneuroendocrine carcinomas are a rare type of stomach malignancy, composed of both adenocarcinoma and neuroendocrine tumor-cell components, with the latter comprising at least 30% of the whole neoplasm. In this article, we report a unique case of a mixed adenoneuroendocrine carcinoma with a mixed adenocarcinoma (tubular and poorly cohesive) component arising in the gastric pouch of a patient who underwent previous Roux-en-Y gastric bypass for glycemic control ...
TY - JOUR. T1 - Metaplastic breast cancer has a poor response to neoadjuvant systemic therapy. AU - Al-Hilli, Zahraa. AU - Choong, Grace. AU - Keeney, Michael G.. AU - Visscher, Daniel W. AU - Ingle, James N.. AU - Goetz, Matthew Philip. AU - Jakub, James W. PY - 2019/8/15. Y1 - 2019/8/15. N2 - Objective: Metaplastic breast cancer (MetaBC) is a rare breast cancer subtype poorly responsive to systemic therapy in the metastatic setting with high recurrence rates in the adjuvant setting. However, limited data exist regarding response to neoadjuvant chemotherapy (NAC). We performed a single institutional study to assess the clinical and pathological complete response rates (pCR) of MetaBC to NAC. Methods: Mayo Clinic Rochester patients with MetaBC treated with NAC were identified using the institutional medical index. Patient demographics, tumor characteristics, chemotherapy treatment, clinical and pathological response, and long-term outcomes were reviewed. Pathologic response was assessed by ...
TY - JOUR. T1 - Gastric neuroendocrine neoplasms and related precursor lesions. AU - La Rosa, Stefano. AU - Vanoli, Alessandro. PY - 2015. Y1 - 2015. N2 - Gastric neuroendocrine neoplasms (NENs) are a heterogeneous group of tumours showing different clinicopathological features and behaviour, implying a wide spectrum of therapeutic options. They are currently classified using the 2010 WHO classification of digestive neuroendocrine neoplasms into G1-neuroendocrine tumours (NETs), G2-NETs, neuroendocrine carcinomas (NECs) and mixed adenoneuroendocrine carcinomas (MANECs). However, most gastric NENs are composed of ECL-cells (ECL-cell NETs) that can be preceded by ECL-cell hyperplastic and dysplastic lesions, whose oncologic potential has not yet been completely elucidated. ECL-cell NETs differ considerably in terms of prognosis depending on the proliferative status and clinicopathological background. The integration of both aspects in the diagnostic pathway may help to better classify tumours in ...
Background: Metaplastic breast cancer (BC) is a treatment-refractory rare type of BC with characteristics similar to claudin-low tumors. Understanding the genomic landscape of metaplastic BC can lead to identification of new therapies.. Methods: Patients with metastatic metaplastic BC referred for experimental therapies, who had adequate archival tumor tissue for DNA extraction, had targeted next-generation sequencing (NGS) for 3,769 exons of 236 cancer-related genes and 47 introns from 19 genes to an average depth of 1000X using the Illumina HiSeq 2000 platform (Foundation One, Foundation Medicine, MA).. Results: NGS results were obtained for 10 women with metaplastic BC (median age 60 years [39-73], median prior therapies for metastatic BC 0 [0-1]). NGS revealed a total of 41 aberrations in 25 genes and all 10 patients had at least 1 molecular aberration (range 1-7, median 4). Of 41 detected molecular aberrations, 17 (41%) included putative activation of the PI3K/mTOR and/or MAPK pathways ...
Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority are benign, but some can be malignant. They are most frequently found incidentally on pelvic examination or at laparotomy. Brenner tumours very rarely can occur in other locations, including the testes. On gross pathological examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral (arising in one ovary, the other is unaffected). The tumours can vary in size from less than 1 centimetre (0.39 in) to 30 centimetres (12 in). Borderline and malignant Brenner tumours are possible but each are rare. Histologically, there are nests of transitional epithelial (urothelial) cells with longitudinal nuclear grooves (coffee bean nuclei) lying in abundant fibrous stroma. Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, ...
A 58 year old woman presented for evaluation of a painless swelling anterior to lower half of sternum. Physical examination revealed a non-tender swelling of size 6×8cm in the presternal location in between the two breasts. The characteristic punctum over the lesion made the diagnosis of epidermal cyst straightforward. This was a giant epidermal cyst, as epidermal cysts usually do not exceed 5cm in diameter. The patient underwent complete excision of the lesion, which on histopathologic examination was confirmed to be epidermal cyst.. ...
The findings of a clinicopathological and biochemical study of epidermal cysts and a review of the relevant literature are presented. A punctum was found in 40% of 34 epidermal cysts that were studied in detail. The findings of the histological study were in favour of the punctum being the orifice of an obstructed hair follicle from which at least a proportion of the epidermal cysts are likely to develop. The biochemical analysis of the contents of the cysts revealed a very low protein and lipid content, thus ruling out any "sebaceous contribution. Bacteriological study of clinically inflamed cysts showed that inflammation in these lesions was usually aseptic unless there was a communication between the cyst cavity and the exterior.. ...
There are many sites that provide pictures of epidermal cysts such as Dermnet.com, MedicineNet.com, Skinsight.com, EverydayHealth.com and DermNetNZ.org. Epidermal cysts appear on different parts of...
On gross pathological examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral (arising in one ovary, the other is unaffected). The tumours can vary in size from less than 1 centimetre (0.39 in) to 30 centimetres (12 in). Borderline and malignant Brenner tumours are possible but each are rare. ...
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Hybrid PNSTs were initially described by Feany et al. in 1998 [3] in nine patients, most of which were adults. The tumor showed components of neurofibroma and schwannoma in the same tumor. Of those cases, 2 cases were dermal and subcutaneous, while 5 were subfascial. They suggested that the presence of schwannoma and neurofibroma components together in one tumor meant that in spite of definite clinicopathologic differences, the two entities were even more closely related than was earlier thought. Zamecnik in his comment on Feanys study called these hybrid tumors "a conceptual challenge" [13]. In 2004, Michal et al. [8] reported 6 hybrid tumors which were combinations of schwannoma and perineurioma. Out of 6 cases, five occurred on the digits and 5 were in adult females. Their cases demonstrated the classic IHC stain profile of S100+/CD34, EMA- in the schwannomatous and the S100- /CD34 and EMA+ in the perineuromatous areas. In 2005, Kazakov et al. reported 3 extradigital cases, two females and ...
An epidermal cyst is a common benign subcutaneous tumor and rarely develops malignancy. We report a case of an undifferentiated cutaneous squamous cell carcinoma (SCC) that arose from an epidermal cyst on the left side of the neck. The epidermal cyst had rapidly increased in size and presented cauliflower-like tumor. Histological study revealed undifferentiated squamous cell carcinoma that was arising from the epidermal cyst.
Primary signet-ring cell carcinoma of the urinary bladder is a rare variant of mucus-producing adenocarcinoma constituting approximately 0.5% to 2.0% of all primary carcinomas of the bladder. This tumor initially presents as a high-grade, high-stage lesion and diffusely invades the bladder wall without forming intraluminal growth. The patients have no specific symptoms, which leads to delayed diagnosis and poor prognosis. We report the case of a 51-year-old Moroccan Berber man consulting for gross hematuria. Ultrasonography and a computed tomography scan found a bladder tumor diffusely invading the bladder wall. A histopathological examination of the tumor chips from a transurethral resection of the bladder revealed signet-ring cell adenocarcinoma. The gastrointestinal tract exploration did not reveal any other tumor localization. A radical cystectomy and adjuvant cisplatin and gemcitabine chemotherapy were therefore performed resulting in 18 months of survival without metastasis and a good quality of
A case of signet-ring cell lymphoma affecting bone marrow is reported. The tumour presented as multiple lytic lesions in the lumbosacral spine. A bone biopsy specimen showed the typical appearances of signet-ring cell lymphoma, and the cells stained positively with antiserum to CD20, though neither immunoglobulin light or heavy chains could be shown within the vacuoles. The patient subsequently responded to chemotherapy.. ...
Gynecology: Brenner tumor | Surgery. Treatment in Fribourg, Switzerland ✈ Find the best medical programs at BookingHealth - ✔Compare the prices ✔Online booking.
TY - JOUR. T1 - Signet-ring cell basal cell carcinoma. AU - Roh, Mi Ryung. AU - Kwon, Ji Eun. AU - Lee, Kwang Gil. AU - Lee, Ju Hee. PY - 2010/11/1. Y1 - 2010/11/1. UR - http://www.scopus.com/inward/record.url?scp=77956795588&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=77956795588&partnerID=8YFLogxK. U2 - 10.1111/j.1600-0560.2010.01581.x. DO - 10.1111/j.1600-0560.2010.01581.x. M3 - Article. C2 - 20626471. AN - SCOPUS:77956795588. VL - 37. SP - 1188. EP - 1189. JO - Journal of Cutaneous Pathology. JF - Journal of Cutaneous Pathology. SN - 0303-6987. IS - 11. ER - ...
Braun KP, Kappelle LJ, Kirkham FJ, Deveber G. Diagnostic pitfalls in paediatric ischaemic stroke. Dev Med Child Neurol. 2006 Dec; 48(12):985-90 ...
Harvard University Center for the EnvironmentSchool of Engineering and Applied Sciences Office: Pierce Hall, 313Assistant: LaShanda Banks, (617) 496-1461Email: [email protected]: https://seas.harvard.edu/brenner/Contact.html
Free Online Library: Pilomatricoma.(Case study) by Applied Radiology; Health, general Epithelial tumors Care and treatment Case studies Diagnosis Patient outcomes Risk factors
Purchase Pocket Companion to Brenner and Rectors The Kidney - 2nd Edition. Print Book & E-Book. ISBN 9781416066408, 9781455703784
Purchase Pocket Companion to Brenner and Rectors The Kidney - 2nd Edition. Print Book & E-Book. ISBN 9781416066408, 9781455703784
Im surprised it took six comments to get it right, but I was eating at brunch at Max Brenner near Union Square. The dish: the...
One of my doctors saw a patient for UTI/Dysuria. Due to other complaints, he performed a vaginal exam and found a epidermal cyst. He feels
Oil Free: Yes. Maximum Pumping Speed: 31.2 L/min. Ultimate Pressure: 0.004 mbar. Noise Levels: Vacuum--62dB @ 3' ( 914 mm ) max vacuum. Pressure Pump--63 dB @ 3' ( 914 mm ). Weight: 20 Lbs.
A Free portal for dental pg aspirants,BDS graduates. High Yield Points, Strategies with respect to the Indian Medical Post Graduate PG Entrance Exams like AIIMS,AIPG, JIPMER, CMC Vellore, PGI Chandigarh, UPSC, TNPSC, State PG Exams like Delhi PG, UPPG, Tamilnadu PG (TNPG), Karnataka PG etc.
Staring at the odd-looking bumps under your skin? You may be suffering from Sebaceous or Epidermal cysts, a medical condition that gives an abnormal appearance to your skin. What is a Sebaceous Cyst? Picture 1 - Sebaceous Cyst Source - photobucket Sebaceous Cysts, sometimes misspelled as Sebacous Cysts, are firm, dome
Mixed tumors of mesodermal origin, polypoid in form, often termed grapelike sarcomas, and malignant in character, are found in the vagina and also in the uterin
Learn about the causes, symptoms, diagnosis & treatment of Benign Gynecologic Lesions from the Professional Version of the Merck Manuals.
99.5 WMAG-FM will broadcast a two-day radiothon to benefit Brenner Childrens Hospital at Wake Forest Baptist Medical Center on Thursday and Friday, Dec. 6-7.
Learn about the Brenner Labs research focus in the Division of Rheumatology, Immunology and Allergy at Brigham and Womens Hospital.
... 14,5 cm Füllmenge: ca. 1,5 Liter Material : Stahl Farbe(n): Weiß Gewicht: ca. Diese Kamine unterliegen nicht der Feuerstättenverordnung! Einfach aufhängen, Brenngel oder geruchsneutralen Bioalkohol einfüllen, anzünden - fertig und geniessen! Wandkamin in edlem und modernen Look! In Kombination mit den beruhigenden Flammen wirkt er überaus elegant und stylisch! Lieferumfang: Gelkamin, Montagematerial (Schraubern, Dübel und Wandabstandhalter), Edelstahlbrennboxen, Flammenlöscher. Grillplatte Wendeplatte Gusseisen Pizzaplatte für Gasgrill Massiv. Türvorhang Insektenschutz Vorhang Tür Fliegengitter Streifenvo.. 8 Liter Getränkespender mit Hahn Dispenser Zapfhahn Zapfsäule.. 3 x Feuerzeug biegsam flexibel Gas XXL Stabfeuerzeug 27 cm lan.. Moderne Feuerschale Gussstein Ø 39,5cm Schwarz/Grau. Gewürzstreuer Gewürzglas Edelstahl Vorratsgläser Salzstreuer G.. Ø 36,5 cm Aluminium Dekoschale Alu Schale ...
Sarcoidosis (SA) is accompanied by malignancy more than can be explained by chance. Cancer can occur in patients with an established diagnosis of SA and SA can subsequently develop in a cancer patient
Primary nodal follicular lymphoma with spindle cell features: a potential diagnostic pitfall (pages 120-122). D G-S Lim, M-E Nga, L H-C Tan, S-B Ng, S-L Tien, A S T Lim, A R Chang and T P Thamboo. Version of Record online: 28 JUN 2008 , DOI: 10.1111/j.1365-2559.2008.03056.x. ...
Manchineel Poisoning Bradyarrhythmia A Possible Association. The following article describes a unique case of manchineel poisoning in which a seemingly unknown side effect arose, brandyarrhythmia. - PR11946165
The selected wines from Five Clover wines are imported and supplied to you directly to your door.. All our wines can only be bought in 6 or 12 bottles per case. You may pick and mix your selection to make up your unique case of wines.. ...
The selected wines from Five Clover wines are imported and supplied to you directly to your door.. All our wines can only be bought in 6 or 12 bottles per case. You may pick and mix your selection to make up your unique case of wines.. ...
Sean Brenner The forecast for California forced the UCLA economists to reconsider the data sources whose patterns typically inform economic...
TY - JOUR. T1 - Malignant Brenner tumor mimicking a primary squamous cell carcinoma of the cervix. AU - Badve, Sunil. AU - Fehmian, C.. AU - Cass, I.. AU - Goldberg, G. L.. AU - Jones, J. G.. PY - 1999/9. Y1 - 1999/9. N2 - An 86-year-old female presented with a necrotic cervical mass that was biopsy-proven squamous cell carcinoma. She had an elevated CA-125 and a pelvic mass. At surgery, this mass was found to be of adnexal origin and contiguous with the cervix. Histology showed a malignant Brenner tumor with abundant squamous differentiation eroding the cervix and simulating a primary cervical malignancy. We describe this case and review the literature on metastatic tumors to the cervix.. AB - An 86-year-old female presented with a necrotic cervical mass that was biopsy-proven squamous cell carcinoma. She had an elevated CA-125 and a pelvic mass. At surgery, this mass was found to be of adnexal origin and contiguous with the cervix. Histology showed a malignant Brenner tumor with abundant ...
Urogenital system development in mammals requires the coordinated differentiation of two distinct tissues, the ductal epithelium and the nephrogenic mesenchyme, both derived from the intermediate mesoderm of the early embryo. The former give rise to the genital tracts, ureters and kidney collecting duct system, whereas mesenchymal components undergo epithelial transformation to form nephrons in both the mesonephric (embryonic) and metanephric (definitive) kidney. Pax-2 is a transcriptional regulator of the paired-box family and is widely expressed during the development of both ductal and mesenchymal components of the urogenital system. We report here that Pax-2 homozygous mutant newborn mice lack kidneys, ureters and genital tracts. We attribute these defects to dysgenesis of both ductal and mesenchymal components of the developing urogenital system. The Wolffian and Mullerian ducts, precursors of male and female genital tracts, respectively, develop only partially and degenerate during ...
Meet Doctor Stephen Brenner. Here are his vitals: Hes board certified, specializing in Internal Medicine. Doctor Brenner is a highly experienced doctor, with 38 years of practice in the field Highly regarded by his patients they rate him 4 out of 4 stars. They point out the time he spends with them. He has won a number of awards, including Patients Choice Award 2010 and Compassionate Doctor Recognition 2010. Is affiliated with a highly rated hospital. Graduated from Upstate Medical University Physical Medicine and Rehabilitation. His average waiting time is 16 minutes. He accepts new patients. He has a number of insurance plans accepted. Use Vitals.com to examine Doctor Stephen D Brenner from New Haven, Connecticut. See patient comments make an appointment or even let us help you to prepare for your visit. Vitals .com where doctors are examined.. ...
Pleomorphic adenoma, also known as benign mixed tumor, is the most common tumor of salivary gland origin, accounting for about 60-70% of all salivary gland tumors (Peel and Seethala, 2007; Downer, et al., 2011; Papadogeorgakis ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
In this review, we outline the biology and management of patients with carcinosarcomas and related malignancies, which are often included under the broader concept of sarcomatoid carcinomas. Carcinosarcomas are unusual tumors that are commonly gynecologic in origin, where they are referred to as malignant mixed Müllerian tumors, but may appear in any anatomic site. Although a variety of hypotheses have been presented as to the biphasic nature of these tumors, carcinosarcomas seem to represent the best example in human cancers of the concept of epithelial-mesenchymal transition (EMT), in which the two parts of the tumor are genomically related to one another, as opposed to the mesenchymal component that represents a second neoplasm or (benign) reactive process ...
Cystic acne may be frustrating and painful, but it is treatable. Most cystic acne wont disappear overnight, but you can take steps to reduce it in a matter of weeks. Your dermatologist can offer creams, pills, and procedures that may offer dramatic results. A good daily skincare routine and healthy practices might also help. Scars can result from cystic acne, but these can be reduced through proper treatment. Keep in mind that while some people may see results quickly, others may need more time to heal.. Make an appointment with your dermatologist. The fastest and most effective way to fight cystic acne is through medical treatment from a dermatologist. Your dermatologist can prescribe the medications or perform non-invasive procedures.. ...
Adenolipoma refers to a variant of a lipoma with entrapped eccrine or, rarely, apocrine units. We present 5 cases of cutaneous adenolipoma to demonstrate the spectrum of changes in the lipomatous and epithelial components. The cases include 3 lesions
Brenner Childrens Hospital, the pediatric arm of Wake Forest Baptist Medical Center, is gaining new physicians and will be expanding and relocating its outpatient clinic in Lexington to a new location.
Visit Healthgrades for information on Dr. Gail Brenner, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
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