Third, some gonococci are able to engage in "conjugation," which is essentially bacteria sex! During conjugation, one bacterium uses an appendage called a sex pilus to attach to another bacterium and deliver a circular piece of DNA from the donor to the recipient. The recipient is now in possession of any traits its new DNA encodes.. You know how we humans are officially Homo sapiens? The scientific name for gonococci is Neisseria gonorrhoeae. And, just as we had genetic "cousins" in the form of Homo neanderthalensis (aka the Neanderthals), so too do Neisseria gonorrhoeae have cousins in the Neisseria genus. Most human-associated Neisseria species dont cause disease, and live peacefully in our upper respiratory tracts. These species include Neisseria flavescens, Neisseria flava, Neisseria perflava, Neisseria mucosa, Neisseria sicca, Neisseria polysaccharea, and more.. When gonococci meet their cousins at a family reunion, they dont swap recipes for potato salad - they swap genetic material. ...
Neisseria perflava ATCC ® 14799D-5™ Designation: Genomic DNA from Neisseria perflava strain 28 TypeStrain=False Application:
Curated}} {{Biorealm Genus}} [[Image:ng-lym1.jpg,thumb,250px,right,Neisseria gonorrhoeae. From [http://neisseria.org/ng/images/ Dr. Ian Boulton.]]] ==Classification== ===Higher order taxa:=== Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae ===Species:=== Neisseria animalis; N. bacilliformis; N. canis; N. cinerea; N. dentrificans; N. dentiae; N. elongata; N. flava; N. flavescens; [[N. gonorrhoeae]]; N. iguanae; N. lactamica; N. macacae; N. meningitidis; N. mucosa; Neisseria perflava; Neisseria pharyngis; Neisseria polysaccharea; N. sicca; N. subflava; N. weaveri; N. sp. {, , height="10" bgcolor="#FFDF95" align="center" , NCBI: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=482&lvl=3&lin=f&keep=1&srchmode=1&unlock Taxonomy] Genome: -,font size="2">[http://www.ncbi.nlm.nih.gov/genomes/framik.cgi?db=Genome&gi=155 Neisseria meningitidis MC58] -[http://www.ncbi.nlm.nih.gov/genomes/framik.cgi?db=Genome&gi=156 Neisseria meningitidis Z2491 ...
Author Summary Many bacteria are able to secrete toxins targeted against neighboring cells. In order to protect themselves against their own toxin, they also express an
Horizontal gene transfer is an important source of genetic variation among Neisseria species and has contributed to the spread of resistance to penicillin and sulfonamide drugs in the pathogen Neisseria meningitidis. Sulfonamide resistance in Neisseria meningitidis is mediated by altered chromosomal folP genes. At least some folP alleles conferring resistance have been horizontally acquired from other species, presumably from commensal Neisseriae. In this work, the DNA sequence surrounding folP in commensal Neisseria species was determined and compared to corresponding regions in pathogenic Neisseriae, in order to elucidate the potential for inter-species DNA transfer within this region ...
Genus Neisseria has a specie called Neisseria gonorhea or commonly called Gonococcus. It has a gram negative, kidney or bean shaped intracellular diplococcic. This is usually killed when outside of the human body. It is transmitted through sexual intercourse, with an infected partner via infected birth canal of infected mother during delivery; indirectly transmitted via contaminated hands, fomites contaminated with purulent discharges; directly also via oral sex.. Gonorrhea originated from the two Greek words: "gono" meaning semen and "rhein" which means flow. It is an acute, inflammatory and infectious disease o the mucus membrane of the genitor-urinary tracts of men and women as well as the eyes of the newborn due to N. Gonorrhoea. Its incubation period usually is 3-5 days after the contact with an infected partner. ...
1JG9: Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose.
The emergence of antibiotic-resistant gonorrhea is considered one of the most pressing problems in infectious disease - just two years ago, the Centers for Disease Control and Prevention named it an "urgent threat," and indeed, gonorrhea seems to be evolving resistance to drugs at quite a rapid clip. Gonococci can acquire resistance to antibiotics in three ways.. First, a genetic mutation can endow bacteria with special antibiotic-fighting powers, making it harder for a drug like penicillin to attach to their cells and destroy them. Such a mutant is more likely to gain evolutionary traction if it finds itself in an antibiotic-drenched environment in which resistance to that drug allows it to "outcompete" other bacteria. Indeed, antibiotic resistance was first documented in the 1940s, just years after sulfonamides and penicillin were introduced as the first effective cures for gonorrhea. Continue reading →. ...
The Neisseria species are believed to be non-clonal bacteria with a high degree of genetic transfer within and between different species [2, 3, 14-18]. Previous reports of transformation in N. meningitidis have suggested that different regions of the genome may have different recombination rates [19, 20]. This work identified the region upstream of folP as particularly active in recombination events. The most obvious example is the insertion of a complete Correia element, upstream of folP in N. lactamica. Correia elements are small putative transposable elements, around 152 base pairs long with inverted repeats at the ends [12]. Hundreds of Correia copies are scattered around the genomes of pathogenic Neisseriae [13, 21, 22] and they have also been reported in N. lactamica [23]. We detected another copy of a Correia repeat in the N. subflava sequence, suggesting that these elements are ubiquitous in the Neisseria genus and possibly was introduced before the divergence into different ...
In the context of our interest in host-pathogen interactions, we are pursuing currently the following projects:. Neisseria. We have developed a novel mouse model to study the mechanisms of commensalism, from the standpoint of both the host and bacterium. The model involves noninvasive inoculation of the well-studied lab mouse with a new commensal Neisseria species isolated from the normal flora of healthy wild mice. The model allows studies of colonization, and the elusive process of persistence, in a variety of mucosal niches, from the relatively well-studied intestinal tract to the less well-studied respiratory tract and oral cavity. Experimentation is guided by a vast store of knowledge on the mouse and close relatives of the bacterium. Using this unique model, we will identify immune processes and mouse genes critical for susceptibility to N. tucsonensis colonization and bacterial genes critical for colonization and persistence.. Valley Fever. Coccidioidomycosis is a serious respiratory ...
Author Summary The closely related bacterial species N. meningitidis, N. gonorrhoeae and N. lactamica exclusively colonise mucosal surfaces in humans. While N. gonorrhoeae leads to gonorrhea, the other two species persist mainly in their host in the absence of disease. N. meningitidis does occasionally cause severe, life threatening illness, however. Little is known about the factors and elements that dictate the unique human interactions exhibited by each species. Moreover, the evolutionary relationships between these species are poorly characterized. Here, we describe two successive alterations in a single gene that can be linked first to all species within the genus Neisseria and then the species N. meningitidis. We also show these signature alterations have phenotypic consequences by affecting core respiratory metabolic processes. These findings have significant implications for the evolution of related bacterial species within a single host and provide a novel perspective on the episodic and
The genus Neisseria contains many species. Most of them are part of the normal flora of humans and animals; only two are human pathogens: Neisseria gonorrhoeae, which causes a sexually transmitted disease of the same name, and Neisseria meningitidis, which causes meningitis. These pathogens often behave like their related commensal cousins in that they establish asymptomatic infection at high frequency. This commensal-like trait was likely inherited by the pathogens as they evolved from commensal species. Supporting this idea is the observation that many N. gonorrhoeae and N. meningiditis genes that mediate pathogen interactions with their hosts are also in the commensals. A major goal of our lab is to determine how commensal and pathogenic Neisseria differentially regulate these host interaction genes, and how these regulatory events might affect their lifecycle in the host.. Another goal of our lab is to use our new mouse model for Neisseria colonization, persistence, and asymptomatic ...
Manufacture and distribution of animal blood products, plasma, serum, microbiological diagnostic kits and quality control products, Buckinghamshire, UK
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
The insulin signaling pathways play key roles in energy metabolism, growth, and cellular differentiation. The key ligands for these pathways include the hormone insulin and insulin-like growth factors I and II (IGF1 and IGF2). These ligands bind with different affinities to insulin receptor and IGF1 receptor homo- and heteroduplexes. Receptor activation leads to downstream signaling through the MAPK and PI3K signaling pathways, ultimately activating target gene expression. Signaling through the insulin receptor either promotes mitogenesis or glucose and fatty acid storage. This pathway also inhibits lipid and carbohydrate degradation. Signaling through IGF1R promotes cell growth and inhibits apoptosis. Dysregulation of these pathways commonly occurs during carcinogenesis, possibly due to the prominent role of insulin signaling in mitogenesis. Insulin resistance is a common symptom of diabetes and obesity, resulting from dysregulated energy homeostasis ...
The insulin signaling pathways play key roles in energy metabolism, growth, and cellular differentiation. The key ligands for these pathways include the hormone insulin and insulin-like growth factors I and II (IGF1 and IGF2). These ligands bind with different affinities to insulin receptor and IGF1 receptor homo- and heteroduplexes. Receptor activation leads to downstream signaling through the MAPK and PI3K signaling pathways, ultimately activating target gene expression. Signaling through the insulin receptor either promotes mitogenesis or glucose and fatty acid storage. This pathway also inhibits lipid and carbohydrate degradation. Signaling through IGF1R promotes cell growth and inhibits apoptosis. Dysregulation of these pathways commonly occurs during carcinogenesis, possibly due to the prominent role of insulin signaling in mitogenesis. Insulin resistance is a common symptom of diabetes and obesity, resulting from dysregulated energy homeostasis ...
Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, BIOLOGY, NEISSERIA-MENINGITIDIS, POPULATION-STRUCTURE, GENETIC EXCHANGE, GENUS NEISSERIA, STREPTOCOCCUS, RECOMBINATION, PROKARYOTES, DEFINITION, PHYLOGENY, SEQUENCES. ...
Contains data for a collection of isolates that represent the total known diversity of Neisseria species. For every allelic profile in the profiles database there is at least one corresponding isolate deposited here. Any isolate may be submitted to this database and consequently it should be noted that it does not represent a population sample ...
Contains data for a collection of isolates that represent the total known diversity of Neisseria species. For every allelic profile in the profiles database there is at least one corresponding isolate deposited here. Any isolate may be submitted to this database and consequently it should be noted that it does not represent a population sample ...
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The availability of new polysaccharide-protein conjugate vaccines against Neisseria meningitidis serogroup C prompted European National Health authorities to carefully monitor isolate characteristics. In Italy, during 1999-2001, the average incidence was 0.4 cases per 100,000 inhabitants. Serogroup B was predominant and accounted for 75% of the isolates, followed by serogroup C with 24%. Serogroup C was isolated almost twice as frequently in cases of septicemia than in cases of meningitis, and the most common phenotypes were C: 2a:P1.5 and C:2b:P1.5. Among serogroup B meningococci, the trend of predominant phenotypes has changed from year to year, with a recent increase in the frequency of B:15:P1.4. Only a few meningococci had decreased susceptibility to penicillin, and, in the penA gene, all of these strains had exogenous DNA blocks deriving from the DNA of commensal Neisseria flavescens, Neisseria cinerea, and Neisseria perflava/sicca. Fluorescent amplified fragment-length polymorphism ...
Fumarase is one of the key enzymes in the TCA cycle and has been implicated in virulence and survival of some microorganisms under suboptimal environmental conditions. In this study, the fumC genes that encode fumarase C (FUMCs) from Neisseria meningitidis, N. gonorrhoeae and N. subflava were identified by homology-based analysis, cloned by polymerase chain reactions and fully sequenced. The inferred primary sequence of neisserial FUMCs showed a high degree of conservation with 97.8-98.7% amino acid identity. However, phylogenetic analysis revealed that these neisserial FUMCs are divergent from class II fumarases found in other microorganisms, rat and human. The putative fumC genes were subcloned into the expression vector, pGEX-6P-1 and efficiently expressed in Esherichia coli BL21. The purified recombinant fusion proteins obtained by affinity chromatography demonstrated high catalytic activities (120-180 U/mg), thus authenticating the identities and functionalities of the cloned genes. Whether ...
A DNA vaccine strategy for effective antibody induction to pathogen-derived antigens -- Antigen identification starting from the genome: A Reverse vaccinology Approach applied to MenB -- Analysis of the immune response to Neisseria meningitidis using a proteomics approach -- Analysis of parameters associated with prevention of cellular apoptosis by pathogenic Neisseriae and purified porins -- The use of the pan-Neisseria microarray and experimental design for transcriptomics studies of Neisseria -- Transcriptome analyses in the interaction of Neisseria meningitidis with mammalian host cells -- Visualising PAMP-PRR interactions using nanoscale imaging -- Hydrogen-deuterium exchange coupled to mass spectrometry to investigate ligand-receptor interactions -- Human dendritic cell culture and bacterial infection -- Techniques to measure pilus retraction forces -- A laminar-flow chamber assay for measuring bacterial adhesion under shear stress -- Methods for studying Neisseria meningitidis biofilms ...
A DNA vaccine strategy for effective antibody induction to pathogen-derived antigens -- Antigen identification starting from the genome: A Reverse vaccinology Approach applied to MenB -- Analysis of the immune response to Neisseria meningitidis using a proteomics approach -- Analysis of parameters associated with prevention of cellular apoptosis by pathogenic Neisseriae and purified porins -- The use of the pan-Neisseria microarray and experimental design for transcriptomics studies of Neisseria -- Transcriptome analyses in the interaction of Neisseria meningitidis with mammalian host cells -- Visualising PAMP-PRR interactions using nanoscale imaging -- Hydrogen-deuterium exchange coupled to mass spectrometry to investigate ligand-receptor interactions -- Human dendritic cell culture and bacterial infection -- Techniques to measure pilus retraction forces -- A laminar-flow chamber assay for measuring bacterial adhesion under shear stress -- Methods for studying Neisseria meningitidis biofilms ...
Neisseria spp. - Includes:Neisseria gonorrhoeaeNeisseria meningitidis - Neisseria gonorrhoeae - Neisseria meningitidis - Gram-negative diplococciContain lipooligosaccharides (LOS) with strong endotoxin activity - Contain lipooligosaccharides (LOS) with strong endotoxin activity - Facultatively intracellularOften visualized within epithelial cells - Often visualized within epithelial cells - Grows on Thayer-Martin agarSelective chocolate (heated-blood) agar-based medium containing the antibiotics vancomycin, colistin, nystatin and trimethoprimPrevents growth of microbes other than Neisseria - Selective chocolate (heated-blood) agar-based medium containing the antibiotics vancomycin, colistin, nystatin and trimethoprim - Prevents growth of microbes other than Neisseria - Produce IgA proteaseCleave IgA at hinge region, impairing its function at mucosal surfacesImproves mucosal adherence - Cleave IgA at hinge region, impairing its function at mucosal surfaces - Improves mucosal adherence - Increased risk
The Neisseria gonorrhoeae population structure is not clonal [1-5], its panmictic structure being the result of horizontal genetic exchange [6]. The pathogenic Neisseria spp. are naturally transformable [7] and chromosomal changes are largely mediated by homologous recombination. Natural competence for transformation and homologous recombination allow the generation of mosaic genes, such as the divergent opa genes [8, 9], antigenic variation through recombination with silent cassettes, such as in the pilE/pilS system [10, 11], and the horizontal exchange of whole genes or groups of genes in Minimal Mobile Elements (MMEs) [12]. A Minimal Mobile Element (MME) is defined as a region between two conserved genes within which different genes are found in different strains. These elements are described as minimal reflecting the fact that they do not have features suggesting mobilization by associated transposases, nor do they currently appear to have features by which remotely encoded systems would ...
Neisseria mucosa ATCC ® 49233™ Designation: AmMS 138 TypeStrain=False Application: Quality control of MicroScan ® panels
Looking for online definition of Neisseria ovis in the Medical Dictionary? Neisseria ovis explanation free. What is Neisseria ovis? Meaning of Neisseria ovis medical term. What does Neisseria ovis mean?
Looking for online definition of Neisseria in the Medical Dictionary? Neisseria explanation free. What is Neisseria? Meaning of Neisseria medical term. What does Neisseria mean?
After publication of the original article [1] it was identified that an incorrect version of the manuscript has been published. This was caused by a technical error which led to a discrepancy between the editorially-accepted version of the manuscript, and the published version.
The Neisseriaceae are a family[2] of Proteobacteria, within the Neisseriales order. While many organisms in the family are mammalian commensals or part of the normal flora, the genus Neisseria includes two important human pathogens, specifically those responsible for gonorrhea (caused by N. gonorrhoeae) and many cases of meningitis ("meningococcal meningitis", caused by N. meningitidis). As a group, the Neisseriaceae are strictly aerobic and Gram-negative, occur mainly in pairs (diplococci), and typically do not have flagella. ...
Tezera, L., Molierinho, S., Virji, M., Jackson, S. K. and Davenport, V. (2008) Differential induction on innate immunity to Neisseria lactamica and N.meningitidis in nasopharyngeal epithelial cells. In: 16th International Pathogenic Neisseria Conference, Rotterdam, 7-12 September 2008. Available from: http://eprints.uwe.ac.uk/7487 ...
Tezera, L., Molierinho, S., Virji, M., Jackson, S. K. and Davenport, V. (2008) Differential induction on innate immunity to Neisseria lactamica and N.meningitidis in nasopharyngeal epithelial cells. In: 16th International Pathogenic Neisseria Conference, Rotterdam, 7-12 September 2008. Available from: http://eprints.uwe.ac.uk/7487 ...
Bacillus amyloliquefaciens strain FZB42 is a free-living bacterium that competitively colonizes plant roots and stimulates plant growth by many different modes of action. The molecular basis of singular beneficial effects that this Plant Growth-Promoting Rhizobacteria (PGPR) exert on their hosts have been studied. To decipher the molecular cross-talk of B. amyloliquefaciens and its host plants as a whole system, an extensive proteomic approach was performed. Reference maps of the extracellular and cytosolic protein fractions were established. The highest number of secreted proteins was observed during stationary growth phase. Identified extracellular proteins belong to different functional classes, with the most prominent classes involved in carbohydrate degradation and transportation of molecules across the cell wall. Cytosolic extracts obtained from cultures grown in 1C and minimal media subjected to the 2 Dimensional Electrophoresis (2 DE), revealed 461 and 245 different protein entries, ...
The genome of the thermophilic fungus Scytalidium thermophilum (strain CBS 625.91) harbours a wide range of genes involved in carbohydrate degradation, including three genes, abf62A, abf62B and abf62C, predicted to encode glycoside hydrolase family 62 (GH62) enzymes. Transcriptome analysis showed that only abf62A and abf62C are actively expressed during growth on diverse substrates including straws from barley, alfalfa, triticale and canola. The abf62A and abf62C genes were expressed in Escherichia coli and the resulting recombinant proteins were characterized. Calcium-free crystal structures of Abf62C in apo and xylotriose bound forms were determined to 1.23 and 1.48 Å resolution respectively. Site-directed mutagenesis confirmed Asp55, Asp171 and Glu230 as catalytic triad residues, and revealed the critical role of non-catalytic residues Asp194, Trp229 and Tyr338 in positioning the scissile α-L-arabinofuranoside bond at the catalytic site. Further, the +2R substrate-binding site residues ...
The wood of the gender Eucalyptus occupies a prominence place among other cellulose sources due to its chemical composition, its low cost, abundance and availability. Among the chemical pulping processes, kraft process is the most extensively one used for the production of cellulosic pulps starting from eucalyptus wood. The anthraquinone (AQ) usage in the pulping has as main purposes to increase the delignification rate as well as to protect the pulp from the carbohydrate degradation. The present work has aimed to use the anthraquinone as an addictive in the cooking seeking to reduce the load of applied sulphidity without harming the quality of the pulp. The kraft and kraft/AQ cooking were accomplished in rotative laboratorial digester being varied the active alkali initially (10, 13, 16 and 19%) and, later, the sulphidity (5, 10, 15, 20 and 25%), maintaining the other conditions constant aiming to obtain pulp with kappa number close to nine. Starting from the variation of the active alkali and ...
General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria ...
General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and ...
|strong|Rabbit anti |em|Neisseria meningitidis|/em| antibody|/strong|reacts with |i|Neisseria meningitidis |/i| serogroups A, B and C recognizing multiple antigens. Other serogroups have not been test…
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Bacterial infection of human vasculature can lead to unregulated systemic activation of coagulation and innate immunity and rapidly becomes life threatening. Neisseria meningitidis is a vascular pathogen that causes fatal septic shock and meningitis. Post-mortem histological analysis of tissues from individuals infected with N. meningitidis show large bacterial aggregates in close association with the vascular wall of small vessels. The ability of this bacterium to colonize blood vessel endothelium is likely to impact its capacity to both multiply in the blood stream and reach the brain. This process is referred to as vascular colonization. Recent work from our group exploring the early steps in N. meningitidis vascular colonization will be reported, from attachment to proliferation and dissemination, focusing on the bacterial-host interaction.. Selected publications. ...
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Neisseria meningitidis, IgG, Vaccine Response, MAID (Quest). Get know how much does lab test cost. Direct access testing with or without insurance.
Domain combinations containing the TrpR-like superfamily in Neisseria meningitidis Z2491. Domain architectures illustrate each occurrence of the TrpR-like superfamily.
Neisseria gonorrheae bacteria are the causative agent of the second most common sexually transmitted infection in the world. The bacteria move on a surface by means of twitching motility. Their movement is mediated by multiple long and flexible filaments, called type IV pili, that extend from the cell body, attach to the surface, and retract, thus generating a pulling force. Moving cells also use pili to aggregate and form microcolonies. However, the mechanism by which the pili surrounding the cell body work together to propel bacteria remains unclear. Understanding this process will help describe the motility of N. gonorrheae bacteria, and thus the dissemination of the disease which they cause. In this article we track individual twitching cells and observe that their trajectories consist of alternating moving and pausing intervals, while the cell body is preferably oriented with its wide side toward the direction of motion. Based on these data, we propose a model for the collective pili ...
What do UK sexual health clinicians think about saliva as a transmissible vector for Neisseria g onorrhoea e in men who have sex with men? ...
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It is also called knock knees. It is a condition in which the knee angle is in and they touch each other when the legs are straightened ...
Out of the 13 identified serogroups of Neisseria meningitidis (Nm) the six serogroups (A, B, C, W, Y and X) are responsible for majority of infections.
2F46: Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 A resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.
Penyakit ini disebut juga kencing nanah. Penyebab penyakit ini adalah kuman Neisseria Gonorhea. Masa inkubasi berfariasi antara 2-10 hari. Peularan melalui hubungan seksual. Gejala keluarnya cairan kental atau nanah dari saluran kelamin pria dan wanita ...
Branhamella catarrhalis. Coloured Scanning Elect- ron Micrograph (SEM) of Branhamella catarrhalis bacteria, cause of ear and nose infections. These Gram- negative, brown-coloured spherical bacteria are usually found in pairs and hence referred to as diplococci. B. catarrhalis is associated with low-grade infections of the lower respiratory tract and occasionally with acute infections of the middle ear (otitis media) in immune deficient patients. Treatment is with antibiotics. Magnification: x6, 250 at 6x6cm size. - Stock Image B220/0866
Branhamella catarrhalis. Coloured Scanning Elect- ron Micrograph (SEM) of Branhamella catarrhalis bacteria, cause of ear and nose infections. These Gram- negative, green-coloured spherical bacteria are usually found in pairs and hence referred to as diplococci. Here they are seen alongside three red blood cells. B. catarrhalis is associated with low-grade infections of the lower respiratory tract and occasionally with acute infections of the middle ear (otitis media) in immune deficient patients. Treatment is with antibiotics. Magnification: x5,000 at 6x6cm size. - Stock Image B220/0863
The neisserial porins are the major protein components of the outer membrane of the pathogenic Neisseria (N. meningitidis and N. gonorrhoeae). They have been shown to be able to enhance the immune response to poorly immunogenic substances (e.g., polysaccharides, peptides, glycolipids, etc.). To explore the basis of their potent adjuvant activity, the effect of the neisserial porins on T-B cell interactions and T cell costimulation was examined. Neisserial porins increased the surface expression of the costimulatory ligand B7-2 (CD86) but did not affect the expression of B7-1 (CD80). In addition, incubation with the neisserial porins increased the T lymphocyte costimulatory ability of B lymphocytes, which was inhibited by anti-B7-2 but not anti-B7-1 monoclonal antibodies. Upregulation of B7-2 on the surface of B lymphocytes may be the mechanism behind the immunopotentiating activity of neisserial porins. ...
Mapping of monoclonal antibodies specific to P64k: A common antigen of several isolates of Neisseria meningitidis. Nazábal, C; Carmenate, T; Cruz, S; González, S; Silva, R; Musacchio, A; Delgado, M; Chinea, G // Canadian Journal of Microbiology;Feb2001, Vol. 47 Issue 2, p158 P64k is a minor outer membrane protein from Neisseria meningitidis. This protein has been produced at high levels in Escherichia coli. We generated a group of monoclonal antibodies (mAbs) against recombinant P64k, which recognise four non-overlapping epitopes, as shown using competition assays... ...
Neisseria gonorrhoeae MntC protein: a periplasmic-binding protein that be a component of an ABC transporter that imports manganese ion to combat oxidative stress; isolated from Neisseria gonorrhoeae; GenBank AE004969
Major outer membrane proteins (MOMP) from a mixture of detergent-treated Neisseria gonorrhoeae strains: SB587, SB2262, SB2265 & SB2275 ...
Gonorrhea is a sexually transmitted disease with a high morbidity burden. Incidence of this disease is rising due to the increasing number of antibiotic-resistant strains. Neisseria gonorrhoeae has shown an extraordinary ability to develop resistance to all antimicrobials introduced for its treatment. In fact, it was recently classified as a “Priority 2” microorganism in the WHO Global Priority List of Antibiotic-Resistant Bacteria to Guide Research, Discovery and Development of New Antibiotics. Seeing as there is no gonococcal vaccine, control of the disease relies entirely on prevention, diagnosis and, especially, antibiotic treatment. Different health organizations worldwide have established treatment guidelines against gonorrhea, mostly consisting in dual therapy with a single oral or intramuscular dose. However, gonococci continue to develop resistances to all antibiotics introduced for treatment. In fact, the first strain of super-resistant N. gonorrhoeae was recently detected in the
FITC偶联Neisseria gonorrhoeae抗体(ab20815)经ELISA, ICC/IF实验严格验证,实验条件参看说明书。Abcam对所有产品均提供质保服务和专属技术支持,中国75%以上现货。
Background: In 2013 the Centers for Disease Control and Prevention declared the emergence of multi-drug-resistant Neisseria gonorrhoeae (NG) infections to be one of the top three urgent threats to public health. In response we developed a rapid molecular assay to detect alterations in the gyrase A (gyrA) genotype of NG species conferring fluoroquinolone-resistance. In November 2015, UCLA Health began routine gyrA genotype testing NG positive specimens from the Cobas CT/NG assay (Roche Molecular Systems, Pleasant, CA). Methods: We reviewed patient records for all laboratory confirmed NG cases between January 1st 2015 and May 5th 2016 to determine HIV-infection status, time-to-treatment and gyrA genotype results by anatomic site. At least one NG infection detected from a patient on a single date was considered a case. Infections in different anatomic locations were considered unique infections. Results: Among 199 patients (84% men; 35% HIV-infected), there were 221 cases and 233 unique NG ...
This report published in Communicable Diseases Intelligence Volume 26, No 4, December 2002 contains information on a long-term program of surveillance of antimicrobial resistance in Neisseria gonorrhoeae isolated in the World Health Organizations Western Pacific Region which continued in 2001.
The immunological basis for resistance of certain strains of Neisseria gonorrhoeae to the bactericidal action of normal human serum was studied by investigating the potential role of factors which are known to interfere with each of the sequential steps that result in immune lysis of Gram-negative b …
Newcombe, J, Eales-Reynolds, L, Wootton, L, Gorringe, AR, Funnell, SGP, Taylor, SC and McFadden, JJ (2004) Infection with an avirulent phoP mutant of Neisseria meningitidis confers broad cross-reactive immunity ...
Domain combinations containing the 2Fe-2S ferredoxin-like superfamily in Neisseria meningitidis 053442. Domain architectures illustrate each occurrence of the 2Fe-2S ferredoxin-like superfamily.
[Monoarthritis in Neisseria meningitidis: What instructions for contact people?] Presse Med. 2017 Dec 21;: Authors: Pouliquen L, Daoudal A, Rabier V, Marleix S, Lucas G, Fraisse B, Violas P PMID: 29275971 [PubMed - as supplied by publisher]...
An apparatus for use in detecting Neisseria gonorrhoeae in females including a container and operative elements sealed therein. The test makes use of a dry pledget impregnated with reactant chemicals
Zaburdaev, V. ; Biais, N. ; Schmiedeberg, M. ; Eriksson, J. ; Jonsson, A. - B. ; Sheetz, M. P. ; Weitz, D. A. Uncovering the Mechanism of Trapping and Cell Orientation during Neisseria gonorrhoeae Twitching Motility. 2014, 107, 1523 - 1531.
This is the current revision of Neisseria gonorrhoeae as edited by Aschlafly (Talk , contribs) at 18:16, 14 July 2007. This URL is a permanent link to this version of this page ...
Neisseria meningitidis Orf1 antibody LS-C46154 is an unconjugated rabbit polyclonal antibody to neisseria meningitidis Neisseria meningitidis Orf1. Validated for WB.
Hardy Diagnostics CRITERION™ Hemoglobin Powder is used as a supplement for GC Agar Base in the preparation of Chocolate Agar. Chocolate Agar is used to cultivate fastidious organisms such as Neisseria spp. and Haemophilus spp. CRITERION™ Dehydrated Culture Media by Hardy Diagnostics is formulated to meet or exceed the highest standards. Compare these features…. ...
ID NEMEN2_1_PE1008 STANDARD; PRT; 146 AA. AC NEMEN2_1_PE1008; A1IRJ0; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE SubName: Full=Putative cell-surface protein; (NEMEN2_1.PE1008). GN OrderedLocusNames=NMA1173; OS NEISSERIA MENINGITIDIS Z2491. OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; OC Neisseria. OX NCBI_TaxID=122587; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEMEN2_1.PE1008. CC Neisseria meningitidis Z2491, complete genome. CC sequence. CC -!- ANNOTATIONS ORIGIN:A1IRJ0_NEIMA CC -!- GENE_FAMILY: HOG000218903 [ FAMILY / ALN / TREE ] DR UniProtKB/Swiss-Prot; A1IRJ0; -. DR EMBL; AL157959; CAM08377.1; -; Genomic_DNA. DR PIR; G81884; G81884. DR RefSeq; YP_002342571.1; NC_003116.1. DR EnsemblBacteria; EBNEIT00000000121; EBNEIP00000000121; EBNEIG00000000121. DR GeneID; 907142; -. DR GenomeReviews; AL157959_GR; NMA1173. DR KEGG; nma:NMA1173; ...
La presente invención se refiere a composiciones que incluyen un polipéptido de ORF2086 no lipidado no piruvilado aislado y a procedimientos de las mismas. En una realización de ejemplo, las composiciones descritas en el presente documento son inmunogénicas. La presente invención se refiere además a composiciones que producen una respuesta inmunológica bactericida en un mamífero contra un polipéptido ORF2086 de la subfamilia B de N. meningitidis del serogrupo B y a procedimientos relacionados con las mismas.
Methods DNA was extracted from 13 N. gonorrhoeae NAAT-positive urine specimens, enriched for microbial DNA and sequenced using the Ion Torrent PGM workflow. Sequences that aligned to the human genome were filtered out and the remaining sequences were de novo assembled. The resulting contigs were searched for regions of interest using Ridom SeqSphere. MLST and NG-MAST alleles were assigned according to the schemes at PubMLST.org and NG-MAST.net, respectively. ...
Guillaume Duménil : Neisseria meningitidis disseminates itself by sending out "scouts". Although, in the majority of cases, the localized presence of Neisseria meningitidis in the throat has no consequence, it can sometimes lead to meningitis or septicaemia. The seriousness of these two infections is driving researchers from around the world to improve their understanding of the mode of operation of this bacterium, which, once it leaves its favourite location (the throat) becomes extremely dangerous. The Avenir team directed by Guillaume Duménil within Inserm Mixed Research Unit 970, "Paris centre de recherche cardiovasculaire" at the Université Paris Descartes, has recently discovered how this bacterium disseminates, leaving the throat to pass into the bloodstream. Press release Inserm. Production : Ya k + prod. Durée : 2 min. 31 sec. ...
NG0402 is orthologously related to AE002435, Neisseria meningitidis, strain MC58, a putative ADP-heptose synthase protein: residues 1-320 are 96% similar to residues 1-320 of NG0402. NG0402 is orthologously related to AL162754, Neisseria meningitidis, strain Z2491, a putative DP-heptose synthetase protein: residues 1-320 are 95% similar to residues 1-320 of NG0402 ...
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Draw blood in a plain, red-top tube(s). Spin down and send 1 mL serum, refrigerated.   NOTE: Serum gel tube is acceptable, but must pour off into a plastic vial.  
2015 (English)In: Molecular Immunology, ISSN 0161-5890, E-ISSN 1872-9142, Vol. 67, no 1, Special Issue, p. 142-142, article id 067Article in journal, Meeting abstract (Refereed) Published ...
Sigma-Aldrich offers abstracts and full-text articles by [Johan Chanal, François Lassau, Philippe Morand, Michel Janier, Nicolas Dupin].
N. gonorrhoeae and N. meningitidis are exemplary for their ability to adapt to their sole host, the human. Both species possess the ability to colonize human mucosal tissues. N.gonorrhoeae primarily infects the uro- or anorectal mucosa following intimate sexual contact, while N. meningitidis colonizes the nasopharynx after the inhalation of infected respiratory ...
Medical bacteriology: . Pyogenic Cocci: Staphylococci. Streptococci Neisseriae species. Staphylococci : . Morphology: It is a Gram positive Cocci, one micrometer in diameter, arranged in clusters, non spore formers, and non-motile. Slideshow 2017803 by mahdis
NEISSERIA. Genus: Neisseria. This genus contains several more or less fastidious species of which following two are important pathogens.. ...
Tripel ( Gonorrhoea) - je chòroscą ù lëdzy. Jegò lékarzenié je mòżlëwi. Do chòroscë doprowôdzy bakteria Neisseria gonorrhoeae. Ta chòrosc biwô m.jin. w Africe, ale mòże bëc na Kaszëbach.. ...
Na Grécia, a Neisseria meningitidis aparece como casos esporádicos com alguns surtos sazonais locais. A notificação da infecção meningocócica, às autoridades de saúde e Ministério da Saúde, é obrigatória. Em 1994, o Centro Nacional de Referência para a Meningite (CNRM) foi reactivado para o desenvolvimento de uma rede entre hospitais e autoridades de saúde, que está a contribuir para o melhoramento do sistema de notificação.
penderita penyakit kencing nanah atau gonnore akan merasakan sakit pada bagian vitalnya dikarenakan neisseria gonorrhoeae yang menginfeksi pada lapisan dalam uretra, tenggorokan, rectum, bagian putih mata (konjungtiva), dan leher Rahim. Penyakit kencing nanah ini bisa menyebar melalui aliran darah ke bagian tubuh lainnya, terutama pada kulit dan persendian.
penderita penyakit kencing nanah atau gonnore akan merasakan sakit pada bagian vitalnya dikarenakan neisseria gonorrhoeae yang menginfeksi pada lapisan dalam uretra, tenggorokan, rectum, bagian putih mata (konjungtiva), dan leher Rahim. Penyakit kencing nanah ini bisa menyebar melalui aliran darah ke bagian tubuh lainnya, terutama pada kulit dan persendian.
Sedang mencari obat Kencing Nanah Atau Gonore ? Gonore adalah penyakit menular seksual yang disebabkan oleh Neisseria gonorrhoeae yang menginfeksi lapisan dalam uretra, leher rahim, rektum dan tenggorokan atau bagian putih mata (konjungtiva).Gonore bisa menyebar melalui aliran darah ke bagian tubuh lainnya, terutama kulit dan persendian.Pada wanita, gonore bisa naik ke saluran kelamin dan ...
Gonorrhoea is one of the most common forms of sexually transmitted diseases (STDs). Its caused by a bacterial pathogen known as gonococcus or neisseria
Gonorrhea is a sexually transmitted disease that can be treated, caused by a bacterium called Neisseria Gonorrhea. This bacterium can infect the genital tract, mouth, and rectum.
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Bayesian length-weight: a=0.00661 (0.00312 - 0.01398), b=3.01 (2.83 - 3.19), in cm Total Length, based on LWR estimates for this (Sub)family-body shape (Ref. 93245 ...
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Kingella kingae is a member of the Neisseriaceae and is being recognized increasingly as an important cause of serious disease in children. Recent work has demonstrated that K. kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells and are selected against during invasive disease. In the current study, we examined the genome of K. kingae strain 269-492 and identified homologs of the rpoN and the pilS and pilR genes that are essential for pilus expression in Pseudomonas aeruginosa but not in the pathogenic Neisseria species. The disruption of either rpoN or pilR in K. kingae resulted in a marked reduction in the level of transcript for the major pilus subunit (pilA1) and eliminated piliation. In contrast, the disruption of pilS resulted in only partial reduction in the level of pilA1 transcript and a partial decrease in piliation. Furthermore, the disruption of pilS in colony variants with high-density piliation resulted in variants with low-density ...
Objectives To improve the detection of Neisseria gonorrhoeae by designing a multiplex PCR assay using two N gonorrhoeae-specific genes as targets, thereby providing detection and confirmation of a positive result simultaneously.. Methods PCR primers were designed to detect two N gonorrhoeae genes, namely porA and pgi1. Primers for an internal control targeting the ompW gene of Vibrio cholerae were also designed and incorporated in the assay. The DNA of 45 clinical isolates including 33 N gonorrhoeae isolates, seven non-gonococcal Neisseria species, and five non-Neisseria species was tested using the multiplex PCR assay.. Results All 33 N gonorrhoeae isolates were successfully detected by the assay and none of the non-gonococcal isolates was detected. The assay showed a sensitivity and specificity of 100%, and a limit of detection of 1.25 ng of DNA.. Conclusion This multiplex PCR assay offers a sensitive and specific assay suitable for the detection of N gonorrhoeae, and offers real potential for ...
Pre o de Broncho-vaxom, laborat rio Takeda, droga: Lisado bacteriano + Diplococcus pneumoniae + Haemophilus influenzae + Klebsiella ozanae + Klebsiella pneumoniae + Neisseria catarrhalis + Staphylococcus aureus + Streptococcus. Encontre pre os atualizados de todos os medicamentos / rem dios / princ pios ativos comerciais e gen ricos.
View Stock Photo of Branhamella Catarrhalis Bacteria Bound To The Surface Of A Human Red Blood Cell Sem X9401. Find premium, high-resolution photos at Getty Images.
Branhamella catarrhalis activates human B lymphocytes following interactions with surface IgD and class I major histocompatibility complex antigens.
The primary purpose of this page is to provide illustrations of characteristics of N. meningitidis that may aid in differentiating between this, and other, Neisseria species that produce acid from glucose and maltose.. This page is not intended to be a definitive discussion of N. meningitidis infections but to provide information relating to the accurate identification of N. meningitidis and will include only traditional tests for the identification of this species, information on species that may be misidentified as N. meningitidis, and additional tests which should be performed to identify a gram-negative, oxidase-positive diplococcal strain accurately.. For information about meningococcal meningitis, visit the Meningococcal Disease page, Division of Bacterial Diseases.. ...