We demonstrate trapping and characterization of multiple gold nanospheres with a setup composed of dark field imaging and optical tweezers. The number of trapped nanospheres is quantified by the overall dark-field scattering intensity. The spectra of the scattering intensity show that there is no interparticle coupling among trapped nanospheres when the density of nanospheres in the trap is low enough (less than 10 particles), while the density of nanosphere increases the interparticle coupling of nanospheres becomes obvious. In addition, the trapping potential of a single gold nanosphere is obtained by trapping an ensemble of gold nanospheres.. ©2013 Optical Society of America. Full Article , PDF Article ...

Gold nanoparticles have attracted enormous interest as potential theranostic agents. However, little is known about the long-term elimination and systemic toxicity of gold nanoparticles in the literature. Hollow gold nanospheres (HAuNS) is a class of photothermal conducting agent that have shown promises in photoacoustic imaging, photothermal ablation therapy, and drug delivery. Its very necessary to make clear the biosafety of HAuNS for its further application. We investigated the cytotoxicity, complement activation, and platelet aggregation of polyethylene glycol (PEG)-coated HAuNS (PEG-HAuNS, average diameter of 63 nm) in vitro and their pharmacokinetics, biodistribution, organ elimination, hematology, clinical chemistry, acute toxicity, and chronic toxicity in mice. PEG-HAuNS did not induce detectable activation of the complement system and did not induce detectable platelet aggregation. The blood half-life of PEG-HAuNS in mice was 8.19 ± 1.4 hr. The single effective dose of PEG-HAuNS in

Page contains details about doxorubicin-loaded hollow gold nanospheres . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com

Highly porous nano carbon materials have been widely developed due to their advanced physical characteristics such as morphology, light weight, but more interestingly the possibility of designing the level of porosity as well as the specific surface area with many different approaches. This shows great potential in gas adsorption, separation, environmental treatment, energy storage and conversion, etc. Based on these properties, we investigated the synthesis of porous carbon nanosphere via two-steps process, using phenolic resol as a carbon source and block copolymer F127 as a soft template via hydrothermal process followed by graphitization. The porous nanospheres have high surface area of 1099 m2/g after KOH activation measured by nitrogen sorption isotherms. Furthermore, the surface chemistry was characterized by elemental analysis, infrared spectroscopy and x-ray photoelectron spectroscopy. The uniformity in the size of the nanospheres was verified by SEM and TEM analyses. The nanospheres show H2

Novel magnetic nanospheres with an average size of 118 nm utilizing N-methacryloyl-(L)-cysteine methyl ester (MAC) as a monomer were prepared by surfactant free emulsion polymerization of 2-hydroxyethyl methacrylate (HEMA) and MAC conducted in an aqueous dispersion medium. MAC was synthesized using methacryloyl chloride and L-cysteine methyl ester. L-Cysteine groups of the mag-poly(HEMA-MAC) nanospheres were chelated with Fe3+ ions. Specific surface area of the nonporous nanospheres was found to be 2452 m(2)/g. Mag-poly(HEMA-MAC)-Fe3+ nanospheres contained 0.81 mmol sulphur/g polymer were used in the adsorption of catalase in batch system. Using an optimized adsorption protocol, a very high loading of 820 mg catalase/g nanosphere was obtained. The adsorption phenomena appeared to follow a typical Langmuir isotherm. The immobilized catalase has more resistence to temperature inactivation than that of their free form. The optimum pH value of catalase was not affected by the immobilization ...

We present a comparative study of the toxicity of polyethylene glycol (PEG)-coated cobalt ferrite nanoparticles and nanospheres. Nanoparticles were prepared by hydrothermal method while nanospheres were prepared by solvothermal technique. The surface of nanomaterials was successfully modified with polyethylene glycol. To investigate the morphology of the prepared samples, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, thermogravimetric analysis (TGA), and electron microscopy techniques were employed. Structural analyses confirmed the formation of polycrystalline cobalt ferrite nanoparticles with diameters in the range 20-25 nm and nanospheres in the range 80-100 nm, respectively. Kunming SPF mice (female, 6-8 weeks old) were used to investigate the toxicity induced by cobalt ferrite nanoparticles and nanospheres in different organs of the mice. Biodistribution studies, biochemical indices, histopathological assessments, inflammatory factors, oxidation and

TY - JOUR. T1 - Regular patterns generated by self-organization of ammonium-modified polymer nanospheres. AU - Chen, Xin. AU - Chen, Zhimin. AU - Yang, Bai. AU - Zhang, Gang. AU - Shen, Jiacong. PY - 2004/1/1. Y1 - 2004/1/1. N2 - Macroscopic regular stripe-crack patterns have been observed in the course of drying the aqueous suspensions of ammonium-modified polymer nanospheres. These forms emerged because the evaporation of dispersed water and self-assembly of nanospheres originates shrinkage during drying the aqueous suspensions. The drying condition plays an important role as well as the nature of the ammonium-modified polymer nanospheres for the stripe-crack pattern formation. By means of the vertical deposition method, directional stripe-crack patterns have been achieved in the macroscopic scale. Surprisingly, we have still noted an interesting secondary stripe pattern occurred spontaneously on the stripes.. AB - Macroscopic regular stripe-crack patterns have been observed in the course of ...

TY - JOUR. T1 - High payload Gd(III) encapsulated in hollow silica nanospheres for high resolution magnetic resonance imaging. AU - Lin, Wan Ing. AU - Lin, Chien Yuan. AU - Lin, Yu Shen. AU - Wu, Si Han. AU - Huang, Yu Ru. AU - Hung, Yann. AU - Chang, Chen. AU - Mou, Chung Yuan. PY - 2013/2/7. Y1 - 2013/2/7. N2 - For clear MR imaging of blood vessels, a long blood circulation time of effective T1 contrast agents is necessary. Nanoparticulate MR contrast agents are much more effective owing to their enhanced relaxivity, a result of reduced tumbling rates, and large payloads of active magnetic species. PEGylated yolk-shell silica nanospheres containing high payloads of Gd(iii) with cross-linking ligands are synthesized and evaluated as a blood-pool magnetic resonance contrast agent. The hydrophilic PEG coating and the microporous silica shell allow water exchange while keeping the multi-nuclear Gd species from leaching out. These Gd(iii)-containing yolk-shell silica nanoparticles with PEGylated ...

TY - JOUR. T1 - Polarized fluorescent nanospheres. AU - Luchowski, Rafal. AU - Gryczynski, Zygmunt. AU - Földes-Papp, Zeno. AU - Chang, Aaron. AU - Borejdo, Julian. AU - Sarkar, Pabak. AU - Gryczynski, Ignacy. PY - 2010/3/1. Y1 - 2010/3/1. N2 - Fluorescent beads (nanoparticles, nanospheres) are commonly used in fluorescence spectroscopy and microscopy. Due to the random distribution of dye and high dye to nanoparticle ratio, the fluorescence polarization observed from the beads is low. Therefore beads are not used for polarization study. We demonstrate that photoselective bleaching creates beads with highly polarized fluorescence. First, the beads were immobilized in a PVA polymer. Second, the beads-doped PVA film was exposed to the illumination within the dye absorption band. A progressive decrease of absorption was observed. Next, photophysical properties of photobleached and not bleached films dissolved in water were compared.. AB - Fluorescent beads (nanoparticles, nanospheres) are commonly ...

A schematic process flow of the synthesis of Ag@SiO2@mSiO2 nanocarrier: (a) Monodispersed silver nanoparticles. (b) Depositing thin SiO2 layer (~10 nm in thickness) on the surface of Ag nanoparticles using TEOS as silicon source. (c) Coating mesoporous SiO2 layer (~35 nm in thickness) on the basis of Ag@SiO2 nanospheres by introducing CTAB as template and followed by CTAB removal. A schematic diagram of the fabrication procedure for modified microfiber sensor with mesoporous nanostructures: (d) As-prepared microfiber device by tapering technique. (e) Cleaning microfiber with ethanol and piranha solution. (f) Amino groups with positive charges bonding to abundant hydroxyl groups on the surface of fresh microfiber with APTES. (g) Implementing the functionalized fiber device under the circumstances of nanospheres with negative charges. Top-view SEM image of dispersed Ag@SiO2 nanospheres and Ag@SiO2@mSiO2 with higher amplification factor are shown in panels (h) and (i), respectively. (j) Side-view ...

Interaction of the CLPFFD peptide with gold nanospheres. A Raman, surface enhanced Raman scattering and theoretical study. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.

Article Preparation and characterisation of 5-fluorouracil containing PLGA nanospheres coated with chitosan, for drug delivery. The aim of this study was to design a new Drug Delivery System (DDS) based on poly (lactide-co-glycolide) (PLGA) biodegrad...

Fabrication of monodisperse pure silica and core-shell nanospheres (Fe2O3@SiO2 and Fe2O3/QD@SiO2) was done in straight forward one-pot method combining sol-gel chemistry and supercritical fluids. For the core-shell materials, preformed nanoparticles stabilized in hexane were dispersed in a sol containing a silicon alkoxide, water and acetone as the solvent. The precursor solution was introduced in an autoclave and pressurized with compressed CO2. Then, pressure and temperature were raised over the supercritical conditions of the CO2/acetone mixture allowing the silicon alkoxide to hydrolyze and condensate forming the silica shell. The composite gel nanospheres got dried as the solvent was extracted at supercritical conditions. They present a narrow particle size distribution (with less than 30% polidispersity). Each nanosphere consists of a functional core of several non-contacting γFe2O3 nanoparticles and/or quantum dots surrounded by a microporous silica shell. Their size can be tuned by controlling

Nanosphere lithography, an inexpensive and high throughput technique capable of producing nanostructure (below 100 nm feature size) arrays, relies on the formation of a monolayer of self-assembled nanospheres, followed by custom-etching to produce nanometre size features on large-area substrates. A theoretical model underpinning the self-ordering process by centrifugation is proposed to describe the interplay between the spin speed and solution concentration. The model describes the deposition of a dense and uniform monolayer by the implicit contribution of gravity, centrifugal force and surface tension, which can be accounted for using only the spin speed and the solid/liquid volume ratio. We demonstrate that the spin recipe for the monolayer formation can be represented as a pathway on a 2D phase plane. The model accounts for the ratio of polystyrene nanospheres (300 nm), water, methanol and surfactant in the solution, crucial for large area uniform and periodic monolayer deposition. The ...

Page contains details about poly(nitrophenyl methacrylate-co-isopropylacrylamide-co-methacryloxypropyltrimethoxysilane)-coated silica nanospheres . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com

Uniform-sized silica nanospheres with a well-ordered arrangement were successfully synthesized by a novel and simple method; hydrolysis and condensation reactions of tetraethyl orthosilicate were conducted in the presence of basic amino acids.

A one-step method to prepare core-shell nanoparticles and thus hollow nanospheres is reported. The process for the formation of core and shell took place during reaction. Once the core formed, it was covered with the shell substance produced in situ, and thus, the shell hindered the continued growth of the core. Based on this method, we readily obtained core-shell nanoparticles by choosing AgCl, CuS, or Fe(III) diethyldithiocarbamate (FeDEC)3 as model core substances and the cogel from gelatin and gum arabic as the shell substance. High-resolution transmission electron microscopy (HRTEM) directly revealed the core-shell structure. TEM results showed the average particle sizes were under 100 nm, depending on the core substance and the concentration of substances producing cores. After removal of the core materials, hollow nanospheres resulted, which were directly observed by TEM. The observation further verified the core-shell structure. UV spectrophotometry also gave signals of coated structure ...

Since energy economy and environmental safety are of major concern currently, here we report a simple, greener, template-free synthesis route to prepare tin oxide (SnO2) hollow and solid core nanospheres. The formation and growth mechanisms of such tin oxide nanospheres with solid and hollow cores having sizes of 50 nm-200 nm have been elucidated for the first time in this report. The electrochemistry of such hollow and solid spheres has been investigated against Li/Li+. Tin oxide (without an in situ conductive carbon coating) with a hollow core anode morphology exhibits an outstanding energy density of similar to 600 mA h g(-1) at a current density of 178 mA g(-1). Our electrochemical results and the discussion about hollow and solid core formation mechanisms, indicate the importance of our work and the electrochemical properties indicate that they could be used as anodes for lithium-ion batteries ...

We offer NIST traceable latex (polystyrene) and melamine standard microspheres and nanospheres in sizes from 50nm up to 100micron, standard microspheres, standard nanospheres, particle size standards

Due to the increased prevalence of resistant bacterial isolates which are no longer susceptible to antibiotic treatment, recent emphasis has been placed on finding alternative modes of treatment of wound infections. Bacteriophage have long been investigated for their antimicrobial properties, yet the utilization of phage therapy for the treatment of wound infections relies on a suitable delivery system. Poly(N-isopropylacrylamide) (PNIPAM) is a thermally responsive polymer which undergoes a temperature dependent phase transition at a critical solution temperature. Bacteriophage K has been successfully formulated with PNIPAM nanospheres copolymerized with allylamine (PNIPAM-co-ALA). By utilizing a temperature responsive polymer it has been possible to engineer the nanospheres to collapse at an elevated temperature associated with a bacterial skin infection. The nanogels were reacted with surface deposited maleic anhydride in order to anchor the nanogels to non-woven fabric. Bacteriophage ...

Fargo, N.D. - A patent-pending technology to produce nanospheres developed by a research team at North Dakota State University, Fargo, could enable advances across multiple industries, including electronics, manufacturing, and biomedical sectors. The environmentally-friendly process produces polymer-based nanospheres (tiny microscopic particles) that are uniform in size and shape, while being low-cost and easily reproducible. The process developed at NDSU allows scale-up of operation to high production levels, without requiring specialized manufacturing equipment. A 3a.m. Eureka! Moment Dr. Victoria Gelling, associate professor in the Department of Coatings and Polymeric Materials at NDSU, had a Eureka! moment when she woke early one morning - 3 a.m., to be precise, an hour when most of us are still sleeping. Gelling used early morning creativity to imagine a new way to oxidize monomers, which are relatively small and simple molecules, into polymers, which are larger, more complex molecules ...

We report measurements and theoretical analysis of resonant spin tunneling in randomly oriented nanospheres of a molecular magnet. Amorphous nanospheres of Mn₁₂ acetate have been fabricated and characterized by chemical, infrared, TEM, X-ray, and magnetic methods. Magnetic measurements have revealed sharp tunneling peaks in the field derivative of the magnetization that occur at the typical resonant field values for the Mn₁₂ acetate crystal in the field parallel to the easy axis.Theoretical analysis is provided that explains these observations. We argue that resonant spin tunneling in a molecular magnet can be established in a powder sample, without the need for a single crystal and without aligning the easy magnetization axes of the molecules. This is confirmed by re-analyzing the old data on a powdered sample of non-oriented micron-size crystals of Mn₁₂ acetate. In conclusion, our findings can greatly simplify the selection of candidates for quantum spin tunneling among newly ...

We report measurements and theoretical analysis of resonant spin tunneling in randomly oriented nanospheres of a molecular magnet. Amorphous nanospheres of Mn₁₂ acetate have been fabricated and characterized by chemical, infrared, TEM, X-ray, and magnetic methods. Magnetic measurements have revealed sharp tunneling peaks in the field derivative of the magnetization that occur at the typical resonant field values for the Mn₁₂ acetate crystal in the field parallel to the easy axis.Theoretical analysis is provided that explains these observations. We argue that resonant spin tunneling in a molecular magnet can be established in a powder sample, without the need for a single crystal and without aligning the easy magnetization axes of the molecules. This is confirmed by re-analyzing the old data on a powdered sample of non-oriented micron-size crystals of Mn₁₂ acetate. In conclusion, our findings can greatly simplify the selection of candidates for quantum spin tunneling among newly ...

TY - PAT. T1 - Nanosphere/Microsphere Delivery System for the Treatment of Spinal Cord Injury. AU - Stelzner, Dennis J.. AU - Osterhout, Donna J.. AU - Hasenwinkel, Julie M.. PY - 2011/9/1. Y1 - 2011/9/1. N2 - A formulation including injectable biodegradable nanospheres and/or microspheres as a delivery system for chondroitinase ABC (cABC) or a functional derivative of cABC to treat acute and chronic spinal chord injury in a mammal having the same is provided. The biodegradable nanosphere/microsphere formulation releases cABC or a functional derivative of cABC in a time-released manner at the site of the spinal cord injury. cABC infusion can promote axon regrowth and some behavioral recovery. The nanospheres and/or microspheres provided herein include cABC or a functional derivative of cABC loaded within and/or on a biodegradable polymer matrix. In some embodiments of the present invention, the surface of the biodegradable polymer matrix can be modified to target a specific scar site. In ...

This work addresses a new configuration that improves the sensitivity of a humidity sensor based on a long-period fiber grating coated with a SiO2-nanospheres film. An intermediate higher refractive index overlay, deposited through Electrostatic Self-Assembly, is placed between the fiber cladding and the humidity sensitive film in order to increase the total effective refractive index of the coating. With this intermediate design, a three-fold improvement in the sensitivity was obtained. Wavelength shifts up to 15 nm against 5 nm were achieved in a humidity range from 20% to 80%.

Amorphous carbon nanosphere used as the anode material for Li-intercalation in Lithium-ion energy storage. This structure was obtained through a thermal annealing process at a temperature of 3000 degree Kelvin, simulated using the LAMMPS molecular dynamics code on the LCRC Fusion resource ...

Eu(DBM),SUB,3,/SUB,Phen-embedded silica nanospheres were synthesized through a simple water-in-oil (W/O) microemulsion method. TEM observation indicates that the nanospheres are ≈40 nm in diameter and with a uniform core/shell structure. Compared to Eu(DBM),SUB,3,/SUB,Phen complex, the nano-hybrid-spheres shows similar emissions of Eu,SUP,3+,/SUP, ions under 355-nm excitation. By dynamic analysis at low temperature and laser selective excitation spectra, we found that there are two luminescent centers formed in the nanohybrids.. ...

Glioblastoma multiforme (GBM) remains the most aggressive and challenging brain tumour to treat. We report the first successful chemo-radiotherapy on patient derived treatment resistant GBM cells using a cisplatin-tethered gold nanosphere. After intracellular uptake, the nanosphere effects DNA damage which i

This study explores the potential of 177Lu-labeled carbon nanospheres as radio-nanoprobes for molecular imaging and therapy. The carboxyl functionalized surface of carbon nanospheres (CNS) was conjugated with [Gly-Gly-Gly-c(Asn-Gly-Arg)], G3-cNGR peptide through amide bond for targeting tumor vasculature and with [2-(4-Aminobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid], p-NH2-Bz-DOTA for chelation with 177Lu. The nanosphere-peptide conjugate, DOTA-CNS-cNGR, was characterized by dynamic light scattering and zeta potential measurements, IR and UV experiments and did not show any in vitro cytotoxicity ...

Increasing evidence indicates that carbon nanoparticles (CNPs), which mainly originate from incomplete combustion of fossil fuels, have an adverse impact on the respiratory system. Recent in vivo experiments have shown that the pulmonary toxicity of CNPs is attributed to their aggregation in pulmonary surfac

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Graphene paper as a new form of graphene-supported nanomaterials has received worldwide attention since its first report in 2007. Due to their high flexibility, lightweight and good electrical conductivity, graphene papers have demonstrated the promising potential for crucial applications in electrochemical sensors and energy technologies among others. In this chapter, we present some examples to overview recent advances in the research and development of two-dimensional (2D) graphene papers as new materials for electrochemical sensors. The chapter covers the design, fabrication, functionalization and application evaluations of graphene papers. We first summarize the mainstream methods for fabrication of graphene papers/membranes, with the focus on chemical vapour deposition techniques and solution-processing assembly approaches. A large portion of this chapter is then devoted to the highlights of specific functionalization of graphene papers with polymer and nanoscale functional building blocks for

The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization-Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups ([BOND]NH2) on the internal shell and carboxylic acid groups ([BOND]COOH) on the external shell. The selective functionalization has been realized by a combination of step-by-step post-grafting and cationic surfactant-assisted selective etching strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization-Henry cascade reaction in terms of both activity (,99 %) and selectivity (95 %).. ...

In this research, self-assembled copper sulfide nanospheres were synthesized by the solvothermal method and the effects of reaction parameters, including reaction time and reaction temperature on the morphology and phase evolution of copper sulfide nanostructures were investigated. For the identification of copper sulfide nanostructures, X-ray diffraction (XRD), infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FE-SEM), and elemental analysis (EDX) were used. The results showed that the temperature of 200 °C for 24 h is sufficient for the formation of the pure hexagonal Cu7.2S4 phase. The Cu7.2S4 nanostructures have a spherical morphology that formed from the self-assembly of the nanoparticles. Finally, the photocatalyst efficiency of Cu7.2S4 sphere was investigated.

High axial aspect crystalline nanomaterials have emerged as polymeric building blocks for the construction of supermaterials. In contrast to this form, amorphous nanospheres have remained largely untapped. This is especially peculiar in the context of material assembly, due to the wide range of opportunities they offer by virtue of their soft particle characteristics, high volume ratio at low solid content and their highly swollen and accessible structure. In the context of cellulose, these colloids represent a new field in the family of nanocelluloses. We report an organic solvent-free, heterogeneous and simple synthesis of spherical carboxylated nanoparticles bearing a distinctive, amorphous outer shell structure. The particle shape is evaluated by atomic force microscopy, cryo-transmission electron microscopy, dynamic light scattering and small-angle X-ray scattering. The soft shell structure of the particles and their responsiveness to ionic strength and pH are quantified by the combination ...

We specialize in Nanospheres, Microspheres, Microparticles, and Nanoparticles that are perfect for drug delivery services. Available at Phosphorex.com

Silver nanospheres 50 nm avg. part. size, 0.02 mg/mL (in 2mM aqueous sodium citrate), citrate functionalized; Linear Formula: Ag; find Sigma-Aldrich-796131 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.

The present invention relates to the use of certain microspheres, nanospheres, and other structures to provide a method of marking or masking identifying marks in individual biological hosts. Biological hosts for the present invention may include humans, other animals, or plants. Such methods may be used to sense, signal, track, mark, or identify individual biological hosts. Microspheres, nanospheres, and other structures of the present invention may be implanted, injected, ingested, or attached to individual biological hosts. Microspheres, nanospheres, and other structures of the present invention comprise poly[bis(trifluoroethoxy)phosphazene] and/or a derivative thereof which may be present throughout the particles or within an outer coating of the particles. The microspheres, nanospheres, and other structures may also comprise a core having a hydrogel which may further comprise one or more dyes or other chromophoric agents covalently bound permanently to the hydrogel core material. The microspheres,

Sigma-Aldrich offers Aldrich-807559, Silver nanospheres for your research needs. Find product specific information including CAS, MSDS, protocols and references.

Our melamine nanospheres and microspheres are highly spherical, monodisperse with highest possible density of surface amino groups. The technology we apply allow us to produce these melamine particles having the density of amino surface groups to one NH or NH2 groups at every nm2. For example each particle with 1μm diameter will have at least 3,000,000 surface amino groups.. Surface of amino melamine microparticles are terminated with amino groups, which could be used for various conjugation reactions. ...

Lan GJ,Zhang XM,Zhang XM,et al. Yolk-shell nanospheres with soluble aminopolystyrene as a reservoir for Pd NPs[J]. RSC Advances,2016,5(0):35730 ...

The delivery of unique nanospheres has aroused wide attention due to the potential applications in optical, electrical, magnetic, and biological devices.

Tin oxide (SnO2) has been considered as one of the most promising anodes for advanced rechargeable batteries due to its advantages such as high energy density, earth abundance and environmental friendly. However, its large volume change during the Li-Sn/Na-Sn alloying and de-alloying processes will result in a fast capacity degradation over a long term cycling. To solve this issue, in this work we design and synthesize a novel honeycomb-like composite composing of carbon encapsulated SnO2 nanospheres embedded in carbon film by using dual templates of SiO2 and NaCl. Using these composites as anodes both in lithium ion batteries and sodium-ion batteries, no discernable capacity degradation is observed over hundreds of long term cycles at both low current density (100 mA g(-1)) and high current density (500 mA g(-1)). Such a good cyclic stability and high delivered capacity have been attributed to the high conductivity of the supported carbon film and hollow encapsulated carbon shells, which not ...

The aim of this work is to investigate synthesis conditions of water insoluble β-cyclodextrin (β-CD) nanospheres that could be useful as an adsorbent to remove very low concentration of p-nitrophenol (p-NP) from water. The effect of several parameters on β-CD polymer synthesis such as β-CD/epichlorohydrin (EPI) mole ratio, reaction temperature and NaOH concentration was investigated. The FTIR-ATR analysis confirmed the formation of β-CD polymer structure with the addition of EPI by preserving the basic β-CD structural units. To determine the optimal synthesis conditions, performances of the synthesized β-CD nanospheres were determined by measuring the adsorption efficiencies of p-NP. On the basis of these results, the optimal synthesis conditions of β-CD nanospheres were 65°C, 40% NaOH (w/w) concentration and β-CD/EPI=1/55 mole ratio. Langmuir and Freundlich isotherm models were fitted on experimental data. It was found that Langmuir model described best for adsorption of p-NP onto ...

This case report shows an alternative approach for treating peri-implantitis, presenting clinical results after application of bioresorbable polymeric doxycycline 10% loading nanospheres as an adjunct to nonsurgical debridement.

The US Patent Office has issued a patent to Massachusetts-based Aphios Corporation for the oral delivery of insulin.. Patent No. 8,440,614, Polymer Microspheres/Nanospheres and Encapsulating Therapeutic Proteins Therein, covers the design of an insulin delivery system that would eliminate the need for injections.. Calling an oral delivery system one of the Holy Grails of biotechnology and drug development, Aphios says its patent gets around the greatest roadblock oral insulin developers have always faced: How to get insulin intact into the bloodstream before the digestive systems powerful enzymes can tear apart the hormones delicate protein molecules.. The companys oral insulin product now under development, APH-0907, encapsulates insulin in biodegradable, hydrophobic polymer nanospheres. In laymans terms, hydrophobic polymers are tough, water-repellant materials whose molecular bonds are numerous and strong. Nanospheres are microscopic drug-bearing orbs made from the polymers.. The ...

The molecular imprinting techniques have been extensively studied for molecular recognition and their potential applications to separation and catalysis. The traditional imprinting method uses the crosslinking polymerization in the presence of a substrate molecule followed by grinding the bulk system to microparticles with an irregular shape. In addition, the imprinting is restricted to a hydrophobic substrate because the polymerization reaction is usually done in the organic solvent using hydrophobic monomers. In this case, the irregular shape and microparticle size might be a concern for microelectromechanical system (MEMS) application as a biosensor. In this study, we investigated a well-defined nanosphere with a core-shell structure for molecular imprinting. The hydrophilic substrates including D-glucose (D-Glu) or L-phenylalanine (L-Phe) were imprinted on the surface (shell) of nanosphere and their binding behavior were investigated. Their enantiomer (L-Glu or D-Phe) binding behavior to the ...

Photoacoustic tomography (PAT) utilizes non-ionizing energy to obtain structural/functional information with high spatial resolution and sensitivity. Heterogeneous absorption of optical energy in biological tissues results in differentially expressed acoustic signals yielding spatial/temporal information. A critically underdeveloped area in PAT is the development of contrast agents. Gold-containing nanoparticles can be a good choice due to their high bio-compatibility, low toxicity, high feasibility of surface modification/conjugation. Here we present a broad evaluation of gold-containing nanoparticle for PAT contrast agents with different sizes and optical absorption properties. Gold nanospheres with diameters of 2-60nm generated PAT contrast enhancement at visible-light region. The enhancement increased with increasing size. Encapsulation of gold nanospheres using liposomes provides increased enhancement and shift in optical absorption to above 600nm. The highest contrast enhancement was obtained

The nanoscale responses of teeth to chewing loads are poorly understood. This has contributed to debate concerning the aetiology of enamel wear and resistance to fracture. Here we develop a new model for reactions of individual hydroxyapatite nanofibres to varying loads and directions of force. Hydroxyapatite nanofibres, or crystallites, composed of chains of bonded nanospheres, are the fundamental building blocks of enamel. This study indicates that these nanofibres respond to contact pressure in three distinct ways depending on force magnitude and direction: (i) plucking (nanosphere loss when the strength of the bonding protein glue is exceeded), (ii) plastic deformation (compression to gradually bend nanofibres and squeeze the protein layer), and (iii) fragmentation (nanofibres fracture when the strength of H-bonds that bind smaller nanoparticles into nanospheres is exceeded ...

Kawashima Y, Yamamoto H, Takeuchi H, Hino T, Niwa T (1998) Properties of a peptide containing DL-lactide/glycolide copolymer nanospheres ready by novel emulsion sol- slit diffusion methods. Children m

A promising sustainable strategy to valorize cellulose to high-value adsorbents for trace pharmaceuticals, like diclofenac sodium (DCF), in the water is demonstrated. Carbon nanospheres (CN) as the DCF adsorbent were derived from cellulose through a one-pot microwave-assisted hydrothermal carbonization method. CN exhibited efficient DCF removal (100% removal of 0.001 mg/mL DCF in 30 s and 59% removal of 0.01 mg/mL DCF in 1 h). The adsorption kinetics and isotherm data were well-fitted with the pseudo-second-order kinetic model and Langmuir model, respectively. The adsorption process was endothermic and spontaneous as confirmed by the thermodynamic parameters. Multiple characterization techniques including SEM/EDS, FTIR, FTIR-imaging and zeta potential were applied to qualitatively investigate the adsorption process. π-π stacking and hydrogen bonding were proposed as the dominant adsorption interactions. CN also demonstrated effective adsorption capacity towards three other commonly-detected ...

Radiation therapy occupies an important position in the treatment of malignant diseases in spite of the existence of radiation side effects on normal tissues. Thus, substances are being developed which are designed to reduce both the acute and long term radiation effects on healthy tissues. Currently a sulphur-containing compound amifostine (WR2721, ethyol) is used in clinical practice as a radioprotectant. However, it itself has considerable side effects including hypotension (found in 62% of patients), hypocalcaemia, diarrhoea, nausea, and vomiting. Carbon nanospheres, known as fullerenes, and their water soluble derivatives (e.g. C60(OH)24, dendrofullerene DF-1) exert anti-oxidative properties and reduce damage to the DNA in irradiated cells. Water soluble fullerenes are low-toxic substances and thus, are attractive in terms of their use as radioprotectants ...

The structure of a polymeric material has a great influence in many fundamental scientific areas as well as in more applied science, since it affects the diffusion, permeability, mechanical strength, elasticity, and colloidal properties of the materials. The results in this thesis demonstrate that it is possible to fabricate solid and hollow cellulose spheres with a cellulose shell and encapsulated gas, liquid or solid particles and with a sphere size ranging from a few hundreds of nanometres to several millimetres, all with a tailored design and purpose.. The sizes of the different spheres have been controlled by three different preparation methods: large cellulose macrospheres by a solution solidification procedure, hollow micrometre-sized cellulose spheres by a liquid flow-focusing technique in microchannels, and nanometre-sized cellulose spheres by a membrane emulsification technique. The spheres were then modified in different ways in order to functionalize them into more advanced ...

We live on a sphere. We play games with spheres. We eat spheres. We breathe spheres. From the immensity of astronomy to the minutia of microscopy, spheres are so prevalent, they can be found at every observable scale in the universe.

Nanoparticles with a mean diameter of 485 nm were readily prepared from a 2% PLGA solution in DCM at 32W sonication power (Tab. 1). The size distribution was mono-modal with a slight tailing (Fig. 3A). Nanoparticle sizes extended from 175 to 755 nm according to the 10 and 90% percentiles. Repeatability of the production process was consistently good, as reflected by only minor variability in the mean particle diameter. Lowering the emulsions residence time in the sonic field from 14 to 7s had only a minor impact on the nanoparticle size. A reduction of the sonication power from 32 to 25W, however, resulted in a significant increase of the mean particle size from 485 to 700nm, caused by a more pronounced tailing of the size distribution curve (Fig. 3A). A less prominent, though significant increase in the mean particle size from 485 to 600 nm was found when using a 5% instead of a 2% PLGA solution.. Finally, the more hydrophilic PLGA was exchanged for the more hydrophobic and lower molecular ...

Strains C4, C6 and C7 reduced tellurite at maximum reduction rates of 2.3, 1.5 and 2.1 mg Te (IV)/L/d, respectively and produced extracellular Te0 nanospheres as revealed from SEM-EDX analysis. Production of extracellular Te nanospheres has been described seldom. Further, concurrent reduction of both selenite and tellurite by bacteria was examined as these toxic oxyanions are often present together in natural environments, mine tailings or wastewater from copper refining. Interestingly, bioreduction of 100 mg/L selenite in s ... mehrhake flasks was not much affected by the presence of 10 mg/L tellurite but tellurite reduction rate increased 13 fold with selenite in the medium. The concurrent reduction of these oxyanions resulted in rarely described bioformation of extracellular nanoparticles composed of both Se and Te, reported first time for aerobically growing heterotrophic non-halophilic bacterial cultures. Duganella violacienigra, the closely related strain to C4 was also found to be ...

Oral drug administration remains the most convenient and preferred route of delivery. However, oral extended-release drug products have not yet reached their f...

We report a class of multi-functional core-shell nanoarchitectures, consisting of silica nanospheres as the core and Gd2O3:Dy(3+) nanocrystals as the ultra-thin shell, that enable unique multi-color living cell imaging and remarkable in vivo magnetic resonance imaging. These types of targeted cell imaging nanoarchitectures can be used as a variety of fluorescence nanoprobes

NanoSphere Health Sciences, Inc. (CSE: NSHS) (OTC: NSHSF), the biotechnology leader behind the patented NanoSphere Delivery System™, today announced the expansion of its CBD-dominant product-the Evolve Formulas Transdermal NanoSerum™CBD with Resveratrol-across Colorado due to co...

This week, .US has selected Nanosphere as the Site of the Week. A great example of American-based scientific innovation at its core, Nanosphere is a molecular diagnostic platform that helps hospitals around the cou ... ...

MIKROFLUIDIK UND NANOFLUIDIK; MIKROPARTIKEL + NANOPARTIKEL + MIKROSPHÄREN + NANOSPHÄREN (NANOTECHNOLOGIE); SELBSTORGANISATION (NANOSTRUKTURIERTE MATERIALIEN); MICROFLUIDICS AND NANOFLUIDICS; MICROPARTICLES + MICROSPHERES + NANOPARTICLES + NANOSPHERES (NANOTECHNOLOGY); SELF-ORGANIZATION (NANOSTRUCTURED MATERIALS ...

We present a theoretical model for analyzing the size dependence of the surface plasmon resonance of metallic nanospheres in a range of sizes down to a single nanometer. Within this model, we explicitly show how different microscopic mechanisms, namely quantization due to size (quantum size effect (QSE)) and dynamical surface screening, affect the energy of the surface plasmon. We demonstrate that the latter mechanism, which can move the surface plasma energy both toward the red or the blue, can be comparable to or even stronger than QSE. Thus, depending on material parameters, QSE may only be observed for ultra-small metal nanoparticles much closer to 1 nm in size than to 10 nm. Results presented herein are in quantitative agreement with recent published experimental results for Ag and Au.

22,000 g/mol PVOH did not form a hydrogel. After three freeze thaw cycles (24 hours @ -20°C, 24 hours at room temperature) the sample was still very much a liquid. This being said, we have concluded this molecular weight is not suitable for our drug delivery system. -nanospheres that were prepared on Wednesday may be too small for our system. We are looking to alter the procedure slightly so we can make spheres slight bigger (micro or even milli scale) ...

We replicate known seedless synthesis and seeded growths of Au and Ag nanoplates to create a plate with concavities that act as Surface Enhanced Raman Scattering (SERS) hotspots. Firstly, we recreated a seedless synthesis of gold nanoprisms, to which SiO2 nanospheres were attached. Next, different amounts of TEOS was added (to further increase volume of silica sphere.) When set to the right conditions, the gold tips that are not covered in silica will act as seeds for the extended growth . Once the product has the desired morphology the silica is washed off using HCl and its desired morphology should remain. Due to time restraints the SERS properties of the substrate were not tested. In theory the concavities are where the electric field enhancement will occur.

The invention describes improved methods for incorporating nucleic acids into polymeric microspheres and/or nanospheres through the use of a condensing agent.

Background: Low-intensity ultrasound (LIUS) was shown to be beneficial in mitigating inflammation and facilitating tissue repair in various pathologies. Determination of the molecular mechanisms underlying the anti-inflammatory effects of LIUS allows to optimize this technique as a therapy for the treatment of malignancies and aseptic inflammatory disorders. Methods: We conducted cutting-edge database mining approaches to determine the anti-inflammatory mechanisms exerted by LIUS. Results: Our data revealed following interesting findings: 1) LIUS anti-inflammatory effects are mediated by upregulating anti-inflammatory gene expression; 2) LIUS induces the upregulation of the markers and master regulators of immunosuppressor cells including MDSCs (myeloid-derived suppressor cells), MSCs (mesenchymal stem cells), B1-B cells and Treg (regulatory T cells); 3) LIUS not only can be used as a therapeutic approach to deliver drugs packed in various structures such as nanobeads, nanospheres, polymer microspheres,

Article Increasing contact area of microelectrodes in implantable microchannel array system for peripheral nerve regenerative using metal deposited nanospheres. Electromechanical guidance of neuron outgrowth is an essential route to promote nerve reg...

A simple, rapid and sensitive method for determination of trace levels of domoic acid (DA) in seawater was developed, based on a magnetic solid-phase extraction (MSPE) followed by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS). Five kinds of ferrite magnetic nanospheres (MFe2O4; M=Fe, Co, Ni, Cu and Zn) were prepared and first used as sorbents for MSPE of DA and ...

For the past decade, scientists have been toying with the notion of encapsulating medicine in microscopic balls. These so-called nanospheres could travel

sundoc Migration; Titel: Lipid nanodispersions as drug carrier systems, Verfasser: Jores, Katja, 2004 ; Halle, Saale : Universitäts- und Landesbibliothek

Reports: Goods and services imports and exports for June, weekly mortgage applications. Local earnings: CF Industries Holdings Inc., FreightCar America Inc., InnerWorkings Inc., Integrys Energy Group Inc., John Bean Technologies Corp., Manitex International Inc., Middleby Corp., Mondelez International Inc., MYR Group Inc., Nanosphere Inc., SP Plus Corp., Middleby Corp., Wells-Gardner Electronics Corp.. Other earnings: AOL Inc., Brookdale Senior Living Inc., Chrysler Group LLC, Dynegy Inc., MillerCoors LLC, Molson Coors Brewing Co., Roundys Inc., Ralp Lauren Corp., Viacom Inc., and others ...

Mission Workshop has some awesome apparel. I gotta get me some of these!! Check them out HERE!. The Division chino is designed to be hard wearing and long lasting. Constructed using Swiss-made Schoeller®-Dryskin fabric with Nanosphere® water repellent treatment. This durable 4-way stretch nylon fabric is engineered to provide breathability and moisture management in addition to wind and water repellency. All waist sizes feature a 34 inseam.. ...

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Children Appropriate studies have not been performed on the relationship of age to the effects of ketamine injection in children younger than 16 years of age. Safety and efficacy have not been established. Older adults Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ketamine injection in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or ...

It is very important that you take leucovorin exactly as directed , especially when it is being taken to counteract the harmful effects of cancer medicine. Do not miss any doses. Also, it is best to take the doses at evenly spaced times day and night. For example, if you are to take 4 doses a day, the doses should be spaced about 6 hours apart. If this interferes with your sleep or other daily activities, or if you need help in planning the best times to take your medicine, check with your health care professional. Do not stop taking leucovorin without checking with your doctor. It is very important that you get exactly the right amount. Dosing- The dose of this medicine will be different for different patients. Follow your doctors orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the ...

Neostigmine injection is also used to prevent or treat certain kidney or intestinal problems. This medicine is also given after surgery to help reverse the effects of certain types of medicines that have been used to relax the muscles. This medicine is available only with your doctors prescription. This product is available in the following dosage forms:. ...

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.. ...