Researchers first described Mycobacterium xenopi in 1959 after isolating it from skin lesions of the South African toad Xenopus laevis. M xenopi, a slow-growing, nontuberculous mycobacterium, is often considered to be a saprophyte or an environmental contaminant.

Eighteen isolates of a nonchromogenic, slowly growing, non-tuberculous species of the genus Mycobacterium were cultured from respiratory specimens obtained over the last eight years from 17 patients in the Netherlands. These isolates were grouped because they revealed a unique 16S rRNA gene sequence and were related to Mycobacterium xenopi. None of the 17 patients met the American Thoracic Society diagnostic criteria for non-tuberculous mycobacterial disease, which distinguishes the novel isolates from the related species, M. xenopi. A polyphasic taxonomic approach, including identification by biochemical and phenotypical analysis, hsp65 gene sequencing and PCR restriction enzyme pattern analysis, and sequence analyses of the rpoB gene and 16S23S internal transcribed spacer supported the separate species status of the novel isolates. The name Mycobacterium noviomagense sp. nov. is proposed for the novel strains. The type strain is NLA000500338T (=DSM 45145T=CIP 109766T). A more distinctive ...

|jats:p|In this study, we show that about 20% of the septating |jats:italic|Mycobacterium smegmatis |/jats:italic|and|jats:italic| Mycobacterium xenopi|/jats:italic| cells in the exponential phase populationdivideasymmetrically, with an unusually high deviation (17 ± 4%) in the division site from the median, to generate short cells and long cells, thereby generating population heterogeneity. This mode of division is very different from the symmetric division of themajority (about 80%) of the septating cells in the |jats:italic|Mycobacterium smegmatis|/jats:italic|, |jats:italic|Mycobacterium marinum|/jats:italic|, and |jats:italic|Mycobacterium bovis|/jats:italic| BCG exponential phase population, with 5-10% deviation in the division site from the mid-cell site, as reported by recent studies. The short cells and the long cells further grew and divided to generate a population. We speculate that the generation of the short cells and the long cells through the highly deviated asymmetric divisionin the

Rheumatology Web (Univ. of Colorado) www.UCHSC.edu/sm/rheum Arthrite infectieuse, Os maladie infectieuse. L antibioth rapie comme adjuvant dans le traitement des infections ost o-articulaires www.cps.ca/francais/enonces/ID/id94-10.htm. Les infections bact riennes ost o-articulaires (en dehors des infections mycobact ries) www.sante.ujf-grenoble.fr/SANTE/mmi/mmi_franc/CONFCONS/Inf-os.htm. Recommandations pour le diagnostic et le traitement des infections ost o-articulaires Mycobacterium xenopi www.ccr.jussieu.fr/cclin/xenowww.html. Arthrite r actionnelle. L arthrite post-streptococcique www.cps.ca/francais/enonces/ID/id95-05.htm. Articulation genou. Conf rence de consensus de l Andem sur l arthroscopie du genou www.upml.fr/andem/cs1.htm. Canal carpien syndrome. Strat gie des examens paracliniques et indications th rapeutiques dans le syndrome du canal carpien www.anaes.fr/ Cliquez ensuite sur Publications puis s lectionnez le classement par Titres ou par Sp cialit s. Cellulalgie ...

GPL X-IIb glycopeptidolipid: a serine-containing GPL isolated from Mycobacterium xenopi strain NCTC 10042; structure in first source

Looking for online definition of M. xenopi in the Medical Dictionary? M. xenopi explanation free. What is M. xenopi? Meaning of M. xenopi medical term. What does M. xenopi mean?

Results Data was obtained from 74 new isolations, with a total of 11 different species of NTM identified. Patients presenting had a median age of 68 and a range of 8-88 years. 39(53%) were female and 46 (62%) were one-off isolates. M. Avium-intracellulare (MAI) was the most frequently reported isolate (42 cases, 57%) followed by M. Chelonae (8, 11%) and M. Xenopi (6, 8%). The majority (68, 92%) of isolates were pulmonary with 45(66%) of these found in standard sputum culture. Most frequently recorded co-morbidities were bronchiectasis (35 cases, 47%) and COPD (20, 27%). Of the total of 74 cases only 24 (32%) had received treatment by the time of our survey. The overall rates for eradication and subsequent relapse in those treated patients were 50% and 25% respectively for the total population and 57% and 38% for those with MAI. At completion of the study the mortality rate within 2 years of the first positive sample was 18%.. ...

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Mycobacterium celatum has been shown to cause disease in immunocompromised patients. We report a case of serious pulmonary infection caused by M. celatum in an apparently immunocompetent patient and review the characteristics of two other reported cases. Clinical and radiologic symptoms and signs included cough, malaise, and weight loss associated with cavitary lesions and pulmonary infiltrates. Although M. celatum is easy to detect in clinical specimens by liquid and solid media, it may be misidentified as a member of the M. tuberculosis complex or as M. xenopi. M. celatum pulmonary infection appears to respond to antimycobacterial chemotherapy, particularly with clarithromycin ...

Mycobacterium celatum has been shown to cause disease in immunocompromised patients. We report a case of serious pulmonary infection caused by M. celatum in an apparently immunocompetent patient and review the characteristics of two other reported cases. Clinical and radiologic symptoms and signs included cough, malaise, and weight loss associated with cavitary lesions and pulmonary infiltrates. Although M. celatum is easy to detect in clinical specimens by liquid and solid media, it may be misidentified as a member of the M. tuberculosis complex or as M. xenopi. M. celatum pulmonary infection appears to respond to antimycobacterial chemotherapy, particularly with clarithromycin.

SPARKS, Md., June 17 /PRNewswire/ -- Launch of BD BACTEC™ MGIT™ 320 System Expands TB Detection Worldwide. New, Smaller Capacity System Designed for...

Background: Accurate active tuberculosis (TB) diagnosis remains a challenge in clinical practice, especially in HIV infected patients. The aim of the study was to determine the serum markers that are associated with pulmonary Mycobacterium tuberculosis among HIV infected febrile individuals. Methods: The study compared HIV infected people with and without pulmonary tuberculosis and asymptomatic HIV infected individuals for inflammatory makers CRP and leptin levels, and the activation markers IP 10 and β2 microglobulin. Markers were tested on previously collected frozen serum samples. Serum markers CRP, Leptin and β2- microglobulin were measured using the enzyme-linked immunosorbent assays in 20 cases with pulmonary Mycobacterium tuberculosis, 20 suspects (control1) with B symptoms but without Mycobacterium tuberculosis and 20 (control 2) asymptomatic HIV infected individuals. The IP 10 was measured using the Bio-plex Pro assay. The assays were performed according to the manufacturers‟ ...

Introduction: The epidemiology of nontuberculous mycobacteria (NTM) disease remains largely unknown in Greece.. Methods: We investigated the characteristics of patients under treatment for NTM disease for the first time in Greece, for the time period 2004-2013.. Results: Out of 58 cases (27 men and 31 women, mean age±sd: 58.93±12.55 years), one patient suffered from skin (M. marinum) and the rest form pulmonary disease. Fifty patients were of Greek origin and 8 were immigrants. M. avium complex (MAC) was the leading cause of NTM disease (35 cases, 60.34%: M. avium 16, M. intracellulare 16), M. kansasii ranked second with 8 cases (13.79%) whereas RGM presented with a relative frequency of 10.34%. The rest of NTM comprised an additional 15.53% (4 M. malmoense, 2 M. xenopi, 1 M. celatum, 1 M.lentiflavium, 1 M. marinum). Cavitation was present in 40 patients (69%) and 20 nodular bronchiectatic pattern in 18 (31%). All patients were HIV negative, 30 suffered from previously known bronchiectases, 16 ...

Once a terminal illness, HIV is now considered a chronic disease due to the advances in highly active antiretroviral treatment (HAART).

Overview The advent of highly active antiretroviral treatment has not diminished the need for palliative care for people living with HIV/AIDS. In fact, because of new treatments, fewer patients are d

Mitochondrial DNA (mtDNA) was assessed by Real-Time Polymerase Chain Reaction (RT-PCR) in peripheral blood mononuclear cells (PBMCs) of 13 perinatally-HIV-infected pediatric patients, who underwent planned treatment interruption (PTI). MtDNA was measured at the time of PTI and 12 months later. A sequence of a highly conserved mtND2 gene and a fragment of the nuclear-coded housekeeping 18SrRNA gene were amplified separately. Changes in mtDNA amount were expressed as the ratio of ND2 mtDNA with respect to 18SrRNAnDNA. ...

(2014) Min, Amlani. Case Reports in Pulmonology. A 66-year-old male presented with chest pain, malaise, generalized weakness, and weight loss. He had been receiving etanercept injection for rheumatoid arthritis. Chest X-ray revealed a right upper lobe mass. Chest computed tomography (CT) showed ...

The purpose of this study is to try a known antiretroviral combination in HIV- infected children with only one intake a day, in order to simplify the prescription and improve adherence to treatment. This is what is called a phase II clinical trial, only recruiting and following a small number of children (50) during one year to evaluate the quantity of drug in the blood just before it is taken and one to three hours after it is taken. The other important objective is to study the tolerance of drugs in that mode of prescription of the triple combination ...

The purpose of this study is to try a known antiretroviral combination in HIV- infected children with only one intake a day, in order to simplify the prescription and improve adherence to treatment. This is what is called a phase II clinical trial, only recruiting and following a small number of children (50) during one year to evaluate the quantity of drug in the blood just before it is taken and one to three hours after it is taken. The other important objective is to study the tolerance of drugs in that mode of prescription of the triple combination ...

We assess long-term changes in lipid levels in human immunodeficiency disease- (HIV-) infected patients undergoing highly active antiretroviral treatment (HAART) and their association with diabetes mellitus (DM) and thyroid dysfunction. We observed changes in the levels of total cholesterol (TC) and total triglyceride (TG) of 63 HIV-infected patients in the 6 years from starting HAART and analyzed correlations between relevant parameters. TC levels of patients with normal baseline TC levels as well as those diagnosed with DM or impaired fasting glucose (IFG) increased significantly (|svg xmlns:xlink=http://www.w3.org/1999/xlink xmlns=http://www.w3.org/2000/svg style=vertical-align:-0.0498209pt id=M1 height=8.68572pt version=1.1 viewBox=-0.0498162 -8.6359 12.5089 8.68572 width=12.5089pt||g transform=matrix(.013,0,0,-0.013,0,0)||path id=g113-81 d=M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243

As a result of the increased incidence of osteopenia and osteoporosis in HIV-infected patients, numerous publications have suggested that there may be a link between bone metabolism alterations and HIV infection. The early bone loss seen in these patients was initially attributed to the use of highly active antiretroviral treatment (HAART) that included protease inhibitors. Recent studies, however, have suggested that it may be a direct consequence of the viral infection on bone metabolism, persistent activation of pro-inflammatory cytokines (TNFa), or altered vitamin D metabolism secondary to the virus, combined with subsequent factors (e ...

به‌دلیل افزایش بیماری‌های نقص ایمنی در دهه‌های اخیر، مایکوباکتریوم‌های غیر توبرکلوزیس که پیش‌تر تنها به‌عنوان مایکوباکتریوم‌های محیطی شناخته می‌شدند، به‌عنوان پاتوژن‌های مهمی مطرح گردیده‌اند. در این مطالعه، تعداد 85 نمونه آب از منابع مختلف اصفهان برای بررسی وجود آلودگی به مایکو باکتریوم‌های محیطی تهیه و کشت داده شد و از ویژگی‌های فنوتیپیک برای تعیین گونه استفاده گردید. از مجموع 85 نمونه آب از منابع مختلف، 7/24 درصد دارای یک گونه NTM بود. از21 گونه شناسایی شده، مایکوباکتریوم فورچوئیتوم با فراوانی نسبی 8/23 درصد (5مورد)، م. اسمگماتیس 3/14 درصد (3مورد)،