Guanylin and uroguanylin are peptides that activate guanylyl cyclase C (GC-C) receptors in the intestine and kidney, which causes an increase in the excretion of salt and water. The Spinifex hopping mouse, Notomys alexis, is a desert rodent that can survive for extended periods without free access to water and it was hypothesised that to conserve water, the expression of guanylin, uroguanylin, and GC-C would be down-regulated to reduce the excretion of water in urine and faeces. Accordingly, this study examined the expression of guanylin, uroguanylin, and GC-C mRNA in Notomys under normal (access to water) and water-deprived conditions. Initially, guanylin and uroguanylin cDNAs encoding the full open reading frame were cloned and sequenced. A PCR analysis showed guanylin and uroguanylin mRNA expression in the small intestine, caecum, proximal and distal colon, heart, and kidney. In addition, a partial GC-C cDNA was obtained and GC-C mRNA expression was demonstrated in the proximal and distal ...
The cauda epididymidis, with its relatively cool temperature (32-35 degrees C), is considered to be the main site of sperm storage in male mammals. However, in the adult male spinifex hopping mouse, Notomys alexis, similar numbers of spermatozoa are found in the vas deferens to those in the cauda epididymidis. The present study shows that, unlike in the laboratory mouse in which spermatozoa of the vas deferens are found mainly in the epididymal region of the duct, spermatozoa in the hopping mouse are localized mainly to the middle and urethral regions of the vas deferens which lies in the inguinal and lower abdominal region of the body cavity. After ligation of the vas deferens close to its connection with the epididymis, many spermatozoa in the vas deferens retain the potential for motility for up to 2 weeks, indicating that the viability of spermatozoa is not compromised by being restricted to core body temperature. This urethral region of the vas deferens, in which spermatozoa reside, has a ...
Dobrava-Belgrade virus (DOBV), also known as Dobrava virus, is an enveloped, single-stranded, negative-sense RNA virus species of Old World Orthohantavirus. It is one of several species of Hantavirus that is the causative agent of severe Hantavirus hemorrhagic fever with renal syndrome. It was first isolated from yellow-necked mice (Apodemus flavicollis) found in Dobrava Village, Slovenia, Yugoslavia. It was subsequently isolated in striped field mice in Russia and other parts of Eastern Europe. It has also been found in Germany but the reservoir host there is unknown. Dobrava virus and the variants of Dobrava-Belgrade virus have been found in the Yellow-necked mouse [(Apodemus flavicollis) virus genotype Dobrava], the Striped field mouse [(Apodemus agrarius) virus genotype Kurkino] and Black Sea field mouse [(Apodemus ponticus) virus genotype Sochi]. The fatality rate is 12%, making Dobrava virus the most life-threatening hantavirus disease in Europe. Variant DOBV genotypes have different ...
ENGLISH ABSTRACT: Within southern Africa, the widely distributed four-striped mouse Rhabdomys is parasitized by, amongst others, the host-specific ectoparasitic sucking louse, Polyplax arvicanthis. The present study investigated this parasite-host association from a phylogenetic and phylogeographic perspective utilizing mitochondrial and nuclear DNA markers. The findings support the existence of four species within Rhabdomys (three distinct lineages within the previously recognized arid-adapted R. pumilio and the mesic-adapted R. dilectus). These species have distinct geographic distributions across vegetational biomes with two documented areas of sympatry at biome boundaries. Ecological niche modelling supports a strong correlation between regional biomes and the distribution of distinct evolutionary lineages of Rhabdomys. A Bayesian relaxed molecular clock suggests that cladogenesis within the genus coincides with paleoclimatic changes (and the establishment of the biomes) at the ...
Nowak, R. 1999. Walkers Mammals of the World, 6th Edition. Baltimore and London: The Johns Hopkins University Press. Packer, C. 1983. Demographic changes in a colony of Nile grassrats (Arvicanthis niloticus) in Tanzania. Journal of Mammalogy, 64(1): 159-161. Panagiotakopulu, E. 2004. Pharaonic Egypt and the origins of the plague. Journal of Biogeography, 31: 269-275. Rabiu, S., R. Rose. 1997. A quantitative study of diet in three species of rodents in natural and irrigated savanna fields. Acta Theriologica, 42(1): 55-70. Rabiu, S., R. Rose. 2004. Crop damage and yield loss caused by two species of rodents in irrigated fields in northern Nigeria. International Journal of Pest Management, 50(4): 323-326. Refinetti, R. 2004. The Nile Grass Rat as a Laboratory Animal. Lab Animal, 33(9): 54-57. Rosevear, D. 1969. London: Trustees of the British Museum (Natural History). Sarra, S., D. Peters. 2003. Rice yellow mottle virus is Transmitted by Cows, Donkeys, and Grass Rats in Irrigated Rice Crops. Plant ...
Read "Genetic variation and differentiation in striped field mouse Apodemus agrarius inferred from RAPD-PCR analysis, Russian Journal of Genetics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
We studied temporal partitioning between two spiny mouse species that coexist in hot rocky deserts in the Middle East: nocturnal common spiny mice (Acomys cahirinus) and diurnally active golden spiny mice (A. russatus). Although A. russatus is diurnally active, it retains the physical activity and body temperature rhythms of nocturnal mammals. We studied the two species in four 1000-m 2 enclosures at Ein Gedi, Israel: two experimental enclosures with A. russatus kept alone, and two controls with individuals of both species kept together. We monitored activity with Sherman traps and by studying foraging microhabitat use and efficiency using giving-up densities (GUDs) in food trays. The trays contained broken sunflower seeds mixed in local soil and placed in three micro- habitats: under boulders, between boulders, and in the open. Trapping revealed that, in the absence of A. cahirinus, the usually diurnal A. russatus was active both day and night. However, during the day A. russatus still foraged in
To clarify the presence of lymphocytic choriomeningitis virus (LCMV) in Spain, we examined blood and tissue specimens from 866 small mammals. LCMV RNA was detected in 3 of 694 wood mice (Apodemus sylvaticus). Phylogenetic analyses suggest that the strains constitute a new evolutionary lineage. LCMV antibodies were detected in 4 of 10 rodent species tested.
Alexis Bellino Body Statistics, Measurements, Waist, Hips, Bust, Bra Size, Weight, Height, Figure Shape, Dress And Feet Size. Alexis Bellino Weight: 128 lbs (58 kg). Alexis Bellino Height: 5′ 9″ (1.75 m). Alexis Bellino Measurements: Unknown. Alexis Bellino Bra Size/Breast Size: Unknown. Alexis Bellino Bra Cup Size: Unknown. Alexis Bellino Shoe Size/Feet Size: 10 (US). Alexis Bellino Dress Size: 4 (US). Alexis Bellino Star Sign: Capricorn. Alexis Bellino Net Worth: $500000. Date Of Birth: 19 January 1977. Birth Place: Hannibal, Missouri, USA. Nationality American. Spouse: Jim Bellino (m. 2005). Children: James Bellino, Melania Beino, Mackenna Belino. Alexis Bellino was born in the small town of Hannibal, Missouri. She graduated from Hannibal High School in 1995.. ...
When an animal is injured, immune cells such as macrophages rush to the wounded site to clear debris and help repair the damage. Macrophages come in different forms and subtypes, and express different protein markers on their surface, depending on where in the body they reside. Few mammals can completely renew or regrow a damaged tissue - a process known as tissue regeneration. Instead, humans and most other mammals repair injuries by producing scar tissue, which has different properties compared to the original tissue it replaces. One exception is the African spiny mouse (Acomys cahirinus), which, unlike other rodents studied, can regrow skin and fur, nerves, muscles, and even cartilage. It has been shown that in highly regenerative animals such as salamanders and zebrafish, macrophages are necessary to initiate tissue regeneration. Documented cases of tissue regeneration in mammals are rare and therefore less understood. Until now, it was not clear why two species as closely related as spiny ...
Purpose : Controversy exists on the pathological events initiating retinal complications in response to prolonged hyperglycemia. High blood sugar causes an increase in glycated hemoglobin, which compromises oxygen supply to the tissues. Due to the high metabolic activity of the outer retina, and its sensitivity to acute changes in oxygen and energy flux, mitochondrial dysfunction has been proposed as a potential early indicator of diabetic retinopathy. We hypothesize that mitochondrial abnormalities will be detected in the retina prior to hyperglycemia onset in the Nile grass rat model of spontaneous slow progressing Type 2 diabetes. Methods : Nile grass rats were fed standard rodent chow (Prolab 2000) or a high fibre low fat diet (Mazuri Chinchilla). Retina and retinal pigment epithelium (RPE) were studied at 2, 6, and 18 months. Following euthanasia and enucleation, tissues from individual animals were isolated, weighed, and homogenized. Function of the distinct respiratory system complexes ...
Karyotypes of four Chinese species of field mice of the genus Apodemus were examined, including Apodemus chevrieri (diploid chromosome number, 2n=48, fundamental number of autosomal arms, FNa=56), A. draco (2n=48, FNa=48), A. ilex (2n=48, FNa=48), and A. latronum (2n=48, FNa=48). Karyotypes of A. chevrieri, A. draco, and A. ilex are reported here for the first time, providing useful information for their species taxonomy. Determining the karyotypes of all species of Apodemus in Asia, both in this and previous studies, provides a solid overview of the chromosome evolution and species differentiation of the genus in East Asia. In addition to allopatric speciation, chromosome rearrangements likely played an important role in the formation of the four Apodemus species groups as well as speciation within each group in East Asia. For example, increased centromeric heterochromatin in A. latronum may have contributed to the post-mating reproductive isolation from the A. draco-A. ilex-A. semotus clade ...
All animals face at least occasional problems of orientation. Especially for vertebrates, this can involve periods of almost continuous decisions. Much remains unknown about the processes involved in spatial orientation, and the behaviour patterns through which navigation is achieved. As a general model, mammals are thought to use fixed external cues as points of reference during their movements [1]. This model holds that an individuals spatial references are updated, with respect to the array of fixed land-marks, so that it is able to return to its refuge, feeding places, or other places of interest. This system (termed path integration) is generally thought to be especially important to central-place foragers, which sometimes have to return home even in the absence of external cues [1]. Return by path integration is, however, never precise and, depending on the species, systematic errors can occur in navigation. Indeed, it remains possible that path integration and landmark guidance are ...
Alexis Arquette, transgender character actress and brother of David, Rosanna, Richmond and Patricia Arquette actors, died early Sunday in Los Angeles. She was 47 years old and surrounded by family who serenade Starman David Bowie, his brothers said in a statement.. "Alexis was a brilliant artist and painter, a singer, an artist and an actor," said his brothers and sisters. "We have learned what the real value is through watching their way of life as a trans woman arrived to discover the only truth -. That love is everything.". They added: "We are comforted by the fact that Alexis came into our family and was our brother and our sister then, and she gave us so much love We will love always, Alexis know we were the lucky ones…". Robert Alexis Arquette was born in Los Angeles in 1969, and was a performer from a young age, appearing in a music video of the tubes Shes a beauty for 12 years.. A versatile performer, Arquette great opportunity came in the 1989 adaptation of Last Exit to Brooklyn, in ...
The multimammate rat, Mastomys natalensis Smith 1834, is a dominant species in agro-ecosystems in Sub-Saharan Africa, but adapts quickly to changes in non-agricultural landscape, particularly woodlands and forests. In this study we report on reproduction and population dynamics of M. natalensis in deforested high elevation localities in the Usambara Mountains, north-east Tanzania. We conducted Capture-Mark-Recapture studies in 2002-2004, and established that reproduction of M. natalensis takes place in the extended wet season between February and June, and the population density peaks in June-August. Reproduction cease in July to January and population density drops from July onwards. Reproduction and population density fluctuations are linked to the duration and amount of rainfall. In years when rainfall was below average and the wet season was short, the population density was significantly lower (below 10 animals/ha and 60 animals/ha in 2003 and 2004 respectively, compared to ,100 animals/ha ...
A group at Monash University has been using the spiny mouse in studies of fetal programming and sex-dependent effects of glucocorticoids on placental development (here). The spiny mouse holds great promise as a new model for placental and fetal development. Moreover, its potential for studies in a quite different area, tissue regeneration (here), means it is likely to be come more widely available as a laboratory animal. ...
Alexis Bledel Fuses With Zach Gilford Costars Alexis Bledel and Zach Gilford promote their new movie Post Grad at Fuse Networks new The Pop Show on Thursday (August 20) in New York City. Alexis,…
Linnaeus, C. 1758. Systema Naturae per regna tria naturæ, secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Tomus I. Editio decima, reformata. Holmiæ: impensis direct. Laurentii Salvii. i-ii, 1-824 pp doi: 10.5962/bhl.title.542: page 62. ...
We describe Halmaheramys bokimekot Fabre, Pagès, Musser, Fitriana, Semiadi & Helgen gen. et sp. nov., a new genus and species of murine rodent from the North Moluccas, and study its phylogenetic placement using both molecular and morphological data. We generated a densely sampled mitochondrial and nuclear DNA data set that included most genera of Indo-Pacific Murinae, and used probabilistic methodologies to infer their phylogenetic relationships. To reconstruct their biogeographical history, we first dated the topology and then used a Lagrange analysis to infer ancestral geographic areas. Finally, we combined the ancestral area reconstructions with temporal information to compare patterns of murine colonization among Indo-Pacific archipelagos. We provide a new and comprehensive molecular phylogenetic reconstruction for Indo-Pacific Murinae, with a focus on the Rattus division. Using previous results and those presented in this study, we define a new Indo-Pacific group within the Rattus ...
At Alexis house, Alexis glanced out the window when she heard the doorbell, and she saw Julian on the porch. She took a fortifying breath then went to the door. Alexis warned Julian that shed been working on an important case, but he entered the house and asked if she had time for another court case. Alexis refused to represent him, but he clarified that he wanted her to be a witness for the defense. Alexis declined because her suspension had only recently been lifted, and she had no intention of jeopardizing her career again by perjuring herself on the stand. Julian assured her that she would only be expected to tell the truth, but she argued that hed go to jail if she did. Julian disagreed because Alexis had heard his sister Olivia threatening him on the bridge the night Olivia had kidnapped Alexis. Instead of following Olivias orders to kill Alexis, he had shot off Alexis handcuffs and taken a bullet for her so she could escape. Alexis explained that any lawyer could easily tear apart a ...
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Alexis Hospital Nagpur is an international standard multispecialty tertiary hospital with comprehensive outpatient and inpatient facilities with a capacity of 200 beds and 35 doctors.
The novel Fifteen Dogs by André Alexis won the 2015 Giller Prize. The premise is a bet between Apollo and Hermes: if dogs were given language, would they be any happier than humans? What follows is a whimsical, dark and penetrating tour of ideas -- about consciousness, time, belonging, mortality, art and love. André Alexis talks to host Paul Kennedy about the philosophical underpinnings of his prize-winning book -- featuring readings by the author himself.
If you notice, Alexis makes it clear that it was her decision to leave - even going so far as to say she turned down a very generous offer from Bravo. This contradicts a September 18 report from E! news:. "She wasnt invited back," a source tells E!. "The crew was tired of her complaining and diva ways. They were also tired of her fame-seeking husband.". Tamra Barney also seemed suspicious of Alexis, having this Twitter conversation with @CelebRealityGal on September 18:. CELEBREALITYGAL: @usweekly is reporting that @AlexisBellino is not retuning to RHOC! Thoughts??. TAMRA: @CelebRealityGal cheers to that. But she should have been honest. CELEBREALITYGAL: @TamraBarney What do you think the real reason behind her departure is?. TAMRA: @CelebRealityGal who leaves a successful show?. CELEBREALITYGAL: @TamraBarney Not me.. So I am digging but are you saying it was Jims idea or that she wad [sic] fired?. TAMRA: @CelebRealityGal lets just say the story I read and what I was told does not ...
Noah Centineo and Alexis Ren are fast becoming our new fav celeb couple (sorry Halsey and Evan Peters). On Sunday, Alexis attended an event for official hot girl brand Revolve where the model COULD NOT stop talking about how much she loves her boyfriend Noah.
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Neuropathic pain is a large unmet medical need because the currently available drug treatments either lack efficacy and/or have dose-limiting side-effects. Due to this, my patent-protected angiotensin II type 2 (AT2) receptor antagonist technology - encompassing a potentially first-in-class novel analgesic for the treatment of often intractable neuropathic pain conditions - attracted initial seed capital investment from the Symbiosis Group, GBS Ventures and Uniseed Pty Ltd. In total $3.25M was raised and in mid-2005 the spin-out company, Spinifex Pharmaceuticals was formed by UniQuest Pty Ltd, the main commercialisation company of The University of Queensland. The raison detre for Spinifex Pharmaceuticals at that time was to develop AT2 receptor antagonists as efficacious, well-tolerated first-in-class novel analgesics for relief of neuropathic pain. In 2006, I discovered that AT2 receptor antagonists also alleviated chronic inflammatory pain in a rat model. This was quite unexpected as ...
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Arsenal manager Arsene Wenger describes Alexis Sanchez as a fighter and a classy player after the Chilean scored a hat-trick in the 5-1 Premier League win at West Ham.
By Genevieve Grandcourt. A very evident disadvantage under which medical science has labored has been the impossibility of watching the chemical process set in motion by substances introduced into the body. For this reason various experimenters, from time to time, have attempted to "grow tissues" artificially, in such manner that their development, functions, and decay-under both healthy and diseased conditions-might be studied under the microscope. The only way in which this could be done would be to take a piece of living tissue from the body, and cause its cells to multiply; tissue being made up of an aggregation of cells.. Science has failed to produce a single living cell, that is, a cell which will undergo the process of nuclear division (growth) which is the prime condition of its being; and it seemed equally impossible to cause a cell already living to undergo the same process if deprived of the circulation of the blood. Therefore, when in 1910 it was announced that Dr. Alexis Carrel ...
Texan Alexis Hefley, founder and president of Empower African Children, has spent two decades working to improve the lives of orphans and other children in E...
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Study Hematology -- cancer translocations and cell markers flashcards from Alexis San's class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Alexis "Lex" Luthor was born into a middle-class family household supported by his absentee father, a traveling salesman. Because his father was rarely around, it fell to Lex to take care of the family at home and cultivate the familys fields. However, in spite of his humble farmboy lifestyle...
Help people like Alexis, who needs blood transfusions every 4 weeks to help stop her suffering a stroke due to her Sickle Cell disease.
Travel may be impossible at times Sunday night into Monday night with winds gusting to 35 to 40 miles per hour or more at times. Besides these two different track possibilities, the timing of the changeover from rain to wintry mix to snow is crucial. "Alexis is a player that becomes more than a player because of his multi-functionality", he added. There have been a lot of young players, hes managed them and theyve done very well.. "I would rather encourage a club to push more on the quality of our youth work, which we are doing, than go into a way where its only about millions and not so much about values".. Could he perform better with us? "I repeat, to be Manchester United manager is an honour every day and I am really happy". Maybe. Could he also have given more to try to adapt to us?. "Ive known him for many, many years, I was with him in Italy at Udinese, in Spain, when he was at Barcelona, in England, when he was at Arsenal, so our careers were nearly made in the same countries ...
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Hello, My name is Alexis! I am 21 years old and just moved to Beacon! I attend Dutchess Community College and live with my boyfriend and our Rescu...
Asthma doesnt stop 12-year-old Alexis from doing the things she loves. The key? Listening to her doctor and taking her medicines. Here, she talks about how she balances asthma care with home life, school, and swimming.. ...
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Since Alexis was a little girl shes passionately pursued science and art, as a college student shes combining both ends of the education spectrum.
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H. Jay Ginns, Janet Ginns and Robert Ginns, Plaintiffs-appellees, v. Alexis Towle and Nancy Towle, Defendants-appellants, 361 F.2d 798 (2d Cir. 1966) case opinion from the US Court of Appeals for the Second Circuit
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