Final Patient Enrolled In International Trial of MicroVention, Inc.s HydroCoil(R) Embolic System - read this article along with other careers information, tips and advice on BioSpace
Germanys Curetis said this week that it has begun an additional, prospective, multicenter clinical trial of its Unyvero P50 Pneumonia test to demonstrate its clinical and health economic value.
The purpose of this report is to describe the state of imaging techniques and technologies for detecting response of brain tumors to treatment in the setting of multicenter clinical trials. Within currently used technologies, implementation of standardized image acquisition and the use of volumetric …
Pietsch T, Schmidt R, Remke M, Korshunov A, Hovestadt V, Jones DT, Felsberg J, Kaulich K, Goschzik T, Kool M, Northcott PA, von Hoff K, von Bueren AO, Friedrich C, Mynarek M, Skladny H, Fleischhack G, Taylor MD, Cremer F, Lichter P, Faldum A, Reifenberger G, Rutkowski S, Pfister SM. Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort. Acta Neuropathol. 2014 Jul; 128(1):137-49 ...
Objectives: To identify factors associated with good and poor recruitment to multicentre trials. Data sources: Part A: database of trials started in or after 1994 and were due to end before 2003 held by the Medical Research ...
Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-ll): A Phase III Randomized Multicenter Clinical Trial of Blood Pressure Reduction ...
PubMed journal article: A Randomized Multicenter Clinical Trial of RPH With the Simplified Milligan-Morgan Hemorrhoidectomy in the Treatment of Mixed Hemorrhoids. Download Prime PubMed App to iPhone, iPad, or Android
FedBizOpps the Way You Want It - Best listing of FedBizOpps notices, searches and subscriptions with free, on-line Archives back to 1995
Reference Guide for Academic Imaging Core Labs ASE is committed to enhancing the credibility and validity of echocardiography as a research and clinical tool. Academic imaging core labs, those labs that conduct centralized research analysis for multicenter clinical trials outside of the clinical scenario, are a crucial
Coimbra AJ, Rimola J, OByrne S, Lu TT, Bengtsson T, de Crespigny A, Luca D, Rutgeerts P, Bruining DH, Fidler JL, Sandborn WJ, Santillan CS, Higgins PD, Al-Hawary MM, Vermeire S, Vanbeckevoort D, Vanslembrouck R, Peyrin-Biroulet L, Laurent V, Herrmann KA, Panes J. Magnetic resonance enterography is feasible and reliable in multicenter clinical trials in patients with Crohns disease, and may help select subjects with active inflammation. Aliment Pharmacol Ther. 2016 Jan; 43: (1)61-72 ...
Intensivist Jeremy Cohen drills down on the thinking and value of using steroids in sepsis and the current evidence base. He also discusses a large international trial in progress to find some new answers to all the uncertainty.. ...
21, 2013, at the Orange County Convention Center, FL. The meeting showcases more than 5,000 abstracts and hundreds of lectures on the latest advances in GI rese
TY - JOUR. T1 - The albumin in acute stroke (ALIAS) multicenter clinical trial. T2 - Safety analysis of part 1 and rationale and design of part 2. AU - Ginsberg, Myron D.. AU - Palesch, Yuko Y.. AU - Martin, Renee H.. AU - Hill, Michael D.. AU - Moy, Claudia S.. AU - Waldman, Bonnie D.. AU - Yeatts, Sharon D.. AU - Tamariz, Diego. AU - Ryckborst, Karla. N1 - Copyright: Copyright 2011 Elsevier B.V., All rights reserved.. PY - 2011/1. Y1 - 2011/1. N2 - Background and Purpose-Enrollment in the Albumin in Acute Stroke (ALIAS) Trial was suspended in late 2007 due to a safety concern. We present the safety data of that Trial (Part 1) and the rationale for the design of Part 2. Methods-ALIAS Part 1 was designed to assess whether 25% albumin (ALB) started within 5 hours of stroke onset would confer neuroprotection in subjects with acute ischemic stroke and baseline National Institutes of Health Stroke Scale of ≥6. Exclusion criteria included recent or current congestive heart failure, myocardial ...
Although recent advances have been made in antiviral therapy against AIDS, there is currently no cure for AIDS. It is likely that ultimate control of the disease depends on the development of safe and effective vaccines against HIV.. Healthy, adult volunteers without identifiable high-risk behavior for HIV-1 infection are vaccinated. In phase 1, at each participating unit, four volunteers receive a dose of gp160 (12.5 mcg); two volunteers receive placebo. Volunteers are monitored 1 month before proceeding to the second phase. In phase 2, four volunteers receive gp160 (50 mcg); two volunteers receive placebo. Primary immunization and two booster immunizations at day 30 and day 180 are done in an outpatient setting. Volunteers are closely monitored for the first 2 weeks postimmunization (primary and boosters), and extensively followed for a minimum of 2 years. Volunteers may be offered an additional boost of the same preparation at 18 months. Per 07/28/92 amendment, 18 volunteers will receive 200 ...
TY - JOUR. T1 - Relationship between the MDS-UPDRS and Quality of Life. T2 - A large multicenter study of 3206 patients. AU - Skorvanek, Matej. AU - Martinez-Martin, Pablo. AU - Kovacs, Norbert. AU - Zezula, Ivan. AU - Rodriguez-Violante, Mayela. AU - Corvol, Jean Christophe. AU - Taba, Pille. AU - Seppi, Klaus. AU - Levin, Oleg. AU - Schrag, Anette. AU - Aviles-Olmos, Iciar. AU - Alvarez-Sanchez, Mario. AU - Arakaki, Tomoko. AU - Aschermann, Zsuzsanna. AU - Benchetrit, Eve. AU - Benoit, Charline. AU - Bergareche-Yarza, Alberto. AU - Cervantes-Arriaga, Amin. AU - Chade, Anabel. AU - Cormier, Florence. AU - Datieva, Veronika. AU - Gallagher, David A.. AU - Garretto, Nelida. AU - Gdovinova, Zuzana. AU - Gershanik, Oscar. AU - Grofik, Milan. AU - Han, Vladimir. AU - Kadastik-Eerme, Liis. AU - Kurtis, Monica M.. AU - Mangone, Graziella. AU - Martinez-Castrillo, Juan Carlos. AU - Mendoza-Rodriguez, Amelia. AU - Minar, Michal. AU - Moore, Henry P.. AU - Muldmaa, Mari. AU - Mueller, Christoph. AU - ...
Bevacizumab (Avastin) failed to improve survival in advanced melanoma when added to carboplatin and paclitaxel, results of a randomized, multicenter clinical trial showed.
Instructions for submitting data collection tools:. All data submissions should be entered through the EAST Multicenter Trial Committee website portal. Instructions can be found on the EAST website. The data collection sheet located under the Multicenter Trial Committee heading for this study can be utilized to record the data, and then the information transferred to the portal entry system. For any questions regarding this study, please contact the PI.. Questions? Please contact EAST Management Office at (312) 202-5616 or [email protected] ...
Intensivist Jeremy Cohen drills down on the thinking and value of using steroids in sepsis and the current evidence base. He also discusses a large international trial in progress to find some new answers to all the uncertainty.. ...
This study will assess the safety, tolerability, and pharmacokinetics in AML and high risk MDS patients with either wild type or mutated FLT3 using PKC4
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Study to demonstrate added value of Unyvero™ P50 pneumonia application in clinical routine -. Curetis AG today announced the start of an additional prospective, multicenter clinical trial of its marketed Unyvero™ P50 Pneumonia Application to demonstrate its clinical and health economic value.. The CE performance evaluation completed last year already demonstrated 81% sensitivity at 99% specificity for detecting pneumonia-causing pathogens. Following the market launch in April 2012, Curetis in 2013 presented data from more than 1,000 patient samples showing overall sensitivity of its pathogen panel of 80.6% at a specificity of 96% (ECCMID European Conference of Clinical Microbiology and Infectious Diseases, Berlin).[1]. The new multicenter study aims to establish real-world data on the health economic impact of fast, patient-near molecular testing and subsequent therapy adjustments (if necessary). It will be conducted in five leading European centers and will involve several hundred ...
As a squat, red-and-black robot nicknamed CHIMP gingerly pushed open a spring-loaded door a gust of wind swooped down onto the track at the Homestead-Miami Speedway and slammed the door shut, eliciting a collective sigh of disappointment from the audience.
Effective treatment of high-risk neuroblastoma (NB) remains a major challenge in pediatric oncology. planning by lysis of erythrocytes was examined revealing equivalent outcomes at an E:T percentage of 401. Optimal outcomes for CDC had been JNJ-38877605 found having a serum dilution at 18. For validation, both within-assay and inter-assay accuracy were established and coefficients of variant (CV) had been below 20%. Test quality following storage space at room temperatures (RT) demonstrated that sodium-heparin-anticoagulated bloodstream and serum are steady for 48 h and 96 h, respectively. Software of the bioassays to bloodstream examples of three chosen high-risk NB individuals treated with ch14.18/CHO (100 mg/m2) revealed GD2-particular increases in CDC (4.5C9.4 fold) and ADCC (4.6C6.0 fold) about day 8 compared to baseline, indicating assay applicability for the monitoring of multicenter clinical trials requiring sample shipment at RT for central lab analysis. Introduction Monoclonal ...
SODIUM-HF is a multicenter clinical trial in ambulatory patients with chronic HF to evaluate the efficacy of a low sodium containing diet on a composite clinical outcome composed of of all-cause mortality, cardiovascular hospitalizations and cardiovascular emergency department visits. The hypothesis of this study is that patients following a low-sodium containing diet will have fewer clinical events (fewer hospital readmissions or emergency department visits, longer survival) than those randomized to Usual Care ...
Health, ...New York City NY (May 19 2011) Researchers at the University of Flo...In addition the medical food UltraMeal PLUS 360 is 40 percent more li...The results of the multicenter clinical trial are published in the May... Chronic illness is draining our healthcare resources and keeping mill...,Breakthrough,medical,food,reverses,risk,of,heart,disease,and,diabetes,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
A breakthrough international trial of a new cancer drug has given researchers renewed hope in the fight against leukaemia, with one Melbourne doctor suggesting it could end traditional chemotherapy treatments for good.
TOTAL may not totally spell the end of routine manual thrombectomy with PCI, but it should make interventional cardiologists think twice about using it with STEMI patients. The large, international trial showed no clinical benefit and possible harm.
This single-arm, multicenter phase 2 trial will treat the patients who have relapsed or refractory stomach cancer with an infusion of the patients own T cells
The Paediatric Rheumatology INternational Trials Organisation (PRINTO) is a non governmental international network with the goal to facilitate and co-ordinate the development, of multi-centres, international clinical trials and/or outcome standardisation studies in children with paediatric rheumatic diseases.
The Paediatric Rheumatology INternational Trials Organisation (PRINTO) is a non governmental international network with the goal to facilitate and co-ordinate the development, of multi-centres, international clinical trials and/or outcome standardisation studies in children with paediatric rheumatic diseases.
Health, ...An international trial has provided surgeons with a formula which pred...Brain haemorrhage affects some 4 million patients a year worldwide and...David Mendelow Professor of Neurosurgery at Newcastle University and ...Professor Mendelow said: This study gives hope to patients at the tim...,Brain,haemorrhage,patients,offered,better,treatment,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Results At baseline all groups were comparable in their demographic, clinical and radiographic characteristics. One hundred twenty-seven pts completed the study. At 12 months there was no radiographic progression in the majority of pts (,75% in each group). Increase of the number of erosions and joint space narrowings was maximal in MTX group (mean, 35 and 80 respectively), and minimal in MTX-P group (mean, 12 and 20 respectively), p = 0.066. Slowing of disease progression with Lef was similar to MTX. There were no significant differences in radiological score between groups MTX-P and MTX-P-MP at 12 months Relative slowing of disease progression was noted in groups MTX-P and MTX-P-MP in comparison with MTX group (p = 0.08) but not with Lef group (p,0,1). Of note, among 20 pts with evident radiographic joint progression 9 pts had good clinical response according to EULAR criteria. RF and ACCP had no predictive value for the radiologic progression.. ...
Yoshiki Sawa, MD, PhD, discusses a large multicenter study in Japan demonstrating high survival rates in AMI cardiogenic shock patients receiving the Impella heart pump.
As part of the only U.S. prospective multicenter clinical trial to compare natural orifice translumenal endoscopic surgery (NOTES) to laparoscopy, surgeons at the University of California, San Diego School of Medicine have performed the trials first oral gallbladder removal.
http://www.nejm.org/doi/full/10.1056/NEJMoa1011205?viewType=Print.. This phase III, randomized, double-blind, placebo-controlled multinational trial of fixed-dose combination tenofovir disporoxil fumarate/emtricitabine orally once daily for the prevention of HIV acquisition in at-risk men who have sex with men was the first large-scale trial that demonstrated that daily oral preexposure prophylaxis (PrEP) with tenofovir disporoxil fumarate/emtricitabine is safe and efficacious, particularly with high rates of adherence. It led to the first US guidance on the role of PrEP in the prevention of HIV in high risk populations. ...
These findings suggest that the C-SSRS is suitable for assessment of suicidal ideation and behavior in clinical and research settings.
A COVID-19 vaccine is set to be the first from Australia to make international trials, with or without federal government backing, says developer.
In an analysis of deaths occurring during a large international trial of treatments for HIV-positive patients, researchers have found a strong association between markers of inflammation and coagulation and increased risk ...
Kalyoncu, A. F., Çöplü, L., Selçuk, Z. T., Emri, A. S., Kolaçan, B., Kocabaş, A., αkkoçlcu, A., Erkan, L., şahin, A. and Bariş, Y. I. (1995), Survey of the allergic status of patients with bronchial asthma in Turkey: a multicenter study. Allergy, 50: 451-455. doi: 10.1111/j.1398-9995.1995.tb01177.x ...
The purpose of this study is to determine if bempedoic acid (ETC-1002) added-on to ezetimibe therapy is effective and safe versus placebo in patients with
Maggie Bryans, Ph.D.. Principal Investigator. [email protected] 215.619.7335. Linda Rehfuss, Ph.D.. Co-PI and Co-Lead. [email protected] 215.504.8694. ...
Looking for something new? We hear you. Browse 43 TORONTO, ONTARIO WEST PARK HEALTHCARE CENTRE job listings from companies with openings that are hiring right now! Quickly find and apply for your next job opportunity on Workopolis. Compare salaries and apply for all the west park healthcare centre jobs in Toronto, Ontario
vintage (7) german scrap (5) gratitude (5) love (4) snow (4) solder (4) spring (4) wire wrapped (4) beads (3) gift (3) heart (3) necklace (3) pink (3) snow flakes (3) soldered (3) trees (3) turquoise (3) african turquoise (2) amazonite (2) bird of prey (2) black cat (2) breathe (2) broken (2) chaos (2) christmas (2) crash (2) divine inspiration (2) ephemera (2) etsy shop grand opening (2) faith (2) falcon (2) fish (2) flight (2) fountains (2) grateful (2) green (2) hawk (2) holly berry (2) home (2) illinois (2) inspiration (2) january (2) leaves (2) menieres disease (2) metformin (2) more snow (2) ombre glitter (2) orange (2) panic (2) peace (2) pennies from heaven (2) pond (2) roses (2) saint louis union station (2) sea shells (2) slippers (2) snow man (2) tie dye (2) treat (2) unique (2) winter blahs (2) xanax (2) 1900 (1) 1920 (1) 1930 (1) Thanksgiving (1) adore (1) alive (1) anemia (1) antique (1) antique camera (1) antique candle holder (1) antique quilt (1) apple head (1) arch (1) arf (1) ...
Research governance is the means by which the quality of research into social care services in Suffolk is assured and the rights of those involved protected.
The importance of unbiased comparative research trials to answer clinical questions that guide best treatment practices is unquestionable. Large multicenter clinical trials are critical for answering important clinical questions that cannot be answered by observational data. These studies depend on adequate recruitment from unbiased samples of patients from the population of interest. Investigators participating in such trials must also have clinical equipoise that the treatment under study may or may not be better than the standard treatments available. If such clinical equipoise does not exist, then recruitment will be biased and potentially delayed. In recent years, stroke clinical trials have struggled to enroll patients to acute trials for a variety of reasons, including narrow eligibility time windows and, most recently, to the growing list of available, although not necessarily safe or efficacious, therapies.. In January 2008, the US Food and Drug Administration cleared the second device ...
HIMALI™ is a brand that creates premium mountaineering apparel and gives back to the Nepali community.. The Himalaya are home to the 14 tallest peaks on the planet. It is where we go to push the limits of our mental and physical performance. These peaks are collectively known as the 14 Eight Thousand Meter Peaks.. These 14 peaks are represented within our logo, where the number 14 is encapsulated within the letter H. This is an everlasting reminder of our bottom line: to create quality gear that stands up to the worlds highest and harshest demands.. HIMALI™ is at K2. This Winter, an all Nepali team became the first to summit K2 in the Winter. They summited shoulder to shoulder, with everyone on this team listed as a holder of this first ascent.. Mingma G helped lead the historic K2 Winter expedition and today, we proudly announce his welcoming to our athlete team! His humble confidence, and bravery speaks volumes about where he can go and what he can accomplish.. Mingma Gyabu Sherpa was one ...
Purpose: Recent developments in rare-cell technology have led to improved blood-based assays that allow for the reliable detection, enumeration, and more recently, genomic profiling of circulating tumor cells (CTCs). We evaluated two different approaches for enumeration of CTCs in a prospective therapeutic study of patients with metastatic triple-negative breast cancer (TNBC). Experimental Design: The CellSearch system, a commercially available and U.S. Food and Drug Administration (FDA)-cleared assay for CTC enumeration, and IE/FC, an alternative method using EPCAM-based immunomagnetic enrichment and flow cytometry that maintains cell viability, were used to enumerate CTCs in blood of patients with metastatic TNBC. CTC numbers were assessed at baseline and 7-14d after initiation of therapy with cetuximab ± carboplatin in a Phase II multicenter clinical trial (TBCRC 001). Results: CTC numbers from two methods were significantly correlated at baseline (r=0.62) and at 7-14d (r=0.53). Baseline ...
Radiotherapy treatment (RT) after surgery for ductal carcinoma in situ (DCIS) has a major protective effect against recurrence more than 15 years later, according to the results of an international trial presented March 22 at the 8th European Breast Cancer Conference (EBCC-8).
American Family Physician has published an open-access set of articles and editorials that examine findings from a recent international trial of ovarian cancer screening.
Fingerprint Dive into the research topics of Results of a Multicenter Trial using the BTA Test to Monitor for and Diagnose Recurrent Bladder Cancer. Together they form a unique fingerprint. ...
Challenges in Undertaking a Multi-Center Prospective, Observational, Cohort Study in the Pediatric Oncology Population Conference Paper ...
Please return to our September 17, 2017 multi-site reference intervals discussion, and in particular to Heather DeVriess comment and question about a combined INR and reportable range. So many of us are grappling with multi-site services, George hopes our participants can provide some advice on this topic. Thank you.
Thank you for your interest in spreading the word on Stroke.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...
De HvA inspireert studenten om met creatieve oplossingen en duurzame innovaties aan de toekomst te werken; om vandaag te verbinden met morgen.
High sensitivity and specificity, plus insights for quantifying infections and identifying co-infections QIAGEN (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced the publication of a multicenter