Looking for online definition of Forssman antigen in the Medical Dictionary? Forssman antigen explanation free. What is Forssman antigen? Meaning of Forssman antigen medical term. What does Forssman antigen mean?

Looking for heterophile antibody test? Find out information about heterophile antibody test. heterophile agglutination test Explanation of heterophile antibody test

Looking for cytomegalovirus mononucleosis? Find out information about cytomegalovirus mononucleosis. A self-limited illness such as infectious mononucleosis, the main manifestation of which is fever; it is the only cytomegalovirus illness clearly described... Explanation of cytomegalovirus mononucleosis

Looking for online definition of chronic mononucleosis in the Medical Dictionary? chronic mononucleosis explanation free. What is chronic mononucleosis? Meaning of chronic mononucleosis medical term. What does chronic mononucleosis mean?

BackgroundLoxoscelism is a severe human envenomation caused by Loxosceles spider venom. To the best of our knowledge, no study has evaluated the presence of antibodies against Loxosceles venom in loxoscelism patients without treatment with antivenom immunotherapy. We perform a comparative analysis for the presence of antibodies capable of recognizing Loxosceles venom in a group of patients diagnosed with loxoscelism and in a group of people without loxoscelism.MethodsThe detection of L. laeta venom, Sicarius venom and recombinant phospholipases D from Loxosceles (PLDs) in sera from people with loxoscelism (Group 1) and from healthy people with no history of loxoscelism (Group 2) was evaluated using immuno-dot blot, indirect ELISA, and Western blot.ResultsWe found naturally heterophilic antibodies (IgG-type) in people without contact with Loxosceles spiders or any clinical history of loxoscelism. Either serum pools or single sera from Group 1 and Group 2 analyzed by dot blot tested positive for L. laeta

Looking for online definition of CD49f antigen in the Medical Dictionary? CD49f antigen explanation free. What is CD49f antigen? Meaning of CD49f antigen medical term. What does CD49f antigen mean?

Chronic active Epstein-Barr virus infection (CAEBV) is characterised by chronic or recurrent infectious mononucleosis-like symptoms, such as fever, hepatosplenomegaly, persistent hepatitis and extensive lymphadenopathy. Patients with CAEBV have high viral loads in their peripheral blood and/or an un …

An adenovirus type-2 was isolated from peripheral blood lymphocytes and throat washings from a patient with severe chronic active Epstein-Barr virus infection. Despite the Epstein-Barr virus reactivation, attempts to establish spontaneous lymphoblastoid cell lines from peripheral blood lymphocytes and to immortalize cord lymphocytes with throat washings were unsuccessful due to a marked cytopathic effect. The supernatants from the cultures induced cytopathic effect in cultured cord lymphocytes, MRC-5 cells, A-549 cells, or Vero cells. Virus particles with adenovirus morphology were seen by electron microscopy. Using type-specific antisera, the isolate was identified as adenovirus type-2. In addition, both Epstein-Barr virus and adenovirus type-2 genomes were seen in the colonic tissues and spleen. These results suggest that the combination of Epstein-Barr virus and adenovirus type-2 may be etiologic agents in the development of chronic active Epstein-Barr virus infection in this patient. ...

Human Anti-Mouse Antibodies (HAMA) may be present in samples from patients who have received immunotherapy utilizing monoclonal antibodies. Additionally, other heterophile antibodies such as human anti-goat antibodies may be present in patient samples. Manufacturers formulate assays to minimize the effects of these antibodies; however careful evaluation of patient results must be done when patients are known to have such antibodies. These specimens should not be assayed with this Digoxin procedure.. Digoxin-Like Immunoreactive Factors (DLIF) or Digoxin-Like Immunoreactive Substances (DLIS) have been identified in blood from patients in renal failure, liver failure, newborns and pregnant women in the third trimester. Studies have established that the presence of DLIF or DLIS in a sample can result in a false elevation of Digoxin by this method.. Specimens from patients undergoing Digoxin Immune FAB (i.e. Digibind) treatment should not be assayed with this Digoxin procedure until 48 hours after ...

TY - JOUR. T1 - Severe chronic active Epstein-Barr virus infection syndrome. AU - Okano, M.. AU - Matsumoto, S.. AU - Osato, T.. AU - Sakiyama, Y.. AU - Thiele, G. M.. AU - Purtilo, D. T.. PY - 1991. Y1 - 1991. N2 - Reports of unusually severe lymphoproliferative disorders associated with extremely high antibody titers against Epstein-Barr virus (EBV) have recently increased. The syndrome, which we designated severe chronic active EBV infection syndrome, is characterized by persistent or intermittent fever, lymphadenopathy, and hepatosplenomegaly and primarily affects children and young adults. Polyclonal gammopathy and bone marrow suppression are generally observed, and some patients develop B-cell or T-cell lymphoproliferation or lymphoma. Frequently, EBV genomes are detectable in tissues infiltrated with lymphoid cells. Additionally, it is difficult to establish spontaneous or B95-8 EBV-induced cell lines despite the expression of an activated EBV infection. We review and report here the ...

The sheep cell agglutination test or heterophile antibody reaction, as it is also called, is a laboratory procedure of considerable value in clinical medicine. In this country one frequently speaks alternately of the Paul-Bunnell test; and in Europe it is often referred to as the Hanganutziu-Deicher reaction. In 1911 Forssman1 recognized the nonspecificity of certain antigen-antibody reactions. The terms "heterogenetic," "heterophilic," or "heterophile" are applied to those antibodies that react with an antigen (sheep erythrocytes) which seemingly had nothing to do with their development. One type of heterophile antibody is known as the Forssman antibody, but there are other varieties ...

PPL THERAPEUTICS PLC. WORLD S FIRST ANNOUNCEMENT OF. CLONED KNOCK-OUT PIGS. Christmas-born pigs are a major step towards successful production of animal organs and cells for human transplantation use. Blacksburg, Virginia: PPL Therapeutics Plc, one of the world s leading biopharmaceutical companies in the application of transgenic technology to the production of human proteins for therapeutic and nutritional applications, is pleased to announce it has produced knock-out piglets which were born as a result of using nuclear transfer (cloning) and PPL s patented gene targeting technology. The five healthy births took place on Christmas Day, December 25, 2001. It has always been the objective of PPL s xenotransplantation program to produce knock-out pigs. In the future, this vital step should enable organs and/or cells from such animals to be transplanted into humans and not be rejected by the human recipient. A knock-out pig has the specific gene that leads to the human immune system rejecting pig ...

g d antigens, b d antigens, n d antigens, j d antigens, u d antigens, y d antigens, h s antigens, h x antigens, h c antigens, h f antigens, h r antigens, h e antigens, h d zntigens, h d sntigens, h d wntigens, h d qntigens, h d abtigens, h d amtigens, h d ajtigens, h d ahtigens, h d anrigens, h d anfigens, h d angigens, h d anyigens, h d an6igens, h d an5igens, h d antugens, h d antjgens, h d antkgens, h d antogens, h d ant9gens, h d ant8gens, h d antifens, h d antivens, h d antibens, h d antihens, h d antiyens, h d antitens, h d antigwns, h d antigsns, h d antigdns, h d antigrns, h d antig4ns, h d antig3ns, h d antigebs, h d antigems, h d antigejs, h d antigehs, h d antigena, h d antigenz, h d antigenx, h d antigend, h d antigene, h d antigenw, gh d antigens, hg d antigens, bh d antigens, hb d antigens, nh d antigens, hn d antigens, jh d antigens, hj d antigens, uh d antigens, hu d antigens, yh d antigens, hy d antigens, h sd antigens, h ds antigens, h xd antigens, h dx antigens, h cd antigens, ...

TY - JOUR. T1 - Interaction of antibody with Forssman antigen in guinea pigs. T2 - A mechanism of adaptation to antibody- and complement-mediated injury. AU - Yuzawa, Y.. AU - Brett, J.. AU - Fukatsu, A.. AU - Matsuo, S.. AU - Caldwell, P. R.B.. AU - Niesen, N.. AU - Milgrom, F.. AU - Godman, G.. AU - Stern, D.. AU - Andres, G.. PY - 1995. Y1 - 1995. N2 - Forssman antigen is a glycosphingolipid with antigenic specificity determined by extra-membrane haptenic sugars similar to blood group antigens and antigens that are the main barrier to xenogeneic organ transplantation. Herein, we describe the localization of Forssman antigen in guinea pig lungs and kidneys and the consequences of its interaction with antibodies in vitro and in vivo (Forssman reaction). Exposure of cultured guinea pig aortic endothelial cells to Forssman antibodies induced rapid redistribution of antigen-antibody complexes at the cell surface, followed by shedding that occurred by blebbing of plasma membrane as vesicles or ...

TY - JOUR. T1 - Platelets and Factor VIII in von Willebrand's Disease. AU - Green, D.. AU - Potter, E. V.. PY - 1977/6/9. Y1 - 1977/6/9. N2 - To the Editor: In his excellent review, Jaffe1 asks, "What happens to the factor VIII antigen content of the two platelet pools when patients with von Willebrand's disease of severe degree are given transfusions of plasma factor VIII?" We have performed in vitro and in vivo studies to answer his question. Immunofluorescent staining of platelets of patients with von Willebrand's disease incubated with normal plasma indicated that factor VIII antigen did not become platelet bound unless aggregation was induced by ristocetin.2 Likewise, platelets obtained from such patients after cryoprecipitate infusion showed minimal or no staining before but intense staining. No extract is available for articles shorter than 400 words.. AB - To the Editor: In his excellent review, Jaffe1 asks, "What happens to the factor VIII antigen content of the two platelet pools when ...

TY - JOUR. T1 - Successful liver transplantation (OLT) in a child with fulminant hepatic failure due to primary ebv infection. T2 - 154. AU - Feranchak, A. P.. AU - Karrer, F. M.. AU - Narkewicz, M. R.. AU - Tyson, R. W.. AU - Sokol, R. J.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 1997/10. Y1 - 1997/10. UR - http://www.scopus.com/inward/record.url?scp=85026166755&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85026166755&partnerID=8YFLogxK. U2 - 10.1097/00005176-199710000-00171. DO - 10.1097/00005176-199710000-00171. M3 - Article. AN - SCOPUS:85026166755. VL - 25. SP - 480. JO - Journal of Pediatric Gastroenterology and Nutrition. JF - Journal of Pediatric Gastroenterology and Nutrition. SN - 0277-2116. IS - 4. ER - ...

A 16-year-old boy had IIB von Willebrand's disease. The disorder is characterized by prolonged bleeding times; normal plasma levels of factor VIII-coagulant activity, factor VIII-ristocetin cofactor activity, and factor VIII-related antigen; abnormal (anodal) mobility of plasma factor VIII-related antigen on two-dimensional crossed Immunoelectrophoresis; and enhanced binding of plasma factor VIII-related antigen to normal platelets in the presence of ristocetin. These variables were measured at time periods after an infusion of normal cryoprecipitate into the patient. The electrophoretic mobility of his plasma factor VIII-related antigen was normal 15 minutes after the infusion but became abnormal (anodal) by 4 hours. His bleeding times were normal after 24 hours and did not correlate with plasma levels of factor VIII-coagulant activity, factor VIII-ristocetin cofactor, factor VIII-related antigen, or the electrophoretic mobility of his plasma factor VIII-related antigen. These results imply ...

The Kidd antigen system (also known as Jk antigen) is present on the membranes of red blood cells and the kidney and helps determine a person's blood type. The Jk antigen is found on a protein responsible for urea transport in the red blood cells and the kidney. The gene encoding this protein is found on chromosome 18. Three Jk alleles are Jk (a), Jk (b)and Jk3. Jk (a) was discovered by Allen et al. in 1951 and is named after a patient (Mrs Kidd delivered a baby with a haemolytic disease of the newborn associated with an antibody directed against a new antigen Jk (a). Whereas Jk (b) was discovered by Plant et al. in 1953, individuals who lack the Jk antigen (Jk null) are unable to maximally concentrate their urine. The Jk antigen is important in transfusion medicine. People with two Jk(a) antigens, for instance, may form antibodies against donated blood containing two Jk(b) antigens (and thus no Jk(a) antigens). This can lead to hemolytic anemia, in which the body destroys the transfused blood, ...

in Acta Clinica Belgica (2013), 68(6), 465. Introduction: Beyond pregnancy, persistent low levels of hCG may be associated with various benign and malignant conditions, i.e. quiescent gestational trophoblastic disease (QTD), raised pituitary hCG or ... [more ▼]. Introduction: Beyond pregnancy, persistent low levels of hCG may be associated with various benign and malignant conditions, i.e. quiescent gestational trophoblastic disease (QTD), raised pituitary hCG or false positive elevation caused by circulating heterophilic antibodies. This situation requires a clinico-biological approach in order to avoid misunderstandings that could lead to inappropriate diagnostic or therapeutic attitudes. Observation: A 23 years old woman (GOPO status) consulted his gynaecologist because of persistent abdominal pain. She was diagnosed of having trophoblastic disease on the basis of persistently positive human chorionic gonadotropin (hCG) test (Roche Modular) results, in the absence of pregnancy. Persistent ...

Porcine circovirus type 2 Capsid antibody for IHC, IHC-P, WB. Anti-Porcine circovirus type 2 Capsid pAb (GTX128120) is tested in Porcine circovirus type 2 samples. 100% Ab-Assurance.

To the Editor: Misra and colleagues (1) reported an increased incidence of anticardiolipin antibodies in patients with infectious mononucleosis and postulated the existence of cross-reactions between infectious (viral) antigens and cardiolipin. We report here our experience concerning immunologic and biochemical similarities between Pneumocystis carinii organisms and cardiolipin. We observed that in the acquired immunodeficiency syndrome (AIDS), anticardiolipin antibodies occurred almost exclusively among those patients who had active P. carinii pneumonia (2). To test the cross-reactive hypothesis, we did several experiments.. In the first set of experiments, rabbits were immunized with an antigen from P. carinii in Freund's adjuvant prepared according ...

Detailed information on adolescent health problems and injuries, including acne, asthma, breast conditions, breast self-examination, diabetes, eye care, eye safety, gynecological conditions, menstrual conditions, gynecologic problems, pap test, vaginitis, vulvitis, menstrual disorders, amenorrhea, dysmenorrhea, premenstrual syndrome (PMS), high blood pressure, infectious mononucleosis, obesity, oral health, orthodontics, braces, wisdom teeth extraction, periodontal disease, orthopedic problems, osgood schlatter disease, scoliosis, slipped capital femoral epiphysis, sexually transmitted diseases, safer sex guidelines, sports safety, sports injuries, sprains, strains, tennis elbow, mouthguards, heat related illness, heat cramps, heat exhaustion, and heat stroke

Fingerprint Dive into the research topics of 'Linkage assignment of the last unmapped cattle erythrocyte antigen system, EAF'. Together they form a unique fingerprint. ...

The Yt antigen system (also known as Cartwright) is present on the membrane of red blood cells and helps determine a person's blood type. The antigens are found on the protein acetylcholinesterase, an enzyme which helps break down acetylcholine. The Yt system features two alleles, Yt(a) and Yt(b). Antibodies against the Yt system can lead to transfusion reactions such as hemolytic anemia. Online Mendelian Inheritance in Man (OMIM) 112100 - OMIM page on Yt antigen Bartels, CF; Zelinski, T; Lockridge, O (1993). "Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism". American Journal of Human Genetics. 52 (5): 928-36. PMC 1682033 . PMID 8488842. Yt at BGMUT Blood Group Antigen Gene Mutation Database at NCBI, ...

Looking for online definition of antibody-antigen complex in the Medical Dictionary? antibody-antigen complex explanation free. What is antibody-antigen complex? Meaning of antibody-antigen complex medical term. What does antibody-antigen complex mean?

J Swaminathan, C Ehrhardt, Effect of lyophilisation on liposomal systems for the delivery of salmon calcitonin (sCT), J Liposome Res, 24, 4, 2014, 297-303 ...

Fingerprint Dive into the research topics of 'GPI-anchored glycoconjugates from ,em,Trypanosoma cruzi,/em, trypomastigotes are recognized by lytic anti-alpha-galactosyl antibodies isolated from patients with chronic Chagas' disease'. Together they form a unique fingerprint. ...

It has been generally accepted for more than half a century that, in most mammalian species, oocytes cannot renew themselves in postnatal or adult life, and that the number of oocytes is already fixed in fetal or neonatal ovaries. This assumption, however, has been challenged over the past decade. In this study, we have taken an endogenous genetic approach to this question and generated a multiple fluorescent Rosa26rbw/+;Ddx4-Cre germline reporter mouse model for in vivo and in vitro tracing of the development of female germline cell lineage. Through live cell imaging and de novo folliculogenesis experiments, we show that the Ddx4-expressing cells from postnatal mouse ovaries did not enter mitosis, nor did they contribute to oocytes during de novo folliculogenesis. Our results provide evidence that supports the traditional view that no postnatal follicular renewal occurs in mammals, and no mitotically active Ddx4-expressing female germline progenitors exist in postnatal mouse ovaries. ...

2] The reason for decreased mortality in the HIV-infected population was determined to be low intensity of inflammation and effective surgical cerebrospinal fluid drainage for increased intracranial pressure.. Cytomegaloviral infection usually presents as ventriculoencephalitis, with possible meningeal involvement, while aseptic HIV-associated meningitis appears as a mononucleosis-like illness and in rare cases is associated with encephalitis.. The differential diagnosis of HIV-associated meningitis includes chronic paroxysmal hemicrania, meningococcal meningitis, migraine headache, neurosyphilis, and staphylococcal meningitis. Other problems to be considered include lymphomatous meningitis; bacterial meningitis, which often occurs in conjunction with sepsis; and cytomegalovirus ventriculoencephalitis, which usually results in a change in mental status that evolves over several weeks and can be misdiagnosed as HIV-associated dementia.. In patients receiving highly active antiretroviral therapy ...

Semantic Scholar extracted view of 'Immune responsiveness to Mycobacterium leprae of healthy humans. Application of the leucocyte migration inhibition test.' by Bjørn Myrvang

PRIMARY OBJECTIVES:. I. To define the maximum tolerated dose (MTD) of Combotox (deglycosylated ricin A chain-conjugated anti-CD19/anti-CD22 immunotoxins) when added to high-dose cytarabine during salvage therapy for adult patients with relapsed or refractory B-lineage acute lymphoblastic leukemia.. SECONDARY OBJECTIVES:. I. To evaluate the efficacy of this regimen. II. To assess for the presence of a postulated CD34+/CD38-/low/CD19+ leukemic stem cell phenotype in the bone marrow at time of relapse and to assess its association with treatment outcome.. III. To determine the development of human mouse or ricin antibodies (human anti-mouse antibodies [HAMA]/human anti-ricin antibodies [HARA]).. IV. To determine the pharmacokinetic characteristics of Combotox. V. To evaluate the value of fractional excretion of sodium (FeNa) as early marker of toxicity.. OUTLINE: This is a dose-escalation study of deglycosylated ricin A chain-conjugated anti-CD19/anti-CD22 immunotoxins.. Patients receive high-dose ...

Epstein-Barr virus (EBV) associated lymphoproliferative disorder (LPD) after immunosuppressive therapy for aplastic anemia (AA) is extremely rare in a nontransplant setting and has not been well described. This report describes a severe AA patient in whom fatal EBV-LPD developed after being treated with rabbit antithymocyte globulins (ATG) and cyclosporine A (CsA). An 81-year-old man was diagnosed as having severe AA. He was started on CsA followed by administration of ATG for five consecutive days. One month after the start of ATG, persistent fever which was not responsive to antibiotics or antifungal agents developed and atypical lymphocytes emerged in peripheral blood. Repeated blood cultures were negative. An extremely high level of EBV virus in his peripheral blood plasma was detected by means of a quantitative real-time PCR assay. Even after the cessation of CsA, the fever persisted and the peripheral atypical lymphocytes proliferated rapidly. The patient suffered from respiratory failure, liver

Sialic acids are prominent termini of mammalian glycoconjugates and are key binding determinants for cell-cell recog-nition lectins. Binding of the sialic acid-dependent lectin, myelin-associated glycoprotein (MAG), to nerve cells is implicated in the inhibition of nerve regeneration after injury. Therefore, blocking MAG binding to nerve cell sialoglycoconjugates might enhance nerve regeneration. Previously, we reported that certain sialoglycoconjugates bearing N-acetylneuraminic acid (NeuAc) but not N-glycolylneuraminic acid (NeuGc) support MAG binding (Collins et al., 1997a). We now report highly efficient conversion of sialic acids on living neural cells from exclusively NeuAc to predominantly NeuGc using a novel synthetic metabolic precursor, N-glycolylmannosamine pentaacetate (Man-NGc-PA). When NG108-15 neuroblastoma-glioma hybrid cells, which normally express only NeuAc (and bind to MAG), were cultured in the presence of 1 mM ManNGcPA, they expressed 80-90% of their sialic acid precursor pool as

Protective antigen component of B. anthracis toxin was produced and purified to the |99% level. Toxin was purified from culture supernatant utilizing concentration and liquid chromatography techniques. Purity was determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The purified protective antigen retained biological and antigenic activity as evidenced respectively by lethality in Fischer 344 rats when injected in combination with lethal factor, and by positive results on the Ouchterlony double diffussion assay. Radioiodinated protective antigen was used both in the in vivo and the in vitro experiments. In vivo distribution of labelled protective antigen was determined in Fischer 344 rats. Assay of organ tissues for labelled protective antigen aided in the decision to use Maden-Darby bovine kidney cells for the cell cultures in the protective antigen binding studies. Protective antigen binding studies, all performed at 37°C, evaluated criteria for receptor existence. Labelled

TY - JOUR. T1 - A technique for isolating heterophils from blood of orange-winged Amazon parrots (Amazona amazonica amazonica). AU - Tell, Lisa A. AU - Kabbur, M. B.. AU - Smith, W. L.. AU - Dahl, K. H.. AU - Cullor, James S. PY - 1997. Y1 - 1997. N2 - Blood samples from adult orange-winged Amazon parrots (Amazona amazonica amazonica) were collected to develop a rapid and efficient technique for isolating pure populations of morphologically intact and functional heterophils. In addition, normal haematological parameters for the orange-winged Amazon parrots (n = 20) were established and found to be within the reported range of other Amazon species. Heterophil isolation (n = 16) was maximally achieved by concentrating the white blood cells with 3% hetastarch prior to running the sample through a polysucrose and disodium diatrizoate centrifugation. The isolation procedure yielded an average heterophil recovery of 61.9%, the purity exceeded 92.6% and viability was 98.9%. Cell integrity was evaluated ...

TY - JOUR. T1 - Cyclosporine concentrations in blood after liver transplantation. T2 - Correlation of immunoassay results with clinical events. AU - Haven, M. C.. AU - Sobeski, L. M.. AU - Earl, R. A.. AU - Markin, R. S.. PY - 1989. Y1 - 1989. N2 - To investigate the clinical utility of immunoassays for cyclosporine and metabolites in plasma and whole blood, we monitored 25 patients after orthotopic liver transplantation. We compared cyclosporine as measured by TDx fluorescence polarization immunoassay (of both plasma and whole blood) and by two polyclonal radioimmunoassays (from Sandoz and INCSTAR). We found considerable differences in measured cyclosporine concentrations, which were dependent on method, matrix, and clinical condition. Correlation coefficients between results by the various methods for samples from individual patients ranged from 0.825 to 0.996. The three methods used for monitoring cyclosporine in whole blood gave proportional results (Sandoz , INCSTAR , TDx) in individual ...

LONDON, Dec. 28, 2012 /PRNewswire/ - Bio-AMD, Inc. is pleased to announce that Bio AMD Limited, our majority owned medical devices subsidiary ("Bio-AMD", "We" or the "Company") (OTCBB: BIAD.OB), (OTCQB: BIAD) has submitted a UK Intellectual Property Office patent application for an Immunoassay Result Reading Apparatus ("IRRA").. The IRRA has been developed alongside the work on our Digital Strip Reader ("DSR") technology platform. The Company is in commercialisation discussions regarding DSR which digitises and semi-quantifies the results of existing lateral flow tests, significantly enhancing diagnostic capability for the end user.. The Company believes that the IRRA technology can be applied to any current analogue lateral flow test strip. These types of tests are generally characterised by the appearance of a coloured line when the test is positive. However, where the substance of interest is present in relatively low concentrations (for example in the early days of pregnancy) the coloured ...

In most cases of infectious mononucleosis, the clinical diagnosis can be made from the characteristic triad of fever, pharyngitis, and lymphadenopathy lasting for 1 to 4 weeks. Serologic test results include a normal to moderately elevated white blood cell count, an increased total number of lymphocytes, greater than 10% atypical lymphocytes, and a positive reaction to a "mono spot" test. In patients with symptoms compatible with infectious mononucleosis, a positive Paul-Bunnell heterophile antibody test result is diagnostic, and no further testing is necessary. Moderate-to-high levels of heterophile antibodies are seen during the first month of illness and decrease rapidly after week 4. False-positive results may be found in a small number of patients, and false-negative results may be obtained in 10% to 15% of patients, primarily in children younger than 10 years of age. True outbreaks of infectious mononucleosis are extremely rare. A substantial number of pseudo-outbreaks have been linked to ...

Fingerprint Dive into the research topics of 'Erratum: Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection (Xenotransplantation (2011) DOI: 10.1111/j.1399-3089.2011.00633.x)'. Together they form a unique fingerprint. ...

The conformational preorganization and anion-induced conformational changes of indole-based receptors functionalized with an amide group at the 2-position and a variety of amide, urea and thiourea moieties at the 7-position have been studied by the means of NMR spectroscopy. NOE experiments showed that anti-anti orientation across C2-C2 and C7-N7 bonds is preferred for receptors 1-4 in acetone solution in the absence of anions. Anion-receptor interactions have been evaluated through 1H and 15N chemical shift changes. In 2,7-bis-carboxamido functionalized indoles the interaction with chloride and bromide anions primarily occurs at the indole H1 proton. The introduction of urea and thiourea moieties increases the number of hydrogen bond donor sites which manifests itself in a distribution of halide-receptor interactions among the H1, H7 and H7 protons. Acetate anions also interact strongly with indole and urea NH donor groups, whereas nitrate anions interact solely with H7 and H7 urea/thiourea ...

TY - JOUR. T1 - Accurate sampling of high-frequency motions in proteins by steady-state 15N-{ 1H} nuclear overhauser effect measurements in the presence of cross-correlated relaxation. AU - Ferrage, Fabien. AU - Cowburn, David. AU - Ghose, Ranajeet. N1 - Copyright: Copyright 2012 Elsevier B.V., All rights reserved.. PY - 2009/5/6. Y1 - 2009/5/6. N2 - The steady-state { 1H}- 15N NOE experiment is used in most common NMR analyses of backbone dynamics to accurately ascertain the effects of the fast dynamic modes. We demonstrate here that, in its most common implementation, this experiment generates an incorrect steady state in the presence of CSA/dipole cross-correlated relaxation leading to large errors in the characterization of these high-frequency modes. This affects both the quantitative and qualitative interpretation of 15N backbone relaxation in dynamic terms. We demonstrate further that minor changes in the experimental implementation effectively remove these errors and allow a more ...

Tumour stromal macrophages differentiate to tumour-associated macrophages (TAMs) with characteristics of immunosuppressive M2-type macrophages, having a central role in promoting tumour vascularisation, cancer cell dissemination and in suppressing anti-cancer immune responses. Bisphosphonates (BPs) are a group of drugs commonly used as anti-resorptive agents. Further, nitrogen containing BPs like Zoledronate (ZOL), are known to cause unspecific inflammatory reactions hence the hypothesis that its use could modulate TAMs polarization toward a more inflammatory phenotype. We studied the in vitro polarization of J774 murine macrophages upon culture in 4T1 breast cancer cell-conditioned medium (4T1CM) and stimulation with LPS and free and liposome-encapsulated bisphosphonates. In this system, breast cancer soluble factors reduced the pro-inflammatory activation of macrophages but increased the secretion of matrix metalloproteinases (MMPs). In the presence of 4T1CM, a non-cytotoxic dose of liposome

Synonyms for Antibodies, heterophile in Free Thesaurus. Antonyms for Antibodies, heterophile. 4 synonyms for infectious mononucleosis: glandular fever, kissing disease, mono, mononucleosis. What are synonyms for Antibodies, heterophile?

It is known that various DHP calcium antagonists enhance the NO release from endothelial cells.14 15 16 17 18 19 Using an NO-sensitive electrode, we previously demonstrated that nifedipine in the micromolar and submicromolar concentration ranges stimulates the NO release from the native endothelium.33 34 These findings were obtained after acute exposure to DHP calcium antagonists. Therefore, we investigated whether (1) a long-term treatment (48 hours, entire passage 2) of porcine endothelial cell cultures with nifedipine resulted in a similarly altered NO release and (2) an increased formation and/or an impaired inactivation of NO might be involved by measuring the ecNOS (NOS isoform III) mRNA and protein expression and the antioxidative potency of nifedipine, respectively.. In contrast to the short-term measurements during long-term treatment, nifedipine was not present in the buffer during the antioxidative and NO experiments.. We could demonstrate that treatment with nifedipine (concentration ...

100% money-back guarantee: if our liposomal c do not bring noticeable value to you and you don't absolutely love them, we will refund your money; Our world-class customer service wants you to be SATISFIED with your purchase; Absolutely no risk; The bottle comes with our 100% satisfaction guarantee for 60 days; Have this all-mighty antioxidant supplement and health protector by your side and defend against flu and common colds, everyday. Groundbreaking 1400mg, from our 1400 mg per serving of vitamin c, plus more benefits, quality-guaranteed liposomal vit c: industry leading 1400 milligrams liposomal vitamin c complex based on liposomal technology; Each bottle contains 180 Vegetable Capsules Plant-derived for a full 3 months supply; Don't settle for 500mg or 1000mg Liposomal C supplements - Experience amazing Immune and Nervous system support, a boost in Collagen Production, without breaking the bank ...

Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map. ...

Preparations useful in the diagnosis of infectious mononucleosis are disclosed. Horse and sheep erythrocytes are purified and essentially homogenous glycoproteins are extracted. The purified glycoproteins are useful as antigens in testing for the presence of the heterophile antibodies of infectious mononucleosis and in the preparation of reagents for the enumeration of rosetting lymphocytes without having to have available fresh sheep blood.

J:188842 Bergfeld AK, et al., Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem. 2012 Aug 17;287(34):28865-81 ...

The QuickVue+ Mononucleosis Test detects IgM heterophile antibodies in acute phase infections using serum, plasma or whole blood.

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