Sex differences in peripheral immune responses are well recognized. This is associated with sex differences in many immunological diseases. As the intestinal microbiota is known to influence the immune system, such sex differences in immune responses may be a consequence of sex-specific microbiota. Therefore, this mini-review discusses sex differences in intestinal microbiota and the possible role of microbiota in shaping sexually dimorphic immunity. Sex differences in microbiota composition are clearly found in mice studies and also in human studies. However, the lack of standardization in human studies may mask the sexual dimorphism in microbiota composition in human studies, since many factors such as age, genetic background, BMI, diet, and sex hormones appear to interfere with the sexual dimorphism in microbiota composition. Only a few mice studies found that differences in gut microbiota composition are causative for some aspects of sexually dimorphic immunity. Therefore, future studies should
Beyond its role in therapy, FMT is providing insights into the importance of intestinal microbiota in health and disease. As physicians and scientists, we live in exciting times! Bacteria are no longer viewed solely as pathogens, but also as key partners in the maintenance of health. It is conceivable that altering the microbiota in our gastrointestinal tract may either predispose us to disease or ameliorate conditions we already have. Faecal microbiota transplantation (FMT) has captured the attention of the lay press and professional journals since 1958, when faecal enema was reported to have cured four patients near death from severe Micrococcus pyogenes colitis.1. ...
Public awareness about the importance of the gut microbiota is growing, but many nutrition professionals struggle to know how to incorporate findings from gut microbiota science into their practice. In a rapidly-progressing field, what should clinicians know about how gut microbes and diet interact to produce different health outcomes?. At the 2017 Gut Microbiota for Health World Summit in Paris on March 11th and 12th, Dr. Elena Verdú, Associate Professor at McMaster University (Canada) chaired a special workshop for registered dietitians and physicians specializing in nutrition and gastrointestinal disorders. The workshop -called "Nutrition and the human gut microbiome: What should health professionals know for their daily practice?"- addressed issues and questions relevant to nutrition practice.. The official report of this clinically-oriented session is now available! See below or download it at this link.. The full conference report from the GMFH World Summit 2017 is available here.. GMFH ...
The gut microbiota has the capability to generate a series of metabolites and thereby regulate homeostasis of the host metabolism (1). Antibiotic treatment, as an important therapeutic approach in clinical practice, can adversely affect the gut microbiota, inevitably giving rise to metabolic disorders (19). However, whether antibiotics have sex-dependent effects on the gut microbiota and host metabolism is unknown.. In the present study, at first we found that the gut microbiome and metabolome are influenced by gender. Results showed that male mice had higher abundances of Adlercreutzia, AF12, Anaeroplasma, Bacteroides, Dehalobacterium, Dorea, Mucispirillum, Roseburia, and Ruminococcus as well as lower levels of Lactobacillus, Prevotella, and Sutterella than female mice. In fact, sex-dependent differences in the gut microbiota have been reported due to hormonal effects (20), but many other factors may also affect microbial composition changes, such as genotype (21), age (22), body weight (23), ...
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric condition that may be related to an imbalance of neural transmitters. The gut microbiota is the largest ecosystem in the human body, and the brain-gut axis theory proposes that the gut microbiome can affect brain function in multiple ways. The purpose of this study was to explore the gut microbiota in children with ADHD and assess the possible role of the gut microbiota in disease pathogenesis to open new avenues for ADHD treatment.MethodsA case-control design was used. We enrolled 17 children aged 6-12 years with ADHD who were treated in the Pediatric Outpatient Department of the First Medical Center of the Chinese PLA General Hospital from January to June, 2019. Seventeen children aged 6-12 years were selected as the healthy control (HC) group. Fecal samples of cases and controls were analyzed by shotgun metagenomics sequencing. Alpha diversity and the differences in the relative abundances of bacteria were compared
Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). Lupus patients who experienced pregnancy usually had more severe disease flares post-delivery. However, the possible role of gut microbiota in the link between pregnancy and exacerbation of lupus remains to be explored. In the classical lupus mouse model MRL/lpr, we compared the structures of gut microbiota in pregnant and lactating individuals vs. age-matched naïve mice. Consistent with studies on non-lupus mice, both pregnancy and lactation significantly changed the composition and diversity of gut microbiota. Strikingly, modulation of gut microbiota using the same strategy resulted in different disease outcomes in postpartum (abbreviated as
The role of gut microbiota has been extensively researched in recent years and it has been demonstrated that healthy gut microbiota can stimulate proper development of the immune system, provide humans with extra energy and protect against invading pathogens.. However, gut dysbiosis - an imbalance of the resident gut microbiota population instigated by a long-term high-fat and high-sugar diet - results in an increased inflammatory tone both locally and systematically which is a factor to bone loss.. The reports authors looked at all relevant, published, up-to-date findings on the subject of obesity, gut microbiota and jaw bone density, in order to establish a relationship between the three.. They found that the recent data did suggest that diet-induced obesity has a negative impact on bone health possibly via the alteration of gut microbiota and host immune status, and that manipulating gut microbiota could improve bone health.. The majority of the studies looked at were animal studies, largely ...
The gut microbiota is a complex ecosystem that wields great influence over the health of its host.32 Conversely, mammalian hosts use a broad array of mechanisms to shape the microbiota in a way that maximises its benefit and minimises its potential to harm.33 That, at least among healthy persons, intraindividual variance in microbiota composition (ie, repeat sampling of individual subjects) is much smaller than that seen when comparing different individuals33-35 indicates that the ability of host and microbiota to influence each other typically results in a relatively stable equilibrium within specific hosts. Yet, some exogenous factors, for example, pathogens or antibiotics, can dramatically and lastingly disturb this equilibrium in a manner that promotes persistent disease.36 Moreover, even factors that cause relatively modest disturbances of the host-microbiota relationship have been associated with chronic low-grade inflammatory diseases, including metabolic syndrome.36 The genetics of the ...
The handling and treatment of biological samples is critical when characterizing the composition of the intestinal microbiota between different ecological niches or diseases. Specifically, exposure of fecal samples to room temperature or long term storage in deep freezing conditions may alter the composition of the microbiota. Thus, we stored fecal samples at room temperature and monitored the stability of the microbiota over twenty four hours. We also investigated the stability of the microbiota in fecal samples during a six month storage period at −80°C. As the stability of the fecal microbiota may be affected by intestinal disease, we analyzed two healthy controls and two patients with irritable bowel syndrome (IBS). We used high-throughput pyrosequencing of the 16S rRNA gene to characterize the microbiota in fecal samples stored at room temperature or −80°C at six and seven time points, respectively. The composition of microbial communities in IBS patients and healthy controls were determined
Background: Although immune responses directed against antigens from the intestinal microbiota are observed in certain diseases, the normal human adaptive immune response to intestinal microbiota is poorly defined. Objective: Our goal was to assess the adaptive immune response to the intestinal microbiota present in 143 healthy adults and compare this response with the response observed in 52 children and their mothers at risk of having allergic disease. Methods: Human serum was collected from adults and children followed from birth to 7 years of age, and the serum IgG response to a panel of intestinal microbiota antigens was assessed by using a novel protein microarray. Results: Nearly every subject tested, regardless of health status, had serum IgG that recognized a common set of antigens. Seroreactivity to the panel of antigens was significantly lower in atopic adults. Healthy infants expressed the highest level of IgG seroreactivity to intestinal microbiota antigens. This adaptive response ...
We read with interest the paper by Rehman et al1 reporting the contribution of Nod2 genotype to the composition of gut microbiota in mice and Crohns disease (CD) patients. This was followed by a similar description for another CD-predisposing gene, FUT2.2 To date, 163 CD- and ulcerative colitis-risk loci have been identified, and while most of the known causative genes are involved in immune functions and response to infections, their effects on the composition of the gut microbiota are mostly unknown. Studies like those mentioned above are therefore very important, since the relative abundance of specific enteric bacteria has been clearly shown to be of pathogenetic relevance in mouse models of colitis.3 By studying genotype-microbiota correlations in healthy individuals, key information could also be sought for devoid of potentially confounding effects from disease status and therapeutic treatment.. We studied the impact of 30 unequivocal CD-risk loci, each tagged by a single nucleotide ...
This study constitutes the largest and deepest sampling of the composition of the elderly gut microbiota reported to date. The fecal microbiota of younger adults was previously shown by temperature gradient gel electrophoresis (TGGE) and phylochip (HitChip) analysis to be stable and individual-specific (7, 42). In the present study, all 161 of the time-0 microbiota samples could be clearly separated by UniFrac analysis (Fig. S5), and fine-detail analysis of genus confirmed individual-specific microbiota configurations. The HitChip study also found that temporally paired samples from elderly subjects were more similar than randomly compared samples from different subjects. However, the similarity of paired samples decreased from time 1 mo to time 2 mo. In the five elderly subjects that they investigated, the decrease in microbiota similarity was more pronounced in the Actinobacteria (42), whereas in younger adults, greatest divergence was recorded for Clostridium cluster IV. We observed a similar ...
The Human Intestinal Microbiota Has A Great Diversity Of Microorganisms, Playing An Important Role In Metabolism. Despite The Positive Aspects, The Intestinal Microbiota Is Associated With The Development Of Various Diseases Such As Inflammatory Bowel Disease, Celiac Disease, Allergic Diseases, And Diabetes. Type 1 Diabetes Mellitus (T1d) Is A Chronic Autoimmune Disease Characterized By Increased Blood Glucose Levels Due To A Deficiency In Insulin Production As A Result Of Pancreatic "-Cell Destruction. The Pathophysiology Of Dm1 Is Still Not Fully Understood, However, Only Genetic Factors Are Not Sufficient To Determine The Risk Of Developing The Disease. The Role Of The Intestinal Microbiota As One Of The Triggers Of T1d Has Been Evaluated In Animal And Human Studies, And Strong Evidence Is Available For A Microbiota That Promotes Disease Development. This Study Aims To Compare Fecal Microbiota Among Children And Adolescents With T1d, Their Siblings And Healthy Children With No Family ...
Interestingly, there was a significant drop in interindividual beta-diversity in a short period of time after birth (3-10 days), as assessed by mixed sequencing. Due to practical reasons, many temporal research studies of faecal microbiota face a trade-off between sampling frequency and number of individuals included in the study. To our knowledge, all temporal faecal microbiota studies to date that have extensive sampling during first weeks of life (Favier et al., 2003; Palmer et al., 2007; Koenig et al., 2011) have few individuals analysed, whereas studies with high sample numbers often have fewer or more infrequent time points (Yatsunenko et al., 2012). However, our results illustrate that significant differences in average bacterial composition and beta-diversity occur between 3 and 10 days of age. These data therefore suggest that to better understand the development of gut microbiota, gaps between sampling periods should be reduced, particularly for those studies that compare different ...
We show here the importance of NOD2 in driving a proinflammatory immune response by myeloid cells, inducing the differentiation of pathogenic Th1 and Th17 cells, thus resulting in pancreatic insulitis and the consequent destruction of insulin-producing pancreatic β cells and STZ-induced T1D development. Mice lacking NOD2, but not NOD1, did not develop STZ-induced T1D and were unable to induce a Th1 and Th17 immune response in the PLNs and pancreas. Furthermore, diabetic mice had changes in the composition of the gut microbiota, which may be related to the observed bacterial translocation to the PLNs. Notably, antibiotic treatment impaired both the bacterial translocation to the PLNs and the changes in the gut microbiota, which was correlated with protection from the disease. Additionally, we show here that NOD2 plays a critical role in gut microbiota recognition because the addition of the NOD2 ligand, MDP, was sufficient to promote STZ-induced T1D in Abx-treated, STZ-injected WT mice. ...
Recent data suggest that the gut microbiota plays a significant role in fat accumulation. However, it is not clear whether gut microbiota is involved in the pathophysiology of type 2 diabetes. To assess this issue, we modulated gut microbiota via antibiotics administration in two different mouse models with insulin resistance. Results from dose-determination studies showed that a combination of norfloxacin and ampicillin, at a dose of 1 g/L, maximally suppressed the numbers of cecal aerobic and anaerobic bacteria in ob/ob mice. After a 2-wk intervention with the antibiotic combination, both ob/ob and diet-induced obese and insulin-resistant mice showed a significant improvement in fasting glycemia and oral glucose tolerance. The improved glycemic control was independent of food intake or adiposity because pair-fed ob/ob mice were as glucose intolerant as the control ob/ob mice. Reduced liver triglycerides and increased liver glycogen correlated with improved glucose tolerance in the treated mice.
TY - JOUR. T1 - Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation. AU - Fujimura, Kei E.. AU - Sitarik, Alexandra R.. AU - Havstad, Suzanne. AU - Lin, Din L.. AU - Levan, Sophia. AU - Fadrosh, Douglas. AU - Panzer, Ariane R.. AU - Lamere, Brandon. AU - Rackaityte, Elze. AU - Lukacs, Nicholas W.. AU - Wegienka, Ganesa. AU - Boushey, Homer A.. AU - Ownby, Dennis Randall. AU - Zoratti, Edward M.. AU - Levin, Albert M.. AU - Johnson, Christine C.. AU - Lynch, Susan V.. PY - 2016/10/1. Y1 - 2016/10/1. N2 - Gut microbiota bacterial depletions and altered metabolic activity at 3 months are implicated in childhood atopy and asthma. We hypothesized that compositionally distinct human neonatal gut microbiota (NGM) exist, and are differentially related to relative risk (RR) of childhood atopy and asthma. Using stool samples (n = 298; aged 1-11 months) from a US birth cohort and 16S rRNA sequencing, neonates (median age, 35 d) were divisible into three ...
Our study focused on comparing the microbiota of patients diagnosed with adenoma, advanced adenoma, and carcinoma before and after treatment. For all three groups of patients, we observed changes in their microbiota. Some of these changes, specifically for adenoma, may be due to normal temporal variation, however, those with advanced adenoma and carcinoma clearly had large microbiota changes. After treatment, the microbiota of patients with carcinoma changed significantly more than the other groups. This change resulted in communities that more closely resembled those of patients with a normal colon. This may suggest that treatment for carcinoma is not only successful for removing the carcinoma but also at reducing the associated bacterial communities. Understanding the effect of treatment on the microbiota of those diagnosed with carcinomas may have important implications for reducing disease recurrence. It is intriguing that it may be possible to use microbiome-based biomarkers to not only ...
Gut Microbiota and Health - Sneaking through barrier gaps: Gut microbiota imbalance harms the liver | HealthPRZone.com - Making PR Easy for Healthcare Professionals
The intestinal tract is inhabited by a large and diverse community of microbes collectively referred to as the gut microbiota. While the gut microbiota provides important benefits to its host, especially in metabolism and immune development, disturbance of the microbiota-host relationship is associated with numerous chronic inflammatory diseases, including inflammatory bowel disease and the group of obesity-associated diseases collectively referred to as metabolic syndrome. A primary means by which the intestine is protected from its microbiota is via multi-layered mucus structures that cover the intestinal surface, thereby allowing the vast majority of gut bacteria to be kept at a safe distance from epithelial cells that line the intestine. Thus, agents that disrupt mucus-bacterial interactions might have the potential to promote diseases associated with gut inflammation. Consequently, it has been hypothesized that emulsifiers, detergent-like molecules that are a ubiquitous component of ...
A recently published study in Science from researchers at the University of Texas Southwestern (UT; TX, USA) has demonstrated that NFIL3 is expressed in small IECs. They also discovered that the gut microbiome appears to regulate lipid uptake and storage by altering the function of the circadian clock in these cells.. Lora Hooper (UT), the lead author of the study, commented: "These findings indicate a mechanism by which the intestinal microbiota regulate body composition and establish the circadian transcription factor NFIL3 as the essential molecular link among the microbiota, the circadian lock and host metabolism.". Adding on to this, author Yuhao Wang (UT) explained: "The human gut is teeming with trillions of bacteria that help us digest our food, protect us from infection and produce certain vitamins. There is accumulating evidence that certain bacteria that live in our gut might predispose us to gain weight, especially when we consume a high fat, high sugar Western-style diet.". "Mice ...
From CHILD study: looked at bacterial 16S rRNA in stool samples at 2 times points in infancy, V3 region specifically. The gut microbiota at 3 months and 1 year were analyzed to determine which bacteria are present via RNA analysis. The gut microbiota at 3 months and 1 yr were analyzed to determine which bacteria are present via 16S RNA analysis. Microbiota results then compared to patient phenotype (wheezing or not, atopic/sensitized or not). They compared 319 children in the @CHILDSTUDY with 74 controls, 87 atopic only, 136 wheeze only and 22 subjects with both ...
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O papel da microbiota intestinal na patogênese das doenças inflamatórias intestinais / The role of the intestinal microbiota in the pathogenesis of inflammatory intestinal disease
The intestinal tract is inhabited by a large and diverse community of microbes collectively referred to as the gut microbiota. While the gut microbiota provides important benefits to its host, especially in metabolism and immune development, disturbance of the microbiota-host relationship is associa …
We are starting to explain the complex mechanisms of interaction and dynamics between the gut microbiota and its host.. Our data show that relatively minor changes in microbiota profiles or its metabolic activity induced by neonatal stress can have profound effects on host behaviour in adulthood.. It would be important to determine whether this also applies to humans.. For instance, whether we can detect abnormal microbiota profiles or different microbial metabolic activity in patients with primary psychiatric disorders, like anxiety and depression," ...
These data suggest that a loss of anti‐inflammatory (beneficial) bacteria and an increase in pro‐inflammatory bacteria with HIV infection has the potential to drive chronic inflammation observed in HIV‐infected individuals. Furthermore, our infectivity assays indicate a potential role of the MSM‐associated gut microbiota in disease transmission and progression ...
Recent observations indicate that acute enteric infections may contribute to various intestinal and extra-intestinal disorders long after elimination of the inciting microorganism. The mechanisms remain unclear. This review discusses how alterations to the gut microbiota by enteropathogens during the acute stage of an infection may at least in part contribute to these presentations. After providing a critical discussion of the biology of the human intestinal microbiota, the review presents recent data that illustrate how enteropathogens may activate latent virulence genes in commensal bacteria, disrupt the microbiota biofilm phenotype, and promote the release of pathobionts from the commensal biofilm. Evidence suggests that, in turn, these planktonic pathobionts may spontaneously translocate across the mucus and the gut epithelium to trigger, at least in part, the pro-inflammatory events that lead to these long-term, post-infectious sequelae.
During recent years, the composition of the gut microbiota (GM) has received increasing attention as a factor in the development of experimental inflammatory disease in animal models. Because increased variation in the GM might lead to increased variation in disease parameters, determining and reducing GM variation between laboratory animals may provide more consistent models. Both genetic and environmental aspects influence the composition of the GM and may vary between laboratory animal breeding centers and within an individual breeding center. This study investigated the variation in cecal microbiota in 8-wk-old NMRI and C57BL/6 mice by using denaturing gradient gel electrophoresis to profile PCR-derived amplicons from bacterial 16S rRNA genes. Comparison of the cecal microbiotas revealed that the similarity index of the inbred C57BL/6Sca strain was 10% higher than that of the outbred Sca:NMRI stock. Comparing C57BL/6 mice from 2 vendors revealed significant differences in the microbial ...
The microbiota plays a critical role in human health and disease. For instance, the gut microbiota aides in the digestion of foods, thereby contributing to our ability to metabolize compounds from our diet. Recently, it has become clear that the … Continue reading →. ...
Una microbiota és la totalitat de microorganismes, els seus elements genètics (genomes), i la interacció mediambiental dins un ambient biofísic particular. Es pot definir com una "comunitat ecològica de microorganismes comensals, simbiòtics i patògens"[1][2] que es troben en tots els organismes vius estudiats fins ara, des de plantes fins animals. Una microbiota inclou bacteris, arqueobacteris, protists, fongs i virus. Sha demostrat que les macrobiota són fonamentals per lhomeòstasi immunològica, hormonal i metabòlica del seu hoste. El terme sinònim microbioma descriu o bé els genomes col·lectius dels microorganismes que resideixen en un nínxol mediambiental, o bé els propis microorganismes. El terme "microbiota" va ser encunyat per Joshua Lederberg, qui argumentà que els microorganismes que habiten el cos humà podrien ser inclosos com a part del genoma humà, per la seva influència en la fisiologia humana. Es considerava que el cos humà conté unes 10 vegades més ...
Inflammation and microbiota are critical components of intestinal tumorigenesis. To dissect how the microbiota contributes to tumor distribution, we generated germ-free (GF) ApcMin/+ and ApcMin/+ ...
The composition of gut microbiota is altered in patients with Alzheimers disease, potentially supporting the inflammatory theory of the diseases pathogenesis, new research suggests.
The role of diet and gut microbiota in the pathophysiology of neurodegenerative diseases, such as Alzheimers, has recently come under intense investigatio
Recent investigations suggest that gut microbiota affects the brain activity through the microbiota-gut-brain axis under both physiological and pathological disease conditions like Parkinsons disease. Further dopamine synthesis in the brain is induced by dopamine producing enzymes that are controll …
Answers to common questions about getting a fecal microbiota transplant to help cure c diff and potentially to help ulcerative colitis.
TY - JOUR. T1 - Induction of Th17 cells by intestinal microbiota. AU - Honda, Kenya. PY - 2010. Y1 - 2010. UR - http://www.scopus.com/inward/record.url?scp=79952473134&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=79952473134&partnerID=8YFLogxK. M3 - Article. C2 - 21226338. AN - SCOPUS:79952473134. VL - 82. SP - 1060. EP - 1064. JO - Seikagaku. The Journal of Japanese Biochemical Society. JF - Seikagaku. The Journal of Japanese Biochemical Society. SN - 0037-1017. IS - 11. ER - ...
In the study of "Prostate Cancer Chemoprevention by Soy Isoflavones-Role of intestinal bacteria as the "second human genome" by Akaza H., posted in US National Library of Medicine National Institutes of Health, researchers found that the composition of intestinal microbiota can indicate the risk of disease to each individual. The concepts of biodynamics as employed by the Benziger Winery in California, which treats every part of an agricultural environment as a living, breathing entity, can be usefully employed in the construction of a system for cancer prevention, which seeks to utilize the relationship of coexistence (symbiosis) shared between people and intestinal symbiosis, that is microbiota. Changes in the incidence rate of cancer among Japanese emigrants to Hawaii demonstrate the impact of the changes in the living environment. This leads to the hypothesis that an intake of soy-derived food products and the metabolization of the isoflavones they contain by intestinal microbiota is one of ...
Every body part has its own composition of bacteria, which are called microbiota. These microbiota play an important role in human health.
Anaerobes comprise the predominant class of bacteria of the normal human microbiota (formerly termed "the normal human flora") that reside on mucous membranes and predominate in many infectious processes, particularly those arising from mucosal surfaces. These organisms generally cause disease subsequent to the breakdown of mucosal barriers and the leakage of the microbiota into normally sterile sites. Infections resulting from contamination by the microbiota are usually polymicrobial and involve both aerobic and anaerobic bacteria. However, the difficulties encountered in handling specimens in which anaerobes may be important and the technical challenges entailed in cultivating and identifying these organisms in clinical microbiology laboratories continue to leave the anaerobic etiology of an infectious process unproven in many cases. Therefore, an understanding of the types of infections in which anaerobes can play a role is crucial in selecting appropriate microbiologic tools to identify the ...
Proteins such as lipopolysaccharides (LPS) are a major component of the outer membrane of some bacteria, acting as a protective barrier, and their production is boosted by age. Unfortunately, they can also trigger the bodys immune system and cause inflammation. Levels of LPS production in the gut microbiota, and expression levels of inflamm-aging markers such as p16. P16 is a cell-cycle regulator, and is an inductor of senescence, the process of deterioration with age. With age, p16 expression increases in order to suppress stem cell proliferation and tissue regeneration. Results from the study showed that LPS lead to increased p16 expression in the colon of aged mice, along with increased activation of inflammatory markers. These results indicate that aging can accelerate inflamm-aging by inducing p16 expression in mice by increasing LPS levels in gut microbiota.. Such age-related gut microbiota modifications and imbalances are associated with inflamm-aging and immunosenescence, a decline in ...
The human body is inhabited by billions of symbiotic bacteria, carrying a diversity that is unique to each individual. The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. ...
How might knowledge regarding the gut and lung microbiome contribute to the field of intensive care medicine? Could there be therapeutic implications?
Daily News Thousands of Mutations Accumulate in the Human Brain Over a Lifetime Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.. ...
Gut Microbiota for Health is pleased to show its new Year at a Glance 2015 document, which covers the important developments in gut microbiota science.
To investigate the differences in the gut microbiota in abstinence and current drinking populations with AUD, by analyzing and comparing the gut microbiota of abstinent AUD participants, Abstinent Group to that of a group of currently drinking A ...
The alimentary tract represents an interface between the external environment and the body. Within it exists a complex polymicrobial ecology that interacts with the internal and external environment and has an important influence on health and diseas
Generalized dietary and lifestyle guidelines have been formulated and published for decades now from a variety of relevant agencies in an attempt to guide people towards healthy choices. As the pandemic rise in metabolic diseases continues to increase, it has become clear that the one-fit-for-all diet approach does not work and that there is a significant variation in inter-individual responses to diet and lifestyle interventions. Recent technological advances have given an unprecedented insight into the sources of this variation, pointing towards our genome and microbiome as potentially and previously under-explored culprits contributing to individually unique dietary responses ...
Today, the idea that gut bacteria affects a persons health is not new. Most of us know that these microbes influence digestion, allergies, and metabolism. Ne …