Nucleotide sequences of the four genes composing the T15 heavy chain variable region (VH) family of the CBA/J mouse have been determined. Comparison of these sequences with their published BALB/c and C57BL/10 homologues reveals that nucleotide differences found between given alleles of two strains, i.e., CBA/J and BALB/c, are observed in other family members of the same strain. We suggest that these patterns of sequence variation are most readily explained by gene interaction (conversion). Additionally, the sequence of a CBA/J hybridoma, 6G6, proposed to have been generated by gene conversion, is directly encoded by the CBA/J V11 gene indicating that the putative conversion has occurred meiotically in the germline. These results are consistent with the premise that gene correction is occurring frequently among members of this family and that such processes may contribute significantly to the evolution of Ig variable region genes even in the relatively short time frame of inbred strain derivation ...
CBA/N mice carry a recessive mutation at the X-linked immune deficiency (xid) locus that precludes their response to certain thymus-independent (TI) antigens. We have determined that xid is situated on the X-chromosome between the genes Ta (tabby) and Hyp (hypophosphatemia), genetic distances being Ta-6.6 +/- 1.8-xid-12.2 +/- 2.3-Hyp. ...
GtkWidget *dialog; dialog = gtk_recent_chooser_dialog_new ("Recent Documents", parent_window, GTK_STOCK_CANCEL, GTK_RESPONSE_CANCEL, GTK_STOCK_OPEN, GTK_RESPONSE_ACCEPT, NULL); if (gtk_dialog_run (GTK_DIALOG (dialog)) == GTK_RESPONSE_ACCEPT) { GtkRecentInfo *info; info = gtk_recent_chooser_get_current_item (GTK_RECENT_CHOOSER (dialog)); open_file (gtk_recent_info_get_uri (info)); gtk_recent_info_unref (info); } gtk_widget_destroy (dialog ...
I am also making a similar change for input methods. If a user is using ibus, they should not have to manually install ibus-gtk (the gtk2 version) if they later install a gtk2 app. And I dont think its a good idea to have gtk2 recommend every gtk2 theme engine and input method. , I see two possibilities in this case (feel free to add more, of course): The problem here is a bit theoretical since there doesnt seem to be any gtk3 version of Oxygen (at least not in Debian) and therefore, the package is not very useful since most maintained gtk apps use gtk3 now. So let me substitute with a better example: c) In the near future, it will be possible to install Debian GNOME without gtk2 pre-installed. A Debian GNOME user installs the Numix theme and makes it their default theme. A few weeks later, the user decides to install a gtk2 app like Inkscape. I think its wrong to require the user to manually install a theoretical numix-gtk2-theme package to fix their theming. I also think its wrong to ...
Kinetic analysis of virus titers in newborn inoculated CBA/J mice. Spleens from neonatally infected mice were harvested, homogenized, and titered for polyoma vi
One year out from the expiration of the NHLs collective-bargaining agreement, theres both optimism and uncertainty among the two sides that will be looking to reach a deal. The NHL, for its part, met with club general managers this summer in a number of individual meetings and CBA work
With 373 games remaining in the regular season, the CBA is on track to break last years attendance record of 1.8M. This years numbers are 8,118 ahead of last seasons average of 3,895 per game, a
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Tcl script which is executed in the global scope if the "show-help" signal is received, which is normally the case if the user presses F1 or Ctrl-F1. Before evaluation the following percent strings are substituted: %w widget ...
Lewis, R. and Behnke, Jerzy M. and Cassidy, J.P. and Stafford, P. and Murray, N. and Holland, Celia V. (2007) The migration of Ascaris suum larvae, and the associated pulmonary inflammatory response in susceptible C57BL/6j and resistant CBA/Ca mice. Parasitology, 134 (9). pp. 1301-1314. ISSN 0031-1820 ...
With the Cellometer Vision CBA, just 20 microliter of sample is added to the Cellometer Counting Chamber. Imaging and analysis of GFP expression is completed in less than 60 seconds.
Dear CBAers, TT Ari is continuing to decline towards its historical V=15.5 low state, and in fact might be already there. Some data has trickled in - just a little, but enough to make me awfully greedy for more. As usual, being a CBAer deep in my heart, Im most desirous of long nightly time series - which, after being spliced together around the globe, will yield a superb record of periodic signals in the light curve. Naturally thatll take a while to assemble. But Im already surprised to see the very strong flickering/QPOs that continues in the light curve. Its not obvious where this flickering arises. The accretion rate must be much lower now, but the hot WD should still be plenty luminous - itll take months/years/decades for the WD, heated by centuries (at least) of accretion, to cool off. So why doesnt the WD now (presumably a more or less constant source) dominate the faded disk? This question will perhaps be best addressed by spectrophotometry, which can parse the secondary+disk+WD ...
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struct GtkBindingEntry { /* key portion */ guint keyval; GdkModifierType modifiers; GtkBindingSet *binding_set; guint destroyed : 1; guint in_emission : 1; guint marks_unbound : 1; GtkBindingEntry *set_next; GtkBindingEntry *hash_next; GtkBindingSignal *signals ...
Determines the tooltips and the widget they belong to from the window in which they are displayed. This function is mostly intended for use by accessibility technologies; applications should have little use for it.. ...
The local lymph node assay using 5-bromo-2-deoxyuridine (BrdU) with flow cytometry (LLNA: BrdU-FCM) is a modified LLNA that is used to identify skin sensitizers by counting BrdU-incorporated lymph node cells (LNCs) with flow cytometry. Unlike other LLNA methods (OECD TG 429, 442A and 442B) in which the CBA/J mouse strain is used, LLNA: BrdU-FCM was originally designed to be compatible with BALB/c, a mouse strain that is more widely used in many countries. To justify the substitution of CBA/J for BALB/c, the equivalence of the test results between two strains shall be established prior to the official implementation of LLNA: BrdU-FCM. This study aims to compare the test results of LLNA: BrdU-FCM produced in BALB/c mice with those in CBA/J mice for 18 reference substances, including 13 sensitizers and 5 non-sensitizers, listed in OECD Test Guideline 429. Based on the LLNA: BrdU-FCM test procedure, we selected an appropriate solvent and then performed preliminary tests to determine the ...
Myeloid leukemia (ML) is one of the major health concerns from exposure to radiation. However, the risk assessment for developing ML after exposure to space radiation remains uncertain. To reduce the uncertainty in risk prediction for ML, a much increased understanding of space radiation-induced changes in the target cells, i.e., hematopoietic stem/progenitor cells (HSPCs), is critically important. We used the label-free quantitative mass spectrometry (LFQMS) proteomic approach to determine the expression of protein in HSPC-derived myeloid colonies obtained at an early time-point (one week) and a late time-point (six months) after an acute whole body exposure of CBA/CaJ mice to a total dose of 0, 0.1, 0.25, or 0.5 Gy of heavy-ion titanium (48Ti ions), which are the important component of radiation found in the space environment. Mice exposed to 0 Gy of 48Ti ions served as non-irradiated sham controls. There were five mice per treatment groups at each harvest time. The Trans-Proteomic Pipeline ...
... Cynthia Prosen (Graduate Studies, Research and Continuing Education) and former NMU student Sarah Kimar, who now attends graduate school at Wayne State University, co-authored an article titled Auditory filter shapes of CBA/CaJ mice: Behavioral assessments. It was published in the Journal of the Acoustical Society of America. The article highlighted results of a study that suggested auditory filtering effects in adult CBA/CaJ mice are similar to normal processes in other mammalian species and provide an excellent model of human presbycusis, or age-related hearing loss.. Two articles by Neil Cumberlidge (Biology) were published in the Rapid Assessment Program (RAP) Bulletin of Biological Assessment by Conservation International in Washington, DC. The articles relay the results of a three-week biodiversity survey conducted by Cumberlidge last year of the decapod crustaceans of mangrove and freshwater ecosystems in Guinea, West Africa. The RAP Bulletin is in French and the title of ...
TY - JOUR. T1 - T cell abnormalities in NZB mice occur independently of autoantibody production. AU - Taurog, J. D.. AU - Raveche, E. S.. AU - Smathers, P. A.. AU - Glimcher, L. H.. AU - Huston, D. P.. AU - Hansen, C. T.. AU - Steinberg, A. D.. PY - 1981/5/15. Y1 - 1981/5/15. N2 - By means of a series of crosses and backcrosses, ZB.CBA/N mice were prepared bearing largely NZB autosomal genes, but having X chromosomes derived only from CBA/N mice. The CBA/N X chromosome carries a gene, xid, that is associated with the lack of a B cell subset necessary for most of the spontaneous autoantibody production by NZB mice. These ZB.CBA/N mice failed to develop autoantibodies to T cells, erythrocytes, or DNA. The availability of mice that were mostly NZB, but which failed to make autoantibodies, especially anti-T cell antibodies, allowed us to study possible T cell regulatory defects in NZB mice in the absence of either antibodies reactive with such T cells or other autoantibodies. We found that such mice ...
Downloadable! Cost-benefit analysis (CBA) is often used when many transport investments need to be ranked against each other, for example in national investment planning. However, results are often questioned on claims that the ranking depends crucially on uncertain assumptions about the future, and on methodologically or ethically contestable trade-offs of different types of benefits relative to each other. This paper explores the robustness of CBA rankings of transport investments with respect to two types of uncertainties: relative benefit valuations and scenario assumptions related to car ownership, characteristics and costs. The study is based on CBAs of 479 suggested road and rail investments in Sweden that have been shortlisted for possible inclusion in the national transport investment plan. The CBA ranking turns out to be robust to variations in the studied scenario assumptions. The CBA ranking also turns out to be robust to changes in the relative valuations of different types of benefits -
This course helps the energy industry managers and executives to better use the tool commonly referred to as "cost-benefit analysis" or CBA. As a formal assessment of an organizations project costs and benefits, CBA attempts to measure and compare the efficiency of project options. This type of analysis has become standard practice in project analysis and program evaluation-particularly in cases where there are new strategic or capital investments. The goal of the course is to provide the participants with the conceptual foundations and practical skills they will need to be thoughtful consumers and producers of CBA.. The class will draw on qualitative, quantitative, and analytic skills. As a practical matter, a basic familiarity with the energy industry, microeconomic theory, statistics, and algebra is assumed.. ...
Caj z Hlohu information about active ingredients, pharmaceutical forms and doses by Megafyt-R, Caj z Hlohu indications, usages and related health products lists
View Wfs1/Wfs1 Tg(Ins2-cre)23Herr/0 involves: 129X1/SvJ * C57BL/6J * CBA/J: phenotypes, images, diseases, and references.
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A GtkCellRendererPixbuf can be used to render an image in a cell. It allows to render either a given GdkPixbuf (set via the "pixbuf" property) or a named icon (set via the "icon-name" property).. To support the tree view, GtkCellRendererPixbuf also supports rendering two alternative pixbufs, when the "is-expander" property is ...
struct AgsConfigClass { GObjectClass object; void (*load_defaults)(AgsConfig *config); void (*set_value)(AgsConfig *config, gchar *group, gchar *key, gchar *value); gchar* (*get_value)(AgsConfig *config, gchar *group, gchar *key ...
In a local lymph node assay according to OECD guideline 426 the skin senitisation potential of NaFeEDTA was evaluated. Three concentrations of FeNaEDTA (10%, 25% and 50%, w/w) dissolved in acetone/olive oil (4:1 v/v) were tested in six female CBA mice per group and compared to a vehicle control group. In addition, a positive control group (30% solution v/v of hexyl cinnamic aldehyde in acetone/olive oil (4:1 v/v)) was employed. Open application of 25 μL of the appropriate dilution of the test item, the vehicle alone or the positive control (as appropriate) were administered to the dorsum of each ear on 3 consecutive days. On test day 4 lymph node cell count, ear weight (punch biopsies), ear swelling and weight of the lymph nodes were measured. The positive control group caused the expected increases in lymph node cell count and ear weights (statistically significant at p ≤ 0.01). The values for the stimulation index of lymph node cell count and ear weight were 1.5 and 1.2, respectively. ...
Theres a weird sort of dissonance in todays Australian Financial Review.. On the front page, CBA CEO Ian Narev argues that CBA culture is "strong".. Meanwhile, a detailed Neil Chenoweth feature breaks down how AUSTRAC thinks CBA was regularly breaching the very well-known legal requirement to report all cash transactions above $10,000. AUSTRAC has counted 53,506 breaches, an amount which in technical banking language is known as "a truckload". Real crooks seem to have been behind a number of these breaches, using techniques such as "cuckoo smurfing". And six of the breaches related to customers the bank itself had identified as posing terrorism risks.. The most damning aspect of the chronology is how long it took the CBA to react once problems in its systems became clear. The AUSTRAC account suggests that after realising its errors in April 2015, CBA went on failing to report suspicious transfers until January of this year. All this screams "governance failure".. In The CEO Magazine today I ...
Clearance of various bacteria isolated from portal and systemic blood of mice was evaluated and compared. All portal blood strains, including Escherichia coli and enterococci were eliminated more rapidly from the circulation than were strains isolated from systemic blood, including Pseudomonas aeruginosa. With mannose-type lectin, mannose or fucose residues that mediated lectinophagocytosis were detected on the surfaces of most portal strains by agglutination tests. Blood clearance of Esch. coli H21 was inhibited by prior injection of mannose into mice, suggesting that the clearance of this strain was mediated by mannose-type lectin on the surface of tissue macrophages. However, no inhibition of clearance of any other strains was observed by the injection of mannose, galactose, or fucose into mice, nor by pre-incubation of bacteria with mannose. Blood clearance of some portal strains was significantly faster in CBA/J mice than in CBA/N mice with B cell immune deficiency, indicating that immunoglobulin
BEGIN PGP SIGNED MESSAGE----- Hash: SHA1 Format: 1.8 Date: Fri, 20 May 2011 10:13:26 +0200 Source: gtk2-engines-oxygen Binary: gtk2-engines-oxygen Architecture: source amd64 Version: 1.0.5-1 Distribution: unstable Urgency: low Maintainer: Debian KDE Extras Team ,[email protected], Changed-By: Kai Wasserbäch ,[email protected], Description: gtk2-engines-oxygen - Oxygen widget theme for GTK+-based applications Changes: gtk2-engines-oxygen (1.0.5-1) unstable; urgency=low . * New upstream version. * debian/gbp.conf: Make signed tags the default behaviour. * debian/control: Bumped Standards-Version to 3.9.2, no further changes required. * debian/copyright: Added myself to the Debian packaging section. Checksums-Sha1: b66dc390c9088531f574f87689d9a5e759f52d33 1905 gtk2-engines-oxygen_1.0.5-1.dsc e10b89352441d0de1b57c18581984483b3064d04 133854 gtk2-engines-oxygen_1.0.5.orig.tar.bz2 9007c32f794c893ac208f2d0e3afb6ea2b043be3 2901 gtk2-engines-oxygen_1.0.5-1.debian.tar.bz2 ...
Abstract: Сhronic g-radiation (1 - 16 sGr/day) of mice there is the increase of antioxidant activity and the decrease of lipid peroxidation. The wasa correlation between investigated parameters and the dose of irradiation. The results suggest, that chronic g-radiation causes damage of processes in spleen of CBA mice accompanied by subseguent augmentation of reparative processess ...
Muller, M and Welcker, E, "Akzeleration von mammakarzinomtransplantaten bei cba/bln-mausen durch vorbehandlung mit kleinen dosen vitaler isologer tumorzellen." (1965). Subject Strain Bibliography 1965. 1099 ...
ISOLUTE® CBA is a weak cation exchange sorbent, used to extract strongly basic (e.g. quaternary amines) and polybasic analytes from aqueous samples.
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imp_entry-,signal_connect( scroll-event =, sub { my $eventscroll = Gtk2-,get_current_event ; my $scrolldirection = $eventscroll-,direction() ; if( $scrolldirection eq up ) { $imp_entry-,set_text( $imp_entry-,get_text() - 1 ) ; } elsif( $scrolldirection eq down ) { $imp_entry-,set_text( $imp_entry-,get_text() + 1 ) ; } return FALSE ...
Emitted right before the printing will start. You should read the information from the widget and update the content based on it if necessary. The widget is not guaranteed to be valid at a later time.. ...
AgsExpander is a composite widget containing a GtkTable. It is mainly used to layout childs in rows and columns that can be expanded.. ...
Return the number of the mouse button that triggered the navigation, or 0 if the navigation was not started by a mouse event.. ...
Accessible surface proteins of thymus-derived lymphocytes (T-cells) of normal CBA mice and bone-marrow-derived lymphocytes (B-cells) of congenitally athymic nu/nu mice were analysed. The surfaces of lymphocytes were radioiodinated by using the enzyme lactoperoxidase (EC 1.11.1.7), then solubilized either in acid-urea or in the non-ionic detergent Nonidet P-40. These lysates were then precipitated with antisera specific to either immunoglobulin or the θ-alloantigen in order to assess the presence of these surface markers. Comparable amounts of radioactivity in proteins specifically precipitable as immunoglobulin were obtained from T-lymphocytes and B-lymphocytes when the cells were disrupted by acid-urea. This immunoglobulin had mol. wt. approx. 180000 and was composed of light chains and μ-type heavy chains. When radioiodinated lymphocytes were solubilized with Nonidet P-40, 3-4% of radioiodinated high-molecular-weight protein of B-cells consisted of immunoglobulin, a result similar to that ...
If we assume that Fc and EVP are constant between C57BL/6J, BALB/cJ, and CBA/J mice, then the regression in Figure 5A predicts (excluding the outlier) that Fc = 0.068 ± 0.044 μL/min and EVP = 7.1 ± 3.2 mm Hg (mean ± SD). Whether Fc and EVP truly are constant between strains is an open question. However, the strong agreement between Equation 5 and our data (R2 = 0.70, N = 13 mice) suggests that Fc and EVP are reasonably consistent between C57BL/6, BALB/cJ, and CBA/J strains, or that any variation in Fc and EVP between strains has relatively minor influence (≤30%) on IOP compared to the principal dependence of IOP on 1/C. We point out that a portion of the remaining 30% influence is likely attributable to experimental uncertainty in the measurements themselves. The value of EVP estimated by linear regression (7.1 mm Hg) agrees fairly well, but tends to be slightly higher than published values from the same strains using the blood-reflux technique 21 (compare to 5.4 mm Hg for BALB/cJ 8 and ...
Normal B cells responsive to thymus independent-type 1 Ags (TI-1) are resistant to low doses of ionizing radiation in vivo (200-300 cGy), compared with TI-1 responsive B cells of mice with the CBA/N X-linked immunodeficiency (xid). This difference in radiosensitivity is an intrinsic B cell property; normal B cells adoptively transferred into xid mice remain TI-1-responsive after irradiation in situ. Because irradiation induces programmed cell death (PCD) in lymphocytes, we determined whether PCD were regulated differently in normal and xid B cells. B cells isolated immediately after irradiation from normal or xid donors when cultured without stimulators became apoptotic with the same kinetics and to the same extent, showing that apoptosis was induced equally in both populations. Apoptosis could be suppressed and mitogenesis could be induced frequently, however, if irradiated B cells were cultured with B cell activators. When activators using separate signal transduction pathways were compared, a